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Daniel Goldberg
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Research Profile (preview)
Living Beings
Chemicals & Drugs
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Anatomy
Procedures
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Network (preview)
22
Gluzman, Ilya
10
Oksman, Anna
7
Klemba, Michael
5
Sullivan, David
5
Sharma, Vijay
4
Harpstrite, Scott
4
Mathews, Scott
3
Francis, SE
3
Ellman, Jonathan
3
Rosenthal, Philip
3
Gut, Jiri
3
Russo, Ilaria
2
Piwnica-Worms, David
2
Carroll, CD
2
Parikh, Sunil
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All Publications
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2010: Goldberg Daniel E; Cowman Alan F
Moving in and renovating: exporting proteins from Plasmodium into host erythrocytes.
Nature reviews. Microbiology 2010;8(9):617-21.
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2010: Russo Ilaria; Babbitt Shalon; Muralidharan Vasant; Butler Tamira; Oksman Anna; Goldberg Daniel E
Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte.
Nature 2010;463(7281):632-6.
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2009: Russo Ilaria; Oksman Anna; Goldberg Daniel E
Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus.
Molecular microbiology 2009;72(1):229-45.
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2009: Russo Ilaria; Oksman Anna; Vaupel Barbara; Goldberg Daniel E
A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1554-9.
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2008: Harpstrite Scott E; Collins Silvia D; Oksman Ana; Goldberg Daniel E; Sharma Vijay
Synthesis, characterization, and antimalarial activity of novel schiff-base-phenol and naphthalene-amine ligands.
Medicinal chemistry (Shariqah (United Arab Emirates)) 2008;4(4):392-5.
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2008: Drew Mark E; Banerjee Ritu; Uffman Eric W; Gilbertson Scott; Rosenthal Philip J; Goldberg Daniel E
Plasmodium food vacuole plasmepsins are activated by falcipains.
The Journal of biological chemistry 2008;283(19):12870-6.
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2007: Armstrong Christopher M; Goldberg Daniel E
An FKBP destabilization domain modulates protein levels in Plasmodium falciparum.
Nature methods 2007;4(12):1007-9.
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2007: Ponpuak Marisa; Klemba Michael; Park Mehea; Gluzman Ilya Y; Lamppa Gayle K; Goldberg Daniel E
A role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplast.
Molecular microbiology 2007;63(2):314-34.
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2006: Liu Jun; Istvan Eva S; Gluzman Ilya Y; Gross Julia; Goldberg Daniel E
Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(23):8840-5.
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2006: Parikh Sunil; Liu Jun; Sijwali Puran; Gut Jiri; Goldberg Daniel E; Rosenthal Philip J
Antimalarial effects of human immunodeficiency virus type 1 protease inhibitors differ from those of the aspartic protease inhibitor pepstatin.
Antimicrobial agents and chemotherapy 2006;50(6):2207-9.
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2005: Klemba Michael; Goldberg Daniel E
Characterization of plasmepsin V, a membrane-bound aspartic protease homolog in the endoplasmic reticulum of Plasmodium falciparum.
Molecular and biochemical parasitology 2005;143(2):183-91.
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2005: Parikh Sunil; Gut Jiri; Istvan Eva; Goldberg Daniel E; Havlir Diane V; Rosenthal Philip J
Antimalarial activity of human immunodeficiency virus type 1 protease inhibitors.
Antimicrobial agents and chemotherapy 2005;49(7):2983-5.
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2005: Ocheskey Joseph A; Harpstrite Scott E; Oksman Anna; Goldberg Daniel E; Sharma Vijay
Metalloantimalarials: synthesis and characterization of a novel agent possessing activity against Plasmodium falciparum.
Chemical communications (Cambridge, England) 2005;(12):1622-4.
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2005: Istvan Eva S; Goldberg Daniel E
Distal substrate interactions enhance plasmepsin activity.
The Journal of biological chemistry 2005;280(8):6890-6.
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2005: Liu Jun; Gluzman Ilya Y; Drew Mark E; Goldberg Daniel E
The role of Plasmodium falciparum food vacuole plasmepsins.
The Journal of biological chemistry 2005;280(2):1432-7.
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2005: Goldberg D E
Hemoglobin degradation.
Current topics in microbiology and immunology 2005;295():275-91.
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2004: Klemba Michael; Gluzman Ilya; Goldberg Daniel E
A Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradation.
The Journal of biological chemistry 2004;279(41):43000-7.
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2004: Sijwali Puran S; Kato Kentaro; Seydel Karl B; Gut Jiri; Lehman Julie; Klemba Michael; Goldberg Daniel E; Miller Louis H; Rosenthal Philip J
Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(23):8721-6.
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2004: Klemba Michael; Beatty Wandy; Gluzman Ilya; Goldberg Daniel E
Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum.
The Journal of cell biology 2004;164(1):47-56.
