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Laurie Glimcher

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Jin A Cho; Benedict C S Cross; Heidi De Luca; Edda Fiebiger; Brooke M Gardner; Laurie H Glimcher; Heather P Harding; Jonathan C Kagan; Ann-Hwee Lee; Phi Luong; Barbara Platzer; David Ron; Peter Walter; Wayne I Lencer
The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling.
Tae-Yoon Park; Jae-Hyuck Shim; Yoon-Chul Shin; Jong-Soon Lim; Inhee Mook-Jung; Tomohiro Morio; Eunji Cheong; Laurie H Glimcher; Fumiko Honda; Seung-Hyung Kim; Won-Ki Kim; Nae-Hyun Lee; Rae-Kyung Christina Lee; Sang-Kyou Lee
Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin.
Jae-Seon So; Margarite Tarrio; Andrew H Lichtman; Vera Ruda; Kevin Fitzgerald; Maria Frank-Kamenetsky; Laurie H Glimcher; Kyu Yeon Hur; Takao Iwawaki; Victor Koteliansky; Ann-Hwee Lee
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.

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2013: Jin A Cho; Benedict C S Cross; Heidi De Luca; Edda Fiebiger; Brooke M Gardner; Laurie H Glimcher; Heather P Harding; Jonathan C Kagan; Ann-Hwee Lee; Phi Luong; Barbara Platzer; David Ron; Peter Walter; Wayne I Lencer
The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling.
Cell host & microbe 2013;13(5):558-69.
2013: Tae-Yoon Park; Jae-Hyuck Shim; Yoon-Chul Shin; Jong-Soon Lim; Inhee Mook-Jung; Tomohiro Morio; Eunji Cheong; Laurie H Glimcher; Fumiko Honda; Seung-Hyung Kim; Won-Ki Kim; Nae-Hyun Lee; Rae-Kyung Christina Lee; Sang-Kyou Lee
Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin.
Journal of controlled release : official journal of the Controlled Release Society 2013;166(3):307-15.
2012: Jae-Seon So; Margarite Tarrio; Andrew H Lichtman; Vera Ruda; Kevin Fitzgerald; Maria Frank-Kamenetsky; Laurie H Glimcher; Kyu Yeon Hur; Takao Iwawaki; Victor Koteliansky; Ann-Hwee Lee
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.
Cell metabolism 2012;16(4):487-99.
2012: Joerg Ermann; Laurie H Glimcher
After GWAS: mice to the rescue?
Current opinion in immunology 2012;24(5):564-70.
2012: Marc N Wein; Antonios O Aliprantis; Ted S Gross; Dallas C Jones; Vanja Lazarevic; Sandra L Poliachik; Jae-Hyuck Shim; Rosalyn Sulyanto; Laurie H Glimcher
Control of bone resorption in mice by Schnurri-3.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(21):8173-8.
2012: Rene L Vidal; Craig Wirth; Benjamin Caballero; Felipe A Court; Ana Maria Cuervo; Alicia Figueroa; Laurie H Glimcher; Roberta Kiffin; Claudia Molina; Juan Segura-Aguilar; Peter Thielen; Claudio A Hetz
Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.
Human molecular genetics 2012;21(10):2245-62.
2012: Laurie H Glimcher; Olle Lindvall; Kiran Musunuru; Suzanne Topalian; Vince Aguirre; Anthony S Fauci
Translating research into therapies.
Cell 2012;148(6):1077-8.
2012: Matthew B Greenblatt; Robert Lafyatis; Jennifer L Sargent; Kelly Tsang; Michael L Whitfield; Giuseppina Farina; Laurie H Glimcher; Antonios O Aliprantis
Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets.
The American journal of pathology 2012;180(3):1080-94.
2012: Kyu Yeon Hur; Takao Iwawaki; Victor Koteliansky; Kevin Fitzgerald; Maria Frank-Kamenetsky; Laurie H Glimcher; Vera Ruda; Jae-Seon So; Ann-Hwee Lee
IRE1α activation protects mice against acetaminophen-induced hepatotoxicity.
The Journal of experimental medicine 2012;209(2):307-18.
2012: Yang Hu; Ann-Hwee Lee; Kyung Suk Park; Peter Thielen; Xin Wei; Liu Yang; Qiang Yang; Romain Cartoni; Dong Feng Chen; Kin-Sang Cho; Laurie H Glimcher; Zhigang He
Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells.
Neuron 2012;73(3):445-52.
2012: Christopher T Johansen; Sekar Kathiresan; Matthew Lanktree; Ann-Hwee Lee; Aldons J Lusis; Rebecca A Martins; Adam D McIntyre; Margarete Mehrabian; Miklós Péterfy; Jian Wang; Salim Yusuf; Sonia S Anand; Matthew R Ban; Henian Cao; Laurie H Glimcher; Murray W Huff; Robert A Hegele
Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia.
Circulation. Cardiovascular genetics 2012;5(1):66-72.
2012: Michael J Jurczak; Mario Kahn; Ann-Hwee Lee; Hui-Young Lee; Varman T Samuel; Andreas L Birkenfeld; Laurie H Glimcher; Blas A Guigni; François R Jornayvaz; Gerald I Shulman
Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice.
The Journal of biological chemistry 2012;287(4):2558-67.
2011: Weiguo Zou; Roland Baron; Nicholas Brady; Roger J Davis; Matthew B Greenblatt; Steven P Gygi; Dorothy Zhang Hu; Dallas Jones; Shashi Kant; Sutada Lotinun; Jae-Hyuck Shim; Bo Zhai; Laurie H Glimcher
MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice.
The Journal of clinical investigation 2011;121(11):4383-92.
2011: Claudio Hetz; Fabio Martinon; Diego Rodriguez; Laurie H Glimcher
The unfolded protein response: integrating stress signals through the stress sensor IRE1α.
Physiological reviews 2011;91(4):1219-43.
2011: David A Hess; Sean E Humphrey; Jeff Ishibashi; Barbara Damsz; Laurie H Glimcher; Ann-Hwee Lee; Stephen F Konieczny
Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice.
Gastroenterology 2011;141(4):1463-72.
2011: Dallas Jones; Laurie H Glimcher; Antonios O Aliprantis
Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection.
The Journal of clinical investigation 2011;121(7):2534-42.
2011: Vanja Lazarevic; Laurie H Glimcher
T-bet in disease.
Nature immunology 2011;12(7):597-606.
2011: Jung Hoon Lee; Jorge Plutzky; Jian Wang; Jonathan D Brown; Stephen A Duncan; Petros Giannikopoulos; Laurie H Glimcher; Robert A Hegele; Christopher T Johansen; Ann-Hwee Lee
The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism.
Nature medicine 2011;17(7):812-5.
2011: Ann-Hwee Lee; Keely Heidtman; Gökhan S Hotamisligil; Laurie H Glimcher
Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8885-90.
2011: Joerg Ermann; Wendy S Garrett; Juhi Kuchroo; Khadija Rourida; Jonathan N Glickman; Andre Bleich; Laurie H Glimcher
Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(17):7137-41.
2011: Tracy L Staton; Vanja Lazarevic; Dallas C Jones; Amanda J Lanser; Tsuyoshi Takagi; Shunsuke Ishii; Laurie H Glimcher
Dampening of death pathways by schnurri-2 is essential for T-cell development.
Nature 2011;472(7341):105-9.
2011: Claudio Hetz; Laurie H Glimcher
Protein homeostasis networks in physiology and disease.
Current opinion in cell biology 2011;23(2):123-5.
2011: Soledad Matus; Laurie H Glimcher; Claudio A Hetz
Protein folding stress in neurodegenerative diseases: a glimpse into the ER.
Current opinion in cell biology 2011;23(2):239-52.
2011: Laurie H Glimcher; Fabio Martinon; Robert L Modlin
Editorial overview.
Current opinion in immunology 2011;23(1):1-2.
2011: Fabio Martinon; Laurie H Glimcher
Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum.
Current opinion in immunology 2011;23(1):35-40.
