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Hansruedi Glatt
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33
Meinl, Walter
24
Oesch, Franz
12
Pabel, Ulrike
12
Seidel, Albrecht
10
Coughtrie, Michael
8
Falany, Charles
8
Phillips, David
8
Platt, Karl
7
Seidel, Albrecht
7
Friedberg, Thomas
6
Doehmer, Johannes
6
Bakhiya, Nadiya
6
Visser, Theo
6
Muckel, Eva
5
Schneider, Heiko
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All Publications
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2009: Bakhiya Nadiya; Arlt Volker M; Bahn Andrew; Burckhardt Gerhard; Phillips David H; Glatt Hansruedi
Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.
Toxicology 2009;264(1-2):74-9.
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2009: Bakhiya Nadiya; Monien Bernhard; Frank Heinz; Seidel Albrecht; Glatt Hansruedi
Renal organic anion transporters OAT1 and OAT3 mediate the cellular accumulation of 5-sulfooxymethylfurfural, a reactive, nephrotoxic metabolite of the Maillard product 5-hydroxymethylfurfural.
Biochemical pharmacology 2009;78(4):414-9.
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2009: Monien Bernhard H; Müller Carolin; Bakhiya Nadiya; Donath Claudia; Frank Heinz; Seidel Albrecht; Glatt Hansruedi
Probenecid, an inhibitor of transmembrane organic anion transporters, alters tissue distribution of DNA adducts in 1-hydroxymethylpyrene-treated rats.
Toxicology 2009;262(1):80-5.
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2009: Monien Bernhard H; Frank Heinz; Seidel Albrecht; Glatt Hansruedi
Conversion of the common food constituent 5-hydroxymethylfurfural into a mutagenic and carcinogenic sulfuric acid ester in the mouse in vivo.
Chemical research in toxicology 2009;22(6):1123-8.
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2009: Meinl Walter; Sczesny Silke; Brigelius-Flohé Regina; Blaut Michael; Glatt Hansruedi
Impact of gut microbiota on intestinal and hepatic levels of phase 2 xenobiotic-metabolizing enzymes in the rat.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(6):1179-86.
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2008: Monien Bernhard H; Müller Carolin; Engst Wolfram; Frank Heinz; Seidel Albrecht; Glatt Hansruedi
Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling.
Chemical research in toxicology 2008;21(10):2017-25.
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2008: Glatt Hansruedi; Rost Katharina; Frank Heinz; Seidel Albrecht; Kollock Ronny
Detoxification of promutagenic aldehydes derived from methylpyrenes by human aldehyde dehydrogenases ALDH2 and ALDH3A1.
Archives of biochemistry and biophysics 2008;477(2):196-205.
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2008: Liu Yungang; Glatt Hansruedi
Mutagenicity of N-nitrosodiethanolamine in a V79-derived cell line expressing two human biotransformation enzymes.
Mutation research 2008;643(1-2):64-9.
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2008: Meinl Walter; Donath Claudia; Schneider Heiko; Sommer Yasmin; Glatt Hansruedi
SULT1C3, an orphan sequence of the human genome, encodes an enzyme activating various promutagens.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(4):1249-56.
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2008: Hoelzl Christine; Glatt Hansruedi; Meinl Walter; Sontag Gerhard; Haidinger Gerald; Kundi Michael; Simic Tatjana; Chakraborty Asima; Bichler Julia; Ferk Franziska; Angelis Karel; Nersesyan Armen; Knasmüller Siegfried
Consumption of Brussels sprouts protects peripheral human lymphocytes against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and oxidative DNA-damage: results of a controlled human intervention trial.
Molecular nutrition & food research 2008;52(3):330-41.
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2008: Kollock Ronny; Frank Heinz; Seidel Albrecht; Meinl Walter; Glatt Hansruedi
Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenases.
Toxicology 2008;245(1-2):65-75.
