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Candece Gladson

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Qiang Ding; Haotian Fang; Candece L Gladson; Lisa M Grove; Haurko Hayasaka; Meng Hu; S Ohidar Rahaman; Brian D Southern; Qinjiu Tang; Hongju Wu; Youfeng Yang; Zhiying You; Anni Zheng; Guo-Qiang Cai; Mitchell A Olman
FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis.
Justin D Lathia; Emily Levy; Meizhang Li; Roger E McLendon; Ichiro Nakano; Heidi S Phillips; M R Sandhya Rani; Eunnyung Bae; Shideng Bao; Markus Bredel; Lin Cheng; Joseph Gallagher; Candece L Gladson; Hacer Guvenc; James S Hale; Peter E Hall; Anita B Hjelmeland; Ping Huang; Albert Lai; Julia Selfridge; Andrew E Sloan; Monica Venere; Qiulian Wu; Jeremy N Rich
Laminin alpha 2 enables glioblastoma stem cell growth.
Lizbeth Robles Irizarry; Candece L Gladson; Dolores Hambardzumyan; Ichiro Nakano; Manmeet S Ahluwalia
Therapeutic targeting of VEGF in the treatment of glioblastoma.

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All Publications

2013: Qiang Ding; Haotian Fang; Candece L Gladson; Lisa M Grove; Haurko Hayasaka; Meng Hu; S Ohidar Rahaman; Brian D Southern; Qinjiu Tang; Hongju Wu; Youfeng Yang; Zhiying You; Anni Zheng; Guo-Qiang Cai; Mitchell A Olman
FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis.
The American journal of pathology 2013;182(5):1572-84.
2012: Justin D Lathia; Emily Levy; Meizhang Li; Roger E McLendon; Ichiro Nakano; Heidi S Phillips; M R Sandhya Rani; Eunnyung Bae; Shideng Bao; Markus Bredel; Lin Cheng; Joseph Gallagher; Candece L Gladson; Hacer Guvenc; James S Hale; Peter E Hall; Anita B Hjelmeland; Ping Huang; Albert Lai; Julia Selfridge; Andrew E Sloan; Monica Venere; Qiulian Wu; Jeremy N Rich
Laminin alpha 2 enables glioblastoma stem cell growth.
Annals of neurology 2012;72(5):766-78.
2012: Lizbeth Robles Irizarry; Candece L Gladson; Dolores Hambardzumyan; Ichiro Nakano; Manmeet S Ahluwalia
Therapeutic targeting of VEGF in the treatment of glioblastoma.
Expert opinion on therapeutic targets 2012;16(10):973-84.
2012: Ping Huang; Justin D Lathia; Amy S Nowacki; Richard A Prayson; M R Sandhya Rani; Jeremy N Rich; Andrew E Sloan; Russell Tipps; Robert J Weil; Manmeet S Ahluwalia; Eunnyung Bae; Hirad Hedayat; Candece L Gladson
Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma.
Cancer research 2012;72(6):1428-37.
2011: Dongyan Wang; Mitchell A Olman; Jerry Stewart; Russell Tipps; Ping Huang; Paul W Sanders; Eric Toline; Richard A Prayson; Jeongwu Lee; Cheryl A Palmer; G Yancey Gillespie; Wei Michael Liu; Russell O Pieper; Jun-Lin Guan; Robert J Weil; Candece L Gladson
Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.
PloS one 2011;6(5):e19629.
2010: Manmeet S Ahluwalia; John de Groot; Wei Michael Liu; Candece L Gladson
Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studies.
Cancer letters 2010;298(2):139-49.
2010: Guo-qiang Cai; Anni Zheng; Qingjiu Tang; Eric White; Chu-Fang Chou; Candece L Gladson; Mitchell A Olman; Qiang Ding
Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts.
Experimental cell research 2010;316(9):1600-9.
2010: Philip A Klenotic; Ping Huang; Juan Palomo; Balveen Kaur; Erwin Van Meir; Michael A Vogelbaum; Maria Febbraio; Candece L Gladson; Roy L Silverstein
Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin.
The American journal of pathology 2010;176(4):2039-50.
2010: L Burt Nabors; John B Fiveash; James M Markert; Manasi S Kekan; George Y Gillespie; Zhi Huang; Martin J Johnson; Sreelatha Meleth; Huichien Kuo; Candece L Gladson; Hassan M Fathallah-Shaykh
A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.
Archives of neurology 2010;67(3):313-9.
2010: Manmeet S Ahluwalia; Candece L Gladson
Progress on antiangiogenic therapy for patients with malignant glioma.
