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Tibor Glant

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Rachel Rodeghero; Yanxia Cao; Tibor T Glant; Yoichiro Iwakua; Susan A Olalekan; Alison Finnegan
Location of CD4+ T Cell Priming Regulates the Differentiation of Th1 and Th17 Cells and Their Contribution to Arthritis.
Mark E Lauer; Katalin Mikecz; Paul L DeAngelis; Tibor T Glant; F Michael Haller; Vincent C Hascall; M Elaine Husni; Anthony Calabro
Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor necrosis factor-stimulated gene-6.
Colt Egelston; Tibor T Glant; Júlia Kurkó; Tibor A Rauch; Beata Tryniszewska; Timea Besenyei; Katalin Mikecz
Suppression of dendritic cell maturation and T cell proliferation by synovial fluid myeloid cells from mice with autoimmune arthritis.

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2013: Rachel Rodeghero; Yanxia Cao; Tibor T Glant; Yoichiro Iwakua; Susan A Olalekan; Alison Finnegan
Location of CD4+ T Cell Priming Regulates the Differentiation of Th1 and Th17 Cells and Their Contribution to Arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(11):5423-35.
2013: Mark E Lauer; Katalin Mikecz; Paul L DeAngelis; Tibor T Glant; F Michael Haller; Vincent C Hascall; M Elaine Husni; Anthony Calabro
Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor necrosis factor-stimulated gene-6.
The Journal of biological chemistry 2013;288(1):205-14.
2012: Colt Egelston; Tibor T Glant; Júlia Kurkó; Tibor A Rauch; Beata Tryniszewska; Timea Besenyei; Katalin Mikecz
Suppression of dendritic cell maturation and T cell proliferation by synovial fluid myeloid cells from mice with autoimmune arthritis.
Arthritis and rheumatism 2012;64(10):3179-88.
2012: Katalin Kis-Toth; Katalin Mikecz; Katalin Olasz; Marianna Radacs; Willem van Eden; Tibor T Glant
Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice.
International immunology 2012;24(8):507-17.
2012: Tamás Kobezda; Sheida Ghassemi-Nejad; Tibor T Glant; Katalin Mikecz
In vivo two-photon imaging of T cell motility in joint-draining lymph nodes in a mouse model of rheumatoid arthritis.
Cellular immunology 2012;278(1-2):158-65.
2012: Anjali Nair; Greg T Spear; Nikhil Verma; Charles Bush-Joseph; Susan Chubinskaya; Mary K Crow; Alison Finnegan; Tibor T Glant; Veero Kanda; Anne-Marie Malfait; Katalin Mikecz; Carla R Scanzello
Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14.
Arthritis and rheumatism 2012;64(7):2268-77.
2012: Jelena M Kezic; James T Rosenbaum; Michael P Davey; Tibor T Glant; Holly L Rosenzweig
Interferon-γ regulates discordant mechanisms of uveitis versus joint and axial disease in a murine model resembling spondylarthritis.
Arthritis and rheumatism 2012;64(3):762-71.
2012: Timea Besenyei; Tibor T Glant; Andras Kadar; Julia Kurko; Katalin Mikecz; Tibor A Rauch; Beata Tryniszewska; Zoltán Szekanecz
Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models.
Clinical & developmental immunology 2012;2012():284751.
2012: Jelena M Kezic; James T Rosenbaum; Tibor T Glant; Holly L Rosenzweig
Neutralization of IL-17 ameliorates uveitis but damages photoreceptors in a murine model of spondyloarthritis.
Arthritis research & therapy 2012;14(1):R18.
2011: Keith M Hamel; Marilyn R Kehry; Yumei Wang; Tibor T Glant; Susan Ashaye; Yanxia Cao; Robert Dunn; Alison Finnegan
B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(9):4900-6.
2011: Gyorgy Nagyeri; Katalin Olasz; Marianna Radacs; Beata Tryniszewska; Sheida Ghassemi-Nejad; Tibor T Glant; Zsuzsa Gyorfy; Vincent C Hascall; Gabor Hutas; Katalin Mikecz
TSG-6 protein, a negative regulator of inflammatory arthritis, forms a ternary complex with murine mast cell tryptases and heparin.
The Journal of biological chemistry 2011;286(26):23559-69.
2011: Tibor T Glant; Marianna Radacs; Gyorgy Nagyeri; Katalin Olasz; Anna Laszlo; Ferenc Boldizsar; Akos Hegyi; Alison Finnegan; Katalin Mikecz
Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.
Arthritis and rheumatism 2011;63(5):1312-21.
2011: Andrew B Nesterovitch; Sandor Szanto; Andrea Gonda; Tamas Bardos; Katalin Kis-Toth; Vyacheslav Adarichev; Katalin Olasz; Sheida Ghassemi-Najad; Mark D Hoffman; Michael D Tharp; Katalin Mikecz; Tibor T Glant
Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans.
The American journal of pathology 2011;178(4):1701-14.
