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Mark Gladwin

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Minniti Caterina P; Machado Roberto F; Coles Wynona A; Sachdev Vandana; Gladwin Mark T; Kato Gregory J
Endothelin receptor antagonists for pulmonary hypertension in adult patients with sickle cell disease.
Gladwin Mark T; Kim-Shapiro Daniel B
Storage lesion in banked blood due to hemolysis-dependent disruption of nitric oxide homeostasis.
Campbell Andrew; Minniti Caterina P; Nouraie Mehdi; Arteta Manuel; Rana Sohail; Onyekwere Onyinye; Sable Craig; Ensing Gregory; Dham Niti; Luchtman-Jones Lori; Kato Gregory J; Gladwin Mark T; Castro Oswaldo L; Gordeuk Victor R
Prospective evaluation of haemoglobin oxygen saturation at rest and after exercise in paediatric sickle cell disease patients.

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All Publications

2009: Minniti Caterina P; Machado Roberto F; Coles Wynona A; Sachdev Vandana; Gladwin Mark T; Kato Gregory J
Endothelin receptor antagonists for pulmonary hypertension in adult patients with sickle cell disease.
British journal of haematology 2009;147(5):737-43.
2009: Gladwin Mark T; Kim-Shapiro Daniel B
Storage lesion in banked blood due to hemolysis-dependent disruption of nitric oxide homeostasis.
Current opinion in hematology 2009;16(6):515-23.
2009: Campbell Andrew; Minniti Caterina P; Nouraie Mehdi; Arteta Manuel; Rana Sohail; Onyekwere Onyinye; Sable Craig; Ensing Gregory; Dham Niti; Luchtman-Jones Lori; Kato Gregory J; Gladwin Mark T; Castro Oswaldo L; Gordeuk Victor R
Prospective evaluation of haemoglobin oxygen saturation at rest and after exercise in paediatric sickle cell disease patients.
British journal of haematology 2009;147(3):352-9.
2009: Dezfulian Cameron; Shiva Sruti; Alekseyenko Aleksey; Pendyal Akshay; Beiser D G; Munasinghe Jeeva P; Anderson Stasia A; Chesley Christopher F; Vanden Hoek T L; Gladwin Mark T
Nitrite therapy after cardiac arrest reduces reactive oxygen species generation, improves cardiac and neurological function, and enhances survival via reversible inhibition of mitochondrial complex I.
Circulation 2009;120(10):897-905.
2009: Dham Niti; Ensing Gregory; Minniti Caterina; Campbell Andrew; Arteta Manuel; Rana Sohail; Darbari Deepika; Nouraie Mehdi; Onyekwere Onyinye; Lasota Malgorzata; Kato Gregory J; Gladwin Mark T; Castro Oswaldo; Gordeuk Victor; Sable Craig
Prospective echocardiography assessment of pulmonary hypertension and its potential etiologies in children with sickle cell disease.
The American journal of cardiology 2009;104(5):713-20.
2009: Kato Gregory J; Hebbel Robert P; Steinberg Martin H; Gladwin Mark T
Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions.
American journal of hematology 2009;84(9):618-25.
2009: Bivalacqua Trinity J; Musicki Biljana; Hsu Lewis L; Gladwin Mark T; Burnett Arthur L; Champion Hunter C
Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism.
The journal of sexual medicine 2009;6(9):2494-504.
2009: Raat Nicolaas J H; Noguchi Audrey C; Liu Virginia B; Raghavachari Nalini; Liu Delong; Xu Xiuli; Shiva Sruti; Munson Peter J; Gladwin Mark T
Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response.
Free radical biology & medicine 2009;47(5):510-7.
2009: van Faassen Ernst E; Bahrami Soheyl; Feelisch Martin; Hogg Neil; Kelm Malte; Kim-Shapiro Daniel B; Kozlov Andrey V; Li Haitao; Lundberg Jon O; Mason Ron; Nohl Hans; Rassaf Tienush; Samouilov Alexandre; Slama-Schwok Anny; Shiva Sruti; Vanin Anatoly F; Weitzberg Eddie; Zweier Jay; Gladwin Mark T
Nitrite as regulator of hypoxic signaling in mammalian physiology.
Medicinal research reviews 2009;29(5):683-741.
2009: Williams Kirsten M; Chien Jason W; Gladwin Mark T; Pavletic Steven Z
Bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation.
JAMA : the journal of the American Medical Association 2009;302(3):306-14.
2009: Pellegrino Daniela; Shiva Sruti; Angelone Tommaso; Gladwin Mark T; Tota Bruno
Nitrite exerts potent negative inotropy in the isolated heart via eNOS-independent nitric oxide generation and cGMP-PKG pathway activation.
Biochimica et biophysica acta 2009;1787(7):818-27.
2009: Simonneau Gérald; Robbins Ivan M; Beghetti Maurice; Channick Richard N; Delcroix Marion; Denton Christopher P; Elliott C Gregory; Gaine Sean P; Gladwin Mark T; Jing Zhi-Cheng; Krowka Michael J; Langleben David; Nakanishi Norifumi; Souza Rogério
Updated clinical classification of pulmonary hypertension.
Journal of the American College of Cardiology 2009;54(1 Suppl):S43-54.
2009: Gladwin Mark T; Shiva Sruti
The ligand binding battle at cytochrome c oxidase: how NO regulates oxygen gradients in tissue.
Circulation research 2009;104(10):1136-8.
2009: Raat N J H; Shiva S; Gladwin M T
Effects of nitrite on modulating ROS generation following ischemia and reperfusion.
Advanced drug delivery reviews 2009;61(4):339-50.
2009: Little Jane A; Hauser Kristine Partovi; Martyr Sabrina E; Harris Amy; Maric Irina; Morris Claudia R; Suh Jung H; Taylor James; Castro Oswaldo; Machado Roberto; Kato Gregory; Gladwin Mark T
Hematologic, biochemical, and cardiopulmonary effects of L-arginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy.
