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David Gisselsson

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Gisela Lundberg; Ingrid Øra; Daniel Sehic; Rogier Versteeg; Yuesheng Jin; David Gisselsson
Intratumour diversity of chromosome copy numbers in neuroblastoma mediated by on-going chromosome loss from a polyploid state.
Susanne Magnusson; David Gisselsson; Ulf Kristoffersson; Thomas Wiebe; Ake Borg; Håkan Olsson
Prevalence of germline TP53 mutations and history of Li-Fraumeni syndrome in families with childhood adrenocortical tumors, choroid plexus tumors, and rhabdomyosarcoma: a population-based survey.
Daniel Sehic; Jenny Karlsson; Bengt Sandstedt; David Gisselsson
SIX1 protein expression selectively identifies blastemal elements in Wilms tumor.

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All Publications

2013: Gisela Lundberg; Ingrid Øra; Daniel Sehic; Rogier Versteeg; Yuesheng Jin; David Gisselsson
Intratumour diversity of chromosome copy numbers in neuroblastoma mediated by on-going chromosome loss from a polyploid state.
PloS one 2013;8(3):e59268.
2012: Susanne Magnusson; David Gisselsson; Ulf Kristoffersson; Thomas Wiebe; Ake Borg; Håkan Olsson
Prevalence of germline TP53 mutations and history of Li-Fraumeni syndrome in families with childhood adrenocortical tumors, choroid plexus tumors, and rhabdomyosarcoma: a population-based survey.
Pediatric blood & cancer 2012;59(5):846-53.
2012: Daniel Sehic; Jenny Karlsson; Bengt Sandstedt; David Gisselsson
SIX1 protein expression selectively identifies blastemal elements in Wilms tumor.
Pediatric blood & cancer 2012;59(1):62-8.
2012: Sofie Mohlin; Kenneth Nilsson; Tor Olofsson; Ingrid Øra; Michael Andäng; David Gisselsson; Alexander Pietras; Caroline Wigerup; Sven Påhlman
Tumor-initiating cells in childhood neuroblastoma--letter.
Cancer research 2012;72(3):821-2; author reply 823.
2012: Jan J Molenaar; Ingrid Øra; Frank Speleman; Peter G van Sluis; Huib N Caron; Katleen De Preter; Marli E Ebus; David Gisselsson; Jan Koster; Ellen M Westerhout; Rogier Versteeg
Copy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis.
Genes, chromosomes & cancer 2012;51(1):10-9.
2011: Gisela Lundberg; Daniel Sehic; John-Kalle Länsberg; Ingrid Øra; Attila Frigyesi; Victoria Castel; Samuel Navarro; Marta Piqueras; Tommy Martinsson; Rosa Noguera; David Gisselsson
Alternative lengthening of telomeres--an enhanced chromosomal instability in aggressive non-MYCN amplified and telomere elongated neuroblastomas.
Genes, chromosomes & cancer 2011;50(4):250-62.
2011: David Gisselsson
Aneuploidy in cancer: sudden or sequential?
Cell cycle (Georgetown, Tex.) 2011;10(3):359-61.
2011: David Gisselsson
Intratumor diversity and clonal evolution in cancer--a skeptical standpoint.
Advances in cancer research 2011;112():1-9.
2011: David Gisselsson
Mechanisms of whole chromosome gains in tumors--many answers to a simple question.
Cytogenetic and genome research 2011;133(2-4):190-201.
2010: David Gisselsson; David Lindgren; Linda Holmquist Mengelbier; Ingrid Øra; Herman Yeger
Genetic bottlenecks and the hazardous game of population reduction in cell line based research.
Experimental cell research 2010;316(20):3379-86.
2010: David Gisselsson; Yuesheng Jin; David Lindgren; Johan Persson; Lennart Gisselsson; Sandra Hanks; Daniel Sehic; Linda Holmquist Mengelbier; Ingrid Øra; Nazneen Rahman; Fredrik Mertens; Felix Mitelman; Nils Mandahl
Generation of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(47):20489-93.
