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Gary Archer
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49
Bigner, Darell
33
Sampson, John
24
Friedman, Henry
20
McLendon, Roger
17
Zalutsky, Michael
14
Friedman, Allan
11
Heimberger, Amy
10
Wikstrand, Carol
10
Mitchell, Duane
9
Fuchs, Herbert
8
Pastan, Ira
6
Garg, Pradeep
6
Herndon, James
6
Ochiai, Hidenobu
5
Hale, Laura
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All Publications
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2009: Sampson John H; Archer Gary E; Mitchell Duane A; Heimberger Amy B; Herndon James E; Lally-Goss Denise; McGehee-Norman Sharon; Paolino Alison; Reardon David A; Friedman Allan H; Friedman Henry S; Bigner Darell D
An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme.
Molecular cancer therapeutics 2009;8(10):2773-9.
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2009: Choi Bryan D; Archer Gary E; Mitchell Duane A; Heimberger Amy B; McLendon Roger E; Bigner Darell D; Sampson John H
EGFRvIII-targeted vaccination therapy of malignant glioma.
Brain pathology (Zurich, Switzerland) 2009;19(4):713-23.
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2008: Schmittling Robert J; Archer Gary E; Mitchell Duane A; Heimberger Amy; Pegram Charles; Herndon James E; Friedman Henry S; Bigner Darell D; Sampson John H
Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines.
Journal of immunological methods 2008;339(1):74-81.
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2008: Sampson John H; Archer Gary E; Mitchell Duane A; Heimberger Amy B; Bigner Darell D
Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma.
Seminars in immunology 2008;20(5):267-75.
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2008: Kong Ling-Yuan; Abou-Ghazal Mohamed K; Wei Jun; Chakraborty Arup; Sun Wei; Qiao Wei; Fuller Gregory N; Fokt Izabela; Grimm Elizabeth A; Schmittling Robert J; Archer Gary E; Sampson John H; Priebe Waldemar; Heimberger Amy B
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5759-68.
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2008: Sampson John H; Akabani Gamal; Archer Gerald E; Berger Mitchel S; Coleman R Edward; Friedman Allan H; Friedman Henry S; Greer Kim; Herndon James E; Kunwar Sandeep; McLendon Roger E; Paolino Alison; Petry Neil A; Provenzale James M; Reardon David A; Wong Terence Z; Zalutsky Michael R; Pastan Ira; Bigner Darell D
Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors.
Neuro-oncology 2008;10(3):320-9.
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2008: Heimberger Amy B; Sun Wei; Hussain S Farzana; Dey Mahua; Crutcher Lamonne; Aldape Ken; Gilbert Mark; Hassenbusch Samuel J; Sawaya Raymond; Schmittling Bob; Archer Gary E; Mitchell Duane A; Bigner Darell D; Sampson John H
Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study.
Neuro-oncology 2008;10(1):98-103.
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2008: Ochiai Hidenobu; Archer Gary E; Herndon James E; Kuan Chien-Tsun; Mitchell Duane A; Bigner Darell D; Pastan Ira H; Sampson John H
EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells.
Cancer immunology, immunotherapy : CII 2008;57(1):115-21.
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2007: Fecci Peter E; Ochiai Hidenobu; Mitchell Duane A; Grossi Peter M; Sweeney Alison E; Archer Gary E; Cummings Thomas; Allison James P; Bigner Darell D; Sampson John H
Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2158-67.
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2006: Learn Chris A; Fecci Peter E; Schmittling Robert J; Xie Weihua; Karikari Isaac; Mitchell Duane A; Archer Gary E; Wei ZhengZheng; Dressman Holly; Sampson John H
Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7306-15.
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2006: Ochiai Hidenobu; Pernell Chris T; Archer Gary E; Chewning Tracy A; McLendon Roger E; Friedman Henry S; Sampson John H
Treatment of neoplastic meningitis with intrathecal 9-nitro-camptothecin.
Neurologia medico-chirurgica 2006;46(10):485-9; discussion 489-90.