Journal of oncology 2010;2010():689018.
2010: Candece L Gladson; Richard A Prayson; Wei Michael Liu
The pathobiology of glioma tumors.
Annual review of pathology 2010;5():33-50.
2009: Braden C McFarland; Jerry Stewart; Amal Hamza; Robert Nordal; Donald J Davidson; Jack Henkin; Candece L Gladson
Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.
Cancer research 2009;69(13):5537-45.
2009: Sha Zhu; Candece L Gladson; Kimberly E White; Qiang Ding; Jerry Stewart; Tong H Jin; Harold A Chapman; Mitchell A Olman
Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins.
American journal of physiology. Lung cellular and molecular physiology 2009;297(1):L97-108.
2009: Tanya A Rege; Jerry Stewart; Brian Dranka; Etty N Benveniste; Roy L Silverstein; Candece L Gladson
Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1.
Journal of cellular physiology 2009;218(1):94-103.
2008: Candece L Gladson; Danny R Welch
New insights into the role of CXCR4 in prostate cancer metastasis.
Cancer biology & therapy 2008;7(11):1849-51.
2008: Qiang Ding; Candece L Gladson; Hongju Wu; Haurko Hayasaka; Mitchell A Olman
Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner.
The Journal of biological chemistry 2008;283(40):26839-49.
2008: Joshua C Anderson; Braden C McFarland; Candece L Gladson
New molecular targets in angiogenic vessels of glioblastoma tumours.
Expert reviews in molecular medicine 2008;10():e23.
2007: Joshua C Anderson; J Robert Grammer; Wenquan Wang; L Burt Nabors; Jack Henkin; Jerry E Stewart; Candece L Gladson
ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis.
Cancer biology & therapy 2007;6(3):454-62.
2006: Braden D Cox; Meera Natarajan; Michelle R Stettner; Candece L Gladson
New concepts regarding focal adhesion kinase promotion of cell migration and proliferation.
Journal of cellular biochemistry 2006;99(1):35-52.
2006: N Shastry Akella; Qiang Ding; Ingrid Menegazzo; Wenquan Wang; G Yancey Gillespie; J Robert Grammer; Candece L Gladson; L Burt Nabors
A novel technique to quantify glioma tumor invasion using serial microscopy sections.
Journal of neuroscience methods 2006;153(2):183-9.
2006: Constance Y Fears; Candece L Gladson; Anne Woods
Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells.
The Journal of biological chemistry 2006;281(21):14533-6.
2006: Meera Natarajan; Jerry E Stewart; Erica A Golemis; Elena N Pugacheva; K Alexandropoulos; B D Cox; Wenquan Wang; J Robert Grammer; Candece L Gladson
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells.
Oncogene 2006;25(12):1721-32.
2005: Constance Y Fears; J Robert Grammer; Jerry E Stewart; Douglas S Annis; Deane F Mosher; Paul Bornstein; Candece L Gladson
Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model.
Cancer research 2005;65(20):9338-46.
2005: Dongyan Wang; Joshua C Anderson; Candece L Gladson
The role of the extracellular matrix in angiogenesis in malignant glioma tumors.
Brain pathology (Zurich, Switzerland) 2005;15(4):318-26.
2005: Wook Joon Chung; Susan Lyons; Gina M Nelson; Hashir Hamza; Candece L Gladson; G Yancey Gillespie; Harald Sontheimer
Inhibition of cystine uptake disrupts the growth of primary brain tumors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(31):7101-10.
2005: Michelle R Stettner; Wenquan Wang; L Burt Nabors; Suman Bharara; Daniel C Flynn; J Robert Grammer; G Yancey Gillespie; Candece L Gladson
Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells.
Cancer research 2005;65(13):5535-43.
2005: Tanya A Rege; Constance Y Fears; Candece L Gladson
Endogenous inhibitors of angiogenesis in malignant gliomas: nature's antiangiogenic therapy.
Neuro-oncology 2005;7(2):106-21.
2005: Qiang Ding; J Robert Grammer; Mark A Nelson; Jun-Lin Guan; Jerry E Stewart; Candece L Gladson
p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain.
The Journal of biological chemistry 2005;280(8):6802-15.
2004: Constance Y Fears; Harald Sontheimer; Daniel C Bullard; Candece L Gladson
Could labeled neuronal progenitor cells be used to target glioma tumor endothelium?
Cancer biology & therapy 2004;3(9):845-6.