2010: Linda Holmquist Mengelbier; Jenny Karlsson; David Lindgren; Ingrid Øra; Margareth Isaksson; Ildiko Frigyesi; Attila Frigyesi; Johannes Bras; Bengt Sandstedt; David Gisselsson
Deletions of 16q in Wilms tumors localize to blastemal-anaplastic cells and are associated with reduced expression of the IRXB renal tubulogenesis gene cluster.
The American journal of pathology 2010;177(5):2609-21.
2009: S Gebre-Medhin; Karin Broberg; Tord Jonson; Ludmila Gorunova; F Vult von Steyern; Otte Brosjö; Yuesheng Jin; David Gisselsson; Ioannis Panagopoulos; Nils Mandahl; Fredrik Mertens
Telomeric associations correlate with telomere length reduction and clonal chromosome aberrations in giant cell tumor of bone.
Cytogenetic and genome research 2009;124(2):121-7.
2009: Daniel Bexell; Salina Gunnarsson; Ariane Tormin; Anna Darabi; David Gisselsson; Laurent Roybon; Stefan Scheding; Johan Bengzon
Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(1):183-90.
2008: David Gisselsson
Classification of chromosome segregation errors in cancer.
Chromosoma 2008;117(6):511-9.
2008: Ylva Stewénius; Yuesheng Jin; Ingrid Øra; Ioannis Panagopoulos; Emely Möller; Fredrik Mertens; Bengt Sandstedt; Jan Alumets; Måns Akerman; Johannes Hm Merks; Jan de Kraker; David Gisselsson
High-resolution molecular cytogenetic analysis of Wilms tumors highlights diagnostic difficulties among small round cell kidney tumors.
Genes, chromosomes & cancer 2008;47(10):845-52.
2008: Alexander Pietras; David Gisselsson; Ingrid Øra; R Noguera; Siv Beckman; S Navarro; Sven Påhlman
High levels of HIF-2alpha highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche.
The Journal of pathology 2008;214(4):482-8.
2008: Gisela Lundberg; Anders H Rosengren; Ulf Håkanson; Henrik Stewénius; Yuesheng Jin; Ylva Stewénius; Sven Påhlman; David Gisselsson
Binomial mitotic segregation of MYCN-carrying double minutes in neuroblastoma illustrates the role of randomness in oncogene amplification.
PloS one 2008;3(8):e3099.
2008: Johan Rebetz; Dongping Tian; Annette Persson; Bengt Widegren; Leif G Salford; Elisabet Englund; David Gisselsson; Xiaolong Fan
Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma.
PloS one 2008;3(4):e1936.
2008: David Gisselsson; Ulf Håkanson; Patrick Stoller; Dominik Marti; Yuesheng Jin; Anders H Rosengren; Ylva Stewénius; Fredrik Kahl; Ioannis Panagopoulos
When the genome plays dice: circumvention of the spindle assembly checkpoint and near-random chromosome segregation in multipolar cancer cell mitoses.
PloS one 2008;3(4):e1871.
2007: Eva Lindberg; Annette Persson; Ingrid Øra; Fredrik Mertens; Elisabet Englund; David Gisselsson
Concurrent gain of 17q and the MYC oncogene in a medullomyoblastoma.
Neuropathology : official journal of the Japanese Society of Neuropathology 2007;27(6):556-60.
2007: Ylva Stewénius; Yuesheng Jin; Ingrid Øra; Jan de Kraker; Johannes Bras; Attila Frigyesi; Jan Alumets; Bengt Sandstedt; Alan K Meeker; David Gisselsson
Defective chromosome segregation and telomere dysfunction in aggressive Wilms' tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(22 Pt 1):6593-602.
