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Stephen Goff

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
10
Cong, Feng
10
Luban, Jeremy
9
Tanese, Naoko
9
Tsang, Stephen
9
Gouras, Peter
6
Hatziioannou, Theodora
6
Gao, Guangxia
6
Kalpana, Ganjam
6
Bacharach, Eran
6
Blain, Stacy W.
6
Telesnitsky, Alice
6
Roth, Monica
5
Orlova, Marianna
5
Prasad, Vinayaka
5
Tachedjian, Gilda

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Publications

TOP 3
Valente Susana T; Gilmartin Greg M; Venkatarama Krishnan; Arriagada Gloria; Goff Stephen P
HIV-1 mRNA 3' end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8.
Liberatore Rachel A; Goff Stephen P; Nunes Irene
NF-kappaB activity is constitutively elevated in c-Abl null fibroblasts.
Wolf Daniel; Goff Stephen P
Embryonic stem cells use ZFP809 to silence retroviral DNAs.

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All Publications

2009: Valente Susana T; Gilmartin Greg M; Venkatarama Krishnan; Arriagada Gloria; Goff Stephen P
HIV-1 mRNA 3' end processing is distinctively regulated by eIF3f, CDK11, and splice factor 9G8.
Molecular cell 2009;36(2):279-89.
2009: Liberatore Rachel A; Goff Stephen P; Nunes Irene
NF-kappaB activity is constitutively elevated in c-Abl null fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17823-8.
2009: Wolf Daniel; Goff Stephen P
Embryonic stem cells use ZFP809 to silence retroviral DNAs.
Nature 2009;458(7242):1201-4.
2009: Liberatore Rachel A; Goff Stephen P
c-Abl-deficient mice exhibit reduced numbers of peritoneal B-1 cells and defects in BCR-induced B cell activation.
International immunology 2009;21(4):403-14.
2009: Valente Susana T; Gilmartin Greg M; Mott Christina; Falkard Brie; Goff Stephen P
Inhibition of HIV-1 replication by eIF3f.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4071-8.
2009: Valente Susana T; Goff Stephen P
Somatic cell genetic analyses to identify HIV-1 host restriction factors.
Methods in molecular biology (Clifton, N.J.) 2009;485():235-55.
2008: Goff Stephen P
Knockdown screens to knockout HIV-1.
Cell 2008;135(3):417-20.
2008: Wolf Daniel; Hug Kevin; Goff Stephen P
TRIM28 mediates primer binding site-targeted silencing of Lys1,2 tRNA-utilizing retroviruses in embryonic cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(34):12521-6.
2008: Haedicke Juliane; de Los Santos Kenia; Goff Stephen P; Naghavi Mojgan H
The Ezrin-radixin-moesin family member ezrin regulates stable microtubule formation and retroviral infection.
Journal of virology 2008;82(9):4665-70.
2008: Wolf Daniel; Cammas Florence; Losson Régine; Goff Stephen P
Primer binding site-dependent restriction of murine leukemia virus requires HP1 binding by TRIM28.
Journal of virology 2008;82(9):4675-9.
2008: Wolf Daniel; Goff Stephen P
Host restriction factors blocking retroviral replication.
Annual review of genetics 2008;42():143-63.
2008: Studamire Barbara; Goff Stephen P
Host proteins interacting with the Moloney murine leukemia virus integrase: multiple transcriptional regulators and chromatin binding factors.
Retrovirology 2008;5():48.
2007: Wolf Daniel; Goff Stephen P
TRIM28 mediates primer binding site-targeted silencing of murine leukemia virus in embryonic cells.
Cell 2007;131(1):46-57.
2007: Naghavi Mojgan H; Goff Stephen P
Retroviral proteins that interact with the host cell cytoskeleton.
Current opinion in immunology 2007;19(4):402-7.
2007: Goff Stephen P
Host factors exploited by retroviruses.
Nature reviews. Microbiology 2007;5(4):253-63.
2007: Bouamr Fadila; Houck-Loomis Brian R; De Los Santos Martha; Casaday Rebecca J; Johnson Marc C; Goff Stephen P
The C-terminal portion of the Hrs protein interacts with Tsg101 and interferes with human immunodeficiency virus type 1 Gag particle production.
Journal of virology 2007;81(6):2909-22.
2007: Tsang Stephen H; Woodruff Michael L; Jun Lin; Mahajan Vinit; Yamashita Clyde K; Pedersen Robert; Lin Chyuan-Sheng; Goff Stephen P; Rosenberg Thomas; Larsen Michael; Farber Debora B; Nusinowitz Steven
Transgenic mice carrying the H258N mutation in the gene encoding the beta-subunit of phosphodiesterase-6 (PDE6B) provide a model for human congenital stationary night blindness.
Human mutation 2007;28(3):243-54.
2007: Cang Yong; Zhang Jianxuan; Nicholas Sally A; Kim Arianna L; Zhou Pengbo; Goff Stephen P
DDB1 is essential for genomic stability in developing epidermis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2733-7.
