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Josée Golay

Research Profile

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Oncogenes

Physiology

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Erica Dander; Giuseppe Gaipa; Josée Golay; Martino Introna; Daniela Longoni; Giovanna Lucchini; F Masciocchi; Matteo Parma; Paolo Perseghin; Alessandro Rambaldi; Attilio Rovelli; P Vinci; Alessandra Algarotti; Adriana Balduzzi; Daniela Belotti; Ettore Biagi; Andrea Biondi; Sonia Bonanomi; C Capelli; Giovanna D'Amico
Mesenchymal stromal cells for the treatment of graft-versus-host disease: understanding the in vivo biological effect through patient immune monitoring.
Chiara Capelli; Giovanni Cazzaniga; Francesco Dazzi; Andrea Gianatti; Josée Golay; Elisa Gotti; Marina Morigi; Alessandro Rambaldi; Cinzia Rota; Orietta Spinelli; Rosangela Trezzi; Ling Weng; Martino Introna
Minimally manipulated whole human umbilical cord is a rich source of clinical-grade human mesenchymal stromal cells expanded in human platelet lysate.
Giovanna Lucchini; Martino Introna; Erica Dander; Attilio Rovelli; Adriana Balduzzi; Sonia Bonanomi; Agnese Salvadè; Chiara Capelli; Daniela Belotti; Giuseppe Gaipa; Paolo Perseghin; Paola Vinci; Edoardo Lanino; Patrizia Chiusolo; Maria Grazia Orofino; Sarah Marktel; Josée Golay; Alessandro Rambaldi; Andrea Biondi; Giovanna D'Amico; Ettore Biagi
Platelet-lysate-expanded mesenchymal stromal cells as a salvage therapy for severe resistant graft-versus-host disease in a pediatric population.

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All Publications

2012: Erica Dander; Giuseppe Gaipa; Josée Golay; Martino Introna; Daniela Longoni; Giovanna Lucchini; F Masciocchi; Matteo Parma; Paolo Perseghin; Alessandro Rambaldi; Attilio Rovelli; P Vinci; Alessandra Algarotti; Adriana Balduzzi; Daniela Belotti; Ettore Biagi; Andrea Biondi; Sonia Bonanomi; C Capelli; Giovanna D'Amico
Mesenchymal stromal cells for the treatment of graft-versus-host disease: understanding the in vivo biological effect through patient immune monitoring.
Leukemia 2012;26(7):1681-4.
2011: Chiara Capelli; Giovanni Cazzaniga; Francesco Dazzi; Andrea Gianatti; Josée Golay; Elisa Gotti; Marina Morigi; Alessandro Rambaldi; Cinzia Rota; Orietta Spinelli; Rosangela Trezzi; Ling Weng; Martino Introna
Minimally manipulated whole human umbilical cord is a rich source of clinical-grade human mesenchymal stromal cells expanded in human platelet lysate.
Cytotherapy 2011;13(7):786-801.
2010: Giovanna Lucchini; Martino Introna; Erica Dander; Attilio Rovelli; Adriana Balduzzi; Sonia Bonanomi; Agnese Salvadè; Chiara Capelli; Daniela Belotti; Giuseppe Gaipa; Paolo Perseghin; Paola Vinci; Edoardo Lanino; Patrizia Chiusolo; Maria Grazia Orofino; Sarah Marktel; Josée Golay; Alessandro Rambaldi; Andrea Biondi; Giovanna D'Amico; Ettore Biagi
Platelet-lysate-expanded mesenchymal stromal cells as a salvage therapy for severe resistant graft-versus-host disease in a pediatric population.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(9):1293-301.
2008: Josée Golay; Martino Introna
Chemokines and antagonists in non-Hodgkin's lymphoma.
Expert opinion on therapeutic targets 2008;12(5):621-35.
2007: C Capelli; M Domenghini; Gianmaria Borleri; Piermario Bellavita; Rossana Poma; A Carobbio; Caterina Micò; Alessandro Rambaldi; Josée Golay; Martino Introna
Human platelet lysate allows expansion and clinical grade production of mesenchymal stromal cells from small samples of bone marrow aspirates or marrow filter washouts.
Bone marrow transplantation 2007;40(8):785-91.
2007: Josée Golay; L Cuppini; Franco Leoni; Caterina Micò; V Barbui; M Domenghini; L Lombardi; A Neri; Anna Maria Barbui; Anna Salvi; Pietro Pozzi; Giulia Porro; Paolo Pagani; Gianluca Fossati; Paolo Mascagni; Martino Introna; Alessandro Rambaldi
The histone deacetylase inhibitor ITF2357 has anti-leukemic activity in vitro and in vivo and inhibits IL-6 and VEGF production by stromal cells.