2011: Weiguo Zou; Xi Chen; Jae-Hyuck Shim; Zhiwei Huang; Nicholas Brady; Dorothy Hu; Rebecca Drapp; Kirsten Sigrist; Laurie H Glimcher; Dallas Jones
The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid.
Nature cell biology 2011;13(1):59-65.
2011: Vanja Lazarevic; Xi Chen; Jae-Hyuck Shim; Eun-Sook Hwang; Eunjung Jang; Alexandra N Bolm; Mohamed Oukka; Vijay K Kuchroo; Laurie H Glimcher
T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt.
Nature immunology 2011;12(1):96-104.
2010: Won Jae Huh; Emel Esen; Jessica H Geahlen; Andrew J Bredemeyer; Ann-Hwee Lee; Guanglu Shi; Stephen F Konieczny; Laurie H Glimcher; Jason C Mills
XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum.
Gastroenterology 2010;139(6):2038-49.
2010: patrick veiga; Carey Ann Gallini; Chloé Beal; Monia Michaud; Mary L Delaney; Andrea DuBois; Artem Khlebnikov; Johan E T van Hylckama Vlieg; Shivesh Punit; Jonathan N Glickman; Andrew B Onderdonk; Laurie H Glimcher; Wendy S Garrett
Bifidobacterium animalis subsp. lactis fermented milk product reduces inflammation by altering a niche for colitogenic microbes.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(42):18132-7.
2010: Wendy S Garrett; Carey A Gallini; Tanya Yatsunenko; Monia Michaud; Andrea DuBois; Mary L Delaney; Shivesh Punit; Maria Karlsson; Lynn Bry; Jonathan N Glickman; Jeffrey I Gordon; Andrew B Onderdonk; Laurie H Glimcher
Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis.
Cell host & microbe 2010;8(3):292-300.
2010: Patrick L Collins; Shaojing Chang; Melodie Henderson; mohammed Soutto; Georgia M Davis; Allyson G McLoed; Michael J Townsend; Laurie H Glimcher; Douglas P Mortlock; Thomas M Aune
Distal regions of the human IFNG locus direct cell type-specific expression.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(3):1492-501.
2010: Matthew B Greenblatt; Jae-Hyuck Shim; Weiguo Zou; Despina Sitara; Michelle Schweitzer; Dorothy Hu; Sutada Lotinun; Yasuyo Sano; Roland Baron; Jin Mo Park; Simon Arthur; Min Xie; Michael D Schneider; Bo Zhai; Steven Gygi; Roger Davis; Laurie H Glimcher
The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice.
The Journal of clinical investigation 2010;120(7):2457-73.
2010: Matthew B Greenblatt; Antonios Aliprantis; Bella Hu; Laurie H Glimcher
Calcineurin regulates innate antifungal immunity in neutrophils.
The Journal of experimental medicine 2010;207(5):923-31.
2010: Dallas C Jones; Michelle N Schweitzer; Marc N Wein; Kirsten Sigrist; Tsuyoshi Takagi; Shunsuke Ishii; Laurie H Glimcher
Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(18):8254-8.
2010: Fabio Martinon; Xi Chen; Ann-Hwee Lee; Laurie H Glimcher
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.
Nature immunology 2010;11(5):411-8.
2010: Wendy S Garrett; Jeffrey I Gordon; Laurie H Glimcher
Homeostasis and inflammation in the intestine.
Cell 2010;140(6):859-70.
2010: Matthew B Greenblatt; Jae-Hyuck Shim; Laurie H Glimcher
TAK1 mediates BMP signaling in cartilage.
Annals of the New York Academy of Sciences 2010;1192():385-90.
2010: Ana C Anderson; Graham M Lord; Valerie Dardalhon; David H Lee; Catherine A Sabatos-Peyton; Laurie H Glimcher; Vijay K Kuchroo
T-bet, a Th1 transcription factor regulates the expression of Tim-3.
European journal of immunology 2010;40(3):859-66.
2010: John W Fathman; Michael F Gurish; Saskia Hemmers; Kevin Bonham; Daniel S Friend; Michael J Grusby; Laurie H Glimcher; Kerri A Mowen
NIP45 controls the magnitude of the type 2 T helper cell response.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3663-8.
2010: Lorena Riol-Blanco; Vanja Lazarevic; Amit Awasthi; Meike Mitsdoerffer; Brian S Wilson; Andy Croxford; Ari Waisman; Vijay K Kuchroo; Laurie H Glimcher; Mohamed Oukka
IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infections.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1710-20.
2010: Laurie H Glimcher
XBP1: the last two decades.
Annals of the rheumatic diseases 2010;69 Suppl 1():i67-71.
2010: Dallas C Jones; Laurie H Glimcher
Regulation of bone formation and immune cell development by Schnurri proteins.
Advances in experimental medicine and biology 2010;658():117-22.
2010: Antonios O Aliprantis; Laurie H Glimcher
NFATc1 in inflammatory and musculoskeletal conditions.
Advances in experimental medicine and biology 2010;658():69-75.
2009: Soledad Matus; Melissa Nassif; Laurie H Glimcher; Claudio A Hetz
XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy.
Autophagy 2009;5(8):1226-8.
2009: Richard G Jenner; Michael J Townsend; Ian Jackson; Kaiming Sun; Russell D Bouwman; Richard A Young; Laurie H Glimcher; Graham M Lord
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17876-81.
2009: Laurie H Glimcher
Reflections on health care.
The Journal of clinical investigation 2009;119(10):2858-9.
2009: Claudio A Hetz; Peter Thielen; Soledad Matus; Melissa Nassif; Felipe Court; Roberta Kiffin; Gabriela Martinez; Ana Maria Cuervo; Robert H Brown; Laurie H Glimcher
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy.
Genes & development 2009;23(19):2294-306.
2009: Wendy S Garrett; Laurie H Glimcher
T-bet-/- RAG2-/- ulcerative colitis: the role of T-bet as a peacekeeper of host-commensal relationships.
Cytokine 2009;48(1-2):144-7.
2009: Derrick J Todd; Louise J McHeyzer-Williams; Czeslawa Kowal; Ann-Hwee Lee; Bruce T Volpe; Betty Diamond; Michael G McHeyzer-Williams; Laurie H Glimcher
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development.
The Journal of experimental medicine 2009;206(10):2151-9.
2009: Claudio Hetz; Laurie H Glimcher
Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome.
Molecular cell 2009;35(5):551-61.
2009: Wendy S Garrett; Shivesh Punit; Carey A Gallini; Monia Michaud; Dorothy Zhang; Kirsten Sigrist; Graham M Lord; Jonathan N Glickman; Laurie H Glimcher
Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells.
Cancer cell 2009;16(3):208-19.
2009: Laurie H Glimcher; Ann-Hwee Lee
From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis.
Annals of the New York Academy of Sciences 2009;1173 Suppl 1():E2-9.
2009: Ann-Hwee Lee; Laurie H Glimcher
Intersection of the unfolded protein response and hepatic lipid metabolism.
Cellular and molecular life sciences : CMLS 2009;66(17):2835-50.
2009: Jae-Hyuck Shim; Matthew B Greenblatt; Min Xie; Michael D Schneider; Weiguo Zou; Bo Zhai; Steven Gygi; Laurie H Glimcher
TAK1 is an essential regulator of BMP signalling in cartilage.
The EMBO journal 2009;28(14):2028-41.
2009: Jonathan Esensten; Michael R Lee; Laurie H Glimcher; Jeffrey A Bluestone
T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):75-82.
2009: Xueli Yuan; Mohammed Javeed I Ansari; Francesca D'Addio; Jesus Paez-Cortez; Isabella Schmitt; Michela Donnarumma; Olaf Boenisch; Xiaozhi Zhao; Joyce Popoola; Michael R Clarkson; Hideo Yagita; Hisaya Akiba; Gordon J Freeman; John Iacomini; Laurence A Turka; Laurie H Glimcher; Mohamed H Sayegh
Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10734-9.
2009: Laurie H Glimcher; Judy Lieberman
Harvard's women four years later.
Nature immunology 2009;10(6):559-61.
2009: Roberto A Maldonado; Michelle A Soriano; L Carolina Perdomo; Kirsten Sigrist; Darrell J Irvine; Thomas Decker; Laurie H Glimcher
Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.
