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William Goins

Research Profile

Chemicals & Drugs

Living Beings

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Gene Transfer Techniques

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Genome, Viral

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Publications

TOP 3
Hitoshi Yokoyama; William C de Groat; Joseph C Glorioso; William F Goins; James R Goss; David M Krisky; Osamu Nishizawa; Tomohiko Oguchi; Darren Wolfe; Naoki Yoshimura
Effects of herpes simplex virus vector-mediated enkephalin gene therapy on bladder overactivity and nociception.
Yasuhito Funahashi; Joseph C Glorioso; William F Goins; James R Goss; Momokazu Gotoh; Tomohiko Oguchi; Pradeep Tyagi; Naoki Yoshimura
Herpes simplex virus vector mediated gene therapy of tumor necrosis factor-α blockade for bladder overactivity and nociception in rats.
William F Goins; David M Krisky; James B Wechuck; Darren Wolfe; Shaohua Huang; Joseph C Glorioso
Generation of replication-competent and -defective HSV vectors.

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All Publications

2013: Hitoshi Yokoyama; William C de Groat; Joseph C Glorioso; William F Goins; James R Goss; David M Krisky; Osamu Nishizawa; Tomohiko Oguchi; Darren Wolfe; Naoki Yoshimura
Effects of herpes simplex virus vector-mediated enkephalin gene therapy on bladder overactivity and nociception.
Human gene therapy 2013;24(2):170-80.
2013: Yasuhito Funahashi; Joseph C Glorioso; William F Goins; James R Goss; Momokazu Gotoh; Tomohiko Oguchi; Pradeep Tyagi; Naoki Yoshimura
Herpes simplex virus vector mediated gene therapy of tumor necrosis factor-α blockade for bladder overactivity and nociception in rats.
The Journal of urology 2013;189(1):366-73.
2011: William F Goins; David M Krisky; James B Wechuck; Darren Wolfe; Shaohua Huang; Joseph C Glorioso
Generation of replication-competent and -defective HSV vectors.
Cold Spring Harbor protocols 2011;2011(5):pdb.prot5615.
2011: James R Goss; Michael Cascio; William F Goins; Shaohua Huang; David M Krisky; Richard J Clarke; Jon W Johnson; Hitoshi Yokoyama; Naoki Yoshimura; Michael S Gold; Joseph C Glorioso
HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(3):500-6.
2010: Hiroaki Uchida; Janet Chan; William F Goins; Paola Grandi; Izumi Kumagai; Justus B Cohen; Joseph C Glorioso
A double mutation in glycoprotein gB compensates for ineffective gD-dependent initiation of herpes simplex virus type 1 infection.
Journal of virology 2010;84(23):12200-9.
2010: Minoru Miyazato; Kimio Sugaya; Seiichi Saito; Michael B Chancellor; William F Goins; James R Goss; william chesney de groat; Joseph C Glorioso; Naoki Yoshimura
Suppression of detrusor-sphincter dyssynergia by herpes simplex virus vector mediated gene delivery of glutamic acid decarboxylase in spinal cord injured rats.
The Journal of urology 2010;184(3):1204-10.
2010: Arthur R Frampton; Hiroaki Uchida; Jens von Einem; William F Goins; Paola Grandi; Justus B Cohen; Nikolaus Osterrieder; Joseph C Glorioso
Equine herpesvirus type 1 (EHV-1) utilizes microtubules, dynein, and ROCK1 to productively infect cells.
Veterinary microbiology 2010;141(1-2):12-21.
2009: William F Goins; James R Goss; Michael B Chancellor; william chesney de groat; Joseph C Glorioso; Naoki Yoshimura
Herpes simplex virus vector-mediated gene delivery for the treatment of lower urinary tract pain.
Gene therapy 2009;16(4):558-69.
2009: Hiroaki Uchida; Waris A Shah; Ali Ozuer; Arthur R Frampton; William F Goins; Paola Grandi; Justus B Cohen; Joseph C Glorioso
Generation of herpesvirus entry mediator (HVEM)-restricted herpes simplex virus type 1 mutant viruses: resistance of HVEM-expressing cells and identification of mutations that rescue nectin-1 recognition.