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2003: Murata Christina E; Goldberg Daniel E
Plasmodium falciparum falcilysin: a metalloprotease with dual specificity.
The Journal of biological chemistry 2003;278(39):38022-8.
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2003: Banerjee Ritu; Francis Susan E; Goldberg Daniel E
Food vacuole plasmepsins are processed at a conserved site by an acidic convertase activity in Plasmodium falciparum.
Molecular and biochemical parasitology 2003;129(2):157-65.
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2003: Harpstrite Scott E; Beatty Alicia A; Collins Silvia D; Oksman Anna; Goldberg Daniel E; Sharma Vijay
Metalloantimalarials: targeting of P. falciparum strains with novel iron(III) and gallium(III) complexes of an amine phenol ligand.
Inorganic chemistry 2003;42(7):2294-300.
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2003: Ocheskey Joseph A; Polyakov Valery R; Harpstrite Scott E; Oksman Anna; Goldberg Daniel E; Piwnica-Worms David; Sharma Vijay
Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains.
Journal of inorganic biochemistry 2003;93(3-4):265-70.
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2002: Brinner Kristin M; Mi Kim Jin; Habashita Hiromu; Gluzman Ilya Y; Goldberg Daniel E; Ellman Jonathan A
Novel and potent anti-malarial agents.
Bioorganic & medicinal chemistry 2002;10(11):3649-61.
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2002: Choi Clara Y H; Schneider Eric L; Kim Jin M; Gluzman Ilya Y; Goldberg Daniel E; Ellman Jonathan A; Marletta Michael A
Interference with heme binding to histidine-rich protein-2 as an antimalarial strategy.
Chemistry & biology 2002;9(8):881-9.
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2002: Goldberg Daniel E
Parasitology. When the host is smarter than the parasite.
Science (New York, N.Y.) 2002;296(5567):482-3.
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2002: Banerjee Ritu; Liu Jun; Beatty Wandy; Pelosof Lorraine; Klemba Michael; Goldberg Daniel E
Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):990-5.
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2002: Klemba Michael; Goldberg Daniel E
Biological roles of proteases in parasitic protozoa.
Annual review of biochemistry 2002;71():275-305.
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2001: Mamoun C B; Goldberg D E
Plasmodium protein phosphatase 2C dephosphorylates translation elongation factor 1beta and inhibits its PKC-mediated nucleotide exchange activity in vitro.
Molecular microbiology 2001;39(4):973-81.
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2001: Salmon B L; Oksman A; Goldberg D E
Malaria parasite exit from the host erythrocyte: a two-step process requiring extraerythrocytic proteolysis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):271-6.
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2000: Mamoun C B; Gluzman I Y; Beverley S M; Goldberg D E
Transposition of the Drosophila element mariner within the human malaria parasite Plasmodium falciparum.
Molecular and biochemical parasitology 2000;110(2):405-7.
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1999: Eggleson K K; Duffin K L; Goldberg D E
Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum.
The Journal of biological chemistry 1999;274(45):32411-7.
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1999: Xia Z; Zhang W; Nguyen B D; Mar G N; Kloek A P; Goldberg D E
1H NMR investigation of the distal hydrogen bonding network and ligand tilt in the cyanomet complex of oxygen-avid Ascaris suum hemoglobin.
The Journal of biological chemistry 1999;274(45):31819-26.
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1999: Minning D M; Gow A J; Bonaventura J; Braun R; Dewhirst M; Goldberg D E; Stamler J S
Ascaris haemoglobin is a nitric oxide-activated 'deoxygenase'.
Nature 1999;401(6752):497-502.
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1999: Mamoun C B; Truong R; Gluzman I; Akopyants N S; Oksman A; Goldberg D E
Transfer of genes into Plasmodium falciparum by polyamidoamine dendrimers.
Molecular and biochemical parasitology 1999;103(1):117-21.
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1999: Mamoun C B; Gluzman I Y; Goyard S; Beverley S M; Goldberg D E
A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8716-20.
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1999: Haque T S; Skillman A G; Lee C E; Habashita H; Gluzman I Y; Ewing T J; Goldberg D E; Kuntz I D; Ellman J A
Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II.
Journal of medicinal chemistry 1999;42(8):1428-40.
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1998: Crawford M J; Goldberg D E
Regulation of the Salmonella typhimurium flavohemoglobin gene. A new pathway for bacterial gene expression in response to nitric oxide.
The Journal of biological chemistry 1998;273(51):34028-32.
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1998: Minning D M; Goldberg D E
Determinants of Ascaris hemoglobin octamer formation.
The Journal of biological chemistry 1998;273(49):32644-9.
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1998: Carroll C D; Johnson T O; Tao S; Lauri G; Orlowski M; Gluzman I Y; Goldberg D E; Dolle R E
Evaluation of a structure-based statine cyclic diamino amide encoded combinatorial library against plasmepsin II and cathepsin D.
