FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Barry Gold

Research Profile

Chemicals & Drugs

Concepts & Ideas

Physiology

Disorders

DNA Damage

Occupations

Thermodynamics

Phenomena

Living Beings

Mouse

Co-author Network

Publications

TOP 3
Ajay Srinivasan; Lirong Wang; Xiang-Qun Xie; Zhaojun Xie; Cari J Cline; Robert W Sobol; Barry Gold
Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors.
Ajay Srinivasan; Barry Gold
Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.
Manjori Ganguly; Kate Clancy; Patrick S Donahue; Michael P Stone; Marta W Szulik; Barry Gold
Thermodynamic signature of DNA damage: characterization of DNA with a 5-hydroxy-2'-deoxycytidine·2'-deoxyguanosine base pair.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Barry Gold (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Ajay Srinivasan; Lirong Wang; Xiang-Qun Xie; Zhaojun Xie; Cari J Cline; Robert W Sobol; Barry Gold
Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors.
Biochemistry 2012;51(31):6246-59.
2012: Ajay Srinivasan; Barry Gold
Small-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.
Future medicinal chemistry 2012;4(9):1093-111.
2012: Manjori Ganguly; Kate Clancy; Patrick S Donahue; Michael P Stone; Marta W Szulik; Barry Gold
Thermodynamic signature of DNA damage: characterization of DNA with a 5-hydroxy-2'-deoxycytidine·2'-deoxyguanosine base pair.
Biochemistry 2012;51(9):2018-27.
2011: Ewa A Kowal; Luis A Marky; Pradeep S Pallan; Martin Egli; Manjori Ganguly; Barry Gold; Michael P Stone
Altering the electrostatic potential in the major groove: thermodynamic and structural characterization of 7-deaza-2'-deoxyadenosine:dT base pairing in DNA.
The journal of physical chemistry. B 2011;115(47):13925-34.
2011: Paola Monti; Silvia Tornaletti; Ruo-wen Wang; Christopher Broxson; Barry Gold; Alberto Inga; Paola Menichini; Gilberto Fronza
3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.
DNA repair 2011;10(8):861-8.
2011: Sreelekha K Singh; Michael P Stone; Marta W Szulik; Manjori Ganguly; Irine Khutsishvili; Luis A Marky; Barry Gold
Characterization of DNA with an 8-oxoguanine modification.
Nucleic acids research 2011;39(15):6789-801.
2010: Emily H Rubinson; A S Prakasha Gowda; Thomas E Spratt; Barry Gold; Brandt Eichman
An unprecedented nucleic acid capture mechanism for excision of DNA damage.
Nature 2010;468(7322):406-11.
2010: Debora Russo; Gilberto Fronza; Laura Ottaggio; Paola Monti; Chiara Perfumo; Alberto Inga; Prema Iyer; Barry Gold; Paola Menichini
XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine.
DNA repair 2010;9(7):728-36.
2010: Manjori Ganguly; Ruo-Wen Wang; Luis A Marky; Barry Gold
Thermodynamic characterization of DNA with 3-deazaadenine and 3-methyl-3-deazaadenine substitutions: the effect of placing a hydrophobic group in the minor groove of DNA.
The journal of physical chemistry. B 2010;114(22):7656-61.
2010: Lucio Tentori; Alessia Muzi; A S Dorio; Marco Scarsella; C Leonetti; G M Shah; Weizheng Xu; E Camaioni; Barry Gold; R Pellicciari; F Dantzer; Jie Zhang; Grazia Graziani
Pharmacological inhibition of poly(ADP-ribose) polymerase (PARP) activity in PARP-1 silenced tumour cells increases chemosensitivity to temozolomide and to a N3-adenine selective methylating agent.
Current cancer drug targets 2010;10(4):368-83.
2010: Paola Monti; Ilaria Traverso; Laura Casolari; Paola Menichini; Alberto Inga; Laura Ottaggio; Debora Russo; Prema Iyer; Barry Gold; Gilberto Fronza
Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair.
Mutation research 2010;683(1-2):50-6.
2010: Samuel Settles; Ruo-Wen Wang; Gilberto Fronza; Barry Gold
Effect of n3-methyladenine and an isosteric stable analogue on DNA polymerization.
Journal of nucleic acids 2010;2010():.
2009: Debora Russo; Gilberto Fronza; Laura Ottaggio; Paola Monti; Alberto Inga; Prema Iyer; Barry Gold; Paola Menichini
High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells.
Mutation research 2009;671(1-2):58-66.
2009: Manjori Ganguly; Ruo-Wen Wang; Luis A Marky; Barry Gold
Introduction of cationic charge into DNA near the major groove edge of a guanine x cytosine base pair: characterization of oligodeoxynucleotides substituted with 7-aminomethyl-7-deaza-2'-deoxyguanosine.
Journal of the American Chemical Society 2009;131(34):12068-9.
2009: Ruo-Wen Wang; Barry Gold
A facile synthetic approach to 7-deazaguanine nucleosides via a Boc protection strategy.
Organic letters 2009;11(11):2465-8.
2008: Feng Wang; Feng Li; Manjori Ganguly; Luis A Marky; Barry Gold; Martin Egli; Michael P Stone
A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.
Biochemistry 2008;47(27):7147-57.
2008: Paola Monti; Yari Ciribilli; Debora Russo; Alessandra Bisio; Chiara Perfumo; Virginia Andreotti; Paola Menichini; Alberto Inga; Xiaofen Huang; Barry Gold; Gilberto Fronza
Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent.
DNA repair 2008;7(3):431-8.
2007: Nicole Burns; Barry Gold
The effect of 3-methyladenine DNA glycosylase-mediated DNA repair on the induction of toxicity and diabetes by the beta-cell toxicant streptozotocin.
Toxicological sciences : an official journal of the Society of Toxicology 2007;95(2):391-400.
2007: Manjori Ganguly; Feng Wang; Mahima Kaushik; Michael P Stone; Luis A Marky; Barry Gold
A study of 7-deaza-2'-deoxyguanosine 2'-deoxycytidine base pairing in DNA.
Nucleic acids research 2007;35(18):6181-95.
2006: Barry Gold; Luis M Marky; Michael P Stone; Loren Dean Williams
A review of the role of the sequence-dependent electrostatic landscape in DNA alkylation patterns.
Chemical research in toxicology 2006;19(11):1402-14.
2005: Lucio Tentori; Carlo Leonetti; Marco Scarsella; Alessia Muzi; Matteo Vergati; Olindo Forini; Pedro Miguel Lacal; Federica Ruffini; Barry Gold; Weixing Li; Jie Zhang; Grazia Graziani
Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide.
European journal of cancer (Oxford, England : 1990) 2005;41(18):2948-57.
2005: Jian-Sen Li; Barry Gold
Synthesis of C-nucleosides designed to participate in triplex formation with native DNA: specific recognition of an A:T base pair in DNA.
The Journal of organic chemistry 2005;70(22):8764-71.
2005: Ronald Shikiya; Jian-Sen Li; Barry Gold; Luis A Marky
Incorporation of cationic chains in the Dickerson-Drew dodecamer: correlation of energetics, structure, and ion and water binding.
Biochemistry 2005;44(37):12582-8.
2005: Jian-Sen Li; Fa-xian Chen; Ronald Shikiya; Luis A Marky; Barry Gold
Molecular recognition via triplex formation of mixed purine/pyrimidine DNA sequences using oligoTRIPs.
Journal of the American Chemical Society 2005;127(36):12657-65.
2005: Tinoush Moulaei; Tatsuya Maehigashi; George T Lountos; Seiji Komeda; Derrick Watkins; Michael P Stone; Luis A Marky; Jian-sen Li; Barry Gold; Loren Dean Williams
Structure of B-DNA with cations tethered in the major groove.
Biochemistry 2005;44(20):7458-68.