2011: Andrew B Nesterovitch; Zsuzsa Gyorfy; Mark D Hoffman; Ellen C Moore; Nada Elbuluk; Beata Tryniszewska; Tibor A Rauch; Melinda Simon; Sewon Kang; Gary J Fisher; Katalin Mikecz; Michael D Tharp; Tibor T Glant
Alteration in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6/SHP1) may contribute to neutrophilic dermatoses.
The American journal of pathology 2011;178(4):1434-41.
2010: Ferenc Boldizsar; Katalin Kis-Toth; Oktavia Tarjanyi; Katalin Olasz; Akos Hegyi; Katalin Mikecz; Tibor T Glant
Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice.
Arthritis and rheumatism 2010;62(10):2984-94.
2010: Daniela Carulli; Tommaso Pizzorusso; Jessica C F Kwok; Elena Putignano; Andrea Poli; Serhiy Forostyak; Melissa R Andrews; Sarama Sathyaseelan Deepa; Tibor T Glant; James W Fawcett
Animals lacking link protein have attenuated perineuronal nets and persistent plasticity.
Brain : a journal of neurology 2010;133(Pt 8):2331-47.
2010: Ferenc Boldizsar; Katalin Mikecz; Tibor T Glant
Immunosenescence and its potential modulation: lessons from mouse models.
Expert review of clinical immunology 2010;6(3):353-7.
2010: Paul D Doodes; Yanxia Cao; Keith M Hamel; Yumei Wang; Rachel L Rodeghero; Katalin Mikecz; Tibor T Glant; Yoichiro Iwakura; Alison Finnegan
IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1552-9.
2010: Adrienn Angyal; Colt Egelston; Tamás Kobezda; Katalin Olasz; Anna László; Tibor T Glant; Katalin Mikecz
Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.
Arthritis research & therapy 2010;12(2):R44.
2009: Anikó Végvári; Zoltán Szabó; Sándor Szántó; Tibor T Glant; Katalin Mikecz; Zoltán Szekanecz
The genetic background of ankylosing spondylitis.
Joint, bone, spine : revue du rhumatisme 2009;76(6):623-8.
2009: Ferenc Boldizsar; Oktavia Tarjanyi; Peter Nemeth; Katalin Mikecz; Tibor T Glant
Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice.
International immunology 2009;21(5):511-22.
2009: Oktavia Tarjanyi; Ferenc Boldizsar; Peter Nemeth; Katalin Mikecz; Tibor T Glant
Age-related changes in arthritis susceptibility and severity in a murine model of rheumatoid arthritis.
Immunity & ageing : I & A 2009;6():8.
2009: Balint Farkas; Ferenc Boldizsar; Oktavia Tarjanyi; Anna Laszlo; Simon M Lin; Gabor Hutas; Beata Tryniszewska; Aaron Mangold; Gyorgy Nagyeri; Holly L Rosenzweig; Alison Finnegan; Katalin Mikecz; Tibor T Glant
BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.
Arthritis research & therapy 2009;11(1):R21.
2009: Lotte Wieten; Suzanne E Berlo; Corlinda B Ten Brink; Peter van Kooten; Mahavir Singh; Ruurd van der Zee; Tibor T Glant; Femke Broere; Willem van Eden
IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis.
PloS one 2009;4(1):e4186.
2008: Gábor Hutás; Eva Bajnok; István Gál; Alison Finnegan; Tibor T Glant; Katalin Mikecz
CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis.
Blood 2008;112(13):4999-5006.
2008: Vyacheslav Adarichev; A Vegvari; Z Szabo; Katalin Kis-Toth; Katalin Mikecz; Tibor T Glant
Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation.
Genes and immunity 2008;9(7):591-601.
2008: Miklos Tunyogi-Csapo; Katalin Kis-Toth; Marianna Radacs; Balint Farkas; Joshua J Jacobs; Alison Finnegan; Katalin Mikecz; Tibor T Glant
Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption.
Arthritis and rheumatism 2008;58(8):2397-408.
2008: Tibor T Glant; Sándor Szántó; Aniko Vegvari; Zoltan Szabo; Katalin Kis-Toth; Katalin Mikecz; Vyacheslav Adarichev
Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1307-14.
2008: Yanxia Cao; Paul D Doodes; Tibor T Glant; Alison Finnegan
IL-27 induces a Th1 immune response and susceptibility to experimental arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):922-30.
2007: Miklos Tunyogi-Csapo; Tamas Koreny; Csaba Vermes; Jorge O Galante; Joshua J Jacobs; Tibor T Glant
Role of fibroblasts and fibroblast-derived growth factors in periprosthetic angiogenesis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2007;25(10):1378-88.
2007: Yanxia Cao; Frank Brombacher; Miklos Tunyogi-Csapo; Tibor T Glant; Alison Finnegan
Interleukin-4 regulates proteoglycan-induced arthritis by specifically suppressing the innate immune response.
Arthritis and rheumatism 2007;56(3):861-70.
