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Joseph Glorioso

Research Profile

Chemicals & Drugs

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TOP 3
Hiroaki Uchida; Ji Young Yoo; Hyunjung Baek; Janet Chan; E Antonio Chiocca; Justus B Cohen; William F Goins; Paola Grandi; Amy Haseley; Chang-Sook Hong; Balveen Kaur; Izumi Kumagai; Masahide Kuroki; Heechung Kwon; Marco Marzulli; Lucia Mazzacurati; Kenji Nakano; Hiroshi Nakashima; Joseph C Glorioso
Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Hitoshi Yokoyama; William C de Groat; Joseph C Glorioso; William F Goins; James R Goss; David M Krisky; Osamu Nishizawa; Tomohiko Oguchi; Darren Wolfe; Naoki Yoshimura
Effects of herpes simplex virus vector-mediated enkephalin gene therapy on bladder overactivity and nociception.
Yasuhito Funahashi; Joseph C Glorioso; William F Goins; James R Goss; Momokazu Gotoh; Tomohiko Oguchi; Pradeep Tyagi; Naoki Yoshimura
Herpes simplex virus vector mediated gene therapy of tumor necrosis factor-α blockade for bladder overactivity and nociception in rats.

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All Publications

2013: Hiroaki Uchida; Ji Young Yoo; Hyunjung Baek; Janet Chan; E Antonio Chiocca; Justus B Cohen; William F Goins; Paola Grandi; Amy Haseley; Chang-Sook Hong; Balveen Kaur; Izumi Kumagai; Masahide Kuroki; Heechung Kwon; Marco Marzulli; Lucia Mazzacurati; Kenji Nakano; Hiroshi Nakashima; Joseph C Glorioso
Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(3):561-9.
2013: Hitoshi Yokoyama; William C de Groat; Joseph C Glorioso; William F Goins; James R Goss; David M Krisky; Osamu Nishizawa; Tomohiko Oguchi; Darren Wolfe; Naoki Yoshimura
Effects of herpes simplex virus vector-mediated enkephalin gene therapy on bladder overactivity and nociception.
Human gene therapy 2013;24(2):170-80.
2013: Yasuhito Funahashi; Joseph C Glorioso; William F Goins; James R Goss; Momokazu Gotoh; Tomohiko Oguchi; Pradeep Tyagi; Naoki Yoshimura
Herpes simplex virus vector mediated gene therapy of tumor necrosis factor-α blockade for bladder overactivity and nociception in rats.
The Journal of urology 2013;189(1):366-73.
2012: Xiaodong Zhu; Jonathan Bortinger; David Fischer; Gregory Gibson; Joseph C Glorioso; Dustin Letts; Michael A Mathier; Kenneth McCurry; Charles F McTiernan; Navin Rajagopalan; Hemal Shah; Yoshiya Toyoda; Wenyu Xiang; Barry London
Immunosuppression decreases inflammation and increases AAV6-hSERCA2a-mediated SERCA2a expression.
Human gene therapy 2012;23(7):722-32.
2012: Kathleen M Salerno; Pamela K Cornuet; Charlotte M Diges; Joseph C Glorioso; Xiaotang Jing; Kathryn M Albers
Sox11 modulates brain-derived neurotrophic factor expression in an exon promoter-specific manner.
Journal of neuroscience research 2012;90(5):1011-9.
2012: Bonnie Reinhart; Justus B Cohen; Junichi Eguchi; Wendy Fellows; Adriana Forero; Joseph C Glorioso; Chang-Sook Hong; Lucia Mazzacurati; Ajay Niranjan; Hideho Okada; Paola Grandi
Inhibition of Indoleamine-2,3-dioxygenase (IDO) in Glioblastoma Cells by Oncolytic Herpes Simplex Virus.
Advances in virology 2012;2012():815465.
2012: Xiaotang Jing; Ting Wang; Joseph C Glorioso; Shaohua Huang; Kathryn M Albers
The transcription factor Sox11 promotes nerve regeneration through activation of the regeneration-associated gene Sprr1a.
Experimental neurology 2012;233(1):221-32.
2011: David J Fink; Joseph C Glorioso; James Goss; David M Krisky; Marina Mata; James B Wechuck; Darren Wolfe
Gene therapy for pain: results of a phase I clinical trial.
Annals of neurology 2011;70(2):207-12.
2011: James R Goss; Norma Arbujas; Joseph C Glorioso; Paul D Robbins; Andria Rasile Robinson; Donna Beer Stolz; Mingdi Zhang; Laura J Niedernhofer
Premature aging-related peripheral neuropathy in a mouse model of progeria.
Mechanisms of ageing and development 2011;132(8-9):437-42.
2011: Paula Bernal; Eileen M Bauer; Rong Cao; Salony Maniar; Mackenzie Mosher; Jun Chen; Qiming Jane Wang; Joseph C Glorioso; Bruce R Pitt; Simon C Watkins; Claudette M St Croix
A role for zinc in regulating hypoxia-induced contractile events in pulmonary endothelium.
American journal of physiology. Lung cellular and molecular physiology 2011;300(6):L874-86.
2011: William F Goins; David M Krisky; James B Wechuck; Darren Wolfe; Shaohua Huang; Joseph C Glorioso
Generation of replication-competent and -defective HSV vectors.
Cold Spring Harbor protocols 2011;2011(5):pdb.prot5615.
2011: James R Goss; Michael Cascio; William F Goins; Shaohua Huang; David M Krisky; Richard J Clarke; Jon W Johnson; Hitoshi Yokoyama; Naoki Yoshimura; Michael S Gold; Joseph C Glorioso
HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(3):500-6.
2011: Laura J Niedernhofer; Joseph C Glorioso; Paul D Robbins
Dedifferentiation rescues senescence of progeria cells but only while pluripotent.
Stem cell research & therapy 2011;2(3):28.
2010: Hiroaki Uchida; Janet Chan; William F Goins; Paola Grandi; Izumi Kumagai; Justus B Cohen; Joseph C Glorioso
A double mutation in glycoprotein gB compensates for ineffective gD-dependent initiation of herpes simplex virus type 1 infection.
Journal of virology 2010;84(23):12200-9.
2010: Chang-Sook Hong; Wendy Fellows; Ajay Niranjan; Sean Alber; simon simon watkins; Justus B Cohen; Joseph C Glorioso; P Grandi
Ectopic matrix metalloproteinase-9 expression in human brain tumor cells enhances oncolytic HSV vector infection.
Gene therapy 2010;17(10):1200-5.
2010: Minoru Miyazato; Kimio Sugaya; Seiichi Saito; Michael B Chancellor; William F Goins; James R Goss; william chesney de groat; Joseph C Glorioso; Naoki Yoshimura
Suppression of detrusor-sphincter dyssynergia by herpes simplex virus vector mediated gene delivery of glutamic acid decarboxylase in spinal cord injured rats.
The Journal of urology 2010;184(3):1204-10.
2010: Naoki Yoshimura; Ryuichi Kato; Michael B Chancellor; Joel B Nelson; Joseph C Glorioso
Gene therapy as future treatment of erectile dysfunction.
Expert opinion on biological therapy 2010;10(9):1305-14.
2010: Darren Wolfe; April M Craft; Justus B Cohen; Joseph C Glorioso
A herpes simplex virus vector system for expression of complex cellular cDNA libraries.
Journal of virology 2010;84(14):7360-8.
2010: Arthur R Frampton; Hiroaki Uchida; Jens von Einem; William F Goins; Paola Grandi; Justus B Cohen; Nikolaus Osterrieder; Joseph C Glorioso
Equine herpesvirus type 1 (EHV-1) utilizes microtubules, dynein, and ROCK1 to productively infect cells.
Veterinary microbiology 2010;141(1-2):12-21.
2009: James R Goss; M S Gold; Joseph C Glorioso
HSV vector-mediated modification of primary nociceptor afferents: an approach to inhibit chronic pain.
Gene therapy 2009;16(4):493-501.
2009: Paola Grandi; Pierpaolo Peruzzi; Bonnie Reinhart; Justus B Cohen; E Antonio Chiocca; Joseph C Glorioso
Design and application of oncolytic HSV vectors for glioblastoma therapy.
Expert review of neurotherapeutics 2009;9(4):505-17.
2009: William F Goins; James R Goss; Michael B Chancellor; william chesney de groat; Joseph C Glorioso; Naoki Yoshimura
Herpes simplex virus vector-mediated gene delivery for the treatment of lower urinary tract pain.