Journal of virology 2009;83(7):2951-61.
2009: Hitoshi Yokoyama; Katsumi Sasaki; Michael E Franks; William F Goins; James R Goss; william chesney de groat; Joseph C Glorioso; Michael B Chancellor; Naoki Yoshimura
Gene therapy for bladder overactivity and nociception with herpes simplex virus vectors expressing preproenkephalin.
Human gene therapy 2009;20(1):63-71.
2008: William F Goins; David M Krisky; James B Wechuck; Shaohua Huang; Joseph C Glorioso
Construction and production of recombinant herpes simplex virus vectors.
Methods in molecular biology (Clifton, N.J.) 2008;433():97-113.
2007: Arthur R Frampton; Donna B Stolz; Hiroaki Uchida; William F Goins; Justus B Cohen; Joseph C Glorioso
Equine herpesvirus 1 enters cells by two different pathways, and infection requires the activation of the cellular kinase ROCK1.
Journal of virology 2007;81(20):10879-89.
2007: R Kato; Darren Wolfe; C H Coyle; Shaohua Huang; James B Wechuck; William F Goins; David M Krisky; T Tsukamoto; Joel B Nelson; Joseph C Glorioso; Michael B Chancellor; Naoki Yoshimura
Herpes simplex virus vector-mediated delivery of glial cell line-derived neurotrophic factor rescues erectile dysfunction following cavernous nerve injury.
Gene therapy 2007;14(18):1344-52.
2007: James R Goss; William F Goins; Joseph C Glorioso
Gene therapy applications for the treatment of neuropathic pain.
Expert review of neurotherapeutics 2007;7(5):487-506.
2007: Marianna Tsvitov; Arthur R Frampton; Waris A Shah; Steven K Wendell; Ali Ozuer; Zoher Kapacee; William F Goins; Justus B Cohen; Joseph C Glorioso
Characterization of soluble glycoprotein D-mediated herpes simplex virus type 1 infection.
Virology 2007;360(2):477-91.
2006: Chang-Sook Hong; William F Goins; James R Goss; Edward A Burton; Joseph C Glorioso
Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer's disease-related amyloid-beta peptide in vivo.
Gene therapy 2006;13(14):1068-79.
2006: Heechung Kwon; Qing Bai; Hyun-Jung Baek; Kelly Felmet; Edward A Burton; William F Goins; Justus B Cohen; Joseph C Glorioso
Soluble V domain of Nectin-1/HveC enables entry of herpes simplex virus type 1 (HSV-1) into HSV-resistant cells by binding to viral glycoprotein D.
Journal of virology 2006;80(1):138-48.
2005: Arthur R Frampton; William F Goins; K Nakano; Edward A Burton; Joseph C Glorioso
HSV trafficking and development of gene therapy vectors with applications in the nervous system.
Gene therapy 2005;12(11):891-901.
2005: Nelson E Bennett; Jang H Kim; Darren P Wolfe; Katsumi Sasaki; Naoki Yoshimura; William F Goins; Shaohua Huang; Joel B Nelson; william chesney de groat; Joseph C Glorioso; Michael B Chancellor
Improvement in erectile dysfunction after neurotrophic factor gene therapy in diabetic rats.
The Journal of urology 2005;173(5):1820-4.
2005: Kenji Nakano; Ryutaro Asano; Kouhei Tsumoto; Heechung Kwon; William F Goins; Izumi Kumagai; Justus B Cohen; Joseph C Glorioso
Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(4):617-26.
2005: Arthur R Frampton; William F Goins; Justus B Cohen; Jens von Einem; Nikolaus Osterrieder; Dennis J O'Callaghan; Joseph C Glorioso
Equine herpesvirus 1 utilizes a novel herpesvirus entry receptor.
Journal of virology 2005;79(5):3169-73.
2005: J Fradette; Darren Wolfe; William F Goins; Shaohua Huang; R M Flanigan; Joseph C Glorioso
HSV vector-mediated transduction and GDNF secretion from adipose cells.
Gene therapy 2005;12(1):48-58.
2004: Katsumi Sasaki; Michael B Chancellor; William F Goins; Michael W Phelan; Joseph C Glorioso; william chesney de groat; Naoki Yoshimura