2007: Sándor Szántó; Tamas Koreny; Katalin Mikecz; Tibor T Glant; Zoltán Szekanecz; John Varga
Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice.
Arthritis research & therapy 2007;9(3):R50.
2007: Shannon K O'Neill; Tibor T Glant; Alison Finnegan
The role of B cells in animal models of rheumatoid arthritis.
Frontiers in bioscience : a journal and virtual library 2007;12():1722-36.
2006: Vyacheslav Adarichev; Csaba Vermes; Anita Hanyecz; Katalin Kis-Toth; Miklos Tunyogi-Csapo; Alison Finnegan; Katalin Mikecz; Tibor T Glant
Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis.
Autoimmunity 2006;39(8):663-73.
2006: Tamas Koreny; Miklós Tunyogi-Csapó; István Gál; Csaba Vermes; Joshua J Jacobs; Tibor T Glant
The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis.
Arthritis and rheumatism 2006;54(10):3221-32.
2006: Suzanne E Berlo; Teun Guichelaar; Corlinda B Ten Brink; Peter van Kooten; Femke Broere; Katalin Kis-Toth; Willem van Eden; Chris P M Broeren; Tibor T Glant
Increased arthritis susceptibility in cartilage proteoglycan-specific T cell receptor-transgenic mice.
Arthritis and rheumatism 2006;54(8):2423-33.
2006: Bara Sarraj; Katalin Kis-Toth; Tibor T Glant; Alison Finnegan; Katalin Mikecz
Expression of CD44 and L-selectin in the innate immune system is required for severe joint inflammation in the proteoglycan-induced murine model of rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1932-40.
2006: Vyacheslav Adarichev; Tibor T Glant
Experimental spondyloarthropathies: animal models of ankylosing spondylitis.
Current rheumatology reports 2006;8(4):267-74.
2006: Elizabeth A Fritz; Tibor T Glant; Csaba Vermes; Joshua J Jacobs; Kenneth A Roebuck
Chemokine gene activation in human bone marrow-derived osteoblasts following exposure to particulate wear debris.
Journal of biomedical materials research. Part A 2006;77(1):192-201.
2005: Suzanne E Berlo; Peter van Kooten; Corlinda B Ten Brink; Femke Broere; Mariëtte A Oosterwegel; Tibor T Glant; Willem van Eden; Chris P M Broeren
Naive transgenic T cells expressing cartilage proteoglycan-specific TCR induce arthritis upon in vivo activation.
Journal of autoimmunity 2005;25(3):172-80.
2005: Yanal Murad; Zoltán Szabó; Katalin Kis-Toth; Tibor T Glant
Molecular manipulation with the arthritogenic epitopes of the G1 domain of human cartilage proteoglycan aggrecan.
Clinical and experimental immunology 2005;142(2):303-11.
2005: Elizabeth A Fritz; Joshua J Jacobs; Tibor T Glant; Kenneth A Roebuck
Chemokine IL-8 induction by particulate wear debris in osteoblasts is mediated by NF-kappaB.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2005;23(6):1249-57.
2005: István Gál; Eva Bajnok; Sándor Szántó; Bara Sarraj; Tibor T Glant; Katalin Mikecz
Visualization and in situ analysis of leukocyte trafficking into the ankle joint in a systemic murine model of rheumatoid arthritis.
Arthritis and rheumatism 2005;52(10):3269-78.
2005: Andrea Gonda; István Gál; Sándor Szántó; Bara Sarraj; Tibor T Glant; János Hunyadi; Katalin Mikecz
CD44, but not l-selectin, is critically involved in leucocyte migration into the skin in a murine model of allergic dermatitis.
Experimental dermatology 2005;14(9):700-8.
2005: Anikó Végvári; Zoltán Szabó; Sándor Szántó; Andrew B Nesterovitch; Katalin Mikecz; Tibor T Glant; Vyacheslav Adarichev
Two major interacting chromosome loci control disease susceptibility in murine model of spondyloarthropathy.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2475-83.
2005: Zoltán Szabó; Sándor Szántó; Anikó Végvári; Zoltán Szekanecz; Katalin Mikecz; Tibor T Glant
Genetic control of experimental spondylarthropathy.
Arthritis and rheumatism 2005;52(8):2452-60.
2005: Tamás Bárdos; Zoltán Szabó; Matyas Czipri; Csaba Vermes; M Tunyogi-Csapó; Robert M Urban; Katalin Mikecz; Tibor T Glant
A longitudinal study on an autoimmune murine model of ankylosing spondylitis.
Annals of the rheumatic diseases 2005;64(7):981-7.
2005: Edit Buzás; Anikó Végvári; Yanal Murad; Alison Finnegan; Katalin Mikecz; Tibor T Glant
T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis.
Cellular immunology 2005;235(2):98-108.
2005: Shannon K O'Neill; Mark J Shlomchik; Tibor T Glant; Yanxia Cao; Paul D Doodes; Alison Finnegan
Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3781-8.
