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Daniel Goldberg

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TOP 3
Daniel E Goldberg
Complex nature of malaria parasite hemoglobin degradation.
Shalon E Babbitt; Simon A Cobbold; Christian Doerig; Clare Fennell; Eva S Istvan; Manuel Llinás; Lindsey Altenhofen; Daniel E Goldberg
Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state.
Daniel E Goldberg
Plasmodium protein export at higher PEXEL resolution.

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All Publications

2013: Daniel E Goldberg
Complex nature of malaria parasite hemoglobin degradation.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(14):5283-4.
2012: Shalon E Babbitt; Simon A Cobbold; Christian Doerig; Clare Fennell; Eva S Istvan; Manuel Llinás; Lindsey Altenhofen; Daniel E Goldberg
Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(47):E3278-87.
2012: Daniel E Goldberg
Plasmodium protein export at higher PEXEL resolution.
Cell host & microbe 2012;12(5):609-10.
2012: Daniel E Goldberg; Robert Siliciano; William R Jacobs
Outwitting evolution: fighting drug-resistant TB, malaria, and HIV.
Cell 2012;148(6):1271-83.
2012: Vasant Muralidharan; Anna Oksman; Priya Pal; Susan Lindquist; Daniel E Goldberg
Plasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers.
Nature communications 2012;3():1310.
2011: Vasant Muralidharan; Anna Oksman; Mari Iwamoto; Thomas J Wandless; Daniel E Goldberg
Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tag.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(11):4411-6.
2011: Eva S Istvan; Neekesh V Dharia; Selina Elisabeth Ruth Bopp; Ilya Y Gluzman; Elizabeth A Winzeler; Daniel E Goldberg
Validation of isoleucine utilization targets in Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(4):1627-32.
2011: Daniel E Goldberg; Chris J Janse; Alan F Cowman; Andrew P Waters
Has the time come for us to complement our malaria parasites?
Trends in parasitology 2011;27(1):1-2.
2010: Daniel E Goldberg; Alan F Cowman
Moving in and renovating: exporting proteins from Plasmodium into host erythrocytes.
Nature reviews. Microbiology 2010;8(9):617-21.
2010: Ilaria Russo; Shalon Babbitt; Vasant Muralidharan; Tamira Butler; Anna Oksman; Daniel E Goldberg
Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte.
Nature 2010;463(7281):632-6.
2009: Ilaria Russo; Anna Oksman; Daniel E Goldberg
Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus.
Molecular microbiology 2009;72(1):229-45.
2009: Ilaria Russo; Anna Oksman; Barbara Vaupel; Daniel E Goldberg
A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1554-9.
2008: Scott E Harpstrite; Silvia D Collins; Anna Oksman; Daniel E Goldberg; Vijay Sharma
Synthesis, characterization, and antimalarial activity of novel schiff-base-phenol and naphthalene-amine ligands.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2008;4(4):392-5.
2008: Mark E Drew; Ritu Banerjee; Eric W Uffman; Scott Gilbertson; Philip J Rosenthal; Daniel E Goldberg
Plasmodium food vacuole plasmepsins are activated by falcipains.
The Journal of biological chemistry 2008;283(19):12870-6.
2007: Christopher M Armstrong; Daniel E Goldberg
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum.
Nature methods 2007;4(12):1007-9.
2007: Marisa Ponpuak; Michael Klemba; Mehea Park; Ilya Y Gluzman; Gayle K Lamppa; Daniel E Goldberg
A role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplast.
Molecular microbiology 2007;63(2):314-34.
2006: Jun Liu; Eva S Istvan; Ilya Y Gluzman; Julia Gross; Daniel E Goldberg
Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(23):8840-5.
2006: Sunil Parikh; Jun Liu; Puran S Sijwali; Jiri Gut; Daniel E Goldberg; Philip J Rosenthal
Antimalarial effects of human immunodeficiency virus type 1 protease inhibitors differ from those of the aspartic protease inhibitor pepstatin.
Antimicrobial agents and chemotherapy 2006;50(6):2207-9.
2005: Michael Klemba; Daniel E Goldberg
Characterization of plasmepsin V, a membrane-bound aspartic protease homolog in the endoplasmic reticulum of Plasmodium falciparum.
Molecular and biochemical parasitology 2005;143(2):183-91.
2005: Sunil Parikh; Jiri Gut; Eva Istvan; Daniel E Goldberg; Diane V Havlir; Philip J Rosenthal
Antimalarial activity of human immunodeficiency virus type 1 protease inhibitors.