2007: C Glanz; Johan Rebetz; Ylva Stewénius; A Persson; Elisabet Englund; Nils Mandahl; Fredrik Mertens; Leif G Salford; Bengt Widegren; Xiaolong Fan; David Gisselsson
Genetic intratumour heterogeneity in high-grade brain tumours is associated with telomere-dependent mitotic instability.
Neuropathology and applied neurobiology 2007;33(4):440-54.
2007: David Gisselsson
Cancer stem cells: differentiation block or developmental back-tracking?
Seminars in cancer biology 2007;17(3):189-90.
2007: Yuesheng Jin; Ylva Stewénius; David Lindgren; Attila Frigyesi; Olga Calcagnile; Tord Jonson; Anna Edqvist; Nina Larsson; Lena Maria Lundberg; Gunilla Chebil; Fredrik Liedberg; Sigurdur Gudjonsson; Wiking Månsson; Mattias Höglund; David Gisselsson
Distinct mitotic segregation errors mediate chromosomal instability in aggressive urothelial cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(6):1703-12.
2007: O Calcagnile; David Gisselsson
Telomere dysfunction and telomerase activation in cancer--a pathological paradox?
Cytogenetic and genome research 2007;118(2-4):270-6.
2007: David Gisselsson; Gisela Lundberg; Ingrid Øra; Mattias Höglund
Distinct evolutionary mechanisms for genomic imbalances in high-risk and low-risk neuroblastomas.
Journal of carcinogenesis 2007;6():15.
2007: Mona Ellaithi; David Gisselsson; Therese Nilsson; Atif Elagib; Imad Fadl-Elmula; Mashair Abdelgadir
A case of Cornelia de Lange syndrome from Sudan.
BMC pediatrics 2007;7():6.
2006: Charlotte Jin; Yuesheng Jin; David Gisselsson; Johan Wennerberg; T S Wah; B Strömbäck; Y-L Kwong; Fredrik Mertens
Molecular cytogenetic characterization of the 11q13 amplicon in head and neck squamous cell carcinoma.
Cytogenetic and genome research 2006;115(2):99-106.
2006: Ylva Stewénius; Hans J Tanke; Joop Wiegant; David Gisselsson
Cryptic terminal chromosome rearrangements in colorectal carcinoma cell lines detected by subtelomeric FISH analysis.
Cytogenetic and genome research 2006;114(3-4):257-62.
2006: Mona Ellaithi; David Gisselsson; Therese Nilsson; S Abd El-Fatah; T Ali; Atif Elagib; Muntaser Ibrahim; Imad Fadl-Elmula
A del(X)(p11) carrying SRY sequences in an infant with ambiguous genitalia.
BMC pediatrics 2006;6():11.
2006: Mona Ellaithi; Therese Nilsson; David Gisselsson; Atif Elagib; H Eltigani; Imad Fadl-Elmula
Female genital mutilation of a karyotypic male presenting as a female with delayed puberty.
BMC women's health 2006;6():6.
2005: Mattias Höglund; David Gisselsson; Nils Mandahl; Felix Mitelman
Ewing tumours and synovial sarcomas have critical features of karyotype evolution in common with epithelial tumours.
International journal of cancer. Journal international du cancer 2005;116(3):401-6.
2005: David Gisselsson
Mitotic instability in cancer: is there method in the madness?
Cell cycle (Georgetown, Tex.) 2005;4(8):1007-10.
2005: David Gisselsson; Chunbo Shao; Cathy M Tuck-Muller; Suzana Sogorovic; Eva Pålsson; Dominique Smeets; Melanie Ehrlich
Interphase chromosomal abnormalities and mitotic missegregation of hypomethylated sequences in ICF syndrome cells.
Chromosoma 2005;114(2):118-26.
2005: Ylva Stewénius; Ludmila Gorunova; Tord Jonson; Nina Larsson; Mattias Höglund; Nils Mandahl; Fredrik Mertens; Felix Mitelman; David Gisselsson
Structural and numerical chromosome changes in colon cancer develop through telomere-mediated anaphase bridges, not through mitotic multipolarity.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(15):5541-6.
