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Burkhard Göke

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Frank T Kolligs; Ulrich Mansmann; Axel Munte; Alexander Crispin; Anno Graser; Burkhard Göke
Risk factors for advanced neoplasia within subcentimetric polyps: implications for diagnostic imaging.
Burkhard Göke; Åsa Hellqvist; Johan G Eriksson; Baptist Gallwitz; Ingrid Gause-Nilsson
Saxagliptin vs. glipizide as add-on therapy in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: long-term (52-week) extension of a 52-week randomised controlled trial.
Anno Graser; Karin Herrmann; Burkhard Göke; Evelyn Lindner; Ulrich Mansmann; Anja Melzer; Dorothea Nagel; Maximilian F Reiser; Jörg Schirra; Petra Stieber; Frank T Kolligs
Magnetic resonance colonography for the detection of colorectal neoplasia in asymptomatic adults.

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2013: Frank T Kolligs; Ulrich Mansmann; Axel Munte; Alexander Crispin; Anno Graser; Burkhard Göke
Risk factors for advanced neoplasia within subcentimetric polyps: implications for diagnostic imaging.
Gut 2013;62(6):863-70.
2013: Burkhard Göke; Åsa Hellqvist; Johan G Eriksson; Baptist Gallwitz; Ingrid Gause-Nilsson
Saxagliptin vs. glipizide as add-on therapy in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: long-term (52-week) extension of a 52-week randomised controlled trial.
International journal of clinical practice 2013;67(4):307-16.
2013: Anno Graser; Karin Herrmann; Burkhard Göke; Evelyn Lindner; Ulrich Mansmann; Anja Melzer; Dorothea Nagel; Maximilian F Reiser; Jörg Schirra; Petra Stieber; Frank T Kolligs
Magnetic resonance colonography for the detection of colorectal neoplasia in asymptomatic adults.
Gastroenterology 2013;144(4):743-750.e2.
2013: Kerstin Knoop; Peter J Nelson; Nathalie Schwenk; Ernst Wagner; Michael J Willhauck; Christian Zach; Christoph Zischek; Patrick Dolp; Burkhard Göke; Markus Hacker; Christine Spitzweg
Stromal targeting of sodium iodide symporter using mesenchymal stem cells allows enhanced imaging and therapy of hepatocellular carcinoma.
Human gene therapy 2013;24(3):306-16.
2013: Jürgen Glas; Burkhard Göke; Torsten Olszak; Julia Seiderer; Johannes Stallhofer; Christian J Steib; Eleni Tsekeri; Martin Wetzke; Stephanie Bues; Darina Czamara; Julia Diegelmann; Matthias Friedrich; Christoph Fries; Florian Beigel; Stephan Brand
IRGM variants and susceptibility to inflammatory bowel disease in the German population.
PloS one 2013;8(1):e54338.
2013: Christian J Steib; Manfred Bilzer; Leonore Gmelin; Burkhard Göke; Alexander L Gerbes
Portal pressure regulation following Kupffer cell activation: control of prostaglandin production by heme oxygenases.
Digestion 2013;87(2):102-9.
2013: Antje Malo; Burkhard Göke; Burkhard Krüger; Constanze H Kubisch
4-Phenylbutyric acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini.
Pancreas 2013;42(1):92-101.
2012: Alexander R Haug; Martin Reincke; Gerwin P Schmidt; Christopher Uebleis; Björn Wängler; Christoph J Auernhammer; Peter Bartenstein; Ramona Cindea-Drimus; Burkhard Göke; Marcus Hacker
The role of 68Ga-DOTATATE PET/CT in suspected neuroendocrine tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(11):1686-92.
2012: Claus Schäfer; Hendrik Seeliger; Andreas Ziesch; Gerald Assmann; Dominik C Bader; Christiane Bruns; Denise Buchner; Enrico N De Toni; Burkhard Göke; Yang Guo; Andreas Jung; Thomas Kirchner; Rüdiger P Laubender; Stephanie Ochs; Andreas Palagyi; Eike Gallmeier
Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma.
Journal of cellular and molecular medicine 2012;16(8):1776-91.
2012: Kathrin Zitzmann; Stephan Brand; Burkhard Göke; Harald Lahm; Gerald Spöttl; George Vlotides; Christoph J Auernhammer
Perifosine-mediated Akt inhibition in neuroendocrine tumor cells: role of specific Akt isoforms.
Endocrine-related cancer 2012;19(3):423-34.
2012: Lydia Kriegl; Antonia Rizzani; Eike Gallmeier; Alexander L Gerbes; Burkhard Göke; Heiko Hermeking; David Horst; Rene Jackstadt; Andreas Jung; Thomas Kirchner; Enrico N De Toni
Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer.
PloS one 2012;7(12):e51654.
2012: Mark op den Winkel; Philip op den Winkel; Markus Rentsch; Julia Sappl; Petra Stieber; Gundula Straub; Christoph J Zech; Burkhard Göke; Rolf Lamerz; Dorothea Nagel; Thomas Nickel; Frank T Kolligs
Prognosis of patients with hepatocellular carcinoma. Validation and ranking of established staging-systems in a large western HCC-cohort.
PloS one 2012;7(10):e45066.
2012: P Dames; Burkhard Göke; Klaus G Parhofer; R Puff; J Seissler; M Weise; A Lechner
Suppression of the nuclear factor Eny2 increases insulin secretion in poorly functioning INS-1E insulinoma cells.
Experimental diabetes research 2012;2012():460869.
2012: Jürgen Glas; Burkhard Göke; Thomas Ochsenkühn; Torsten Olszak; Julia Seiderer; Johannes Stallhofer; Christian J Steib; Cornelia Tillack; Johanna Wagner; Martin Wetzke; Darina Czamara; Julia Diegelmann; Matthias Friedrich; Christoph Fries; Florian Beigel; Stephan Brand
Analysis of IL12B gene variants in inflammatory bowel disease.
PloS one 2012;7(3):e34349.
2012: Jürgen Glas; Burkhard Göke; Nazanin Karbalai; Thomas Ochsenkühn; Torsten Olszak; Julia Seiderer; Johannes Stallhofer; Christian J Steib; Cornelia Tillack; Johanna Wagner; Martin Wetzke; Florian Beigel; Darina Czamara; Julia Diegelmann; Matthias Friedrich; Stephan Brand
PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background.
PloS one 2012;7(3):e33682.
2012: Florian Beigel; Simone Breiteneicher; Burkhard Göke; Rüdiger P Laubender; Beate Löhr; Thomas Ochsenkühn; Fabian Schnitzler; Julia Seiderer; Cornelia Tillack; Maria Weidinger; Stephan Brand
Iron status and analysis of efficacy and safety of ferric carboxymaltose treatment in patients with inflammatory bowel disease.
Digestion 2012;85(1):47-54.
2011: Alexander R Haug; Mona Mustafa; Axel Rominger; Gerwin P Schmidt; Björn Wängler; Christoph J Auernhammer; Peter Bartenstein; Paul Cumming; Burkhard Göke; Marcus Hacker
Treatment with octreotide does not reduce tumor uptake of (68)Ga-DOTATATE as measured by PET/CT in patients with neuroendocrine tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(11):1679-83.
2011: Kathrin Klutz; Reingard Senekowitsch-Schmidtke; Martina Anton; Burkhard Göke; Michael J Willhauck; Nathalie Wunderlich; Christian Zach; Christine Spitzweg
Sodium iodide symporter (NIS)-mediated radionuclide ((131)I, (188)Re) therapy of liver cancer after transcriptionally targeted intratumoral in vivo NIS gene delivery.
Human gene therapy 2011;22(11):1403-12.
2011: Jürgen Glas; Burkhard Göke; Bertram Müller-Myhsok; Thomas Ochsenkühn; Torsten Olszak; Simone Pfennig; Julia Seiderer; Barbara Tengler; Maria Weidinger; Martin Wetzke; Darina Czamara; Julia Diegelmann; Daniel Fischer; Matthias Folwaczny; Florian Beigel; Stephan Brand
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.
Inflammatory bowel diseases 2011;17(9):1917-24.
2011: Kerstin Knoop; Marie Kolokythas; Peter J Nelson; Guido Böning; Dan Draganovici; Franz-Josef Gildehaus; Burkhard Göke; Kathrin Klutz; Ernst Wagner; Michael J Willhauck; Nathalie Wunderlich; Christian Zach; Christine Spitzweg
Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(9):1704-13.
2011: Christoph J Auernhammer; Burkhard Göke
Therapeutic strategies for advanced neuroendocrine carcinomas of jejunum/ileum and pancreatic origin.
Gut 2011;60(7):1009-21.
2011: R Puff; P Dames; M Weise; Burkhard Göke; Jochen Seissler; Klaus G Parhofer; A Lechner
Reduced proliferation and a high apoptotic frequency of pancreatic beta cells contribute to genetically-determined diabetes susceptibility of db/db BKS mice.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2011;43(5):306-11.
2011: Kathrin Zitzmann; Enrico de Toni; Janina von Rüden; Stephan Brand; Burkhard Göke; Rüdiger P Laubender; Christoph J Auernhammer
The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells.
Endocrine-related cancer 2011;18(2):277-85.
2011: Kathrin Klutz; David Schaffert; Michael J Willhauck; Geoffrey K Grünwald; Rudolf Haase; Nathalie Wunderlich; Christian Zach; Franz-Josef Gildehaus; Reingard Senekowitsch-Schmidtke; Burkhard Göke; Ernst Wagner; Manfred Ogris; Christine Spitzweg
Epidermal growth factor receptor-targeted (131)I-therapy of liver cancer following systemic delivery of the sodium iodide symporter gene.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(4):676-85.
2011: Jürgen Glas; Julia Seiderer; Christian Markus; Simone Pfennig; Martin Wetzke; Ekaterini Paschos; Burkhard Göke; Thomas Ochsenkühn; Bertram Müller-Myhsok; Julia Diegelmann; Darina Roeske; Stephan Brand
Role of PPARG gene variants in inflammatory bowel disease.
Inflammatory bowel diseases 2011;17(4):1057-8.
2011: Eike Gallmeier; Patrick C Hermann; Maria-Theresa Mueller; Juan G Machado; Andreas Ziesch; Enrico N De Toni; Andreas Palagyi; Christian Eisen; Joachim W Ellwart; Jose Rivera; Belen Rubio-Viqueira; Manuel Hidalgo; Fred Bunz; Burkhard Göke; Christopher Heeschen
Inhibition of ataxia telangiectasia- and Rad3-related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor-initiating cell fraction.
Stem cells (Dayton, Ohio) 2011;29(3):418-29.
2011: Sonja Kirchhoff; M Nicolaus; Jörg Schirra; Maximilian F Reiser; Burkhard Göke; Andreas Lienemann
Assessment of colon motility using simultaneous manometric and functional cine-MRI analysis: preliminary results.
Abdominal imaging 2011;36(1):24-30.
2011: Nadja Herbach; Martina Bergmayr; Burkhard Göke; Eckhard Wolf; Ruediger Wanke
Postnatal development of numbers and mean sizes of pancreatic islets and beta-cells in healthy mice and GIPR(dn) transgenic diabetic mice.
PloS one 2011;6(7):e22814.
2011: Frank T Kolligs; Alexander Crispin; Axel Munte; Andreas Wagner; Ulrich Mansmann; Burkhard Göke
Risk of advanced colorectal neoplasia according to age and gender.
PloS one 2011;6(5):e20076.
2011: Jürgen Glas; Julia Seiderer; Christoph Fries; Cornelia Tillack; Simone Pfennig; Maria Weidinger; Florian Beigel; Torsten Olszak; Ulrich Lass; Burkhard Göke; Thomas Ochsenkühn; Christiane Wolf; Peter Lohse; Bertram Müller-Myhsok; Julia Diegelmann; Darina Czamara; Stephan Brand
CEACAM6 gene variants in inflammatory bowel disease.
PloS one 2011;6(4):e19319.
2011: M Nicolaus; Julia Brödl; Rainer Linke; Hans-Juergen Woerle; Burkhard Göke; Jörg Schirra
Endogenous GLP-1 regulates postprandial glycemia in humans: relative contributions of insulin, glucagon, and gastric emptying.
The Journal of clinical endocrinology and metabolism 2011;96(1):229-36.
2011: Florian Beigel; Fabian Schnitzler; Rüdiger Paul Laubender; Simone Pfennig; Maria Weidinger; Burkhard Göke; Julia Seiderer; Thomas Ochsenkühn; Stephan Brand
Formation of antinuclear and double-strand DNA antibodies and frequency of lupus-like syndrome in anti-TNF-α antibody-treated patients with inflammatory bowel disease.
Inflammatory bowel diseases 2011;17(1):91-8.
2011: Michael J Willhauck; Dennis J O Kane; Nathalie Wunderlich; Burkhard Göke; Christine Spitzweg
Stimulation of retinoic acid-induced functional sodium iodide symporter (NIS) expression and cytotoxicity of ¹³¹I by carbamazepine in breast cancer cells.
Breast cancer research and treatment 2011;125(2):377-86.
2010: Julia Diegelmann; Julia Seiderer; Jan-Hendrik Niess; Dirk Haller; Burkhard Göke; Hans-Christian Reinecker; Stephan Brand
Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation.
Inflammatory bowel diseases 2010;16(11):1871-81.