European journal of haematology 2009;82(4):315-21.
2009: Shiva Sruti; Gladwin Mark T
Nitrite mediates cytoprotection after ischemia/reperfusion by modulating mitochondrial function.
Basic research in cardiology 2009;104(2):113-9.
2009: Minniti Caterina P; Sable Craig; Campbell Andrew; Rana Sohail; Ensing Gregory; Dham Niti; Onyekwere Onyinye; Nouraie Mehdi; Kato Gregory J; Gladwin Mark T; Castro Oswaldo L; Gordeuk Victor R
Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation.
Haematologica 2009;94(3):340-7.
2009: Blood Arlin B; Tiso Mauro; Verma Shilpa T; Lo Jennifer; Joshi Mahesh S; Azarov Ivan; Longo Lawrence D; Gladwin Mark T; Kim-Shapiro Daniel B; Power Gordon G
Increased nitrite reductase activity of fetal versus adult ovine hemoglobin.
American journal of physiology. Heart and circulatory physiology 2009;296(2):H237-46.
2009: Gladwin Mark T; Grubina Rozalina; Doyle Michael P
The new chemical biology of nitrite reactions with hemoglobin: R-state catalysis, oxidative denitrosylation, and nitrite reductase/anhydrase.
Accounts of chemical research 2009;42(1):157-67.
2009: Raghavachari Nalini; Xu Xiuli; Munson Peter J; Gladwin Mark T
Characterization of whole blood gene expression profiles as a sequel to globin mRNA reduction in patients with sickle cell disease.
PloS one 2009;4(8):e6484.
2008: Kato Gregory J; Gladwin Mark T
Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy.
JAMA : the journal of the American Medical Association 2008;300(22):2638-46.
2008: Gladwin Mark T; Vichinsky Elliott
Pulmonary complications of sickle cell disease.
The New England journal of medicine 2008;359(21):2254-65.
2008: Morris Claudia R; Gladwin Mark T; Kato Gregory J
Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders.
Current molecular medicine 2008;8(7):620-32.
2008: Basu Swati; Azarova Natalia A; Font Michael D; King S Bruce; Hogg Neil; Gladwin Mark T; Shiva Sruti; Kim-Shapiro Daniel B
Nitrite reductase activity of cytochrome c.
The Journal of biological chemistry 2008;283(47):32590-7.
2008: Gladwin Mark T; Kim-Shapiro Daniel B
The functional nitrite reductase activity of the heme-globins.
Blood 2008;112(7):2636-47.
2008: Mack A Kyle; McGowan Ii Vicki R; Tremonti Carole K; Ackah Diana; Barnett Christopher; Machado Roberto F; Gladwin Mark T; Kato Gregory J
Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study.
British journal of haematology 2008;142(6):971-8.
2008: Minneci Peter C; Deans Katherine J; Shiva Sruti; Zhi Huang; Banks Steven M; Kern Steven; Natanson Charles; Solomon Steven B; Gladwin Mark T
Nitrite reductase activity of hemoglobin as a systemic nitric oxide generator mechanism to detoxify plasma hemoglobin produced during hemolysis.
American journal of physiology. Heart and circulatory physiology 2008;295(2):H743-54.
2008: Sinha Shashank S; Shiva Sruti; Gladwin Mark T
Myocardial protection by nitrite: evidence that this reperfusion therapeutic will not be lost in translation.
Trends in cardiovascular medicine 2008;18(5):163-72.
2008: Hendgen-Cotta Ulrike B; Merx Marc W; Shiva Sruti; Schmitz Joel; Becher Stefanie; Klare Johann P; Steinhoff Heinz-Jürgen; Goedecke Axel; Schrader Jürgen; Gladwin Mark T; Kelm Malte; Rassaf Tienush
Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):10256-61.
2008: Krajewski Megan L; Hsu Lewis L; Gladwin Mark T
The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology.
American journal of physiology. Heart and circulatory physiology 2008;295(1):H4-7.
2008: Gonzalez Felix M; Shiva Sruti; Vincent Pamela S; Ringwood Lorna A; Hsu Li-Yueh; Hon Yuen Yi; Aletras Anthony H; Cannon Richard O; Gladwin Mark T; Arai Andrew E
Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction.
Circulation 2008;117(23):2986-94.
2008: Aliyu Zakari Y; Gordeuk Victor; Sachdev Vandana; Babadoko Aliyu; Mamman Aisha I; Akpanpe Peter; Attah Ester; Suleiman Yusuf; Aliyu Nurudeen; Yusuf Jamilu; Mendelsohn Laurel; Kato Gregory J; Gladwin Mark T
Prevalence and risk factors for pulmonary artery systolic hypertension among sickle cell disease patients in Nigeria.
American journal of hematology 2008;83(6):485-90.
2008: Wood Katherine C; Hsu Lewis L; Gladwin Mark T
Sickle cell disease vasculopathy: a state of nitric oxide resistance.
Free radical biology & medicine 2008;44(8):1506-28.
2008: He Xiaojun; Azarov Ivan; Jeffers Anne; Presley Tennille; Richardson Jodi; King S Bruce; Gladwin Mark T; Kim-Shapiro Daniel B
The potential of Angeli's salt to decrease nitric oxide scavenging by plasma hemoglobin.
Free radical biology & medicine 2008;44(7):1420-32.
2008: Wang Xunde; Kettenhofen Nicholas J; Shiva Sruti; Hogg Neil; Gladwin Mark T
Copper dependence of the biotin switch assay: modified assay for measuring cellular and blood nitrosated proteins.
Free radical biology & medicine 2008;44(7):1362-72.
2008: Gladwin Mark T
Evidence mounts that nitrite contributes to hypoxic vasodilation in the human circulation.
Circulation 2008;117(5):594-7.