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2008: Meinl Walter; Ebert Bettina; Glatt Hansruedi; Lampen Alfonso
Sulfotransferase forms expressed in human intestinal Caco-2 and TC7 cells at varying stages of differentiation and role in benzo[a]pyrene metabolism.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(2):276-83.
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2008: Kollock Ronny; Meinl Walter; Schneider Heiko; Batke Monika; Frank Heinz; Seidel Albrecht; Glatt Hansruedi
Efficient oxidation of promutagenic hydroxymethylpyrenes by cDNA-expressed human alcohol dehydrogenase ADH2 and its inhibition by various agents.
Biochemical pharmacology 2008;75(2):527-37.
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2007: Bakhiya Nadiya; Batke Monika; Laake Janet; Monien Bernhard H; Frank Heinz; Seidel Albrecht; Engst Wolfram; Glatt Hansruedi
Directing role of organic anion transporters in the excretion of mercapturic acids of alkylated polycyclic aromatic hydrocarbons.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(10):1824-31.
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2007: Arlt Volker M; Glatt Hansruedi; Gamboa da Costa Gonçalo; Reynisson Jóhannes; Takamura-Enya Takeji; Phillips David H
Mutagenicity and DNA adduct formation by the urban air pollutant 2-nitrobenzanthrone.
Toxicological sciences : an official journal of the Society of Toxicology 2007;98(2):445-57.
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2007: Geyer Joachim; Döring Barbara; Meerkamp Kerstin; Ugele Bernhard; Bakhiya Nadiya; Fernandes Carla F; Godoy José R; Glatt Hansruedi; Petzinger Ernst
Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6).
The Journal of biological chemistry 2007;282(27):19728-41.
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2007: Teubner Wera; Meinl Walter; Florian Simone; Kretzschmar Michael; Glatt Hansruedi
Identification and localization of soluble sulfotransferases in the human gastrointestinal tract.
The Biochemical journal 2007;404(2):207-15.
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2006: Blaut Michael; Braune Annett; Wunderlich Sandra; Sauer Patrick; Schneider Heiko; Glatt Hansruedi
Mutagenicity of arbutin in mammalian cells after activation by human intestinal bacteria.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(11):1940-7.
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2006: Bauer-Marinovic Morana; Florian Simone; Müller-Schmehl Katrin; Glatt Hansruedi; Jacobasch Gisela
Dietary resistant starch type 3 prevents tumor induction by 1,2-dimethylhydrazine and alters proliferation, apoptosis and dedifferentiation in rat colon.
Carcinogenesis 2006;27(9):1849-59.
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2006: Al-Buheissi Salah Z; Patel Hiten R; Meinl Walter; Hewer Alan; Bryan Richard L; Glatt Hansruedi; Miller Ronald A; Phillips David H
N-Acetyltransferase and sulfotransferase activity in human prostate: potential for carcinogen activation.
Pharmacogenetics and genomics 2006;16(6):391-9.
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2006: Bakhiya Nadiya; Stephani Monika; Bahn Andrew; Ugele Bernhard; Seidel Albrecht; Burckhardt Gerhard; Glatt Hansruedi
Uptake of chemically reactive, DNA-damaging sulfuric acid esters into renal cells by human organic anion transporters.
Journal of the American Society of Nephrology : JASN 2006;17(5):1414-21.
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2006: Sabbioni Gabriele; Jones Christopher R; Sepai Ovnair; Hirvonen Ari; Norppa Hannu; Järventaus Hilkka; Glatt Hansruedi; Pomplun Doreen; Yan Huifang; Brooks Lance R; Warren Sarah H; Demarini David M; Liu Yu-Ying
Biomarkers of exposure, effect, and susceptibility in workers exposed to nitrotoluenes.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(3):559-66.
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2006: Heine Tina; Glatt Hansruedi; Epe Bernd
Human cytochrome P450 reductase can act as a source of endogenous oxidative DNA damage and genetic instability.
Free radical biology & medicine 2006;40(5):801-7.