2010: Jutta Maria Nagel; Lydia Kriegl; David Horst; Jutta Engel; Shiva Gautam; Christos S Mantzoros; Thomas Kirchner; Burkhard Göke; Frank T Kolligs
γ-Catenin is an independent prognostic marker in early stage colorectal cancer.
International journal of colorectal disease 2010;25(11):1301-9.
2010: S Nölting; M Nicolaus; Jürgen Behr; R Baumgartner; H Mete; Peter Boekstegers; K Herrmann; Daniel Theisen; Michael Lehrke; Burkhard Göke; Jörg Schirra; Christoph J Auernhammer
[Progressive dyspnoea in two patients with carcinoid syndrome].
Der Internist 2010;51(11):1439-45.
2010: Matthias Jürgens; Stephan Brand; Levent Filik; Christoph Hübener; Uwe Hasbargen; Florian Beigel; Cornelia Tillack; Burkhard Göke; Thomas Ochsenkühn; Julia Seiderer
Safety of adalimumab in Crohn's disease during pregnancy: case report and review of the literature.
Inflammatory bowel diseases 2010;16(10):1634-6.
2010: Alexander R Haug; Christoph J Auernhammer; Björn Wängler; Gerwin P Schmidt; Christopher Uebleis; Burkhard Göke; Paul Cumming; Peter Bartenstein; Reinhold Tiling; Marcus Hacker
68Ga-DOTATATE PET/CT for the early prediction of response to somatostatin receptor-mediated radionuclide therapy in patients with well-differentiated neuroendocrine tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1349-56.
2010: Kathrin Zitzmann; Janina von Rüden; Stephan Brand; Burkhard Göke; Jennifer Lichtl; Gerald Spöttl; Christoph J Auernhammer
Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease.
Cancer letters 2010;295(1):100-9.
2010: Matthias Jürgens; Rüdiger P Laubender; Franziska Hartl; Maria Weidinger; Julia Seiderer; Johanna Wagner; Martin Wetzke; Florian Beigel; Simone Pfennig; Johannes Stallhofer; Fabian Schnitzler; Cornelia Tillack; Peter Lohse; Burkhard Göke; Jürgen Glas; Thomas Ochsenkühn; Stephan Brand
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis.
The American journal of gastroenterology 2010;105(8):1811-9.
2010: Ramona Puff; Petra Dames; Michaela Weise; Burkhard Göke; Klaus Parhofer; Andreas Lechner
No non-redundant function of suppressor of cytokine signaling 2 in insulin producing β-cells.
Islets 2010;2(4):252-7.
2010: Matthias Jürgens; Stephan Brand; Rüdiger P Laubender; Julia Seiderer; Jürgen Glas; Martin Wetzke; Johanna Wagner; Simone Pfennig; Cornelia Tillack; Florian Beigel; Maria Weidinger; Fabian Schnitzler; Martin E Kreis; Burkhard Göke; Peter Lohse; Karin Herrmann; Thomas Ochsenkühn
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype.
Journal of gastroenterology 2010;45(7):721-31.
2010: Christian J Steib; Manfred Bilzer; Mark op den Winkel; Susanne Pfeiler; Anna C Hartmann; Martin Hennenberg; Burkhard Göke; Alexander L Gerbes
Treatment with the leukotriene inhibitor montelukast for 10 days attenuates portal hypertension in rat liver cirrhosis.
Hepatology (Baltimore, Md.) 2010;51(6):2086-96.
2010: Simone Renner; Christiane Fehlings; Nadja Herbach; Andreas Hofmann; Dagmar C von Waldthausen; Barbara Kessler; Karin Ulrichs; Irina Chodnevskaja; Vasiliy Moskalenko; Werner M Amselgruber; Burkhard Göke; Alexander Pfeifer; Rüdiger Wanke; Eckhard Wolf
Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function.
Diabetes 2010;59(5):1228-38.
2010: Burkhard Göke
What are the potential benefits of clinical beta-cell imaging in diabetes mellitus?
Current pharmaceutical design 2010;16(14):1547-9.
2010: Christian J Steib; Manfred Bilzer; Josef M Härtl; Frigga Beitinger; Veit Gülberg; Burkhard Göke; Alexander L Gerbes
Kupffer cell activation by hydrogen peroxide: a new mechanism of portal pressure increase.
Shock (Augusta, Ga.) 2010;33(4):412-8.
2010: Jürgen Glas; Julia Seiderer; Cornelia Tillack; Simone Pfennig; Florian Beigel; Matthias Jürgens; Torsten Olszak; Rüdiger P Laubender; Maria Weidinger; Bertram Müller-Myhsok; Burkhard Göke; Thomas Ochsenkühn; Peter Lohse; Julia Diegelmann; Darina Czamara; Stephan Brand
The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.
PloS one 2010;5(12):e14466.
2010: Julia Diegelmann; Florian Beigel; Kathrin Zitzmann; Artur Kaul; Burkhard Göke; Christoph J Auernhammer; Ralf Bartenschlager; Helmut M Diepolder; Stephan Brand
Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus.
PloS one 2010;5(12):e15200.
2010: Andreas Palagyi; Kornelia Neveling; Ursula Plinninger; Andreas Ziesch; Bianca-Sabrina Targosz; Gerald U Denk; Stephanie Ochs; Antonia Rizzani; Daniel Meier; Wolfgang E Thasler; Helmut Hanenberg; Enrico N De Toni; Florian Bassermann; Claus Schäfer; Burkhard Göke; Detlev Schindler; Eike Gallmeier
Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand crosslinking agents.
Molecular cancer 2010;9():127.
2010: Jürgen Glas; Julia Seiderer; Melinda Nagy; Christoph Fries; Florian Beigel; Maria Weidinger; Simone Pfennig; Wolfram Klein; Jörg T Epplen; Peter Lohse; Matthias Folwaczny; Burkhard Göke; Thomas Ochsenkühn; Julia Diegelmann; Bertram Müller-Myhsok; Darina Roeske; Stephan Brand
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.
PloS one 2010;5(4):e10373.
2010: Martin Storr; Dominik Emmerdinger; Julia Diegelmann; Simone Pfennig; Thomas Ochsenkühn; Burkhard Göke; Peter Lohse; Stephan Brand
The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.
PloS one 2010;5(2):e9453.
2009: Claus Schäfer; Christoph J Zech; Burkhard Göke
[Obstructive jaundice: harmless stone or malignant tumour? Diagnosis and management from a gastroenterologist's perspective].
MMW Fortschritte der Medizin 2009;151(49-50):33-6.
2009: Yong-Yu Li; Stephanie Ochs; Zhi-Rong Gao; A Malo; Chang-Jie Chen; Shuai Lv; Eike Gallmeier; Burkhard Göke; Claus Schäfer
Regulation of HSP60 and the role of MK2 in a new model of severe experimental pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology 2009;297(5):G981-9.
2009: Andreas Herbst; Simone Helferich; Andrea Behrens; Burkhard Göke; Frank T Kolligs
The transcription factor ITF-2A induces cell cycle arrest via p21(Cip1).
Biochemical and biophysical research communications 2009;387(4):736-40.
2009: Kathrin Klutz; Verena Russ; Michael J Willhauck; Nathalie Wunderlich; Christian Zach; Franz-Josef Gildehaus; Burkhard Göke; Ernst Wagner; Manfred Ogris; Christine Spitzweg
Targeted radioiodine therapy of neuroblastoma tumors following systemic nonviral delivery of the sodium iodide symporter gene.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6079-86.
2009: Julia Dambacher; Florian Beigel; Kathrin Zitzmann; Enrico N De Toni; Burkhard Göke; Helmut M Diepolder; Christoph J Auernhammer; Stephan Brand
The role of the novel Th17 cytokine IL-26 in intestinal inflammation.
Gut 2009;58(9):1207-17.
2009: Michael Lehrke; Alexander Becker; Martin Greif; Renee Stark; Rüdiger P Laubender; Franz von Ziegler; Corinna Lebherz; Janine Tittus; Maximilian Reiser; Hans-Christoph Becker; Burkhard Göke; Alexander W Leber; Klaus G Parhofer; Uli C Broedl
Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(2):339-44.
2009: Andreas Herbst; Bommer Guido; Lydia Kriegl; Andreas Jung; Andrea Behrens; Endy Csanadi; Markus Gerhard; Christian Bolz; Rainer Riesenberg; Wolfgang Zimmermann; Wolfgang Dietmaier; Isabella Wolf; Thomas Brabletz; Burkhard Göke; Frank T Kolligs
ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition.
Gastroenterology 2009;137(2):639-48, 648.e1-9.
2009: Florian Beigel; Matthias Jürgens; Levent Filik; Lutz Bader; Christian Lück; Burkhard Göke; Thomas Ochsenkühn; Stephan Brand; Julia Seiderer
Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease.
Inflammatory bowel diseases 2009;15(8):1240-4.
2009: Florian Beigel; Matthias Jürgens; Cornelia Tillack; Marion Subklewe; Doris Mayr; Burkhard Göke; Stephan Brand; Thomas Ochsenkühn
Hepatosplenic T-cell lymphoma in a patient with Crohn's disease.
Nature reviews. Gastroenterology & hepatology 2009;6(7):433-6.
2009: Helga-Paula Török; Jürgen Glas; Ilona Endres; Laurian Tonenchi; Molla Y Teshome; Martin Wetzke; Wolfram Klein; Peter Lohse; Thomas Ochsenkühn; Matthias Folwaczny; Burkhard Göke; Christian Folwaczny; Bertram Müller-Myhsok; Stephan Brand
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease.
The American journal of gastroenterology 2009;104(7):1723-33.
2009: Jürgen Glas; Johannes Stallhofer; Stephan Ripke; Martin Wetzke; Simone Pfennig; Wolfram Klein; Jörg T Epplen; Thomas Griga; Uwe Schiemann; Martin Lacher; Sibylle Koletzko; Matthias Folwaczny; Peter Lohse; Burkhard Göke; Thomas Ochsenkühn; Bertram Müller-Myhsok; Stephan Brand
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.
The American journal of gastroenterology 2009;104(7):1737-44.
2009: Jörg Schirra; M Nicolaus; Hans-Juergen Woerle; C Struckmeier; Martin Katschinski; Burkhard Göke
GLP-1 regulates gastroduodenal motility involving cholinergic pathways.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2009;21(6):609-18, e21-2.
2009: Alexander Haug; Christoph J Auernhammer; Björn Wängler; Reinhold Tiling; Gerwin Schmidt; Burkhard Göke; Peter Bartenstein; Gabriele Pöpperl
Intraindividual comparison of 68Ga-DOTA-TATE and 18F-DOPA PET in patients with well-differentiated metastatic neuroendocrine tumours.
European journal of nuclear medicine and molecular imaging 2009;36(5):765-70.
2009: S R Mucha; A Rizzani; Alexander L Gerbes; P Camaj; Wolfgang E Thasler; C J Bruns; Sören Eichhorst; Eike Gallmeier; Frank T Kolligs; Burkhard Göke; Enrico N De Toni
JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand.
Gut 2009;58(5):688-98.
2009: Sebastian Baehs; Andreas Herbst; Susanne E Thieme; Claudia Perschl; Andrea Behrens; Silvio Scheel; Andreas Jung; Thomas Brabletz; Burkhard Göke; Helmut Blum; Frank T Kolligs
Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells.
Cancer letters 2009;276(2):152-9.
2009: Jürgen Glas; Julia Seiderer; Giulia Pasciuto; Cornelia Tillack; Julia Diegelmann; Simone Pfennig; Astrid Konrad; Silke Schmechel; Martin Wetzke; Helga-Paula Török; Johannes Stallhofer; Matthias Jürgens; Thomas Griga; Wolfram Klein; Jörg T Epplen; Uwe Schiemann; Thomas Mussack; Peter Lohse; Burkhard Göke; Thomas Ochsenkühn; Matthias Folwaczny; Bertram Müller-Myhsok; Stephan Brand
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.
The American journal of gastroenterology 2009;104(3):665-72.
2009: Martin Storr; D Emmerdinger; J Diegelmann; Birol Yüce; Simone Pfennig; Thomas Ochsenkühn; Burkhard Göke; Peter Lohse; Stephan Brand
The role of fatty acid hydrolase gene variants in inflammatory bowel disease.
Alimentary pharmacology & therapeutics 2009;29(5):542-51.
2009: Anno Graser; Petra Stieber; D Nagel; C Schäfer; D Horst; Hans-Christoph Becker; Konstantin Nikolaou; A Lottes; S Geisbüsch; H Kramer; A C Wagner; H Diepolder; Jörg Schirra; H J Roth; D Seidel; Burkhard Göke; Maximilian F Reiser; Frank T Kolligs
Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population.
Gut 2009;58(2):241-8.
2009: Michael Lehrke; Martin Greif; Uli C Broedl; Corinna Lebherz; Rüdiger P Laubender; Alexander Becker; Franz von Ziegler; Janine Tittus; Maximilian Reiser; Hans-Christoph Becker; Burkhard Göke; Gerhard Steinbeck; Alexander Leber; Klaus G Parhofer
MMP-1 serum levels predict coronary atherosclerosis in humans.
Cardiovascular diabetology 2009;8():50.
2009: Uli C Broedl; Corinna Lebherz; Michael Lehrke; Renee Stark; Martin Greif; Alexander Becker; Franz von Ziegler; Janine Tittus; Maximilian Reiser; Hans-Christoph Becker; Burkhard Göke; Klaus G Parhofer; Alexander W Leber
Low adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques.