2008: Gladwin Mark T; Patel Rakesh P
The role of red blood cells and hemoglobin-nitric oxide interactions on blood flow.
American journal of respiratory cell and molecular biology 2008;38(2):125-6.
2008: Lundberg Jon O; Weitzberg Eddie; Gladwin Mark T
The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics.
Nature reviews. Drug discovery 2008;7(2):156-67.
2008: Grubina Rozalina; Basu Swati; Tiso Mauro; Kim-Shapiro Daniel B; Gladwin Mark T
Nitrite reductase activity of hemoglobin S (sickle) provides insight into contributions of heme redox potential versus ligand affinity.
The Journal of biological chemistry 2008;283(6):3628-38.
2008: Gladwin Mark T; Kato Gregory J
Hemolysis-associated hypercoagulability in sickle cell disease: the plot (and blood) thickens!
Haematologica 2008;93(1):1-3.
2008: Aliyu Zakari Y; Kato Gregory J; Taylor James; Babadoko Aliyu; Mamman Aisha I; Gordeuk Victor R; Gladwin Mark T
Sickle cell disease and pulmonary hypertension in Africa: a global perspective and review of epidemiology, pathophysiology, and management.
American journal of hematology 2008;83(1):63-70.
2008: Taylor James G; Woods Gerald M; Machado Roberto; Kato Gregory J; Gladwin Mark T
Severe pulmonary hypertension in an adolescent with sickle cell disease.
American journal of hematology 2008;83(1):71-2.
2008: Taylor James G; Ackah Diana; Cobb Crystal; Orr Nick; Percy Melanie J; Sachdev Vandana; Machado Roberto; Castro Oswaldo; Kato Gregory J; Chanock Stephen J; Gladwin Mark T
Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease.
American journal of hematology 2008;83(1):6-14.
2008: Gordeuk Victor R; Sachdev Vandana; Taylor James G; Gladwin Mark T; Kato Gregory; Castro Oswaldo L
Relative systemic hypertension in patients with sickle cell disease is associated with risk of pulmonary hypertension and renal insufficiency.
American journal of hematology 2008;83(1):15-8.
2008: Linguraru Marius George; Orandi Babak J; Van Uitert Robert L; Mukherjee Nisha; Summers Ronald M; Gladwin Mark T; Machado Roberto F; Wood Bradford J
CT and image processing non-invasive indicators of sickle cell secondary pulmonary hypertension.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2008;2008():859-62.
2008: Kettenhofen Nicholas J; Wang Xunde; Gladwin Mark T; Hogg Neil
In-gel detection of S-nitrosated proteins using fluorescence methods.
Methods in enzymology 2008;441():53-71.
2008: Taylor James G; Nolan Vikki G; Mendelsohn Laurel; Kato Gregory J; Gladwin Mark T; Steinberg Martin H
Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain.
PloS one 2008;3(5):e2095.
2008: Basu Swati; Wang Xunde; Gladwin Mark T; Kim-Shapiro Daniel B
Chemiluminescent detection of S-nitrosated proteins: comparison of tri-iodide, copper/CO/cysteine, and modified copper/cysteine methods.
Methods in enzymology 2008;440():137-56.
2007: Basu Swati; Grubina Rozalina; Huang Jinming; Conradie Jeanet; Huang Zhi; Jeffers Anne; Jiang Alice; He Xiaojun; Azarov Ivan; Seibert Ryan; Mehta Atul; Patel Rakesh; King Stephen Bruce; Hogg Neil; Ghosh Abhik; Gladwin Mark T; Kim-Shapiro Daniel B
Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin.
Nature chemical biology 2007;3(12):785-94.
2007: Dejam André; Hunter Christian J; Tremonti Carole; Pluta Ryszard M; Hon Yuen Yi; Grimes George; Partovi Kristine; Pelletier Mildred M; Oldfield Edward H; Cannon Richard O; Schechter Alan N; Gladwin Mark T
Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation.
Circulation 2007;116(16):1821-31.
2007: True Andrea L; Olive Michelle; Boehm Manfred; San Hong; Westrick Randal J; Raghavachari Nalini; Xu Xiuli; Lynn Edward G; Sack Michael N; Munson Peter J; Gladwin Mark T; Nabel Elizabeth G
Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.
Circulation research 2007;101(9):893-901.
2007: Isbell T Scott; Gladwin Mark T; Patel Rakesh P
Hemoglobin oxygen fractional saturation regulates nitrite-dependent vasodilation of aortic ring bioassays.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2565-72.
2007: Sebastiani Paola; Nolan Vikki G; Baldwin Clinton T; Abad-Grau Maria M; Wang Ling; Adewoye Adeboye H; McMahon Lillian C; Farrer Lindsay A; Taylor James G; Kato Gregory J; Gladwin Mark T; Steinberg Martin H
A network model to predict the risk of death in sickle cell disease.
Blood 2007;110(7):2727-35.
2007: Shiva Sruti; Sack Michael N; Greer James J; Duranski Mark; Ringwood Lorna A; Burwell Lindsay; Wang Xunde; MacArthur Peter H; Shoja Amir; Raghavachari Nalini; Calvert John W; Brookes Paul S; Lefer David J; Gladwin Mark T
Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer.
The Journal of experimental medicine 2007;204(9):2089-102.
2007: Villagra José; Shiva Sruti; Hunter Lori A; Machado Roberto F; Gladwin Mark T; Kato Gregory J
Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin.
Blood 2007;110(6):2166-72.
2007: Dezfulian Cameron; Raat Nicolaas; Shiva Sruti; Gladwin Mark T
Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics.
Cardiovascular research 2007;75(2):327-38.
2007: Wood Katherine C; Gladwin Mark T
The hydrogen highway to reperfusion therapy.
Nature medicine 2007;13(6):673-4.