2005: Nadim J Hallab; Shelley Anderson; Tiffany Stafford; Tibor T Glant; Joshua J Jacobs
Lymphocyte responses in patients with total hip arthroplasty.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2005;23(2):384-91.
2005: Vyacheslav Adarichev; Csaba Vermes; Anita Hanyecz; Katalin Mikecz; Eric G Bremer; Tibor T Glant
Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation.
Arthritis research & therapy 2005;7(2):R196-207.
2004: Dongdong Li; István Gál; Csaba Vermes; Maria-Luisa Alegre; Anita S Chong; Lieping Chen; Qing Shao; Vyacheslav Adarichev; Xuemei Xu; Tamas Koreny; Katalin Mikecz; Alison Finnegan; Tibor T Glant; Jian Zhang
Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7135-9.
2004: Sándor Szántó; Tamás Bárdos; István Gál; Tibor T Glant; Katalin Mikecz
Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice.
Arthritis and rheumatism 2004;50(9):3012-22.
2004: Csaba Vermes; Raman Chandrasekaran; J G Dobai; Joshua J Jacobs; Gunnar B J Andersson; H An; Nadim J Hallab; Jorge O Galante; Tibor T Glant
The combination of pamidronate and calcitriol reverses particle- and TNF-alpha-induced altered functions of bone-marrow-derived stromal cells with osteoblastic phenotype.
The Journal of bone and joint surgery. British volume 2004;86(5):759-70.
2004: Sándor Szántó; Tamás Bárdos; Zoltán Szabó; Chella S David; Edit Buzás; Katalin Mikecz; Tibor T Glant
Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.
Arthritis and rheumatism 2004;50(6):1984-95.
2004: Sándor Szántó; István Gál; Andrea Gonda; Tibor T Glant; Katalin Mikecz
Expression of L-selectin, but not CD44, is required for early neutrophil extravasation in antigen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6723-34.
2004: Anita Hanyecz; Suzanne E Berlo; Sándor Szántó; Chris P M Broeren; Katalin Mikecz; Tibor T Glant
Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype.
Arthritis and rheumatism 2004;50(5):1665-76.
2004: Tibor T Glant; Vyacheslav Adarichev; Andrew B Nesterovitch; S Szanto; J P Oswald; Joshua J Jacobs; Gábor Firneisz; Jian Zhang; Alison Finnegan; Katalin Mikecz
Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis.
The American journal of the medical sciences 2004;327(4):188-95.
2004: Tibor T Glant; Katalin Mikecz
Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis.
Methods in molecular medicine 2004;102():313-38.
2003: Matyas Czipri; Jeffrey M Otto; Gabriella Cs-Szabó; Rajesh V Kamath; Csaba Vermes; Gábor Firneisz; Kevin J Kolman; Hideto Watanabe; Yefu Li; Peter J Roughley; Yoshihiko Yamada; Björn R Olsen; Tibor T Glant
Genetic rescue of chondrodysplasia and the perinatal lethal effect of cartilage link protein deficiency.
The Journal of biological chemistry 2003;278(40):39214-23.
2003: Anita Hanyecz; Tamás Bárdos; Suzanne E Berlo; Edit Buzás; Andrew B Nesterovitch; Katalin Mikecz; Tibor T Glant
Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan.
Arthritis and rheumatism 2003;48(10):2959-73.
2003: Gábor Firneisz; Idit Zehavi; Csaba Vermes; Anita Hanyecz; Joshua A Frieman; Tibor T Glant
Identification and quantification of disease-related gene clusters.
Bioinformatics (Oxford, England) 2003;19(14):1781-6.
2003: Edit Buzás; Anita Hanyecz; Yanal Murad; Ferenc Hudecz; Eva Rajnavölgyi; Katalin Mikecz; Tibor T Glant
Differential recognition of altered peptide ligands distinguishes two functionally discordant (arthritogenic and nonarthritogenic) autoreactive T cell hybridoma clones.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3025-33.
2003: Zsuzsanna Ortutay; Anna Polgár; Béla Gömör; Pál Géher; Tamás Lakatos; Tibor T Glant; Renate E Gay; Steffen GAY; Eva Pállinger; Csaba Farkas; Eva Farkas; László Tóthfalusi; Katalin Kocsis; András Falus; Edit Buzás
Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion.
Arthritis and rheumatism 2003;48(8):2163-72.
2003: Wenhua Liu; Nancy I Burton-Wurster; Tibor T Glant; Scott Tashman; Dale R Sumner; Rajesh V Kamath; George Lust; James H Kimura; Gabriella Cs-Szabo
Spontaneous and experimental osteoarthritis in dog: similarities and differences in proteoglycan levels.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2003;21(4):730-7.
2003: Vyacheslav Adarichev; Andrew B Nesterovitch; Tamás Bárdos; Darci Biesczat; Raman Chandrasekaran; Csaba Vermes; Katalin Mikecz; Alison Finnegan; Tibor T Glant
Sex effect on clinical and immunologic quantitative trait loci in a murine model of rheumatoid arthritis.