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2006: Meinl Walter; Pabel Ulrike; Osterloh-Quiroz Mandy; Hengstler Jan G; Glatt Hansruedi
Human sulphotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue.
International journal of cancer. Journal international du cancer 2006;118(5):1090-7.
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2005: Majer B J; Hofer E; Cavin C; Lhoste E; Uhl M; Glatt H R; Meinl W; Knasmüller S
Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2).
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(3):433-41.
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2005: Glatt Hansruedi; Schneider Heiko; Liu Yungang
V79-hCYP2E1-hSULT1A1, a cell line for the sensitive detection of genotoxic effects induced by carbohydrate pyrolysis products and other food-borne chemicals.
Mutation research 2005;580(1-2):41-52.
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2005: Moreno Victor; Glatt Hansruedi; Guino Elisabet; Fisher Eva; Meinl Walter; Navarro Matilde; Badosa Josep M; Boeing Heiner;
Polymorphisms in sulfotransferases SULT1A1 and SULT1A2 are not related to colorectal cancer.
International journal of cancer. Journal international du cancer 2005;113(4):683-6.
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2005: Glatt Hansruedi; Meinl Walter
Sulfotransferases and acetyltransferases in mutagenicity testing: technical aspects.
Methods in enzymology 2005;400():230-49.
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2004: Schwonbeck Susanne; Krause-Griep Andrea; Gajovic-Eichelmann Nenad; Ehrentreich-Förster Eva; Meinl Walter; Glatt Hansrüdi; Bier Frank F
Cohort analysis of a single nucleotide polymorphism on DNA chips.
Biosensors & bioelectronics 2004;20(5):956-66.
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2004: Schneider Heiko; Glatt Hansruedi
Sulpho-conjugation of ethanol in humans in vivo and by individual sulphotransferase forms in vitro.
The Biochemical journal 2004;383(Pt. 3):543-9.
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2004: Glatt Hansruedi; Meinl Walter
Use of genetically manipulated Salmonella typhimurium strains to evaluate the role of sulfotransferases and acetyltransferases in nitrofen mutagenicity.
Carcinogenesis 2004;25(5):779-86.
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2004: Glatt Hansruedi; Pabel Ulrike; Meinl Walter; Frederiksen Hanne; Frandsen Henrik; Muckel Eva
Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes.
Carcinogenesis 2004;25(5):801-7.
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2004: Majer B J; Kassie F; Sasaki Y; Pfau W; Glatt H; Meinl W; Darroudi F; Knasmüller S
Investigation of the genotoxic effects of 2-amino-9H-pyrido[2,3-b]indole in different organs of rodents and in human derived cells.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;802(1):167-73.
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2004: Glatt Hansruedi; Meinl Walter
Pharmacogenetics of soluble sulfotransferases (SULTs).
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(1):55-68.
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2003: Kester Monique H A; Kaptein Ellen; Roest Thirza J; van Dijk Caren H; Tibboel Dick; Meinl Walter; Glatt Hansruedi; Coughtrie Michael W H; Visser Theo J
Characterization of rat iodothyronine sulfotransferases.
American journal of physiology. Endocrinology and metabolism 2003;285(3):E592-8.
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2003: Arlt Volker M; Glatt Hansruedi; Muckel Eva; Pabel Ulrike; Sorg Bernd L; Seidel Albrecht; Frank Heinz; Schmeiser Heinz H; Phillips David H
Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells.
International journal of cancer. Journal international du cancer 2003;105(5):583-92.
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2003: Bernauer Ulrike; Glatt Hansruedi; Heinrich-Hirsch Barbara; Liu Yungang; Muckel Eva; Vieth Barbel; Gundert-Remy Ursula
Heterologous expression of mouse cytochrome P450 2e1 in V79 cells: construction and characterisation of the cell line and comparison with V79 cell lines stably expressing rat P450 2E1 and human P450 2E1.
Alternatives to laboratory animals : ATLA 2003;31(1):21-30.