Leukemia 2007;21(9):1892-900.
2007: Martino Introna; Gianmaria Borleri; Elena Conti; Marta Franceschetti; Anna Maria Barbui; Raewyn Broady; Erica Dander; Giuseppe Gaipa; Giovanna D'Amico; Ettore Biagi; Matteo Parma; Enrico Pogliani; Orietta Spinelli; Donatella Baronciani; Anna Grassi; Josée Golay; Tiziano Barbui; Andrea Biondi; Alessandro Rambaldi
Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study.
Haematologica 2007;92(7):952-9.
2007: Elena Cittera; Marzia Leidi; Chiara Buracchi; Fabio Pasqualini; Silvano Sozzani; Annunciata Vecchi; J Douglas Waterfield; Martino Introna; Josée Golay
The CCL3 family of chemokines and innate immunity cooperate in vivo in the eradication of an established lymphoma xenograft by rituximab.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6616-23.
2006: Martino Introna; M Franceschetti; A Ciocca; Gianmaria Borleri; Elena Conti; Josée Golay; Alessandro Rambaldi
Rapid and massive expansion of cord blood-derived cytokine-induced killer cells: an innovative proposal for the treatment of leukemia relapse after cord blood transplantation.
Bone marrow transplantation 2006;38(9):621-7.
2006: Josée Golay; Chiara Cortiana; Massimiliano Manganini; Giovanni Cazzaniga; Anna Salvi; Orietta Spinelli; Renato Bassan; Tiziano Barbui; Andrea Biondi; Alessandro Rambaldi; Martino Introna
The sensitivity of acute lymphoblastic leukemia cells carrying the t(12;21) translocation to campath-1H-mediated cell lysis.
Haematologica 2006;91(3):322-30.
2006: Josée Golay; Elena Cittera; Nicola Di Gaetano; Massimiliano Manganini; Michela Mosca; Manuela Nebuloni; Nico van Rooijen; Luca Vago; Martino Introna
The role of complement in the therapeutic activity of rituximab in a murine B lymphoma model homing in lymph nodes.
Haematologica 2006;91(2):176-83.
2005: Elena Cittera; Chiara Onofri; Maria D'Apolito; Guillaume Cartron; Giovanni Cazzaniga; Leopoldo Zelante; Paolo Paolucci; Andrea Biondi; Martino Introna; Josée Golay
Rituximab induces different but overlapping sets of genes in human B-lymphoma cell lines.
Cancer immunology, immunotherapy : CII 2005;54(3):273-86.
2005: Josée Golay; Nicola Di Gaetano; D Amico; Elena Cittera; Anna Maria Barbui; R Giavazzi; Andrea Biondi; Alessandro Rambaldi; Martino Introna
Gemtuzumab ozogamicin (Mylotarg) has therapeutic activity against CD33 acute lymphoblastic leukaemias in vitro and in vivo.
British journal of haematology 2005;128(3):310-7.
2004: Josée Golay; Massimiliano Manganini; Alessandro Rambaldi; Martino Introna
Effect of alemtuzumab on neoplastic B cells.
Haematologica 2004;89(12):1476-83.
2004: Guillaume Cartron; Hervé Watier; Josée Golay; Philippe Solal-Celigny
From the bench to the bedside: ways to improve rituximab efficacy.
Blood 2004;104(9):2635-42.
2004: Martino Introna; Anna Maria Barbui; Josée Golay; Alessandro Rambaldi
Innovative cell-based therapies in onco-hematology: what are the clinical facts ?
Haematologica 2004;89(10):1253-60.
2004: Marta Serafini; Massimiliano Manganini; Gianmaria Borleri; Martin Bonamino; L Imberti; Andrea Biondi; Josée Golay; Alessandro Rambaldi; Martino Introna
Characterization of CD20-transduced T lymphocytes as an alternative suicide gene therapy approach for the treatment of graft-versus-host disease.
Human gene therapy 2004;15(1):63-76.
2004: Marta Serafini; Martin Bonamino; Josée Golay; Martino Introna
Elongation factor 1 (EF1alpha) promoter in a lentiviral backbone improves expression of the CD20 suicide gene in primary T lymphocytes allowing efficient rituximab-mediated lysis.
Haematologica 2004;89(1):86-95.