Arthritis and rheumatism 2003;48(6):1708-20.
2003: Csaba Fülöp; Sándor Szántó; Durba Mukhopadhyay; Tamás Bárdos; Rajesh V Kamath; Marylin S Rugg; Anthony J Day; Antonietta Salustri; Vincent C Hascall; Tibor T Glant; Katalin Mikecz
Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice.
Development (Cambridge, England) 2003;130(10):2253-61.
2003: Jian Zhang; Tamás Bárdos; Qing Shao; Jurg Tschopp; Katalin Mikecz; Tibor T Glant; Alison Finnegan
IL-4 potentiates activated T cell apoptosis via an IL-2-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3495-503.
2003: Vyacheslav Adarichev; Juan C Valdez; Tamás Bárdos; Alison Finnegan; Katalin Mikecz; Tibor T Glant
Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2283-92.
2003: Tibor T Glant
Short overview of potential gene therapy approaches in orthopedic spine surgery.
Spine 2003;28(3):207-8.
2003: Tibor T Glant; Alison Finnegan; Katalin Mikecz
Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics.
Critical reviews in immunology 2003;23(3):199-250.
2003: Alison Finnegan; Charles D Kaplan; Yanxia Cao; Hermann Eibel; Tibor T Glant; Jian Zhang
Collagen-induced arthritis is exacerbated in IL-10-deficient mice.
Arthritis research & therapy 2003;5(1):R18-24.
2002: Tamás Bárdos; Jian Zhang; Katalin Mikecz; Chella S David; Tibor T Glant
Mice lacking endogenous major histocompatibility complex class II develop arthritis resembling psoriatic arthritis at an advanced age.
Arthritis and rheumatism 2002;46(9):2465-75.
2002: reinout stoop; István Gál; Tibor T Glant; John McNeish; Katalin Mikecz
Trafficking of CD44-deficient murine lymphocytes under normal and inflammatory conditions.
European journal of immunology 2002;32(9):2532-42.
2002: Jian Zhang; Tamás Bárdos; Dongdong Li; István Gál; Csaba Vermes; Jianye Xu; Katalin Mikecz; Alison Finnegan; Stan Lipkowitz; Tibor T Glant
Cutting edge: regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquitination.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2236-40.
2002: Tibor T Glant; Rajesh V Kamath; Tamás Bárdos; István Gál; Sándor Szántó; Yanal Murad; John D Sandy; John S Mort; Peter J Roughley; Katalin Mikecz
Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis.
Arthritis and rheumatism 2002;46(8):2207-18.
2002: Tamás Bárdos; Matyas Czipri; Csaba Vermes; Jian Zhang; Katalin Mikecz; Tibor T Glant
Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice.
Clinical and experimental immunology 2002;129(2):224-31.
2002: Tamás Bárdos; Katalin Mikecz; Alison Finnegan; Jian Zhang; Tibor T Glant
T and B cell recovery in arthritis adoptively transferred to SCID mice: antigen-specific activation is required for restoration of autopathogenic CD4+ Th1 cells in a syngeneic system.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6013-21.
2002: Nadim J Hallab; Csaba Vermes; Carlo Messina; Kenneth A Roebuck; Tibor T Glant; Joshua J Jacobs
Concentration- and composition-dependent effects of metal ions on human MG-63 osteoblasts.
Journal of biomedical materials research 2002;60(3):420-33.
2002: Vyacheslav Adarichev; Tamás Bárdos; Stilliani Christodoulou; Mathew T Phillips; Katalin Mikecz; Tibor T Glant
Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis.
Immunogenetics 2002;54(3):184-92.
2002: Csaba Vermes; Joshua J Jacobs; Jian Zhang; Gábor Firneisz; Kenneth A Roebuck; Tibor T Glant
Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts.
The Journal of biological chemistry 2002;277(19):16879-87.
2002: Elizabeth A Fritz; Tibor T Glant; Csaba Vermes; Joshua J Jacobs; Kenneth A Roebuck
Titanium particles induce the immediate early stress responsive chemokines IL-8 and MCP-1 in osteoblasts.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2002;20(3):490-8.
2002: Gábor Firneisz; Péter Lakatos; Ferenc Szalay; Claudia Polli; Tibor T Glant; Peter Ferenci
Common mutations of ATP7B in Wilson disease patients from Hungary.
American journal of medical genetics 2002;108(1):23-8.
2002: Tibor T Glant
Point of view.
Spine 2002;27(4):368.
2002: Charles Kaplan; Juan C Valdez; Raman Chandrasekaran; Hermann Eibel; Katalin Mikecz; Tibor T Glant; Alison Finnegan
Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis.
Arthritis research 2002;4(1):54-8.
2001: Joshua J Jacobs; Kenneth A Roebuck; Michael J Archibeck; Nadim J Hallab; Tibor T Glant
Osteolysis: basic science.
Clinical orthopaedics and related research 2001;(393):71-7.