PloS one 2009;4(3):e4733.
2009: Andrei Sibaev; Birol Yüce; Markus Kemmer; Luc Van Nassauw; Ulli Broedl; Hans-Dieter Allescher; Burkhard Göke; Jean-Pierre Timmermans; Martin Storr
Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(1):G119-28.
2008: Hans-Juergen Woerle; Max Albrecht; Rainer Linke; Silvia Zschau; Christoph Neumann; Mathias Nicolaus; John E Gerich; Burkhard Göke; Joerg Schirra
Impaired hyperglycemia-induced delay in gastric emptying in patients with type 1 diabetes deficient for islet amyloid polypeptide.
Diabetes care 2008;31(12):2325-31.
2008: Burkhard Göke; K Hershon; D Kerr; A Calle Pascual; A Schweizer; J Foley; Q Shao; S Dejager
Efficacy and safety of vildagliptin monotherapy during 2-year treatment of drug-naïve patients with type 2 diabetes: comparison with metformin.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(12):892-5.
2008: Cornelia Tillack; Julia Seiderer; Stephan Brand; Burkhard Göke; Maximilian F Reiser; Claus Schaefer; Helmut Diepolder; Thomas Ochsenkühn; Karin A Herrmann
Correlation of magnetic resonance enteroclysis (MRE) and wireless capsule endoscopy (CE) in the diagnosis of small bowel lesions in Crohn's disease.
Inflammatory bowel diseases 2008;14(9):1219-28.
2008: Enrico N De Toni; Susanne E Thieme; Andreas Herbst; Andrea Behrens; Petra Stieber; Andreas Jung; Helmut Blum; Burkhard Göke; Frank T Kolligs
OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4713-8.
2008: Martin A Storr; Catherine M Keenan; Dominik Emmerdinger; Hong Zhang; Birol Yüce; Andrei Sibaev; Federico Massa; Nancy E Buckley; Beat Lutz; Burkhard Göke; Stephan Brand; Kamala D Patel; Keith Sharkey
Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors.
Journal of molecular medicine (Berlin, Germany) 2008;86(8):925-36.
2008: Thomas Pusl; Nadine Wild; Timo Vennegeerts; Ralf Wimmer; Burkhard Göke; Stephan Brand; Christian Rust
Free fatty acids sensitize hepatocytes to bile acid-induced apoptosis.
Biochemical and biophysical research communications 2008;371(3):441-5.
2008: Helga-Paula Török; Burkhard Göke; Astrid Konrad
Pharmacogenetics of Crohn's disease.
Pharmacogenomics 2008;9(7):881-93.
2008: Michael J Willhauck; Bibi-Rana Sharif Samani; Ingo Wolf; Reingard Senekowitsch-Schmidtke; Hans-Jürgen Stark; Geerd J Meyer; WH Knapp; Burkhard Göke; John C Morris; Christine Spitzweg
The potential of 211Astatine for NIS-mediated radionuclide therapy in prostate cancer.
European journal of nuclear medicine and molecular imaging 2008;35(7):1272-81.
2008: Andrei Sibaev; Birol Yüce; Hans-Dieter Allescher; Burkhard Göke; Martin Storr
A new electrophysiological tool to investigate the spatial neuronal projections within the myenteric ascending reflex of the mouse colon.
Clinical and experimental pharmacology & physiology 2008;35(7):744-50.
2008: Michael J Willhauck; Bibi Sharif-Samani; Reingard Senekowitsch-Schmidtke; Nathalie Wunderlich; Burkhard Göke; John C Morris; Christine Spitzweg
Functional sodium iodide symporter expression in breast cancer xenografts in vivo after systemic treatment with retinoic acid and dexamethasone.
Breast cancer research and treatment 2008;109(2):263-72.
2008: Julia Seiderer; Julia Dambacher; Dorothea Leistner; Cornelia Tillack; Jürgen Glas; Jan-Hendrik Niess; Simone Pfennig; Matthias Jürgens; Bertram Müller-Myhsok; Burkhard Göke; Thomas Ochsenkühn; Peter Lohse; Hans-Christian Reinecker; Stephan Brand
Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease.
Clinical immunology (Orlando, Fla.) 2008;127(1):49-55.
2008: Julia Seiderer; Ira Elben; Julia Diegelmann; Jürgen Glas; Johannes Stallhofer; Cornelia Tillack; Simone Pfennig; Matthias Jürgens; Silke Schmechel; Astrid Konrad; Burkhard Göke; Thomas Ochsenkühn; Bertram Müller-Myhsok; Peter Lohse; Stephan Brand
Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD.
Inflammatory bowel diseases 2008;14(4):437-45.
2008: C H Kubisch; W H Flatz; Burkhard Göke
[Incidentaloma of the pancreas].
Zeitschrift für Gastroenterologie 2008;46(3):292-6.
2008: Burkhard Göke
Islet cell function: alpha and beta cells--partners towards normoglycaemia.
International journal of clinical practice. Supplement 2008;(159):2-7.
2008: Burkhard Göke
Islet cell function is as interesting as insulin resistance for T2DM treatment options.
International journal of clinical practice. Supplement 2008;(159):1.
2008: Julia Dambacher; Florian Beigel; Kathrin Zitzmann; Malte H J Heeg; Burkhard Göke; Helmut M Diepolder; Christoph J Auernhammer; Stephan Brand
The role of interleukin-22 in hepatitis C virus infection.
Cytokine 2008;41(3):209-16.
2008: Jürgen Glas; Astrid Konrad; Silke Schmechel; Julia Dambacher; Julia Seiderer; Frieder Schroff; Martin Wetzke; Darina Roeske; Helga-Paula Török; Laurian Tonenchi; Simone Pfennig; Dirk Haller; Thomas Griga; Wolfram Klein; Jörg T Epplen; Christian Folwaczny; Peter Lohse; Burkhard Göke; Thomas Ochsenkühn; Thomas Mussack; Matthias Folwaczny; Bertram Müller-Myhsok; Stephan Brand
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.
The American journal of gastroenterology 2008;103(3):682-91.
2008: Jutta M Berster; Burkhard Göke
Type 2 diabetes mellitus as risk factor for colorectal cancer.
Archives of physiology and biochemistry 2008;114(1):84-98.
2008: Silke Schmechel; Astrid Konrad; Julia Diegelmann; Jürgen Glas; Martin Wetzke; Ekaterini Paschos; Peter Lohse; Burkhard Göke; Stephan Brand
Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status.
Inflammatory bowel diseases 2008;14(2):204-12.
2008: Michael J Willhauck; B R Sharif Samani; K Klutz; Neziha Cengic; Ingo Wolf; L Mohr; M Geissler; Reingard Senekowitsch-Schmidtke; Burkhard Göke; John C Morris; Christine Spitzweg
Alpha-fetoprotein promoter-targeted sodium iodide symporter gene therapy of hepatocellular carcinoma.
Gene therapy 2008;15(3):214-23.
2008: Michael Lehrke; Uli C Broedl; Ingeborg M Biller-Friedmann; Michael Vogeser; Volkmar Henschel; Kirsten Nassau; Burkhard Göke; Erich Kilger; Klaus G Parhofer
Serum concentrations of cortisol, interleukin 6, leptin and adiponectin predict stress induced insulin resistance in acute inflammatory reactions.
Critical care (London, England) 2008;12(6):R157.
2008: Hans-Juergen Woerle; M Albrecht; R Linke; S Zschau; C Neumann; M Nicolaus; John E Gerich; Burkhard Göke; Jörg Schirra
Importance of changes in gastric emptying for postprandial plasma glucose fluxes in healthy humans.
American journal of physiology. Endocrinology and metabolism 2008;294(1):E103-9.
2007: Astrid Konrad; Michael Lehrke; Veronika Schachinger; Frank Seibold; Renee Stark; Thomas Ochsenkühn; Klaus G Parhofer; Burkhard Göke; Uli C Broedl
Resistin is an inflammatory marker of inflammatory bowel disease in humans.
European journal of gastroenterology & hepatology 2007;19(12):1070-4.
2007: Julia Seiderer; Karin Herrmann; Helmut M Diepolder; Stefan O Schoenberg; Andreas C Wagner; Burkhard Göke; Thomas Ochsenkühn; Claus Schäfer
Double-balloon enteroscopy versus magnetic resonance enteroclysis in diagnosing suspected small-bowel Crohn's disease: results of a pilot study.
Scandinavian journal of gastroenterology 2007;42(11):1376-85.
2007: Michael J Willhauck; Bibi-Rana Sharif Samani; Franz-Josef Gildehaus; Ingo Wolf; Reingard Senekowitsch-Schmidtke; Hans-Jürgen Stark; Burkhard Göke; John C Morris; Christine Spitzweg
Application of 188rhenium as an alternative radionuclide for treatment of prostate cancer after tumor-specific sodium iodide symporter gene expression.
The Journal of clinical endocrinology and metabolism 2007;92(11):4451-8.
2007: Burkhard Göke; Ingrid Gause-Nilsson; Anders Persson
The effects of tesaglitazar as add-on treatment to metformin in patients with poorly controlled type 2 diabetes.
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease 2007;4(3):204-13.
2007: B Yuece; Andrei Sibaev; Uli C Broedl; Giovanni Marsicano; Burkhard Göke; Beat Lutz; Hans-Dieter Allescher; Martin Storr
Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2007;19(9):744-53.
2007: Julia Seiderer; Julia Dambacher; B Kühnlein; Simone Pfennig; Astrid Konrad; Helga-Paula Török; D Haller; Burkhard Göke; Thomas Ochsenkühn; Peter Lohse; Stephan Brand
The role of the selenoprotein S (SELS) gene -105G>A promoter polymorphism in inflammatory bowel disease and regulation of SELS gene expression in intestinal inflammation.
Tissue antigens 2007;70(3):238-46.
2007: Julia Dambacher; Florian Beigel; Julia Seiderer; Dirk Haller; Burkhard Göke; Christoph J Auernhammer; Stephan Brand
Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
Gut 2007;56(9):1257-65.
2007: Birol Yüce; Andrei Sibaev; Andreas Haaken; Dieter Saur; Hans-Dieter Allescher; Burkhard Göke; Jean-Pierre Timmermans; Martin Storr
ORL-1 receptor mediates the action of nociceptin on ascending myenteric reflex pathways in rats.
Gastroenterology 2007;133(2):574-86.
2007: Christian J Steib; Alexander L Gerbes; Markus Bystron; Mark Op den Winkel; Josef Härtl; Frigga Roggel; Thomas Prüfer; Burkhard Göke; Manfred Bilzer
Kupffer cell activation in normal and fibrotic livers increases portal pressure via thromboxane A(2).
Journal of hepatology 2007;47(2):228-38.
2007: Hans-Juergen Woerle; Christoph Neumann; Silvia Zschau; Stephanie Tenner; Andrea Irsigler; Jörg Schirra; John E Gerich; Burkhard Göke
Impact of fasting and postprandial glycemia on overall glycemic control in type 2 diabetes Importance of postprandial glycemia to achieve target HbA1c levels.
Diabetes research and clinical practice 2007;77(2):280-5.
2007: M Nicolaus; Jörg Schirra; Burkhard Göke
[Reflux disease: standards, news and trends].
MMW Fortschritte der Medizin 2007;149(29-30):51-4.
2007: Kathrin Zitzmann; Stephan Brand; Enrico N De Toni; Sebastian Baehs; Burkhard Göke; Jennifer Meinecke; Gerald Spöttl; H H D Meyer; Christoph J Auernhammer
SOCS1 silencing enhances antitumor activity of type I IFNs by regulating apoptosis in neuroendocrine tumor cells.
Cancer research 2007;67(10):5025-32.
2007: Julia Seiderer; Stephan Brand; Julia Dambacher; Simone Pfennig; M Jürgens; Burkhard Göke; Thomas Ochsenkühn
Adalimumab in patients with Crohn's disease--safety and efficacy in an open-label single centre study.
Alimentary pharmacology & therapeutics 2007;25(7):787-96.
2007: Enrico N De Toni; Christian Kuntzen; Alexander L Gerbes; Wolfgang E Thasler; Nilüfer Sonuc; Simon R Mucha; Peter Camaj; Christiane Bruns; Burkhard Göke; Sören Eichhorst
P60-c-src suppresses apoptosis through inhibition of caspase 8 activation in hepatoma cells, but not in primary hepatocytes.
Journal of hepatology 2007;46(4):682-91.
2007: Uli C Broedl; Veronika Schachinger; Arno Lingenhel; Michael Lehrke; Renee Stark; Frank Seibold; Burkhard Göke; Florian Kronenberg; Klaus G Parhofer; Astrid Konrad-Zerna
Apolipoprotein A-IV is an independent predictor of disease activity in patients with inflammatory bowel disease.
Inflammatory bowel diseases 2007;13(4):391-7.
2007: Stephan Brand; Julia Dambacher; Florian Beigel; Kathrin Zitzmann; Malte H J Heeg; Thomas S Weiss; Thomas Prüfer; Torsten Olszak; Christian J Steib; Martin Storr; Burkhard Göke; Helmut M Diepolder; Manfred Bilzer; Wolfgang E Thasler; Christoph J Auernhammer
IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(4):G1019-28.
