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Margaret Gnegy

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Gina M Leinninger; Jill B Becker; Laura A Cappellucci; Lyndsay Christensen; Miro Faouzi; Margaret E Gnegy; Young-Hwan Jo; Darren M Opland; Emmanuel N Pothos; Christopher J Rhodes; Audrey F Seasholtz; Robert C Thompson; Martin G Myers Jr
Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance.
Myung N Kim; Emily Jutkiewicz; Minjia Zhang; Margaret E Gnegy
The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.
Bipasha Guptaroy; Rheaclare Fraser; Aalisha Desai; Minjia Zhang; Margaret E Gnegy
Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters.

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2011: Gina M Leinninger; Jill B Becker; Laura A Cappellucci; Lyndsay Christensen; Miro Faouzi; Margaret E Gnegy; Young-Hwan Jo; Darren M Opland; Emmanuel N Pothos; Christopher J Rhodes; Audrey F Seasholtz; Robert C Thompson; Martin G Myers Jr
Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance.
Cell metabolism 2011;14(3):313-23.
2011: Myung N Kim; Emily Jutkiewicz; Minjia Zhang; Margaret E Gnegy
The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.
Neuropharmacology 2011;60(7-8):1126-34.
2011: Bipasha Guptaroy; Rheaclare Fraser; Aalisha Desai; Minjia Zhang; Margaret E Gnegy
Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters.
Molecular pharmacology 2011;79(3):520-32.
2010: Heather A O'Malley; Yanghae Park; Lori L Isom; Margaret E Gnegy
PKCbeta co-localizes with the dopamine transporter in mesencephalic neurons.
Neuroscience letters 2010;480(1):40-3.
2010: Maura L Perry; Gina M Leinninger; Rong Chen; Kathryn D Luderman; Hongyan Yang; Margaret E Gnegy; Martin G Myers Jr; Robert T Kennedy
Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats.
Journal of neurochemistry 2010;114(3):666-74.
2009: Cheryse A Furman; Charles B Lo; Stephanie Stokes; Jose A Esteban; Margaret E Gnegy
Rab 11 regulates constitutive dopamine transporter trafficking and function in N2A neuroblastoma cells.
Neuroscience letters 2009;463(1):78-81.
2009: Benjamin H Singer; Emily Jutkiewicz; Cynthia L Fuller; Robin J Lichtenwalner; Helen Zhang; Alan J Velander; Xiangquan Li; Margaret E Gnegy; Charles F Burant; Jack M Parent
Conditional ablation and recovery of forebrain neurogenesis in the mouse.
The Journal of comparative neurology 2009;514(6):567-82.
2009: Cheryse A Furman; Rong Chen; Bipasha Guptaroy; Minjia Zhang; Ronald W Holz; Margaret E Gnegy
Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(10):3328-36.
2009: Rong Chen; Cheryse A Furman; Minjia Zhang; Myung N Kim; Robert W Gereau; Michael Leitges; Margaret E Gnegy
Protein kinase Cbeta is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice.
The Journal of pharmacology and experimental therapeutics 2009;328(3):912-20.
2009: Bipasha Guptaroy; Minjia Zhang; Erica Bowton; Francesca Binda; Lei Shi; HAREL WEINSTEIN; Aurelio Galli; Jonathan A Javitch; Richard Neubig; Margaret E Gnegy
A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.
Molecular pharmacology 2009;75(3):514-24.
2008: Francesca Binda; Concetta Dipace; Erica Bowton; Sabrina D Robertson; Brandon J Lute; Jacob U Fog; Minjia Zhang; Namita Sen; Roger J Colbran; Margaret E Gnegy; Ulrik Gether; Jonathan A Javitch; Kevin Erreger; Aurelio Galli
Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux.
Molecular pharmacology 2008;74(4):1101-8.
2008: Kelly E Bosse; Emily Jutkiewicz; Margaret E Gnegy; John R Traynor
The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum.
Neuropharmacology 2008;55(5):755-62.
2008: Emily Jutkiewicz; Danielle M Nicolazzo; Myung N Kim; Margaret E Gnegy
Nicotine and amphetamine acutely cross-potentiate their behavioral and neurochemical responses in female Holtzman rats.