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2003: Landes Nico; Pfluger Paul; Kluth Dirk; Birringer Marc; Rühl Ralph; Böl Gaby-Fleur; Glatt Hansruedi; Brigelius-Flohé Regina
Vitamin E activates gene expression via the pregnane X receptor.
Biochemical pharmacology 2003;65(2):269-73.
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2002: Meinl Walter; Meerman John H N; Glatt Hansruedi
Differential activation of promutagens by alloenzymes of human sulfotransferase 1A2 expressed in Salmonella typhimurium.
Pharmacogenetics 2002;12(9):677-89.
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2002: Edenharder R; Sager J W; Glatt H; Muckel E; Platt K L
Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2-acetylaminofluorene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in metabolically competent V79 cells.
Mutation research 2002;521(1-2):57-72.
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2002: Arlt Volker M; Glatt Hansruedi; Muckel Eva; Pabel Ulrike; Sorg Bernd L; Schmeiser Heinz H; Phillips David H
Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase.
Carcinogenesis 2002;23(11):1937-45.
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2002: Teubner Wera; Meinl Walter; Glatt Hansruedi
Stable expression of rat sulfotransferase 1B1 in V79 cells: activation of benzylic alcohols to mutagens.
Carcinogenesis 2002;23(11):1877-84.
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2002: Muckel E; Frandsen H; Glatt H R
Heterologous expression of human N-acetyltransferases 1 and 2 and sulfotransferase 1A1 in Salmonella typhimurium for mutagenicity testing of heterocyclic amines.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(8):1063-8.
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2002: Kester Monique H A; Bulduk Sema; van Toor Hans; Tibboel Dick; Meinl Walter; Glatt Hansruedi; Falany Charles N; Coughtrie Michael W H; Schuur A Gerlienke; Brouwer Abraham; Visser Theo J
Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters.
The Journal of clinical endocrinology and metabolism 2002;87(3):1142-50.
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2001: Meinl W; Glatt H
Structure and localization of the human SULT1B1 gene: neighborhood to SULT1E1 and a SULT1D pseudogene.
Biochemical and biophysical research communications 2001;288(4):855-62.
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2001: Glatt H; Boeing H; Engelke C E; Ma L; Kuhlow A; Pabel U; Pomplun D; Teubner W; Meinl W
Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects.
Mutation research 2001;482(1-2):27-40.
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2001: Pfau W; Knasmueller S; Glatt H R; Frandsen H; Alexander J; Murkovic M; Sontag G; Galceran T; Edenharder R; Skog K
Heterocyclic amines: human carcinogens in cooked food?
Nutrition, metabolism, and cardiovascular diseases : NMCD 2001;11(4 Suppl):82-6.
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2001: Williams J A; Stone E M; Fakis G; Johnson N; Cordell J A; Meinl W; Glatt H; Sim E; Phillips D H
N-Acetyltransferases, sulfotransferases and heterocyclic amine activation in the breast.
Pharmacogenetics 2001;11(5):373-88.
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2000: Davis W; Hewer A; Rajkowski K M; Meinl W; Glatt H; Phillips D H
Sex differences in the activation of tamoxifen to DNA binding species in rat liver in vivo and in rat hepatocytes in vitro: role of sulfotransferase induction.
Cancer research 2000;60(11):2887-91.
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2000: Kester M H; Bulduk S; Tibboel D; Meinl W; Glatt H; Falany C N; Coughtrie M W; Bergman A; Safe S H; Kuiper G G; Schuur A G; Brouwer A; Visser T J
Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs.
Endocrinology 2000;141(5):1897-900.
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2000: Engelke C E; Meinl W; Boeing H; Glatt H
Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2.
Pharmacogenetics 2000;10(2):163-9.
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2000: Glatt H; Engelke C E; Pabel U; Teubner W; Jones A L; Coughtrie M W; Andrae U; Falany C N; Meinl W
Sulfotransferases: genetics and role in toxicology.
Toxicology letters 2000;112-113():341-8.