Gene therapy 2009;16(4):558-69.
2009: Hiroaki Uchida; Waris A Shah; Ali Ozuer; Arthur R Frampton; William F Goins; Paola Grandi; Justus B Cohen; Joseph C Glorioso
Generation of herpesvirus entry mediator (HVEM)-restricted herpes simplex virus type 1 mutant viruses: resistance of HVEM-expressing cells and identification of mutations that rescue nectin-1 recognition.
Journal of virology 2009;83(7):2951-61.
2009: Kyle G Grant; David M Krisky; Mohammad M Ataai; Joseph C Glorioso
Engineering cell lines for production of replication defective HSV-1 gene therapy vectors.
Biotechnology and bioengineering 2009;102(4):1087-97.
2009: Hitoshi Yokoyama; Katsumi Sasaki; Michael E Franks; William F Goins; James R Goss; william chesney de groat; Joseph C Glorioso; Michael B Chancellor; Naoki Yoshimura
Gene therapy for bladder overactivity and nociception with herpes simplex virus vectors expressing preproenkephalin.
Human gene therapy 2009;20(1):63-71.
2009: Joseph C Glorioso; David J Fink
Herpes vector-mediated gene transfer in the treatment of chronic pain.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(1):13-8.
2009: R Kato; Darren Wolfe; C H Coyle; James B Wechuck; P Tyagi; T Tsukamoto; Joel B Nelson; Joseph C Glorioso; Michael B Chancellor; Naoki Yoshimura
Herpes simplex virus vector-mediated delivery of neurturin rescues erectile dysfunction of cavernous nerve injury.
Gene therapy 2009;16(1):26-33.
2008: Rahul Srinivasan; Darren Wolfe; James Goss; simon simon watkins; william chesney de groat; Adrian Sculptoreanu; Joseph C Glorioso
Protein kinase C epsilon contributes to basal and sensitizing responses of TRPV1 to capsaicin in rat dorsal root ganglion neurons.
The European journal of neuroscience 2008;28(7):1241-54.
2008: Rahul Srinivasan; David J Fink; Joseph C Glorioso
HSV vectors for gene therapy of chronic pain.
Current opinion in molecular therapeutics 2008;10(5):449-55.
2008: Han Li; Rajasekaran Baskaran; David M Krisky; Kiflai Bein; Paola Grandi; Justus B Cohen; Joseph C Glorioso
Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growth.
Virology 2008;375(1):13-23.
2008: William F Goins; David M Krisky; James B Wechuck; Shaohua Huang; Joseph C Glorioso
Construction and production of recombinant herpes simplex virus vectors.
Methods in molecular biology (Clifton, N.J.) 2008;433():97-113.
2007: Darren Wolfe; Shuanglin Hao; Jian Hu; Rahul Srinivasan; James Goss; Marina Mata; David J Fink; Joseph C Glorioso
Engineering an endomorphin-2 gene for use in neuropathic pain therapy.
Pain 2007;133(1-3):29-38.
2007: Charles F McTiernan; Michael A Mathier; Xiaodong Zhu; Xiao Xiao; E Klein; C H Swan; Haider Mehdi; G Gibson; Anita M Trichel; Joseph C Glorioso; Arthur M Feldman; K R McCurry; Barry London
Myocarditis following adeno-associated viral gene expression of human soluble TNF receptor (TNFRII-Fc) in baboon hearts.
Gene therapy 2007;14(23):1613-22.
2007: Arthur R Frampton; Donna B Stolz; Hiroaki Uchida; William F Goins; Justus B Cohen; Joseph C Glorioso
Equine herpesvirus 1 enters cells by two different pathways, and infection requires the activation of the cellular kinase ROCK1.
Journal of virology 2007;81(20):10879-89.
2007: Rahul Srinivasan; Shaohua Huang; Suchita Chaudhry; Adrian Sculptoreanu; David M Krisky; Michael Cascio; Peter A Friedman; william chesney de groat; Darren Wolfe; Joseph C Glorioso
An HSV vector system for selection of ligand-gated ion channel modulators.
Nature methods 2007;4(9):733-9.
2007: R Kato; Darren Wolfe; C H Coyle; Shaohua Huang; James B Wechuck; William F Goins; David M Krisky; T Tsukamoto; Joel B Nelson; Joseph C Glorioso; Michael B Chancellor; Naoki Yoshimura
Herpes simplex virus vector-mediated delivery of glial cell line-derived neurotrophic factor rescues erectile dysfunction following cavernous nerve injury.
Gene therapy 2007;14(18):1344-52.
2007: Ajay Niranjan; Wendy Fellows; William Stauffer; Edward A Burton; Chang-Sook Hong; L Dade Lunsford; Douglas Kondziolka; Joseph C Glorioso; Glenn T Gobbel
Survival of transplanted neural progenitor cells enhanced by brain irradiation.
Journal of neurosurgery 2007;107(2):383-91.
2007: Munmun Chattopadhyay; Marina Mata; James Goss; Darren Wolfe; Shaohua Huang; Joseph C Glorioso; David J Fink
Prolonged preservation of nerve function in diabetic neuropathy in mice by herpes simplex virus-mediated gene transfer.
Diabetologia 2007;50(7):1550-8.
2007: Shuanglin Hao; Marina Mata; Joseph C Glorioso; David J Fink
Gene transfer to interfere with TNFalpha signaling in neuropathic pain.
Gene therapy 2007;14(13):1010-6.
2007: James R Goss; William F Goins; Joseph C Glorioso
Gene therapy applications for the treatment of neuropathic pain.
Expert review of neurotherapeutics 2007;7(5):487-506.
2007: Marianna Tsvitov; Arthur R Frampton; Waris A Shah; Steven K Wendell; Ali Ozuer; Zoher Kapacee; William F Goins; Justus B Cohen; Joseph C Glorioso
Characterization of soluble glycoprotein D-mediated herpes simplex virus type 1 infection.
Virology 2007;360(2):477-91.
2006: Veljko Puskovic; Darren Wolfe; James B Wechuck; David M Krisky; Jeff Collins; Joseph C Glorioso; David J Fink; Marina Mata
HSV-mediated delivery of erythropoietin restores dopaminergic function in MPTP-treated mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(5):710-5.
2006: Canping Jiang; Mohammad M Ataai; Ali Ozuer; David M Krisky; James B Wechuck; Soraya Pornsuwan; Fazard Pourarian; Joseph C Glorioso
Inactivation of herpes simplex type 1 gene vector on immobilized metal affinity chromatography: oxidative damage by hydroxyl free radicals and its prevention.
Biotechnology and bioengineering 2006;95(1):48-57.
2006: Canping Jiang; Joseph C Glorioso; Mohammad M Ataai
Presence of imidazole in loading buffer prevents formation of free radical in immobilized metal affinity chromatography and dramatically improves the recovery of herpes simplex virus type 1 gene therapy vectors.
Journal of chromatography. A 2006;1121(1):40-5.
2006: Chang-Sook Hong; William F Goins; James R Goss; Edward A Burton; Joseph C Glorioso
Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer's disease-related amyloid-beta peptide in vivo.
Gene therapy 2006;13(14):1068-79.
2006: Xiang-min Peng; Zhi-gang Zhou; Joseph C Glorioso; David J Fink; Marina Mata
Tumor necrosis factor-alpha contributes to below-level neuropathic pain after spinal cord injury.
Annals of neurology 2006;59(5):843-51.
2006: Shuanglin Hao; Marina Mata; Joseph C Glorioso; David J Fink
HSV-mediated expression of interleukin-4 in dorsal root ganglion neurons reduces neuropathic pain.
Molecular pain 2006;2():6.
2006: Heechung Kwon; Qing Bai; Hyun-Jung Baek; Kelly Felmet; Edward A Burton; William F Goins; Justus B Cohen; Joseph C Glorioso
Soluble V domain of Nectin-1/HveC enables entry of herpes simplex virus type 1 (HSV-1) into HSV-resistant cells by binding to viral glycoprotein D.
Journal of virology 2006;80(1):138-48.
2005: Munmun Chattopadhyay; David M Krisky; Darren Wolfe; Joseph C Glorioso; Marina Mata; David J Fink
HSV-mediated gene transfer of vascular endothelial growth factor to dorsal root ganglia prevents diabetic neuropathy.