2005: Lucio Tentori; Olindo Forini; Emanuela Fossile; Alessia Muzi; Matteo Vergati; Ilaria Portarena; Carla Amici; Barry Gold; Grazia Graziani
N3-methyladenine induces early poly(ADP-ribosylation), reduction of nuclear factor-kappa B DNA binding ability, and nuclear up-regulation of telomerase activity.
Molecular pharmacology 2005;67(2):572-81.
2004: Paola Monti; Raffaella Iannone; Paola Campomenosi; Yari Ciribilli; Sridhar Varadarajan; Dharini Shah; Paola Menichini; Barry Gold; Gilberto Fronza
Nucleotide excision repair defect influences lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent in the absence of base excision repair.
Biochemistry 2004;43(19):5592-9.
2004: Jian-Sen Li; Ronald Shikiya; Luis A Marky; Barry Gold
Triple helix forming TRIPside molecules that target mixed purine/pyrimidine DNA sequences.
Biochemistry 2004;43(6):1440-8.
2004: Gilberto Fronza; Barry Gold
The biological effects of N3-methyladenine.
Journal of cellular biochemistry 2004;91(2):250-7.
2003: Sridhar Varadarajan; Dharini Shah; Prasad Dande; Samuel Settles; Fa-xian Chen; Gilberto Fronza; Barry Gold
DNA damage and cytotoxicity induced by minor groove binding methyl sulfonate esters.
Biochemistry 2003;42(48):14318-27.
2003: Dharini Shah; Barry Gold
Evidence in Escherichia coli that N3-methyladenine lesions and cytotoxicity induced by a minor groove binding methyl sulfonate ester can be modulated in vivo by netropsin.
Biochemistry 2003;42(43):12610-6.
2003: Jian-Sen Li; Yun-Hua Fan; Yi Zhang; Luis A Marky; Barry Gold
Design of triple helix forming C-glycoside molecules.
Journal of the American Chemical Society 2003;125(8):2084-93.
2003: Lucio Tentori; Ilaria Portarena; Marcella Barbarino; Alessandra Balduzzi; Lauretta Levati; Matteo Vergati; Annamaria Biroccio; Barry Gold; Maria Luisa Lombardi; Grazia Graziani
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.
Molecular pharmacology 2003;63(1):192-202.
2002: Barry Gold
Effect of cationic charge localization on DNA structure.
Biopolymers 2002;65(3):173-9.
2002: Paola Monti; Paola Campomenosi; Yari Ciribilli; Raffaella Iannone; Alberto Inga; Dharini Shah; Gina Scott; Philip A Burns; Paola Menichini; Angelo Abbondandolo; Barry Gold; Gilberto Fronza
Influences of base excision repair defects on the lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent.
The Journal of biological chemistry 2002;277(32):28663-8.
2002: Zhijun Li; Li Huang; Prasad Dande; Barry Gold; Michael P Stone
Structure of a tethered cationic 3-aminopropyl chain incorporated into an oligodeoxynucleotide: evidence for 3'-orientation in the major groove accompanied by DNA bending.
Journal of the American Chemical Society 2002;124(29):8553-60.
2002: Ana Maria Soto; Besik I Kankia; Prasad Dande; Barry Gold; Luis A Marky
Thermodynamic and hydration effects for the incorporation of a cationic 3-aminopropyl chain into DNA.
Nucleic acids research 2002;30(14):3171-80.
2002: Lucio Tentori; Ilaria Portarena; Patrizia Vernole; Barry Gold; Grazia Graziani
Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes.
Cancer chemotherapy and pharmacology 2002;49(3):217-24.
2001: Ana Maria Soto; Besik I Kankia; Prasad Dande; Barry Gold; Luis A Marky
Incorporation of a cationic aminopropyl chain in DNA hairpins: thermodynamics and hydration.
Nucleic acids research 2001;29(17):3638-45.
2001: Lucio Tentori; Alessandra Balduzzi; Ilaria Portarena; Lauretta Levati; Patrizia Vernole; Barry Gold; Enzo Bonmassar; Grazia Graziani