Psychopharmacology 2008;200(1):93-103.
2007: Prasanna K Thwar; Bipasha Guptaroy; Minjia Zhang; Margaret E Gnegy; Mark A Burns; Jennifer J Linderman
Simple transporter trafficking model for amphetamine-induced dopamine efflux.
Synapse (New York, N.Y.) 2007;61(7):500-14.
2007: Rong Chen; Minjia Zhang; Soo Park; Margaret E Gnegy
C57BL/6J mice show greater amphetamine-induced locomotor activation and dopamine efflux in the striatum than 129S2/SvHsd mice.
Pharmacology, biochemistry, and behavior 2007;87(1):158-63.
2005: L'aurelle A Johnson; Cheryse A Furman; Minjia Zhang; Bipasha Guptaroy; Margaret E Gnegy
Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation.
Neuropharmacology 2005;49(6):750-8.
2005: L'Aurelle A Johnson; Bipasha Guptaroy; David Lund; Susanna Shamban; Margaret E Gnegy
Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta.
The Journal of biological chemistry 2005;280(12):10914-9.
2004: Lana Kantor; Minjia Zhang; Bipasha Guptaroy; Yang Hae Park; Margaret E Gnegy
Repeated amphetamine couples norepinephrine transporter and calcium channel activities in PC12 cells.
The Journal of pharmacology and experimental therapeutics 2004;311(3):1044-51.
2004: Margaret E Gnegy; Habibeh Khoshbouei; Kelly Berg; Jonathan A Javitch; William Clarke; Minjia Zhang; Aurelio Galli
Intracellular Ca2+ regulates amphetamine-induced dopamine efflux and currents mediated by the human dopamine transporter.
Molecular pharmacology 2004;66(1):137-43.
2004: Habibeh Khoshbouei; Namita Sen; Bipasha Guptaroy; L 'Aurelle Johnson; David Lund; Margaret E Gnegy; Aurelio Galli; Jonathan A Javitch
N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux.
PLoS biology 2004;2(3):E78.
2003: Yang Hae Park; Lana Kantor; Bipasha Guptaroy; Minjia Zhang; Kevin Wang; Margaret E Gnegy
Repeated amphetamine treatment induces neurite outgrowth and enhanced amphetamine-stimulated dopamine release in rat pheochromocytoma cells (PC12 cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism.
Journal of neurochemistry 2003;87(6):1546-57.
2003: Margaret E Gnegy
The effect of phosphorylation on amphetamine-mediated outward transport.
European journal of pharmacology 2003;479(1-3):83-91.
2003: Kim M McGinnis; Margaret E Gnegy; Nicole Falk; Rathna Nath; Kevin Wang
Cytochrome c translocation does not lead to caspase activation in maitotoxin-treated SH-SY5Y neuroblastoma cells.
Neurochemistry international 2003;42(6):517-23.
2002: Yang Hae Park; Lana Kantor; Kevin Wang; Margaret E Gnegy
Repeated, intermittent treatment with amphetamine induces neurite outgrowth in rat pheochromocytoma cells (PC12 cells).
Brain research 2002;951(1):43-52.
2002: Lana Kantor; Yang Hae Park; Kevin Wang; Margaret E Gnegy
Enhanced amphetamine-mediated dopamine release develops in PC12 cells after repeated amphetamine treatment.
European journal of pharmacology 2002;451(1):27-35.
2001: N Mukerjee; Kim M McGinnis; Margaret E Gnegy; Kevin Wang
Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.
Biochemical and biophysical research communications 2001;285(5):1192-9.
2001: Lana Kantor; GH Hewlett; Yang Hae Park; Sarah M Richardson-Burns; M J Mellon; Margaret E Gnegy
Protein kinase C and intracellular calcium are required for amphetamine-mediated dopamine release via the norepinephrine transporter in undifferentiated PC12 cells.
The Journal of pharmacology and experimental therapeutics 2001;297(3):1016-24.
2001: Kim M McGinnis; Kevin Wang; Margaret E Gnegy
Calcium/calmodulin-dependent protein kinase inhibition potentiates thapsigargin-mediated cell death in SH-SY5Y human neuroblastoma cells.