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2006: Fecci Peter E; Mitchell Duane A; Whitesides John F; Xie Weihua; Friedman Allan H; Archer Gary E; Herndon James E; Bigner Darell D; Dranoff Glenn; Sampson John H
Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.
Cancer research 2006;66(6):3294-302.
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2006: Ochiai Hidenobu; Campbell Stephanie A; Archer Gary E; Chewning Tracy A; Dragunsky Eugenia; Ivanov Alexander; Gromeier Matthias; Sampson John H
Targeted therapy for glioblastoma multiforme neoplastic meningitis with intrathecal delivery of an oncolytic recombinant poliovirus.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(4):1349-54.
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2004: Ochiai Hidenobu; Moore Stephanie A; Archer Gary E; Okamura Tatsunori; Chewning Tracy A; Marks Jeffrey R; Sampson John H; Gromeier Matthias
Treatment of intracerebral neoplasia and neoplastic meningitis with regional delivery of oncolytic recombinant poliovirus.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4831-8.
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2004: Learn Chris A; Hartzell Tristan L; Wikstrand Carol J; Archer Gary E; Rich Jeremy N; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3216-24.
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2003: Grossi Peter M; Ochiai Hidenobu; Archer Gary E; McLendon Roger E; Zalutsky Michael R; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Efficacy of intracerebral microinfusion of trastuzumab in an athymic rat model of intracerebral metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5514-20.
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2003: Sampson John H; Akabani Gamal; Archer Gary E; Bigner Darell D; Berger Mitchel S; Friedman Allan H; Friedman Henry S; Herndon James E; Kunwar Sandeep; Marcus Steve; McLendon Roger E; Paolino Alison; Penne Kara; Provenzale James; Quinn Jennifer; Reardon David A; Rich Jeremy; Stenzel Timothy; Tourt-Uhlig Sandra; Wikstrand Carol; Wong Terence; Williams Roger; Yuan Fan; Zalutsky Michael R; Pastan Ira
Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors.
Journal of neuro-oncology 2003;65(1):27-35.
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2003: Heimberger Amy B; Crotty Laura E; Archer Gary E; Hess Kenneth R; Wikstrand Carol J; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Epidermal growth factor receptor VIII peptide vaccination is efficacious against established intracerebral tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(11):4247-54.
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2003: Fecci Peter E; Mitchell Duane A; Archer Gary E; Morse Michael A; Lyerly H Kim; Bigner Darell D; Sampson John H
The history, evolution, and clinical use of dendritic cell-based immunization strategies in the therapy of brain tumors.
Journal of neuro-oncology 2003;64(1-2):161-76.
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2002: Heimberger Amy B; Learn Chris A; Archer Gary E; McLendon Roger E; Chewning Tracy A; Tuck Frank L; Pracyk John B; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3496-502.
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2002: Lal Anita; Glazer Chad A; Martinson Holly M; Friedman Henry S; Archer Gary E; Sampson John H; Riggins Gregory J
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
Cancer research 2002;62(12):3335-9.
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2002: Heimberger Amy B; Archer Gary E; Crotty Laura E; McLendon Roger E; Friedman Allan H; Friedman Henry S; Bigner Darell D; Sampson John H
Dendritic cells pulsed with a tumor-specific peptide induce long-lasting immunity and are effective against murine intracerebral melanoma.
Neurosurgery 2002;50(1):158-64; discussion 164-6.
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2000: Kuan C T; Wikstrand C J; Archer G; Beers R; Pastan I; Zalutsky M R; Bigner D D
Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII-specific scFv.
International journal of cancer. Journal international du cancer 2000;88(6):962-9.
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2000: Heimberger A B; Archer G E; McLendon R E; Hulette C; Friedman A H; Friedman H S; Bigner D D; Sampson J H
Temozolomide delivered by intracerebral microinfusion is safe and efficacious against malignant gliomas in rats.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):4148-53.