2007: Naghavi Mojgan H; Valente Susana; Hatziioannou Theodora; de Los Santos Kenia; Wen Ying; Mott Christina; Gundersen Gregg G; Goff Stephen P
Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells.
The EMBO journal 2007;26(1):41-52.
2006: Cang Yong; Zhang Jianxuan; Nicholas Sally A; Bastien Jayson; Li Baojie; Zhou Pengbo; Goff Stephen P
Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells.
Cell 2006;127(5):929-40.
2006: Lim David; Gregorio G Glenn; Bingman Craig; Martinez-Hackert Erik; Hendrickson Wayne A; Goff Stephen P
Crystal structure of the moloney murine leukemia virus RNase H domain.
Journal of virology 2006;80(17):8379-89.
2006: Valente Susana T; Goff Stephen P
Inhibition of HIV-1 gene expression by a fragment of hnRNP U.
Molecular cell 2006;23(4):597-605.
2006: Leung Juliana; Yueh Andrew; Appah Frank S K; Yuan Bing; de los Santos Kenia; Goff Stephen P
Interaction of Moloney murine leukemia virus matrix protein with IQGAP.
The EMBO journal 2006;25(10):2155-66.
2006: Liu Shufeng; Goff Stephen P; Gao Guangxia
Gln(84) of moloney murine leukemia virus reverse transcriptase regulates the incorporation rates of ribonucleotides and deoxyribonucleotides.
FEBS letters 2006;580(5):1497-501.
2006: Yueh Andrew; Leung Juliana; Bhattacharyya Subarna; Perrone Lucy A; de los Santos Kenia; Pu Szy-Yuan; Goff Stephen P
Interaction of moloney murine leukemia virus capsid with Ubc9 and PIASy mediates SUMO-1 addition required early in infection.
Journal of virology 2006;80(1):342-52.
2005: Naghavi Mojgan H; Hatziioannou Theodora; Gao Guangxia; Goff Stephen P
Overexpression of fasciculation and elongation protein zeta-1 (FEZ1) induces a post-entry block to retroviruses in cultured cells.
Genes & development 2005;19(9):1105-15.
2005: Bouamr Fadila; Cornilescu Claudia C; Goff Stephen P; Tjandra Nico; Carter Carol A
Structural and dynamics studies of the D54A mutant of human T cell leukemia virus-1 capsid protein.
The Journal of biological chemistry 2005;280(8):6792-801.
2005: Tachedjian Gilda; Moore Katie L; Goff Stephen P; Sluis-Cremer Nicolas
Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation.
FEBS letters 2005;579(2):379-84.
2004: Goff Stephen P
Retrovirus restriction factors.
Molecular cell 2004;16(6):849-59.
2004: Guo Xuemin; Carroll John-William N; Macdonald Margaret R; Goff Stephen P; Gao Guangxia
The zinc finger antiviral protein directly binds to specific viral mRNAs through the CCCH zinc finger motifs.
Journal of virology 2004;78(23):12781-7.
2004: Evans Matthew J; Rice Charles M; Goff Stephen P
Genetic interactions between hepatitis C virus replicons.
Journal of virology 2004;78(21):12085-9.
2004: Doi Kentaro; Kong Jian; Hargitai Janos; Goff Stephen P; Gouras Peter
Transient immunosuppression stops rejection of virus-transduced enhanced green fluorescent protein in rabbit retina.
Journal of virology 2004;78(20):11327-33.
2004: Evans Matthew J; Rice Charles M; Goff Stephen P
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(35):13038-43.
2004: Li Baojie; Wang Xueying; Rasheed Naslin; Hu Yuanyu; Boast Sharon; Ishii Tetsuro; Nakayama Keiko; Nakayama Keiichi I; Goff Stephen P
Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta.
Genes & development 2004;18(15):1824-37.
2004: Evans Matthew J; Bacharach Eran; Goff Stephen P
RNA sequences in the Moloney murine leukemia virus genome bound by the Gag precursor protein in the yeast three-hybrid system.
Journal of virology 2004;78(14):7677-84.
2004: Moradpour Darius; Evans Matthew J; Gosert Rainer; Yuan Zhenghong; Blum Hubert E; Goff Stephen P; Lindenbach Brett D; Rice Charles M
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes.
Journal of virology 2004;78(14):7400-9.
2004: Goff Stephen P
Genetic reprogramming by retroviruses: enhanced suppression of translational termination.
Cell cycle (Georgetown, Tex.) 2004;3(2):123-5.
2004: Goff Stephen P
Genetic control of retrovirus susceptibility in mammalian cells.
Annual review of genetics 2004;38():61-85.
2004: Gao Guangxia; Goff Stephen P
Isolation of suppressor genes that restore retrovirus susceptibility to a virus-resistant cell line.
Retrovirology 2004;1():30.
2003: Bouamr Fadila; Melillo Jessica A; Wang Margaret Q; Nagashima Kunio; de Los Santos Martha; Rein Alan; Goff Stephen P
PPPYVEPTAP motif is the late domain of human T-cell leukemia virus type 1 Gag and mediates its functional interaction with cellular proteins Nedd4 and Tsg101 [corrected].