The Journal of experimental medicine 2009;206(4):877-92.
2009: Fernanda Lisbona; Diego Rojas-Rivera; Peter Thielen; Sebastian Zamorano; Derrick Todd; Fabio Martinon; Alvaro Glavic; Christina Kress; Jonathan H Lin; Peter Walter; John C Reed; Laurie H Glimcher; Claudio Hetz
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha.
Molecular cell 2009;33(6):679-91.
2009: Vanja Lazarevic; Alfred J Zullo; Michelle N Schweitzer; Tracy L Staton; Elena M Gallo; Gerald R Crabtree; Laurie H Glimcher
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells.
Nature immunology 2009;10(3):306-13.
2009: Jung Won Park; Hyun Jung Min; Jung Ho Sohn; Joo Young Kim; Jeong Ho Hong; Kirsten Sigrist; Laurie H Glimcher; Eun Sook Hwang
Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma.
The Journal of allergy and clinical immunology 2009;123(2):479-85.
2008: Jing Wu; Laurie H Glimcher; Antonios O Aliprantis
HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):16934-9.
2008: Antonios O Aliprantis; Yasuyoshi Ueki; Rosalyn Sulyanto; Arnold Park; Kirsten Sigrist; Sudarshana M Sharma; Michael C Ostrowski; Bjorn R Olsen; Laurie H Glimcher
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.
The Journal of clinical investigation 2008;118(11):3775-89.
2008: Arthur Kaser; Ann-Hwee Lee; Andre Franke; Jonathan N Glickman; Sebastian Zeissig; Herbert Tilg; Edward E S Nieuwenhuis; Darren E Higgins; Stefan Schreiber; Laurie H Glimcher; Richard S Blumberg
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.
Cell 2008;134(5):743-56.
2008: Derrich J Todd; Ann-Hwee Lee; Laurie H Glimcher
The endoplasmic reticulum stress response in immunity and autoimmunity.
Nature reviews. Immunology 2008;8(9):663-74.
2008: Miriam B F Werneck; Geanncarlo Lugo-Villarino; Eun Sook Hwang; Harvey Cantor; Laurie H Glimcher
T-bet plays a key role in NK-mediated control of melanoma metastatic disease.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8004-10.
2008: Ann-Hwee Lee; Erez F Scapa; David E Cohen; Laurie H Glimcher
Regulation of hepatic lipogenesis by the transcription factor XBP1.
Science (New York, N.Y.) 2008;320(5882):1492-6.
2008: Arthur O Tzianabos; Matthew A Holsti; Xin Xiao Zheng; Arthur F Stucchi; Vijay K Kuchroo; Terry B Strom; Laurie H Glimcher; William W Cruikshank
Functional Th1 cells are required for surgical adhesion formation in a murine model.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6970-6.
2008: Roman Karwot; Joachim H Maxeiner; Steffen Schmitt; Petra Scholtes; Michael Hausding; Hans A Lehr; Laurie H Glimcher; Susetta Finotto
Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model.
The Journal of allergy and clinical immunology 2008;121(4):992-9.e6.
2008: Siddhartha Mukherjee; Noopur Raje; Jesse A Schoonmaker; Julie C Liu; Teru Hideshima; Marc N Wein; Dallas C Jones; Sonia Vallet; Mary L Bouxsein; Samantha Pozzi; Shweta Chhetri; Y David Seo; Joshua P Aronson; Chirayu Patel; Mariateresa Fulciniti; Louise E Purton; Laurie H Glimcher; Jane B Lian; Gary Stein; Kenneth C Anderson; David T Scadden
Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice.
The Journal of clinical investigation 2008;118(2):491-504.
2008: Valerie Horsley; Antonios O Aliprantis; Lisa Polak; Laurie H Glimcher; Elaine Fuchs
NFATc1 balances quiescence and proliferation of skin stem cells.
Cell 2008;132(2):299-310.
2008: Claudio Hetz; Ann-Hwee Lee; Dennisse Gonzalez-Romero; Peter Thielen; Joaquin Castilla; Claudio Soto; Laurie H Glimcher
Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):757-62.
2008: Jyothi RENGARAJAN; Elissa Murphy; Arnold Park; Cassandra L Krone; Erik C Hett; Barry R Bloom; Laurie H Glimcher; Eric J Rubin
Mycobacterium tuberculosis Rv2224c modulates innate immune responses.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):264-9.
2008: Marc N Wein; Dallas C Jones; Laurie H Glimcher
Lentivirus delivery of shRNA constructs into osteoblasts.
Methods in molecular biology (Clifton, N.J.) 2008;455():149-55.
2007: Laurie H Glimcher; Dallas C Jones; Marc N Wein
Control of postnatal bone mass by the zinc finger adapter protein Schnurri-3.
Annals of the New York Academy of Sciences 2007;1116():174-81.
2007: Dallas C Jones; Marc N Wein; Laurie H Glimcher
Schnurri-3 is an essential regulator of osteoblast function and adult bone mass.
Annals of the rheumatic diseases 2007;66 Suppl 3():iii49-51.
2007: Wendy S Garrett; Graham M Lord; Shivesh Punit; Geanncarlo Lugo-Villarino; Sarkis K Mazmanian; Susumu Ito; Jonathan N Glickman; Laurie H Glimcher
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system.
Cell 2007;131(1):33-45.
2007: Neal N Iwakoshi; Marc Pypaert; Laurie H Glimcher
The transcription factor XBP-1 is essential for the development and survival of dendritic cells.
The Journal of experimental medicine 2007;204(10):2267-75.
2007: Adrian Erlebacher; Daniela Vencato; Kelly A Price; Dorothy Zhang; Laurie H Glimcher
Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus.
The Journal of clinical investigation 2007;117(5):1399-411.
2007: Laurie H Glimcher
Trawling for treasure: tales of T-bet.
Nature immunology 2007;8(5):448-50.
2007: Antonios O Aliprantis; Jingsong Wang; John W Fathman; Raphael Lemaire; David M Dorfman; Robert Lafyatis; Laurie H Glimcher
Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2827-30.
2007: Tatiana G Jones; Tatiana G Jones; Graham M Lord; Laurie H Glimcher; Jenny Hallgren; Yojiro Arinobu; Koichi Akashi; Alison M Paterson; Michael A Gurish; Francis W Luscinskas
Dendritic cell expression of the transcription factor T-bet regulates mast cell progenitor homing to mucosal tissue.
The Journal of experimental medicine 2007;204(2):431-9.
2007: Dallas C Jones; Marc N Wein; Laurie H Glimcher
Schnurri-3: a key regulator of postnatal skeletal remodeling.
Advances in experimental medicine and biology 2007;602():1-13.
2006: Viviany R Taqueti; Nir Grabie; Richard Colvin; Hong Pang; Petr Jarolim; Andrew D Luster; Laurie H Glimcher; Andrew H Lichtman
T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):5890-901.
2006: Fabio Martinon; Laurie H Glimcher
Gout: new insights into an old disease.
The Journal of clinical investigation 2006;116(8):2073-5.
2006: Lucia E Rosas; Heidi M Snider; Joseph Barbi; Anjali A Satoskar; Geanncarlo Lugo-Villarino; Tracy Keiser; Tracey L Papenfuss; Joan E Durbin; Danuta Radzioch; Laurie H Glimcher; Abhay R Satoskar
Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):22-5.
2006: Dallas C Jones; Marc N Wein; Mohamed Oukka; Jochen G Hofstaetter; Melvin J Glimcher; Laurie H Glimcher
Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.
Science (New York, N.Y.) 2006;312(5777):1223-7.
2006: Mari L Shinohara; Linrong Lu; Jing Bu; Miriam B F Werneck; Koichi Kobayashi; Laurie H Glimcher; Harvey Cantor
Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.
Nature immunology 2006;7(5):498-506.
2006: Claudio Hetz; Paula Bernasconi; Jill Fisher; Ann-Hwee Lee; Michael C Bassik; Bruno Antonsson; Gabriel S Brandt; Neal N Iwakoshi; Anna Schinzel; Laurie H Glimcher; Stanley J Korsmeyer
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.
