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Michel Goedert

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Florence Clavaguera; Ben Falcon; Stephan Frank; Michel Goedert; Isabelle Lavenir; Markus Tolnay
"Prion-like" templated misfolding in tauopathies.
Kyle L Morris; Lin Chen; Michel Goedert; Pawel Sikorski; Shahin Zibaee; Louise C Serpell
The structure of cross-β tapes and tubes formed by an octapeptide, αSβ1.
Sefika Ozcelik; Véronique Schaeffer; Michael Sinnreich; Zhiva Skachokova; Markus Tolnay; Karin Breu; Perrine Castets; Florence Clavaguera; Graham Fraser; Michel Goedert; Ludwig Kappos; David Theo Winkler
Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice.

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All Publications

2013: Florence Clavaguera; Ben Falcon; Stephan Frank; Michel Goedert; Isabelle Lavenir; Markus Tolnay
"Prion-like" templated misfolding in tauopathies.
Brain pathology (Zurich, Switzerland) 2013;23(3):342-9.
2013: Kyle L Morris; Lin Chen; Michel Goedert; Pawel Sikorski; Shahin Zibaee; Louise C Serpell
The structure of cross-β tapes and tubes formed by an octapeptide, αSβ1.
Angewandte Chemie (International ed. in English) 2013;52(8):2279-83.
2013: Sefika Ozcelik; Véronique Schaeffer; Michael Sinnreich; Zhiva Skachokova; Markus Tolnay; Karin Breu; Perrine Castets; Florence Clavaguera; Graham Fraser; Michel Goedert; Ludwig Kappos; David Theo Winkler
Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice.
PloS one 2013;8(5):e62459.
2013: Michel Goedert; Maria Grazia Spillantini; Kelly Del Tredici; Heiko Braak
100 years of Lewy pathology.
Nature reviews. Neurology 2013;9(1):13-24.
2012: Véronique Schaeffer; Michel Goedert
Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy.
Autophagy 2012;8(11):1686-7.
2012: Véronique Schaeffer; Markus Tolnay; David T Winkler; Isabelle Lavenir; Sefika Ozcelik; Michel Goedert
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy.
Brain : a journal of neurology 2012;135(Pt 7):2169-77.
2012: Michel Goedert; Bernardino Ghetti; Maria Grazia Spillantini
Frontotemporal dementia: implications for understanding Alzheimer disease.
Cold Spring Harbor perspectives in medicine 2012;2(2):a006254.
2012: Christian Schön; Mathias W Seeliger; Sonja Steinbach; Thomas Arzberger; Steffen Burgold; Severin Filser; Michel Goedert; Nadine A Hoffmann; Hans A Kretzschmar; Simon M Ochs; Boris Schmidt; Jochen Herms
Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice.
PloS one 2012;7(12):e53547.
2012: Natalie D Bull; Michel Goedert; Alessandra Guidi; Keith R Martin; Maria Grazia Spillantini
Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau.
PloS one 2012;7(4):e34724.
2011: Michel Goedert; Maria Grazia Spillantini
Pathogenesis of the tauopathies.
Journal of molecular neuroscience : MN 2011;45(3):425-31.
2011: Laura Gasparini; R Anthony Crowther; Keith R Martin; Nicola Berg; Michael Coleman; Michel Goedert; Maria Grazia Spillantini
Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability.
Neurobiology of aging 2011;32(3):419-33.
2010: Shahin Zibaee; Graham Fraser; Ross Jakes; David Owen; Louise C Serpell; R Anthony Crowther; Michel Goedert
Human beta-synuclein rendered fibrillogenic by designed mutations.
The Journal of biological chemistry 2010;285(49):38555-67.
2010: David W Hampton; Daniel J Webber; Bilada Bilican; Michel Goedert; Maria Grazia Spillantini; Siddharthan Chandran
Cell-mediated neuroprotection in a mouse model of human tauopathy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(30):9973-83.
2010: Pablo Garcia-Reitböck; Oleg Anichtchik; Arianna Bellucci; Mariangela Iovino; Chiara Ballini; Elena Fineberg; Bernardino Ghetti; Laura Della Corte; PierFranco Spano; George K Tofaris; Michel Goedert; Maria Grazia Spillantini
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease.
Brain : a journal of neurology 2010;133(Pt 7):2032-44.
2010: Michel Goedert; Florence Clavaguera; Markus Tolnay
The propagation of prion-like protein inclusions in neurodegenerative diseases.
Trends in neurosciences 2010;33(7):317-25.
2010: Janaky Coomaraswamy; Ellen Kilger; Heidrun Wölfing; Claudia Schäfer; Stephan A Kaeser; Bettina M Wegenast-Braun; Jasmin K Hefendehl; Hartwig Wolburg; Matthew Mazzella; Jorge Ghiso; Michel Goedert; Haruhiko Akiyama; Francisco Garcia-Sierra; David P Wolfer; Paul Mathews; Mathias Jucker
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(17):7969-74.
2010: Maria Luisa Scattoni; Laura Gasparini; Enrico Alleva; Michel Goedert; Gemma Calamandrei; Maria Grazia Spillantini
Early behavioural markers of disease in P301S tau transgenic mice.
Behavioural brain research 2010;208(1):250-7.
2010: Béatrice Chambraud; Elodie Sardin; Jérôme Giustiniani; Omar Dounane; Michael Schumacher; Michel Goedert; Etienne Baulieu
A role for FKBP52 in Tau protein function.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(6):2658-63.
2010: Florence Clavaguera; Michel Goedert; Markus Tolnay
[Induction and spreading of tau pathology in a mouse model of Alzheimer's disease].
Médecine sciences : M/S 2010;26(2):121-4.
2009: Makiko Yamashita; Takashi Nonaka; Tetsuaki Arai; Fuyuki Kametani; Vladimir L Buchman; Natalia Ninkina; Sergey O Bachurin; Haruhiko Akiyama; Michel Goedert; Masato Hasegawa
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.
FEBS letters 2009;583(14):2419-24.
2009: Florence Clavaguera; Tristan Bolmont; R Anthony Crowther; Dorothee Abramowski; Stephan Frank; Alphonse Probst; Graham Fraser; Anna K Stalder; Martin Beibel; Matthias Staufenbiel; Mathias Jucker; Michel Goedert; Markus Tolnay
Transmission and spreading of tauopathy in transgenic mouse brain.
Nature cell biology 2009;11(7):909-13.
2009: Michel Goedert
Oskar Fischer and the study of dementia.
Brain : a journal of neurology 2009;132(Pt 4):1102-11.
2009: Masami Masuda; Masato Hasegawa; Takashi Nonaka; Takayuki Oikawa; Motokuni Yonetani; Yoshiki Yamaguchi; Koichi Kato; Shin-ichi Hisanaga; Michel Goedert
Inhibition of alpha-synuclein fibril assembly by small molecules: analysis using epitope-specific antibodies.
FEBS letters 2009;583(4):787-91.
2008: Gabor Geza Kovacs; Katalin Majtenyi; Salvatore Spina; Jill R Murrell; Ellen Gelpi; Romana Hoftberger; Graham Fraser; R Anthony Crowther; Michel Goedert; Herbert Budka; Bernardino Ghetti
White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration.
Journal of neuropathology and experimental neurology 2008;67(10):963-75.
2008: Liang Ye; Ana Velasco; Graham Fraser; Thomas Beach; Lucia Sue; Tracy Osredkar; Vincenzo Libri; Maria Grazia Spillantini; Michel Goedert; ANDREW LOCKHART
In vitro high affinity alpha-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain.
Journal of neurochemistry 2008;105(4):1428-37.
2008: Ana Velasco; Graham Fraser; Patrice Delobel; Bernardino Ghetti; Isabelle Lavenir; Michel Goedert
Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene].
FEBS letters 2008;582(6):901-6.
2008: Rebecca Radde; Cecilia Duma; Michel Goedert; Mathias Jucker
The value of incomplete mouse models of Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2008;35 Suppl 1():S70-4.