Gene therapy using replication-defective herpes simplex virus vectors expressing nerve growth factor in a rat model of diabetic cystopathy.
Diabetes 2004;53(10):2723-30.
2004: Canping Jiang; James B Wechuck; William F Goins; David M Krisky; Darren Wolfe; Mohammad M Ataai; Joseph C Glorioso
Immobilized cobalt affinity chromatography provides a novel, efficient method for herpes simplex virus type 1 gene vector purification.
Journal of virology 2004;78(17):8994-9006.
2004: Darren Wolfe; James B Wechuck; David M Krisky; Julie P Goff; William F Goins; Ali Ozuer; Michael E Epperly; Joel S Greenberger; David J Fink; Joseph C Glorioso
Delivery of herpes simplex virus-based vectors to stem cells.
Methods in molecular biology (Clifton, N.J.) 2004;246():339-52.
2004: Ajay Niranjan; Darren Wolfe; Wendy Fellows; William F Goins; Joseph C Glorioso; Douglas Kondziolka; L Dade Lunsford
Gene transfer to glial tumors using herpes simplex virus.
Methods in molecular biology (Clifton, N.J.) 2004;246():323-37.
2004: William F Goins; Darren Wolfe; David M Krisky; Qing Bai; Edward A Burton; David J Fink; Joseph C Glorioso
Delivery using herpes simplex virus: an overview.
Methods in molecular biology (Clifton, N.J.) 2004;246():257-99.
2003: Shuanglin Hao; Marina Mata; William F Goins; Joseph C Glorioso; David J Fink
Transgene-mediated enkephalin release enhances the effect of morphine and evades tolerance to produce a sustained antiallodynic effect in neuropathic pain.
Pain 2003;102(1-2):135-42.
2003: Edward A Burton; Shaohua Huang; William F Goins; Joseph C Glorioso
Use of the herpes simplex viral genome to construct gene therapy vectors.
Methods in molecular medicine 2003;76():1-31.
2002: James R Goss; Cara F Harley; Marina Mata; Mark E O'Malley; William F Goins; XiaoPing Hu; Joseph C Glorioso; David J Fink
Herpes vector-mediated expression of proenkephalin reduces bone cancer pain.
Annals of neurology 2002;52(5):662-5.
2002: Edward A Burton; Qing Bai; William F Goins; Joseph C Glorioso
Replication-defective genomic herpes simplex vectors: design and production.
Current opinion in biotechnology 2002;13(5):424-8.
2002: William F Goins; Pierfrancesco Marconi; David M Krisky; Darren Wolfe; Joseph C Glorioso; Ramesh Ramakrishnan; David J Fink
Construction of replication-defective herpes simplex virus vectors.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2002;Chapter 12():Unit 12.11.
2002: James B Wechuck; Ali Ozuer; William F Goins; Darren Wolfe; Thomas J Oligino; Joseph C Glorioso; Mohammad M Ataai
Effect of temperature, medium composition, and cell passage on production of herpes-based viral vectors.
Biotechnology and bioengineering 2002;79(1):112-9.
2002: James R Goss; William F Goins; David Lacomis; Marina Mata; Joseph C Glorioso; David J Fink
Herpes simplex-mediated gene transfer of nerve growth factor protects against peripheral neuropathy in streptozotocin-induced diabetes in the mouse.
Diabetes 2002;51(7):2227-32.
2002: Ali Ozuer; James B Wechuck; Brian A Russell; Darren Wolfe; William F Goins; Joseph C Glorioso; Mohammad M Ataai
Evaluation of infection parameters in the production of replication-defective HSV-1 viral vectors.
Biotechnology progress 2002;18(3):476-82.
2002: Ali Ozuer; James B Wechuck; William F Goins; Darren Wolfe; Joseph C Glorioso; Mohammad M Ataai
Effect of genetic background and culture conditions on the production of herpesvirus-based gene therapy vectors.
Biotechnology and bioengineering 2002;77(6):685-92.
2002: William F Goins; David M Krisky; Darren P Wolfe; David J Fink; Joseph C Glorioso
Development of replication-defective herpes simplex virus vectors.
Methods in molecular medicine 2002;69():481-507.
2001: Edward A Burton; Qing Bai; William F Goins; Joseph C Glorioso