2004: Martin Bonamino; Marta Serafini; Giovanna D'Amico; Giuseppe Gaipa; Elisabetta Todisco; Sergio Bernasconi; Josée Golay; Andrea Biondi; Martino Introna
Functional transfer of CD40L gene in human B-cell precursor ALL blasts by second-generation SIN lentivectors.
Gene therapy 2004;11(1):85-93.
2003: Josée Golay; Massimiliano Manganini; Valeria Facchinetti; Rosanna Gramigna; Raewyn Broady; Gianmaria Borleri; Alessandro Rambaldi; Martino Introna
Rituximab-mediated antibody-dependent cellular cytotoxicity against neoplastic B cells is stimulated strongly by interleukin-2.
Haematologica 2003;88(9):1002-12.
2003: Nicola Di Gaetano; Elena Cittera; Rachele Nota; Annunciata Vecchi; Valeria Grieco; Eugenio Scanziani; Marina Botto; Martino Introna; Josée Golay
Complement activation determines the therapeutic activity of rituximab in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1581-7.
2003: Donatella Amico; Anna Maria Barbui; Eugenio Erba; Alessandro Rambaldi; Martino Introna; Josée Golay
Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3.
Blood 2003;101(11):4589-97.
2003: Martino Introna; Josée Golay; Tiziano Barbui
Rituximab: a new therapeutic tool for primary immune thrombocytopenic purpura?
Haematologica 2003;88(5):482-4.
2003: Michele Luchetti; Paolo Paroncini; Petra Majlingovà; Jon Frampton; Michael Mucenski; Silvia Svegliati Baroni; Paola Sambo; Josée Golay; Martino Introna; Armando Gabrielli
Characterization of the c-Myb-responsive region and regulation of the human type I collagen alpha 2 chain gene by c-Myb.
The Journal of biological chemistry 2003;278(3):1533-41.
2002: Josée Golay; Rosanna Gramigna; Valeria Facchinetti; Daniela Capello; Gianluca Gaidano; Martino Introna
Acquired immunodeficiency syndrome-associated lymphomas are efficiently lysed through complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity by rituximab.
British journal of haematology 2002;119(4):923-9.
2002: Massimiliano Manganini; Marta Serafini; Federica Bambacioni; Chiara Casati; Eugenio Erba; Antonia Follenzi; Luigi Naldini; Sergio Bernasconi; Giuseppe Gaipa; Alessandro Rambaldi; Andrea Biondi; Josée Golay; Martino Introna
A human immunodeficiency virus type 1 pol gene-derived sequence (cPPT/CTS) increases the efficiency of transduction of human nondividing monocytes and T lymphocytes by lentiviral vectors.
Human gene therapy 2002;13(15):1793-807.
2001: Josée Golay; M Lazzari; Valeria Facchinetti; Sergio Bernasconi; Gianmaria Borleri; Tiziano Barbui; Alessandro Rambaldi; Martino Introna
CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59.
Blood 2001;98(12):3383-9.
2001: Federica Bambacioni; Chiara Casati; Marta Serafini; Massimiliano Manganini; Josée Golay; Martino Introna
Lentiviral vectors show dramatically increased efficiency of transduction of human leukemic cell lines.
Haematologica 2001;86(10):1095-6.
2001: Nicola Di Gaetano; Y Xiao; Eugenio Erba; Renato Bassan; Alessandro Rambaldi; Josée Golay; Martino Introna
Synergism between fludarabine and rituximab revealed in a follicular lymphoma cell line resistant to the cytotoxic activity of either drug alone.
British journal of haematology 2001;114(4):800-9.
2001: Ettore Biagi; Federica Bambacioni; Giuseppe Gaipa; Chiara Casati; Josée Golay; Andrea Biondi; Martino Introna
Efficient lentiviral transduction of primary human acute myelogenous and lymphoblastic leukemia cells.
Haematologica 2001;86(1):13-6.
2000: Valeria Facchinetti; R Lopa; F Spreafico; Fabrizio Bolognese; Roberto Mantovani; Fiona J Tavner; R Watson; Martino Introna; Josée Golay
Isolation and characterization of the human A-myb promoter: regulation by NF-Y and Sp1.
Oncogene 2000;19(34):3931-40.
2000: Marcello Arsura; C S Hofmann; Josée Golay; Martino Introna; Gail E Sonenshein
A-myb rescues murine B-cell lymphomas from IgM-receptor-mediated apoptosis through c-myc transcriptional regulation.
Blood 2000;96(3):1013-20.