2007: C Schäfer; B Razziourrouh; Helmut M Diepolder; Burkhard Göke
B-cell lymphoma with bowel-to-bowel penetration diagnosed by double-balloon endoscopy.
Endoscopy 2007;39 Suppl 1():E204.
2007: Christoph J Auernhammer; Burkhard Göke
Medical treatment of gastrinomas.
Wiener klinische Wochenschrift 2007;119(19-20):609-15.
2007: Jürgen Glas; Julia Seiderer; Martin Wetzke; Astrid Konrad; Helga-Paula Török; Silke Schmechel; Laurian Tonenchi; Christine Grassl; Julia Dambacher; Simone Pfennig; Kerstin Maier; Thomas Griga; Wolfram Klein; Jörg T Epplen; Uwe Schiemann; Christian Folwaczny; Peter Lohse; Burkhard Göke; Thomas Ochsenkühn; Bertram Müller-Myhsok; Matthias Folwaczny; Thomas Mussack; Stephan Brand
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.
PloS one 2007;2(9):e819.
2007: Thomas Helmberger; Selin Dogan; Gundula Straub; Angelika Schrader; Christoph Jüngst; Maximilian Reiser; Tobias Waggershauser; Tobias F Jakobs; Ralf-Thorsten Hoffmann; Florian Löhe; Christian Graeb; Horst G Rau; Rolf Schauer; Karl-Walter Jauch; Wolfgang H Caselmann; Burkhard Göke; Dieter Jüngst
Liver resection or combined chemoembolization and radiofrequency ablation improve survival in patients with hepatocellular carcinoma.
Digestion 2007;75(2-3):104-12.
2007: Kathrin Zitzmann; Enrico N De Toni; Stephan Brand; Burkhard Göke; Jennifer Meinecke; Gerald Spöttl; H H D Meyer; Christoph J Auernhammer
The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells.
Neuroendocrinology 2007;85(1):54-60.
2007: Julia Dambacher; Tanja Staudinger; Julia Seiderer; Zeljka Sisic; Fabian Schnitzler; Simone Pfennig; Katrin Hofbauer; Astrid Konrad; Cornelia Tillack; Jan-Michel Otte; Joachim Diebold; Burkhard Göke; Thomas Ochsenkühn; Peter Lohse; Stephan Brand
Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease.
Inflammatory bowel diseases 2007;13(1):71-82.
2006: Maike Wallner; Andreas Herbst; Andrea Behrens; Alexander Crispin; Petra Stieber; Burkhard Göke; Rolf Lamerz; Frank T Kolligs
Methylation of serum DNA is an independent prognostic marker in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7347-52.
2006: Julia Seiderer; Stephan Brand; Karin A Herrmann; Fabian Schnitzler; Rudolf A. Hatz; Alexander Crispin; Simone Pfennig; Stefan O Schoenberg; Burkhard Göke; Peter Lohse; Thomas Ochsenkuhn
Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study.
Inflammatory bowel diseases 2006;12(12):1114-21.
2006: Julia Seiderer; Fabian Schnitzler; Stephan Brand; Tanja Staudinger; Simone Pfennig; Karin Herrmann; Katrin Hofbauer; Julia Dambacher; Cornelia Tillack; Michael Sackmann; Burkhard Göke; Peter Lohse; Thomas Ochsenkühn
Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis.
Scandinavian journal of gastroenterology 2006;41(12):1421-32.
2006: J M Nagel; Burkhard Göke
[Colorectal carcinoma screening in patients with type 2 diabetes mellitus].
Zeitschrift für Gastroenterologie 2006;44(11):1153-65.
2006: D Thalmaier; Julia Dambacher; Julia Seiderer; Astrid Konrad; Veronika Schachinger; Simone Pfennig; Jan-Michel Otte; Alexander Crispin; Burkhard Göke; Thomas Ochsenkühn; Peter Lohse; Stephan Brand
The +1059G/C polymorphism in the C-reactive protein (CRP) gene is associated with involvement of the terminal ileum and decreased serum CRP levels in patients with Crohn's disease.
Alimentary pharmacology & therapeutics 2006;24(7):1105-15.
2006: Jutta M Nagel; Anne B Tietz; Burkhard Göke; Klaus G Parhofer
The effect of telmisartan on glucose and lipid metabolism in nondiabetic, insulin-resistant subjects.
Metabolism: clinical and experimental 2006;55(9):1149-54.
2006: Andrei Sibaev; Birol Yüce; Jörg Schirra; Burkhard Göke; Hans-Dieter Allescher; Martin Storr
Are gap junctions truly involved in inhibitory neuromuscular interaction in mouse proximal colon?
Clinical and experimental pharmacology & physiology 2006;33(8):740-5.
2006: Kathrin Zitzmann; Stephan Brand; Sebastian Baehs; Burkhard Göke; Jennifer Meinecke; Gerald Spöttl; Heinrich Meyer; Christoph J Auernhammer
Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells.
Biochemical and biophysical research communications 2006;344(4):1334-41.
2006: Andrei Sibaev; Federico Massa; Birol Yüce; Giovanni Marsicano; Hans-Anton Lehr; Beat Lutz; Burkhard Göke; Hans-Dieter Allescher; Martin Storr
CB1 and TRPV1 receptors mediate protective effects on colonic electrophysiological properties in mice.
Journal of molecular medicine (Berlin, Germany) 2006;84(6):513-20.
2006: Anne Barbara Tietz; Antje Malo; Joachim Diebold; Alexey Kotlyarov; Andreas Herbst; Frank T Kolligs; Barbara Brandt-Nedelev; Walter Halangk; Matthias Gaestel; Burkhard Göke; Claus Schäfer
Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(6):G1298-306.
2006: Axel Ulsenheimer; Jörg Schirra; Burkhard Göke; Martin Storr
Enterothorax mimicking pleural effusion.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2006;25(3):146.
2006: Thomas Ochsenkühn; Cornelia Tillack; Herbert Stepp; Joachim Diebold; Stephan J Ott; Reinhold Baumgartner; Stephan Brand; Burkhard Göke; Michael Sackmann
Low frequency of colorectal dysplasia in patients with long-standing inflammatory bowel disease colitis: detection by fluorescence endoscopy.
Endoscopy 2006;38(5):477-82.
2006: Julia Seiderer; Christoph J Zech; Joachim Diebold; Stefan O Schoenberg; Stephan Brand; Cornelia Tillack; Burkhard Göke; Thomas Ochsenkühn
Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy.
European journal of gastroenterology & hepatology 2006;18(5):553-5.
2006: Stephan Brand; Florian Beigel; Torsten Olszak; Kathrin Zitzmann; Sören Eichhorst; Jan-Michel Otte; Helmut M Diepolder; Andreas Marquardt; Wolfgang Jagla; Andreas Popp; Stéphane Leclair; Karin Herrmann; Julia Seiderer; Thomas Ochsenkühn; Burkhard Göke; Christoph J Auernhammer; Julia Dambacher
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(4):G827-38.
2006: Fabian Schnitzler; Stephan Brand; Tanja Staudinger; Simone Pfennig; Katrin Hofbauer; Julia Seiderer; Cornelia Tillack; Burkhard Göke; Thomas Ochsenkühn; Peter Lohse
Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease.
Immunogenetics 2006;58(2-3):99-106.
2006: Carsten Otto; B Otto; Burkhard Göke; A F H Pfeiffer; Michael Lehrke; M Vogeser; J Spranger; Klaus G Parhofer
Increase in adiponectin levels during pioglitazone therapy in relation to glucose control, insulin resistance as well as ghrelin and resistin levels.
Journal of endocrinological investigation 2006;29(3):231-6.
2006: Stephan Brand; Torsten Olszak; Florian Beigel; Joachim Diebold; Jan-Michel Otte; Sören Eichhorst; Burkhard Göke; Julia Dambacher
Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells.
Journal of cellular biochemistry 2006;97(4):709-23.
2006: Martin Storr; Birol Yüce; Burkhard Göke
[Perspectives of cannabinoids in gastroenterology].
Zeitschrift für Gastroenterologie 2006;44(2):185-91.
2006: Jörg Schirra; M Nicolaus; R Roggel; Martin Katschinski; Martin Storr; Hans-Juergen Woerle; Burkhard Göke
Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humans.
Gut 2006;55(2):243-51.
2006: Martin Storr; Burkhard Göke; A Wagner
An unusual cause of azathioprine inefficacy.
Endoscopy 2006;38 Suppl 2():E61.
2006: Martin Storr; Burkhard Göke; Helmut M Diepolder
An unusual cause of intractable vomiting after cisplatin chemotherapy.
Endoscopy 2006;38 Suppl 2():E54.
2006: Andrei Sibaev; B Yuece; Olaf Kelber; Dieter Weiser; Jörg Schirra; Burkhard Göke; Hans-Dieter Allescher; Martin Storr
STW 5 (Iberogast) and its individual herbal components modulate intestinal electrophysiology of mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2006;13 Suppl 5():80-9.
2006: Uli C Broedl; Michael Lehrke; Elisabeth Fleischer-Brielmaier; Anne B Tietz; Jutta M Nagel; Burkhard Göke; Peter Lohse; Klaus G Parhofer
Genetic variants of adiponectin receptor 2 are associated with increased adiponectin levels and decreased triglyceride/VLDL levels in patients with metabolic syndrome.
Cardiovascular diabetology 2006;5():11.
2006: Stephan Brand; Katrin Hofbauer; Julia Dambacher; Fabian Schnitzler; Tanja Staudinger; Simone Pfennig; Julia Seiderer; Cornelia Tillack; Astrid Konrad; Burkhard Göke; Thomas Ochsenkühn; Peter Lohse
Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype.
The American journal of gastroenterology 2006;101(1):99-106.
2006: S Unterholzner; Michael J Willhauck; Neziha Cengic; M Schütz; Burkhard Göke; John C Morris; Christine Spitzweg
Dexamethasone stimulation of retinoic Acid-induced sodium iodide symporter expression and cytotoxicity of 131-I in breast cancer cells.
The Journal of clinical endocrinology and metabolism 2006;91(1):69-78.
2005: Stephan Brand; Florian Beigel; Torsten Olszak; Kathrin Zitzmann; Sören Eichhorst; Jan-Michel Otte; Joachim Diebold; Helmut M Diepolder; Barbara Adler; Christoph J Auernhammer; Burkhard Göke; Julia Dambacher
IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(5):G960-8.
2005: Stephan Brand; Julia Dambacher; Florian Beigel; Torsten Olszak; Joachim Diebold; Jan-Michel Otte; Burkhard Göke; Sören Eichhorst
CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation.
Experimental cell research 2005;310(1):117-30.
2005: Julia Seiderer; Christoph J Zech; Walter Reinisch; Milan Lukas; Joachim Diebold; Fritz Wrba; Alexander Teml; Petra Chalupna; Jan Stritesky; Stefan O Schoenberg; Wolfgang Schima; Burkhard Göke; Thomas Ochsenkühn
A multicenter assessment of liver toxicity by MRI and biopsy in IBD patients on 6-thioguanine.
Journal of hepatology 2005;43(2):303-9.
2005: Neziha Cengic; Claire H Baker; Martin Schütz; Burkhard Göke; John C Morris; Christine Spitzweg
A novel therapeutic strategy for medullary thyroid cancer based on radioiodine therapy following tissue-specific sodium iodide symporter gene expression.
The Journal of clinical endocrinology and metabolism 2005;90(8):4457-64.
2005: Stephan Brand; Tanja Staudinger; Fabian Schnitzler; Simone Pfennig; Katrin Hofbauer; Julia Dambacher; Julia Seiderer; Cornelia Tillack; Astrid Konrad; Alexander Crispin; Burkhard Göke; Peter Lohse; Thomas Ochsenkühn
The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease.
Inflammatory bowel diseases 2005;11(7):645-52.
2005: Jörg Schirra; Burkhard Göke
The physiological role of GLP-1 in human: incretin, ileal brake or more?
Regulatory peptides 2005;128(2):109-15.
2005: Stephan Brand; Kathrin Zitzmann; Julia Dambacher; Florian Beigel; Torsten Olszak; George Vlotides; Sören Eichhorst; Burkhard Göke; Helmut M Diepolder; Christoph J Auernhammer
SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29.
Biochemical and biophysical research communications 2005;331(2):543-8.
2005: Eike Gallmeier; Claus Schäfer; P Moubarak; Anne Barbara Tietz; I Plössl; Ralf Huss; Burkhard Göke; Andreas C C Wagner
JAK and STAT proteins are expressed and activated by IFN-gamma in rat pancreatic acinar cells.
Journal of cellular physiology 2005;203(1):209-16.
2005: Bommer Guido; Claudia Jäger; Eva-Maria Dürr; Sebastian Baehs; Sören Eichhorst; Thomas Brabletz; Gang Hu; Thomas Fröhlich; Georg Arnold; Dagmar C Kress; Burkhard Göke; Guido Bommer; Frank T Kolligs
DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells.
The Journal of biological chemistry 2005;280(9):7962-75.
2005: Martin Storr; R Linke; M Nicolaus; Burkhard Göke; Jörg Schirra
[Injection of botulinum toxin for diffuse esophageal spasm].
Deutsche medizinische Wochenschrift (1946) 2005;130(6):266-9.
2005: Konstanze Lenhard; Bommer Guido; Silke Asutay; Rolf Schauer; Thomas Brabletz; Burkhard Göke; Rolf Lamerz; Frank T Kolligs
Analysis of promoter methylation in stool: a novel method for the detection of colorectal cancer.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(2):142-9.