Targeting gene expression using HSV vectors.
Advanced drug delivery reviews 2001;53(2):155-70.
2001: Naoki Yoshimura; Michael E Franks; Katsumi Sasaki; William F Goins; James Goss; Teruhiko Yokoyama; Matthew Fraser; Satoshi Seki; J Fink; Joseph C Glorioso; william chesney de groat; Michael B Chancellor
Gene therapy of bladder pain with herpes simplex virus (HSV) vectors expressing preproenkephalin (PPE).
Urology 2001;57(6 Suppl 1):116.
2001: William F Goins; Naoki Yoshimura; Michael W Phelan; Teruhiko Yokoyama; Matthew Fraser; H Ozawa; J R Bennett N; william chesney de groat; Joseph C Glorioso; Michael B Chancellor
Herpes simplex virus mediated nerve growth factor expression in bladder and afferent neurons: potential treatment for diabetic bladder dysfunction.
The Journal of urology 2001;165(5):1748-54.
2001: James R Goss; Marina Mata; William F Goins; H H Wu; Joseph C Glorioso; David J Fink
Antinociceptive effect of a genomic herpes simplex virus-based vector expressing human proenkephalin in rat dorsal root ganglion.
Gene therapy 2001;8(7):551-6.
2001: Edward A Burton; James B Wechuck; Steven K Wendell; William F Goins; David J Fink; Joseph C Glorioso
Multiple applications for replication-defective herpes simplex virus vectors.
Stem cells (Dayton, Ohio) 2001;19(5):358-77.
2001: Darren Wolfe; William F Goins; T J Kaplan; Saverio Capuano; J Fradette; M Murphey-Corb; Paul D Robbins; Justus B Cohen; Joseph C Glorioso
Herpesvirus-mediated systemic delivery of nerve growth factor.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(1):61-9.
2000: RJ Rouse; W Seifried; S K Mistry; William F Goins; Joseph C Glorioso
Herpes simplex virus-enhanced cationic lipid/DNA-mediated transfection.
BioTechniques 2000;29(4):810-4.
2000: James B Wechuck; William F Goins; Joseph C Glorioso; Mohammad M Ataai
Effect of protease inhibitors on yield of HSV-1-based viral vectors.
Biotechnology progress 2000;16(3):493-6.
2000: Dina Anderson; S Laquerre; K Ghosh; H P Ghosh; William F Goins; Justus B Cohen; Joseph C Glorioso
Pseudotyping of glycoprotein D-deficient herpes simplex virus type 1 with vesicular stomatitis virus glycoprotein G enables mutant virus attachment and entry.
Journal of virology 2000;74(5):2481-7.
2000: Pierfrancesco Marconi; Masakazu Tamura; Shusuke Moriuchi; David M Krisky; Ajay Niranjan; William F Goins; Justus B Cohen; Joseph C Glorioso
Connexin 43-enhanced suicide gene therapy using herpesviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(1):71-81.
1999: Darren Wolfe; William F Goins; M Yamada; Shusuke Moriuchi; David M Krisky; Thomas J Oligino; Pierfrancesco Marconi; David J Fink; Joseph C Glorioso
Engineering herpes simplex virus vectors for CNS applications.
Experimental neurology 1999;159(1):34-46.
1999: M R Alvira; William F Goins; Justus B Cohen; Joseph C Glorioso
Genetic studies exposing the splicing events involved in herpes simplex virus type 1 latency-associated transcript production during lytic and latent infection.
Journal of virology 1999;73(5):3866-76.
1999: William F Goins; K A Lee; James Cavalcoli; Mark E O'Malley; Steven T DeKosky; David J Fink; Joseph C Glorioso
Herpes simplex virus type 1 vector-mediated expression of nerve growth factor protects dorsal root ganglion neurons from peroxide toxicity.
Journal of virology 1999;73(1):519-32.
1998: David M Krisky; Darren Wolfe; William F Goins; Pierfrancesco Marconi; R Ramakrishnan; Marina Mata; RJ Rouse; David J Fink; Joseph C Glorioso
Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons.
Gene therapy 1998;5(12):1593-603.
1997: William F Goins; David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; R Ramakrishnan; PL Poliani; David J Fink; Joseph C Glorioso