2007: Anthi Anastasia; Machado Roberto F; Jison Maria L; Taveira-Dasilva Angelo M; Rubin Lewis J; Hunter Lori; Hunter Christian J; Coles Wynona; Nichols James; Avila Nilo A; Sachdev Vandana; Chen Clara C; Gladwin Mark T
Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension.
American journal of respiratory and critical care medicine 2007;175(12):1272-9.
2007: MacArthur Peter H; Shiva Sruti; Gladwin Mark T
Measurement of circulating nitrite and S-nitrosothiols by reductive chemiluminescence.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;851(1-2):93-105.
2007: Kato Gregory J; Onyekwere Onyinye C; Gladwin Mark T
Pulmonary hypertension in sickle cell disease: relevance to children.
Pediatric hematology and oncology 2007;24(3):159-70.
2007: Dejam André; Hunter Christian J; Gladwin Mark T
Effects of dietary nitrate on blood pressure.
The New England journal of medicine 2007;356(15):1590; author reply 1590.
2007: Grubina Rozalina; Huang Zhi; Shiva Sruti; Joshi Mahesh S; Azarov Ivan; Basu Swati; Ringwood Lorna A; Jiang Alice; Hogg Neil; Kim-Shapiro Daniel B; Gladwin Mark T
Concerted nitric oxide formation and release from the simultaneous reactions of nitrite with deoxy- and oxyhemoglobin.
The Journal of biological chemistry 2007;282(17):12916-27.
2007: Hsu Lewis L; Champion Hunter C; Campbell-Lee Sally A; Bivalacqua Trinity J; Manci Elizabeth A; Diwan Bhalchandra A; Schimel Daniel M; Cochard Audrey E; Wang Xunde; Schechter Alan N; Noguchi Constance T; Gladwin Mark T
Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.
Blood 2007;109(7):3088-98.
2007: Paul Jonathan D; Powell Tiffany M; Thompson Michael; Benjamin Moshe; Rodrigo Maria; Carlow Andrea; Annavajjhala Vidhya; Shiva Sruti; Dejam Andre; Gladwin Mark T; McCoy J Philip; Zalos Gloria; Press Beverly; Murphy Mandy; Hill Jonathan M; Csako Gyorgy; Waclawiw Myron A; Cannon Richard O
Endothelial progenitor cell mobilization and increased intravascular nitric oxide in patients undergoing cardiac rehabilitation.
Journal of cardiopulmonary rehabilitation and prevention 2007;27(2):65-73.
2007: Seam Nitin; Finkelstein Steven E; Gonzales Denise A; Schrump David S; Gladwin Mark T
The workup of stridor: virtual bronchoscopy as a complementary technique in the diagnosis of subglottic stenosis.
Respiratory care 2007;52(3):337-9.
2007: Raghavachari Nalini; Xu Xiuli; Harris Amy; Villagra Jose; Logun Carolea; Barb Jennifer; Solomon Michael A; Suffredini Anthony F; Danner Robert L; Kato Gregory; Munson Peter J; Morris Sidney M; Gladwin Mark T
Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease.
Circulation 2007;115(12):1551-62.
2007: Shiva Sruti; Huang Zhi; Grubina Rozalina; Sun Junhui; Ringwood Lorna A; MacArthur Peter H; Xu Xiuli; Murphy Elizabeth; Darley-Usmar Victor M; Gladwin Mark T
Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration.
Circulation research 2007;100(5):654-61.
2007: Sachdev Vandana; Machado Roberto F; Shizukuda Yukitaka; Rao Yesoda N; Sidenko Stanislav; Ernst Inez; St Peter Marilyn; Coles Wynona A; Rosing Douglas R; Blackwelder William C; Castro Oswaldo; Kato Gregory J; Gladwin Mark T
Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease.
Journal of the American College of Cardiology 2007;49(4):472-9.
2007: Machado Roberto F; Mack A Kyle; Martyr Sabrina; Barnett Christopher; Macarthur Peter; Sachdev Vandana; Ernst Inez; Hunter Lori A; Coles Wynona A; Nichols James P; Kato Gregory J; Gladwin Mark T
Severity of pulmonary hypertension during vaso-occlusive pain crisis and exercise in patients with sickle cell disease.
British journal of haematology 2007;136(2):319-25.
2007: Kato Gregory J; Gladwin Mark T; Steinberg Martin H
Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes.
Blood reviews 2007;21(1):37-47.
2006: Dias-Junior Carlos A C; Gladwin Mark T; Tanus-Santos Jose E
Low-dose intravenous nitrite improves hemodynamics in a canine model of acute pulmonary thromboembolism.
Free radical biology & medicine 2006;41(12):1764-70.
2006: Jeffers Anne; Gladwin Mark T; Kim-Shapiro Daniel B
Computation of plasma hemoglobin nitric oxide scavenging in hemolytic anemias.
Free radical biology & medicine 2006;41(10):1557-65.
2006: Gladwin Mark T; Raat Nicolaas J H; Shiva Sruti; Dezfulian Cameron; Hogg Neil; Kim-Shapiro Daniel B; Patel Rakesh P
Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation.
American journal of physiology. Heart and circulatory physiology 2006;291(5):H2026-35.
2006: Dezfulian Cameron; Raat Nicolaas J H; Gladwin Mark T
A pharmacogenomic study of atorvastatin effects on eNOS activity: do "statins" modulate blood nitrite levels and intravascular oxidant stress in susceptible individuals?
Free radical biology & medicine 2006;41(7):1041-3.
2006: Gladwin Mark T
Deconstructing endothelial dysfunction: soluble guanylyl cyclase oxidation and the NO resistance syndrome.
The Journal of clinical investigation 2006;116(9):2330-2.
2006: Shiva Sruti; Wang Xunde; Ringwood Lorna A; Xu Xueying; Yuditskaya Susan; Annavajjhala Vidhya; Miyajima Hiroaki; Hogg Neil; Harris Zena Leah; Gladwin Mark T
Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis.