Journal of virology 2003;77(22):11882-95.
2003: Bick Matthew J; Carroll John-William N; Gao Guangxia; Goff Stephen P; Rice Charles M; MacDonald Margaret R
Expression of the zinc-finger antiviral protein inhibits alphavirus replication.
Journal of virology 2003;77(21):11555-62.
2003: Orlova Marianna; Yueh Andrew; Leung Juliana; Goff Stephen P
Reverse transcriptase of Moloney murine leukemia virus binds to eukaryotic release factor 1 to modulate suppression of translational termination.
Cell 2003;115(3):319-31.
2003: Towers Greg J; Hatziioannou Theodora; Cowan Simone; Goff Stephen P; Luban Jeremy; Bieniasz Paul D
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors.
Nature medicine 2003;9(9):1138-43.
2003: Tachedjian Gilda; Goff Stephen P
The effect of NNRTIs on HIV reverse transcriptase dimerization.
Current opinion in investigational drugs (London, England : 2000) 2003;4(8):966-73.
2003: Goff Stephen P
Death by deamination: a novel host restriction system for HIV-1.
Cell 2003;114(3):281-3.
2003: Nunes Irene; Tovmasian Lucy T; Silva Robert M; Burke Robert E; Goff Stephen P
Pitx3 is required for development of substantia nigra dopaminergic neurons.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4245-50.
2003: Wang Margaret Q; Goff Stephen P
Defects in virion production caused by mutations affecting the C-terminal portion of the Moloney murine leukemia virus capsid protein.
Journal of virology 2003;77(5):3339-44.
2003: Fan Pang-Dian; Cong Feng; Goff Stephen P
Homo- and hetero-oligomerization of the c-Abl kinase and Abelson-interactor-1.
Cancer research 2003;63(4):873-7.
2003: Tachedjian Gilda; Aronson Hans-Erik G; de los Santos Martha; Seehra Jas; McCoy John M; Goff Stephen P
Role of residues in the tryptophan repeat motif for HIV-1 reverse transcriptase dimerization.
Journal of molecular biology 2003;326(2):381-96.
2003: Hatziioannou Theodora; Cowan Simone; Goff Stephen P; Bieniasz Paul D; Towers Greg J
Restriction of multiple divergent retroviruses by Lv1 and Ref1.
The EMBO journal 2003;22(3):385-94.
2003: Yueh Andrew; Goff Stephen P
Phosphorylated serine residues and an arginine-rich domain of the moloney murine leukemia virus p12 protein are required for early events of viral infection.
Journal of virology 2003;77(3):1820-9.
2003: Wang Margaret Q; Kim Wankee; Gao Guangxia; Torrey Ted A; Morse Herbert C; De Camilli Pietro; Goff Stephen P
Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production.
Journal of biology 2003;3(1):4.
2002: Yuan Bing; Fassati Ariberto; Yueh Andrew; Goff Stephen P
Characterization of Moloney murine leukemia virus p12 mutants blocked during early events of infection.
Journal of virology 2002;76(21):10801-10.
2002: Gao Guangxia; Guo Xuemin; Goff Stephen P
Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein.
Science (New York, N.Y.) 2002;297(5587):1703-6.
2002: Cong Feng; Tang Jean; Hwang Byung Joon; Vuong Bao Q; Chu Gilbert; Goff Stephen P
Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase.
The Journal of biological chemistry 2002;277(38):34870-8.
2002: Lim David; Orlova Marianna; Goff Stephen P
Mutations of the RNase H C helix of the Moloney murine leukemia virus reverse transcriptase reveal defects in polypurine tract recognition.
Journal of virology 2002;76(16):8360-73.
2002: Li Baojie; Cong Feng; Tan Choon Ping; Wang Sherry X; Goff Stephen P
Aph2, a protein with a zf-DHHC motif, interacts with c-Abl and has pro-apoptotic activity.
The Journal of biological chemistry 2002;277(32):28870-6.
2002: Zhang Yi-Jun; Hatziioannou Theodora; Zang Trinity; Braaten Douglas; Luban Jeremy; Goff Stephen P; Bieniasz Paul D
Envelope-dependent, cyclophilin-independent effects of glycosaminoglycans on human immunodeficiency virus type 1 attachment and infection.
Journal of virology 2002;76(12):6332-43.
2002: Li Baojie; Ishii Tetsuro; Tan Choon Ping; Soh Jae-Won; Goff Stephen P
Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C.
The Journal of biological chemistry 2002;277(14):12418-22.
2002: Tsang Stephen H; Yamashita Clyde K; Lee Won Ho; Lin Chyuan Sheng; Goff Stephen P; Gouras Peter; Farber Debora B
The positive role of the carboxyl terminus of the gamma subunit of retinal cGMP-phosphodiesterase in maintaining phosphodiesterase activity in vivo.
Vision research 2002;42(4):439-45.
2001: Goff S P
Intracellular trafficking of retroviral genomes during the early phase of infection: viral exploitation of cellular pathways.