Gene therapy 2005;12(18):1377-84.
2005: Edward A Burton; David J Fink; Joseph C Glorioso
Replication-defective genomic HSV gene therapy vectors: design, production and CNS applications.
Current opinion in molecular therapeutics 2005;7(4):326-36.
2005: Munmun Chattopadhyay; Darren Wolfe; Marina Mata; Shaohua Huang; Joseph C Glorioso; David J Fink
Long-term neuroprotection achieved with latency-associated promoter-driven herpes simplex virus gene transfer to the peripheral nervous system.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(2):307-13.
2005: Shuanglin Hao; Marina Mata; Darren Wolfe; Shaohua Huang; Joseph C Glorioso; David J Fink
Gene transfer of glutamic acid decarboxylase reduces neuropathic pain.
Annals of neurology 2005;57(6):914-8.
2005: Arthur R Frampton; William F Goins; K Nakano; Edward A Burton; Joseph C Glorioso
HSV trafficking and development of gene therapy vectors with applications in the nervous system.
Gene therapy 2005;12(11):891-901.
2005: Nelson E Bennett; Jang H Kim; Darren P Wolfe; Katsumi Sasaki; Naoki Yoshimura; William F Goins; Shaohua Huang; Joel B Nelson; william chesney de groat; Joseph C Glorioso; Michael B Chancellor
Improvement in erectile dysfunction after neurotrophic factor gene therapy in diabetic rats.
The Journal of urology 2005;173(5):1820-4.
2005: Kenji Nakano; Tomoki Todo; Gang Zhao; Koji Yamaguchi; Syoji Kuroki; Justus B Cohen; Joseph C Glorioso; Masao Tanaka
Enhanced efficacy of conditionally replicating herpes simplex virus (G207) combined with 5-fluorouracil and surgical resection in peritoneal cancer dissemination models.
The journal of gene medicine 2005;7(5):638-48.
2005: Shusuke Moriuchi; Joseph C Glorioso; Motohiko Maruno; Shuichi Izumoto; Darren Wolfe; Shaohua Huang; Justus B Cohen; Toshiki Yoshimine
Combination gene therapy for glioblastoma involving herpes simplex virus vector-mediated codelivery of mutant IkappaBalpha and HSV thymidine kinase.
Cancer gene therapy 2005;12(5):487-96.
2005: Kenji Nakano; Ryutaro Asano; Kouhei Tsumoto; Heechung Kwon; William F Goins; Izumi Kumagai; Justus B Cohen; Joseph C Glorioso
Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(4):617-26.
2005: Arthur R Frampton; William F Goins; Justus B Cohen; Jens von Einem; Nikolaus Osterrieder; Dennis J O'Callaghan; Joseph C Glorioso
Equine herpesvirus 1 utilizes a novel herpesvirus entry receptor.
Journal of virology 2005;79(5):3169-73.
2005: Radosveta P Koldamova; Iliya Lefterov; Matthias Staufenbiel; Darren Wolfe; Shaohua Huang; Joseph C Glorioso; Michael Walter; Michael Roth; John Lazo
The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease.
The Journal of biological chemistry 2005;280(6):4079-88.
2005: J Fradette; Darren Wolfe; William F Goins; Shaohua Huang; R M Flanigan; Joseph C Glorioso
HSV vector-mediated transduction and GDNF secretion from adipose cells.
Gene therapy 2005;12(1):48-58.
2004: Darren Wolfe; A Niranjan; Anita M Trichel; Clayton A Wiley; Ali Ozuer; Emanuel Kanal; D Kondziolka; David M Krisky; James Goss; Neal A DeLuca; Michael Murphey-Corb; Joseph C Glorioso
Safety and biodistribution studies of an HSV multigene vector following intracranial delivery to non-human primates.
Gene therapy 2004;11(23):1675-84.
2004: Katsumi Sasaki; Michael B Chancellor; William F Goins; Michael W Phelan; Joseph C Glorioso; william chesney de groat; Naoki Yoshimura
Gene therapy using replication-defective herpes simplex virus vectors expressing nerve growth factor in a rat model of diabetic cystopathy.
Diabetes 2004;53(10):2723-30.
2004: Canping Jiang; James B Wechuck; William F Goins; David M Krisky; Darren Wolfe; Mohammad M Ataai; Joseph C Glorioso
Immobilized cobalt affinity chromatography provides a novel, efficient method for herpes simplex virus type 1 gene vector purification.
Journal of virology 2004;78(17):8994-9006.
2004: Veljko Puskovic; Darren Wolfe; James Goss; Shaohua Huang; Marina Mata; Joseph C Glorioso; David J Fink
Prolonged biologically active transgene expression driven by HSV LAP2 in brain in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(1):67-75.
2004: Jun Liu; Darren Wolfe; Shuanglin Hao; Shaohua Huang; Joseph C Glorioso; Marina Mata; David J Fink
Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(1):57-66.
2004: Edward Trybala; Sven-Olof Olofsson; Kristina Mårdberg; Bo Svennerholm; Kimiko Umemoto; Joseph C Glorioso; Tomas Bergström
Structural and functional features of the polycationic peptide required for inhibition of herpes simplex virus invasion of cells.
Antiviral research 2004;62(3):125-34.
2004: Munmun Chattopadhyay; James Goss; Darren Wolfe; William C Goins; Shaohua Huang; Joseph C Glorioso; Marina Mata; David J Fink
Protective effect of herpes simplex virus-mediated neurotrophin gene transfer in cisplatin neuropathy.
Brain : a journal of neurology 2004;127(Pt 4):929-39.
2004: Joseph C Glorioso; David J Fink
Herpes vector-mediated gene transfer in treatment of diseases of the nervous system.
Annual review of microbiology 2004;58():253-71.
2004: Darren Wolfe; James B Wechuck; David M Krisky; Julie P Goff; William F Goins; Ali Ozuer; Michael E Epperly; Joel S Greenberger; David J Fink; Joseph C Glorioso
Delivery of herpes simplex virus-based vectors to stem cells.
Methods in molecular biology (Clifton, N.J.) 2004;246():339-52.
2004: Ajay Niranjan; Darren Wolfe; Wendy Fellows; William F Goins; Joseph C Glorioso; Douglas Kondziolka; L Dade Lunsford
Gene transfer to glial tumors using herpes simplex virus.
Methods in molecular biology (Clifton, N.J.) 2004;246():323-37.
2004: James R Goss; Atsushi Natsume; Darren Wolfe; Marina Mata; Joseph C Glorioso; David J Fink
Delivery of herpes simplex virus-based vectors to the nervous system.
Methods in molecular biology (Clifton, N.J.) 2004;246():309-22.
2004: William F Goins; Darren Wolfe; David M Krisky; Qing Bai; Edward A Burton; David J Fink; Joseph C Glorioso
Delivery using herpes simplex virus: an overview.
Methods in molecular biology (Clifton, N.J.) 2004;246():257-99.
2004: Marina Mata; Joseph C Glorioso; David J Fink
Gene therapy: novel treatments for polyneuropathy and chronic pain.
Current neurology and neuroscience reports 2004;4(1):1-2.
2003: Atsushi Natsume; Darren Wolfe; Jian Hu; Shaohua Huang; Veljko Puskovic; Joseph C Glorioso; David J Fink; Marina Mata
Enhanced functional recovery after proximal nerve root injury by vector-mediated gene transfer.
Experimental neurology 2003;184(2):878-86.
2003: Marina Mata; Joseph C Glorioso; David J Fink
Gene transfer to the nervous system: prospects for novel treatments directed at diseases of the aging nervous system.
The journals of gerontology. Series A, Biological sciences and medical sciences 2003;58(12):M1111-8.
2003: Joseph C Glorioso; Marina Mata; David J Fink
Exploiting the neurotherapeutic potential of peptides: targeted delivery using HSV vectors.
Expert opinion on biological therapy 2003;3(8):1233-9.
2003: Marina Mata; Joseph C Glorioso; David J Fink
Development of HSV-mediated gene transfer for the treatment of chronic pain.
Experimental neurology 2003;184 Suppl 1():S25-9.
2003: David J Fink; Joseph C Glorioso; Marina Mata
Therapeutic gene transfer with herpes-based vectors: studies in Parkinson's disease and motor nerve regeneration.
Experimental neurology 2003;184 Suppl 1():S19-24.