Nature chemical biology 2006;2(9):486-93.
2006: Wang Xunde; Bryan Nathan S; MacArthur Peter H; Rodriguez Juan; Gladwin Mark T; Feelisch Martin
Measurement of nitric oxide levels in the red cell: validation of tri-iodide-based chemiluminescence with acid-sulfanilamide pretreatment.
The Journal of biological chemistry 2006;281(37):26994-7002.
2006: Little Jane A; McGowan Vicki R; Kato Gregory J; Partovi Kristine S; Feld Jordan J; Maric Irina; Martyr Sabrina; Taylor James G; Machado Roberto F; Heller Theo; Castro Oswaldo; Gladwin Mark T
Combination erythropoietin-hydroxyurea therapy in sickle cell disease: experience from the National Institutes of Health and a literature review.
Haematologica 2006;91(8):1076-83.
2006: Gladwin Mark T; Wang Xunde; Hogg Neil
Methodological vexation about thiol oxidation versus S-nitrosation -- a commentary on "An ascorbate-dependent artifact that interferes with the interpretation of the biotin-switch assay".
Free radical biology & medicine 2006;41(4):557-61.
2006: Pelletier Mildred M; Kleinbongard Petra; Ringwood Lorna; Hito Rania; Hunter Christian J; Schechter Alan N; Gladwin Mark T; Dejam André
The measurement of blood and plasma nitrite by chemiluminescence: pitfalls and solutions.
Free radical biology & medicine 2006;41(4):541-8.
2006: Holly M K; Dear J W; Hu X; Schechter A N; Gladwin M T; Hewitt S M; Yuen P S T; Star R A
Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure.
Kidney international 2006;70(3):496-506.
2006: Machado Roberto F; Anthi Anastasia; Steinberg Martin H; Bonds Duane; Sachdev Vandana; Kato Gregory J; Taveira-DaSilva Angelo M; Ballas Samir K; Blackwelder William; Xu Xiuli; Hunter Lori; Barton Bruce; Waclawiw Myron; Castro Oswaldo; Gladwin Mark T;
N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease.
JAMA : the journal of the American Medical Association 2006;296(3):310-8.
2006: Kato Gregory J; Hsieh Matthew; Machado Roberto; Taylor James; Little Jane; Butman John A; Lehky Tanya; Tisdale John; Gladwin Mark T
Cerebrovascular disease associated with sickle cell pulmonary hypertension.
American journal of hematology 2006;81(7):503-10.
2006: Hataishi Ryuji; Rodrigues Ana Clara; Neilan Tomas G; Morgan John G; Buys Emmanuel; Shiva Sruti; Tambouret Rosemary; Jassal Davinder S; Raher Michael J; Furutani Elissa; Ichinose Fumito; Gladwin Mark T; Rosenzweig Anthony; Zapol Warren M; Picard Michael H; Bloch Kenneth D; Scherrer-Crosbie Marielle
Inhaled nitric oxide decreases infarction size and improves left ventricular function in a murine model of myocardial ischemia-reperfusion injury.
American journal of physiology. Heart and circulatory physiology 2006;291(1):H379-84.
2006: Gladwin Mark T
Polycythemia, HIF-1alpha and pulmonary hypertension in Chuvash.
Haematologica 2006;91(6):722.
2006: Grubb Jessica R; Dejam André; Voell Jocelyn; Blackwelder William C; Sklar Peter A; Kovacs Joseph A; Cannon Richard O; Masur Henry; Gladwin Mark T
Lopinavir-ritonavir: effects on endothelial cell function in healthy subjects.
The Journal of infectious diseases 2006;193(11):1516-9.
2006: Kim-Shapiro Daniel B; Schechter Alan N; Gladwin Mark T
Unraveling the reactions of nitric oxide, nitrite, and hemoglobin in physiology and therapeutics.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):697-705.
2006: Kato Gregory J; McGowan Vicki; Machado Roberto F; Little Jane A; Taylor James; Morris Claudia R; Nichols James S; Wang Xunde; Poljakovic Mirjana; Morris Sidney M; Gladwin Mark T
Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease.
Blood 2006;107(6):2279-85.
2006: Crawford Jack H; Isbell T Scott; Huang Zhi; Shiva Sruti; Chacko Balu K; Schechter Alan N; Darley-Usmar Victor M; Kerby Jeffrey D; Lang John D; Kraus David; Ho Chien; Gladwin Mark T; Patel Rakesh P
Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation.
Blood 2006;107(2):566-74.
2006: Gladwin Mark T
Role of the red blood cell in nitric oxide homeostasis and hypoxic vasodilation.
Advances in experimental medicine and biology 2006;588():189-205.
2005: Minneci Peter C; Deans Katherine J; Zhi Huang; Yuen Peter S T; Star Robert A; Banks Steven M; Schechter Alan N; Natanson Charles; Gladwin Mark T; Solomon Steven B
Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin.
The Journal of clinical investigation 2005;115(12):3409-17.
2005: Piknova Barbora; Gladwin Mark T; Schechter Alan N; Hogg Neil
Electron paramagnetic resonance analysis of nitrosylhemoglobin in humans during NO inhalation.
The Journal of biological chemistry 2005;280(49):40583-8.
2005: Gladwin Mark T; Schechter Alan N; Kim-Shapiro Daniel B; Patel Rakesh P; Hogg Neil; Shiva Sruti; Cannon Richard O; Kelm Malte; Wink David A; Espey Michael Graham; Oldfield Edward H; Pluta Ryszard M; Freeman Bruce A; Lancaster Jack R; Feelisch Martin; Lundberg Jon O
The emerging biology of the nitrite anion.
Nature chemical biology 2005;1(6):308-14.
2005: Azarov Ivan; Huang Kris T; Basu Swati; Gladwin Mark T; Hogg Neil; Kim-Shapiro Daniel B
Nitric oxide scavenging by red blood cells as a function of hematocrit and oxygenation.