Neuroscience letters 2001;301(2):99-102.
2000: N Mukerjee; Kim M McGinnis; Y H Park; Margaret E Gnegy; Kevin Wang
Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells.
Archives of biochemistry and biophysics 2000;379(2):337-43.
2000: Rita Cowell; Lana Kantor; GH Hewlett; Kirk A Frey; Margaret E Gnegy
Dopamine transporter antagonists block phorbol ester-induced dopamine release and dopamine transporter phosphorylation in striatal synaptosomes.
European journal of pharmacology 2000;389(1):59-65.
2000: Margaret E Gnegy
Ca2+/calmodulin signaling in NMDA-induced synaptic plasticity.
Critical reviews in neurobiology 2000;14(2):91-129.
2000: Sharon Kay Michelhaugh; Margaret E Gnegy
Differential regulation of calmodulin content and calmodulin messenger RNA levels by acute and repeated, intermittent amphetamine in dopaminergic terminal and midbrain areas.
Neuroscience 2000;98(2):275-85.
1999: Kim M McGinnis; Margaret E Gnegy; Y H Park; N Mukerjee; Kevin Wang
Procaspase-3 and poly(ADP)ribose polymerase (PARP) are calpain substrates.
Biochemical and biophysical research communications 1999;263(1):94-9.
1999: Lana Kantor; GH Hewlett; Margaret E Gnegy
Enhanced amphetamine- and K+-mediated dopamine release in rat striatum after repeated amphetamine: differential requirements for Ca2+- and calmodulin-dependent phosphorylation and synaptic vesicles.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(10):3801-8.
1999: Kim M McGinnis; Margaret E Gnegy; Kevin Wang
Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis.
Journal of neurochemistry 1999;72(5):1899-906.
1999: Kim M McGinnis; Kevin Wang; Margaret E Gnegy
Alterations of extracellular calcium elicit selective modes of cell death and protease activation in SH-SY5Y human neuroblastoma cells.
Journal of neurochemistry 1999;72(5):1853-63.
1999: Adam Marc Goldsmith; Margaret E Gnegy
Continuous phosphorylation of GAP-43 and MARCKS by long-term TPA treatment in SK-N-SH human neuroblastoma cells.
Biochimica et biophysica acta 1999;1449(3):269-83.
1998: KE Browman; Lana Kantor; S Richardson; Aldo Badiani; Terry E Robinson; Margaret E Gnegy
Injection of the protein kinase C inhibitor Ro31-8220 into the nucleus accumbens attenuates the acute response to amphetamine: tissue and behavioral studies.
Brain research 1998;814(1-2):112-9.
1998: Sharon Kay Michelhaugh; G Pimputkar; Margaret E Gnegy
Alterations in calmodulin mRNA expression and calmodulin content in rat brain after repeated, intermittent amphetamine.
Brain research. Molecular brain research 1998;62(1):35-42.
1998: Kim M McGinnis; M M Whitton; Margaret E Gnegy; Kevin Wang
Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis.
The Journal of biological chemistry 1998;273(32):19993-20000.
1998: Michelle M Ostrander; J Hartman; Aldo Badiani; Terry E Robinson; Margaret E Gnegy
The effect of environment on the changes in calmodulin in rat brain produced by repeated amphetamine treatment.
Brain research 1998;797(2):339-41.
1998: Lana Kantor; Margaret E Gnegy
Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices.
The Journal of pharmacology and experimental therapeutics 1998;284(2):592-8.
1998: Kim M McGinnis; Zia Shariat-Madar; Margaret E Gnegy
Cytosolic calmodulin is increased in SK-N-SH human neuroblastoma cells due to release of calcium from intracellular stores.
Journal of neurochemistry 1998;70(1):139-46.
1997: S I Iwata; GH Hewlett; S T Ferrell; Lana Kantor; Margaret E Gnegy
Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine.
The Journal of pharmacology and experimental therapeutics 1997;283(3):1445-52.
1997: S Iwata; GH Hewlett; Margaret E Gnegy
Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes.
Synapse (New York, N.Y.) 1997;26(3):281-91.