2003: Joseph C Glorioso; Marina Mata; David J Fink
Gene therapy for chronic pain.
Current opinion in molecular therapeutics 2003;5(5):483-8.
2003: Ajay Niranjan; Darren Wolfe; Masakazu Tamura; M Karina Soares; David M Krisky; L Dade Lunsford; Songhui Li; Wendy Fellows-Mayle; Neal A DeLuca; Justus B Cohen; Joseph C Glorioso
Treatment of rat gliosarcoma brain tumors by HSV-based multigene therapy combined with radiosurgery.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(4):530-42.
2003: Shuanglin Hao; Marina Mata; Darren Wolfe; Shaohua Huang; Joseph C Glorioso; David J Fink
HSV-mediated gene transfer of the glial cell-derived neurotrophic factor provides an antiallodynic effect on neuropathic pain.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):367-75.
2003: Edward A Burton; Joseph C Glorioso; David J Fink
Gene therapy progress and prospects: Parkinson's disease.
Gene therapy 2003;10(20):1721-7.
2003: David J Fink; Marina Mata; Joseph C Glorioso
Cell and gene therapy in the treatment of pain.
Advanced drug delivery reviews 2003;55(8):1055-64.
2003: Donald B Kohn; Michel Sadelain; Cynthia Dunbar; David M Bodine; Hans-Peter Kiem; Fabio Candotti; John F Tisdale; Isabelle Riviére; C Anthony Blau; Robert E Richard; Brian P Sorrentino; Jan A Nolta; Harry L Malech; Malcolm Brenner; Kenneth Cornetta; Joy Cavagnaro; Katherine High; Joseph C Glorioso
American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(2):180-7.
2003: Motohiro Misumi; Toshiya Suzuki; Shusuke Moriuchi; Joseph C Glorioso; Masami Bessho
In vitro thymidine kinase/ganciclovir-based suicide gene therapy using replication defective herpes simplex virus-1 against leukemic B-cell malignancies (MCL, HCL, B-CLL).
Leukemia research 2003;27(8):695-9.
2003: Donald B Kohn; Michel Sadelain; Joseph C Glorioso
Occurrence of leukaemia following gene therapy of X-linked SCID.
Nature reviews. Cancer 2003;3(7):477-88.
2003: Q Yao; S Wang; Andrea Gambotto; Joseph C Glorioso; Christopher H Evans; Paul D Robbins; Steven C Ghivizzani; Thomas J Oligino
Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium.
Gene therapy 2003;10(12):1055-60.
2003: Joseph C Glorioso; Marina Mata; David J Fink
Therapeutic gene transfer to the nervous system using viral vectors.
Journal of neurovirology 2003;9(2):165-72.
2003: Shuanglin Hao; Marina Mata; William F Goins; Joseph C Glorioso; David J Fink
Transgene-mediated enkephalin release enhances the effect of morphine and evades tolerance to produce a sustained antiallodynic effect in neuropathic pain.
Pain 2003;102(1-2):135-42.
2003: Edward A Burton; Chang-Sook Hong; Joseph C Glorioso
The stable 2.0-kilobase intron of the herpes simplex virus type 1 latency-associated transcript does not function as an antisense repressor of ICP0 in nonneuronal cells.
Journal of virology 2003;77(6):3516-30.
2003: Munmun Chattopadhyay; James Goss; David Lacomis; William C Goins; Joseph C Glorioso; Marina Mata; David J Fink
Protective effect of HSV-mediated gene transfer of nerve growth factor in pyridoxine neuropathy demonstrates functional activity of trkA receptors in large sensory neurons of adult animals.
The European journal of neuroscience 2003;17(4):732-40.
2003: Hong Liang Guo; Darren Wolfe; Michael W Epperly; Shaohua Huang; Kaihong Liu; Joseph C Glorioso; Joel S Greenberger; David Blumberg
Gene transfer of human manganese superoxide dismutase protects small intestinal villi from radiation injury.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(2):229-35; discussion 235-6.
2003: Zhibao Mi; Steven C Ghivizzani; Eric R Lechman; Joseph C Glorioso; Christopher H Evans; Paul D Robbins
Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees.
Arthritis research & therapy 2003;5(3):R132-9.
2003: Edward A Burton; Shaohua Huang; William F Goins; Joseph C Glorioso
Use of the herpes simplex viral genome to construct gene therapy vectors.
Methods in molecular medicine 2003;76():1-31.
2002: Edward A Burton; David J Fink; Joseph C Glorioso
Gene delivery using herpes simplex virus vectors.
DNA and cell biology 2002;21(12):915-36.
2002: Marina Mata; Joseph C Glorioso; David J Fink
Targeted gene delivery to the nervous system using herpes simplex virus vectors.
Physiology & behavior 2002;77(4-5):483-8.
2002: F Miura; Shusuke Moriuchi; M Maeda; A Sano; Motohiko Maruno; A M Tsanaclis; R Marino; Joseph C Glorioso; Toshiki Yoshimine
Sustained release of low-dose ganciclovir from a silicone formulation prolonged the survival of rats with gliosarcomas under herpes simplex virus thymidine kinase suicide gene therapy.
Gene therapy 2002;9(24):1653-8.
2002: James R Goss; Cara F Harley; Marina Mata; Mark E O'Malley; William F Goins; XiaoPing Hu; Joseph C Glorioso; David J Fink
Herpes vector-mediated expression of proenkephalin reduces bone cancer pain.
Annals of neurology 2002;52(5):662-5.
2002: Edward A Burton; Qing Bai; William F Goins; Joseph C Glorioso
Replication-defective genomic herpes simplex vectors: design and production.
Current opinion in biotechnology 2002;13(5):424-8.
2002: William F Goins; Pierfrancesco Marconi; David M Krisky; Darren Wolfe; Joseph C Glorioso; Ramesh Ramakrishnan; David J Fink
Construction of replication-defective herpes simplex virus vectors.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2002;Chapter 12():Unit 12.11.
2002: James B Wechuck; Ali Ozuer; William F Goins; Darren Wolfe; Thomas J Oligino; Joseph C Glorioso; Mohammad M Ataai
Effect of temperature, medium composition, and cell passage on production of herpes-based viral vectors.
Biotechnology and bioengineering 2002;79(1):112-9.
2002: James R Goss; William F Goins; David Lacomis; Marina Mata; Joseph C Glorioso; David J Fink
Herpes simplex-mediated gene transfer of nerve growth factor protects against peripheral neuropathy in streptozotocin-induced diabetes in the mouse.
Diabetes 2002;51(7):2227-32.
2002: Xiao-Ping Chen; Marina Mata; Mary Kelley; Joseph C Glorioso; David J Fink
The relationship of herpes simplex virus latency associated transcript expression to genome copy number: a quantitative study using laser capture microdissection.
Journal of neurovirology 2002;8(3):204-10.
2002: Ali Ozuer; James B Wechuck; Brian A Russell; Darren Wolfe; William F Goins; Joseph C Glorioso; Mohammad M Ataai
Evaluation of infection parameters in the production of replication-defective HSV-1 viral vectors.
Biotechnology progress 2002;18(3):476-82.
2002: Shusuke Moriuchi; Darren Wolfe; Masakazu Tamura; Toshiki Yoshimine; F Miura; Justus B Cohen; Joseph C Glorioso
Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model.
Gene therapy 2002;9(9):584-91.
2002: Ali Ozuer; James B Wechuck; William F Goins; Darren Wolfe; Joseph C Glorioso; Mohammad M Ataai
Effect of genetic background and culture conditions on the production of herpesvirus-based gene therapy vectors.
Biotechnology and bioengineering 2002;77(6):685-92.
2002: Masaki Iwai; Yoshinori Harada; Michiaki Ishii; Kei Kashima; Osam Mazda; Masakazu Tamura; Darren Wolfe; William F Goin; Joseph C Glorioso
Suicide gene therapy of human hepatoma and its peritonitis carcinomatosis by a vector of replicative-deficient herpes simplex virus.
Biochemical and biophysical research communications 2002;291(4):855-60.
2002: Joseph C Glorioso; David J Fink
Use of HSV vectors to modify the nervous system.
Current opinion in drug discovery & development 2002;5(2):289-95.
2002: William F Goins; David M Krisky; Darren P Wolfe; David J Fink; Joseph C Glorioso
Development of replication-defective herpes simplex virus vectors.
Methods in molecular medicine 2002;69():481-507.