2000: Josée Golay; L Zaffaroni; T Vaccari; M Lazzari; Gianmaria Borleri; Sergio Bernasconi; Francesco Tedesco; Alessandro Rambaldi; Martino Introna
Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis.
Blood 2000;95(12):3900-8.
2000: Caroline A Heckman; John W Mehew; G G Ying; Martino Introna; Josée Golay; Linda M Boxer
A-Myb up-regulates Bcl-2 through a Cdx binding site in t(14;18) lymphoma cells.
The Journal of biological chemistry 2000;275(9):6499-508.
2000: Martino Introna; Anna Maria Barbui; Federica Bambacioni; Chiara Casati; Giuseppe Gaipa; Gianmaria Borleri; Sergio Bernasconi; Tiziano Barbui; Josée Golay; Andrea Biondi; Alessandro Rambaldi
Genetic modification of human T cells with CD20: a strategy to purify and lyse transduced cells with anti-CD20 antibodies.
Human gene therapy 2000;11(4):611-20.
2000: G G Ying; P Proost; J van Damme; M Bruschi; Martino Introna; Josée Golay
Nucleolin, a novel partner for the Myb transcription factor family that regulates their activity.
The Journal of biological chemistry 2000;275(6):4152-8.
1999: Martino Introna; Josée Golay
How can oncogenic transcription factors cause cancer: a critical review of the myb story.
Leukemia 1999;13(9):1301-6.
1999: Alessandra Mortellaro; S Songia; P Gnocchi; M Ferrari; C Fornasiero; Roberto D'Alessio; AM Isetta; F Colotta; Josée Golay
New immunosuppressive drug PNU156804 blocks IL-2-dependent proliferation and NF-kappa B and AP-1 activation.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7102-9.
1999: Gina Piccinini; Josée Golay; A Flora; S Songia; Michele Luchetti; Armando Gabrielli; Martino Introna
C-myb, but not B-myb, upregulates type I collagen gene expression in human fibroblasts.
The Journal of investigative dermatology 1999;112(2):191-6.
1998: Martino Introna; Anna Maria Barbui; Josée Golay; Federica Bambacioni; R Schirò; Sergio Bernasconi; Ferruccio Breviario; Eugenio Erba; Gianmaria Borleri; Tiziano Barbui; Andrea Biondi; Alessandro Rambaldi
Rapid retroviral infection of human haemopoietic cells of different lineages: efficient transfer in fresh T cells.
British journal of haematology 1998;103(2):449-61.
1998: Josée Golay; V Broccoli; Giuseppe Lamorte; C Bifulco; C Parravicini; A Pizzey; N S Thomas; Domenico Delia; P Ferrauti; Domenico Vitolo; Martino Introna
The A-Myb transcription factor is a marker of centroblasts in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2786-93.
1997: Josée Golay; V Broccoli; Gianmaria Borleri; Eugenio Erba; Mario Faretta; L Basilico; G G Ying; Gina Piccinini; Linda H. Shapiro; J Lovrić; Michael Nawrath; K Mölling; Alessandro Rambaldi; Martino Introna
Redundant functions of B-Myb and c-Myb in differentiating myeloid cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(12):1305-16.
1997: G G Ying; Marcello Arsura; Martino Introna; Josée Golay
The DNA binding domain of the A-MYB transcription factor is responsible for its B cell-specific activity and binds to a B cell 110-kDa nuclear protein.
The Journal of biological chemistry 1997;272(40):24921-6.
1997: Josée Golay; Valeria Facchinetti; G Ying; Martino Introna
The A-myb transcription factor in neoplastic and normal B cells.
Leukemia & lymphoma 1997;26(3-4):271-9.
1997: Valeria Facchinetti; L Loffarelli; Sabine Schreek; M Oelgeschläger; Bernhard Lüscher; Martino Introna; Josée Golay
Regulatory domains of the A-Myb transcription factor and its interaction with the CBP/p300 adaptor molecules.
The Biochemical journal 1997;324 ( Pt 3)():729-36.
1997: Corrado Caslini; Orietta Spinelli; Giovanni Cazzaniga; Josée Golay; Luca De Gioia; A Pedretti; Ferruccio Breviario; Ricardo Amaru; Tiziano Barbui; Andrea Biondi; Martino Introna; Alessandro Rambaldi
Identification of two novel isoforms of the ZNF162 gene: a growing family of signal transduction and activator of RNA proteins.
Genomics 1997;42(2):268-77.