The Journal of biological chemistry 2005;280(47):39024-32.
2005: Gladwin Mark T
Nitrite as an intrinsic signaling molecule.
Nature chemical biology 2005;1(5):245-6.
2005: Castro Oswaldo; Gladwin Mark T
Pulmonary hypertension in sickle cell disease: mechanisms, diagnosis, and management.
Hematology/oncology clinics of North America 2005;19(5):881-96, vii.
2005: Castro Oswaldo; Gladwin Mark T; Kopterides Petros; Fremont Richard; Medoff Benjamin D
Case 17-2005: acute chest syndrome and ARDS.
The New England journal of medicine 2005;353(14):1529-30; author reply 1529-30.
2005: Kato Gregory J; Martyr Sabrina; Blackwelder William C; Nichols James S; Coles Wynona A; Hunter Lori A; Brennan Marie-Luise; Hazen Stanley L; Gladwin Mark T
Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality.
British journal of haematology 2005;130(6):943-53.
2005: Huang Kris T; Keszler Agnes; Patel Neil; Patel Rakesh P; Gladwin Mark T; Kim-Shapiro Daniel B; Hogg Neil
The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry.
The Journal of biological chemistry 2005;280(35):31126-31.
2005: Shiva Sruti; Gladwin Mark T
Nitrite therapeutics: back to the future.
Critical care medicine 2005;33(8):1865-7.
2005: Machado Roberto F; Martyr Sabrina; Kato Gregory J; Barst Robyn J; Anthi Anastasia; Robinson Michael R; Hunter Lori; Coles Wynona; Nichols James; Hunter Christian; Sachdev Vandana; Castro Oswaldo; Gladwin Mark T
Sildenafil therapy in patients with sickle cell disease and pulmonary hypertension.
British journal of haematology 2005;130(3):445-53.
2005: Huang Zhi; Shiva Sruti; Kim-Shapiro Daniel B; Patel Rakesh P; Ringwood Lorna A; Irby Cynthia E; Huang Kris T; Ho Chien; Hogg Neil; Schechter Alan N; Gladwin Mark T
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control.
The Journal of clinical investigation 2005;115(8):2099-107.
2005: Morris Claudia R; Kato Gregory J; Poljakovic Mirjana; Wang Xunde; Blackwelder William C; Sachdev Vandana; Hazen Stanley L; Vichinsky Elliott P; Morris Sidney M; Gladwin Mark T
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.
JAMA : the journal of the American Medical Association 2005;294(1):81-90.
2005: Dejam André; Hunter Christian J; Pelletier Mildred M; Hsu Lewis L; Machado Roberto F; Shiva Sruti; Power Gordon G; Kelm Malte; Gladwin Mark T; Schechter Alan N
Erythrocytes are the major intravascular storage sites of nitrite in human blood.
Blood 2005;106(2):734-9.
2005: Machado Roberto F; Gladwin Mark T
Chronic sickle cell lung disease: new insights into the diagnosis, pathogenesis and treatment of pulmonary hypertension.
British journal of haematology 2005;129(4):449-64.
2005: Duranski Mark R; Greer James J M; Dejam Andre; Jaganmohan Sathya; Hogg Neil; Langston William; Patel Rakesh P; Yet Shaw-Fang; Wang Xunde; Kevil Christopher G; Gladwin Mark T; Lefer David J
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver.
The Journal of clinical investigation 2005;115(5):1232-40.
2005: Gladwin Mark T
Hemoglobin as a nitrite reductase regulating red cell-dependent hypoxic vasodilation.
American journal of respiratory cell and molecular biology 2005;32(5):363-6.
2005: Lin Elaina E; Gladwin Mark T; Machado Roberto F
Pulmonary hypertension in patients with hemoglobinopathies: could a mechanism for dysfunction provide an avenue for novel therapeutics?
Haematologica 2005;90(4):441-4.
2005: Rother Russell P; Bell Leonard; Hillmen Peter; Gladwin Mark T
The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.
JAMA : the journal of the American Medical Association 2005;293(13):1653-62.
2005: Pluta Ryszard M; Dejam Andre; Grimes George; Gladwin Mark T; Oldfield Edward H
Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid hemorrhage.
JAMA : the journal of the American Medical Association 2005;293(12):1477-84.
2005: Lin Elaina E; Rodgers Griffin P; Gladwin Mark T
Hemolytic anemia-associated pulmonary hypertension in sickle cell disease.
Current hematology reports 2005;4(2):117-25.
2005: Swenson Kai E; Eveland Randy L; Gladwin Mark T; Swenson Erik R
Nitric oxide (NO) in normal and hypoxic vascular regulation of the spiny dogfish, Squalus acanthias.
Journal of experimental zoology. Part A, Comparative experimental biology 2005;303(2):154-60.
2005: Kim-Shapiro Daniel B; Gladwin Mark T; Patel Rakesh P; Hogg Neil
The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation.
Journal of inorganic biochemistry 2005;99(1):237-46.
2005: Gladwin Mark T; Kato Gregory J
Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2005;():51-7.
2004: Deem Steven; Kim Seong Su; Min Jin-Hye; Eveland Randy; Moulding Jennifer; Martyr Sabrina; Wang Xunde; Swenson Erik R; Gladwin Mark T
Pulmonary vascular effects of red blood cells containing S-nitrosated hemoglobin.
American journal of physiology. Heart and circulatory physiology 2004;287(6):H2561-8.
2004: Hunter Christian J; Dejam André; Blood Arlin B; Shields Howard; Kim-Shapiro Daniel B; Machado Roberto F; Tarekegn Selamawit; Mulla Neda; Hopper Andrew O; Schechter Alan N; Power Gordon G; Gladwin Mark T
Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator.
Nature medicine 2004;10(10):1122-7.