Science (New York, N.Y.) 2006;312(5773):572-6.
2006: Boaz Tirosh; Neal N Iwakoshi; Laurie H Glimcher; Hidde L Ploegh
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response.
The Journal of biological chemistry 2006;281(9):5852-60.
2006: Jingsong Wang; John W Fathman; Geanncarlo Lugo-Villarino; Lucila Scimone; Ulrich H von Andrian; David M Dorfman; Laurie H Glimcher
Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells.
The Journal of clinical investigation 2006;116(2):414-21.
2006: Benjamin A Raby; Eun-Sook Hwang; Kristel van Steen; Kelan G Tantisira; Stanford Peng; Augusto A Litonjua; Ross Lazarus; Cosmas Giallourakis; John D Rioux; David Sparrow; Edwin K Silverman; Laurie H Glimcher; Scott Weiss
T-bet polymorphisms are associated with asthma and airway hyperresponsiveness.
American journal of respiratory and critical care medicine 2006;173(1):64-70.
2005: Ann-Hwee Lee; Gerald Chu; Neal N Iwakoshi; Laurie H Glimcher
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands.
The EMBO journal 2005;24(24):4368-80.
2005: Marc N Wein; Dallas C Jones; Laurie H Glimcher
Turning down the system: counter-regulatory mechanisms in bone and adaptive immunity.
Immunological reviews 2005;208():66-79.
2005: Mari L Shinohara; Marianne Jansson; Eun Sook Hwang; Miriam B F Werneck; Laurie H Glimcher; Harvey Cantor
T-bet-dependent expression of osteopontin contributes to T cell polarization.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(47):17101-6.
2005: Graham M Lord; Ravi M Rao; Hyeryun Choe; Brandon M Sullivan; Andrew H Lichtman; Francis W Luscinskas; Laurie H Glimcher
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.
Blood 2005;106(10):3432-9.
2005: Eun Sook Hwang; Jeong-Ho Hong; Laurie H Glimcher
IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.
The Journal of experimental medicine 2005;202(9):1289-300.
2005: Rajesh Ravindran; Joseph Foley; Thomas Stoklasek; Laurie H Glimcher; Stephen J McSorley
Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4603-10.
2005: Brandon M Sullivan; Ousman Jobe; Vanja Lazarevic; Kristine Vasquez; Roderick Bronson; Laurie H Glimcher; Igor Kramnik
Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4593-602.
2005: Geanncarlo Lugo-Villarino; Shu-Ichi Ito; Dennis M Klinman; Laurie H Glimcher
The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(37):13248-53.
2005: Boaz Tirosh; Neal N Iwakoshi; Laurie H Glimcher; Hidde L Ploegh
XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells.
The Journal of experimental medicine 2005;202(4):505-16.
2005: Susetta Finotto; Michael Hausding; Aysefa Doganci; Joachim H Maxeiner; Hans-Anton Lehr; Cornelia Luft; Peter R Galle; Laurie H Glimcher
Asthmatic changes in mice lacking T-bet are mediated by IL-13.
International immunology 2005;17(8):993-1007.
2005: Boaz Tirosh; Neal N Iwakoshi; Brendan N Lilley; Ann-Hwee Lee; Laurie H Glimcher; Hidde L Ploegh
Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products.
Journal of virology 2005;79(5):2768-79.
2005: Chiara Buono; Christoph J Binder; George Stavrakis; Joseph L Witztum; Laurie H Glimcher; Andrew H Lichtman
T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1596-601.
2005: Eun Sook Hwang; Susanne J Szabo; Pamela L Schwartzberg; Laurie H Glimcher
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
Science (New York, N.Y.) 2005;307(5708):430-3.
2005: David M Dorfman; Eun Sook Hwang; Aliakbar Shahsafaei; Laurie H Glimcher
T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma.
Human pathology 2005;36(1):10-5.
2004: Kelan G Tantisira; Eun Sook Hwang; Benjamin A Raby; Eric S Silverman; Stephen L Lake; Brent Richter; Stanford L Peng; Jeffrey M Drazen; Laurie H Glimcher; Scott Weiss
TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):18099-104.
2004: Kerri A Mowen; Laurie H Glimcher
Signaling pathways in Th2 development.
Immunological reviews 2004;202():203-22.
2004: Laurie H Glimcher; Michael J Townsend; Brandon M Sullivan; Graham M Lord
Recent developments in the transcriptional regulation of cytolytic effector cells.
Nature reviews. Immunology 2004;4(11):900-11.
2004: Adrian Erlebacher; Kelly A Price; Laurie H Glimcher
Maintenance of mouse trophoblast stem cell proliferation by TGF-beta/activin.
Developmental biology 2004;275(1):158-69.
2004: Umut Ozcan; Qiong Cao; Erkan Yilmaz; Ann-Hwee Lee; Neal N Iwakoshi; Esra Ozdelen; Gürol Tuncman; Cem Z Görgün; Laurie H Glimcher; Gökhan S Hotamisligil
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.
Science (New York, N.Y.) 2004;306(5695):457-61.
2004: Roberto A Maldonado; Darrell J Irvine; Robert Schreiber; Laurie H Glimcher
A role for the immunological synapse in lineage commitment of CD4 lymphocytes.
Nature 2004;431(7008):527-32.
2004: Lorenzo Romero-Ramirez; Hongbin Cao; Daniel Nelson; Ester Hammond; Ann-Hwee Lee; Hiderou Yoshida; Kazutoshi Mori; Laurie H Glimcher; Nicholas C Denko; Amato J Giaccia; Quynh-Thu Le; Albert C Koong
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.
Cancer research 2004;64(17):5943-7.
2004: Laurie H Glimcher
How we can help the next generation of scientists: introducing The "Hands-On" Primary Caregiver's Support Program.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):2891-2.
2004: Kerri A Mowen; Brandon T Schurter; John W Fathman; Michael David; Laurie H Glimcher
Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes.
Molecular cell 2004;15(4):559-71.
2004: David M Dorfman; Eun Sook Hwang; Aliakbar Shahsafaei; Laurie H Glimcher
T-bet, a T-cell-associated transcription factor, is expressed in a subset of B-cell lymphoproliferative disorders.
American journal of clinical pathology 2004;122(2):292-7.
2004: Estelle Bettelli; Brandon Sullivan; Susanne J Szabo; Raymond A Sobel; Laurie H Glimcher; Vijay K Kuchroo
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 2004;200(1):79-87.
2004: Arthur L Shaffer; Miriam Shapiro-Shelef; Neal N Iwakoshi; Ann-Hwee Lee; Shubing Qian; Hong Zhao; Xin Yu; Liming Yang; Bruce K Tan; Andreas Rosenwald; Elaine M Hurt; Emmanuel Petroulakis; Nahum Sonenberg; jon yewdell; Kathryn Calame; Laurie H Glimcher; Louis M Staudt
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation.
Immunity 2004;21(1):81-93.
2004: Adrian Erlebacher; Dorothy Zhang; Albert F Parlow; Laurie H Glimcher
Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system.
The Journal of clinical investigation 2004;114(1):39-48.
2004: Günther Lametschwandtner; Tilo Biedermann; Christoph Schwärzler; Claudia Günther; Julia Kund; Sandra Fassl; Sonja Hinteregger; Nicole Carballido-Perrig; Susanne J Szabo; Laurie H Glimcher; José M Carballido
Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities.
The Journal of allergy and clinical immunology 2004;113(5):987-94.
2004: Amy E Juedes; Evelyn Rodrigo; Lisa Togher; Laurie H Glimcher; Matthias G von Herrath
T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes.
The Journal of experimental medicine 2004;199(8):1153-62.
2004: Michael J Townsend; Amy S Weinmann; Jennifer L Matsuda; Rachelle Salomon; Peggy J Farnham; Christine A Biron; Laurent Gapin; Laurie H Glimcher
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.
Immunity 2004;20(4):477-94.
2004: Andrea J Gerth; Ling Lin; Markus F Neurath; Laurie H Glimcher; Stanford L Peng
An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells.
Gastroenterology 2004;126(4):1115-21.