2008: Patrice Delobel; Isabelle Lavenir; Graham Fraser; Esther Ingram; Max Holzer; Bernardino Ghetti; Maria Grazia Spillantini; R Anthony Crowther; Michel Goedert
Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy.
The American journal of pathology 2008;172(1):123-31.
2008: Salvatore Spina; Martin R Farlow; Frederick W Unverzagt; David A Kareken; Jill R Murrell; Graham Fraser; Francine Epperson; R Anthony Crowther; Maria Grazia Spillantini; Michel Goedert; Bernardino Ghetti
The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family.
Brain : a journal of neurology 2008;131(Pt 1):72-89.
2007: Shahin Zibaee; Ross Jakes; Graham Fraser; Louise C Serpell; R Anthony Crowther; Michel Goedert
Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein.
Journal of molecular biology 2007;374(2):454-64.
2007: Enrico Magnani; Juan Fan; Laura Gasparini; Matthew Golding; Meredith Williams; Giampietro Schiavo; Michel Goedert; Linda Amos; Maria Grazia Spillantini
Interaction of tau protein with the dynactin complex.
The EMBO journal 2007;26(21):4546-54.
2007: Aasami Ishii; Takashi Nonaka; Sayuri Taniguchi; Taro Saito; Tetsuaki Arai; D M A Mann; Takeshi Iwatsubo; Shin-ichi Hisanaga; Michel Goedert; Masato Hasegawa
Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies.
FEBS letters 2007;581(24):4711-7.
2007: Kanwar Virdee; Hirotaka Yoshida; Sew-Yeu Peak Chew; Michel Goedert
Phosphorylation of human microtubule-associated protein tau by protein kinases of the AGC subfamily.
FEBS letters 2007;581(14):2657-62.
2007: Shahin Zibaee; O Sumner Makin; Michel Goedert; Louise C Serpell
A simple algorithm locates beta-strands in the amyloid fibril core of alpha-synuclein, Abeta, and tau using the amino acid sequence alone.
Protein science : a publication of the Protein Society 2007;16(5):906-18.
2007: Salvatore Spina; Jill R Murrell; Hirotaka Yoshida; Bernardino Ghetti; Niamh Bermingham; Brian Sweeney; Stephen R Dlouhy; R Anthony Crowther; Michel Goedert; Catherine Keohane
The novel Tau mutation G335S: clinical, neuropathological and molecular characterization.
Acta neuropathologica 2007;113(4):461-70.
2007: Michel Goedert; Bernardino Ghetti
Alois Alzheimer: his life and times.
Brain pathology (Zurich, Switzerland) 2007;17(1):57-62.
2006: Kerensa Broersen; Daan van den Brink; Graham Fraser; Michel Goedert; Bazbek Davletov
Alpha-synuclein adopts an alpha-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation.
Biochemistry 2006;45(51):15610-6.
2006: Michel Goedert; Maria Grazia Spillantini
A century of Alzheimer's disease.
Science (New York, N.Y.) 2006;314(5800):777-81.
2006: Michel Goedert; Maria Grazia Spillantini
Frontotemporal lobar degeneration through loss of progranulin function.
Brain : a journal of neurology 2006;129(Pt 11):2808-10.
2006: Hirotaka Yoshida; Michel Goedert
Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope.
Journal of neurochemistry 2006;99(1):154-64.
2006: Masami Masuda; Nobuyuki Suzuki; Sayuri Taniguchi; Takayuki Oikawa; Takashi Nonaka; Takeshi Iwatsubo; Shin-ichi Hisanaga; Michel Goedert; Masato Hasegawa
Small molecule inhibitors of alpha-synuclein filament assembly.
Biochemistry 2006;45(19):6085-94.
2006: George K Tofaris; Pablo Garcia Reitböck; Trevor Humby; Sarah L Lambourne; Mark O'Connell; Bernardino Ghetti; Helen Gossage; Piers C Emson; Lawrence S Wilkinson; Michel Goedert; Maria Grazia Spillantini
Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(15):3942-50.
2006: Masami Masuda; Naoshi Dohmae; Takashi Nonaka; Takayuki Oikawa; Shin-ichi Hisanaga; Michel Goedert; Masato Hasegawa
Cysteine misincorporation in bacterially expressed human alpha-synuclein.
FEBS letters 2006;580(7):1775-9.
2006: Patrice Delobel; Isabelle Lavenir; Bernardino Ghetti; Max Holzer; Michel Goedert
Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1.
The American journal of pathology 2006;168(3):878-87.
2006: Hirotaka Yoshida; Molly Craxton; Ross Jakes; Shahin Zibaee; Richard Tavaré; Graham Fraser; Louise C Serpell; Bazbek Davletov; R Anthony Crowther; Michel Goedert
Synuclein proteins of the pufferfish Fugu rubripes: sequences and functional characterization.
Biochemistry 2006;45(8):2599-607.
2006: Maria Grazia Spillantini; Jill R Murrell; Michel Goedert; Martin R Farlow; Aaron Klug; Bernardino Ghetti
Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD).
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):373-80.
2006: Michel Goedert; Aaron Klug; R Anthony Crowther
Tau protein, the paired helical filament and Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):195-207.
2005: Keiji Yamaguchi; Elizabeth J Cochran; Jill R Murrell; Mihael H Polymeropoulos; Kathleen M Shannon; R Anthony Crowther; Michel Goedert; Bernardino Ghetti
Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the alpha-synuclein gene.
Acta neuropathologica 2005;110(3):298-305.
2005: Michel Goedert
Tau gene mutations and their effects.
Movement disorders : official journal of the Movement Disorder Society 2005;20 Suppl 12():S45-52.
2005: Guadalupe Sabio; J Simon C Arthur; Yvonne Kuma; Mark Peggie; Julia Carr; Victoria Murray-Tait; Francisco Centeno; Michel Goedert; Nick A Morrice; Ana Cuenda
p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP.
The EMBO journal 2005;24(6):1134-45.
2005: Sayuri Taniguchi; Nobuyuki Suzuki; Masami Masuda; Shin-ichi Hisanaga; Takeshi Iwatsubo; Michel Goedert; Masato Hasegawa
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins.
The Journal of biological chemistry 2005;280(9):7614-23.
2005: Carmen Feijoo; David G Campbell; Ross Jakes; Michel Goedert; Ana Cuenda
Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly.
Journal of cell science 2005;118(Pt 2):397-408.
2005: Michel Goedert; Ross Jakes
Mutations causing neurodegenerative tauopathies.
Biochimica et biophysica acta 2005;1739(2-3):240-50.
2004: Arianna Bellucci; Andrew J Westwood; Esther Ingram; Fiorella Casamenti; Michel Goedert; Maria Grazia Spillantini
Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein.
The American journal of pathology 2004;165(5):1643-52.
2004: Max Holzer; Molly Craxton; Ross Jakes; Thomas Arendt; Michel Goedert
Tau gene (MAPT) sequence variation among primates.
Gene 2004;341():313-22.
2004: Woong Choi; Shahin Zibaee; Ross Jakes; Louise C Serpell; Bazbek Davletov; R Anthony Crowther; Michel Goedert
Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein.
FEBS letters 2004;576(3):363-8.
2004: Hirotaka Yoshida; C James Hastie; Hilary McLauchlan; Philip Cohen; Michel Goedert
Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).
Journal of neurochemistry 2004;90(2):352-8.
2004: Philip Cohen; Michel Goedert
GSK3 inhibitors: development and therapeutic potential.
Nature reviews. Drug discovery 2004;3(6):479-87.
2004: Guadalupe Sabio; Suzana Reuver; Carmen Feijoo; Masato Hasegawa; Gareth M Thomas; Francisco Centeno; Sven Kuhlendahl; Sergio Leal-Ortiz; Michel Goedert; Craig Garner; Ana Cuenda
Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2.
The Biochemical journal 2004;380(Pt 1):19-30.