2004: Eben Rosenthal; Allison McCrory; Melissa Talbert; Geoff Young; Joanne E Murphy-Ullrich; Candece L Gladson
Elevated expression of TGF-beta1 in head and neck cancer-associated fibroblasts.
Molecular carcinogenesis 2004;40(2):116-21.
2004: Timothy P Hecker; Qiang Ding; Tanya A Rege; Steven K Hanks; Candece L Gladson
Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells.
Oncogene 2004;23(22):3962-71.
2004: Matthew Derrick; Ning Ling Luo; Joanne C Bregman; Tamas Jilling; Xinhai Ji; Kara Fisher; Candece L Gladson; Douglas J Beardsley; Geoffrey Murdoch; Stephen A Back; Sidhartha Tan
Preterm fetal hypoxia-ischemia causes hypertonia and motor deficits in the neonatal rabbit: a model for human cerebral palsy?
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(1):24-34.
2003: Pavle Repovic; Constance Y Fears; Candece L Gladson; Etty N Benveniste
Oncostatin-M induction of vascular endothelial growth factor expression in astroglioma cells.
Oncogene 2003;22(50):8117-24.
2003: Qiang Ding; Jerry Stewart; Mitchell A Olman; Michelle R Klobe; Candece L Gladson
The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged.
The Journal of biological chemistry 2003;278(41):39882-91.
2003: Eben Rosenthal; Satya Shreenivas; Glenn E Peters; William E Grizzle; Renee A Desmond; Candece L Gladson
Expression of extracellular matrix metalloprotease inducer in laryngeal squamous cell carcinoma.
The Laryngoscope 2003;113(8):1406-10.
2003: Henry Haskell; Meera Natarajan; Timothy P Hecker; Qiang Ding; Jerry Stewart; J Robert Grammer; Candece L Gladson
Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2157-65.
2003: Timothy P Hecker; Candece L Gladson
Focal adhesion kinase in cancer.
Frontiers in bioscience : a journal and virtual library 2003;8():s705-14.
2003: Meera Natarajan; Timothy P Hecker; Candece L Gladson
FAK signaling in anaplastic astrocytoma and glioblastoma tumors.
Cancer journal (Sudbury, Mass.) 2003;9(2):126-33.
2002: Qiang Ding; Jerry Stewart; Charles W Prince; Pi-Ling Chang; Mohit Trikha; Xiaosi Han; J Robert Grammer; Candece L Gladson
Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: differences in integrin signaling during cell adhesion to osteopontin versus vitronectin.
Cancer research 2002;62(18):5336-43.
2002: Timothy P Hecker; J Robert Grammer; G Yancey Gillespie; Jerry Stewart; Candece L Gladson
Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples.
Cancer research 2002;62(9):2699-707.
2002: Sha Zhu; Candece L Gladson; Jerry Stewart; Kimberly E White; Harold A Chapman; Mitchell A Olman
Adenovirally mediated expression of urokinase receptor binding site on integrin alpha-chain blocks adhesion and migration of human lung fibroblasts.
Chest 2002;121(3 Suppl):34S-35S.
2001: X Han; Jerry E Stewart; Susan L Bellis; Etty N Benveniste; Qiang Ding; K Tachibana; J Robert Grammer; Candece L Gladson
TGF-beta1 up-regulates paxillin protein expression in malignant astrocytoma cells: requirement for a fibronectin substrate.
Oncogene 2001;20(55):7976-86.
2001: Albert J Wong; M Padarathsingh; D N Louis; Sandra Rempel; S Ladisch; Candece L Gladson
New approaches to the molecular biology, classification, and therapy of nervous system tumors: a workshop of the National Institutes of Health Pathology B study section.
The American journal of pathology 2001;159(5):1971-4.
2000: D Wang; J Robert Grammer; Charles S Cobbs; Jerry E Stewart; Zhiyong Liu; R Rhoden; Timothy P Hecker; Qiang Ding; Candece L Gladson
p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo.
Journal of cell science 2000;113 Pt 23():4221-30.
2000: Dan Wang; S Yamamoto; N Hijiya; Etty N Benveniste; Candece L Gladson
Transcriptional regulation of the human osteopontin promoter: functional analysis and DNA-protein interactions.
Oncogene 2000;19(50):5801-9.
2000: Candece L Gladson; Jerry E Stewart; Mitchell A Olman; Pi-Ling Chang; L M Schnapp; J Robert Grammer; Etty N Benveniste
Attachment of primary neonatal rat astrocytes to vitronectin is mediated by integrins alphavbeta5 and alpha8beta1: modulation by the type 1 plasminogen activator inhibitor.