1997: Zia Shariat-Madar; Adam Marc Goldsmith; Margaret E Gnegy
Effect of continuous phorbol ester treatment on muscarinic receptor-mediated calmodulin redistribution in SK-N-SH neuroblastoma cells.
Journal of neurochemistry 1997;68(1):40-6.
1996: Margaret E Gnegy; GH Hewlett; G Pimputkar
Haloperidol and MK-801 block increases in striatal calmodulin resulting from repeated amphetamine treatment.
Brain research 1996;734(1-2):35-42.
1996: S Iwata; GH Hewlett; S T Ferrell; A J Czernik; Karina Meiri; Margaret E Gnegy
Increased in vivo phosphorylation state of neuromodulin and synapsin I in striatum from rats treated with repeated amphetamine.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1428-34.
1995: Margaret E Gnegy
Calmodulin: effects of cell stimuli and drugs on cellular activation.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 1995;45():33-65.
1994: Margaret E Gnegy; A Agrawal; K Hewlett; E Yeung; S Yee
Repeated haloperidol increases both calmodulin and a calmodulin-binding protein in rat striatum.
Brain research. Molecular brain research 1994;27(2):195-204.
1994: W Walke; J Staple; L Adams; Margaret E Gnegy; K Chahine; Daniel Goldman
Calcium-dependent regulation of rat and chick muscle nicotinic acetylcholine receptor (nAChR) gene expression.
The Journal of biological chemistry 1994;269(30):19447-56.
1993: Margaret E Gnegy; P Hong; S T Ferrell
Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine.
Brain research. Molecular brain research 1993;20(4):289-98.
1993: Margaret E Gnegy
Calmodulin in neurotransmitter and hormone action.
Annual review of pharmacology and toxicology 1993;33():45-70.
1992: L A Mangels; Richard Neubig; H E Hamm; Margaret E Gnegy
Calmodulin binding distinguishes between beta gamma subunits of activated G proteins and transducin.
The Biochemical journal 1992;283 ( Pt 3)():683-90.
1992: L A Mangels; Margaret E Gnegy
Carbachol stimulates binding of a photoreactive calmodulin derivative to calmodulin-binding proteins in intact SK-N-SH human neuroblastoma cells.
The Journal of biological chemistry 1992;267(9):5847-54.
1992: L A Mangels; Margaret E Gnegy
Cyclic AMP accumulation alters calmodulin localization in SK-N-SH human neuroblastoma cells.
Brain research. Molecular brain research 1992;12(1-3):103-10.
1991: Margaret E Gnegy; GH Hewlett; S L Yee; Michael J Welsh
Alterations in calmodulin content and localization in areas of rat brain after repeated intermittent amphetamine.
Brain research 1991;562(1):6-12.
1991: S C Sweet; Margaret E Gnegy; Michael J Welsh
Presence of matrix-specific antibodies in affinity-purified polyclonal antibodies.
Journal of immunological methods 1991;136(1):31-6.
1990: P H Roseboom; GH Hewlett; Margaret E Gnegy
Repeated amphetamine administration alters the interaction between D1-stimulated adenylyl cyclase activity and calmodulin in rat striatum.
The Journal of pharmacology and experimental therapeutics 1990;255(1):197-203.
1990: J M Ackerman; Margaret E Gnegy
Desensitization of the dopaminergic system in bovine retina following incubation with high potassium.
Brain research 1990;521(1-2):296-302.
1990: L A Mangels; Margaret E Gnegy
Muscarinic receptor-mediated translocation of calmodulin in SK-N-SH human neuroblastoma cells.
Molecular pharmacology 1990;37(6):820-6.
1989: J K Harrison; GH Hewlett; Margaret E Gnegy
Regulation of calmodulin-sensitive adenylate cyclase by the stimulatory G-protein, Gs.
The Journal of biological chemistry 1989;264(27):15880-5.
1989: J K Harrison; R G Lawton; Margaret E Gnegy
Development of a novel photoreactive calmodulin derivative: cross-linking of purified adenylate cyclase from bovine brain.
Biochemistry 1989;28(14):6023-7.
1989: T Ryan-Jastrow; Margaret E Gnegy
Castration blocks chronic sulpiride-induced desensitization of striatal D1 receptor-stimulated adenylate cyclase activity in male rats.