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2000: Kreis P; Brandner S; Coughtrie M W; Pabel U; Meinl W; Glatt H; Andrae U
Human phenol sulfotransferases hP-PST and hM-PST activate propane 2-nitronate to a genotoxicant.
Carcinogenesis 2000;21(2):295-9.
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1999: Engst W; Landsiedel R; Hermersdörfer H; Doehmer J; Glatt H
Benzylic hydroxylation of 1-methylpyrene and 1-ethylpyrene by human and rat cytochromes P450 individually expressed in V79 Chinese hamster cells.
Carcinogenesis 1999;20(9):1777-85.
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1999: Kester M H; van Dijk C H; Tibboel D; Hood A M; Rose N J; Meinl W; Pabel U; Glatt H; Falany C N; Coughtrie M W; Visser T J
Sulfation of thyroid hormone by estrogen sulfotransferase.
The Journal of clinical endocrinology and metabolism 1999;84(7):2577-80.
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1999: Kester M H; Kaptein E; Roest T J; van Dijk C H; Tibboel D; Meinl W; Glatt H; Coughtrie M W; Visser T J
Characterization of human iodothyronine sulfotransferases.
The Journal of clinical endocrinology and metabolism 1999;84(4):1357-64.
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1999: Curto E V; Kwong C; Hermersdörfer H; Glatt H; Santis C; Virador V; Hearing V J; Dooley T P
Inhibitors of mammalian melanocyte tyrosinase: in vitro comparisons of alkyl esters of gentisic acid with other putative inhibitors.
Biochemical pharmacology 1999;57(6):663-72.
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1999: Andrae U; Kreis P; Coughtrie M W; Pabel U; Meinl W; Bartsch I; Glatt H
Activation of propane 2-nitronate to a genotoxicant in V79-derived cell lines engineered for the expression of rat hepatic sulfotransferases.
Mutation research 1999;439(2):191-7.
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1998: Seidel A; Friedberg T; Löllmann B; Schwierzok A; Funk M; Frank H; Holler R; Oesch F; Glatt H
Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 expressed in Chinese hamster V79 cells.
Carcinogenesis 1998;19(11):1975-81.
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1998: Glatt H; Davis W; Meinl W; Hermersdörfer H; Venitt S; Phillips D H
Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture.
Carcinogenesis 1998;19(10):1709-13.
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1998: Landsiedel R; Pabel U; Engst W; Ploschke J; Seidel A; Glatt H
Chiral inversion of 1-hydroxyethylpyrene enantiomers mediated by enantioselective sulfotransferases.
Biochemical and biophysical research communications 1998;247(1):181-5.
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1998: Visser T J; Kaptein E; Glatt H; Bartsch I; Hagen M; Coughtrie M W
Characterization of thyroid hormone sulfotransferases.
Chemico-biological interactions 1998;109(1-3):279-91.
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1998: Hagen M; Pabel U; Landsiedel R; Bartsch I; Falany C N; Glatt H
Expression of human estrogen sulfotransferase in Salmonella typhimurium: differences between hHST and hEST in the enantioselective activation of 1-hydroxyethylpyrene to a mutagen.
Chemico-biological interactions 1998;109(1-3):249-53.
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1998: Glatt H; Bartsch I; Christoph S; Coughtrie M W; Falany C N; Hagen M; Landsiedel R; Pabel U; Phillips D H; Seidel A; Yamazoe Y
Sulfotransferase-mediated activation of mutagens studied using heterologous expression systems.
Chemico-biological interactions 1998;109(1-3):195-219.
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1997: Luch A; Seidel A; Glatt H; Platt K L
Metabolic activation of the (+)-S,S- and (-)-R,R-enantiomers of trans-11,12-dihydroxy-11,12-dihydrodibenzo[a,l]pyrene: stereoselectivity, DNA adduct formation, and mutagenicity in Chinese hamster V79 cells.
Chemical research in toxicology 1997;10(10):1161-70.