The journal of gene medicine 2001;3(6):517-28.
2001: Hatziioannou T; Goff S P
Infection of nondividing cells by Rous sarcoma virus.
Journal of virology 2001;75(19):9526-31.
2001: Ikeguchi A; Yang H Y; Gao G; Goff S P
Inhibition of v-Abl transformation in 3T3 cells overexpressing different forms of the Abelson interactor protein Abi-1.
Oncogene 2001;20(36):4926-34.
2001: Tachedjian G; Orlova M; Sarafianos S G; Arnold E; Goff S P
Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7188-93.
2001: Nunes I; Higgins R D; Zanetta L; Shamamian P; Goff S P
c-abl is required for the development of hyperoxia-induced retinopathy.
The Journal of experimental medicine 2001;193(12):1383-91.
2001: Fassati A; Goff S P
Characterization of intracellular reverse transcription complexes of human immunodeficiency virus type 1.
Journal of virology 2001;75(8):3626-35.
2001: Gonsky J; Bacharach E; Goff S P
Identification of residues of the Moloney murine leukemia virus nucleocapsid critical for viral DNA synthesis in vivo.
Journal of virology 2001;75(6):2616-26.
2001: Tsang S H; Yamashita C K; Doi K; Salchow D J; Bouvier N; Mendelsohn M; Gouras P; Farber D B; Goff S P
In vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84.
The Biochemical journal 2001;353(Pt 3):467-74.
2000: Cong F; Spencer S; Côté J F; Wu Y; Tremblay M L; Lasky L A; Goff S P
Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation.
Molecular cell 2000;6(6):1413-23.
2000: Bacharach E; Gonsky J; Alin K; Orlova M; Goff S P
The carboxy-terminal fragment of nucleolin interacts with the nucleocapsid domain of retroviral gag proteins and inhibits virion assembly.
Journal of virology 2000;74(23):11027-39.
2000: Fan P D; Goff S P
Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases.
Molecular and cellular biology 2000;20(20):7591-601.
2000: Lai C C; Gouras P; Doi K; Tsang S H; Goff S P; Ashton P
Local immunosuppression prolongs survival of RPE xenografts labeled by retroviral gene transfer.
Investigative ophthalmology & visual science 2000;41(10):3134-41.
2000: Yuan B; Campbell S; Bacharach E; Rein A; Goff S P
Infectivity of Moloney murine leukemia virus defective in late assembly events is restored by late assembly domains of other retroviruses.
Journal of virology 2000;74(16):7250-60.
2000: Tachedjian G; Aronson H E; Goff S P
Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6334-9.
2000: Bacharach E; Gonsky J; Lim D; Goff S P
Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5' plus-strand DNA ends in vivo.
Journal of virology 2000;74(10):4755-64.
2000: Li B; Boast S; de los Santos K; Schieren I; Quiroz M; Teitelbaum S L; Tondravi M M; Goff S P
Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation.
Nature genetics 2000;24(3):304-8.
2000: Yano H; Cong F; Birge R B; Goff S P; Chao M V
Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor.
Journal of neuroscience research 2000;59(3):356-64.
2000: Zou X; Cong F; Coutts M; Cattoretti G; Goff S P; Calame K
p53 deficiency increases transformation by v-Abl and rescues the ability of a C-terminally truncated v-Abl mutant to induce pre-B lymphoma in vivo.
Molecular and cellular biology 2000;20(2):628-33.
1999: Cong F; Zou X; Hinrichs K; Calame K; Goff S P
Inhibition of v-Abl transformation by p53 and p19ARF.
Oncogene 1999;18(54):7731-9.
1999: Salchow D J; Gouras P; Doi K; Goff S P; Schwinger E; Tsang S H
A point mutation (W70A) in the rod PDE-gamma gene desensitizing and delaying murine rod photoreceptors.
Investigative ophthalmology & visual science 1999;40(13):3262-7.
1999: Cong F; Yuan B; Goff S P
Characterization of a novel member of the DOK family that binds and modulates Abl signaling.
Molecular and cellular biology 1999;19(12):8314-25.
1999: Tang Y; Winkler U; Freed E O; Torrey T A; Kim W; Li H; Goff S P; Morse H C
Cellular motor protein KIF-4 associates with retroviral Gag.
Journal of virology 1999;73(12):10508-13.
1999: Cong F; Goff S P
c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13819-24.
1999: Fassati A; Goff S P
Characterization of intracellular reverse transcription complexes of Moloney murine leukemia virus.
Journal of virology 1999;73(11):8919-25.
1999: Dorsch M; Danial N N; Rothman P B; Goff S P
A thrombopoietin receptor mutant deficient in Jak-STAT activation mediates proliferation but not differentiation in UT-7 cells.
Blood 1999;94(8):2676-85.
1999: Yuan B; Li X; Goff S P
Mutations altering the moloney murine leukemia virus p12 Gag protein affect virion production and early events of the virus life cycle.
The EMBO journal 1999;18(17):4700-10.