2001: Csaba Vermes; Tibor T Glant; Nadim J Hallab; Elizabeth A Fritz; Kenneth A Roebuck; Joshua J Jacobs
The potential role of the osteoblast in the development of periprosthetic osteolysis: review of in vitro osteoblast responses to wear debris, corrosion products, and cytokines and growth factors.
The Journal of arthroplasty 2001;16(8 Suppl 1):95-100.
2001: Tamás Bárdos; Rajesh V Kamath; Katalin Mikecz; Tibor T Glant
Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis.
The American journal of pathology 2001;159(5):1711-21.
2001: Jian Zhang; Tamás Bárdos; Katalin Mikecz; Alison Finnegan; Tibor T Glant
Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(8):4981-6.
2001: Kenneth A Roebuck; Csaba Vermes; Laura R Carpenter; Elizabeth A Fritz; R Narayanan; Tibor T Glant
Down-regulation of procollagen alpha1[I]] messenger RNA by titanium particles correlates with nuclear factor kappaB (NF-kappaB) activation and increased rel A and NF-kappaB1 binding to the collagen promoter.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(3):501-10.
2001: Tibor T Glant; Tamás Bárdos; Csaba Vermes; Raman Chandrasekaran; J C Valdéz; Jeffrey M Otto; D Gerard; S Velins; G Lovász; J Zhang; Katalin Mikecz; Alison Finnegan
Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease.
Arthritis and rheumatism 2001;44(3):682-92.
2001: Csaba Vermes; Raman Chandrasekaran; Joshua J Jacobs; Jorge O Galante; Kenneth A Roebuck; Tibor T Glant
The effects of particulate wear debris, cytokines, and growth factors on the functions of MG-63 osteoblasts.
The Journal of bone and joint surgery. American volume 2001;83-A(2):201-11.
2001: Michael J Archibeck; Joshua J Jacobs; Kenneth A Roebuck; Tibor T Glant
The basic science of periprosthetic osteolysis.
Instructional course lectures 2001;50():185-95.
2000: Jeffrey M Otto; R Chandrasekeran; Csaba Vermes; Katalin Mikecz; Alison Finnegan; S E Rickert; J T Enders; Tibor T Glant
A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5278-86.
2000: Jian Zhang; Katalin Mikecz; Alison Finnegan; Tibor T Glant
Spontaneous thymocyte apoptosis is regulated by a mitochondrion-mediated signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):2970-4.
2000: Csaba Vermes; Kenneth A Roebuck; Raman Chandrasekaran; J G Dobai; Joshua J Jacobs; Tibor T Glant
Particulate wear debris activates protein tyrosine kinases and nuclear factor kappaB, which down-regulates type I collagen synthesis in human osteoblasts.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(9):1756-65.
2000: J H Kim; Tibor T Glant; Jayne Lesley; Robert Hyman; Katalin Mikecz
Adhesion of lymphoid cells to CD44-specific substrata: the consequences of attachment depend on the ligand.
Experimental cell research 2000;256(2):445-53.
2000: Krisztina Holló; Tibor T Glant; M Garzó; Alison Finnegan; Katalin Mikecz; Edit Buzás
Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis.
Clinical and experimental immunology 2000;120(1):167-73.
1999: Jeffrey M Otto; Gabriella Cs-Szabó; J Gallagher; S Velins; Katalin Mikecz; Edit Buzás; J T Enders; Y Li; B R Olsen; Tibor T Glant
Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis.
Arthritis and rheumatism 1999;42(12):2524-31.
1999: Alison Finnegan; Katalin Mikecz; P Tao; Tibor T Glant
Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5383-90.
1998: Tibor T Glant; Gabriella Cs-Szabó; H Nagase; Joshua J Jacobs; Katalin Mikecz
Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.
Arthritis and rheumatism 1998;41(6):1007-18.
1998: Tibor T Glant; Edit Buzás; Alison Finnegan; G Negroiu; Gabriella Cs-Szabó; Katalin Mikecz
Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3812-9.
1997: Csaba Fülöp; Rajesh V Kamath; Y Li; J M Otto; Antonietta Salustri; B R Olsen; Tibor T Glant; Vincent C Hascall
Coding sequence, exon-intron structure and chromosomal localization of murine TNF-stimulated gene 6 that is specifically expressed by expanding cumulus cell-oocyte complexes.
Gene 1997;202(1-2):95-102.
1997: A S Shanbhag; Joshua J Jacobs; J Black; Jorge O Galante; Tibor T Glant
Effects of particles on fibroblast proliferation and bone resorption in vitro.
Clinical orthopaedics and related research 1997;(342):205-17.
1997: Gabriella Cs-Szabó; Lee I Melching; Peter J Roughley; Tibor T Glant
Changes in messenger RNA and protein levels of proteoglycans and link protein in human osteoarthritic cartilage samples.
Arthritis and rheumatism 1997;40(6):1037-45.