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1997: Glatt H
Sulfation and sulfotransferases 4: bioactivation of mutagens via sulfation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(5):314-21.
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1995: Glatt H; Bartsch I; Czich A; Seidel A; Falany C N
Salmonella strains and mammalian cells genetically engineered for expression of sulfotransferases.
Toxicology letters 1995;82-83():829-34.
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1995: Sbrana I; Puliti A; Seidel A; Glatt H; Turchi G
Induction of chromosomal aberrations and spindle disturbances in Chinese hamster epithelial liver cells in culture by pyrene and benzo[a]pyrene quinones.
Mutagenesis 1995;10(6):505-12.
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1995: Glatt H; Pauly K; Czich A; Falany J L; Falany C N
Activation of benzylic alcohols to mutagens by rat and human sulfotransferases expressed in Escherichia coli.
European journal of pharmacology 1995;293(2):173-81.
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1994: Glatt H; Pauly K; Frank H; Seidel A; Oesch F; Harvey R G; Werle-Schneider G
Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases of the rat.
Carcinogenesis 1994;15(11):2605-11.
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1994: Luch A; Glatt H; Platt K L; Oesch F; Seidel A
Synthesis and mutagenicity of the diastereomeric fjord-region 11,12-dihydrodiol 13,14-epoxides of dibenzo[a,l]pyrene.
Carcinogenesis 1994;15(11):2507-16.
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1994: Oesch F; Oesch-Bartlomowicz B; Arens J; Fähndrich F; Vogel E; Friedberg T; Glatt H
Mechanism-based predictions of interactions.
Environmental health perspectives 1994;102 Suppl 9():5-9.
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1994: Glatt H; Seidel A; Oesch F; Gumbsch A
Fjord-region diol-epoxides of benzo[c]chrysene are potent inducers of micronuclei in murine bone marrow.
Mutation research 1994;309(1):37-43.
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1994: Glatt H
Comparison of common gene mutation tests in mammalian cells in culture: a position paper of the GUM Commission for the Development of Guidelines for Genotoxicity Testing.
Mutation research 1994;313(1):7-20.
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1994: Glatt H; Abu-Shqara E; Harvey R G; Blum J
Mutagenicity of K-region oxides and imines of chrysene, benzo[c]phenanthrene and benzo[g]chrysene in Salmonella typhimurium.
Mutation research 1994;308(2):135-41.
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1994: Glatt H; Staffa-Piée A; Enders N; Baidossi W; Blum J
The presence of KCl in the exposure medium strongly influences the mutagenicity of metabolites of polycyclic aromatic hydrocarbons in Escherichia coli.
Mutation research 1994;324(3):111-4.
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1994: Glatt H; Pauly K; Piée-Staffa A; Seidel A; Hornhardt S; Czich A
Activation of promutagens by endogenous and heterologous sulfotransferases expressed in continuous cell cultures.
Toxicology letters 1994;72(1-3):13-21.
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1994: Glatt H; Werle-Schneider G; Enders N; Monnerjahn S; Pudil J; Czich A; Seidel A; Schwarz M
1-Hydroxymethylpyrene and its sulfuric acid ester: toxicological effects in vitro and in vivo, and metabolic aspects.
Chemico-biological interactions 1994;92(1-3):305-19.
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1994: Glatt H; Abu-Shqara E; Martiné U; Baidossi W; Harvey R G; Blum J
K-region oxides and imines derived from alkylated benz[a]anthracene congeners: synthesis, stability in aqueous media and mutagenicity.
Mutagenesis 1994;9(2):83-92.
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1994: Friedberg T; Becker R; Oesch F; Glatt H
Studies on the importance of microsomal epoxide hydrolase in the detoxification of arene oxides using the heterologous expression of the enzyme in mammalian cells.
Carcinogenesis 1994;15(2):171-5.
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1993: Krämer A; Pudil J; Frank H; Oesch F; Glatt H
Some substrates and inhibitors of cytosolic epoxide hydrolase induce sister-chromatid exchanges in mammalian cells, but do not induce gene mutations in Salmonella typhimurium and V79 cells.