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2000: Sampson J H; Crotty L E; Lee S; Archer G E; Ashley D M; Wikstrand C J; Hale L P; Small C; Dranoff G; Friedman A H; Friedman H S; Bigner D D
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7503-8.
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2000: Heimberger A B; Crotty L E; Archer G E; McLendon R E; Friedman A; Dranoff G; Bigner D D; Sampson J H
Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma.
Journal of neuroimmunology 2000;103(1):16-25.
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1999: Archer G E; Sampson J H; Lorimer I A; McLendon R E; Kuan C T; Friedman A H; Friedman H S; Pastan I H; Bigner D D
Regional treatment of epidermal growth factor receptor vIII-expressing neoplastic meningitis with a single-chain immunotoxin, MR-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2646-52.
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1999: McLendon R E; Archer G E; Larsen R H; Akabani G; Bigner D D; Zalutsky M R
Radiotoxicity of systemically administered 211At-labeled human/mouse chimeric monoclonal antibody: a long-term survival study with histologic analysis.
International journal of radiation oncology, biology, physics 1999;45(2):491-9.
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1999: Kuan C T; Reist C J; Foulon C F; Lorimer I A; Archer G; Pegram C N; Pastan I; Zalutsky M R; Bigner D D
125I-labeled anti-epidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(6):1539-49.
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1999: Sampson J H; Archer G E; Villavicencio A T; McLendon R E; Friedman A H; Bishop W R; Bigner D D; Friedman H S
Treatment of neoplastic meningitis with intrathecal temozolomide.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(5):1183-8.
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1999: Archer G E; Sampson J H; McLendon R E; Friedman A H; Colvin O M; Rose M; Sands H; McCullough W; Fuchs H E; Bigner D D; Friedman H S
Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats.
Journal of neuro-oncology 1999;44(3):233-41.
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1998: Ashley D M; Sampson J H; Archer G E; Hale L P; Bigner D D
Local production of TGF beta1 inhibits cerebral edema, enhances TNF-alpha induced apoptosis and improves survival in a murine glioma model.
Journal of neuroimmunology 1998;86(1):46-52.
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1998: Wikstrand C J; Reist C J; Archer G E; Zalutsky M R; Bigner D D
The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target.
Journal of neurovirology 1998;4(2):148-58.
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1997: Sampson J H; Ashley D M; Archer G E; Fuchs H E; Dranoff G; Hale L P; Bigner D D
Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion.
Neurosurgery 1997;41(6):1365-72; discussion 1372-3.
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1997: Ashley D M; Sampson J H; Archer G E; Batra S K; Bigner D D; Hale L P
A genetically modified allogeneic cellular vaccine generates MHC class I-restricted cytotoxic responses against tumor-associated antigens and protects against CNS tumors in vivo.
Journal of neuroimmunology 1997;78(1-2):34-46.
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1997: Archer G E; Sampson J H; Bigner D D
Viruses and oncogenes in brain tumors.
Journal of neurovirology 1997;3 Suppl 1():S76-7.
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1997: Reist C J; Archer G E; Wikstrand C J; Bigner D D; Zalutsky M R
Improved targeting of an anti-epidermal growth factor receptor variant III monoclonal antibody in tumor xenografts after labeling using N-succinimidyl 5-iodo-3-pyridinecarboxylate.
Cancer research 1997;57(8):1510-5.
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1996: Sampson J H; Archer G E; Ashley D M; Fuchs H E; Hale L P; Dranoff G; Bigner D D
Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10399-404.
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1996: Zalutsky M R; Archer G E; Garg P K; Batra S K; Bigner D D
Chimeric anti-tenascin antibody 81C6: increased tumor localization compared with its murine parent.
Nuclear medicine and biology 1996;23(4):449-58.
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1996: McLendon R E; Archer G E; Garg P K; Bigner D D; Zalutsky M R
Radiotoxicity of systematically administered [211At]astatide in B6C3F1 and BALB/c (nu/nu) mice: a long-term survival study with histologic analysis.
International journal of radiation oncology, biology, physics 1996;35(1):69-80.