1997: FR Brennan; K Mikecz; Tibor T Glant; Paresh Jobanputra; S Pinder; C Bavington; P Morrison; George Nuki
CD44 expression by leucocytes in rheumatoid arthritis and modulation by specific antibody: implications for lymphocyte adhesion to endothelial cells and synoviocytes in vitro.
Scandinavian journal of immunology 1997;45(2):213-20.
1997: S H Lee; FR Brennan; Joshua J Jacobs; Robert M Urban; D R Ragasa; Tibor T Glant
Human monocyte/macrophage response to cobalt-chromium corrosion products and titanium particles in patients with total joint replacements.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1997;15(1):40-9.
1997: J Yao; Gabriella Cs-Szabó; Joshua J Jacobs; K E Kuettner; Tibor T Glant
Suppression of osteoblast function by titanium particles.
The Journal of bone and joint surgery. American volume 1997;79(1):107-12.
1996: Csaba Fülöp; Gabriella Cs-Szabó; Tibor T Glant
Species-specific alternative splicing of the epidermal growth factor-like domain 1 of cartilage aggrecan.
The Biochemical journal 1996;319 ( Pt 3)():935-40.
1995: F R Brennan; Katalin Mikecz; Edit Buzás; D Ragasa; Gabriella Cs-Szabó; G Negroiu; Tibor T Glant
Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.
Clinical and experimental immunology 1995;101(3):414-21.
1995: Edit Buzás; F R Brennan; Katalin Mikecz; M Garzó; G Negroiu; K Holló; Gabriella Cs-Szabó; E Pintye; Tibor T Glant
A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(5):2679-87.
1995: J Yao; Tibor T Glant; M W Lark; Katalin Mikecz; Joshua J Jacobs; N I Hutchinson; L A Hoerrner; Klaus E Kuettner; Jorge O Galante
The potential role of fibroblasts in periprosthetic osteolysis: fibroblast response to titanium particles.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(9):1417-27.
1995: A S Shanbhag; Joshua J Jacobs; J Black; Jorge O Galante; Tibor T Glant
Human monocyte response to particulate biomaterials generated in vivo and in vitro.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1995;13(5):792-801.
1995: A S Shanbhag; Joshua J Jacobs; J Black; Jorge O Galante; Tibor T Glant
Cellular mediators secreted by interfacial membranes obtained at revision total hip arthroplasty.
The Journal of arthroplasty 1995;10(4):498-506.
1995: Katalin Mikecz; F R Brennan; J H Kim; Tibor T Glant
Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis.
Nature medicine 1995;1(6):558-63.
1995: Gabriella Cs-Szabó; Peter J Roughley; A H Plaas; Tibor T Glant
Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage.
Arthritis and rheumatism 1995;38(5):660-8.
1995: F R Brennan; G Negroiu; Edit Buzás; Csaba Fülöp; K Holló; Katalin Mikecz; Tibor T Glant
Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.
Clinical and experimental immunology 1995;100(1):104-10.
1995: F R Brennan; Katalin Mikecz; Edit Buzás; Tibor T Glant
Interferon-gamma but not granulocyte/macrophage colony-stimulating factor augments proteoglycan presentation by synovial cells and chondrocytes to an autopathogenic T cell hybridoma.
Immunology letters 1995;45(1-2):87-91.
1995: Katalin Mikecz; F R Brennan; J H Kim; Tibor T Glant
The role of adhesion molecules in the development of autoimmune arthritis.
Scandinavian journal of rheumatology. Supplement 1995;101():99-106.
1995: Tibor T Glant; Csaba Fülöp; Gabriella Cs-Szabó; Edit Buzás; D Ragasa; Katalin Mikecz
Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis.
Scandinavian journal of rheumatology. Supplement 1995;101():43-9.
1994: Edit Buzás; Katalin Mikecz; F R Brennan; Tibor T Glant
Mediators and autopathogenic effector cells in proteoglycan-induced arthritic and clinically asymptomatic BALB/c mice.
Cellular immunology 1994;158(2):292-304.
1994: Katalin Mikecz; Tibor T Glant
Migration and homing of lymphocytes to lymphoid and synovial tissues in proteoglycan-induced murine arthritis.
Arthritis and rheumatism 1994;37(9):1395-403.
1994: Tibor T Glant; Joshua J Jacobs
Response of three murine macrophage populations to particulate debris: bone resorption in organ cultures.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1994;12(5):720-31.
1994: E Walcz; F Deák; P Erhardt; S N Coulter; Csaba Fülöp; P Horvath; K J Doege; Tibor T Glant
Complete coding sequence, deduced primary structure, chromosomal localization, and structural analysis of murine aggrecan.
Genomics 1994;22(2):364-71.
1994: A S Shanbhag; Joshua J Jacobs; Tibor T Glant; J L Gilbert; J Black; Jorge O Galante
Composition and morphology of wear debris in failed uncemented total hip replacement.
The Journal of bone and joint surgery. British volume 1994;76(1):60-7.
1994: A S Shanbhag; Joshua J Jacobs; J Black; Jorge O Galante; Tibor T Glant
Macrophage/particle interactions: effect of size, composition and surface area.