Mutation research 1993;290(2):165-74.
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1993: Werle-Schneider G; Schwarz M; Glatt H
Development of hydroxysteroid sulfotransferase-deficient lesions during hepatocarcinogenesis in rats.
Carcinogenesis 1993;14(11):2267-70.
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1993: Glatt H; Henschler R; Frank H; Seidel A; Yang C; Abu-Shqara E; Harvey R G
Sulfotransferase-mediated mutagenicity of 1-hydroxymethylpyrene and 4H-cyclopenta[def]chrysen-4-ol and its enhancement by chloride anions.
Carcinogenesis 1993;14(4):599-602.
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1993: Glatt H; Wameling C; Elsberg S; Thomas H; Marquardt H; Hewer A; Phillips D H; Oesch F; Seidel A
Genotoxicity characteristics of reverse diol-epoxides of chrysene.
Carcinogenesis 1993;14(1):11-9.
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1992: Glatt H; Anklam E; Robertson L W
Biphenyl and fluorinated derivatives: liver enzyme-mediated mutagenicity detected in Salmonella typhimurium and Chinese hamster V79 cells.
Mutation research 1992;281(3):151-6.
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1991: Krämer A; Frank H; Setiabudi F; Oesch F; Glatt H
Influence of the level of cytosolic epoxide hydrolase on the induction of sister chromatid exchanges by trans-beta-ethylstyrene 7,8-oxide in human lymphocytes.
Biochemical pharmacology 1991;42(11):2147-52.
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1991: Glatt H; Martiné U; Baidossi W; Blum J
Strong influence of the exposure medium on mutagenicity in the Ames test: 7-methylbenz[a]anthracene-5,6-oxide.
Mutagenesis 1991;6(6):537-40.
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1991: Glatt H; Piée A; Pauly K; Steinbrecher T; Schrode R; Oesch F; Seidel A
Fjord- and bay-region diol-epoxides investigated for stability, SOS induction in Escherichia coli, and mutagenicity in Salmonella typhimurium and mammalian cells.
Cancer research 1991;51(6):1659-67.
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1991: Oesch F; Gath I; Igarashi T; Glatt H; Oesch-Bartlomowicz B; Thomas H
Role of the well-known basic and recently discovered acidic glutathione S-transferases in the control of genotoxic metabolites.
Advances in experimental medicine and biology 1991;283():25-39.
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1991: Wölfel C; Platt K L; Dogra S; Glatt H; Wächter F; Doehmer J
Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of 17 beta-estradiol and 2-aminofluorene in V79 Chinese hamster cells.
Molecular carcinogenesis 1991;4(6):489-98.
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1990: Glatt H; Henschler R; Phillips D H; Blake J W; Steinberg P; Seidel A; Oesch F
Sulfotransferase-mediated chlorination of 1-hydroxymethylpyrene to a mutagen capable of penetrating indicator cells.
Environmental health perspectives 1990;88():43-8.
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1990: Glatt H; Gemperlein I; Setiabudi F; Platt K L; Oesch F
Expression of xenobiotic-metabolizing enzymes in propagatable cell cultures and induction of micronuclei by 13 compounds.
Mutagenesis 1990;5(3):241-9.
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1990: Glatt H; Witz G
Studies on the induction of gene mutations in bacterial and mammalian cells by the ring-opened benzene metabolites trans,trans-muconaldehyde and trans,trans-muconic acid.
Mutagenesis 1990;5(3):263-6.
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1990: Glatt H
Endogenous mutagens derived from amino acids.
Mutation research 1990;238(3):235-43.
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1990: Dogra S; Doehmer J; Glatt H; Mölders H; Siegert P; Friedberg T; Seidel A; Oesch F
Stable expression of rat cytochrome P-450IA1 cDNA in V79 Chinese hamster cells and their use in mutagenicity testing.
Molecular pharmacology 1990;37(5):608-13.