2004: Masaki Takao; Bernardino Ghetti; Hirotaka Yoshida; Pedro Piccardo; Yolanda Narain; Jill R Murrell; Ruben Vidal; Bradley S Glazier; Ross Jakes; Miho Tsutsui; Maria Grazia Spillantini; R Anthony Crowther; Michel Goedert; Atsuo Koto
Early-onset dementia with Lewy bodies.
Brain pathology (Zurich, Switzerland) 2004;14(2):137-47.
2004: Michel Goedert
Tau protein and neurodegeneration.
Seminars in cell & developmental biology 2004;15(1):45-9.
2003: Esther van Herpen; Sonia M Rosso; Lies-Anne Serverijnen; Hirotaka Yoshida; Guido J Breedveld; Raoul van de Graaf; Wouter Kamphorst; Rivka Ravid; Rob Willemsen; Dennis Dooijes; Danielle Majoor-Krakauer; Johan M Kros; R Anthony Crowther; Michel Goedert; Peter Heutink; John C van Swieten
Variable phenotypic expression and extensive tau pathology in two families with the novel tau mutation L315R.
Annals of neurology 2003;54(5):573-81.
2003: Michel Goedert
Neurodegenerative tauopathy in the worm.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9653-5.
2003: John Berriman; Louise C Serpell; Keith A Oberg; Anthony L Fink; Michel Goedert; R Anthony Crowther
Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):9034-8.
2003: Santwana Kar; Juan Fan; Michael J Smith; Michel Goedert; Linda Amos
Repeat motifs of tau bind to the insides of microtubules in the absence of taxol.
The EMBO journal 2003;22(1):70-7.
2002: Hirotaka Yoshida; Michel Goedert
Molecular cloning and functional characterization of chicken brain tau: isoforms with up to five tandem repeats.
Biochemistry 2002;41(51):15203-11.
2002: Bridget Allen; Esther Ingram; Masaki Takao; Michael J Smith; Ross Jakes; Kanwar Virdee; Hirotaka Yoshida; Max Holzer; Molly Craxton; Piers C Emson; Cristiana Atzori; antonio migheli; R Anthony Crowther; Bernardino Ghetti; Maria Grazia Spillantini; Michel Goedert
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(21):9340-51.
2002: Della C David; Robert Layfield; Louise C Serpell; Yolanda Narain; Michel Goedert; Maria Grazia Spillantini
Proteasomal degradation of tau protein.
Journal of neurochemistry 2002;83(1):176-85.
2002: Vladimir Uversky; Jie Li; Pierre O Souillac; Ian S Millett; Sebastian Doniach; Ross Jakes; Michel Goedert; Anthony L Fink
Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins.
The Journal of biological chemistry 2002;277(14):11970-8.
2002: Valérie Buée-Scherrer; Michel Goedert
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases in intact cells.
FEBS letters 2002;515(1-3):151-4.
2002: Patrice Delobel; Stéphane Flament; Malika Hamdane; Ross Jakes; Arlette Rousseau; André Delacourte; Jean-Pierre Vilain; Michel Goedert; Luc BUEE
Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation.
The Journal of biological chemistry 2002;277(11):9199-205.
2002: Sonia M Rosso; Esther van Herpen; Wout Deelen; Wouter Kamphorst; Lies-Anne Severijnen; Rob Willemsen; Rivka Ravid; Martinus F Niermeijer; Dennis Dooijes; Michael J Smith; Michel Goedert; Peter Heutink; John C van Swieten
A novel tau mutation, S320F, causes a tauopathy with inclusions similar to those in Pick's disease.
Annals of neurology 2002;51(3):373-6.
2002: Hirotaka Yoshida; R Anthony Crowther; Michel Goedert
Functional effects of tau gene mutations deltaN296 and N296H.
Journal of neurochemistry 2002;80(3):548-51.
2002: Christopher D Syme; Ewan W Blanch; Carl Holt; Ross Jakes; Michel Goedert; Lutz Hecht; Laurence D Barron
A Raman optical activity study of rheomorphism in caseins, synucleins and tau. New insight into the structure and behaviour of natively unfolded proteins.
European journal of biochemistry / FEBS 2002;269(1):148-56.
2001: Maria Grazia Spillantini; Michel Goedert
Tau and Parkinson disease.
JAMA : the journal of the American Medical Association 2001;286(18):2324-6.
2001: Manuela Neumann; Walter Schulz-Schaeffer; R A Crowther; M J Smith; Maria Grazia Spillantini; Michel Goedert; Hans A Kretzschmar
Pick's disease associated with the novel Tau gene mutation K369I.
Annals of neurology 2001;50(4):503-13.
2001: AM Hartmann; Dan Rujescu; Thomas Giannakouros; Eleni Nikolakaki; Michel Goedert; Eva-Maria Mandelkow; Qing-Sheng Gao; Athena Andreadis; Stefan Stamm
Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors.
Molecular and cellular neurosciences 2001;18(1):80-90.
2001: Michel Goedert
Alpha-synuclein and neurodegenerative diseases.
Nature reviews. Neuroscience 2001;2(7):492-501.
2001: Michel Goedert
The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases.
Current opinion in genetics & development 2001;11(3):343-51.
2001: Yvonne L Woods; Philip Cohen; Walter Becker; Ross Jakes; Michel Goedert; Xuemin Wang; Christopher G Proud
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase.
The Biochemical journal 2001;355(Pt 3):609-15.
2001: Michel Goedert
Parkinson's disease and other alpha-synucleinopathies.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2001;39(4):308-12.
2001: Michel Goedert; Maria Grazia Spillantini; Louise C Serpell; John Berriman; MJ Smith; Ross Jakes; R Anthony Crowther
From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1406):213-27.
2001: Michel Goedert; Ross Jakes; R Anthony Crowther; M Grazia Spillantini
Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy as α-Synucleinopathies.
Methods in molecular medicine 2001;62():33-59.
2001: Virginia M-Y Lee; Michel Goedert; John Q Trojanowski
Neurodegenerative tauopathies.
Annual review of neuroscience 2001;24():1121-59.
2001: Michel Goedert; Maria Grazia Spillantini
Tau gene mutations and neurodegeneration.
Biochemical Society symposium 2001;(67):59-71.
2001: Jürgen Götz; Markus Tolnay; R Barmettler; Alessandra Ferrari; Kurt Bürki; Michel Goedert; Alphonse Probst; Roger M Nitsch
Human tau transgenic mice. Towards an animal model for neuro- and glialfibrillary lesion formation.
Advances in experimental medicine and biology 2001;487():71-83.
2001: Maria Grazia Spillantini; Michel Goedert
Tau gene mutations and tau pathology in frontotemporal dementia and parkinsonism linked to chromosome 17.
Advances in experimental medicine and biology 2001;487():21-37.
2000: Maria Grazia Spillantini; H Yoshida; C Rizzini; P L Lantos; N Khan; Martin N Rossor; Michel Goedert; Joanne Brown
A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies.
Annals of neurology 2000;48(6):939-43.
2000: Yvonne Fleming; Christopher G Armstrong; Nick Morrice; A Paterson; Michel Goedert; Philip Cohen
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.
The Biochemical journal 2000;352 Pt 1():145-54.
2000: MJ Smith; R Anthony Crowther; Michel Goedert
The natural osmolyte trimethylamine N-oxide (TMAO) restores the ability of mutant tau to promote microtubule assembly.
FEBS letters 2000;484(3):265-70.
2000: C Rizzini; Michel Goedert; John R Hodges; M J Smith; Ross Jakes; R Hills; John H Xuereb; R Anthony Crowther; Maria Grazia Spillantini
Tau gene mutation K257T causes a tauopathy similar to Pick's disease.
Journal of neuropathology and experimental neurology 2000;59(11):990-1001.
2000: Michel Goedert; Sivapong Satumtira; Ross Jakes; MJ Smith; Craig Kamibayashi; Charles L White; Estelle Sontag
Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations.
Journal of neurochemistry 2000;75(5):2155-62.
2000: R Anthony Crowther; Susan E Daniel; Michel Goedert
Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain.