1999: Lai C C; Gouras P; Doi K; Lu F; Kjeldbye H; Goff S P; Pawliuk R; Leboulch P; Tsang S H
Tracking RPE transplants labeled by retroviral gene transfer with green fluorescent protein.
Investigative ophthalmology & visual science 1999;40(9):2141-6.
1999: Gao G; Goff S P
Somatic cell mutants resistant to retrovirus replication: intracellular blocks during the early stages of infection.
Molecular biology of the cell 1999;10(6):1705-17.
1999: Chen G; Yuan S S; Liu W; Xu Y; Trujillo K; Song B; Cong F; Goff S P; Wu Y; Arlinghaus R; Baltimore D; Gasser P J; Park M S; Sung P; Lee E Y
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl.
The Journal of biological chemistry 1999;274(18):12748-52.
1998: Danial N N; Losman J A; Lu T; Yip N; Krishnan K; Krolewski J; Goff S P; Wang J Y; Rothman P B
Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation.
Molecular and cellular biology 1998;18(11):6795-804.
1998: Tsang S H; Burns M E; Calvert P D; Gouras P; Baylor D A; Goff S P; Arshavsky V Y
Role for the target enzyme in deactivation of photoreceptor G protein in vivo.
Science (New York, N.Y.) 1998;282(5386):117-21.
1998: Bacharach E; Goff S P
Binding of the human immunodeficiency virus type 1 Gag protein to the viral RNA encapsidation signal in the yeast three-hybrid system.
Journal of virology 1998;72(8):6944-9.
1998: Gao G; Goff S P
Replication defect of moloney murine leukemia virus with a mutant reverse transcriptase that can incorporate ribonucleotides and deoxyribonucleotides.
Journal of virology 1998;72(7):5905-11.
1998: Fisher J; Goff S P
Mutational analysis of stem-loops in the RNA packaging signal of the Moloney murine leukemia virus.
Virology 1998;244(1):133-45.
1997: Dorsch M; Fan P D; Danial N N; Rothman P B; Goff S P
The thrombopoietin receptor can mediate proliferation without activation of the Jak-STAT pathway.
The Journal of experimental medicine 1997;186(12):1947-55.
1997: Bellosta P; Zhang Q; Goff S P; Basilico C
Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulation.
Oncogene 1997;15(20):2387-97.
1997: Li X; Yuan B; Goff S P
Genetic analysis of interactions between Gag proteins of Rous sarcoma virus.
Journal of virology 1997;71(7):5624-30.
1997: Tsang S H; Chen J; Kjeldbye H; Li W S; Simon M I; Gouras P; Goff S P
Retarding photoreceptor degeneration in Pdegtm1/Pdegtml mice by an apoptosis suppressor gene.
Investigative ophthalmology & visual science 1997;38(5):943-50.
1997: Gao G; Orlova M; Georgiadis M M; Hendrickson W A; Goff S P
Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):407-11.
1996: Reicin A S; Ohagen A; Yin L; Hoglund S; Goff S P
The role of Gag in human immunodeficiency virus type 1 virion morphogenesis and early steps of the viral life cycle.
Journal of virology 1996;70(12):8645-52.
1996: Dorsch M; Goff S P
Increased sensitivity to apoptotic stimuli in c-abl-deficient progenitor B-cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13131-6.
1996: Zhang Q K; Boast S; de los Santos K; Begemann M; Goff S P
Transforming activity of retroviral genomes encoding Gag-Axl fusion proteins.
Journal of virology 1996;70(11):8089-97.
1996: Wang W; Côté J; Xue Y; Zhou S; Khavari P A; Biggar S R; Muchardt C; Kalpana G V; Goff S P; Yaniv M; Workman J L; Crabtree G R
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
The EMBO journal 1996;15(19):5370-82.
1996: Goff S P
Operating under a Gag order: a block against incoming virus by the Fv1 gene.
Cell 1996;86(5):691-3.
1996: Hardin J D; Boast S; Schwartzberg P L; Lee G; Alt F W; Stall A M; Goff S P
Abnormal peripheral lymphocyte function in c-abl mutant mice.
Cellular immunology 1996;172(1):100-7.
1996: Alin K; Goff S P
Amino acid substitutions in the CA protein of Moloney murine leukemia virus that block early events in infection.
Virology 1996;222(2):339-51.
1996: Hardin J D; Boast S; Mendelsohn M; de los Santos K; Goff S P
Transgenes encoding both type I and type IV c-abl proteins rescue the lethality of c-abl mutant mice.
Oncogene 1996;12(12):2669-77.
1996: Tsang S H; Gouras P; Yamashita C K; Kjeldbye H; Fisher J; Farber D B; Goff S P
Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase.
Science (New York, N.Y.) 1996;272(5264):1026-9.
1996: Strober B E; Dunaief J L; Guha; Goff S P
Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins.
Molecular and cellular biology 1996;16(4):1576-83.
1996: Granowitz C; Berkowitz R D; Goff S P
Mutations affecting the cytoplasmic domain of the Moloney murine leukemia virus envelope protein: rapid reversion during replication.