2005: IV Scholz; Neziha Cengic; Claire H Baker; K J Harrington; Konstantin Maletz; Elizabeth R Bergert; R Vile; Burkhard Göke; John C Morris; Christine Spitzweg
Radioiodine therapy of colon cancer following tissue-specific sodium iodide symporter gene transfer.
Gene therapy 2005;12(3):272-80.
2005: Thomas Ochsenkühn; Ekkehard Bayerdörffer; Alexander Meining; Lydia Späth; Gerd Alexander Mannes; Baldur Wiebecke; Wolfgang Eiermann; Michael Sackmann; Burkhard Göke
Increased prevalence of colorectal adenomas in women with breast cancer.
Digestion 2005;72(2-3):150-5.
2005: Claus Schäfer; Anne Barbara Tietz; Burkhard Göke
Pathophysiology of acute experimental pancreatitis: lessons from genetically engineered animal models and new molecular approaches.
Digestion 2005;71(3):162-72.
2005: Klaus G Parhofer; Carsten Otto; H Christian Geiss; Ester Laubach; Burkhard Göke
Effect of pioglitazone on lipids in well controlled patients with diabetes mellitus type 2 -- results of a pilot study.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2005;113(1):49-52.
2004: Thomas Ochsenkühn; Michael Sackmann; Burkhard Göke
Infliximab for acute, not steroid-refractory ulcerative colitis: a randomized pilot study.
European journal of gastroenterology & hepatology 2004;16(11):1167-71.
2004: Thomas Ochsenkühn; Karin Herrmann; Stefan O Schoenberg; Maximilian F Reiser; Burkhard Göke; Michael Sackmann
Crohn disease of the small bowel proximal to the terminal ileum: detection by MR-enteroclysis.
Scandinavian journal of gastroenterology 2004;39(10):953-60.
2004: Constanze Kubisch; Matthew J DiMagno; Anne Barbara Tietz; Michael J Welsh; Stephen A Ernst; Barbara Brandt-Nedelev; Joachim Diebold; Andreas C C Wagner; Burkhard Göke; John Williams; Claus Schäfer
Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis.
Gastroenterology 2004;127(1):275-86.
2004: Astrid Konrad; Cordula Rütten; Beatrice Flogerzi; Maya Styner; Burkhard Göke; Frank Seibold
Immune sensitization to yeast antigens in ASCA-positive patients with Crohn's disease.
Inflammatory bowel diseases 2004;10(2):97-105.
2004: I Ploessl; Eike Gallmeier; C Schaefer; Manfred Bilzer; Iris Bittmann; Burkhard Göke; Andreas C C Wagner
ANP preconditioning does not increase protection against experimental pancreatitis, observed after general anesthesia and jugular vein catheterization.
Pancreas 2004;28(2):166-73.
2004: IV Scholz; Neziha Cengic; Burkhard Göke; John C Morris; Christine Spitzweg
Dexamethasone enhances the cytotoxic effect of radioiodine therapy in prostate cancer cells expressing the sodium iodide symporter.
The Journal of clinical endocrinology and metabolism 2004;89(3):1108-16.
2004: Burkhard Göke; Georg Lübben; P C Bates
Coefficient of beta-cell failure in patients with type 2 diabetes treated with pioglitazone or acarbose.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2004;112(2):115-7.
2004: Julia Seiderer; Burkhard Göke; Thomas Ochsenkühn
Safety aspects of infliximab in inflammatory bowel disease patients. A retrospective cohort study in 100 patients of a German University Hospital.
Digestion 2004;70(1):3-9.
2003: Gerald Ulrich Denk; Karl-Heinz Bergstermann; Eike Gallmeier; Jörg Schirra; Hubert Wagner; Burkhard Göke; Rolf Lamerz
[A 27-year-old patient with recurrent Fever].
Medizinische Klinik (Munich, Germany : 1983) 2003;98(11):641-5.
2003: Claus Schäfer; Hanna Steffen; Karen J Krzykowski; Burkhard Göke; Guy E Groblewski
CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(4):G726-34.
2003: Christine Spitzweg; IV Scholz; Elizabeth R Bergert; DJ Tindall; Charles Y F Young; Burkhard Göke; John C Morris
Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells.
Endocrinology 2003;144(8):3423-32.
2003: Christoph J Auernhammer; Dieter Engelhardt; Burkhard Göke
[Primary hyperparathyroidism, adrenal tumors and neuroendocrine tumors of the pancreas--clinical diagnosis and imaging requirements].
Der Radiologe 2003;43(4):265-74.
2003: Thomas Ochsenkühn; Igor Marsteller; Ulrich Hay; Joachim Diebold; Gustav Paumgartner; Burkhard Göke; Michael Sackmann
Does ursodeoxycholic acid change the proliferation of the colorectal mucosa?. A randomized, placebo-controlled study.
Digestion 2003;68(4):209-16.
2003: Nicolaus Holzknecht; Thomas Helmberger; Karin Herrmann; Thomas Ochsenkühn; Burkhard Göke; Maximilian Reiser
[MRI in Crohn's disease after transduodenal contrast administration using negative oral MRI contrast media].
Der Radiologe 2003;43(1):43-50.
2002: Alexandra Göke; Rüdiger Göke; Anja Knolle; Heidi Trusheim; Harald Schmidt; Andreas Wilmen; Ruaidhri Carmody; Burkhard Göke; Youhai H Chen
DUG is a novel homologue of translation initiation factor 4G that binds eIF4A.
Biochemical and biophysical research communications 2002;297(1):78-82.
2002: Thomas Ochsenkühn; Burkhard Göke; Michael Sackmann
Combining infliximab with 6-mercaptopurine/azathioprine for fistula therapy in Crohn's disease.
The American journal of gastroenterology 2002;97(8):2022-5.
2002: Klaus G Parhofer; Burkhard Göke
[Glinides and glitazones in diabetes treatment. Are they really effective?].
MMW Fortschritte der Medizin 2002;144(18):34-6, 38-9.
2002: A Thum; K Hupe-Sodmann; Rüdiger Göke; Karlheinz Voigt; Burkhard Göke; Gerard P McGregor
Endoproteolysis by isolated membrane peptidases reveal metabolic stability of glucagon-like peptide-1 analogs, exendins-3 and -4.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2002;110(3):113-8.
2002: Martin Gotthardt; Marc Fischer; Inga Naeher; Josefin B Holz; Hartmut Jungclas; Hans-Walter Fritsch; Martin Béhé; Burkhard Göke; Klaus Joseph; Thomas M Behr
Use of the incretin hormone glucagon-like peptide-1 (GLP-1) for the detection of insulinomas: initial experimental results.
European journal of nuclear medicine and molecular imaging 2002;29(5):597-606.
2002: Jürgen Meyer; Jeppe Sturis; Martin Katschinski; Rudolf Arnold; Burkhard Göke; Maria M Byrne
Acute hyperglycemia alters the ability of the normal beta-cell to sense and respond to glucose.
American journal of physiology. Endocrinology and metabolism 2002;282(4):E917-22.
2002: Jörg Schirra; U Wank; Rudolf Arnold; Burkhard Göke; Martin Katschinski
Effects of glucagon-like peptide-1(7-36)amide on motility and sensation of the proximal stomach in humans.
Gut 2002;50(3):341-8.
2002: Burkhard Göke
Improved glycemic control and lipid profile in a randomized study of pioglitazone compared with acarbose in patients with type 2 diabetes mellitus.
Treatments in endocrinology 2002;1(5):329-36.
2002: Stefanie Hagner; Jens Knauer; Rainer V Haberberger; Burkhard Göke; Karlheinz Voigt; Gerard P McGregor
Calcitonin receptor-like receptor is expressed on gastrointestinal immune cells.
Digestion 2002;66(4):197-203.
2002: Frank T Kolligs; Bommer Guido; Burkhard Göke
Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.
Digestion 2002;66(3):131-44.
2002: Burkhard Göke; Bernhard Hoppe; Astrid Konrad; Jörg Schirra
[A therapeutic option for type-2 diabetes. The incretion hormone GLP-1].
Pharmazie in unserer Zeit 2002;31(3):294-9.
2002: Carsten Otto; Michael Lehrke; Burkhard Göke
Novel insulin sensitizers: pharmacogenomic aspects.
Pharmacogenomics 2002;3(1):99-116.
2001: Wolfgang Hempfling; Christian Rust; Michael Sackmann; G U Müller-Lisse; Helmut Arbogast; Dieter Jüngst; Burkhard Göke
[75-year-old patient with persistent abdominal complaints and vomiting during a cruise].
Medizinische Klinik (Munich, Germany : 1983) 2001;96(12):735-9.
2001: A Trümper; Katja Trümper; Heidi Trusheim; Rudolf Arnold; Burkhard Göke; Dieter Hörsch
Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling.
Molecular endocrinology (Baltimore, Md.) 2001;15(9):1559-70.
2001: R Pfammatter; C Quattropani; J Reichen; Burkhard Göke; Andreas C C Wagner
Treatment of hepatic hydrothorax and reduction of chest tube output with octreotide.
European journal of gastroenterology & hepatology 2001;13(8):977-80.
2001: A Brandt; Martin Katschinski; Rudolf Arnold; Kenneth S Polonsky; Burkhard Göke; Maria M Byrne
GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve.
American journal of physiology. Endocrinology and metabolism 2001;281(2):E242-7.
2001: F Fleischer; R Dabew; Burkhard Göke; Andreas C C Wagner
Stress kinase inhibition modulates acute experimental pancreatitis.
World journal of gastroenterology : WJG 2001;7(2):259-65.
2001: M Steinhoff; H Hesse; Burkhard Göke; A Steinhoff; Rolf Eissele; E P Slater
Indirect RT-PCR in-situ hybridization: a novel non-radioactive method for detecting glucose-dependent insulinotropic peptide.
Regulatory peptides 2001;97(2-3):187-94.
2001: Stefanie Hagner; Rainer V Haberberger; Wolfgang Kummer; Jochen Springer; A Fischer; S Böhm; Burkhard Göke; Gerard P McGregor
Immunohistochemical detection of calcitonin gene-related peptide receptor (CGRPR)-1 in the endothelium of human coronary artery and bronchial blood vessels.
Neuropeptides 2001;35(1):58-64.
2001: Rüdiger Göke; Alexandra Göke; Burkhard Göke; Wafik S El-Deiry; Youhai Chen
Pioglitazone inhibits growth of carcinoid cells and promotes TRAIL-induced apoptosis by induction of p21waf1/cip1.
Digestion 2001;64(2):75-80.
2001: Maria M Byrne; G P McGregor; P Barth; M Rothmund; Burkhard Göke; Rudolf Arnold
Intestinal proliferation and delayed intestinal transit in a patient with a GLP-1-, GLP-2- and PYY-producing neuroendocrine carcinoma.
Digestion 2001;63(1):61-8.
2000: Heike Weber; Andreas C C Wagner; Ludwig Jonas; Jutta Merkord; T Höfken; Horst Nizze; P Leitzmann; Burkhard Göke; Peter Schuff-Werner
Heat shock response is associated with protection against acute interstitial pancreatitis in rats.
Digestive diseases and sciences 2000;45(11):2252-64.
2000: T Höfken; N Keller; F Fleischer; Burkhard Göke; Andreas C C Wagner
Map kinase phosphatases (MKP's) are early responsive genes during induction of cerulein hyperstimulation pancreatitis.
Biochemical and biophysical research communications 2000;276(2):680-5.
2000: F S Galehshahi; Burkhard Göke; Brigitte Lankat-Buttgereit
A novel silencer element repressing expression of the GLP-1 receptor gene in fibroblasts and pancreatic A-cells, but not in pancreatic B- and D-cells.
Peptides 2000;21(8):1169-76.
2000: Rüdiger Göke; Alexandra Göke; Burkhard Göke; Youhai Chen
Regulation of TRAIL-induced apoptosis by transcription factors.
Cellular immunology 2000;201(2):77-82.
2000: Jörg Schirra; P Houck; U Wank; Rudolf Arnold; Burkhard Göke; Martin Katschinski
Effects of glucagon-like peptide-1(7-36)amide on antro-pyloro-duodenal motility in the interdigestive state and with duodenal lipid perfusion in humans.
Gut 2000;46(5):622-31.
2000: C Herrmann-Rinke; Gerard P McGregor; Burkhard Göke
Calcitonin gene-related peptide potently stimulates glucagon-like peptide-1 release in the isolated perfused rat ileum.
Peptides 2000;21(3):431-7.
2000: Hasan Kulaksiz; Rudolf Arnold; Burkhard Göke; Erik Maronde; M Meyer; F Fahrenholz; W G Forssmann; Rolf Eissele
Expression and cell-specific localization of the cholecystokinin B/gastrin receptor in the human stomach.
Cell and tissue research 2000;299(2):289-98.
2000: Katja Trümper; A Trümper; Heidi Trusheim; Rudolf Arnold; Burkhard Göke; Dieter Hörsch
Integrative mitogenic role of protein kinase B/Akt in beta-cells.
Annals of the New York Academy of Sciences 2000;921():242-50.
2000: Andreas C C Wagner; Luca Mazzucchelli; M Miller; A M Camoratto; Burkhard Göke
CEP-1347 inhibits caerulein-induced rat pancreatic JNK activation and ameliorates caerulein pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(1):G165-72.