Neuroscience letters 2000;292(2):128-30.
2000: Michel Goedert; Maria Grazia Spillantini
Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.
Biochimica et biophysica acta 2000;1502(1):110-21.
2000: R Anthony Crowther; Michel Goedert
Abnormal tau-containing filaments in neurodegenerative diseases.
Journal of structural biology 2000;130(2-3):271-9.
2000: Alphonse Probst; Jürgen Götz; Karl-Heinz Wiederhold; Markus Tolnay; C Mistl; Anne-Lise Jaton; M Hong; T Ishihara; Virginia M-Y Lee; John Q Trojanowski; Ross Jakes; R Anthony Crowther; Maria Grazia Spillantini; Kurt Bürki; Michel Goedert
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein.
Acta neuropathologica 2000;99(5):469-81.
2000: Maria Grazia Spillantini; Michel Goedert
Tau mutations in familial frontotemporal dementia.
Brain : a journal of neurology 2000;123 ( Pt 5)():857-9.
2000: Louise C Serpell; John Berriman; Ross Jakes; Michel Goedert; R Anthony Crowther
Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4897-902.
2000: karen duff; H Knight; Lorenzo M Refolo; S Sanders; X Yu; M Picciano; Brian Malester; Michael Hutton; J Adamson; Michel Goedert; K Burki; Peter Davies
Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes.
Neurobiology of disease 2000;7(2):87-98.
2000: Minoru Yasuda; J Takamatsu; Ian D'Souza; R A Crowther; Toshio Kawamata; M Hasegawa; Hiroshi Hasegawa; Maria Grazia Spillantini; Satoshi Tanimukai; Parvoneh Poorkaj-Navas; test testing; G Varani; Takeshi Iwatsubo; Michel Goedert; D G Schellenberg; Chikako Tanaka
A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto)
Annals of neurology 2000;47(4):422-9.
2000: Maria Grazia Spillantini; J C Van Swieten; Michel Goedert
Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17).
Neurogenetics 2000;2(4):193-205.
2000: Benoit I Giasson; Ross Jakes; Michel Goedert; John E Duda; Susan Leight; John Q Trojanowski; Virginia M-Y Lee
A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease.
Journal of neuroscience research 2000;59(4):528-33.
2000: test testing; Maria Grazia Spillantini; Michel Goedert; Gabriele Varani
Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.
Nucleic acids research 2000;28(3):710-9.
2000: Michel Goedert; Bernardino Ghetti; Maria Grazia Spillantini
Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurogenerative process.
Annals of the New York Academy of Sciences 2000;920():74-83.
2000: Bernardino Ghetti; Jill R Murrell; P Zolo; Maria Grazia Spillantini; Michel Goedert
Progress in hereditary tauopathies: a mutation in the Tau gene (G389R) causes a Pick disease-like syndrome.
Annals of the New York Academy of Sciences 2000;920():52-62.
2000: Maria Grazia Spillantini; Michel Goedert
The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.
Annals of the New York Academy of Sciences 2000;920():16-27.
2000: Jürgen Götz; R Barmettler; Alessandra Ferrari; Michel Goedert; Alphonse Probst; Roger M Nitsch
In vivo analysis of wild-type and FTDP-17 tau transgenic mice.
Annals of the New York Academy of Sciences 2000;920():126-33.
1999: Jill R Murrell; Maria Grazia Spillantini; P Zolo; Mario Guazzelli; M J Smith; M Hasegawa; F Redi; R Anthony Crowther; Pietro Pietrini; Bernardino Ghetti; Michel Goedert
Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits.
Journal of neuropathology and experimental neurology 1999;58(12):1207-26.
1999: M Craxton; Michel Goedert
Alternative splicing of synaptotagmins involving transmembrane exon skipping.
FEBS letters 1999;460(3):417-22.
1999: Michel Goedert; Aaron Klug
Tau protein and the paired helical filament of Alzheimer's disease.
Brain research bulletin 1999;50(5-6):469-70.
1999: AG Börsch-Haubold; Farideh Ghomashchi; S Pasquet; Michel Goedert; Philip Cohen; M H Gelb; Steve P Watson
Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways.
European journal of biochemistry / FEBS 1999;265(1):195-203.
1999: Gareth M Thomas; Sheelagh Frame; Michel Goedert; I Nathke; P Polakis; Philip Cohen
A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin.
FEBS letters 1999;458(2):247-51.
1999: CA Hall-Jackson; PA Eyers; Philip Cohen; Michel Goedert; F T Boyle; N Hewitt; H Plant; P Hedge
Paradoxical activation of Raf by a novel Raf inhibitor.
Chemistry & biology 1999;6(8):559-68.
1999: test testing; M Hasegawa; Maria Grazia Spillantini; MJ Smith; Jill R Murrell; Bernardino Ghetti; Aaron Klug; Michel Goedert; Gabriele Varani
Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):8229-34.
1999: Ross Jakes; R Anthony Crowther; Virginia M-Y Lee; John Q Trojanowski; Takeshi Iwatsubo; Michel Goedert
Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein.
Neuroscience letters 1999;269(1):13-6.
1999: Michel Goedert
Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1386):1101-18.
1999: Michel Goedert
Alzheimer's disease. Pinning down phosphorylated tau.
Nature 1999;399(6738):739-40.
1999: Maria Grazia Spillantini; M Tolnay; S Love; Michel Goedert
Microtubule-associated protein tau, heparan sulphate and alpha-synuclein in several neurodegenerative diseases with dementia.
Acta neuropathologica 1999;97(6):585-94.
1999: Orso Bugiani; Jill R Murrell; Giorgio Giaccone; M Hasegawa; G Ghigo; Massimo Tabaton; Michela Morbin; Alberto Primavera; F Carella; Claudio Solaro; Marina Grisoli; Mario Savoiardo; Maria Grazia Spillantini; Fabrizio Tagliavini; Michel Goedert; Bernardino Ghetti
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.
Journal of neuropathology and experimental neurology 1999;58(6):667-77.
1999: PA Eyers; Paul van den IJssel; Roy A Quinlan; Michel Goedert; Philip Cohen
Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580.
FEBS letters 1999;451(2):191-6.
1999: Michel Goedert; Ross Jakes; R Anthony Crowther
Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments.
FEBS letters 1999;450(3):306-11.
1999: M Hasegawa; Ana Cuenda; Maria Grazia Spillantini; Gareth M Thomas; Valérie Buée-Scherrer; Philip Cohen; Michel Goedert
Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition.
The Journal of biological chemistry 1999;274(18):12626-31.
1999: Suzanne S Mirra; Jill R Murrell; Marla Gearing; Maria Grazia Spillantini; Michel Goedert; R Anthony Crowther; Allan Levey; R Jones; J Green; J M Shoffner; Bruce H Wainer; M L Schmidt; John Q Trojanowski; Bernardino Ghetti
Tau pathology in a family with dementia and a P301L mutation in tau.
Journal of neuropathology and experimental neurology 1999;58(4):335-45.
1999: Michel Goedert; Maria Grazia Spillantini; R A Crowther; S G Chen; Piero Parchi; Massimo Tabaton; D J Lanska; William R Markesbery; Kirk Wilhelmsen; dennis dickson; R B Petersen; P Gambetti
Tau gene mutation in familial progressive subcortical gliosis.
Nature medicine 1999;5(4):454-7.
1999: CA Hall-Jackson; Michel Goedert; P Hedge; Philip Cohen
Effect of SB 203580 on the activity of c-Raf in vitro and in vivo.
Oncogene 1999;18(12):2047-54.
1999: Patrizia Rizzu; John C van Swieten; Marijke Joosse; M Hasegawa; M Stevens; Aad Tibben; Martinus F Niermeijer; M Hillebrand; Rivka Ravid; Ben A Oostra; Michel Goedert; C.M. Duijn; Peter Heutink
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands.
American journal of human genetics 1999;64(2):414-21.
1999: M Hasegawa; MJ Smith; M Iijima; Takeshi Tabira; Michel Goedert
FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10.