Poly (ADP-ribose) polymerase inhibitor increases apoptosis and reduces necrosis induced by a DNA minor groove binding methyl sulfonate ester.
Cell death and differentiation 2001;8(8):817-28.
2001: Paola Campomenosi; Paola Monti; Anna Aprile; Angelo Abbondandolo; Thierry Frebourg; Barry Gold; T Crook; Alberto Inga; Michael A Resnick; Richard D Iggo; Gilberto Fronza
p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
Oncogene 2001;20(27):3573-9.
2001: Dharini Shah; J Kelly; Y Zhang; Prasad Dande; J Martinez; G Ortiz; Gilberto Fronza; H Tran; Ana Maria Soto; Luis A Marky; Barry Gold
Evidence in Escherichia coli that N3-methyladenine lesions induced by a minor groove binding methyl sulfonate ester can be processed by both base and nucleotide excision repair.
Biochemistry 2001;40(6):1796-803.
2000: Lucio Tentori; Patrizia Vernole; Pedro Miguel Lacal; R Madaio; Ilaria Portarena; Lauretta Levati; Alessandra Balduzzi; Mario Turriziani; Prasad Dande; Barry Gold; Enzo Bonmassar; Grazia Graziani
Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cells.
Leukemia 2000;14(8):1451-9.
2000: Gilberto Fronza; Alberto Inga; Paola Monti; Gina Scott; Paola Campomenosi; Paola Menichini; Laura Ottaggio; Silvia Viaggi; Philip A Burns; Barry Gold; Angelo Abbondandolo
The yeast p53 functional assay: a new tool for molecular epidemiology. Hopes and facts.
Mutation research 2000;462(2-3):293-301.
1999: J D Kelly; Alberto Inga; Fa-xian Chen; Prasad Dande; Dharini Shah; Paola Monti; Anna Aprile; Philip A Burns; Gina Scott; Angelo Abbondandolo; Barry Gold; Gilberto Fronza
Relationship between DNA methylation and mutational patterns induced by a sequence selective minor groove methylating agent.
The Journal of biological chemistry 1999;274(26):18327-34.
1999: Alberto Inga; Fa-xian Chen; Paola Monti; Anna Aprile; Paola Campomenosi; Paola Menichini; Laura Ottaggio; Silvia Viaggi; Angelo Abbondandolo; Barry Gold; Gilberto Fronza
N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenic.
Cancer research 1999;59(3):689-95.
1998: J D Kelly; Dharini Shah; Fa-xian Chen; R Wurdeman; Barry Gold
Quantitative and qualitative analysis of DNA methylation at N3-adenine by N-methyl-N-nitrosourea.
Chemical research in toxicology 1998;11(12):1481-6.
1997: Prasad Dande; G Liang; Fa-xian Chen; C Roberts; M G Nelson; H Hashimoto; C Switzer; Barry Gold
Regioselective effect of zwitterionic DNA substitutions on DNA alkylation: evidence for a strong side chain orientational preference.
Biochemistry 1997;36(20):6024-32.
1996: P Mehta; K Church; J Williams; Fa-xian Chen; L Encell; D E Shuker; Barry Gold
The design of agents to control DNA methylation adducts. Enhanced major groove methylation of DNA by an N-methyl-N-nitrosourea functionalized phenyl neutral red intercalator.
Chemical research in toxicology 1996;9(6):939-48.
1996: L Encell; P G Foiles; Barry Gold
The relationship between N-nitrosodimethylamine metabolism and DNA methylation in isolated rat hepatocytes.
Carcinogenesis 1996;17(5):1127-34.
1996: L Encell; D E Shuker; P G Foiles; Barry Gold
The in vitro methylation of DNA by a minor groove binding methyl sulfonate ester.
Chemical research in toxicology 1996;9(3):563-7.
1996: Fa-xian Chen; William J Bodell; G Liang; Barry Gold
Reaction of N-(2-chloroethyl)-N-nitrosoureas with DNA: effect of buffers on DNA adduction, cross-linking, and cytotoxicity.
Chemical research in toxicology 1996;9(1):208-14.
1995: G Liang; Peter Gannett; Barry Gold