1999: F A Ozdemir; P Berghöfer; Rüdiger Göke; Burkhard Göke; Gerard P McGregor
Specific calcitonin gene-related peptide binding sites present throughout rat intestine.
Peptides 1999;20(11):1361-6.
1999: Hans-Peter Bode; B Moormann; R Dabew; Burkhard Göke
Glucagon-like peptide 1 elevates cytosolic calcium in pancreatic beta-cells independently of protein kinase A.
Endocrinology 1999;140(9):3919-27.
1999: W Metzler; T Höfken; Heike Weber; Hartmut Printz; Burkhard Göke; Andreas C C Wagner
Hyperthermia, inducing pancreatic heat-shock proteins, fails to prevent cerulein-induced stress kinase activation.
Pancreas 1999;19(2):150-7.
1999: I Wildhage; Heidi Trusheim; Burkhard Göke; Brigitte Lankat-Buttgereit
Gene expression of the human glucagon-like peptide-1 receptor is regulated by Sp1 and Sp3.
Endocrinology 1999;140(2):624-31.
1999: Hans-Peter Bode; S Weber; Hans-Christoph Fehmann; Burkhard Göke
A nutrient-regulated cytosolic calcium oscillator in endocrine pancreatic glucagon-secreting cells.
Pflügers Archiv : European journal of physiology 1999;437(3):324-34.
1999: Andreas C C Wagner; W Metzler; T Höfken; Heike Weber; Burkhard Göke
p38 map kinase is expressed in the pancreas and is immediately activated following cerulein hyperstimulation.
Digestion 1999;60(1):41-7.
1998: Ulrich Wulbrand; Matthias U Wied; P Zöfel; Burkhard Göke; Rudolf Arnold; Hans-Christoph Fehmann
Growth factor receptor expression in human gastroenteropancreatic neuroendocrine tumours.
European journal of clinical investigation 1998;28(12):1038-49.
1998: Hartmut Printz; S Reiter; Nader Samadi; Schokufe Ebrahimsade; R Kirchner; Rudolf Arnold; Burkhard Göke
GLP-1 release in man after lower large bowel resection or intrarectal glucose administration.
Digestion 1998;59(6):689-95.
1998: T Höfken; D Linder; Ralf Kleene; Burkhard Göke; Andreas C C Wagner
Membrane dipeptidase and glutathione are major components of pig pancreatic zymogen granules.
Experimental cell research 1998;244(2):481-90.
1998: F S Galehshahi; Burkhard Göke; Brigitte Lankat-Buttgereit
Contribution of a PS1-like element to the tissue- and cell-specific expression of the human GLP-1 receptor gene.
FEBS letters 1998;436(2):163-8.
1998: Hans-Christoph Fehmann; A Pracht; Burkhard Göke
High-level expression of the GLP-I receptor results in receptor desensitization.
Pancreas 1998;17(3):309-14.
1998: Burkhard Göke; C Herrmann-Rinke
The evolving role of alpha-glucosidase inhibitors.
Diabetes/metabolism reviews 1998;14 Suppl 1():S31-8.
1998: Maria M Byrne; K Gliem; U Wank; Rudolf Arnold; Martin Katschinski; Kenneth S Polonsky; Burkhard Göke
Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance.
Diabetes 1998;47(8):1259-65.
1998: Babette Simon; D Bartsch; Peter Barth; N Prasnikar; Karin Münch; A Blum; Rudolf Arnold; Burkhard Göke
Frequent abnormalities of the putative tumor suppressor gene FHIT at 3p14.2 in pancreatic carcinoma cell lines.
Cancer research 1998;58(8):1583-7.
1998: Jörg Schirra; K Sturm; P Leicht; Rudolf Arnold; Burkhard Göke; Martin Katschinski
Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humans.
The Journal of clinical investigation 1998;101(7):1421-30.
1998: Hartmut Printz; Burkhard Göke
[Conservative and interventional therapy of acute diverticulitis with reference to pathophysiology].
Zentralblatt für Chirurgie 1998;123(12):1375-81.
1998: Andreas Wilmen; A Walkenbach; P Füller; Brigitte Lankat-Buttgereit; Rüdiger Göke; Burkhard Göke
The genomic organization of the human GLP-1 receptor gene.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1998;106(4):299-302.
1998: Gerard P McGregor; Rüdiger Göke; Burkhard Göke
Biological actions of glucagon-like peptide(GLP)-2 revealed--how pluripotential is the glucagon gene?
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1998;106(1):25-8.
1998: Maria M Byrne; K Pluntke; U Wank; Jörg Schirra; Rudolf Arnold; Burkhard Göke; Martin Katschinski
Inhibitory effects of hyperglycaemia on fed jejunal motility: potential role of hyperinsulinaemia.
European journal of clinical investigation 1998;28(1):72-8.
1998: Jörg Schirra; P Leicht; P Hildebrand; C Beglinger; Rudolf Arnold; Burkhard Göke; Martin Katschinski
Mechanisms of the antidiabetic action of subcutaneous glucagon-like peptide-1(7-36)amide in non-insulin dependent diabetes mellitus.
The Journal of endocrinology 1998;156(1):177-86.
1997: Hans-Christoph Fehmann; P Berghöfer; D Brandhorst; H Brandhorst; B Hering; R G Bretzel; Burkhard Göke
Leptin inhibition of insulin secretion from isolated human islets.
Acta diabetologica 1997;34(4):249-52.
1997: Hans-Christoph Fehmann; Hans-Peter Bode; T Ebert; Alexander Karl; Burkhard Göke
Interaction of GLP-I and leptin at rat pancreatic B-cells: effects on insulin secretion and signal transduction.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1997;29(11):572-6.
1997: A Hareter; E Hoffmann; Hans-Peter Bode; Burkhard Göke; Rüdiger Göke
The positive charge of the imidazole side chain of histidine7 is crucial for GLP-1 action.
Endocrine journal 1997;44(5):701-5.
1997: M Z Strowski; Gisela Sparmann; Heike Weber; F Fiedler; Hartmut Printz; Ludwig Jonas; Burkhard Göke; Andreas C C Wagner
Caerulein pancreatitis increases mRNA but reduces protein levels of rat pancreatic heat shock proteins.
The American journal of physiology 1997;273(4 Pt 1):G937-45.
1997: Martin Katschinski; Jörg Schirra; A Bross; Burkhard Göke; Rudolf Arnold
Duodenal secretion and fecal excretion of pancreatic elastase-1 in healthy humans and patients with chronic pancreatitis.
Pancreas 1997;15(2):191-200.
1997: Hans-Christoph Fehmann; Burkhard Göke
[Intestinal cell proliferation, acromegaly and colon tumors].
Zeitschrift für Gastroenterologie 1997;35(4):305-6.
1997: Burkhard Göke; Hans-Christoph Fehmann; Jörg Schirra; A Hareter; Rüdiger Göke
[The intestinal hormone glucagon-like peptide 1 (GLP-1): from experiment to the clinic].
Zeitschrift für Gastroenterologie 1997;35(4):285-94.
1997: Dieter Hörsch; Rüdiger Göke; Rolf Eissele; B Michel; Burkhard Göke
Reciprocal cellular distribution of glucagon-like peptide-1 (GLP-1) immunoreactivity and GLP-1 receptor mRNA in pancreatic islets of rat.
Pancreas 1997;14(3):290-4.
1997: P Berghöfer; R G Peterson; K Schneider; Hans-Christoph Fehmann; Burkhard Göke
Incretin hormone expression in the gut of diabetic mice and rats.
Metabolism: clinical and experimental 1997;46(3):261-7.
1997: Hans-Christoph Fehmann; Christian Peiser; Hans-Peter Bode; M Stamm; Petra Staats; C Hedetoft; Rudolf Ernst Lang; Burkhard Göke
Leptin: a potent inhibitor of insulin secretion.
Peptides 1997;18(8):1267-73.
1997: Hartmut Printz; R Schlenzka; P Requadt; M Tscherny; Andreas C C Wagner; Rolf Eissele; Matthias Rothmund; Rudolf Arnold; Burkhard Göke
Small bowel lengthening by mechanical distraction.
Digestion 1997;58(3):240-8.
1997: Hartmut Printz; B Recke; Hans-Christoph Fehmann; Burkhard Göke
No apparent benefit of liquid formula diet in NIDDM.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1997;105(3):134-9.
1997: Burkhard Göke
Gene level diagnostics in gastroenterology.
Digestion 1997;58 Suppl 1():82-5.
1997: K Hupe-Sodmann; Rüdiger Göke; Burkhard Göke; H H Thole; B Zimmermann; Karlheinz Voigt; Gerard P McGregor
Endoproteolysis of glucagon-like peptide (GLP)-1 (7-36) amide by ectopeptidases in RINm5F cells.
Peptides 1997;18(5):625-32.
1997: Brigitte Lankat-Buttgereit; Burkhard Göke
Cloning and characterization of the 5' flanking sequences (promoter region) of the human GLP-1 receptor gene.
Peptides 1997;18(5):617-24.
1997: Andreas Wilmen; B Van Eyll; Burkhard Göke; Rüdiger Göke
Five out of six tryptophan residues in the N-terminal extracellular domain of the rat GLP-1 receptor are essential for its ability to bind GLP-1.
Peptides 1997;18(2):301-5.
1997: Jörg Schirra; P Kuwert; U Wank; P Leicht; Rudolf Arnold; Burkhard Göke; Martin Katschinski
Differential effects of subcutaneous GLP-1 on gastric emptying, antroduodenal motility, and pancreatic function in men.
Proceedings of the Association of American Physicians 1997;109(1):84-97.
1996: Andreas Wilmen; Burkhard Göke; Rüdiger Göke
The isolated N-terminal extracellular domain of the glucagon-like peptide-1 (GLP)-1 receptor has intrinsic binding activity.
FEBS letters 1996;398(1):43-7.
1996: Andreas C C Wagner; Heike Weber; Ludwig Jonas; Horst Nizze; M Strowski; F Fiedler; Hartmut Printz; H Steffen; Burkhard Göke
Hyperthermia induces heat shock protein expression and protection against cerulein-induced pancreatitis in rats.
Gastroenterology 1996;111(5):1333-42.
1996: Maria M Byrne; Burkhard Göke
Human studies with glucagon-like-peptide-1: potential of the gut hormone for clinical use.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(10):854-60.
1996: Hans-Christoph Fehmann; J Jiang; D Pitt; J Schweinfurth; Burkhard Göke
Ligand-induced regulation of glucagon-like peptide-I receptor function and expression in insulin-secreting beta cells.
Pancreas 1996;13(3):273-82.
1996: Burkhard Göke; H Steffen; Rüdiger Göke
The signal transduction of the glucagon-like peptide 1 receptor: fishing beyond the protein kinase level.
Acta physiologica Scandinavica 1996;157(3):321-8.
1996: Hans-Christoph Fehmann; P Jehle; U Markus; Burkhard Göke
Functional active receptors for insulin-like growth factors-I (IGF-I) and IGF-II on insulin-, glucagon-, and somatostatin-producing cells.
Metabolism: clinical and experimental 1996;45(6):759-66.
1996: Hans-Christoph Fehmann; J Schweinfurth; J Jiang; Burkhard Göke
Regulation of glucagon-like peptide-I receptor expression and transcription by the protein kinase C pathway.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1996;196(4):219-25.
1996: C Herrmann-Rinke; Rolf Eissele; Rudolf Arnold; Burkhard Göke
Studies on the viability of the isolated vascularly perfused rat colon.
Digestion 1996;57(5):349-55.
1996: C Herrmann-Rinke; Dieter Hörsch; Gerard P McGregor; Burkhard Göke
Galanin is a potent inhibitor of glucagon-like peptide-1 secretion from rat ileum.
Peptides 1996;17(4):571-6.
1996: B Van Eyll; Burkhard Göke; Andreas Wilmen; Rüdiger Göke
Exchange of W39 by A within the N-terminal extracellular domain of the GLP-1 receptor results in a loss of receptor function.
Peptides 1996;17(4):565-70.
1996: Jörg Schirra; Martin Katschinski; C Weidmann; T Schäfer; U Wank; Rudolf Arnold; Burkhard Göke
Gastric emptying and release of incretin hormones after glucose ingestion in humans.
The Journal of clinical investigation 1996;97(1):92-103.
1995: A Volz; Rüdiger Göke; Brigitte Lankat-Buttgereit; Hans-Christoph Fehmann; Hans-Peter Bode; Burkhard Göke
Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma.
FEBS letters 1995;373(1):23-9.
1995: Hans-Christoph Fehmann; M Janssen; Burkhard Göke
Interaction of glucagon-like peptide-I (GLP-I) and galanin in insulin (beta TC-1)- and somatostatin (RIN T3)-secreting cells and evidence that both peptides have no receptors on glucagon (INR1G9)-secreting cells.
Acta diabetologica 1995;32(3):176-81.
1995: C Herrmann-Rinke; A Vöge; M Hess; Burkhard Göke
Regulation of glucagon-like peptide-1 secretion from rat ileum by neurotransmitters and peptides.
The Journal of endocrinology 1995;147(1):25-31.
1995: Hans-Christoph Fehmann; Burkhard Göke
[Amylin: from humans and mice].
Zeitschrift für Gastroenterologie 1995;33(9):551-2.