Antimicrobial agents and chemotherapy 2005;49(7):2983-5.
2005: Joseph A Ocheskey; Scott E Harpstrite; Anna Oksman; Daniel E Goldberg; Vijay Sharma
Metalloantimalarials: synthesis and characterization of a novel agent possessing activity against Plasmodium falciparum.
Chemical communications (Cambridge, England) 2005;(12):1622-4.
2005: Eva S Istvan; Daniel E Goldberg
Distal substrate interactions enhance plasmepsin activity.
The Journal of biological chemistry 2005;280(8):6890-6.
2005: Jun Liu; Ilya Y Gluzman; Mark E Drew; Daniel E Goldberg
The role of Plasmodium falciparum food vacuole plasmepsins.
The Journal of biological chemistry 2005;280(2):1432-7.
2005: Daniel E Goldberg
Hemoglobin degradation.
Current topics in microbiology and immunology 2005;295():275-91.
2004: Michael Klemba; Ilya Y Gluzman; Daniel E Goldberg
A Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradation.
The Journal of biological chemistry 2004;279(41):43000-7.
2004: Puran S Sijwali; Kentaro Kato; Karl Boynton Seydel; Jiri Gut; Julie Lehman; Michael Klemba; Daniel E Goldberg; Louis H Miller; Philip J Rosenthal
Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(23):8721-6.
2004: Michael Klemba; Wandy L Beatty; Ilya Y Gluzman; Daniel E Goldberg
Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum.
The Journal of cell biology 2004;164(1):47-56.
2003: Christina E Murata; Daniel E Goldberg
Plasmodium falciparum falcilysin: a metalloprotease with dual specificity.
The Journal of biological chemistry 2003;278(39):38022-8.
2003: Ritu Banerjee; Susan E Francis; Daniel E Goldberg
Food vacuole plasmepsins are processed at a conserved site by an acidic convertase activity in Plasmodium falciparum.
Molecular and biochemical parasitology 2003;129(2):157-65.
2003: Scott E Harpstrite; Alicia A Beatty; Silvia D Collins; Anna Oksman; Daniel E Goldberg; Vijay Sharma
Metalloantimalarials: targeting of P. falciparum strains with novel iron(III) and gallium(III) complexes of an amine phenol ligand.
Inorganic chemistry 2003;42(7):2294-300.
2003: Joseph A Ocheskey; Valery R Polyakov; Scott E Harpstrite; Anna Oksman; Daniel E Goldberg; David Piwnica-Worms; Vijay Sharma
Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains.
Journal of inorganic biochemistry 2003;93(3-4):265-70.
2002: Kristin M Brinner; Jin Mi Kim; Hiromu Habashita; Ilya Y Gluzman; Daniel E Goldberg; Jonathan A Ellman
Novel and potent anti-malarial agents.
Bioorganic & medicinal chemistry 2002;10(11):3649-61.
2002: Clara Y H Choi; Eric L Schneider; Jin M Kim; Ilya Y Gluzman; Daniel E Goldberg; Jonathan A Ellman; Michael A Marletta
Interference with heme binding to histidine-rich protein-2 as an antimalarial strategy.
Chemistry & biology 2002;9(8):881-9.
2002: Daniel E Goldberg
Parasitology. When the host is smarter than the parasite.
Science (New York, N.Y.) 2002;296(5567):482-3.
2002: Ritu Banerjee; Jun Liu; Wandy L Beatty; Lorraine Pelosof; Michael Klemba; Daniel E Goldberg
Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):990-5.
2002: Michael Klemba; Daniel E Goldberg
Biological roles of proteases in parasitic protozoa.
Annual review of biochemistry 2002;71():275-305.
2001: C B Mamoun; Daniel E Goldberg
Plasmodium protein phosphatase 2C dephosphorylates translation elongation factor 1beta and inhibits its PKC-mediated nucleotide exchange activity in vitro.
Molecular microbiology 2001;39(4):973-81.
2001: B L Salmon; A Oksman; Daniel E Goldberg
Malaria parasite exit from the host erythrocyte: a two-step process requiring extraerythrocytic proteolysis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):271-6.
2000: C B Mamoun; Ilya Y Gluzman; Stephen M Beverley; Daniel E Goldberg
Transposition of the Drosophila element mariner within the human malaria parasite Plasmodium falciparum.
Molecular and biochemical parasitology 2000;110(2):405-7.