1997: S Songia; Alessandra Mortellaro; S Taverna; C Fornasiero; E A Scheiber; Eugenio Erba; F Colotta; A Mantovani; AM Isetta; Josée Golay
Characterization of the new immunosuppressive drug undecylprodigiosin in human lymphocytes: retinoblastoma protein, cyclin-dependent kinase-2, and cyclin-dependent kinase-4 as molecular targets.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3987-95.
1996: Josée Golay; M Luppi; S Songia; C Palvarini; L Lombardi; A Aiello; Domenico Delia; K Lam; D H Crawford; A Biondi; T Barbui; A Rambaldi; Martino Introna
Expression of A-myb, but not c-myb and B-myb, is restricted to Burkitt's lymphoma, sIg+ B-acute lymphoblastic leukemia, and a subset of chronic lymphocytic leukemias.
Blood 1996;87(5):1900-11.
1996: Josée Golay; L Basilico; L Loffarelli; S Songia; V Broccoli; Martino Introna
Regulation of hematopoietic cell proliferation and differentiation by the myb oncogene family of transcription factors.
International journal of clinical & laboratory research 1996;26(1):24-32.
1995: Ferruccio Breviario; L Caveda; Monica Corada; Ines Martin-Padura; P Navarro; Josée Golay; Martino Introna; D Gulino; Maria Grazia Lampugnani; Elisabetta Dejana
Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(8):1229-39.
1994: V V Alles; B Bottazzi; Giuseppe Peri; Josée Golay; Martino Introna; A Mantovani
Inducible expression of PTX3, a new member of the pentraxin family, in human mononuclear phagocytes.
Blood 1994;84(10):3483-93.
1994: Josée Golay; L Loffarelli; M Luppi; M Castellano; Martino Introna
The human A-myb protein is a strong activator of transcription.
Oncogene 1994;9(9):2469-79.
1994: Josée Golay; Eugenio Erba; S Bernasconi; Giuseppe Peri; Martino Introna
The A-myb gene is preferentially expressed in tonsillar CD38+, CD39-, and sIgM- B lymphocytes and in Burkitt's lymphoma cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(2):543-53.
1994: Marcello Arsura; Michele Luchetti; Eugenio Erba; Josée Golay; Alessandro Rambaldi; Martino Introna
Dissociation between p93B-myb and p75c-myb expression during the proliferation and differentiation of human myeloid cell lines.
Blood 1994;83(7):1778-90.
1994: Martino Introna; Michele Luchetti; M Castellano; Marcello Arsura; Josée Golay
The myb oncogene family of transcription factors: potent regulators of hematopoietic cell proliferation and differentiation.
Seminars in cancer biology 1994;5(2):113-24.
1993: Martino Introna; Ferruccio Breviario; E M d'Aniello; Josée Golay; Elisabetta Dejana; A Mantovani
IL-1 inducible genes in human umbilical vein endothelial cells.
European heart journal 1993;14 Suppl K():78-81.
1992: Ferruccio Breviario; E M d'Aniello; Josée Golay; Giuseppe Peri; B Bottazzi; Amos Bairoch; S Saccone; R Marzella; V Predazzi; M Rocchi
Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component.
The Journal of biological chemistry 1992;267(31):22190-7.
1992: Josée Golay; G Cusmano; Martino Introna
Independent regulation of c-myc, B-myb, and c-myb gene expression by inducers and inhibitors of proliferation in human B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(1):300-8.
1992: Marcello Arsura; Martino Introna; F Passerini; A Mantovani; Josée Golay
B-myb antisense oligonucleotides inhibit proliferation of human hematopoietic cell lines.
Blood 1992;79(10):2708-16.
1992: M Castellano; Josée Golay; A Mantovani; Martino Introna
Detection of a transcriptional block in the first intron of the human c-myb gene.
International journal of clinical & laboratory research 1992;22(3):159-64.
1991: Josée Golay; F Passerini; Martino Introna
A simple and rapid method to analyze specific mRNAs from few cells in a semi-quantitative way using the polymerase chain reaction.
PCR methods and applications 1991;1(2):144-5.
1991: Josée Golay; Alessandro Capucci; Marcello Arsura; M Castellano; V Rizzo; Martino Introna
Expression of c-myb and B-myb, but not A-myb, correlates with proliferation in human hematopoietic cells.
Blood 1991;77(1):149-58.
1990: Martino Introna; Josée Golay; Jon Frampton; T Nakano; S A Ness; Thomas Graf
Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene.
Cell 1990;63(6):1289-97.
1988: Josée Golay; Martino Introna; Thomas Graf
A single point mutation in the v-ets oncogene affects both erythroid and myelomonocytic cell differentiation.
Cell 1988;55(6):1147-58.