Virus research 1996;41(1):25-42.
1996: Alin K; Goff S P
Mutational analysis of interactions between the Gag precursor proteins of murine leukemia viruses.
Virology 1996;216(2):418-24.
1996: Li X; McDermott B; Yuan B; Goff S P
Homomeric interactions between transmembrane proteins of Moloney murine leukemia virus.
Journal of virology 1996;70(2):1266-70.
1996: Blain S W; Goff S P
Differential effects of Moloney murine leukemia virus reverse transcriptase mutations on RNase H activity in Mg2+ and Mn2+.
The Journal of biological chemistry 1996;271(3):1448-54.
1996: Fallows D A; Goff S P
Hepadnaviruses: current models of RNA encapsidation and reverse transcription.
Advances in virus research 1996;46():165-94.
1995: Shi Y; Alin K; Goff S P
Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity.
Genes & development 1995;9(21):2583-97.
1995: Hardin J D; Boast S; Schwartzberg P L; Lee G; Alt F W; Stall A M; Goff S P
Bone marrow B lymphocyte development in c-abl-deficient mice.
Cellular immunology 1995;165(1):44-54.
1995: Berkowitz R D; Ohagen A; Höglund S; Goff S P
Retroviral nucleocapsid domains mediate the specific recognition of genomic viral RNAs by chimeric Gag polyproteins during RNA packaging in vivo.
Journal of virology 1995;69(10):6445-56.
1995: Berkowitz R D; Hammarskjöld M L; Helga-Maria C; Rekosh D; Goff S P
5' regions of HIV-1 RNAs are not sufficient for encapsidation: implications for the HIV-1 packaging signal.
Virology 1995;212(2):718-23.
1995: Georgiadis M M; Jessen S M; Ogata C M; Telesnitsky A; Goff S P; Hendrickson W A
Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase.
Structure (London, England : 1993) 1995;3(9):879-92.
1995: Dunaief J L; Kwun R C; Bhardwaj N; Lopez R; Gouras P; Goff S P
Retroviral gene transfer into retinal pigment epithelial cells followed by transplantation into rat retina.
Human gene therapy 1995;6(9):1225-9.
1995: Dorsch M; Fan P D; Bogenberger J; Goff S P
TPO and IL-3 induce overlapping but distinct protein tyrosine phosphorylation in a myeloid precursor cell line.
Biochemical and biophysical research communications 1995;214(2):424-31.
1995: Blain S W; Hendrickson W A; Goff S P
Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity.
Journal of virology 1995;69(8):5113-6.
1995: Dingwall A K; Beek S J; McCallum C M; Tamkun J W; Kalpana G V; Goff S P; Scott M P
The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex.
Molecular biology of the cell 1995;6(7):777-91.
1995: Blain S W; Goff S P
Effects on DNA synthesis and translocation caused by mutations in the RNase H domain of Moloney murine leukemia virus reverse transcriptase.
Journal of virology 1995;69(7):4440-52.
1995: Fallows D A; Goff S P
Mutations in the epsilon sequences of human hepatitis B virus affect both RNA encapsidation and reverse transcription.
Journal of virology 1995;69(5):3067-73.
1995: Wong K K; Hardin J D; Boast S; Cooper C L; Merrell K T; Doyle T G; Goff S P; Calame K L
A role for c-Abl in c-myc regulation.
Oncogene 1995;10(4):705-11.
1995: Reicin A S; Paik S; Berkowitz R D; Luban J; Lowy I; Goff S P
Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity.
Journal of virology 1995;69(2):642-50.
1995: Telesnitsky A; Blain S; Goff S P
Assays for retroviral reverse transcriptase.
Methods in enzymology 1995;262():347-62.
1994: Kalpana G V; Marmon S; Wang W; Crabtree G R; Goff S P
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5.
Science (New York, N.Y.) 1994;266(5193):2002-6.
1994: Granowitz C; Goff S P
Substitution mutations affecting a small region of the Moloney murine leukemia virus MA gag protein block assembly and release of virion particles.
Virology 1994;205(1):336-44.
1994: Murphy J E; Goff S P
Forced integration of Moloney murine leukemia virus DNA with a mutant integration site occurs through recombination with VL30 DNA.
Virology 1994;204(1):458-61.
1994: Dunaief J L; Strober B E; Guha S; Khavari P A; Alin K; Luban J; Begemann M; Crabtree G R; Goff S P
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest.
Cell 1994;79(1):119-30.
1994: Franke E K; Yuan H E; Bossolt K L; Goff S P; Luban J
Specificity and sequence requirements for interactions between various retroviral Gag proteins.
Journal of virology 1994;68(8):5300-5.
1994: Berkowitz R D; Goff S P
Analysis of binding elements in the human immunodeficiency virus type 1 genomic RNA and nucleocapsid protein.
Virology 1994;202(1):233-46.
1994: Luban J; Goff S P
Mutational analysis of cis-acting packaging signals in human immunodeficiency virus type 1 RNA.
Journal of virology 1994;68(6):3784-93.