The Journal of pharmacology and experimental therapeutics 1989;248(2):626-31.
1989: P H Roseboom; Margaret E Gnegy
Acute in vivo amphetamine produces a homologous desensitization of dopamine receptor-coupled adenylate cyclase activities and decreases agonist binding to the D1 site.
Molecular pharmacology 1989;35(1):139-47.
1988: J K Harrison; C K Mickevicius; Margaret E Gnegy
Differential regulation by calmodulin of basal, GTP-, and dopamine-stimulated adenylate cyclase activities in bovine striatum.
Journal of neurochemistry 1988;51(2):345-52.
1986: C K Mickevicius; J K Harrison; Margaret E Gnegy
Effect of cholera toxin on the activation of adenylate cyclase by calmodulin in bovine striatum.
Molecular pharmacology 1986;30(5):469-75.
1986: J M Roberts-Lewis; Michael J Welsh; Margaret E Gnegy
Chronic amphetamine treatment increases striatal calmodulin in rats.
Brain research 1986;384(2):383-6.
1986: J M Roberts-Lewis; P H Roseboom; L M Iwaniec; Margaret E Gnegy
Differential down-regulation of D1-stimulated adenylate cyclase activity in rat forebrain after in vivo amphetamine treatments.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(8):2245-51.
1986: Glenn J Treisman; N Muirhead; Margaret E Gnegy
Increased sensitivity of adenylate cyclase activity in the striatum of the rat to calmodulin and GppNHp after chronic treatment with haloperidol.
Neuropharmacology 1986;25(6):587-95.
1985: M B Turla; Margaret E Gnegy; S Epps; Marshal Shlafer
Loss of calmodulin activity in cardiac sarcoplasmic reticulum after ischemia.
Biochemical and biophysical research communications 1985;130(2):617-20.
1985: Glenn J Treisman; N Muirhead; L Iwaniec; Margaret E Gnegy
Inhibition of a low Km GTPase activity in rat striatum by calmodulin.
Journal of neurochemistry 1985;44(2):518-25.
1984: Margaret E Gnegy; N Muirhead; J M Roberts-Lewis; Glenn J Treisman
Calmodulin stimulates adenylate cyclase activity and increases dopamine activation in bovine retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(11):2712-7.
1984: T R Jastrow; E Richfield; Margaret E Gnegy
Quantitative autoradiography of [3H]sulpiride binding sites in rat brain.
Neuroscience letters 1984;51(1):47-53.
1984: Margaret E Gnegy; N Muirhead; J K Harrison
Regulation of calmodulin- and dopamine-stimulated adenylate cyclase activities by light in bovine retina.
Journal of neurochemistry 1984;42(6):1632-40.
1983: Glenn J Treisman; S Bagley; Margaret E Gnegy
Calmodulin-sensitive and calmodulin-insensitive components of adenylate cyclase activity in rat striatum have differential responsiveness to guanyl nucleotides.
Journal of neurochemistry 1983;41(5):1398-406.
1983: J A Warth; G J Brewer; Margaret E Gnegy; Glenn J Treisman; K Near
Calmodulin level in whole blood correlates with the percentage of reticulocytes.
American journal of hematology 1983;15(2):153-7.
1983: Margaret E Gnegy; A Bernabei; Glenn J Treisman
Chronic sulpiride treatment produces supersensitivity of striatal adenylate cyclase to dopamine in sexually immature or adult castrated rats.
The Journal of pharmacology and experimental therapeutics 1983;224(3):627-33.
1982: Margaret E Gnegy
Relationship of calmodulin and dopaminergic activity in the striatum.
Federation proceedings 1982;41(7):2273-7.
1982: Y S Lau; Margaret E Gnegy
Chronic haloperidol treatment increased calcium-dependent phosphorylation in rat striatum.
Life sciences 1982;30(1):21-8.
1981: Margaret E Gnegy; R P Erickson; J Markovac
Increased calmodulin in cultured skin fibroblasts from patients with cystic fibrosis.
Biochemical medicine 1981;26(3):294-8.
1981: Margaret E Gnegy; Glenn J Treisman
Effect of calmodulin on dopamine-sensitive adenylate cyclase activity in rat striatal membranes.
