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Scott Gleim

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Alexander J Frey; Scott R Gleim; John Hwa; Salam Ibrahim; Emer M Smyth
Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif.
Raja Chakraborty; Rajinder P Bhullar; Shyamala Dakshinamurti; Scott R Gleim; John Hwa; Sai Prasad Pydi; Prashen Chelikani
New insights into structural determinants for prostanoid thromboxane A2 receptor- and prostacyclin receptor-G protein coupling.
Raja Chakraborty; Shyamala Dakshinamurti; Scott R Gleim; John Hwa; Sai Prasad Pydi; Prashen Chelikani
Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4.

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All Publications

2013: Alexander J Frey; Scott R Gleim; John Hwa; Salam Ibrahim; Emer M Smyth
Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif.
Journal of lipid research 2013;54(6):1678-90.
2013: Raja Chakraborty; Rajinder P Bhullar; Shyamala Dakshinamurti; Scott R Gleim; John Hwa; Sai Prasad Pydi; Prashen Chelikani
New insights into structural determinants for prostanoid thromboxane A2 receptor- and prostacyclin receptor-G protein coupling.
Molecular and cellular biology 2013;33(2):184-93.
2012: Raja Chakraborty; Shyamala Dakshinamurti; Scott R Gleim; John Hwa; Sai Prasad Pydi; Prashen Chelikani
Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4.
PloS one 2012;7(1):e29996.
2011: Jeremiah Stitham; Eric Arehart; Larkin Elderon; Scott R Gleim; Karen Douville; Zsolt Kasza; Kristina M Fetalvero; Todd Mackenzie; John Robb; Kathleen A Martin; John Hwa
Comprehensive biochemical analysis of rare prostacyclin receptor variants: study of association of signaling with coronary artery obstruction.
The Journal of biological chemistry 2011;286(9):7060-9.
2009: Scott R Gleim; Zsolt Kasza; Kathleen Martin; John Hwa
Prostacyclin receptor/thromboxane receptor interactions and cellular responses in human atherothrombotic disease.
Current atherosclerosis reports 2009;11(3):227-35.
2009: Kathleen A Martin; Scott R Gleim; Larkin Elderon; Kristina M Fetalvero; John Hwa
The human prostacyclin receptor from structure function to disease.
Progress in molecular biology and translational science 2009;89():133-66.
2008: Eric J Arehart; Jeremiah Stitham; Folkert Asselbergs; Karen Douville; Todd MacKenzie; Kristina M Fetalvero; Scott R Gleim; Zsolt Kasza; Yamini Rao; Laurie Martel; Sharon Segel; John Robb; Aaron Kaplan; Michael Simons; Richard J Powell; Jason Moore; Eric B Rimm; Kathleen A Martin; John Hwa
Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition.
Circulation research 2008;102(8):986-93.
2007: Jeremiah Stitham; Eric J Arehart; Scott R Gleim; N Li; Karen Douville; John Hwa
New insights into human prostacyclin receptor structure and function through natural and synthetic mutations of transmembrane charged residues.
British journal of pharmacology 2007;152(4):513-22.
2007: Jeremiah Stitham; Eric J Arehart; Scott R Gleim; Karen Douville; Todd Mackenzie; John Hwa
Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR).
Gene 2007;396(1):180-7.
2007: Eric J Arehart; Scott R Gleim; Z Kasza; Kristina M Fetalvero; Kathleen A Martin; John Hwa
Prostacyclin, atherothrombosis, and cardiovascular disease.
Current medicinal chemistry 2007;14(20):2161-9.
2007: Jeremiah Stitham; Eric J Arehart; Scott R Gleim; Karen Douville; John Hwa
Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations.
Prostaglandins & other lipid mediators 2007;82(1-4):95-108.
2006: Jeremiah Stitham; Scott R Gleim; Karen Douville; Eric J Arehart; John Hwa
Versatility and differential roles of cysteine residues in human prostacyclin receptor structure and function.
The Journal of biological chemistry 2006;281(48):37227-36.