1994: Lowy I; Caruso M; Goff S P; Klatzmann D
Cellular thymidine kinase activity is required for the inhibition of HIV-1 replication by AZT in lymphocytes.
Virology 1994;200(1):271-5.
1993: Shrivastava A; Saleque S; Kalpana G V; Artandi S; Goff S P; Calame K
Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc.
Science (New York, N.Y.) 1993;262(5141):1889-92.
1993: Berkowitz R D; Luban J; Goff S P
Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays.
Journal of virology 1993;67(12):7190-200.
1993: Kalpana G V; Goff S P
Genetic analysis of homomeric interactions of human immunodeficiency virus type 1 integrase using the yeast two-hybrid system.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10593-7.
1993: Blain S W; Goff S P
Nuclease activities of Moloney murine leukemia virus reverse transcriptase. Mutants with altered substrate specificities.
The Journal of biological chemistry 1993;268(31):23585-92.
1993: Telesnitsky A; Goff S P
Two defective forms of reverse transcriptase can complement to restore retroviral infectivity.
The EMBO journal 1993;12(11):4433-8.
1993: Berkowitz R D; Goff S P
Point mutations in Moloney murine leukemia virus envelope protein: effects on infectivity, virion association, and superinfection resistance.
Virology 1993;196(2):748-57.
1993: Hevezi P; Alin K; Goff S P
Transforming activity and tissue tropism of hybrid retroviral genomes containing portions of the v-abl and v-src oncogenes.
Oncogene 1993;8(9):2413-23.
1993: Murphy J E; De Los Santos T; Goff S P
Mutational analysis of the sequences at the termini of the Moloney murine leukemia virus DNA required for integration.
Virology 1993;195(2):432-40.
1993: Luban J; Bossolt K L; Franke E K; Kalpana G V; Goff S P
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B.
Cell 1993;73(6):1067-78.
1993: Luban J; Lee C; Goff S P
Effect of linker insertion mutations in the human immunodeficiency virus type 1 gag gene on activation of viral protease expressed in bacteria.
Journal of virology 1993;67(6):3630-4.
1993: Schwartzberg P L; Roth M J; Tanese N; Goff S P
Analysis of a temperature-sensitive mutation affecting the integration protein of Moloney murine leukemia virus.
Virology 1993;192(2):673-8.
1993: Telesnitsky A; Goff S P
RNase H domain mutations affect the interaction between Moloney murine leukemia virus reverse transcriptase and its primer-template.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1276-80.
1992: Charron J; Malynn B A; Fisher P; Stewart V; Jeannotte L; Goff S P; Robertson E J; Alt F W
Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.
Genes & development 1992;6(12A):2248-57.
1992: Hevezi P; Alin K; Rees-Jones R; Goff S P
Bone marrow-transforming activity of linker insertion mutants of Abelson murine leukemia virus.
Oncogene 1992;7(11):2323-8.
1992: Felsenstein K M; Goff S P
Mutational analysis of the gag-pol junction of Moloney murine leukemia virus: requirements for expression of the gag-pol fusion protein.
Journal of virology 1992;66(11):6601-8.
1992: Luban J; Alin K B; Bossolt K L; Humaran T; Goff S P
Genetic assay for multimerization of retroviral gag polyproteins.
Journal of virology 1992;66(8):5157-60.
1992: Murphy J E; Goff S P
A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo.
Journal of virology 1992;66(8):5092-5.
1992: Telesnitsky A; Blain S W; Goff S P
Defects in Moloney murine leukemia virus replication caused by a reverse transcriptase mutation modeled on the structure of Escherichia coli RNase H.
Journal of virology 1992;66(2):615-22.
1992: Goff S P
Genetics of retroviral integration.
Annual review of genetics 1992;26():527-44.
1991: Hevezi P; Goff S P
Generation of recombinant murine retroviral genomes containing the v-src oncogene: isolation of a virus inducing hemangiosarcomas in the brain.
Journal of virology 1991;65(10):5333-41.
1991: Granowitz C; Colicelli J; Goff S P
Analysis of mutations in the envelope gene of Moloney murine leukemia virus: separation of infectivity from superinfection resistance.
Virology 1991;183(2):545-54.
1991: Tanese N; Telesnitsky A; Goff S P
Abortive reverse transcription by mutants of Moloney murine leukemia virus deficient in the reverse transcriptase-associated RNase H function.
Journal of virology 1991;65(8):4387-97.
1991: Schwartzberg P L; Stall A M; Hardin J D; Bowdish K S; Humaran T; Boast S; Harbison M L; Robertson E J; Goff S P
Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations.
Cell 1991;65(7):1165-75.
1991: Luban J; Goff S P
Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein.
Journal of virology 1991;65(6):3203-12.
1990: Prasad V R; Myrick K; Haseltine W; Goff S P
Expression of enzymatically active reverse transcriptase of simian immunodeficiency virus in bacteria: sensitivity to nucleotide analogue inhibitors.
Virology 1990;179(2):896-900.
1990: Roth M J; Schwartzberg P; Tanese N; Goff S P
Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting.
