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Rajesh Gokhale

Research Profile

Chemicals & Drugs

Living Beings

Mycobacterium tuberculosis

Concepts & Ideas

Activities & Behaviors

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Computational Biology

Genes & Molecular Sequences

Procedures

Protein Sequence Analysis

Co-author Network

Publications

TOP 3
Archana Vats; Dipankar Chatterji; Tarun Chopra; DEBASISA MOHANTY; Raju Mukherjee; Madhu Sudhan Ravindran; Jean-Marc Reyrat; Anil Kumar Singh; Rajesh S Gokhale
Retrobiosynthetic approach delineates the biosynthetic pathway and the structure of the acyl chain of mycobacterial glycopeptidolipids.
Arush Chhabra; Aneesh Goyal; Asfarul S Haque; seema joshi; Ravi Kant Pal; Santosh Panjikar; Santosh Pasha; Rajkishore Rai; Rajan Sankaranarayanan; Rajesh S Gokhale
Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases.
DEBASISA MOHANTY; Rajan Sankaranarayanan; Rajesh S Gokhale
Fatty acyl-AMP ligases and polyketide synthases are unique enzymes of lipid biosynthetic machinery in Mycobacterium tuberculosis.

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All Publications

2012: Archana Vats; Dipankar Chatterji; Tarun Chopra; DEBASISA MOHANTY; Raju Mukherjee; Madhu Sudhan Ravindran; Jean-Marc Reyrat; Anil Kumar Singh; Rajesh S Gokhale
Retrobiosynthetic approach delineates the biosynthetic pathway and the structure of the acyl chain of mycobacterial glycopeptidolipids.
The Journal of biological chemistry 2012;287(36):30677-87.
2012: Arush Chhabra; Aneesh Goyal; Asfarul S Haque; seema joshi; Ravi Kant Pal; Santosh Panjikar; Santosh Pasha; Rajkishore Rai; Rajan Sankaranarayanan; Rajesh S Gokhale
Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(15):5681-6.
2011: DEBASISA MOHANTY; Rajan Sankaranarayanan; Rajesh S Gokhale
Fatty acyl-AMP ligases and polyketide synthases are unique enzymes of lipid biosynthetic machinery in Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2011;91(5):448-55.
2010: Pankaj Khurana; Rajesh S Gokhale; DEBASISA MOHANTY
Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles.
BMC bioinformatics 2010;11():57.
2009: Pooja Arora; Aneesh Goyal; vivek natarajan; Eerappa Rajakumara; Priyanka Verma; Radhika Gupta; Malikmohamed Yousuf; Omita A Trivedi; DEBASISA MOHANTY; Anil Tyagi; Rajan Sankaranarayanan; Rajesh S Gokhale
Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis.
Nature chemical biology 2009;5(3):166-73.
2008: Ratna Ghosh; Arush Chhabra; Pallavi A Phatale; Subodh K Samrat; Jyoti Sharma; Anuradha Gosain; DEBASISA MOHANTY; Shweta Saran; Rajesh S Gokhale
Dissecting the functional role of polyketide synthases in Dictyostelium discoideum: biosynthesis of the differentiation regulating factor 4-methyl-5-pentylbenzene-1,3-diol.
The Journal of biological chemistry 2008;283(17):11348-54.
2008: Mohd Zeeshan Ansari; Jyoti Sharma; Rajesh S Gokhale; DEBASISA MOHANTY
In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites.
BMC bioinformatics 2008;9():454.
2007: Rajesh S Gokhale; Rajan Sankaranarayanan; DEBASISA MOHANTY
Versatility of polyketide synthases in generating metabolic diversity.
Current opinion in structural biology 2007;17(6):736-43.
2007: Rajesh S Gokhale; Priti Saxena; Tarun Chopra; DEBASISA MOHANTY
Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids.
Natural product reports 2007;24(2):267-77.
2006: R Krithika; Uttara Marathe; Priti Saxena; Mohd Zeeshan Ansari; DEBASISA MOHANTY; Rajesh S Gokhale
A genetic locus required for iron acquisition in Mycobacterium tuberculosis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2069-74.
2005: Pooja Arora; Archana Vats; Priti Saxena; DEBASISA MOHANTY; Rajesh S Gokhale
Promiscuous fatty acyl CoA ligases produce acyl-CoA and acyl-SNAC precursors for polyketide biosynthesis.
Journal of the American Chemical Society 2005;127(26):9388-9.
2005: Pankaj Kamra; Rajesh S Gokhale; DEBASISA MOHANTY
SEARCHGTr: a program for analysis of glycosyltransferases involved in glycosylation of secondary metabolites.
Nucleic acids research 2005;33(Web Server issue):W220-5.
2005: Omita A Trivedi; Pooja Arora; Archana Vats; Mohd Zeeshan Ansari; rashmi shrivastava; Vijayalakshmi Sridharan; DEBASISA MOHANTY; Rajesh S Gokhale
Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid.
Molecular cell 2005;17(5):631-43.
2004: Mohd Zeeshan Ansari; Gitanjali Yadav; Rajesh S Gokhale; DEBASISA MOHANTY
NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases.
Nucleic acids research 2004;32(Web Server issue):W405-13.
2004: Omita A Trivedi; Pooja Arora; Vijayalakshmi Sridharan; rashmi shrivastava; DEBASISA MOHANTY; Rajesh S Gokhale
Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria.
Nature 2004;428(6981):441-5.
2003: Priti Saxena; Gitanjali Yadav; DEBASISA MOHANTY; Rajesh S Gokhale
A new family of type III polyketide synthases in Mycobacterium tuberculosis.
The Journal of biological chemistry 2003;278(45):44780-90.
2003: Gitanjali Yadav; Rajesh S Gokhale; DEBASISA MOHANTY
SEARCHPKS: A program for detection and analysis of polyketide synthase domains.
Nucleic acids research 2003;31(13):3654-8.
2003: Gitanjali Yadav; Rajesh S Gokhale; DEBASISA MOHANTY
Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases.
Journal of molecular biology 2003;328(2):335-63.