2002: Atsushi Natsume; Marina Mata; Darren Wolfe; Thomas J Oligino; James Goss; Shaohua Huang; Joseph C Glorioso; David J Fink
Bcl-2 and GDNF delivered by HSV-mediated gene transfer after spinal root avulsion provide a synergistic effect.
Journal of neurotrauma 2002;19(1):61-8.
2002: Munmun Chattopadhyay; Darren Wolfe; Shaohua Huang; James Goss; Joseph C Glorioso; Marina Mata; David J Fink
In vivo gene therapy for pyridoxine-induced neuropathy by herpes simplex virus-mediated gene transfer of neurotrophin-3.
Annals of neurology 2002;51(1):19-27.
2001: Edward A Burton; Qing Bai; William F Goins; Joseph C Glorioso
Targeting gene expression using HSV vectors.
Advanced drug delivery reviews 2001;53(2):155-70.
2001: Ruffini Francesca; Roberto Furlan; PL Poliani; Elena Brambilla; Pierfrancesco Marconi; Alessandra Bergami; G Desina; Joseph C Glorioso; Giancarlo Comi; Gianvito Martino
Fibroblast growth factor-II gene therapy reverts the clinical course and the pathological signs of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice.
Gene therapy 2001;8(16):1207-13.
2001: Kristina Mårdberg; Edward Trybala; Joseph C Glorioso; Tomas Bergström
Mutational analysis of the major heparan sulfate-binding domain of herpes simplex virus type 1 glycoprotein C.
The Journal of general virology 2001;82(Pt 8):1941-50.
2001: Q Yao; Shaomeng Wang; Joseph C Glorioso; Christopher H Evans; Paul D Robbins; Steven C Ghivizzani; Thomas J Oligino
Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(6):901-10.
2001: Naoki Yoshimura; Michael E Franks; Katsumi Sasaki; William F Goins; James Goss; Teruhiko Yokoyama; Matthew Fraser; Satoshi Seki; J Fink; Joseph C Glorioso; william chesney de groat; Michael B Chancellor
Gene therapy of bladder pain with herpes simplex virus (HSV) vectors expressing preproenkephalin (PPE).
Urology 2001;57(6 Suppl 1):116.
2001: Atsushi Natsume; Marina Mata; James Goss; Shaohua Huang; Darren Wolfe; Thomas J Oligino; Joseph C Glorioso; David J Fink
Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration.
Experimental neurology 2001;169(2):231-8.
2001: PL Poliani; Herbert P M Brok; Roberto Furlan; Ruffini Francesca; Alessandra Bergami; G Desina; Pierfrancesco Marconi; Marco Rovaris; Antonio Uccelli; Joseph C Glorioso; Giuseppe Penna; Luciano Adorini; Giancarlo Comi; B 't Hart; Gianvito Martino
Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis.
Human gene therapy 2001;12(8):905-20.
2001: William F Goins; Naoki Yoshimura; Michael W Phelan; Teruhiko Yokoyama; Matthew Fraser; H Ozawa; J R Bennett N; william chesney de groat; Joseph C Glorioso; Michael B Chancellor
Herpes simplex virus mediated nerve growth factor expression in bladder and afferent neurons: potential treatment for diabetic bladder dysfunction.
The Journal of urology 2001;165(5):1748-54.
2001: James R Goss; Marina Mata; William F Goins; H H Wu; Joseph C Glorioso; David J Fink
Antinociceptive effect of a genomic herpes simplex virus-based vector expressing human proenkephalin in rat dorsal root ganglion.
Gene therapy 2001;8(7):551-6.
2001: M Yamada; Atsushi Natsume; Marina Mata; Thomas J Oligino; James Goss; Joseph C Glorioso; David J Fink
Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion.
Experimental neurology 2001;168(2):225-30.
2001: Edward A Burton; James B Wechuck; Steven K Wendell; William F Goins; David J Fink; Joseph C Glorioso
Multiple applications for replication-defective herpes simplex virus vectors.
Stem cells (Dayton, Ohio) 2001;19(5):358-77.
2001: Roberto Furlan; PL Poliani; Pierfrancesco Marconi; Alessandra Bergami; Ruffini Francesca; Luciano Adorini; Joseph C Glorioso; Giancarlo Comi; Gianvito Martino
Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice.
Gene therapy 2001;8(1):13-9.
2001: Darren Wolfe; William F Goins; T J Kaplan; Saverio Capuano; J Fradette; M Murphey-Corb; Paul D Robbins; Justus B Cohen; Joseph C Glorioso
Herpesvirus-mediated systemic delivery of nerve growth factor.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(1):61-9.
2000: Waleed O Arafat; Enrique Casado; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel; Jesús Gómez-Navarro
Genetically modified CD34+ cells exert a cytotoxic bystander effect on human endothelial and cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4442-8.
2000: Zhibao Mi; Steven C Ghivizzani; Eric R Lechman; D Jaffurs; Joseph C Glorioso; Christopher H Evans; Paul D Robbins
Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints.
Arthritis and rheumatism 2000;43(11):2563-70.
2000: X p Chen; Juan Li; Marina Mata; James Goss; Darren Wolfe; Joseph C Glorioso; David J Fink
Herpes simplex virus type 1 ICP0 protein does not accumulate in the nucleus of primary neurons in culture.
Journal of virology 2000;74(21):10132-41.
2000: RJ Rouse; W Seifried; S K Mistry; William F Goins; Joseph C Glorioso
Herpes simplex virus-enhanced cationic lipid/DNA-mediated transfection.
BioTechniques 2000;29(4):810-4.
2000: Shusuke Moriuchi; David M Krisky; Pierfrancesco Marconi; Masakazu Tamura; K Shimizu; Toshiki Yoshimine; Justus B Cohen; Joseph C Glorioso
HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma.
Gene therapy 2000;7(17):1483-90.
2000: Ajay Niranjan; Shusuke Moriuchi; L Dade Lunsford; Douglas Kondziolka; John C Flickinger; Wendy Fellows; Swaminathan Rajendiran; Masakazu Tamura; Justus B Cohen; Joseph C Glorioso
Effective treatment of experimental glioblastoma by HSV vector-mediated TNF alpha and HSV-tk gene transfer in combination with radiosurgery and ganciclovir administration.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(2):114-20.
2000: Joseph C Glorioso; Leaf Huang; C Dunbar; P L Felgner
Highlights from the third annual ASGT meeting. American Society of Gene Therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(2):96-100.
2000: Gianvito Martino; PL Poliani; Roberto Furlan; Pierfrancesco Marconi; Joseph C Glorioso; Luciano Adorini; G Comi
Cytokine therapy in immune-mediated demyelinating diseases of the central nervous system: a novel gene therapy approach.
Journal of neuroimmunology 2000;107(2):184-90.
2000: Q Yao; Joseph C Glorioso; C H Evans; Paul D Robbins; Imre Kovesdi; Thomas J Oligino; Steven C Ghivizzani
Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining.
The journal of gene medicine 2000;2(3):210-9.
2000: James B Wechuck; William F Goins; Joseph C Glorioso; Mohammad M Ataai
Effect of protease inhibitors on yield of HSV-1-based viral vectors.
Biotechnology progress 2000;16(3):493-6.
2000: Dina Anderson; S Laquerre; K Ghosh; H P Ghosh; William F Goins; Justus B Cohen; Joseph C Glorioso
Pseudotyping of glycoprotein D-deficient herpes simplex virus type 1 with vesicular stomatitis virus glycoprotein G enables mutant virus attachment and entry.
Journal of virology 2000;74(5):2481-7.
2000: Joseph C Glorioso
Perspectives on viral vector design and applications.
Advances in virus research 2000;55():403-7.
2000: Pierfrancesco Marconi; Masakazu Tamura; Shusuke Moriuchi; David M Krisky; Ajay Niranjan; William F Goins; Justus B Cohen; Joseph C Glorioso
Connexin 43-enhanced suicide gene therapy using herpesviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(1):71-81.
2000: Jesús Gómez-Navarro; Juan L Contreras; Waleed O Arafat; Xiao Ling Jiang; David M Krisky; Thomas J Oligino; Pierfrancesco Marconi; B Hubbard; Joseph C Glorioso; David T Curiel; Judith M Thomas
Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model.
Gene therapy 2000;7(1):43-52.
2000: David J Fink; Neal A DeLuca; M Yamada; Darren P Wolfe; Joseph C Glorioso
Design and application of HSV vectors for neuroprotection.