Neuroscience letters 2000;283(2):157-61.
2000: Q Ding; Candece L Gladson; Clyde Guidry; S A Santoro; S Kent Dickeson; J T Shin; John A Thompson
Extracellular FGF-1 inhibits cytoskeletal organization and promotes fibroblast motility.
Growth factors (Chur, Switzerland) 2000;18(2):93-107.
1999: Candece L Gladson
The extracellular matrix of gliomas: modulation of cell function.
Journal of neuropathology and experimental neurology 1999;58(10):1029-40.
1999: Sidhartha Tan; F Zhou; Vance G Nielsen; Z Wang; Candece L Gladson; Dale A Parks
Increased injury following intermittent fetal hypoxia-reoxygenation is associated with increased free radical production in fetal rabbit brain.
Journal of neuropathology and experimental neurology 1999;58(9):972-81.
1999: J Ling; Zhiyong Liu; D Wang; Candece L Gladson
Malignant astrocytoma cell attachment and migration to various matrix proteins is differentially sensitive to phosphoinositide 3-OH kinase inhibitors.
Journal of cellular biochemistry 1999;73(4):533-44.
1999: V Pijuan-Thompson; J Robert Grammer; Jerry Stewart; Roy L Silverstein; SF Pearce; G P Tuszynski; Joanne E Murphy-Ullrich; Candece L Gladson
Retinoic acid alters the mechanism of attachment of malignant astrocytoma and neuroblastoma cells to thrombospondin-1.
Experimental cell research 1999;249(1):86-101.
1999: G Yancey Gillespie; Liliana Soroceanu; TJ Manning; Candece L Gladson; Steven S Rosenfeld
Glioma migration can be blocked by nontoxic inhibitors of myosin II.
Cancer research 1999;59(9):2076-82.
1999: Candece L Gladson; A Guha; A J Wong
1998 Neurotumor Club. March 30, 1998, New Orleans, La.
Neuro-oncology 1999;1(1):30-2.
1999: R Jennelle; Candece L Gladson; C Palmer; B Guthrie; J Markert
Paradoxical labeling of radiosurgically treated quiescent tumors with Ki67, a marker of cellular proliferation.
Stereotactic and functional neurosurgery 1999;72 Suppl 1():45-52.
1998: Sidhartha Tan; F Zhou; Vance G Nielsen; Z Wang; Candece L Gladson; Dale A Parks
Sustained hypoxia-ischemia results in reactive nitrogen and oxygen species production and injury in the premature fetal rabbit brain.
Journal of neuropathology and experimental neurology 1998;57(6):544-53.
1997: Candece L Gladson; C Dennis; Thomas C Rotolo; David R Kelly; J Robert Grammer
Vitronectin expression in differentiating neuroblastic tumors: integrin alpha v beta 5 mediates vitronectin-dependent adhesion of retinoic-acid-differentiated neuroblastoma cells.
The American journal of pathology 1997;150(5):1631-46.
1997: V Pijuan-Thompson; Candece L Gladson
Ligation of integrin alpha5beta1 is required for internalization of vitronectin by integrin alphavbeta3.
The Journal of biological chemistry 1997;272(5):2736-43.
1996: Candece L Gladson
Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors.
Journal of neuropathology and experimental neurology 1996;55(11):1143-9.
1996: Candece L Gladson; S Hancock; M M Arnold; O M Faye-Petersen; R P Castleberry; D R Kelly
Stage-specific expression of integrin alphaVbeta3 in neuroblastic tumors.
The American journal of pathology 1996;148(5):1423-34.
1995: Mitchell A Olman; Nigel Mackman; Candece L Gladson; KM Moser; David J Loskutoff
Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse.
The Journal of clinical investigation 1995;96(3):1621-30.
1995: Candece L Gladson; V Pijuan-Thompson; Mitchell A Olman; G Yancey Gillespie; I Z Yacoub
Up-regulation of urokinase and urokinase receptor genes in malignant astrocytoma.
The American journal of pathology 1995;146(5):1150-60.
1995: Candece L Gladson; Josiah N Wilcox; L Sanders; G Yancey Gillespie; D A Cheresh
Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors.
Journal of cell science 1995;108 ( Pt 3)():947-56.
1995: Raj K Singh; Robert W Hardy; M H Wang; Jodie Williford; Candece L Gladson; Jay M McDonald; G P Siegal
Stearate inhibits human tumor cell invasion.
Invasion & metastasis 1995;15(3-4):144-55.