2004: Stanford L Peng; Michael J Townsend; Jonathan L Hecht; Ian Alexander White; Laurie H Glimcher
T-bet regulates metastasis rate in a murine model of primary prostate cancer.
Cancer research 2004;64(2):452-5.
2004: Mohamed Oukka; Marc N Wein; Laurie H Glimcher
Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells.
The Journal of experimental medicine 2004;199(1):15-24.
2003: Brandon M Sullivan; Amy E Juedes; Susanne J Szabo; Matthias von Herrath; Laurie H Glimcher
Antigen-driven effector CD8 T cell function regulated by T-bet.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15818-23.
2003: David M Dorfman; Peter van den Elzen; Andrew P Weng; Aliakbar Shahsafaei; Laurie H Glimcher
Differential expression of T-bet, a T-box transcription factor required for Th1 T-cell development, in peripheral T-cell lymphomas.
American journal of clinical pathology 2003;120(6):866-73.
2003: Sung-Yun Pai; Morgan L Truitt; Chao-Nan Ting; Jeffrey M Leiden; Laurie H Glimcher; I-Cheng Ho
Critical roles for transcription factor GATA-3 in thymocyte development.
Immunity 2003;19(6):863-75.
2003: Evie Melanitou; Edwin Liu; Dongmei Miao; Liping Yu; Laurie H Glimcher; George S Eisenbarth
Absence of the T-bet gene coding for the Th1-related transcription factor does not affect diabetes-associated phenotypes in Balb/c mice.
Annals of the New York Academy of Sciences 2003;1005():187-91.
2003: Ann-Hwee Lee; Neal N Iwakoshi; Laurie H Glimcher
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response.
Molecular and cellular biology 2003;23(21):7448-59.
2003: Neal N Iwakoshi; Ann-Hwee Lee; Laurie H Glimcher
It's a good year for Blimp-1 (and plasma cells).
Immunity 2003;19(4):466-8.
2003: Helen E MacLean; James I Kim; Melvin J Glimcher; Jinxi Wang; Henry M Kronenberg; Laurie H Glimcher
Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development.
Developmental biology 2003;262(1):51-63.
2003: Ann-Hwee Lee; Neal N Iwakoshi; Kenneth C Anderson; Laurie H Glimcher
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9946-51.
2003: Neal N Iwakoshi; Ann-Hwee Lee; Laurie H Glimcher
The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response.
Immunological reviews 2003;194():29-38.
2003: Geanncarlo Lugo-Villarino; Roberto Maldonado-Lopez; Richard Possemato; Cristina Penaranda; Laurie H Glimcher
T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7749-54.
2003: Neal N Iwakoshi; Ann-Hwee Lee; Prasanth Vallabhajosyula; Kevin L Otipoby; Klaus Rajewsky; Laurie H Glimcher
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1.
Nature immunology 2003;4(4):321-9.
2003: Mary F Lyon; Robyn V Jamieson; Rahat Perveen; Peter H Glenister; Robert Griffiths; Yvonne Boyd; Laurie H Glimcher; Jack Favor; Francis L Munier; Graeme C M Black
A dominant mutation within the DNA-binding domain of the bZIP transcription factor Maf causes murine cataract and results in selective alteration in DNA binding.
Human molecular genetics 2003;12(6):585-94.
2003: Susanne J Szabo; Brandon M Sullivan; Stanford L Peng; Laurie H Glimcher
Molecular mechanisms regulating Th1 immune responses.
Annual review of immunology 2003;21():713-58.
2002: Adrian Erlebacher; Amanda K Lukens; Laurie H Glimcher
Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16940-5.
2002: Orly Avni; Dong Lee; Fernando Macian-Juan; Susanne J Szabo; Laurie H Glimcher; Anjana Rao
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.
Nature immunology 2002;3(7):643-51.
2002: Markus F Neurath; Susetta Finotto; Laurie H Glimcher
The role of Th1/Th2 polarization in mucosal immunity.
Nature medicine 2002;8(6):567-73.
2002: Markus F Neurath; Benno Weigmann; Susetta Finotto; J Glickman; Edward E S Nieuwenhuis; H Iijima; A Mizoguchi; E Mizoguchi; Jonas Mudter; Peter R Galle; A Bhan; Frank Autschbach; Brandon M Sullivan; Susanne J Szabo; Laurie H Glimcher; Richard S Blumberg
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease.
The Journal of experimental medicine 2002;195(9):1129-43.
2002: Stanford L Peng; Susanne J Szabo; Laurie H Glimcher
T-bet regulates IgG class switching and pathogenic autoantibody production.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5545-50.
2002: Jyothi RENGARAJAN; Kerri A Mowen; Kathryn D McBride; Erica D Smith; Harinder Singh; Laurie H Glimcher
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression.
The Journal of experimental medicine 2002;195(8):1003-12.
2002: I-Cheng Ho; Laurie H Glimcher
Transcription: tantalizing times for T cells.
Cell 2002;109 Suppl():S109-20.
2002: Zhinan Yin; ChangHung Chen; Susanne J Szabo; Laurie H Glimcher; Anuradha Ray; Joe Craft
T-Bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-gamma by gammadelta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1566-71.
2002: Susanne J Szabo; Brandon M Sullivan; Claudia Stemmann; Abhay R Satoskar; Barry P Sleckman; Laurie H Glimcher
Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells.
Science (New York, N.Y.) 2002;295(5553):338-42.
2002: Susetta Finotto; Markus F Neurath; Jonathan N Glickman; Shixin Qin; Hans-Anton Lehr; Francis H Y Green; Kate Ackerman; Kathleen Haley; Peter R Galle; Susanne J Szabo; Jeffrey M Drazen; George T De Sanctis; Laurie H Glimcher
Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet.
Science (New York, N.Y.) 2002;295(5553):336-8.
2002: Mohamed Oukka; Sean T Kim; Geancarlo Lugo; Jenny Sun; Lai-Chu Wu; Laurie H Glimcher
A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2.
Molecular cell 2002;9(1):121-31.
2002: Jyothi RENGARAJAN; Betty Tang; Laurie H Glimcher
NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells.
Nature immunology 2002;3(1):48-54.
2001: Laurie H Glimcher
Lineage commitment in lymphocytes: controlling the immune response.
The Journal of clinical investigation 2001;108(7):s25-s30.
2001: A M Reimold; Neal N Iwakoshi; J Manis; P Vallabhajosyula; E Szomolanyi-Tsuda; Ellen M Gravallese; D Friend; Michael J Grusby; F Alt; Laurie H Glimcher
Plasma cell differentiation requires the transcription factor XBP-1.
Nature 2001;412(6844):300-7.
2001: R Lieberson; Kerri A Mowen; K D McBride; V Leautaud; X Zhang; W K Suh; L Wu; Laurie H Glimcher
Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).
The Journal of experimental medicine 2001;194(1):89-98.
2001: I-Cheng Ho; Jonathan P Arm; Clifton O Bingham; Andrew Choi; K Frank Austen; Laurie H Glimcher
A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells.
The Journal of biological chemistry 2001;276(21):18321-6.
2001: Stanford L Peng; Andrea J Gerth; AM Ranger; Laurie H Glimcher
NFATc1 and NFATc2 together control both T and B cell activation and differentiation.
Immunity 2001;14(1):13-20.
2000: Jyothi RENGARAJAN; Susanne J Szabo; Laurie H Glimcher
Transcriptional regulation of Th1/Th2 polarization.
Immunology today 2000;21(10):479-83.
2000: Eunice Y Tsai; James V Falvo; Alla V Tsytsykova; Amy K Barczak; A M Reimold; Laurie H Glimcher; M J Fenton; D C Gordon; I F Dunn; Anne E Goldfeld
A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo.
Molecular and cellular biology 2000;20(16):6084-94.
2000: Laurie H Glimcher; K M Murphy
Lineage commitment in the immune system: the T helper lymphocyte grows up.
Genes & development 2000;14(14):1693-711.
2000: Susanne J Szabo; S T Kim; G L Costa; X Zhang; C G Fathman; Laurie H Glimcher
A novel transcription factor, T-bet, directs Th1 lineage commitment.