Journal of biomedical materials research 1994;28(1):81-90.
1993: Edit Buzás; K Holló; L Rubliczky; M Garzó; Peter Nyirkos; Tibor T Glant
Effect of pregnancy on proteoglycan-induced progressive polyarthritis in BALB/c mice: remission of disease activity.
Clinical and experimental immunology 1993;94(2):252-60.
1993: Tibor T Glant; Joshua J Jacobs; G Molnár; A S Shanbhag; M Valyon; Jorge O Galante
Bone resorption activity of particulate-stimulated macrophages.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(9):1071-9.
1993: Csaba Fülöp; E Walcz; M Valyon; Tibor T Glant
Expression of alternatively spliced epidermal growth factor-like domains in aggrecans of different species. Evidence for a novel module.
The Journal of biological chemistry 1993;268(23):17377-83.
1993: Gabriella Cs-Szabó; Csaba Fülöp; C Hadházy; P Elödi; Tibor T Glant
Substrate specificity of 'elastomucoproteinase': an enzyme which can degrade cartilage aggrecan.
Biochimica et biophysica acta 1993;1162(3):266-74.
1993: James M Williams; J Zurawski; Katalin Mikecz; Tibor T Glant
Functional assessment of joint use in experimental inflammatory murine arthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1993;11(2):172-80.
1993: A M Sárközi; G Hámori; Csaba Fülöp; E Búzás; M Brózik; K Merétey; Tibor T Glant
[Serum keratan sulfate studies and their significance in the evaluation of cartilage degradation in degenerative and inflammatory joint diseases].
Orvosi hetilap 1993;134(9):461-7.
1992: Eugene Thonar; Tibor T Glant
Serum keratan sulfate--a marker of predisposition to polyarticular osteoarthritis.
Clinical biochemistry 1992;25(3):175-80.
1992: Tibor T Glant; Katalin Mikecz; RR Bartlett; F Deák; Eugene Thonar; J M Williams; T Mattar; Klaus E Kuettner; R Schleyerbach
Immunomodulation of proteoglycan-induced progressive polyarthritis by leflunomide.
Immunopharmacology 1992;23(2):105-16.
1991: Eugene Thonar; D M Manicourt; J Williams; Mary Ellen Lenz; M B Sweet; Thomas J Schnitzer; L Otten; Tibor T Glant; Klaus E Kuettner
Circulating keratan sulfate: a marker of cartilage proteoglycan catabolism in osteoarthritis.
The Journal of rheumatology. Supplement 1991;27():24-6.
1990: Tibor T Glant; Csaba Fülöp; Katalin Mikecz; Edit Buzás; G Molnár; P Erhardt
Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases.
Biochemical Society transactions 1990;18(5):796-9.
1990: E Dayer; L Mathai; Tibor T Glant; Katalin Mikecz; A Robin Poole
Cartilage proteoglycan-induced arthritis in BALB/c mice. Antibodies that recognize human and mouse cartilage proteoglycan and can cause depletion of cartilage proteoglycan with little or no synovitis.
Arthritis and rheumatism 1990;33(9):1394-405.
1990: Katalin Mikecz; Tibor T Glant; Edit Buzás; A Robin Poole
Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice.
Arthritis and rheumatism 1990;33(6):866-76.
1988: Katalin Mikecz; Tibor T Glant; M Baron; A Robin Poole
Isolation of proteoglycan-specific T lymphocytes from patients with ankylosing spondylitis.
Cellular immunology 1988;112(1):55-63.
1988: Katalin Mikecz; Tibor T Glant; Edit Buzás; A R Poole
Cartilage proteoglycans as potential autoantigens in humans and in experimental animals.
Agents and actions 1988;23(1-2):63-6.
1987: C Webber; Tibor T Glant; Peter J Roughley; A Robin Poole
The identification and characterization of two populations of aggregating proteoglycans of high buoyant density isolated from post-natal human articular cartilages of different ages.
The Biochemical journal 1987;248(3):735-40.
1987: Katalin Mikecz; Tibor T Glant; A R Poole
Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan.
Arthritis and rheumatism 1987;30(3):306-18.
1987: Tibor T Glant; Katalin Mikecz; A Arzoumanian; A R Poole
Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology.
Arthritis and rheumatism 1987;30(2):201-12.
1986: Tibor T Glant; Katalin Mikecz; P J Roughley; Edit Buzás; A Robin Poole
Age-related changes in protein-related epitopes of human articular-cartilage proteoglycans.
The Biochemical journal 1986;236(1):71-5.
1986: Tibor T Glant; Katalin Mikecz; A R Poole
Monoclonal antibodies to different protein-related epitopes of human articular cartilage proteoglycans.
The Biochemical journal 1986;234(1):31-41.
1980: Tibor T Glant; J Csongor; T Szücs
Immunopathologic role of proteoglycan antigens in rheumatoid joint disease.
Scandinavian journal of immunology 1980;11(3):247-52.