Journal of virology 1990;64(10):4709-17.
1990: Goff S P
Integration of retroviral DNA into the genome of the infected cell.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1990;2(6):172-8.
1990: Schwartzberg P L; Robertson E J; Goff S P
Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):3210-4.
1990: Charron J; Malynn B A; Robertson E J; Goff S P; Alt F W
High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination.
Molecular and cellular biology 1990;10(4):1799-804.
1990: Martinelli S C; Goff S P
Rapid reversion of a deletion mutation in Moloney murine leukemia virus by recombination with a closely related endogenous provirus.
Virology 1990;174(1):135-44.
1990: Glass D J; Rees-Jones R W; Goff S P
Isolation and characterization of flat revertant cell lines from A-MuLV-transformed fibroblasts.
Oncogene research 1990;5(3):175-85.
1990: Prasad V R; Goff S P
Structure-function studies of HIV reverse transcriptase.
Annals of the New York Academy of Sciences 1990;616():11-21.
1989: Schwartzberg P L; Goff S P; Robertson E J
Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells.
Science (New York, N.Y.) 1989;246(4931):799-803.
1989: Prasad V R; Goff S P
A novel in situ colony screening method to detect human immunodeficiency virus reverse transcriptase activity expressed in bacteria. Isolation of pseudorevertants of reverse transcriptase mutants.
The Journal of biological chemistry 1989;264(28):16689-93.
1989: Roth M J; Schwartzberg P L; Goff S P
Structure of the termini of DNA intermediates in the integration of retroviral DNA: dependence on IN function and terminal DNA sequence.
Cell 1989;58(1):47-54.
1989: Tanese N; Roth M; Epstein H; Goff S P
An insertion mutation in the pol gene of Moloney murine leukemia virus results in temperature-sensitive pol maturation and viral replication.
Virology 1989;170(2):378-84.
1989: Lobel L I; Murphy J E; Goff S P
The palindromic LTR-LTR junction of Moloney murine leukemia virus is not an efficient substrate for proviral integration.
Journal of virology 1989;63(6):2629-37.
1989: Prasad V R; Goff S P
Linker insertion mutagenesis of the human immunodeficiency virus reverse transcriptase expressed in bacteria: definition of the minimal polymerase domain.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3104-8.
1989: Méric C; Goff S P
Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein.
Journal of virology 1989;63(4):1558-68.
1989: Murphy J E; Goff S P
Construction and analysis of deletion mutations in the U5 region of Moloney murine leukemia virus: effects on RNA packaging and reverse transcription.
Journal of virology 1989;63(1):319-27.
1989: Rees-Jones R W; Goldfarb M; Goff S P
Abelson murine leukemia virus induces platelet-derived growth factor-independent fibroblast growth: correlation with kinase activity and dissociation from full morphologic transformation.
Molecular and cellular biology 1989;9(1):278-87.
1988: Roth M J; Tanese N; Goff S P
Gene product of Moloney murine leukemia virus required for proviral integration is a DNA-binding protein.
Journal of molecular biology 1988;203(1):131-9.
1988: Tanese N; Prasad V R; Goff S P
Structural requirements for bacterial expression of stable, enzymatically active fusion proteins containing the human immunodeficiency virus reverse transcriptase.
DNA (Mary Ann Liebert, Inc.) 1988;7(6):407-16.
1988: Felsenstein K M; Goff S P
Expression of the gag-pol fusion protein of Moloney murine leukemia virus without gag protein does not induce virion formation or proteolytic processing.
Journal of virology 1988;62(6):2179-82.
1988: Rees-Jones R W; Goff S P
Insertional mutagenesis of the Abelson murine leukemia virus genome: identification of mutants with altered kinase activity and defective transformation ability.
Journal of virology 1988;62(3):978-86.
1988: Tanese N; Goff S P
Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(6):1777-81.
1988: Colicelli J; Goff S P
Isolation of an integrated provirus of Moloney murine leukemia virus with long terminal repeats in inverted orientation: integration utilizing two U3 sequences.
Journal of virology 1988;62(2):633-6.
1988: Colicelli J; Goff S P
Sequence and spacing requirements of a retrovirus integration site.
Journal of molecular biology 1988;199(1):47-59.
1988: Markowitz D G; Goff S P; Bank A
Safe and efficient ecotropic and amphotropic packaging lines for use in gene transfer experiments.
Transactions of the Association of American Physicians 1988;101():212-8.
1987: Colicelli J; Goff S P
Identification of endogenous retroviral sequences as potential donors for recombinational repair of mutant retroviruses: positions of crossover points.
Virology 1987;160(2):518-22.
1986: Tanese N; Roth M J; Goff S P
Analysis of retroviral pol gene products with antisera raised against fusion proteins produced in Escherichia coli.
Journal of virology 1986;59(2):328-40.
1985: Roth M J; Tanese N; Goff S P
Purification and characterization of murine retroviral reverse transcriptase expressed in Escherichia coli.
The Journal of biological chemistry 1985;260(16):9326-35.

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