1999: K K Eggleson; K L Duffin; Daniel E Goldberg
Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum.
The Journal of biological chemistry 1999;274(45):32411-7.
1999: Zhicheng Xia; Wei Zhang; Bao D Nguyen; Gerd N La Mar; A P Kloek; Daniel E Goldberg
1H NMR investigation of the distal hydrogen bonding network and ligand tilt in the cyanomet complex of oxygen-avid Ascaris suum hemoglobin.
The Journal of biological chemistry 1999;274(45):31819-26.
1999: D M Minning; Andrew J Gow; Joseph Bonaventura; Rod D Braun; Mark Dewhirst; Daniel E Goldberg; Jonathan S Stamler
Ascaris haemoglobin is a nitric oxide-activated 'deoxygenase'.
Nature 1999;401(6752):497-502.
1999: C B Mamoun; R Truong; Ilya Y Gluzman; N S Akopyants; A Oksman; Daniel E Goldberg
Transfer of genes into Plasmodium falciparum by polyamidoamine dendrimers.
Molecular and biochemical parasitology 1999;103(1):117-21.
1999: C B Mamoun; Ilya Y Gluzman; Sophie Goyard; Stephen M Beverley; Daniel E Goldberg
A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8716-20.
1999: T S Haque; A Geoffrey Skillman; C E Lee; Hiromu Habashita; Ilya Y Gluzman; Todd J A Ewing; Daniel E Goldberg; Irwin D Kuntz; Jonathan A Ellman
Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II.
Journal of medicinal chemistry 1999;42(8):1428-40.
1998: M J Crawford; Daniel E Goldberg
Regulation of the Salmonella typhimurium flavohemoglobin gene. A new pathway for bacterial gene expression in response to nitric oxide.
The Journal of biological chemistry 1998;273(51):34028-32.
1998: D M Minning; Daniel E Goldberg
Determinants of Ascaris hemoglobin octamer formation.
The Journal of biological chemistry 1998;273(49):32644-9.
1998: CD Carroll; T O Johnson; S Tao; G Lauri; Mark Orlowski; Ilya Y Gluzman; Daniel E Goldberg; Roland E Dolle
Evaluation of a structure-based statine cyclic diamino amide encoded combinatorial library against plasmepsin II and cathepsin D.
Bioorganic & medicinal chemistry letters 1998;8(22):3203-6.
1998: CD Carroll; H Patel; T O Johnson; T Guo; Mark Orlowski; Z M He; C L Cavallaro; J Guo; Anna Oksman; Ilya Y Gluzman; J Connelly; Daniel Chelsky; Daniel E Goldberg; Roland E Dolle
Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library.
Bioorganic & medicinal chemistry letters 1998;8(17):2315-20.
1998: M J Crawford; Daniel E Goldberg
Role for the Salmonella flavohemoglobin in protection from nitric oxide.
The Journal of biological chemistry 1998;273(20):12543-7.
1998: C B Mamoun; David Sullivan; R Banerjee; Daniel E Goldberg
Identification and characterization of an unusual double serine/threonine protein phosphatase 2C in the malaria parasite Plasmodium falciparum.
The Journal of biological chemistry 1998;273(18):11241-7.
1997: K A Kolakovich; Ilya Y Gluzman; K L Duffin; Daniel E Goldberg
Generation of hemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptide transport in amino acid production.
Molecular and biochemical parasitology 1997;87(2):123-35.
1997: SE Francis; R Banerjee; Daniel E Goldberg
Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II.
The Journal of biological chemistry 1997;272(23):14961-8.
1997: Daniel E Goldberg; Vijay Sharma; Anna Oksman; Ilya Y Gluzman; Thomas E Wellems; David Piwnica-Worms
Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes.
The Journal of biological chemistry 1997;272(10):6567-72.
1997: R M Truong; SE Francis; Debopam Chakrabarti; Daniel E Goldberg
Cloning and characterization of Plasmodium falciparum ADP-ribosylation factor and factor-like genes.
Molecular and biochemical parasitology 1997;84(2):247-53.
1997: SE Francis; David Sullivan; Daniel E Goldberg
Hemoglobin metabolism in the malaria parasite Plasmodium falciparum.
Annual review of microbiology 1997;51():97-123.
1996: David Sullivan; Y M Ayala; Daniel E Goldberg
An unexpected 5' untranslated intron in the P. falciparum genes for histidine-rich proteins II and III.
Molecular and biochemical parasitology 1996;83(2):247-51.