Cell 2000;100(6):655-69.
2000: Jyothi RENGARAJAN; Paul R Mittelstadt; Hans W Mages; Andrea J Gerth; Richard A Kroczek; Jonathan D Ashwell; Laurie H Glimcher
Sequential involvement of NFAT and Egr transcription factors in FasL regulation.
Immunity 2000;12(3):293-300.
2000: A M Reimold; A Etkin; I Clauss; A Perkins; D S Friend; J Zhang; Heidi F Horton; Alan L Scott; Stuart H Orkin; Michael C Byrne; M J Grusby; Laurie H Glimcher
An essential role in liver development for transcription factor XBP-1.
Genes & development 2000;14(2):152-7.
2000: AM Ranger; Louis C Gerstenfeld; J Wang; T Kon; Hyunsu Bae; Ellen M Gravallese; Melvin J Glimcher; Laurie H Glimcher
The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis.
The Journal of experimental medicine 2000;191(1):9-22.
1999: E S de Bont; CR Reilly; David Lo; Laurie H Glimcher; Tom Li Stephen
A minimal level of MHC class II expression is sufficient to abrogate autoreactivity.
International immunology 1999;11(8):1295-306.
1999: JI Kim; I-Cheng Ho; Michael J Grusby; Laurie H Glimcher
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines.
Immunity 1999;10(6):745-51.
1999: Tom Li Stephen; L Fan; Laurie H Glimcher
Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5078-84.
1999: JI Kim; T Li; I-Cheng Ho; Michael J Grusby; Laurie H Glimcher
Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3781-5.
1999: I-Cheng Ho; M H Kaplan; L Jackson-Grusby; Laurie H Glimcher; Michael J Grusby
Marking IL-4-producing cells by knock-in of the IL-4 gene.
International immunology 1999;11(2):243-7.
1999: Tom Li Stephen; Laurie H Glimcher; David Lo
Using thymus anatomy to dissect T cell repertoire selection.
Seminars in immunology 1999;11(1):65-70.
1999: Laurie H Glimcher; H Singh
Transcription factors in lymphocyte development--T and B cells get together.
Cell 1999;96(1):13-23.
1999: I-Cheng Ho; JI Kim; Susanne J Szabo; Laurie H Glimcher
Tissue-specific regulation of cytokine gene expression.
Cold Spring Harbor symposia on quantitative biology 1999;64():573-84.
1998: I-Cheng Ho; J H Kim; J W Rooney; Bruce M Spiegelman; Laurie H Glimcher
A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15537-41.
1998: I-Cheng Ho; David Lo; Laurie H Glimcher
c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms.
The Journal of experimental medicine 1998;188(10):1859-66.
1998: AM Ranger; Mohamed Oukka; Jyothi RENGARAJAN; Laurie H Glimcher
Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.
Immunity 1998;9(5):627-35.
1998: Mohamed Oukka; I-Cheng Ho; FC de la Brousse; Timothy Hoey; Michael J Grusby; Laurie H Glimcher
The transcription factor NFAT4 is involved in the generation and survival of T cells.
Immunity 1998;9(3):295-304.
1998: AM Ranger; Michael J Grusby; M R Hodge; Ellen M Gravallese; FC de la Brousse; Timothy Hoey; CS Mickanin; H Scott Baldwin; Laurie H Glimcher
The transcription factor NF-ATc is essential for cardiac valve formation.
Nature 1998;392(6672):186-90.
1998: M S Sabatine; Terri M Laufer; Laurie H Glimcher; M Widmer; H Winn; Hugh Auchincloss
Delayed rejection of soluble tumor necrosis factor receptor-secreting tumor allografts.
Transplantation 1998;65(1):113-20.
1998: AM Ranger; M R Hodge; Ellen M Gravallese; Mohamed Oukka; L Davidson; F W Alt; FC de la Brousse; Timothy Hoey; Michael J Grusby; Laurie H Glimcher
Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc.
Immunity 1998;8(1):125-34.
1997: Tom Li Stephen; ST Smiley; AM Ranger; Virginia K Clements; Suzanne Ostrand-Rosenberg; Laurie H Glimcher
Single amino acid mutations in the murine MHC class II A beta cytoplasmic domain abrogate antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):5914-20.
1997: Susanne J Szabo; Laurie H Glimcher; I-Cheng Ho
Genes that regulate interleukin-4 expression in T cells.
Current opinion in immunology 1997;9(6):776-81.
1997: J Douhan; R Lieberson; J H Knoll; H Zhou; Laurie H Glimcher
An isotype-specific activator of major histocompatibility complex (MHC) class II genes that is independent of class II transactivator.
The Journal of experimental medicine 1997;185(11):1885-95.
1997: H Zhou; H S Su; Xingmin Zhang; J Douhan; Laurie H Glimcher
CIITA-dependent and -independent class II MHC expression revealed by a dominant negative mutant.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4741-9.
1997: Richard S Lee; Michael J Grusby; Terri M Laufer; R Colvin; Laurie H Glimcher; Hugh Auchincloss
CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts.
Transplantation 1997;63(8):1123-33.
1996: M R Hodge; H J Chun; Jyothi RENGARAJAN; A Alt; R Lieberson; Laurie H Glimcher
NF-AT-Driven interleukin-4 transcription potentiated by NIP45.
Science (New York, N.Y.) 1996;274(5294):1903-5.
1996: J A Brown; Richard G Titus; N Nabavi; Laurie H Glimcher
Blockade of CD86 ameliorates Leishmania major infection by down-regulating the Th2 response.
The Journal of infectious diseases 1996;174(6):1303-8.
1996: AM Ranger; M P Das; Vijay K Kuchroo; Laurie H Glimcher
B7-2 (CD86) is essential for the development of IL-4-producing T cells.
International immunology 1996;8(10):1549-60.
1996: T M Laufer; J DeKoning; J S Markowitz; David Lo; Laurie H Glimcher
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex.
Nature 1996;383(6595):81-5.
1996: I-Cheng Ho; M R Hodge; J W Rooney; Laurie H Glimcher
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.
Cell 1996;85(7):973-83.
1996: I M Clauss; M Chu; J L Zhao; Laurie H Glimcher
The basic domain/leucine zipper protein hXBP-1 preferentially binds to and transactivates CRE-like sequences containing an ACGT core.
Nucleic acids research 1996;24(10):1855-64.
1996: S Baskar; Virginia K Clements; Laurie H Glimcher; N Nabavi; Suzanne Ostrand-Rosenberg
Rejection of MHC class II-transfected tumor cells requires induction of tumor-encoded B7-1 and/or B7-2 costimulatory molecules.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(10):3821-7.
1996: M R Hodge; AM Ranger; F Charles de la Brousse; Timothy Hoey; Michael J Grusby; Laurie H Glimcher
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice.
Immunity 1996;4(4):397-405.
1996: J Zhao; Gordon J Freeman; G S Gray; Lee M Nadler; Laurie H Glimcher
A cell type-specific enhancer in the human B7.1 gene regulated by NF-kappaB.
The Journal of experimental medicine 1996;183(3):777-89.
1996: J Douhan; I Hauber; M M Eibl; Laurie H Glimcher
Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D alpha and beta chains.
The Journal of experimental medicine 1996;183(3):1063-9.
1996: J Douhan; J A Brown; Z L Gleit; Chella S David; Laurie H Glimcher
Regulation of the E beta gene in vivo: lessons from E beta d transgenic mice.
International immunology 1996;8(2):255-65.
1996: D J Steele; T M Laufer; ST Smiley; Y Ando; Michael J Grusby; Laurie H Glimcher; Hugh Auchincloss
Two levels of help for B cell alloantibody production.
The Journal of experimental medicine 1996;183(2):699-703.
1996: A M Reimold; P D Ponath; Y S Li; R R Hardy; Chella S David; Jack L Strominger; Laurie H Glimcher
Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1.
The Journal of experimental medicine 1996;183(2):393-401.
1996: A M Reimold; Michael J Grusby; Bela Kosaras; J W Fries; R Mori; S Maniwa; I M Clauss; T Collins; Richard Sidman; M J Glimcher; Laurie H Glimcher
Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice.