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1996: Zalutsky M R; Schuster J M; Garg P K; Archer G E; Dewhirst M W; Bigner D D
Two approaches for enhancing radioimmunotherapy: alpha emitters and hyperthermia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1996;141():101-22.
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1995: Bigner D D; Archer G E; McLendon R E; Friedman H S; Fuchs H E; Pai L H; Herndon J E; Pastan I H
Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1545-55.
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1995: Reist C J; Archer G E; Kurpad S N; Wikstrand C J; Vaidyanathan G; Willingham M C; Moscatello D K; Wong A J; Bigner D D; Zalutsky M R
Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts.
Cancer research 1995;55(19):4375-82.
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1995: Kurpad S N; Friedman H S; Archer G E; McLendon R E; Petros W M; Fuchs H E; Guaspari A; Bigner D D
Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats.
Cancer research 1995;55(17):3803-9.
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1995: Pastan I H; Archer G E; McLendon R E; Friedman H S; Fuchs H E; Wang Q C; Pai L H; Herndon J; Bigner D D
Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2765-9.
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1994: Page R L; Garg P K; Garg S; Archer G E; Bruland O S; Zalutsky M R
PET imaging of osteosarcoma in dogs using a fluorine-18-labeled monoclonal antibody Fab fragment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(9):1506-13.
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1994: Zalutsky M R; McLendon R E; Garg P K; Archer G E; Schuster J M; Bigner D D
Radioimmunotherapy of neoplastic meningitis in rats using an alpha-particle-emitting immunoconjugate.
Cancer research 1994;54(17):4719-25.
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1994: Friedman H S; Archer G E; McLendon R E; Schuster J M; Colvin O M; Guaspari A; Blum R; Savina P A; Fuchs H E; Bigner D D
Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats.
Cancer research 1994;54(17):4710-4.
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1994: He X; Archer G E; Wikstrand C J; Morrison S L; Zalutsky M R; Bigner D D; Batra S K
Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascin.
Journal of neuroimmunology 1994;52(2):127-37.
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1993: Wikstrand C J; Stanley S D; Humphrey P A; Pegram C N; Archer G E; Kurpad S; Shibuya M; Bigner D D
Investigation of a synthetic peptide as immunogen for a variant epidermal growth factor receptor associated with gliomas.
Journal of neuroimmunology 1993;46(1-2):165-73.
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1993: Schuster J M; Friedman H S; Archer G E; Fuchs H E; McLendon R E; Colvin O M; Bigner D D
Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydroperoxycyclophosphamide.
Cancer research 1993;53(10 Suppl):2338-43.
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1991: Humphrey P A; Gangarosa L M; Wong A J; Archer G E; Lund-Johansen M; Bjerkvig R; Laerum O D; Friedman H S; Bigner D D
Deletion-mutant epidermal growth factor receptor in human gliomas: effects of type II mutation on receptor function.
Biochemical and biophysical research communications 1991;178(3):1413-20.
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1990: Humphrey P A; Wong A J; Vogelstein B; Zalutsky M R; Fuller G N; Archer G E; Friedman H S; Kwatra M M; Bigner S H; Bigner D D
Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4207-11.
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1990: Colapinto E V; Zalutsky M R; Archer G E; Noska M A; Friedman H S; Carrel S; Bigner D D
Radioimmunotherapy of intracerebral human glioma xenografts with 131I-labeled F(ab')2 fragments of monoclonal antibody Mel-14.
Cancer research 1990;50(6):1822-7.
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1990: Fuchs H E; Archer G E; Colvin O M; Bigner S H; Schuster J M; Fuller G N; Muhlbaier L H; Schold S C; Friedman H S; Bigner D D
Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis.
Cancer research 1990;50(6):1954-9.
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1989: Garg P K; Archer G E; Bigner D D; Zalutsky M R
Synthesis of radioiodinated N-succinimidyl iodobenzoate: optimization for use in antibody labelling.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1989;40(6):485-90.
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