Gene therapy 2000;7(2):115-9.
1999: Thomas J Oligino; Steven C Ghivizzani; Darren Wolfe; Eric R Lechman; David M Krisky; Zhibao Mi; C Evans; Paul Robbins; Joseph C Glorioso
Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis.
Gene therapy 1999;6(10):1713-20.
1999: Darren Wolfe; William F Goins; M Yamada; Shusuke Moriuchi; David M Krisky; Thomas J Oligino; Pierfrancesco Marconi; David J Fink; Joseph C Glorioso
Engineering herpes simplex virus vectors for CNS applications.
Experimental neurology 1999;159(1):34-46.
1999: Pierfrancesco Marconi; Michele Simonato; Silvia Zucchini; Gianni Bregola; Rafaela Argnani; David M Krisky; Joseph C Glorioso; Roberto Manservigi
Replication-defective herpes simplex virus vectors for neurotrophic factor gene transfer in vitro and in vivo.
Gene therapy 1999;6(5):904-12.
1999: M R Alvira; William F Goins; Justus B Cohen; Joseph C Glorioso
Genetic studies exposing the splicing events involved in herpes simplex virus type 1 latency-associated transcript production during lytic and latent infection.
Journal of virology 1999;73(5):3866-76.
1999: M Yamada; Thomas J Oligino; Marina Mata; James R Goss; Joseph C Glorioso; David J Fink
Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):4078-83.
1999: J D Whalen; E L Lechman; Casey A Carlos; K Weiss; Imre Kovesdi; Joseph C Glorioso; Paul D Robbins; Christopher H Evans
Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3625-32.
1999: William F Goins; K A Lee; James Cavalcoli; Mark E O'Malley; Steven T DeKosky; David J Fink; Joseph C Glorioso
Herpes simplex virus type 1 vector-mediated expression of nerve growth factor protects dorsal root ganglion neurons from peroxide toxicity.
Journal of virology 1999;73(1):519-32.
1998: Shusuke Moriuchi; Thomas J Oligino; David M Krisky; Pierfrancesco Marconi; David J Fink; J Cohen; Joseph C Glorioso
Enhanced tumor cell killing in the presence of ganciclovir by herpes simplex virus type 1 vector-directed coexpression of human tumor necrosis factor-alpha and herpes simplex virus thymidine kinase.
Cancer research 1998;58(24):5731-7.
1998: David M Krisky; Darren Wolfe; William F Goins; Pierfrancesco Marconi; R Ramakrishnan; Marina Mata; RJ Rouse; David J Fink; Joseph C Glorioso
Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons.
Gene therapy 1998;5(12):1593-603.
1998: S Laquerre; Dina Anderson; Donna B Stolz; Joseph C Glorioso
Recombinant herpes simplex virus type 1 engineered for targeted binding to erythropoietin receptor-bearing cells.
Journal of virology 1998;72(12):9683-97.
1998: T Suzuki; A Piche; K Kasono; Jialing Xiang; Jesus Gomez-Navarro; Shusuke Moriuchi; David M Krisky; Thomas J Oligino; Joseph C Glorioso; Tyler J Curiel; David T Curiel
Efficient gene delivery into epstein-barr virus (EBV)-transformed human B cells mediated by replication-defective herpes simplex virus-1 (HSV-1): A gene therapy model for EBV-related B cell malignancy.
Biochemical and biophysical research communications 1998;252(3):686-90.
1998: David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; RJ Rouse; David J Fink; Justus B Cohen; simon simon watkins; Joseph C Glorioso
Development of herpes simplex virus replication-defective multigene vectors for combination gene therapy applications.
Gene therapy 1998;5(11):1517-30.
1998: Minghui Wang; Claudine Rancourt; Jesus Gomez-Navarro; David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel
High-efficacy thymidine kinase gene transfer to ovarian cancer cell lines mediated by herpes simplex virus type 1 vector.
Gynecologic oncology 1998;71(2):278-87.
1998: S Laquerre; Rafaela Argnani; Dina Anderson; Silvia Zucchini; Roberto Manservigi; Joseph C Glorioso
Heparan sulfate proteoglycan binding by herpes simplex virus type 1 glycoproteins B and C, which differ in their contributions to virus attachment, penetration, and cell-to-cell spread.
Journal of virology 1998;72(7):6119-30.
1998: S Laquerre; Dina Anderson; Rafaela Argnani; Joseph C Glorioso
Herpes simplex virus type 1 glycoprotein B requires a cysteine residue at position 633 for folding, processing, and incorporation into mature infectious virus particles.
Journal of virology 1998;72(6):4940-9.
1998: Thomas J Oligino; PL Poliani; Y Wang; S Y Tsai; Bert W O'Malley; David J Fink; Joseph C Glorioso
Drug inducible transgene expression in brain using a herpes simplex virus vector.
Gene therapy 1998;5(4):491-6.
1998: Nelly Kuklin; M Daheshia; Pierfrancesco Marconi; David M Krisky; RJ Rouse; Joseph C Glorioso; E Manican; Barry T Rouse
Modulation of mucosal and systemic immunity by enteric administration of nonreplicating herpes simplex virus expressing cytokines.
Virology 1998;240(2):245-53.
1997: David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; RJ Rouse; David J Fink; Joseph C Glorioso
Rapid method for construction of recombinant HSV gene transfer vectors.
Gene therapy 1997;4(10):1120-5.
1997: S Rasty; PL Poliani; David J Fink; Joseph C Glorioso
Deletion of the S component inverted repeat sequence c' and the nonessential genes U(S)1 through U(S)5 from the herpes simplex virus type 1 genome substantially impairs productive viral infection in cell culture and pathogenesis in the rat central nervous system.
Journal of neurovirology 1997;3(4):247-64.
1997: William F Goins; David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; R Ramakrishnan; PL Poliani; David J Fink; Joseph C Glorioso
Herpes simplex virus vectors for gene transfer to the nervous system.
Journal of neurovirology 1997;3 Suppl 1():S80-8.
1997: David J Fink; PL Poliani; Thomas J Oligino; David M Krisky; William F Goins; Joseph C Glorioso
Development of an HSV-based vector for the treatment of Parkinson's disease.
Experimental neurology 1997;144(1):103-21.
1997: David J Fink; Joseph C Glorioso
Engineering herpes simplex virus vectors for gene transfer to neurons.
Nature medicine 1997;3(3):357-9.
1997: Johnny Huard; G Akkaraju; simon simon watkins; M Pike-Cavalcoli; Joseph C Glorioso
LacZ gene transfer to skeletal muscle using a replication-defective herpes simplex virus type 1 mutant vector.
Human gene therapy 1997;8(4):439-52.
1997: William G. Feero; J David Rosenblatt; Johnny Huard; simon simon watkins; Michael W Epperly; Paula R Clemens; Stefan Kochanek; Joseph C Glorioso; Terence A Partridge; Eric Hoffman
Viral gene delivery to skeletal muscle: insights on maturation-dependent loss of fiber infectivity for adenovirus and herpes simplex type 1 viral vectors.
Human gene therapy 1997;8(4):371-80.
1997: Joseph C Glorioso; William F Goins; Martin C Schmidt; Thomas J Oligino; David M Krisky; Pierfrancesco Marconi; James Cavalcoli; R Ramakrishnan; PL Poliani; David J Fink
Engineering herpes simplex virus vectors for human gene therapy.
Advances in pharmacology (San Diego, Calif.) 1997;40():103-36.
1996: Johnny Huard; William G. Feero; simon simon watkins; Eric Hoffman; D J Rosenblatt; Joseph C Glorioso
The basal lamina is a physical barrier to herpes simplex virus-mediated gene delivery to mature muscle fibers.
Journal of virology 1996;70(11):8117-23.
1996: Pierfrancesco Marconi; David M Krisky; Thomas J Oligino; PL Poliani; R Ramakrishnan; William F Goins; David J Fink; Joseph C Glorioso
Replication-defective herpes simplex virus vectors for gene transfer in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11319-20.
1996: Thomas J Oligino; PL Poliani; Pierfrancesco Marconi; M A Bender; Martin C Schmidt; David J Fink; Joseph C Glorioso
In vivo transgene activation from an HSV-based gene therapy vector by GAL4:vp16.
Gene therapy 1996;3(10):892-9.