The use of 2-hydroperoxytetrahydrofuran as a reagent to sequence cytosine and to probe non-Watson-Crick DNA structures.
Nucleic acids research 1995;23(4):713-9.
1993: R L Wurdeman; M C Douskey; Barry Gold
DNA methylation by N-methyl-N-nitrosourea: methylation pattern changes in single- and double-stranded DNA, and in DNA with mismatched or bulged guanines.
Nucleic acids research 1993;21(21):4975-80.
1993: Y Zhang; Fa-xian Chen; P Mehta; Barry Gold
Groove- and sequence-selective alkylation of DNA by sulfonate esters tethered to lexitropsins.
Biochemistry 1993;32(31):7954-65.
1993: Fa-xian Chen; Y Zhang; K M Church; William J Bodell; Barry Gold
DNA crosslinking, sister chromatid exchange and cytotoxicity of N-2-chloroethylnitrosoureas tethered to minor groove binding peptides.
Carcinogenesis 1993;14(5):935-40.
1992: T Wilson; M J Lewis; K L Cha; Barry Gold
The effect of ellagic acid on xenobiotic metabolism by cytochrome P-450IIE1 and nitrosodimethylamine mutagenicity.
Cancer letters 1992;61(2):129-34.
1991: Barry Gold; K M Church; R L Wurdeman; Y Zhang; Fa-xian Chen
Control over the sequence specificity of DNA alkylation: syntheses and reactions with 32P-end-labelled DNA of N-alkyl-N-nitrosoureas linked to minor groove binding lexitropsins.
IARC scientific publications 1991;(105):439-42.
1990: K M Church; R L Wurdeman; Y Zhang; Fa-xian Chen; Barry Gold
N-(2-chloroethyl)-N-nitrosoureas covalently bound to nonionic and monocationic lexitropsin dipeptides. Synthesis, DNA affinity binding characteristics, and reactions with 32P-end-labeled DNA.
Biochemistry 1990;29(29):6827-38.
1988: T Konakahara; R L Wurdeman; Barry Gold
Synthesis of an N-methyl-N-nitrosourea linked to a methidium chloride analogue and its reactions with 32P-end-labeled DNA.
Biochemistry 1988;27(23):8606-13.
1988: K M Church; Barry Gold
The role of nucleophilicity in the ratio of primary to secondary solute-derived products in the decomposition of (1-acetoxypropyl)propylnitrosamine.
Chemical research in toxicology 1988;1(5):269-73.
1988: Barry Gold; G Brunk
The effect of pyrazole, phenobarbital, ethanol and 3-methylcholanthrene pretreatment on the in vivo and in vitro genotoxicity of N-nitrosopyrrolidine.
Carcinogenesis 1988;9(6):1001-5.
1988: R L Wurdeman; Barry Gold
The effect of DNA sequence, ionic strength, and cationic DNA affinity binders on the methylation of DNA by N-methyl-N-nitrosourea.
Chemical research in toxicology 1988;1(3):146-7.
1987: Rakesh Dixit; Barry Gold
Mechanism of inhibition of N-methyl-N-nitrosourea-induced mutagenicity and DNA binding by ellagic acid.
IARC scientific publications 1987;(84):197-9.
1986: Barry Gold; G Brunk
The effect of subchronic feeding of 1,1-dichloro-2,2-bis(4'-chlorophenyl)ethene (DDE) on its metabolism in mice.
Carcinogenesis 1986;7(7):1149-53.
1984: Barry Gold; G Brunk
A mechanistic study of the metabolism of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD) to 2,2-bis(p-chlorophenyl)acetic acid (DDA).
Biochemical pharmacology 1984;33(7):979-82.
1983: Barry Gold; G Brunk
Metabolism of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane, and 1-chloro-2,2-bis(p-chlorophenyl)ethene in the hamster.
Cancer research 1983;43(6):2644-7.
1982: Barry Gold; G Brunk
Metabolism of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane in the mouse.
Chemico-biological interactions 1982;41(3):327-39.
1981: Barry Gold; T Leuschen; G Brunk; R Gingell
Metabolism of a DDT metabolite via a chloroepoxide.
Chemico-biological interactions 1981;35(2):159-76.