2005: Mattias Höglund; Attila Frigyesi; Torbjörn Säll; David Gisselsson; Felix Mitelman
Statistical behavior of complex cancer karyotypes.
Genes, chromosomes & cancer 2005;42(4):327-41.
2005: David Gisselsson; Mattias Höglund
Connecting mitotic instability and chromosome aberrations in cancer--can telomeres bridge the gap?
Seminars in cancer biology 2005;15(1):13-23.
2005: Asa Petersén; Ylva Stewénius; Maria Björkqvist; David Gisselsson
Euploidy in somatic cells from R6/2 transgenic Huntington's disease mice.
BMC cell biology 2005;6():34.
2005: David Gisselsson; Mei Lv; Sai Wah Tsao; Cornelia Man; Charlotte Jin; Mattias Höglund; Yok-Lam Kwong; Yuesheng Jin
Telomere-mediated mitotic disturbances in immortalized ovarian epithelial cells reproduce chromosomal losses and breakpoints from ovarian carcinoma.
Genes, chromosomes & cancer 2005;42(1):22-33.
2004: Mattias Höglund; David Gisselsson; Gunnar B Hansen; Felix Mitelman
Statistical dissection of cytogenetic patterns in lung cancer reveals multiple modes of karyotypic evolution independent of histological classification.
Cancer genetics and cytogenetics 2004;154(2):99-109.
2004: Mattias Höglund; David Gisselsson; Maria Soller; Gunnar B Hansen; Peter Elfving; Felix Mitelman
Dissecting karyotypic patterns in renal cell carcinoma: an analysis of the accumulated cytogenetic data.
Cancer genetics and cytogenetics 2004;153(1):1-9.
2004: David Gisselsson; Ludmila Gorunova; Mattias Höglund; Nils Mandahl; Peter Elfving
Telomere shortening and mitotic dysfunction generate cytogenetic heterogeneity in a subgroup of renal cell carcinomas.
British journal of cancer 2004;91(2):327-32.
2004: Attila Frigyesi; David Gisselsson; Gunnar B Hansen; Maria Soller; Felix Mitelman; Mattias Höglund
A model for karyotypic evolution in testicular germ cell tumors.
Genes, chromosomes & cancer 2004;40(3):172-8.
2004: Mattias Höglund; David Gisselsson; Gunnar B Hansen; Felix Mitelman
Wilms tumors develop through two distinct karyotypic pathways.
Cancer genetics and cytogenetics 2004;150(1):9-15.
2004: Mattias Höglund; Charlotte Jin; David Gisselsson; Gunnar B Hansen; Felix Mitelman; Fredrik Mertens
Statistical analyses of karyotypic complexity in head and neck squamous cell carcinoma.
Cancer genetics and cytogenetics 2004;150(1):1-8.
2004: David Gisselsson; Eva Pålsson; Christina Yu; Fredrik Mertens; Nils Mandahl
Mitotic instability associated with late genomic changes in bone and soft tissue tumours.
Cancer letters 2004;206(1):69-76.
2004: Thérèse Nilsson; Mona Ellaithi; Muntaser Ibrahim; Imad Fadl Elmula; David Gisselsson
[Sudanese cytogeneticists--vision of a new kind of assistance].
Läkartidningen 2004;101(8):702-5.
2004: Fredrik Mertens; Ioannis Panagopoulos; Tord Jonson; David Gisselsson; Margareth Isaksson; Henryk A Domanski; Nils Mandahl
Retained heterodisomy for chromosome 12 in atypical lipomatous tumors: implications for ring chromosome formation.
Cytogenetic and genome research 2004;106(1):33-8.
2004: Mattias Höglund; David Gisselsson; Gunnar B Hansen; Valerie A White; Torbjörn Säll; Felix Mitelman; Douglas E Horsman
Dissecting karyotypic patterns in malignant melanomas: temporal clustering of losses and gains in melanoma karyotypic evolution.