2004: Kim-Shapiro Daniel B; Patel Rakesh P; Schechter Alan N; Gladwin Mark T; Cannon Richard O; Hogg Neil
How do red blood cells dilate blood vessels?--Reply.
Circulation research 2004;95(3):e10.
2004: Wang Xunde; Tanus-Santos Jose E; Reiter Christopher D; Dejam Andre; Shiva Sruti; Smith Reginald D; Hogg Neil; Gladwin Mark T
Biological activity of nitric oxide in the plasmatic compartment.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(31):11477-82.
2004: Jison Maria L; Munson Peter J; Barb Jennifer J; Suffredini Anthony F; Talwar Shefali; Logun Carolea; Raghavachari Nalini; Beigel John H; Shelhamer James H; Danner Robert L; Gladwin Mark T
Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease.
Blood 2004;104(1):270-80.
2004: Dejam André; Hunter Christian J; Schechter Alan N; Gladwin Mark T
Emerging role of nitrite in human biology.
Blood cells, molecules & diseases 2004;32(3):423-9.
2004: Gladwin Mark T; Schechter Alan N
NO contest: nitrite versus S-nitroso-hemoglobin.
Circulation research 2004;94(7):851-5.
2004: Nath Karl A; Katusic Zvonimir S; Gladwin Mark T
The perfusion paradox and vascular instability in sickle cell disease.
Microcirculation (New York, N.Y. : 1994) 2004;11(2):179-93.
2004: Gladwin Mark T; Crawford Jack H; Patel Rakesh P
The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation.
Free radical biology & medicine 2004;36(6):707-17.
2004: Gladwin Mark T; Sachdev Vandana; Jison Maria L; Shizukuda Yukitaka; Plehn Jonathan F; Minter Karin; Brown Bernice; Coles Wynona A; Nichols James S; Ernst Inez; Hunter Lori A; Blackwelder William C; Schechter Alan N; Rodgers Griffin P; Castro Oswaldo; Ognibene Frederick P
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
The New England journal of medicine 2004;350(9):886-95.
2004: Patel Rakesh P; Gladwin Mark T
Physiologic, pathologic and therapeutic implications for hemoglobin interactions with nitric oxide.
Free radical biology & medicine 2004;36(4):399-401.
2004: Gladwin Mark T
Haldane, hot dogs, halitosis, and hypoxic vasodilation: the emerging biology of the nitrite anion.
The Journal of clinical investigation 2004;113(1):19-21.
2003: Cosby Kenyatta; Partovi Kristine S; Crawford Jack H; Patel Rakesh P; Reiter Christopher D; Martyr Sabrina; Yang Benjamin K; Waclawiw Myron A; Zalos Gloria; Xu Xiuli; Huang Kris T; Shields Howard; Kim-Shapiro Daniel B; Schechter Alan N; Cannon Richard O; Gladwin Mark T
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation.
Nature medicine 2003;9(12):1498-505.
2003: Xu Xiuli; Cho Man; Spencer Netanya Y; Patel Neil; Huang Zhi; Shields Howard; King S Bruce; Gladwin Mark T; Hogg Neil; Kim-Shapiro Daniel B
Measurements of nitric oxide on the heme iron and beta-93 thiol of human hemoglobin during cycles of oxygenation and deoxygenation.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11303-8.
2003: Zuzak Karel J; Gladwin Mark T; Cannon Richard O; Levin Ira W
Imaging hemoglobin oxygen saturation in sickle cell disease patients using noninvasive visible reflectance hyperspectral techniques: effects of nitric oxide.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H1183-9.
2003: Jison Maria L; Gladwin Mark T
Hemolytic anemia-associated pulmonary hypertension of sickle cell disease and the nitric oxide/arginine pathway.
American journal of respiratory and critical care medicine 2003;168(1):3-4.
2003: Gladwin Mark T; Lancaster Jack R; Freeman Bruce A; Schechter Alan N
Nitric oxide's reactions with hemoglobin: a view through the SNO-storm.
Nature medicine 2003;9(5):496-500.
2003: Schechter Alan N; Gladwin Mark T
Hemoglobin and the paracrine and endocrine functions of nitric oxide.
The New England journal of medicine 2003;348(15):1483-5.
2003: Huang Xiu-li; Pawliczak Rafal; Yao Xiang-lan; Cowan Mark J; Gladwin Mark T; Walter M J; Holtzman M J; Madara Patricia; Logun Carolea; Shelhamer James H
Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter.
The Journal of biological chemistry 2003;278(11):9298-308.
2003: Reiter Christopher D; Gladwin Mark T
An emerging role for nitric oxide in sickle cell disease vascular homeostasis and therapy.
Current opinion in hematology 2003;10(2):99-107.
2003: Yang Benjamin K; Vivas Esther X; Reiter Christopher D; Gladwin Mark T
Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples.
Free radical research 2003;37(1):1-10.
2003: Gladwin Mark T; Schechter Alan N; Ognibene Frederick P; Coles Wynona A; Reiter Christopher D; Schenke William H; Csako Gyorgy; Waclawiw Myron A; Panza Julio A; Cannon Richard O
Divergent nitric oxide bioavailability in men and women with sickle cell disease.
Circulation 2003;107(2):271-8.
2003: Cokic Vladan P; Smith Reginald D; Beleslin-Cokic Bojana B; Njoroge Joyce M; Miller Jeffery L; Gladwin Mark T; Schechter Alan N
Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase.
The Journal of clinical investigation 2003;111(2):231-9.
2002: Nanavaty Uday B; Pawliczak Rafal; Doniger Jeremy; Gladwin Mark T; Cowan Mark J; Logun Carolea; Shelhamer James H
Oxidant-induced cell death in respiratory epithelial cells is due to DNA damage and loss of ATP.
Experimental lung research 2002;28(8):591-607.