1996: S W French; Martin C Schmidt; Joseph C Glorioso
Involvement of a high-mobility-group protein in the transcriptional activity of herpes simplex virus latency-active promoter 2.
Molecular and cellular biology 1996;16(10):5393-9.
1996: R Ramakrishnan; PL Poliani; Myron M Levine; Joseph C Glorioso; David J Fink
Detection of herpes simplex virus type 1 latency-associated transcript expression in trigeminal ganglia by in situ reverse transcriptase PCR.
Journal of virology 1996;70(9):6519-23.
1996: K Soares; D Y Hwang; R Ramakrishnan; Martin C Schmidt; David J Fink; Joseph C Glorioso
cis-acting elements involved in transcriptional regulation of the herpes simplex virus type 1 latency-associated promoter 1 (LAP1) in vitro and in vivo.
Journal of virology 1996;70(8):5384-94.
1996: Christopher H Evans; Paul D Robbins; Steven C Ghivizzani; James H Herndon; Richard Kang; Alfred B Bahnson; John A Barranger; E M Elders; S Gay; Matthew M Tomaino; Mary Chester Wasko; simon simon watkins; Theresa L Whiteside; Joseph C Glorioso; Michael T Lotze; T M Wright
Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis.
Human gene therapy 1996;7(10):1261-80.
1996: S Rasty; P Thatikunta; J Gordon; Kamel Khalili; Shohreh Amini; Joseph C Glorioso
Human immunodeficiency virus tat gene transfer to the murine central nervous system using a replication-defective herpes simplex virus vector stimulates transforming growth factor beta 1 gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(12):6073-8.
1996: S Laquerre; Stanley Person; Joseph C Glorioso
Glycoprotein B of herpes simplex virus type 1 oligomerizes through the intermolecular interaction of a 28-amino-acid domain.
Journal of virology 1996;70(3):1640-50.
1996: David J Fink; Neal A DeLuca; William F Goins; Joseph C Glorioso
Gene transfer to neurons using herpes simplex virus-based vectors.
Annual review of neuroscience 1996;19():265-87.
1995: X Chen; Martin C Schmidt; William F Goins; Joseph C Glorioso
Two herpes simplex virus type 1 latency-active promoters differ in their contributions to latency-associated transcript expression during lytic and latent infections.
Journal of virology 1995;69(12):7899-908.
1995: Joseph C Glorioso; M A Bender; William F Goins; David J Fink; Neal A DeLuca
HSV as a gene transfer vector for the nervous system.
Molecular biotechnology 1995;4(1):87-99.
1995: Johnny Huard; William F Goins; Joseph C Glorioso
Herpes simplex virus type 1 vector mediated gene transfer to muscle.
Gene therapy 1995;2(6):385-92.
1995: J C Mester; PAULA PITHA-ROWE; Joseph C Glorioso
Antiviral activity of herpes simplex virus vectors expressing murine alpha 1-interferon.
Gene therapy 1995;2(3):187-96.
1995: Joseph C Glorioso; M A Bender; David J Fink; Neal A DeLuca
Herpes simplex virus vectors.
Molecular and cell biology of human diseases series 1995;5():33-63.
1995: David J Fink; R Ramakrishnan; Pierfrancesco Marconi; William F Goins; Thomas C Holland; Joseph C Glorioso
Advances in the development of herpes simplex virus-based gene transfer vectors for the nervous system.
Clinical neuroscience (New York, N.Y.) 1995;3(5):284-91.
1995: Joseph C Glorioso; Neal A DeLuca; David J Fink
Development and application of herpes simplex virus vectors for human gene therapy.
Annual review of microbiology 1995;49():675-710.
1994: Prashant Desai; Fred Homa; Stanley Person; Joseph C Glorioso
A genetic selection method for the transfer of HSV-1 glycoprotein B mutations from plasmid to the viral genome: preliminary characterization of transdominance and entry kinetics of mutant viruses.
Virology 1994;204(1):312-22.
1994: William F Goins; L R Sternberg; K D Croen; P R Krause; R L Hendricks; David J Fink; Stephen E Straus; Myron M Levine; Joseph C Glorioso
A novel latency-active promoter is contained within the herpes simplex virus type 1 UL flanking repeats.
Journal of virology 1994;68(4):2239-52.
1994: R Ramakrishnan; David J Fink; G Jiang; Prashant Desai; Joseph C Glorioso; Myron M Levine
Competitive quantitative PCR analysis of herpes simplex virus type 1 DNA and latency-associated transcript RNA in latently infected cells of the rat brain.
Journal of virology 1994;68(3):1864-73.
1994: Joseph C Glorioso; William F Goins; Neal A DeLuca; David J Fink
Development of herpes simplex virus as a gene transfer vector for the nervous system.
Gene therapy 1994;1 Suppl 1():S39.
1994: Joseph C Glorioso; William F Goins; C A Meaney; David J Fink; Neal A DeLuca
Gene transfer to brain using herpes simplex virus vectors.
Annals of neurology 1994;35 Suppl():S28-34.
1994: Joseph C Glorioso; William F Goins; David J Fink; Neal A DeLuca
Herpes simplex virus vectors and gene transfer to brain.
Developments in biological standardization 1994;82():79-87.
1993: G Bandara; G M Mueller; J Galea-Lauri; M H Tindal; Helga I Georgescu; M K Suchanek; G L Hung; Joseph C Glorioso; Paul D Robbins; Christopher H Evans
Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10764-8.
1993: Prashant Desai; R Ramakrishnan; Z W Lin; B Osak; Joseph C Glorioso; Myron M Levine
The RR1 gene of herpes simplex virus type 1 is uniquely trans activated by ICP0 during infection.
Journal of virology 1993;67(10):6125-35.
1993: A M Oyan; K E Dolter; Nina Langeland; William F Goins; Joseph C Glorioso; Lars Haarr; C S Crumpacker
Resistance of herpes simplex virus type 2 to neomycin maps to the N-terminal portion of glycoprotein C.
Journal of virology 1993;67(5):2434-41.
1993: Philip J Gage; Myron M Levine; Joseph C Glorioso
Syncytium-inducing mutations localize to two discrete regions within the cytoplasmic domain of herpes simplex virus type 1 glycoprotein B.
Journal of virology 1993;67(4):2191-201.
1993: Prashant Desai; Neal A DeLuca; Joseph C Glorioso; Stanley Person
Mutations in herpes simplex virus type 1 genes encoding VP5 and VP23 abrogate capsid formation and cleavage of replicated DNA.
Journal of virology 1993;67(3):1357-64.
1992: Christopher H Evans; G Bandara; G Mueller; Paul Robbins; Joseph C Glorioso; Helga I Georgescu
Synovial cell transplants for gene transfer to joints.
Transplantation proceedings 1992;24(6):2966.
1992: Philip J Gage; B Sauer; Myron M Levine; Joseph C Glorioso
A cell-free recombination system for site-specific integration of multigenic shuttle plasmids into the herpes simplex virus type 1 genome.
Journal of virology 1992;66(9):5509-15.
1992: K E Dolter; William F Goins; Myron M Levine; Joseph C Glorioso
Genetic analysis of type-specific antigenic determinants of herpes simplex virus glycoprotein C.
Journal of virology 1992;66(8):4864-73.
1992: G Bandara; Paul D Robbins; Helga I Georgescu; G M Mueller; Joseph C Glorioso; Christopher H Evans
Gene transfer to synoviocytes: prospects for gene treatment of arthritis.
DNA and cell biology 1992;11(3):227-31.
1992: David J Fink; L R Sternberg; P C Weber; Marina Mata; William F Goins; Joseph C Glorioso
In vivo expression of beta-galactosidase in hippocampal neurons by HSV-mediated gene transfer.
Human gene therapy 1992;3(1):11-9.
1991: S L Highlander; William F Goins; Stanley Person; Thomas C Holland; Myron M Levine; Joseph C Glorioso
Oligomer formation of the gB glycoprotein of herpes simplex virus type 1.
Journal of virology 1991;65(8):4275-83.
1990: K A Kimmel; K E Dolter; G M Toth; Myron M Levine; Joseph C Glorioso
Serologic type conversion of a herpes simplex virus type 1 (HSV-1) to an HSV-2 epitope caused by a single amino acid substitution in glycoprotein C.
Journal of virology 1990;64(8):4033-6.