International journal of cancer. Journal international du cancer 2004;108(1):57-65.
2003: Attila Frigyesi; David Gisselsson; Felix Mitelman; Mattias Höglund
Power law distribution of chromosome aberrations in cancer.
Cancer research 2003;63(21):7094-7.
2003: Mattias Höglund; David Gisselsson; Gunnar B Hansen; Torbjörn Säll; Felix Mitelman
Ovarian carcinoma develops through multiple modes of chromosomal evolution.
Cancer research 2003;63(12):3378-85.
2003: Clelia Tiziana Storlazzi; Fredrik Mertens; Nils Mandahl; David Gisselsson; Margareth Isaksson; Pelle Gustafson; Henryk A Domanski; Ioannis Panagopoulos
A novel fusion gene, SS18L1/SSX1, in synovial sarcoma.
Genes, chromosomes & cancer 2003;37(2):195-200.
2003: David Gisselsson
Chromosome instability in cancer: how, when, and why?
Advances in cancer research 2003;87():1-29.
2002: Mattias Höglund; David Gisselsson; Gunnar B Hansen; Torbjörn Säll; Felix Mitelman; Mef Nilbert
Dissecting karyotypic patterns in colorectal tumors: two distinct but overlapping pathways in the adenoma-carcinoma transition.
Cancer research 2002;62(20):5939-46.
2002: David Gisselsson
Tumour morphology--interplay between chromosome aberrations and founder cell differentiation.
Histology and histopathology 2002;17(4):1207-12.
2002: David Gisselsson; Tord Jonson; C Yu; Carmo Martins; Nils Mandahl; Joop Wiegant; Yuesheng Jin; Fredrik Mertens; Charlotte Jin
Centrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeres.
British journal of cancer 2002;87(2):202-7.
2002: Mattias Höglund; David Gisselsson; Torbjörn Säll; Felix Mitelman
Coping with complexity. multivariate analysis of tumor karyotypes.
Cancer genetics and cytogenetics 2002;135(2):103-9.
2002: Mattias Höglund; David Gisselsson; Gunnar B Hansen; Torbjörn Säll; Felix Mitelman
Multivariate analysis of chromosomal imbalances in breast cancer delineates cytogenetic pathways and reveals complex relationships among imbalances.
Cancer research 2002;62(9):2675-80.
2002: Nils Mandahl; Pelle Gustafson; Fredrik Mertens; Måns Akerman; Bo Baldetorp; David Gisselsson; Sakari Knuutila; Henrik C F Bauer; Olle Larsson
Cytogenetic aberrations and their prognostic impact in chondrosarcoma.
Genes, chromosomes & cancer 2002;33(2):188-200.
2002: David Gisselsson; Eva Pålsson; Mattias Höglund; Henryk A Domanski; Fredrik Mertens; Nikos Pandis; Raf Sciot; Paola Dal Cin; Julia A Bridge; Nils Mandahl
Differentially amplified chromosome 12 sequences in low- and high-grade osteosarcoma.
Genes, chromosomes & cancer 2002;33(2):133-40.
2001: David Gisselsson; Tord Jonson; Asa Petersén; Bodil Strömbeck; Paola Dal Cin; Mattias Höglund; Felix Mitelman; Fredrik Mertens; Nils Mandahl
Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12683-8.
2001: Mattias Höglund; David Gisselsson; Nils Mandahl; Bertil Johansson; Fredrik Mertens; Felix Mitelman; Torbjörn Säll
Multivariate analyses of genomic imbalances in solid tumors reveal distinct and converging pathways of karyotypic evolution.
Genes, chromosomes & cancer 2001;31(2):156-71.
2001: Charlotte Jin; Carmo Martins; Yuesheng Jin; Joop Wiegant; Johan Wennerberg; Michael Dictor; David Gisselsson; Bodil Strömbeck; Isabel Fonseca; Felix Mitelman; Hans J Tanke; Mattias Höglund; Fredrik Mertens
Characterization of chromosome aberrations in salivary gland tumors by FISH, including multicolor COBRA-FISH.