2002: Reiter Christopher D; Wang Xunde; Tanus-Santos Jose E; Hogg Neil; Cannon Richard O; Schechter Alan N; Gladwin Mark T
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease.
Nature medicine 2002;8(12):1383-9.
2002: Deem Steven; Kim Joung-Uk; Manjula Belur N; Acharya A Seetharama; Kerr Mark E; Patel Rakesh P; Gladwin Mark T; Swenson Erik R
Effects of S-nitrosation and cross-linking of hemoglobin on hypoxic pulmonary vasoconstriction in isolated rat lungs.
Circulation research 2002;91(7):626-32.
2002: Huang Xiu-Li; Pawliczak Rafal; Cowan Mark J; Gladwin Mark T; Madara Patricia; Logun Carolea; Shelhamer James H
Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells.
The Journal of biological chemistry 2002;277(41):38431-40.
2002: Hobbs Adrian J; Gladwin Mark T; Patel Rakesh P; Williams D Lyn H; Butler Anthony R
Haemoglobin: NO transporter, NO inactivator or NOne of the above?
Trends in pharmacological sciences 2002;23(9):406-11.
2002: Xu Xiuli; Lockamy Virginia L; Chen Kejing; Huang Zhi; Shields Howard; King S Bruce; Ballas Samir K; Nichols James S; Gladwin Mark T; Noguchi Constance T; Schechter Alan N; Kim-Shapiro Daniel B
Effects of iron nitrosylation on sickle cell hemoglobin solubility.
The Journal of biological chemistry 2002;277(39):36787-92.
2002: Gladwin Mark T; Wang Xunde; Reiter Christopher D; Yang Benjamin K; Vivas Esther X; Bonaventura Celia; Schechter Alan N
S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function.
The Journal of biological chemistry 2002;277(31):27818-28.
2002: Schechter Alan N; Gladwin Mark T; Cannon Richard O
NO solutions?
The Journal of clinical investigation 2002;109(9):1149-51.
2002: Gladwin Mark T; Shelhamer James H; Ognibene Frederick P; Pease-Fye Margaret E; Nichols James S; Link Beth; Patel Daksesh B; Jankowski Marcin A; Pannell Lewis K; Schechter Alan N; Rodgers Griffin P
Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease.
British journal of haematology 2002;116(2):436-44.
2001: Zuzak K J; Schaeberle M D; Gladwin M T; Cannon R O; Levin I W
Noninvasive determination of spatially resolved and time-resolved tissue perfusion in humans during nitric oxide inhibition and inhalation by use of a visible-reflectance hyperspectral imaging technique.
Circulation 2001;104(24):2905-10.
2001: Minter K R; Gladwin M T
Pulmonary complications of sickle cell anemia. A need for increased recognition, treatment, and research.
American journal of respiratory and critical care medicine 2001;164(11):2016-9.
2001: Noguchi C T; Gladwin M; Diwan B; Merciris P; Smith R; Yu X; Buzard G; Fitzhugh A; Keefer L K; Schechter A N; Mohandas N
Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele.
Blood cells, molecules & diseases 2001;27(6):971-7.
2001: Gladwin M T; Ognibene F P; Shelhamer J H; Pease-Fye M E; Noguchi C T; Rodgers G P; Schechter A N
Nitric oxide transport on sickle cell hemoglobin: where does it bind?
Free radical research 2001;35(2):175-80.
2001: Cannon R O; Schechter A N; Panza J A; Ognibene F P; Pease-Fye M E; Waclawiw M A; Shelhamer J H; Gladwin M T
Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery.
The Journal of clinical investigation 2001;108(2):279-87.
2001: Deem S; Gladwin M T; Berg J T; Kerr M E; Swenson E R
Effects of S-nitrosation of hemoglobin on hypoxic pulmonary vasoconstriction and nitric oxide flux.
American journal of respiratory and critical care medicine 2001;163(5):1164-70.
2001: Cowan M J; Gladwin M T; Shelhamer J H
Disorders of ciliary motility.
The American journal of the medical sciences 2001;321(1):3-10.
2000: Gladwin M T; Yao X L; Cowan M; Huang X L; Schneider R; Grant L R; Logun C; Shelhamer J H
Retinoic acid reduces p11 protein levels in bronchial epithelial cells by a posttranslational mechanism.
American journal of physiology. Lung cellular and molecular physiology 2000;279(6):L1103-9.
2000: Gladwin M T; Shelhamer J H; Schechter A N; Pease-Fye M E; Waclawiw M A; Panza J A; Ognibene F P; Cannon R O
Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11482-7.
2000: Hrinczenko B W; Alayash A I; Wink D A; Gladwin M T; Rodgers G P; Schechter A N
Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport.
British journal of haematology 2000;110(2):412-9.
2000: Gladwin M T; Ognibene F P; Pannell L K; Nichols J S; Pease-Fye M E; Shelhamer J H; Schechter A N
Relative role of heme nitrosylation and beta-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(18):9943-8.
1999: Gladwin M T; Schechter A N; Shelhamer J H; Pannell L K; Conway D A; Hrinczenko B W; Nichols J S; Pease-Fye M E; Noguchi C T; Rodgers G P; Ognibene F P
Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity.
The Journal of clinical investigation 1999;104(7):937-45.
1999: Gladwin M T; Slonim A; Landucci D L; Gutierrez D C; Cunnion R E
Cannulation of the internal jugular vein: is postprocedural chest radiography always necessary?
Critical care medicine 1999;27(9):1819-23.
1999: Yao X L; Cowan M J; Gladwin M T; Lawrence M M; Angus C W; Shelhamer J H
Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity.
The Journal of biological chemistry 1999;274(24):17202-8.
1999: Gladwin M T; Schechter A N; Shelhamer J H; Ognibene F P
The acute chest syndrome in sickle cell disease. Possible role of nitric oxide in its pathophysiology and treatment.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1368-76.

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