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David Goeddel

Research Profile

Chemicals & Drugs

Physiology

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Publications

TOP 3
Qilin Pan; Vladimir V Kravchenko; Alex Katz; Shuang Huang; Masayuki Ii; John C Mathison; Koichi Kobayashi; Richard A Flavell; Robert D Schreiber; David V Goeddel; Richard J Ulevitch
NF-kappa B-inducing kinase regulates selected gene expression in the Nod2 signaling pathway.
David V Goeddel; Lianhe Shu; Yi Yuan; O Andrea Wong; Bin Wang; Yian Shi
Effective asymmetric epoxidation of styrenes by chiral dioxirane.
Dietrich B Conze; Lori Albert; David A Ferrick; David V Goeddel; Wen-Chen Yeh; Tak Mak; Jonathan D Ashwell
Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo.

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All Publications

2006: Qilin Pan; Vladimir V Kravchenko; Alex Katz; Shuang Huang; Masayuki Ii; John C Mathison; Koichi Kobayashi; Richard A Flavell; Robert D Schreiber; David V Goeddel; Richard J Ulevitch
NF-kappa B-inducing kinase regulates selected gene expression in the Nod2 signaling pathway.
Infection and immunity 2006;74(4):2121-7.
2006: David V Goeddel; Lianhe Shu; Yi Yuan; O Andrea Wong; Bin Wang; Yian Shi
Effective asymmetric epoxidation of styrenes by chiral dioxirane.
The Journal of organic chemistry 2006;71(4):1715-7.
2005: Dietrich B Conze; Lori Albert; David A Ferrick; David V Goeddel; Wen-Chen Yeh; Tak Mak; Jonathan D Ashwell
Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo.
Molecular and cellular biology 2005;25(8):3348-56.
2004: Matthew Hickey; David V Goeddel; Zackary Crane; Yian Shi
Highly enantioselective epoxidation of styrenes: implication of an electronic effect on the competition between spiro and planar transition states.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):5794-8.
2003: Deborah Veis Novack; Li Yin; Amanda Hagen-Stapleton; Robert D Schreiber; David V Goeddel; F Patrick Ross; Steven L Teitelbaum
The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis.
The Journal of experimental medicine 2003;198(5):771-81.
2003: Lianhe Shu; Yu-Mei Shen; Christopher Burke; David V Goeddel; Yian Shi
An improved synthesis of a ketone catalyst for asymmetric epoxidation of olefins.
The Journal of organic chemistry 2003;68(12):4963-5.
2002: Guoqing Chen; David V Goeddel
TNF-R1 signaling: a beautiful pathway.
Science (New York, N.Y.) 2002;296(5573):1634-5.
2002: Guoqing Chen; Ping Cao; David V Goeddel
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90.
Molecular cell 2002;9(2):401-10.
2001: L Yin; L Wu; H Wesche; C D Arthur; J M White; David V Goeddel; Robert D Schreiber
Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.
Science (New York, N.Y.) 2001;291(5511):2162-5.
2000: Wen-Chen Yeh; Annick Itie; Andrew Elia; M Ng; HB Shu; Andrew Wakeham; Christine Mirtsos; Nobutaka Suzuki; Madeleine Bonnard; David V Goeddel; Tak W Mak
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development.
Immunity 2000;12(6):633-42.
1999: Mark A Lomaga; Wen-Chen Yeh; Ildiko Sarosi; Gordon S Duncan; Caren Furlonger; Alexandra Ho; Sean Morony; Charles Capparelli; Gwyneth Van; Stephen Kaufman; A van der Heiden; Annick Itie; Andrew Wakeham; W Khoo; Takehiko Sasaki; Z Cao; Josef M Penninger; Christopher J Paige; David L Lacey; Colin R Dunstan; william boyle; David V Goeddel; Tak W Mak
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling.
Genes & development 1999;13(8):1015-24.
1999: M Tanaka; M E Fuentes; K Yamaguchi; M H Durnin; S A Dalrymple; K L Hardy; David V Goeddel
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice.
Immunity 1999;10(4):421-9.
1999: Y Jiang; JD Woronicz; W Liu; David V Goeddel
Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.
Science (New York, N.Y.) 1999;283(5401):543-6.
1999: Z Cao; M Tanaka; C Regnier; M Rothe; A Yamit-hezi; JD Woronicz; M E Fuentes; M H Durnin; S A Dalrymple; David V Goeddel
NF-kappa B activation by tumor necrosis factor and interleukin-1.
Cold Spring Harbor symposia on quantitative biology 1999;64():473-83.
1998: Wen-Chen Yeh; J L Pompa; Mila E McCurrach; HB Shu; Andrew Elia; Arda Shahinian; M Ng; Andrew Wakeham; W Khoo; K Mitchell; Wafik S El-Deiry; Scott W Lowe; David V Goeddel; Tak W Mak
FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis.
Science (New York, N.Y.) 1998;279(5358):1954-8.
1997: Wen-Chen Yeh; Arda Shahinian; D Speiser; J Kraunus; Filio Billia; Andrew Wakeham; José Luis de la Pompa; David A Ferrick; B Hum; Norman N Iscove; Pamela S Ohashi; M Rothe; David V Goeddel; Tak W Mak
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice.
Immunity 1997;7(5):715-25.
1997: JD Woronicz; X Gao; Z Cao; M Rothe; David V Goeddel
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK.
Science (New York, N.Y.) 1997;278(5339):866-9.
1997: H Y Song; C H Régnier; Carsten J Kirschning; David V Goeddel; M Rothe
Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9792-6.
1997: C H Régnier; H Y Song; X Gao; David V Goeddel; Z Cao; M Rothe
Identification and characterization of an IkappaB kinase.
Cell 1997;90(2):373-83.
1997: HB Shu; D R Halpin; David V Goeddel
Casper is a FADD- and caspase-related inducer of apoptosis.
Immunity 1997;6(6):751-63.
1996: H Hsu; J Huang; H B Shu; V Baichwal; David V Goeddel
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex.
Immunity 1996;4(4):387-96.
1996: H Hsu; H B Shu; M G Pan; David V Goeddel
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.
Cell 1996;84(2):299-308.
1996: David V Goeddel
Tumor necrosis factor signaling mechanisms.
Harvey lectures 1996;92():41-54.
1995: G E Croston; Z Cao; David V Goeddel
NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity.
The Journal of biological chemistry 1995;270(28):16514-7.
1995: H Hsu; J Xiong; David V Goeddel
The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation.
Cell 1995;81(4):495-504.