Molecular pharmacology 1981;19(2):256-63.
1980: Y S Lau; Margaret E Gnegy
Effects of lanthanum and trifluoperazine on [125I]calmodulin binding to rat striatal particulates.
The Journal of pharmacology and experimental therapeutics 1980;215(1):28-34.
1980: Margaret E Gnegy; Y S Lau
Effects of chronic and acute treatment of antipsychotic drugs on calmodulin release from rat striatal membranes.
Neuropharmacology 1980;19(3):319-23.
1980: Margaret E Gnegy; Y S Lau; Glenn J Treisman
Role of calmodulin in states of altered catecholamine sensitivity.
Annals of the New York Academy of Sciences 1980;356():304-18.
1980: Margaret E Gnegy; E Costa
Catecholamine receptor supersensitivity and subsensitivity in the central nervous system.
Essays in neurochemistry and neuropharmacology 1980;4():249-82.
1980: Margaret E Gnegy; T Hultin; Glenn J Treisman
Effect of calmodulin on catecholamine-linked adenylate cyclase activity in rat striatum and cerebral cortex.
Advances in biochemical psychopharmacology 1980;21():125-31.
1980: Margaret E Gnegy; Y S Lau
Calmodulin release from striatal membranes after acute and chronic treatment with butaclamol.
Advances in biochemical psychopharmacology 1980;24():147-51.
1977: Margaret E Gnegy; A Lucchelli; E Costa
Correlation between drug-induced supersensitivity of dopamine dependent striatal mechanisms and the increase in striatal content of the Ca2+ regulated protein activator of cAMP phosphodiesterase.
Naunyn-Schmiedeberg's archives of pharmacology 1977;301(2):121-7.
1977: Margaret E Gnegy; P Uzunov; E Costa
Participation of an endogenous Ca++-blinding protein activator in the development of drug-induced supersensitivity of striatal dopamine receptors.
The Journal of pharmacology and experimental therapeutics 1977;202(3):558-64.
1977: Margaret E Gnegy; J A Nathanson; P Uzunov
Release of the phosphodiesterase activator by cyclic AMP-dependent ATP:protein phosphotransferase from subcellular fractions of rat brain.
Biochimica et biophysica acta 1977;497(1):75-85.
1977: E Costa; Margaret E Gnegy; P Uzunov
Regulation of dopamine receptor sensitivity by an endogenous protein activator or adenylate cyclase.
Naunyn-Schmiedeberg's archives of pharmacology 1977;297 Suppl 1():S47-8.
1977: E Costa; Margaret E Gnegy; A Revuelta; P Uzunov
Regulation of dopamine-dependent adenylate cyclase by a Ca++ binding protein stored in synaptic membranes.
Advances in biochemical psychopharmacology 1977;16():403-8.
1976: Margaret E Gnegy; P Uzunov
Regulation of dopamine stimulation of striatal adenylate cyclase by an endogenous Ca++ -binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(11):3887-90.
1976: Margaret E Gnegy; F J Lotspeich
Inhibitors of tRNA methyltransferases. S-Adenosylsulfonium salts.
Journal of medicinal chemistry 1976;19(10):1191-5.
1976: P Uzunov; Margaret E Gnegy; A Revuelta; E Costa
Regulation of the high Km cyclic nucleotide phosphodiesterase of adrenal medulla by the endogenous calcium-dependent-protein activator.
Biochemical and biophysical research communications 1976;70(1):132-8.
1976: P Uzunov; R Lehne; A V Revuelta; Margaret E Gnegy; E Costa
A kinetic analysis of the cyclic nucleotide phosphodiesterase regulation by the endogenous protein activator. A study of rat brain and frog sympathetic chain.
Biochimica et biophysica acta 1976;422(2):326-34.
1976: Margaret E Gnegy; E Costa; P Uzunov
Regulation of transsynaptically elicited increase of 3':5'-cyclic AMP by endogenous phosphodiesterase activator.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(2):352-5.
1976: P Uzunov; Margaret E Gnegy; R Lehne; A Revuelta; E Costa
A neurobiological role for a protein activator of cyclic nucleotide phosphodiesterase.
Advances in biochemical psychopharmacology 1976;15():283-301.