FEBS letters 1999;443(2):93-6.
1999: Michel Goedert; M Hasegawa
The tauopathies: toward an experimental animal model.
The American journal of pathology 1999;154(1):1-6.
1998: S Lawler; Yvonne Fleming; Michel Goedert; Philip Cohen
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro.
Current biology : CB 1998;8(25):1387-90.
1998: Michel Goedert; Maria Grazia Spillantini
Lewy body diseases and multiple system atrophy as alpha-synucleinopathies.
Molecular psychiatry 1998;3(6):462-5.
1998: Michel Goedert; R Anthony Crowther; Maria Grazia Spillantini
Tau mutations cause frontotemporal dementias.
Neuron 1998;21(5):955-8.
1998: M Hasegawa; MJ Smith; Michel Goedert
Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly.
FEBS letters 1998;437(3):207-10.
1998: R Anthony Crowther; Ross Jakes; Maria Grazia Spillantini; Michel Goedert
Synthetic filaments assembled from C-terminally truncated alpha-synuclein.
FEBS letters 1998;436(3):309-12.
1998: Poul Henning Jensen; Morten S Nielsen; R Jakes; C G Dotti; Michel Goedert
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.
The Journal of biological chemistry 1998;273(41):26292-4.
1998: John Q Trojanowski; Michel Goedert; Takeshi Iwatsubo; Virginia M-Y Lee
Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia.
Cell death and differentiation 1998;5(10):832-7.
1998: Michel Goedert; Maria Grazia Spillantini; S W Davies
Filamentous nerve cell inclusions in neurodegenerative diseases.
Current opinion in neurobiology 1998;8(5):619-32.
1998: Maria Grazia Spillantini; Michel Goedert
Tau protein pathology in neurodegenerative diseases.
Trends in neurosciences 1998;21(10):428-33.
1998: Michel Goedert; Ross Jakes; R Anthony Crowther; M Hasegawa; M J Smith; Maria Grazia Spillantini
Intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases.
Biochemical Society transactions 1998;26(3):463-71.
1998: Maria Grazia Spillantini; R Anthony Crowther; Ross Jakes; Nigel J Cairns; P L Lantos; Michel Goedert
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
Neuroscience letters 1998;251(3):205-8.
1998: Philip Cohen; Michel Goedert
Engineering protein kinases with distinct nucleotide specificities and inhibitor sensitivities by mutation of a single amino acid.
Chemistry & biology 1998;5(7):R161-4.
1998: Maria Grazia Spillantini; Jill R Murrell; Michel Goedert; Martin R Farlow; Aaron Klug; Bernardino Ghetti
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7737-41.
1998: PA Eyers; M Craxton; Nick Morrice; Philip Cohen; Michel Goedert
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution.
Chemistry & biology 1998;5(6):321-8.
1998: Maria Grazia Spillantini; R Anthony Crowther; Ross Jakes; M Hasegawa; Michel Goedert
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6469-73.
1998: Z QI; X Zhu; Michel Goedert; Donald J Fujita; Jerry H Wang
Effect of heparin on phosphorylation site specificity of neuronal Cdc2-like kinase.
FEBS letters 1998;423(2):227-30.
1998: Michel Goedert
Neurofibrillary pathology of Alzheimer's disease and other tauopathies.
Progress in brain research 1998;117():287-306.
1997: M Hasegawa; R Anthony Crowther; Ross Jakes; Michel Goedert
Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation.
The Journal of biological chemistry 1997;272(52):33118-24.
1997: Ana Cuenda; Michel Goedert; Molly Craxton; Ross Jakes; Philip Cohen
Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6).
Biochemical Society transactions 1997;25(4):S569.
1997: Jill R Murrell; D Koller; T Foroud; Michel Goedert; Maria Grazia Spillantini; H J Edenberg; Martin R Farlow; Bernardino Ghetti
Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17.
American journal of human genetics 1997;61(5):1131-8.
1997: S Lawler; Ana Cuenda; Michel Goedert; Philip Cohen
SKK4, a novel activator of stress-activated protein kinase-1 (SAPK1/JNK).
FEBS letters 1997;414(1):153-8.
1997: Maria Grazia Spillantini; M L Schmidt; Virginia M-Y Lee; John Q Trojanowski; R Jakes; Michel Goedert
Alpha-synuclein in Lewy bodies.
Nature 1997;388(6645):839-40.
1997: Nicolas Sergeant; Jean-Philippe David; Michel Goedert; R Jakes; Patrick Vermersch; Luc BUEE; Didier Lefranc; Annick Wattez; André Delacourte
Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications.
Journal of neurochemistry 1997;69(2):834-44.
1997: Michel Goedert
Familial Parkinson's disease. The awakening of alpha-synuclein.
Nature 1997;388(6639):232-3.
1997: Michel Goedert; Ana Cuenda; Molly Craxton; Ross Jakes; Philip Cohen
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.
The EMBO journal 1997;16(12):3563-71.
1997: Michel Goedert; M Hasegawa; Ross Jakes; S Lawler; Ana Cuenda; Philip Cohen
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases.
FEBS letters 1997;409(1):57-62.
1997: N Chevallier; J Jiracek; B Vincent; C P Baur; Maria Grazia Spillantini; Michel Goedert; Vincent Dive; Frédéric Checler
Examination of the role of endopeptidase 3.4.24.15 in A beta secretion by human transfected cells.
British journal of pharmacology 1997;121(3):556-62.
1997: M Craxton; A Olsen; Michel Goedert
Human synaptotagmin V (SYT5): sequence, genomic structure, and chromosomal location.
Genomics 1997;42(1):165-9.
1997: Michel Goedert; J Hasegawa; Molly Craxton; M A Leversha; SM Clegg
Assignment of the human stress-activated protein kinase-3 gene (SAPK3) to chromosome 22q13.3 by fluorescence in situ hybridization.
Genomics 1997;41(3):501-2.
1997: Markus Tolnay; Maria Grazia Spillantini; Michel Goedert; J Ulrich; D Langui; Alphonse Probst
Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons.
Acta neuropathologica 1997;93(5):477-84.
1997: Maria Grazia Spillantini; Michel Goedert; R Anthony Crowther; Jill R Murrell; Martin R Farlow; Bernardino Ghetti
Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4113-8.
1997: N Chevallier; Jean Vizzavona; Philippe Marambaud; C P Baur; Maria Grazia Spillantini; Pierre Fulcrand; Jean Martinez; Michel Goedert; J P Vincent; Frédéric Checler
Cathepsin D displays in vitro beta-secretase-like specificity.
Brain research 1997;750(1-2):11-9.
1997: Ana Cuenda; Philip Cohen; Valérie Buée-Scherrer; Michel Goedert
Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38).
The EMBO journal 1997;16(2):295-305.
1996: Alphonse Probst; Markus Tolnay; D Langui; Michel Goedert; Maria Grazia Spillantini
Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment.
Acta neuropathologica 1996;92(6):588-96.
1996: Michel Goedert; C P Baur; J Ahringer; R Jakes; M Hasegawa; Maria Grazia Spillantini; M J Smith; F Hill
PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans.
Journal of cell science 1996;109 ( Pt 11)():2661-72.
1996: Michel Goedert; Ross Jakes; Maria Grazia Spillantini; M Hasegawa; M J Smith; R Anthony Crowther
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans.
Nature 1996;383(6600):550-3.
1996: Maria Grazia Spillantini; R Anthony Crowther; Michel Goedert
Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles.
Acta neuropathologica 1996;92(1):42-8.
1996: V Buée-Scherrer; O Condamines; C Mourton-Gilles; R Jakes; Michel Goedert; B Pau; André Delacourte
AD2, a phosphorylation-dependent monoclonal antibody directed against tau proteins found in Alzheimer's disease.
Brain research. Molecular brain research 1996;39(1-2):79-88.
1996: J M Litersky; Gail Johnson; R Jakes; Michel Goedert; Michael K Lee; Peter Seubert
Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356.