1996: S E Francis; Ilya Y Gluzman; Anna Oksman; D Banerjee; Daniel E Goldberg
Characterization of native falcipain, an enzyme involved in Plasmodium falciparum hemoglobin degradation.
Molecular and biochemical parasitology 1996;83(2):189-200.
1996: David Sullivan; Ilya Y Gluzman; David G Russell; Daniel E Goldberg
On the molecular mechanism of chloroquine's antimalarial action.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11865-70.
1996: A M Silva; A Y Lee; Sergei V Gulnik; P Maier; J Collins; TN Bhat; P J Collins; R E Cachau; Kathryn E Luker; Ilya Y Gluzman; S E Francis; Anna Oksman; Daniel E Goldberg; John W Erickson
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10034-9.
1996: A P Kloek; James P McCarter; R A Setterquist; T Schedl; Daniel E Goldberg
Caenorhabditis globin genes: rapid intronic divergence contrasts with conservation of silent exonic sites.
Journal of molecular evolution 1996;43(2):101-8.
1996: Kathryn E Luker; S E Francis; Ilya Y Gluzman; Daniel E Goldberg
Kinetic analysis of plasmepsins I and II aspartic proteases of the Plasmodium falciparum digestive vacuole.
Molecular and biochemical parasitology 1996;79(1):71-8.
1996: S Huang; J Huang; A P Kloek; Daniel E Goldberg; Joel Mitchel Friedman
Hydrogen bonding of tyrosine B10 to heme-bound oxygen in Ascaris hemoglobin. Direct evidence from UV resonance Raman spectroscopy.
The Journal of biological chemistry 1996;271(2):958-62.
1996: David Sullivan; Ilya Y Gluzman; Daniel E Goldberg
Plasmodium hemozoin formation mediated by histidine-rich proteins.
Science (New York, N.Y.) 1996;271(5246):219-22.
1995: D M Minning; A P Kloek; J Yang; F Scott Mathews; Daniel E Goldberg
Subunit interactions in Ascaris hemoglobin octamer formation.
The Journal of biological chemistry 1995;270(38):22248-53.
1995: J Yang; A P Kloek; Daniel E Goldberg; F Scott Mathews
The structure of Ascaris hemoglobin domain I at 2.2 A resolution: molecular features of oxygen avidity.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4224-8.
1995: M J Crawford; D R Sherman; Daniel E Goldberg
Regulation of Saccharomyces cerevisiae flavohemoglobin gene expression.
The Journal of biological chemistry 1995;270(12):6991-6.
1995: Daniel E Goldberg
The enigmatic oxygen-avid hemoglobin of Ascaris.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(2):177-82.
1994: Ilya Y Gluzman; S E Francis; Anna Oksman; C E Smith; K L Duffin; Daniel E Goldberg
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway.
The Journal of clinical investigation 1994;93(4):1602-8.
1994: A P Kloek; J Yang; F Scott Mathews; C Frieden; Daniel E Goldberg
The tyrosine B10 hydroxyl is crucial for oxygen avidity of Ascaris hemoglobin.
The Journal of biological chemistry 1994;269(4):2377-9.
1994: S E Francis; Ilya Y Gluzman; Anna Oksman; A Knickerbocker; R Mueller; M L Bryant; D R Sherman; David G Russell; Daniel E Goldberg
Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.
The EMBO journal 1994;13(2):306-17.
1993: A P Kloek; J Yang; F Scott Mathews; Daniel E Goldberg
Expression, characterization, and crystallization of oxygen-avid Ascaris hemoglobin domains.
The Journal of biological chemistry 1993;268(24):17669-71.
1993: A P Kloek; D R Sherman; Daniel E Goldberg
Novel gene structure and evolutionary context of Caenorhabditis elegans globin.
Gene 1993;129(2):215-21.
1992: D R Sherman; B Guinn; M M Perdok; Daniel E Goldberg
Components of sterol biosynthesis assembled on the oxygen-avid hemoglobin of Ascaris.
Science (New York, N.Y.) 1992;258(5090):1930-2.
1992: D R Sherman; A P Kloek; B R Krishnan; B Guinn; Daniel E Goldberg
Ascaris hemoglobin gene: plant-like structure reflects the ancestral globin gene.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11696-700.
1992: Daniel E Goldberg
Plasmodial hemoglobin degradation: an ordered pathway in a specialized organelle.
Infectious agents and disease 1992;1(4):207-11.