Nature 1996;379(6562):262-5.
1996: ST Smiley; A Y Rudensky; Laurie H Glimcher; Michael J Grusby
Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):241-4.
1995: J W Rooney; Y L Sun; Laurie H Glimcher; Timothy Hoey
Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation.
Molecular and cellular biology 1995;15(11):6299-310.
1995: M R Hodge; J W Rooney; Laurie H Glimcher
The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(12):6397-405.
1995: H R Chakkalath; C M Theodos; J S Markowitz; Michael J Grusby; Laurie H Glimcher; Richard G Titus
Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease.
The Journal of infectious diseases 1995;171(5):1302-8.
1995: H Zhou; Laurie H Glimcher
Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency.
Immunity 1995;2(5):545-53.
1995: J W Rooney; Timothy Hoey; Laurie H Glimcher
Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene.
Immunity 1995;2(5):473-83.
1995: ST Smiley; T M Laufer; David Lo; Laurie H Glimcher; Michael J Grusby
Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation.
International immunology 1995;7(4):665-77.
1995: Vijay K Kuchroo; M P Das; J A Brown; AM Ranger; Scott S Zamvil; Raymond A Sobel; Howard L Weiner; N Nabavi; Laurie H Glimcher
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy.
Cell 1995;80(5):707-18.
1995: E M Ruderman; J S Kerr; S R Telford; Andrew Spielman; Laurie H Glimcher; Ellen M Gravallese
Early murine Lyme carditis has a macrophage predominance and is independent of major histocompatibility complex class II-CD4+ T cell interactions.
The Journal of infectious diseases 1995;171(2):362-70.
1995: S Baskar; Laurie H Glimcher; N Nabavi; Raymond T Jones; Suzanne Ostrand-Rosenberg
Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice.
The Journal of experimental medicine 1995;181(2):619-29.
1995: Michael J Grusby; Laurie H Glimcher
Immune responses in MHC class II-deficient mice.
Annual review of immunology 1995;13():417-35.
1994: A C Avery; J S Markowitz; Michael J Grusby; Laurie H Glimcher; Harvey Cantor
Activation of T cells by superantigen in class II-negative mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(11):4853-61.
1994: J M Darling; Laurie H Glimcher; S Shortkroff; B Albano; Ellen M Gravallese
Expression of metalloproteinases in pigmented villonodular synovitis.
Human pathology 1994;25(8):825-30.
1994: P Mombaerts; E Mizoguchi; H G Ljunggren; J Iacomini; H Ishikawa; L Wang; Michael J Grusby; Laurie H Glimcher; H J Winn; A K Bhan
Peripheral lymphoid development and function in TCR mutant mice.
International immunology 1994;6(7):1061-70.
1994: G P Linette; Michael J Grusby; S M Hedrick; T H Hansen; Laurie H Glimcher; Stanley J Korsmeyer
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points.
Immunity 1994;1(3):197-205.
1994: S Degermann; Charles D Surh; Laurie H Glimcher; Jonathan Sprent; David Lo
B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3254-63.
1994: R S Lee; Michael J Grusby; Laurie H Glimcher; H J Winn; Hugh Auchincloss
Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo.
The Journal of experimental medicine 1994;179(3):865-72.
1994: J W Rooney; M R Hodge; P G McCaffrey; Anjana Rao; Laurie H Glimcher
A common factor regulates both Th1- and Th2-specific cytokine gene expression.
The EMBO journal 1994;13(3):625-33.
1994: James A Lederer; J S Liou; M D Todd; Laurie H Glimcher; Andrew H Lichtman
Regulation of cytokine gene expression in T helper cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):77-86.
1994: Lionel B Ivashkiv; A Ayres; Laurie H Glimcher
Inhibition of IFN-gamma induction of class II MHC genes by cAMP and prostaglandins.
Immunopharmacology 1994;27(1):67-77.
1993: A L Crump; Michael J Grusby; Laurie H Glimcher; Harvey Cantor
Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10739-43.
1993: P Mombaerts; E Mizoguchi; Michael J Grusby; Laurie H Glimcher; A K Bhan; Susumu Tonegawa
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice.
Cell 1993;75(2):274-82.
1993: A M Reimold; C J Kara; J W Rooney; Laurie H Glimcher
Transforming growth factor beta 1 repression of the HLA-DR alpha gene is mediated by conserved proximal promoter elements.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(8):4173-82.
1993: S Baskar; N Nabavi; Laurie H Glimcher; Suzanne Ostrand-Rosenberg
Tumor cells expressing major histocompatibility complex class II and B7 activation molecules stimulate potent tumor-specific immunity.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(3):209-15.
1993: P D Ponath; D Fass; H C Liou; Laurie H Glimcher; Jack L Strominger
The regulatory gene, hXBP-1, and its target, HLA-DRA, utilize both common and distinct regulatory elements and protein complexes.
The Journal of biological chemistry 1993;268(23):17074-82.
1993: T M Laufer; M G von Herrath; Michael J Grusby; M B Oldstone; Laurie H Glimcher
Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice.
The Journal of experimental medicine 1993;178(2):589-96.
1993: S Baskar; Suzanne Ostrand-Rosenberg; N Nabavi; Lee M Nadler; Gordon J Freeman; Laurie H Glimcher
Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated major histocompatibility complex class II molecules.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5687-90.
1993: M D Todd; Michael J Grusby; James A Lederer; Elizabeth Lacy; Andrew H Lichtman; Laurie H Glimcher
Transcription of the interleukin 4 gene is regulated by multiple promoter elements.
The Journal of experimental medicine 1993;177(6):1663-74.
1993: C J Kara; Laurie H Glimcher
Developmental and cytokine-mediated regulation of MHC class II gene promoter occupancy in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(11):4934-42.
1993: A M Jevnikar; Gary G Singer; T Coffman; Laurie H Glimcher; V E Kelley
Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury.
Journal of the American Society of Nephrology : JASN 1993;3(12):1972-7.
1993: I M Clauss; Ellen M Gravallese; J M Darling; F Shapiro; M J Glimcher; Laurie H Glimcher
In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 1993;197(2):146-56.
1993: Michael J Grusby; Hugh Auchincloss; R Lee; R S Johnson; J P Spencer; M Zijlstra; Rudolf Jaenisch; V E Papaioannou; Laurie H Glimcher
Mice lacking major histocompatibility complex class I and class II molecules.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):3913-7.
1993: J S Markowitz; Hugh Auchincloss; Michael J Grusby; Laurie H Glimcher
Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2779-83.
1993: J S Markowitz; P R Rogers; Michael J Grusby; David Parker; Laurie H Glimcher
B lymphocyte development and activation independent of MHC class II expression.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(4):1223-33.
1993: A M Jevnikar; Gary G Singer; T Coffman; Laurie H Glimcher; V E Kelley
Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model.
Transplantation proceedings 1993;25(1 Pt 1):142-3.
1993: C J Kara; Laurie H Glimcher
Promoter accessibility within the environment of the MHC is affected in class II-deficient combined immunodeficiency.
The EMBO journal 1993;12(1):187-93.
1993: C J Kara; Laurie H Glimcher
Three in vivo promoter phenotypes in MHC class II deficient combined immunodeficiency.
Immunogenetics 1993;37(3):227-30.
1992: Lionel B Ivashkiv; M D Fleming; Laurie H Glimcher
Dominant negative mutants of transcription factor mXBP (CRE-BP1, ATF-2).
The New biologist 1992;4(4):360-8.
1992: Laurie H Glimcher; C J Kara
Sequences and factors: a guide to MHC class-II transcription.
Annual review of immunology 1992;10():13-49.
1991: Lionel B Ivashkiv; Laurie H Glimcher
Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements.
The Journal of experimental medicine 1991;174(6):1583-92.
1991: Ellen M Gravallese; J M Darling; Laurie H Glimcher; Mark Boothby
Role of lipopolysaccharide and IL-4 in control of transcription of the class II A alpha gene.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(7):2377-83.
1991: Michael J Grusby; R S Johnson; V E Papaioannou; Laurie H Glimcher
Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.
Science (New York, N.Y.) 1991;253(5026):1417-20.