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1990: Glatt H; Utesch D; Herbst M; Oesch F
Mutagenicity experiments on L-cysteine and D-penicillamine using V79 cells as indicators and for metabolic activation.
Mutation research 1990;243(3):187-93.
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1990: Oesch F; Doehmer J; Friedberg T; Glatt H; Oesch-Bartlomowicz B; Platt K L; Steinberg P; Utesch D; Thomas H
Control of ultimate mutagenic species by diverse enzymes.
Progress in clinical and biological research 1990;340B():49-65.
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1989: Ludewig G; Dogra S; Glatt H
Genotoxicity of 1,4-benzoquinone and 1,4-naphthoquinone in relation to effects on glutathione and NAD(P)H levels in V79 cells.
Environmental health perspectives 1989;82():223-8.
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1989: Glatt H; Padykula R; Berchtold G A; Ludewig G; Platt K L; Klein J; Oesch F
Multiple activation pathways of benzene leading to products with varying genotoxic characteristics.
Environmental health perspectives 1989;82():81-9.
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1989: Glatt H
Mutagenicity spectra in Salmonella typhimurium strains of glutathione, L-cysteine and active oxygen species.
Mutagenesis 1989;4(3):221-7.
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1989: Glatt H; Harvey R G; Phillips D H; Hewer A; Grover P L
Influence of the alkyl substituent on mutagenicity and covalent DNA binding of bay region diol-epoxides of 7-methyl- and 7-ethylbenz(a)anthracene in Salmonella and V79 Chinese hamster cells.
Cancer research 1989;49(7):1778-82.
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1989: Doehmer J; Dogra S; Edigkaufer M; Molitor E; Siegert P; Friedberg T; Glatt H; Platt K; Seidel A; Thomas H
Introduction of cytochrome P-450 genes into V79 Chinese hamster cells to generate new mutagenicity test systems.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1989;13():164-8.
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1988: Doehmer J; Dogra S; Friedberg T; Monier S; Adesnik M; Glatt H; Oesch F
Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):5769-73.
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1988: Oesch F; Glatt H; Utesch D
Metabolic perspectives on in vitro toxicity tests.
Xenobiotica; the fate of foreign compounds in biological systems 1988;18 Suppl 1():35-44.
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1987: Glatt H; Seidel A; Ribeiro O; Kirkby C; Hirom P; Oesch F
Metabolic activation to a mutagen of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, a secondary metabolite of benzo[a]pyrene.
Carcinogenesis 1987;8(11):1621-7.
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1987: Utesch D; Glatt H; Oesch F
Rat hepatocyte-mediated bacterial mutagenicity in relation to the carcinogenic potency of benz(a)anthracene, benzo(a)pyrene, and twenty-five methylated derivatives.
Cancer research 1987;47(6):1509-15.
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1987: Glatt H; Gemperlein I; Turchi G; Heinritz H; Doehmer J; Oesch F
Search for cell culture systems with diverse xenobiotic-metabolizing activities and their use in toxicological studies.
Molecular toxicology 1987;1(4):313-34.
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1986: Glatt H; Oesch F; Neumann H G
V79 Chinese hamster cells deacetylate trans-N-acetoxy-4-acetylaminostilbene and trans-N-hydroxy-4-acetylaminostilbene to mutagenic and cytotoxic metabolites.
Cell biology and toxicology 1986;2(2):213-21.
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1986: Glatt H; Shtelzer S; Sheradsky T; Blum J; Oesch F
Mutagenicity of N-substituted phenanthrene 9,10-imines in Salmonella typhimurium and Chinese hamster V79 cells.
Environmental mutagenesis 1986;8(6):829-37.
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1985: Glatt H; Ludewig G; Platt K L; Waechter F; Yona I; Ben-Shoshan S; Jerushalmy P; Blum J; Oesch F
Arene imines, a new class of exceptionally potent mutagens in bacterial and mammalian cells.
Cancer research 1985;45(6):2600-7.
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