1995: K Hupe-Sodmann; Gerard P McGregor; R Bridenbaugh; Rüdiger Göke; Burkhard Göke; H Thole; B Zimmermann; Karlheinz Voigt
Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides.
Regulatory peptides 1995;58(3):149-56.
1995: Hans-Christoph Fehmann; B J Hering; M J Wolf; H Brandhorst; D Brandhorst; R G Bretzel; K Federlin; Burkhard Göke
The effects of glucagon-like peptide-I (GLP-I) on hormone secretion from isolated human pancreatic islets.
Pancreas 1995;11(2):196-200.
1995: Roberto Gherzi; Hans-Christoph Fehmann; A Volz; Marco Ponassi; Burkhard Göke
The glucagon gene is transcribed in beta-like pancreatic cells.
Experimental cell research 1995;218(2):460-8.
1995: Hans-Christoph Fehmann; Rüdiger Göke; Burkhard Göke
Cell and molecular biology of the incretin hormones glucagon-like peptide-I and glucose-dependent insulin releasing polypeptide.
Endocrine reviews 1995;16(3):390-410.
1995: Burkhard Göke; Rüdiger Göke; Hans-Christoph Fehmann; Rudolf Arnold
[Incretin research in the development of new strategies of diabetes therapy].
Der Internist 1995;36(4):343-9.
1995: Hartmut Printz; H Siegmund; C Wojte; C Schäfer; H Hesse; Matthias Rothmund; Burkhard Göke
"Human pancreas-specific protein" (procarboxypeptidase B): a valuable marker in pancreatitis?
Pancreas 1995;10(3):222-30.
1995: Andreas C C Wagner; M Z Strowski; Burkhard Göke; John Williams
Molecular cloning of a new member of the Rab protein family, Rab 26, from rat pancreas.
Biochemical and biophysical research communications 1995;207(3):950-6.
1995: Hans-Christoph Fehmann; Roberto Gherzi; Burkhard Göke
Regulation of islet hormone gene expression by incretin hormones.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1995;103 Suppl 2():56-65.
1995: Hans-Christoph Fehmann; P Jehle; Burkhard Göke
IGF-I and IGF-II: expression and function in the endocrine pancreas.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1995;103 Suppl 2():37-41.
1995: Burkhard Göke; H Fuder; G Wieckhorst; U Theiss; E Stridde; T Littke; P Kleist; Rudolf Arnold; Peter Wolfgang Lücker
Voglibose (AO-128) is an efficient alpha-glucosidase inhibitor and mobilizes the endogenous GLP-1 reserve.
Digestion 1995;56(6):493-501.
1995: Hans-Christoph Fehmann; Burkhard Göke
Characterization of GIP(1-30) and GIP(1-42) as stimulators of proinsulin gene transcription.
Peptides 1995;16(6):1149-52.
1995: Hans-Christoph Fehmann; Burkhard Göke
[7B2--the first neuroendocrine chaperone].
Zeitschrift für Gastroenterologie 1995;33(1):24-5.
1995: Hans-Christoph Fehmann; M Strowski; Burkhard Göke
Functional characterization of somatostatin receptors expressed on hamster glucagonoma cells.
The American journal of physiology 1995;268(1 Pt 1):E40-7.
1995: F Kolligs; Hans-Christoph Fehmann; Rüdiger Göke; Burkhard Göke
Reduction of the incretin effect in rats by the glucagon-like peptide 1 receptor antagonist exendin (9-39) amide.
Diabetes 1995;44(1):16-9.
1995: C Herrmann; Rüdiger Göke; G Richter; Hans-Christoph Fehmann; Rudolf Arnold; Burkhard Göke
Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients.
Digestion 1995;56(2):117-26.
1994: Hans-Peter Bode; D I Yule; Hans-Christoph Fehmann; Burkhard Göke; John Williams
Spontaneous calcium oscillations in clonal endocrine pancreatic glucagon-secreting cells.
Biochemical and biophysical research communications 1994;205(1):435-40.
1994: Roberto Gherzi; Paola Briata; Hans-Christoph Fehmann; Burkhard Göke
Ras antagonizes cAMP stimulated glucagon gene transcription in pancreatic islet cell lines.
FEBS letters 1994;353(3):277-80.
1994: Matthew J Wishart; GE Groblewski; Burkhard Göke; Andreas C C Wagner; John Williams
Secretagogue regulation of pancreatic acinar cell protein phosphorylation shown by large-scale 2D-PAGE.
The American journal of physiology 1994;267(4 Pt 1):G676-86.
1994: C Schäfer; H Steffen; Hartmut Printz; Burkhard Göke
Effects of synthetic cyclic AMP analogs on amylase exocytosis from rat pancreatic acini.
Canadian journal of physiology and pharmacology 1994;72(10):1138-47.
1994: Burkhard Göke; C Herrmann; Rüdiger Göke; Hans-Christoph Fehmann; P Berghöfer; G Richter; Rudolf Arnold
Intestinal effects of alpha-glucosidase inhibitors: absorption of nutrients and enterohormonal changes.
European journal of clinical investigation 1994;24 Suppl 3():25-30.
1994: B van Eyll; Brigitte Lankat-Buttgereit; Hans-Peter Bode; Rüdiger Göke; Burkhard Göke
Signal transduction of the GLP-1-receptor cloned from a human insulinoma.
FEBS letters 1994;348(1):7-13.
1994: Hans-Christoph Fehmann; Burkhard Göke
[One gene--four diseases: on the importance of mutations in the ret gene in MEN 2A, MEN 2B, Hirschsprung disease and medullary thyroid carcinoma].
Zeitschrift für Gastroenterologie 1994;32(7):416-7.
1994: Brigitte Lankat-Buttgereit; Hans-Christoph Fehmann; B J Hering; R G Bretzel; Burkhard Göke
Expression of the ras-related rab3a gene in human insulinomas and normal human pancreatic islets.
Pancreas 1994;9(4):434-8.
1994: Roberto Gherzi; Hans-Christoph Fehmann; Rolf Eissele; Burkhard Göke
Expression, intracellular localization, and gene transcription regulation of the secretory protein 7B2 in endocrine pancreatic cell lines and human insulinomas.
Experimental cell research 1994;213(1):20-7.
1994: Rolf Eissele; Rüdiger Göke; U Weichardt; Hans-Christoph Fehmann; Rudolf Arnold; Burkhard Göke
Glucagon-like peptide 1 immunoreactivity in gastroentero-pancreatic endocrine tumors: a light- and electron-microscopic study.
Cell and tissue research 1994;276(3):571-9.
1994: Hans-Christoph Fehmann; M Strowski; Burkhard Göke
Interaction of glucagon-like peptide-I (7-37) and somatostatin-14 on signal transduction and proinsulin gene expression in beta TC-1 cells.
Metabolism: clinical and experimental 1994;43(6):787-92.
1994: Hans-Christoph Fehmann; J Jiang; J Schweinfurth; K Dörsch; M B Wheeler; A E Boyd; Burkhard Göke
Ligand-specificity of the rat GLP-I receptor recombinantly expressed in Chinese hamster ovary (CHO-) cells.
Zeitschrift für Gastroenterologie 1994;32(4):203-7.
1994: Hans-Peter Bode; Burkhard Göke
Protein kinase C activates capacitative calcium entry in the insulin secreting cell line RINm5F.
FEBS letters 1994;339(3):307-11.
1994: Brigitte Lankat-Buttgereit; Rüdiger Göke; Fritz Stöckmann; J Jiang; Hans-Christoph Fehmann; Burkhard Göke
Detection of the human glucagon-like peptide 1(7-36) amide receptor on insulinoma-derived cell membranes.
Digestion 1994;55(1):29-33.
1994: Rüdiger Göke; R Just; Brigitte Lankat-Buttgereit; Burkhard Göke
Glycosylation of the GLP-1 receptor is a prerequisite for regular receptor function.
Peptides 1994;15(4):675-81.
1994: Hans-Christoph Fehmann; J Jiang; J Schweinfurth; M B Wheeler; A E Boyd; Burkhard Göke
Stable expression of the rat GLP-I receptor in CHO cells: activation and binding characteristics utilizing GLP-I(7-36)-amide, oxyntomodulin, exendin-4, and exendin(9-39).
Peptides 1994;15(3):453-6.
1994: Rolf Eissele; E Bothe-Sandfort; Burkhard Göke; J Eng; Rudolf Arnold; H Koop
Rat gastric somatostatin and gastrin release: interactions of exendin-4 and truncated glucagon-like peptide-1 (GLP-1) amide.
Life sciences 1994;55(8):629-34.
1994: Brigitte Lankat-Buttgereit; Rüdiger Göke; Hans-Christoph Fehmann; G Richter; Burkhard Göke
Molecular cloning of a cDNA encoding for the GLP-1 receptor expressed in rat lung.
Experimental and clinical endocrinology 1994;102(4):341-7.
1994: Rainer Seitz; F Leugner; Martin Katschinski; A Immel; M Kraus; R Egbring; Burkhard Göke
Ulcerative colitis and Crohn's disease: factor XIII, inflammation and haemostasis.
Digestion 1994;55(6):361-7.
1994: Hans-Christoph Fehmann; M Strowski; Brigitte Lankat-Buttgereit; Burkhard Göke
Molecular and functional characterization of insulin receptors present on hamster glucagonoma cells.
Digestion 1994;55(4):214-20.
1993: G Richter; O Feddersen; Ulrich Wagner; P Barth; Rüdiger Göke; Burkhard Göke
GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery.
The American journal of physiology 1993;265(4 Pt 1):L374-81.
1993: Rüdiger Göke; Hans-Christoph Fehmann; T Linn; H Schmidt; M Krause; J Eng; Burkhard Göke
Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.
The Journal of biological chemistry 1993;268(26):19650-5.
1993: Gerard P McGregor; C Fehmann; R Hartel; K H Voigt; Burkhard Göke; Rüdiger Göke
Investigations of the expression and post-translational processing of the preprotachykinin-I (PPT-I) gene by rat pancreatic, insulin-producing tumor cell-lines.
Regulatory peptides 1993;46(1-2):444-6.
1993: Hans-Christoph Fehmann; Rüdiger Göke; Burkhard Göke
[Isolation and sequencing of cDNA of the GLP-I receptor].
Zeitschrift für Gastroenterologie 1993;31(3):218-9.
1993: Hartmut Printz; Burkhard Göke; Hans-Christoph Fehmann; S Weiershausen; R Nustede; M Neurath; Matthias Rothmund
Partial hepatectomy affects pancreatic size and function in rats.
Pancreas 1993;8(2):233-9.
1993: Rüdiger Göke; F Kolligs; G Richter; Brigitte Lankat-Buttgereit; Burkhard Göke
Solubilization of active receptors for glucagon-like peptide-1(7-36)amide from rat lung membranes.
The American journal of physiology 1993;264(2 Pt 1):L146-52.
1993: Rüdiger Göke; B Wagner; Hans-Christoph Fehmann; Burkhard Göke
Glucose-dependency of the insulin stimulatory effect of glucagon-like peptide-1 (7-36) amide on the rat pancreas.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1993;193(2):97-103.
1993: Ulrich Wagner; Hans-Christoph Fehmann; D Bredenböker; F Yu; Peter J Barth; Peter von Wichert; Burkhard Göke
The stimulatory effect of amylin on mucus secretion in isolated rat trachea.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1993;193(6):347-52.
1993: Rüdiger Göke; Gerard P McGregor; Burkhard Göke
Amylin alters the biological action of the incretin hormone GLP-1(7-36)amide.
Life sciences 1993;53(17):1367-72.
1992: B Noll; Burkhard Göke; B Simon; Bernhard Maisch
Cardiac natriuretic peptide hormones during artificial cardiac pacemaker stimulation and left heart catheterization.
The Clinical investigator 1992;70(12):1057-60.
1992: Gerard P McGregor; R Hartel; Hans-Christoph Fehmann; Brigitte Lankat-Buttgereit; Burkhard Göke; Rüdiger Göke; Karlheinz Voigt
Characterisation of the expression and post-translational processing of the preprotachykinin-I gene and the regulated release of tachykinins by the RINm5F cell-line.
FEBS letters 1992;312(2-3):187-91.
1992: Brigitte Lankat-Buttgereit; Rüdiger Göke; Hans-Christoph Fehmann; C Niess; Burkhard Göke
Expression of the ras-related rab3a gene in insulinoma-derived cell lines.
FEBS letters 1992;312(2-3):183-6.
1992: Hans-Christoph Fehmann; Burkhard Göke
[Cloning of secretin, VIP and somatostatin receptor cDNA's].
Zeitschrift für Gastroenterologie 1992;30(7):498-9.
1992: Hans-Christoph Fehmann; Rüdiger Göke; Burkhard Göke
Glucagon-like peptide-1(7-37)/(7-36)amide is a new incretin.
Molecular and cellular endocrinology 1992;85(1-2):C39-44.
1992: Rüdiger Göke; B Oltmer; Søren P Sheikh; Burkhard Göke
Solubilization of active GLP-1 (7-36)amide receptors from RINm5F plasma membranes.
FEBS letters 1992;300(3):232-6.
1992: Burkhard Göke; Volker Keim
HPLC and FPLC. Recent progress in the use of automated chromatography systems for resolution of pancreatic secretory proteins.
International journal of pancreatology : official journal of the International Association of Pancreatology 1992;11(2):109-16.