1991: M Z Whitley; R Sisk; Lionel B Ivashkiv; Patricia W Finn; Laurie H Glimcher; Mark Boothby
Non-consensus DNA sequences function in a cell-type-specific enhancer of the mouse class II MHC gene A alpha.
International immunology 1991;3(9):877-88.
1991: Ellen M Gravallese; J M Darling; A L Ladd; Jeffrey N Katz; Laurie H Glimcher
In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium.
Arthritis and rheumatism 1991;34(9):1076-84.
1991: A M Jevnikar; Daniel C Brennan; Gary G Singer; J E Heng; Wlodzimierz Maslinski; R P Wuthrich; Laurie H Glimcher; V E Kelley
Stimulated kidney tubular epithelial cells express membrane associated and secreted TNF alpha.
Kidney international 1991;40(2):203-11.
1991: Patricia W Finn; C J Kara; Michael J Grusby; V Folsom; Laurie H Glimcher
Upstream elements of the MHC class II E beta gene active in B cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):4011-5.
1991: Santa Jeremy Ono; H C Liou; R Davidon; Jack L Strominger; Laurie H Glimcher
Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4309-12.
1991: C J Kara; Laurie H Glimcher
In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome.
Science (New York, N.Y.) 1991;252(5006):709-12.
1991: C J Kara; Laurie H Glimcher
Regulation of MHC class II gene transcription.
Current opinion in immunology 1991;3(1):16-21.
1991: A M Jevnikar; R P Wuthrich; Daniel C Brennan; Wlodzimierz Maslinski; Laurie H Glimcher; V E Rubin-Kelley
TNF-alpha is expressed on the surface of kidney proximal tubular cells.
Transplantation proceedings 1991;23(1 Pt 1):231-2.
1991: H C Liou; R Eddy; T Shows; B Lisowska-Grospierre; C Griscelli; C Doyle; J Mannhalter; M Eibl; Laurie H Glimcher
An HLA-DR alpha promoter DNA-binding protein is expressed ubiquitously and maps to human chromosomes 22 and 5.
Immunogenetics 1991;34(5):286-92.
1990: B Fontaine; M P Hanson; H C Liou; Laurie H Glimcher; G A Rouleau; James Gusella
BanI polymorphism at the XBP1 locus.
Nucleic acids research 1990;18(18):5578.
1990: Michael J Grusby; S C Mitchell; N Nabavi; Laurie H Glimcher
Casein expression in cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(17):6897-901.
1990: A M Jevnikar; R P Wuthrich; F Takei; H W Xu; Daniel C Brennan; Laurie H Glimcher; V E Rubin-Kelley
Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells.
Kidney international 1990;38(3):417-25.
1990: M J Grusby; S C Mitchell; Laurie H Glimcher
Molecular cloning of mouse cathepsin D.
Nucleic acids research 1990;18(13):4008.
1990: Patricia W Finn; T T Van; R S Accolla; Laurie H Glimcher
Loss of a DNA-protein complex correlates with extinguished major histocompatibility complex class II expression in a human B cell.
The Journal of experimental medicine 1990;171(6):2159-64.
1990: Patricia W Finn; C J Kara; T T Van; J Douhan; Mark Boothby; Laurie H Glimcher
The presence of a DNA binding complex correlates with E beta class II MHC gene expression.
The EMBO journal 1990;9(5):1543-9.
1990: C J Kara; H C Liou; Lionel B Ivashkiv; Laurie H Glimcher
A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain.
Molecular and cellular biology 1990;10(4):1347-57.
1990: Lionel B Ivashkiv; H C Liou; C J Kara; W W Lamph; Inder M Verma; Laurie H Glimcher
mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.
Molecular and cellular biology 1990;10(4):1609-21.
1990: H C Liou; Mark Boothby; Patricia W Finn; R Davidon; N Nabavi; N J Zeleznik-Le; Jenny P-Y Ting; Laurie H Glimcher
A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter.
Science (New York, N.Y.) 1990;247(4950):1581-4.
1990: Michael J Grusby; N Nabavi; H Wong; R F Dick; J A Bluestone; M C Schotz; Laurie H Glimcher
Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase.
Cell 1990;60(3):451-9.
1990: R P Wuthrich; Laurie H Glimcher; M A Yui; A M Jevnikar; S E Dumas; V E Kelley
MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells.
Kidney international 1990;37(2):783-92.
1990: Patricia W Finn; C J Kara; J Douhan; T T Van; V Folsom; Laurie H Glimcher
Interferon gamma regulates binding of two nuclear protein complexes in a macrophage cell line.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):914-8.
1990: R P Wuthrich; A M Jevnikar; F Takei; Laurie H Glimcher; V E Kelley
Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis.
The American journal of pathology 1990;136(2):441-50.
1990: Mark Boothby; H C Liou; Patricia W Finn; Ellen M Gravallese; Laurie H Glimcher
Control of transcription at the murine A alpha locus.
Immunologic research 1990;9(2):77-92.
1990: N Nabavi; Michael J Grusby; Patricia W Finn; D J Wolgemuth; Laurie H Glimcher
Identification of an IL-4-inducible gene expressed in differentiating lymphocytes and male germ cells.
Developmental immunology 1990;1(1):19-30.
1989: Z Ghogawala; E Choi; K R Daly; L R Blanco; I J Griffith; Laurie H Glimcher
An intronic 10-base-pair deletion in a class II A beta gene affects RNA processing.
Molecular and cellular biology 1989;9(10):4402-8.
1989: Ellen M Gravallese; Mark Boothby; Cynthia M Smas; Laurie H Glimcher
A lipopolysaccharide-induced DNA-binding protein for a class II gene in B cells is distinct from NF-kappa B.
Molecular and cellular biology 1989;9(8):3184-92.
1989: Y St-Pierre; N Nabavi; Z Ghogawala; Laurie H Glimcher; Tania H Watts
A functional role for signal transduction via the cytoplasmic domains of MHC class II proteins.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(3):808-12.
1989: N A Johnson; F Carland; P M Allen; Laurie H Glimcher
T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3298-304.
1989: N Nabavi; Z Ghogawala; A Myer; I J Griffith; William F Wade; Z Z Chen; David J McKean; Laurie H Glimcher
Antigen presentation abrogated in cells expressing truncated Ia molecules.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(5):1444-7.
1989: Mark Boothby; H C Liou; Laurie H Glimcher
Differences in DNA sequence specificity among MHC class II X box binding proteins.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(3):1005-14.
1989: R P Wuthrich; M A Yui; G Mazoujian; N Nabavi; Laurie H Glimcher; V E Kelley
Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MRL/lpr mice with lupus nephritis.
The American journal of pathology 1989;134(1):45-51.
1988: Mark Boothby; Ellen M Gravallese; H C Liou; Laurie H Glimcher
A DNA binding protein regulated by IL-4 and by differentiation in B cells.
Science (New York, N.Y.) 1988;242(4885):1559-62.
1988: H C Liou; Mark Boothby; Laurie H Glimcher
Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element.
Science (New York, N.Y.) 1988;242(4875):69-71.
1988: I J Griffith; Z Ghogawala; N Nabavi; David E Golan; A Myer; David J McKean; Laurie H Glimcher
Cytoplasmic domain affects membrane expression and function of an Ia molecule.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4847-51.
1988: H C Liou; B S Polla; D Aragnol; L D Leserman; I J Griffith; Laurie H Glimcher
A tissue-specific DNase I-hypersensitive site in a class II A alpha gene is under trans-regulatory control.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2738-42.
1988: I J Griffith; N Nabavi; Z Ghogawala; C G Chase; M Rodriguez; David J McKean; Laurie H Glimcher
Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules.
The Journal of experimental medicine 1988;167(2):541-55.
1988: B S Polla; J Ohara; William Paul; N Nabavi; A Myer; H C Liou; F W Shen; S Gillis; J V Bonventre; Laurie H Glimcher
Differential induction of class II gene expression in murine pre-B-cell lines by B-cell stimulatory factor-1 and by antibodies to B-cell surface antigens.
The Journal of molecular and cellular immunology : JMCI 1988;3(6):363-73.