1990: Nina Langeland; A M Oyan; Howard S Marsden; A Cross; Joseph C Glorioso; L J Moore; Lars Haarr
Localization on the herpes simplex virus type 1 genome of a region encoding proteins involved in adsorption to the cellular receptor.
Journal of virology 1990;64(3):1271-7.
1990: G E Kikuchi; Joseph C Glorioso; R Nairn
Cross-linking studies show that herpes simplex virus type 1 glycoprotein C molecules are clustered in the membrane of infected cells.
The Journal of general virology 1990;71 ( Pt 2)():455-8.
1990: C T Wu; Myron M Levine; F Homa; S L Highlander; Joseph C Glorioso
Characterization of the antigenic structure of herpes simplex virus type 1 glycoprotein C through DNA sequence analysis of monoclonal antibody-resistant mutants.
Journal of virology 1990;64(2):856-63.
1990: P C Weber; Myron M Levine; Joseph C Glorioso
Recombinogenic properties of herpes simplex virus type 1 DNA sequences resident in simian virus 40 minichromosomes.
Journal of virology 1990;64(1):300-6.
1990: Myron M Levine; A Krikos; Joseph C Glorioso; Fred Homa
Regulation of expression of the glycoprotein genes of herpes simplex virus type 1 (HSV-1).
Advances in experimental medicine and biology 1990;278():151-64.
1989: T D Palella; Y Hidaka; L J Silverman; Myron M Levine; Joseph C Glorioso; W N Kelley
Expression of human HPRT mRNA in brains of mice infected with a recombinant herpes simplex virus-1 vector.
Gene 1989;80(1):137-44.
1989: Clarence Chrisp; J C Sunstrum; D R Averill; Myron M Levine; Joseph C Glorioso
Characterization of encephalitis in adult mice induced by intracerebral inoculation of herpes simplex virus type 1 (KOS) and comparison with mutants showing decreased virulence.
Laboratory investigation; a journal of technical methods and pathology 1989;60(6):822-30.
1989: S L Highlander; D J Dorney; Philip J Gage; Thomas C Holland; W Cai; Stanley Person; Myron M Levine; Joseph C Glorioso
Identification of mar mutations in herpes simplex virus type 1 glycoprotein B which alter antigenic structure and function in virus penetration.
Journal of virology 1989;63(2):730-8.
1989: Y Hidaka; W N Kelley; Myron M Levine; Joseph C Glorioso; L J Silverman; T D Palella
Expression of human hypoxanthine guanine phosphoribosyltransferase mRNA in brains of mice infected with a recombinant herpes simplex virus type 1.
Transactions of the Association of American Physicians 1989;102():91-100.
1988: V Huff; W Cai; Joseph C Glorioso; Myron M Levine
The carboxy-terminal 41 amino acids of herpes simplex virus type 1 glycoprotein B are not essential for production of infectious virus particles.
Journal of virology 1988;62(11):4403-6.
1988: P C Weber; Myron M Levine; Joseph C Glorioso
Simple assay for quantitation of Tn5 inversion events in Escherichia coli and use of the assay in determination of plasmid copy number.
Journal of bacteriology 1988;170(10):4972-5.
1988: J C Sunstrum; Clarence Chrisp; Myron M Levine; Joseph C Glorioso
Pathogenicity of glycoprotein C negative mutants of herpes simplex virus type 1 for the mouse central nervous system.
Virus research 1988;11(1):17-32.
1988: P C Weber; M D Challberg; N J Nelson; Myron M Levine; Joseph C Glorioso
Inversion events in the HSV-1 genome are directly mediated by the viral DNA replication machinery and lack sequence specificity.
Cell 1988;54(3):369-81.
1988: S L Highlander; W H Cai; Stanley Person; Myron M Levine; Joseph C Glorioso
Monoclonal antibodies define a domain on herpes simplex virus glycoprotein B involved in virus penetration.
Journal of virology 1988;62(6):1881-8.
1988: Fred Homa; Joseph C Glorioso; Myron M Levine
A specific 15-bp TATA box promoter element is required for expression of a herpes simplex virus type 1 late gene.
Genes & development 1988;2(1):40-53.
1987: S L Highlander; S L Sutherland; Philip J Gage; David C Johnson; Myron M Levine; Joseph C Glorioso
Neutralizing monoclonal antibodies specific for herpes simplex virus glycoprotein D inhibit virus penetration.
Journal of virology 1987;61(11):3356-64.
1987: G E Kikuchi; S A Baker; Sofia D Merajver; J E Coligan; Myron M Levine; Joseph C Glorioso; R Nairn
Purification and structural characterization of herpes simplex virus glycoprotein C.
Biochemistry 1987;26(2):424-31.
1987: G A Bishop; L McCurry; S A Schwartz; Joseph C Glorioso
Activation of human natural killer cells by herpes simplex virus type 1-infected cells.
Intervirology 1987;28(2):78-88.
1986: S D Marlin; S L Highlander; Thomas C Holland; Myron M Levine; Joseph C Glorioso
Antigenic variation (mar mutations) in herpes simplex virus glycoprotein B can induce temperature-dependent alterations in gB processing and virus production.
Journal of virology 1986;59(1):142-53.
1985: A L Goldin; R M Sandri-Goldin; Joseph C Glorioso; Myron M Levine
Stable induction of a 51K cellular protein in neuronal cells surviving herpes simplex virus type 1 infection.
Virology 1985;142(2):398-405.
1985: S D Marlin; Thomas C Holland; Myron M Levine; Joseph C Glorioso
Epitopes of herpes simplex virus type 1 glycoprotein gC are clustered in two distinct antigenic sites.
Journal of virology 1985;53(1):128-36.
1984: G E Kikuchi; J E Coligan; Thomas C Holland; Myron M Levine; Joseph C Glorioso; R Nairn
Biochemical characterization of peptides from herpes simplex virus glycoprotein gC: loss of CNBr fragments from the carboxy terminus of truncated, secreted gC molecules.
Journal of virology 1984;52(3):806-15.
1984: Thomas C Holland; Fred Homa; S D Marlin; Myron M Levine; Joseph C Glorioso
Herpes simplex virus type 1 glycoprotein C-negative mutants exhibit multiple phenotypes, including secretion of truncated glycoproteins.
Journal of virology 1984;52(2):566-74.
1984: R M Sandri-Goldin; A L Goldin; Joseph C Glorioso; Myron M Levine
Herpes simplex virus thymidine kinase gene is stably maintained and expressed in cells transformed by protoplast fusion.
Somatic cell and molecular genetics 1984;10(2):129-38.
1984: L E Holland; R M Sandri-Goldin; A L Goldin; Joseph C Glorioso; Myron M Levine
Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45.
Journal of virology 1984;49(3):947-59.
1983: R M Sandri-Goldin; A L Goldin; L E Holland; Joseph C Glorioso; Myron M Levine
Expression of herpes simplex virus beta and gamma genes integrated in mammalian cells and their induction by an alpha gene product.
Molecular and cellular biology 1983;3(11):2028-44.
1983: Thomas C Holland; R M Sandri-Goldin; L E Holland; S D Marlin; Myron M Levine; Joseph C Glorioso
Physical mapping of the mutation in an antigenic variant of herpes simplex virus type 1 by use of an immunoreactive plaque assay.
Journal of virology 1983;46(2):649-52.
1983: Joseph C Glorioso; M S Szczesiul; S D Marlin; Myron M Levine
Inhibition of glycosylation of herpes simplex virus glycoproteins: identification of antigenic and immunogenic partially glycosylated glycopeptides on the cell surface membrane.
Virology 1983;126(1):1-18.
1983: Thomas C Holland; S D Marlin; Myron M Levine; Joseph C Glorioso
Antigenic variants of herpes simplex virus selected with glycoprotein-specific monoclonal antibodies.
Journal of virology 1983;45(2):672-82.
1983: R M Sandri-Goldin; A L Goldin; Myron M Levine; Joseph C Glorioso
High-efficiency transfer of DNA into eukaryotic cells by protoplast fusion.
Methods in enzymology 1983;101():402-11.
1981: R M Sandri-Goldin; A L Goldin; Myron M Levine; Joseph C Glorioso
High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion.
Molecular and cellular biology 1981;1(8):743-52.
1981: A L Goldin; R M Sandri-Goldin; Myron M Levine; Joseph C Glorioso
Cloning of herpes simplex virus type 1 sequences representing the whole genome.
Journal of virology 1981;38(1):50-8.