The Biochemical journal 1996;316 ( Pt 2)():655-60.
1996: M Hasegawa; Ross Jakes; R Anthony Crowther; Virginia M-Y Lee; Yasuo Ihara; Michel Goedert
Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against tau protein.
FEBS letters 1996;384(1):25-30.
1996: S Mertens; Molly Craxton; Michel Goedert
SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases.
FEBS letters 1996;383(3):273-6.
1996: K Andrä; Dorothee Abramowski; M Duke; Alphonse Probst; Karl-Heinz Wiederhold; K Bürki; Michel Goedert; Bernd Sommer; Matthias Staufenbiel
Expression of APP in transgenic mice: a comparison of neuron-specific promoters.
Neurobiology of aging 1996;17(2):183-90.
1996: Michel Goedert; S Marsh; N Carter
Localization of the human kinesin light chain gene (KNS2) to chromosome 14q32.3 by fluorescence in situ hybridization.
Genomics 1996;32(1):173-5.
1996: Bernardino Ghetti; Pedro Piccardo; Maria Grazia Spillantini; Y Ichimiya; M Porro; F Perini; T Kitamoto; J Tateishi; C Seiler; Blas Frangione; Orso Bugiani; Giorgio Giaccone; F Prelli; Michel Goedert; Stephen R Dlouhy; Fabrizio Tagliavini
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):744-8.
1996: Allen D Roses; Gillian Einstein; John Gilbert; Michel Goedert; S H Han; D Huang; Christine M Hulette; Eliezer Masliah; Margaret Pericak-Vance; Ann M Saunders; Donald E Schmechel; Warren J Strittmatter; Karl H Weisgraber; P T Xi
Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism.
Annals of the New York Academy of Sciences 1996;777():146-57.
1996: Michel Goedert
Tau protein and the neurofibrillary pathology of Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;777():121-31.
1996: Michel Goedert; Maria Grazia Spillantini; M Hasegawa; Ross Jakes; R Anthony Crowther; Aaron Klug
Molecular dissection of the neurofibrillary lesions of Alzheimer's disease.
Cold Spring Harbor symposia on quantitative biology 1996;61():565-73.
1995: Michel Goedert; R Jakes; Z Qi; J H Wang; P Cohen
Protein phosphatase 2A is the major enzyme in brain that dephosphorylates tau protein phosphorylated by proline-directed protein kinases or cyclic AMP-dependent protein kinase.
Journal of neurochemistry 1995;65(6):2804-7.
1995: B R Sperber; Susan Leight; Michel Goedert; Virginia M-Y Lee
Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells.
Neuroscience letters 1995;197(2):149-53.
1995: Peter Seubert; M Mawal-Dewan; Robin Barbour; R Jakes; Michel Goedert; Gail Johnson; J M Litersky; Dale Schenk; I Lieberburg; John Q Trojanowski
Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.
The Journal of biological chemistry 1995;270(32):18917-22.
1995: David Y Huang; Karl H Weisgraber; Michel Goedert; Ann M Saunders; Allen D Roses; Warren J Strittmatter
ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation.
Neuroscience letters 1995;192(3):209-12.
1995: Maria Grazia Spillantini; A Divane; Michel Goedert
Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35.
Genomics 1995;27(2):379-81.
1995: Michel Goedert; Maria Grazia Spillantini; Ross Jakes; R Anthony Crowther; Eugeen Vanmechelen; A Probst; J Götz; K Bürki; Philip Cohen
Molecular dissection of the paired helical filament.
Neurobiology of aging 1995;16(3):325-34.
1995: Michel Goedert; Ross Jakes; Eugeen Vanmechelen
Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.
Neuroscience letters 1995;189(3):167-9.
1995: J Götz; A Probst; Maria Grazia Spillantini; T Schäfer; Ross Jakes; K Bürki; Michel Goedert
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.
The EMBO journal 1995;14(7):1304-13.
1995: Molly Craxton; Michel Goedert
Synaptotagmin V: a novel synaptotagmin isoform expressed in rat brain.
FEBS letters 1995;361(2-3):196-200.
1995: Michel Goedert
Molecular dissection of the neurofibrillary lesions of Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):403-9.
1995: Michel Goedert; Ross Jakes; Maria Grazia Spillantini; R Anthony Crowther; Philip Cohen; Eugeen Vanmechelen; A Probst; J Götz; K Bürki
Tau protein in Alzheimer's disease.
Biochemical Society transactions 1995;23(1):80-5.
1995: R Jakes; C R Harrington; Maria Grazia Spillantini; Michel Goedert; Aaron Klug
Characterisation of an antibody relevant to the neuropathology of Alzheimer disease.
Alzheimer disease and associated disorders 1995;9(1):47-51.
1994: Laszlo Otvos; L Feiner; E Lang; G I Szendrei; Michel Goedert; Virginia M-Y Lee
Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.
Journal of neuroscience research 1994;39(6):669-73.
1994: David Y Huang; Michel Goedert; R Jakes; Karl H Weisgraber; C C Garner; Ann M Saunders; Margaret Pericak-Vance; Donald E Schmechel; Allen D Roses; Warren J Strittmatter
Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease.
Neuroscience letters 1994;182(1):55-8.
1994: Warren J Strittmatter; Ann M Saunders; Michel Goedert; Karl H Weisgraber; L M Dong; R Jakes; David Y Huang; Margaret Pericak-Vance; Donald E Schmechel; Allen D Roses
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11183-6.
1994: Michel Goedert; Warren J Strittmatter; Allen D Roses
Alzheimer's disease. Risky apolipoprotein in brain.
Nature 1994;372(6501):45-6.
1994: James W Fawcett; G Mathews; E Housden; Michel Goedert; A Matus
Regenerating sciatic nerve axons contain the adult rather than the embryonic pattern of microtubule associated proteins.
Neuroscience 1994;61(4):789-804.
1994: Michel Goedert; Ross Jakes; R Anthony Crowther; Philip Cohen; Eugeen Vanmechelen; M Vandermeeren; Patrick Cras
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein.
The Biochemical journal 1994;301 ( Pt 3)():871-7.
1994: Ross Jakes; Maria Grazia Spillantini; Michel Goedert
Identification of two distinct synucleins from human brain.
FEBS letters 1994;345(1):27-32.
1994: Warren J Strittmatter; Karl H Weisgraber; Michel Goedert; Ann M Saunders; David Y Huang; Elizabeth H Corder; L M Dong; R Jakes; M J Alberts; John Gilbert
Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype.
Experimental neurology 1994;125(2):163-71; discussion 172-4.
1994: R Anthony Crowther; O F Olesen; M J Smith; R Jakes; Michel Goedert
Assembly of Alzheimer-like filaments from full-length tau protein.
FEBS letters 1994;337(2):135-8.
1993: M M Lo; A W Fieles; T E Norris; P G Dargis; C B Caputo; C W Scott; Virginia M-Y Lee; Michel Goedert
Human tau isoforms confer distinct morphological and functional properties to stably transfected fibroblasts.
Brain research. Molecular brain research 1993;20(3):209-20.
1993: Michel Goedert
Tau protein and the neurofibrillary pathology of Alzheimer's disease.
Trends in neurosciences 1993;16(11):460-5.
1993: J Robertson; T L Loviny; Michel Goedert; R Jakes; K J Murray; Brian H Anderton; Diane P Hanger
Phosphorylation of tau by cyclic-AMP-dependent protein kinase.
Dementia (Basel, Switzerland) 1993;4(5):256-63.
1993: Michel Goedert; Ross Jakes; R Anthony Crowther; J Six; Ursula Lübke; M Vandermeeren; Patrick Cras; John Q Trojanowski; Virginia M-Y Lee
The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5066-70.
1993: G T Bramblett; Michel Goedert; R Jakes; S E Merrick; John Q Trojanowski; Virginia M-Y Lee
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.
Neuron 1993;10(6):1089-99.
1993: J H Lee; Michel Goedert; William Hill; Virginia M-Y Lee; John Q Trojanowski
Tau proteins are abnormally expressed in olfactory epithelium of Alzheimer patients and developmentally regulated in human fetal spinal cord.