Genes, chromosomes & cancer 2001;30(2):161-7.
2001: David Gisselsson
Refined characterisation of chromosome aberrations in tumours by multicolour banding and electronic mapping resources.
Methods in cell science : an official journal of the Society for In Vitro Biology 2001;23(1-3):23-8.
2000: David Gisselsson; Mattias Höglund
Putting chromosome aberrations on the map.
Trends in genetics : TIG 2000;16(9):420-2.
2000: David Gisselsson; Nils Mandahl; Eva Pålsson; Ludmila Gorunova; Mattias Höglund
Locus-specific multifluor FISH analysis allows physical characterization of complex chromosome abnormalities in neoplasia.
Genes, chromosomes & cancer 2000;28(3):347-52.
2000: David Gisselsson; L Pettersson; Mattias Höglund; Markus Heidenblad; Ludmila Gorunova; Joop Wiegant; Fredrik Mertens; Paola Dal Cin; Felix Mitelman; Nils Mandahl
Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5357-62.
2000: Luis A Parada; Janusz Limon; Mariola Iliszko; Piotr Czauderna; David Gisselsson; Mattias Höglund; Carl-Magnus Kullendorff; Thomas Wiebe; Fredrik Mertens; Bertil Johansson
Cytogenetics of hepatoblastoma: further characterization of 1q rearrangements by fluorescence in situ hybridization: an international collaborative study.
Medical and pediatric oncology 2000;34(3):165-70.
2000: Fredrik Mertens; Marcelo L Larramendy; Anita Gustavsson; David Gisselsson; Anders Rydholm; Otte Brosjö; Felix Mitelman; Sakari Knuutila; Nils Mandahl
Radiation-associated sarcomas are characterized by complex karyotypes with frequent rearrangements of chromosome arm 3p.
Cancer genetics and cytogenetics 2000;116(2):89-96.
1999: David Gisselsson; Henryk A Domanski; Mattias Höglund; Birgitta Carlén; Fredrik Mertens; Helena Willén; Nils Mandahl
Unique cytological features and chromosome aberrations in chondroid lipoma: a case report based on fine-needle aspiration cytology, histopathology, electron microscopy, chromosome banding, and molecular cytogenetics.
The American journal of surgical pathology 1999;23(10):1300-4.
1999: David Gisselsson; Mattias Höglund; Fredrik Mertens; Nils Mandahl
Variable stability of chromosomes containing amplified alpha-satellite sequences in human mesenchymal tumours.
Chromosoma 1999;108(5):271-7.
1999: David Gisselsson; Mattias Höglund; Fredrik Mertens; B Johansson; Paola Dal Cin; Herman Van Den Berghe; W C Earnshaw; Felix Mitelman; Nils Mandahl
The structure and dynamics of ring chromosomes in human neoplastic and non-neoplastic cells.
Human genetics 1999;104(4):315-25.
1998: David Gisselsson; P Andreasson; Jeanne M Meis-Kindblom; Lars-Gunnar Kindblom; Fredrik Mertens; Nils Mandahl
Amplification of 12q13 and 12q15 sequences in a sclerosing epithelioid fibrosarcoma.
Cancer genetics and cytogenetics 1998;107(2):102-6.
1998: David Gisselsson; Mattias Höglund; Kevin P O'Brien; Jan P Dumanski; Fredrik Mertens; Nils Mandahl
A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences.
Cancer letters 1998;133(2):129-34.
1998: David Gisselsson; Mattias Höglund; Fredrik Mertens; Felix Mitelman; Nils Mandahl
Chromosomal organization of amplified chromosome 12 sequences in mesenchymal tumors detected by fluorescence in situ hybridization.
Genes, chromosomes & cancer 1998;23(3):203-12.