1992: Rolf Eissele; Rüdiger Göke; S Willemer; H P Harthus; H Vermeer; Rudolf Arnold; Burkhard Göke
Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man.
European journal of clinical investigation 1992;22(4):283-91.
1992: Burkhard Göke; John Williams; Matthew J Wishart; R C De Lisle
Low molecular mass GTP-binding proteins in subcellular fractions of the pancreas: regulated phosphoryl G proteins.
The American journal of physiology 1992;262(2 Pt 1):C493-500.
1992: Hans-Christoph Fehmann; Burkhard Göke
[Identification of the gene responsible for familial polyposis coli].
Zeitschrift für Gastroenterologie 1992;30(1):41-2.
1991: W Y Zhu; Burkhard Göke; John Williams
Binding, internalization, and processing of bombesin by rat pancreatic acini.
The American journal of physiology 1991;261(1 Pt 1):G57-64.
1991: Rüdiger Göke; Burkhard Göke
Analysis of low molecular mass GTP-binding proteins in insulinoma-derived RINm5F cells by two-dimensional gel electrophoresis.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1991;23(6):304-5.
1991: T Matozaki; W Y Zhu; Yasuhiro Tsunoda; Burkhard Göke; John Williams
Intracellular mediators of bombesin action on rat pancreatic acinar cells.
The American journal of physiology 1991;260(6 Pt 1):G858-64.
1991: Hans-Christoph Fehmann; Rüdiger Göke; Burkhard Göke; Rolf Eissele; Rudolf Arnold
Helodermin and islet hormone release in isolated rat pancreas.
International journal of pancreatology : official journal of the International Association of Pancreatology 1991;8(4):289-303.
1991: Rüdiger Göke; Hans-Christoph Fehmann; Burkhard Göke
Glucagon-like peptide-1(7-36) amide is a new incretin/enterogastrone candidate.
European journal of clinical investigation 1991;21(2):135-44.
1991: G Richter; Rüdiger Göke; Burkhard Göke; H Schmidt; Rudolf Arnold
Characterization of glucagon-like peptide-I(7-36)amide receptors of rat lung membranes by covalent cross-linking.
FEBS letters 1991;280(2):247-50.
1991: Hans-Christoph Fehmann; Rüdiger Göke; Burkhard Göke; R Bächle; B Wagner; Rudolf Arnold
Priming effect of glucagon-like peptide-1 (7-36) amide, glucose-dependent insulinotropic polypeptide and cholecystokinin-8 at the isolated perfused rat pancreas.
Biochimica et biophysica acta 1991;1091(3):356-63.
1990: Hans-Christoph Fehmann; G McGregor; V Weber; Rolf Eissele; Rüdiger Göke; Burkhard Göke; Rudolf Arnold
The effects of two FMRFamide related peptides (A-18-F-amide and F-8-F-amide; 'morphine modulating peptides') on the endocrine and exocrine rat pancreas.
Neuropeptides 1990;17(2):87-92.
1990: G Richter; Rüdiger Göke; Burkhard Göke; Rudolf Arnold
Dexamethasone pretreatment of rat insulinoma cells decreases binding of glucagon-like peptide-1(7-36)amide.
The Journal of endocrinology 1990;126(3):445-50.
1990: Hartmut Printz; B Emmerich; H Loth; Burkhard Göke
Protein profiles in rabbit pancreatic juice analyzed by HPLC after stimulation of secretion by secretin and cerulein.
Zeitschrift für Gastroenterologie 1990;28(8):383-8.
1990: B Noll; J Krappe; Burkhard Göke; Bernhard Maisch
Atrial natriuretic peptide levels reflect hemodynamic changes under pacemaker stimulation.
Pacing and clinical electrophysiology : PACE 1990;13(8):970-5.
1990: G Richter; Rüdiger Göke; Burkhard Göke; Rudolf Arnold
Characterization of receptors for glucagon-like peptide-1(7-36)amide on rat lung membranes.
FEBS letters 1990;267(1):78-80.
1990: Hans-Christoph Fehmann; Rüdiger Göke; Burkhard Göke; Rudolf Arnold
Carbachol priming increases glucose- and glucagon-like peptide-1 (7-36)amide-, but not arginine-induced insulin secretion from the isolated perfused rat pancreas.
Zeitschrift für Gastroenterologie 1990;28(7):348-52.
1990: Burkhard Göke; Volker Keim; J C Dagorn; Rudolf Arnold; Guido Adler
Resolution of human exocrine pancreatic juice proteins by reversed-phase high performance liquid chromatography (HPLC).
Pancreas 1990;5(3):261-6.
1990: Hans-Christoph Fehmann; Burkhard Göke; V Weber; Rüdiger Göke; M E Trautmann; G Richter; Rudolf Arnold
Interaction of glucagon-like peptide-1 (7-36)amide and cholecystokinin-8 in the endocrine and exocrine rat pancreas.
Pancreas 1990;5(3):361-5.
1990: T Matozaki; Burkhard Göke; Yasuhiro Tsunoda; M Rodriguez; J Martinez; John Williams
Two functionally distinct cholecystokinin receptors show different modes of action on Ca2+ mobilization and phospholipid hydrolysis in isolated rat pancreatic acini. Studies using a new cholecystokinin analog, JMV-180.
The Journal of biological chemistry 1990;265(11):6247-54.
1990: Burkhard Göke
A critical appraisal of studies of the pancreas. Animal models used in pancreas research: studies on feedback regulations of the pancreas.
International journal of pancreatology : official journal of the International Association of Pancreatology 1990;6(3):181-8.
1990: Hans-Christoph Fehmann; V Weber; Rüdiger Göke; Burkhard Göke; Rolf Eissele; Rudolf Arnold
Islet amyloid polypeptide (IAPP;amylin) influences the endocrine but not the exocrine rat pancreas.
Biochemical and biophysical research communications 1990;167(3):1102-8.
1990: Hans-Christoph Fehmann; V Weber; Rüdiger Göke; Burkhard Göke; Rudolf Arnold
Cosecretion of amylin and insulin from isolated rat pancreas.
FEBS letters 1990;262(2):279-81.
1990: Hans-Christoph Fehmann; B Noll; Rüdiger Göke; Burkhard Göke; M E Trautmann; Rudolf Arnold
Atrial natriuretic factor has a weak insulinotropic action in the isolated perfused rat pancreas.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1990;190(4):253-8.
1990: Karl-Heinz Herzig; D May; D S Louie; T Takahashi; Burkhard Göke; Chung Owyang
Intracellular mechanism responsible for reduced enzyme secretion from camostate-induced hypertrophied pancreas.
Digestion 1990;46 Suppl 2():195-201.
1989: B Noll; J Krappe; Burkhard Göke; Bernhard Maisch
Influence of pacing mode and rate on peripheral levels of atrial natriuretic peptide (ANP).
Pacing and clinical electrophysiology : PACE 1989;12(11):1763-8.
1989: Fritz Stöckmann; Hans-Christoph Fehmann; Burkhard Göke; EG Siegel; Werner Creutzfeldt
Impairment of stimulated insulin release from the isolated perfused rat pancreas by cyclosporine pretreatment.
Transplantation 1989;48(3):381-5.
1989: Rüdiger Göke; M E Trautmann; E Haus; G Richter; Hans-Christoph Fehmann; Rudolf Arnold; Burkhard Göke
Signal transmission after GLP-1(7-36)amide binding in RINm5F cells.
The American journal of physiology 1989;257(3 Pt 1):G397-401.
1989: Hans-Christoph Fehmann; Burkhard Göke; Rüdiger Göke; M E Trautmann; Rudolf Arnold
Synergistic stimulatory effect of glucagon-like peptide-1 (7-36) amide and glucose-dependent insulin-releasing polypeptide on the endocrine rat pancreas.
FEBS letters 1989;252(1-2):109-12.
1989: B Noll; Burkhard Göke; R Arnold
[Does atrial natriuretic peptide have physiologic significance?].
Deutsche medizinische Wochenschrift (1946) 1989;114(22):885-7.
1989: Fritz Stöckmann; Hans-Christoph Fehmann; R Haverich; Burkhard Göke; Werner Creutzfeldt
The effect of cyclosporin A on rat pancreatic B-cell: interaction with the calcium-antagonist diltiazem.
Experimental and clinical endocrinology 1989;93(2-3):213-8.
1989: Guido Adler; M Reinshagen; I Koop; Burkhard Göke; A Schafmayer; L C Rovati; Rudolf Arnold
Differential effects of atropine and a cholecystokinin receptor antagonist on pancreatic secretion.
Gastroenterology 1989;96(4):1158-64.
1989: Burkhard Göke; J Rüschoff; Wolf B Schwerk
[Monolobar (unilateral), secondary biliary liver cirrhosis in Klatskin tumor].
Zeitschrift für Gastroenterologie 1989;27(2):99-102.
1989: Paul Georg Lankisch; U Pohl; Burkhard Göke; J Otto; U Wereszczynska-Siemiatkowska; H J Gröne; G Rahlf
Effect of FOY-305 (camostate) on severe acute pancreatitis in two experimental animal models.
Gastroenterology 1989;96(1):193-9.
1989: G Richter; C Herrmann; Burkhard Göke; Rudolf Arnold
Release of tryptophan and serotonin into the portal vein of the isolated perfused rat small intestine.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1989;189(4):281-7.
1989: Rüdiger Göke; Hans-Christoph Fehmann; G Richter; M Trautmann; Burkhard Göke
Interaction of glucagon-like peptide-1(7-36)amide and somatostatin-14 in RINm5F cells and in the perfused rat pancreas.
Pancreas 1989;4(6):668-73.
1989: Rüdiger Göke; G Richter; Burkhard Göke; M Trautmann; Rudolf Arnold
Internalization of glucagon-like peptide-1(7-36)amide in rat insulinoma cells.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1989;189(4):257-64.
1989: Hans Weidenbach; Hartmut Printz; Burkhard Göke; I Koop; A Schafmayer; Guido Adler
Effect of atropine on feedback regulation of pancreatic secretion in rats.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1989;189(3):221-8.
1989: Burkhard Göke; J Leferink; Rüdiger Göke; Guido Adler
Effect of a low-molecular weight serine proteinase inhibitor (camostate) on amylase release from isolated pancreatic acini.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1989;189(1):33-8.
1988: B Noll; J Krappe; Burkhard Göke
[Modification of atrial natriuretic factor by the AV transmission time in pacemaker patients].
Deutsche medizinische Wochenschrift (1946) 1988;113(51-52):1994-6.
1988: Rüdiger Göke; Burkhard Göke; G Richter; Rudolf Arnold
[The entero-insular axis: the new incretin candidate glucagon-like peptide-1(7-36)amide (GLP-1(7-36))amide].
Zeitschrift für Gastroenterologie 1988;26(11):715-9.
1988: B Noll; Burkhard Göke; Hartmut Printz; J Gerberding; Volker Keim; Rudolf Arnold
Influence of experimental hyperthyroidism on the adult rat pancreas, small intestine, and blood gastrin levels.
Zeitschrift für Gastroenterologie 1988;26(6):331-6.
1988: Guido Adler; A Müllenhoff; T Bozkurt; Burkhard Göke; I Koop; Rudolf Arnold
Comparison of the effect of single and repeated administrations of a protease inhibitor (Camostate) on pancreatic secretion in man.
Scandinavian journal of gastroenterology 1988;23(2):158-62.
1988: Rüdiger Göke; Burkhard Göke; Hans Jürgen Steinfelder; R Arnold
Influence of a small molecular weight proteinase inhibitor, gabexate mesilate (FOY), on insulin receptor function in vitro.
International journal of pancreatology : official journal of the International Association of Pancreatology 1988;3(2-3):135-42.
1988: Guido Adler; A Müllenhoff; I Koop; T Bozkurt; Burkhard Göke; Christoph Beglinger; Rudolf Arnold
Stimulation of pancreatic secretion in man by a protease inhibitor (camostate).
European journal of clinical investigation 1988;18(1):98-104.
1988: Burkhard Göke; Volker Keim; T Meyer; Rudolf Arnold; Guido Adler
Identification of rat pancreatic secretory proteins after separation by high-performance liquid chromatography.
Pancreas 1988;3(2):199-206.
1988: B Noll; Burkhard Göke; S Willemer; G Richter; Rudolf Arnold
Influence of experimental hyperthyroidism on blood and myocardial serotonin in rats.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1988;188(6):433-42.
1988: Burkhard Göke; K Fenchel; S Knobloch; Rudolf Arnold; Guido Adler
Increased CCK-response to proteinase inhibitor feeding after induction of pancreatic hypertrophy in rats.
Pancreas 1988;3(5):576-9.
1987: Rainer Seitz; Burkhard Göke; R Egbring; P O Nowak; B E Strauer; Klaus Havemann
[Acute malignant myelofibrosis complicated by factor XIII deficiency, protein C decrease and skin necroses].
Der Internist 1987;28(9):623-7.
1987: Karl-Heinz Beckh; Burkhard Göke; R Müller; Rudolf Arnold
Elimination of the low-molecular weight proteinase inhibitor camostate (FOY 305) and its degradation products by the rat liver.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1987;187(6):401-6.
1986: Burkhard Göke; Hartmut Printz; I Koop; U Rausch; G Richter; R Arnold; G Adler
Endogenous CCK release and pancreatic growth in rats after feeding a proteinase inhibitor (camostate).
Pancreas 1986;1(6):509-15.