Experimental neurology 1993;121(1):93-105.
1992: Michel Goedert; E S Cohen; Ross Jakes; Philip Cohen
p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected].
FEBS letters 1992;312(1):95-9.
1992: Marie-Claude Potier; W L Kuo; A Dutriaux; Joe Gray; Michel Goedert
Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21.
Genomics 1992;14(2):481-3.
1992: R Anthony Crowther; O F Olesen; R Jakes; Michel Goedert
The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease.
FEBS letters 1992;309(2):199-202.
1992: N Gustke; B Steiner; Eva-Maria Mandelkow; Jacek Biernat; H E Meyer; Michel Goedert; Eckhard Mandelkow
The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs.
FEBS letters 1992;307(2):199-205.
1992: Jacek Biernat; Eva-Maria Mandelkow; C Schröter; B Lichtenberg-Kraag; B Steiner; B Berling; H Meyer; M Mercken; A Vandermeeren; Michel Goedert
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region.
The EMBO journal 1992;11(4):1593-7.
1992: Michel Goedert; Maria Grazia Spillantini; R Anthony Crowther
Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1983-7.
1992: Michel Goedert; Maria Grazia Spillantini; Nigel J Cairns; R Anthony Crowther
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms.
Neuron 1992;8(1):159-68.
1991: J Dingus; Bob Obar; J S Hyams; Michel Goedert; Richard B Vallee
Use of a heat-stable microtubule-associated protein class-specific antibody to investigate the mechanism of microtubule binding.
The Journal of biological chemistry 1991;266(28):18854-60.
1991: Michel Goedert; Sangram S Sisodia; Donald L Price
Neurofibrillary tangles and beta-amyloid deposits in Alzheimer's disease.
Current opinion in neurobiology 1991;1(3):441-7.
1991: Michel Goedert; Maria Grazia Spillantini; R Anthony Crowther
Tau proteins and neurofibrillary degeneration.
Brain pathology (Zurich, Switzerland) 1991;1(4):279-86.
1991: Michel Goedert; Maria Grazia Spillantini; Ross Jakes
Localization of the Alz-50 epitope in recombinant human microtubule-associated protein tau.
Neuroscience letters 1991;126(2):149-54.
1991: Michel Goedert; R A Crowther; C C Garner
Molecular characterization of microtubule-associated proteins tau and MAP2.
Trends in neurosciences 1991;14(5):193-9.
1991: A F Wright; Michel Goedert; N D Hastie
Familial Alzheimer's disease. Beta amyloid resurrected.
Nature 1991;349(6311):653-4.
1990: Michel Goedert; Ross Jakes
Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.
The EMBO journal 1990;9(13):4225-30.
1990: Stefan Kindler; B Schulz; Michel Goedert; Craig C Garner
Molecular structure of microtubule-associated protein 2b and 2c from rat brain.
The Journal of biological chemistry 1990;265(32):19679-84.
1990: Maria Grazia Spillantini; Michel Goedert; Ross Jakes; Aaron Klug
Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3947-51.
1990: Maria Grazia Spillantini; Michel Goedert; Ross Jakes; Aaron Klug
Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3952-6.
1990: Michel Goedert; Maria Grazia Spillantini
Molecular neuropathology of Alzheimer's disease: in situ hybridization studies.
Cellular and molecular neurobiology 1990;10(1):159-74.
1990: M R Hanley; W T Cheung; Phillip T Hawkins; David R Poyner; H P Benton; L Blair; Trevor Jackson; Michel Goedert
The mas oncogene as a neural peptide receptor: expression, regulation and mechanism of action.
Ciba Foundation symposium 1990;150():23-38; discussion 38-46.
1989: Shelley J Allen; David Dawbarn; Maria Grazia Spillantini; Michel Goedert; Gordon K Wilcock; T H Moss; F M Semenenko
Distribution of beta-nerve growth factor receptors in the human basal forebrain.
The Journal of comparative neurology 1989;289(4):626-40.
1989: Maria Grazia Spillantini; Luigi Aloe; E Alleva; R De Simone; Michel Goedert; R Levi-Montalcini
Nerve growth factor mRNA and protein increase in hypothalamus in a mouse model of aggression.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8555-9.
1989: Maria Grazia Spillantini; S P Hunt; J Ulrich; Michel Goedert
Expression and cellular localization of amyloid beta-protein precursor transcripts in normal human brain and in Alzheimer's disease.
Brain research. Molecular brain research 1989;6(2-3):143-50.
1989: Michel Goedert; Maria Grazia Spillantini; R Jakes; D Rutherford; R Anthony Crowther
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease.
Neuron 1989;3(4):519-26.
1989: Michel Goedert; R Anthony Crowther
Amyloid plaques, neurofibrillary tangles and their relevance for the study of Alzheimer's disease.
Neurobiology of aging 1989;10(5):405-6; discussion 412-4.
1989: Michel Goedert; Maria Grazia Spillantini; M C Potier; J Ulrich; R Anthony Crowther
Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.
The EMBO journal 1989;8(2):393-9.
1989: Michel Goedert
Radioligand-binding assays for study of neurotensin receptors.
Methods in enzymology 1989;168():462-81.
1989: Michel Goedert; A Fine; D Dawbarn; Gordon K Wilcock; M V Chao
Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease.
Brain research. Molecular brain research 1989;5(1):1-7.
1989: T Crowther; Michel Goedert; C M Wischik
The repeat region of microtubule-associated protein tau forms part of the core of the paired helical filament of Alzheimer's disease.
Annals of medicine 1989;21(2):127-32.
1988: T R Jackson; L A Blair; J Marshall; Michel Goedert; M R Hanley
The mas oncogene encodes an angiotensin receptor.
Nature 1988;335(6189):437-40.
1988: Michel Goedert; CM Wischik; R Anthony Crowther; John E Walker; Aaron Klug
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(11):4051-5.
1988: J Rogers; Michel Goedert; P W Wilson
An extra sequence in the lambda EMBL3 polylinker.
Nucleic acids research 1988;16(4):1633.
1987: Michel Goedert
Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease.
The EMBO journal 1987;6(12):3627-32.
1987: Michel Goedert; Stephen P Hunt
The cellular localization of preprotachykinin A messenger RNA in the bovine nervous system.
Neuroscience 1987;22(3):983-92.
1987: S P Hunt; Michel Goedert
The cellular localization of mRNA in neurobiology.
Biochemical Society transactions 1987;15(1):133.
1986: Michel Goedert
Molecular cloning of the chicken nerve growth factor gene: mRNA distribution in developing and adult tissues.
Biochemical and biophysical research communications 1986;141(3):1116-22.
1986: Michel Goedert; A Fine; S P Hunt; A Ullrich
Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease.
Brain research 1986;387(1):85-92.
1985: Michel Goedert; S L Lightman; P W Mantyh; S P Hunt; P C Emson
Neurotensin-like immunoreactivity and neurotensin receptors in the rat hypothalamus and in the neurointermediate lobe of the pituitary gland.
Brain research 1985;358(1-2):59-69.
1985: P C Emson; P M Horsfield; Michel Goedert; Martin N Rossor; Christopher Hawkes
Neurotensin in human brain: regional distribution and effects of neurological illness.
Brain research 1985;347(2):239-44.
1985: Michel Goedert; W N Schwartz; B J Williams
The comparative distribution of [Lys8-Asn9]-neurotensin8-13-like immunoreactivity in chicken and rat tissues.
Brain research 1985;342(2):259-65.
1985: Michel Goedert; S D Iversen; P C Emson
The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system.
Brain research 1985;335(2):334-6.
1985: Michel Goedert; S P Hunt; P W Mantyh; P C Emson
The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum.
Brain research 1985;352(1):127-31.
1985: M Fitzgerald; P D Wall; Michel Goedert; P C Emson
Nerve growth factor counteracts the neurophysiological and neurochemical effects of chronic sciatic nerve section.