Herpes simplex virus vectors for gene transfer to the nervous system.
Journal of neurovirology 1997;3 Suppl 1():S80-8.
1997: David J Fink; PL Poliani; Thomas J Oligino; David M Krisky; William F Goins; Joseph C Glorioso
Development of an HSV-based vector for the treatment of Parkinson's disease.
Experimental neurology 1997;144(1):103-21.
1997: Joseph C Glorioso; William F Goins; Martin C Schmidt; Thomas J Oligino; David M Krisky; Pierfrancesco Marconi; James Cavalcoli; R Ramakrishnan; PL Poliani; David J Fink
Engineering herpes simplex virus vectors for human gene therapy.
Advances in pharmacology (San Diego, Calif.) 1997;40():103-36.
1996: Pierfrancesco Marconi; David M Krisky; Thomas J Oligino; PL Poliani; R Ramakrishnan; William F Goins; David J Fink; Joseph C Glorioso
Replication-defective herpes simplex virus vectors for gene transfer in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11319-20.
1996: David J Fink; Neal A DeLuca; William F Goins; Joseph C Glorioso
Gene transfer to neurons using herpes simplex virus-based vectors.
Annual review of neuroscience 1996;19():265-87.
1995: X Chen; Martin C Schmidt; William F Goins; Joseph C Glorioso
Two herpes simplex virus type 1 latency-active promoters differ in their contributions to latency-associated transcript expression during lytic and latent infections.
Journal of virology 1995;69(12):7899-908.
1995: Joseph C Glorioso; M A Bender; William F Goins; David J Fink; Neal A DeLuca
HSV as a gene transfer vector for the nervous system.
Molecular biotechnology 1995;4(1):87-99.
1995: Johnny Huard; William F Goins; Joseph C Glorioso
Herpes simplex virus type 1 vector mediated gene transfer to muscle.
Gene therapy 1995;2(6):385-92.
1995: David J Fink; R Ramakrishnan; Pierfrancesco Marconi; William F Goins; Thomas C Holland; Joseph C Glorioso
Advances in the development of herpes simplex virus-based gene transfer vectors for the nervous system.
Clinical neuroscience (New York, N.Y.) 1995;3(5):284-91.
1994: William F Goins; L R Sternberg; K D Croen; P R Krause; R L Hendricks; David J Fink; Stephen E Straus; Myron M Levine; Joseph C Glorioso
A novel latency-active promoter is contained within the herpes simplex virus type 1 UL flanking repeats.
Journal of virology 1994;68(4):2239-52.
1994: Joseph C Glorioso; William F Goins; Neal A DeLuca; David J Fink
Development of herpes simplex virus as a gene transfer vector for the nervous system.
Gene therapy 1994;1 Suppl 1():S39.
1994: Joseph C Glorioso; William F Goins; C A Meaney; David J Fink; Neal A DeLuca
Gene transfer to brain using herpes simplex virus vectors.
Annals of neurology 1994;35 Suppl():S28-34.
1994: Joseph C Glorioso; William F Goins; David J Fink; Neal A DeLuca
Herpes simplex virus vectors and gene transfer to brain.
Developments in biological standardization 1994;82():79-87.
1993: A M Oyan; K E Dolter; Nina Langeland; William F Goins; Joseph C Glorioso; Lars Haarr; C S Crumpacker
Resistance of herpes simplex virus type 2 to neomycin maps to the N-terminal portion of glycoprotein C.
Journal of virology 1993;67(5):2434-41.
1992: K E Dolter; William F Goins; Myron M Levine; Joseph C Glorioso
Genetic analysis of type-specific antigenic determinants of herpes simplex virus glycoprotein C.
Journal of virology 1992;66(8):4864-73.
1992: David J Fink; L R Sternberg; P C Weber; Marina Mata; William F Goins; Joseph C Glorioso
In vivo expression of beta-galactosidase in hippocampal neurons by HSV-mediated gene transfer.
Human gene therapy 1992;3(1):11-9.
1991: S L Highlander; William F Goins; Stanley Person; Thomas C Holland; Myron M Levine; Joseph C Glorioso
Oligomer formation of the gB glycoprotein of herpes simplex virus type 1.
Journal of virology 1991;65(8):4275-83.