Brain research 1985;332(1):131-41.
1985: J C Hunter; Michel Goedert; R D Pinnock
Mammalian tachykinin-induced hydrolysis of inositol phospholipids in rat brain slices.
Biochemical and biophysical research communications 1985;127(2):616-22.
1985: J G Reeve; Michel Goedert; P C Emson; N M Bleehen
Neurotensin in human small cell lung carcinoma.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1985;99():175-6.
1984: Michel Goedert; R D Pinnock; C P Downes; P W Mantyh; P C Emson
Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices.
Brain research 1984;323(1):193-7.
1984: Michel Goedert; J C Hunter; M Ninkovic
Evidence for neurotensin as a non-adrenergic, non-cholinergic neurotransmitter in guinea pig ileum.
Nature 1984;311(5981):59-62.
1984: Michael J Bannon; Michel Goedert; B Williams
The possible relation of glutathione, melanin and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease.
Biochemical pharmacology 1984;33(17):2697-8.
1984: Michel Goedert; N Sturmey; B J Williams; P C Emson
The comparative distribution of xenopsin- and neurotensin-like immunoreactivity in Xenopus laevis and rat tissues.
Brain research 1984;308(2):273-80.
1984: Michel Goedert; J G Reeve; P C Emson; N M Bleehen
Neurotensin in human small cell lung carcinoma.
British journal of cancer 1984;50(2):179-83.
1984: P W Mantyh; R D Pinnock; C P Downes; Michel Goedert; S P Hunt
Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS.
Nature 1984;309(5971):795-7.
1984: Michel Goedert; K Pittaway; B J Williams; P C Emson
Specific binding of tritiated neurotensin to rat brain membranes: characterization and regional distribution.
Brain research 1984;304(1):71-81.
1984: Michael J Bannon; Michel Goedert
Changes in substance P concentrations after protein synthesis inhibition provide an index of substance P utilization.
Brain research 1984;301(1):184-6.
1984: Michel Goedert; P W Mantyh; S P Hunt; P C Emson
Localization of specific neurotensin binding sites in the rat adrenal gland.
Brain research 1984;299(2):389-92.
1984: Michel Goedert; S L Lightman; P C Emson
Neurotensin in the rat anterior pituitary gland: effects of endocrinological manipulations.
Brain research 1984;299(1):160-3.
1984: Michel Goedert; K Pittaway; P C Emson
Neurotensin receptors in the rat striatum: lesion studies.
Brain research 1984;299(1):164-8.
1984: P D Marley; S L Lightman; M L Forsling; K Todd; Michel Goedert; J F Rehfeld; P C Emson
Localization and actions of cholecystokinin in the rat pituitary neurointermediate lobe.
Endocrinology 1984;114(5):1902-11.
1984: P W Mantyh; Michel Goedert; S P Hunt
Autoradiographic visualization of receptor binding sites for substance P in the gastrointestinal tract of the guinea pig.
European journal of pharmacology 1984;100(1):133-4.
1984: Michel Goedert; U Otten; S P Hunt; A Bond; D Chapman; M Schlumpf; W Lichtensteiger
Biochemical and anatomical effects of antibodies against nerve growth factor on developing rat sensory ganglia.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(5):1580-4.
1984: Michel Goedert; P W Mantyh; P C Emson; S P Hunt
Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum.
Nature 1984;307(5951):543-6.
1983: Michael J Bannon; P J Elliott; J E Alpert; Michel Goedert; S D Iversen; L L Iversen
Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurones.
Nature 1983;306(5945):791-2.
1983: Michel Goedert; P W Mantyh; S P Hunt; P C Emson
Mosaic distribution of neurotensin-like immunoreactivity in the cat striatum.
Brain research 1983;274(1):176-9.
1983: Michel Goedert; P C Emson
The regional distribution of neurotensin-like immunoreactivity in central and peripheral tissues of the cat.
Brain research 1983;272(2):291-7.
1983: Michel Goedert; G P Reynolds; P C Emson
Neurotensin in the adrenal medulla.
Neuroscience letters 1983;35(2):155-60.
1983: J I Nagy; L L Iversen; Michel Goedert; D Chapman; S P Hunt
Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(2):399-406.
1982: Michel Goedert; J I Nagy; P C Emson
The origin of substance P in the rat submandibular gland and its major duct.
Brain research 1982;252(2):327-33.
1982: Michel Goedert; S L Lightman; J I Nagy; P D Marley; P C Emson
Neurotensin in the rat anterior pituitary gland.
Nature 1982;298(5870):163-5.
1982: P C Emson; Michel Goedert; P Horsfield; F Rioux; S St Pierre
The regional distribution and chromatographic characterisation of neurotensin-like immunoreactivity in the rat central nervous system.
Journal of neurochemistry 1982;38(4):992-9.
1982: N Mayer; F Lembeck; Michel Goedert; U Otten
Effects of antibodies against nerve growth factor on the postnatal development of substance P-containing sensory neurons.
Neuroscience letters 1982;29(1):47-52.
1982: P C Emson; Michel Goedert; B Williams; M Ninkovic; S P Hunt
Neurotensin: regional distribution, characterization, and inactivation.
Annals of the New York Academy of Sciences 1982;400():198-215.
1982: P C Emson; Michel Goedert; H Benton; S St-Pierre; F Rioux
The regional distribution and chromatographic characterization of neurotensin-like immunoreactivity in the rat.
Advances in biochemical psychopharmacology 1982;33():477-85.
1982: J I Nagy; Michel Goedert; S P Hunt; A Bond
The nature of the substance P-containing nerve fibres in taste papillae of the rat tongue.
Neuroscience 1982;7(12):3137-51.
1981: Michel Goedert; K Stoeckel; U Otten
Biological importance of the retrograde axonal transport of nerve growth factor in sensory neurons.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(9):5895-8.
1981: U Otten; Michel Goedert; J B Baumann; J Girard
Stimulation of the pituitary-adrenocortical axis and induction of tyrosine hydroxylase by nerve growth factor are not dependent on mouse submaxillary gland isorenin.
Brain research 1981;217(1):207-11.
1981: Michel Goedert; U Otten; H Metz
Endogenous opioid peptides.
Bulletin de la Société des sciences médicales du Grand-Duché de Luxembourg 1981;118(1):7-17.
1980: Michel Goedert; U Otten; T Schäfer; M Schwab; H Thoenen
Immunosympathectomy: lack of evidence for a complement-mediated cytotoxic mechanism.
Brain research 1980;201(2):399-409.
1980: U Otten; Michel Goedert; N Mayer; F Lembeck
Requirement of nerve growth factor for development of substance P-containing sensory neurones.
Nature 1980;287(5778):158-9.
1980: Michel Goedert; U Otten; K Suda; P U Heitz; G A Stalder; J P Obrecht; P Holzach; M Allgöwer
Dopamine, norepinephrine and serotonin production by an intestinal carcinoid tumor.
Cancer 1980;45(1):104-7.
1979: U Otten; Michel Goedert; M Schwab; J Thibault
Immunization of adult rats against 2.5 S NGF: effects on the peripheral sympathetic nervous system.
Brain research 1979;176(1):79-90.
1978: Michel Goedert; U Otten; H Thoenen
Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia.
Brain research 1978;148(1):264-8.
1978: Michel Goedert; U Otten; H Thoenen
Biochemical effects of nerve growth factor and its antibody on the vas defferens and the adrenal medulla.
Neuroscience letters 1978;8(1):71-6.
1978: Michel Goedert
Nerve growth factor: its growing importance for neurobiology and medicine.
Bulletin de la Société des sciences médicales du Grand-Duché de Luxembourg 1978;115(2):69-74.
1977: Michel Goedert; F R Bühler
Nerve-growth-factor antibodies in idiopathic orthostatic hypotension?
The New England journal of medicine 1977;297(6):336-7.
1975: Michel Goedert; F Achaeffer; P Neuberg
Letter: White cells and uric acid in alcoholism.
Lancet 1975;1(7897):52.