Bioorganic & medicinal chemistry letters 1998;8(22):3203-6.
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1998: Carroll C D; Patel H; Johnson T O; Guo T; Orlowski M; He Z M; Cavallaro C L; Guo J; Oksman A; Gluzman I Y; Connelly J; Chelsky D; Goldberg D E; Dolle R E
Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library.
Bioorganic & medicinal chemistry letters 1998;8(17):2315-20.
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1998: Crawford M J; Goldberg D E
Role for the Salmonella flavohemoglobin in protection from nitric oxide.
The Journal of biological chemistry 1998;273(20):12543-7.
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1998: Mamoun C B; Sullivan D J; Banerjee R; Goldberg D E
Identification and characterization of an unusual double serine/threonine protein phosphatase 2C in the malaria parasite Plasmodium falciparum.
The Journal of biological chemistry 1998;273(18):11241-7.
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1997: Kolakovich K A; Gluzman I Y; Duffin K L; Goldberg D E
Generation of hemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptide transport in amino acid production.
Molecular and biochemical parasitology 1997;87(2):123-35.
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1997: Francis S E; Banerjee R; Goldberg D E
Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II.
The Journal of biological chemistry 1997;272(23):14961-8.
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1997: Goldberg D E; Sharma V; Oksman A; Gluzman I Y; Wellems T E; Piwnica-Worms D
Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes.
The Journal of biological chemistry 1997;272(10):6567-72.
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1997: Truong R M; Francis S E; Chakrabarti D; Goldberg D E
Cloning and characterization of Plasmodium falciparum ADP-ribosylation factor and factor-like genes.
Molecular and biochemical parasitology 1997;84(2):247-53.
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1997: Francis S E; Sullivan D J; Goldberg D E
Hemoglobin metabolism in the malaria parasite Plasmodium falciparum.
Annual review of microbiology 1997;51():97-123.
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1996: Sullivan D J; Ayala Y M; Goldberg D E
An unexpected 5' untranslated intron in the P. falciparum genes for histidine-rich proteins II and III.
Molecular and biochemical parasitology 1996;83(2):247-51.
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1996: Francis S E; Gluzman I Y; Oksman A; Banerjee D; Goldberg D E
Characterization of native falcipain, an enzyme involved in Plasmodium falciparum hemoglobin degradation.
Molecular and biochemical parasitology 1996;83(2):189-200.
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1996: Sullivan D J; Gluzman I Y; Russell D G; Goldberg D E
On the molecular mechanism of chloroquine's antimalarial action.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11865-70.
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1996: Silva A M; Lee A Y; Gulnik S V; Maier P; Collins J; Bhat T N; Collins P J; Cachau R E; Luker K E; Gluzman I Y; Francis S E; Oksman A; Goldberg D E; Erickson J W
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10034-9.
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1996: Kloek A P; McCarter J P; Setterquist R A; Schedl T; Goldberg D E
Caenorhabditis globin genes: rapid intronic divergence contrasts with conservation of silent exonic sites.
Journal of molecular evolution 1996;43(2):101-8.
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1996: Luker K E; Francis S E; Gluzman I Y; Goldberg D E
Kinetic analysis of plasmepsins I and II aspartic proteases of the Plasmodium falciparum digestive vacuole.
Molecular and biochemical parasitology 1996;79(1):71-8.
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1996: Huang S; Huang J; Kloek A P; Goldberg D E; Friedman J M
Hydrogen bonding of tyrosine B10 to heme-bound oxygen in Ascaris hemoglobin. Direct evidence from UV resonance Raman spectroscopy.
The Journal of biological chemistry 1996;271(2):958-62.
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1996: Sullivan D J; Gluzman I Y; Goldberg D E
Plasmodium hemozoin formation mediated by histidine-rich proteins.
Science (New York, N.Y.) 1996;271(5246):219-22.
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1995: Minning D M; Kloek A P; Yang J; Mathews F S; Goldberg D E
Subunit interactions in Ascaris hemoglobin octamer formation.
The Journal of biological chemistry 1995;270(38):22248-53.
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1995: Yang J; Kloek A P; Goldberg D E; Mathews F S
The structure of Ascaris hemoglobin domain I at 2.2 A resolution: molecular features of oxygen avidity.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4224-8.
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1995: Crawford M J; Sherman D R; Goldberg D E
Regulation of Saccharomyces cerevisiae flavohemoglobin gene expression.
The Journal of biological chemistry 1995;270(12):6991-6.
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1995: Goldberg D E
The enigmatic oxygen-avid hemoglobin of Ascaris.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(2):177-82.
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1994: Gluzman I Y; Francis S E; Oksman A; Smith C E; Duffin K L; Goldberg D E
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway.
The Journal of clinical investigation 1994;93(4):1602-8.
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1994: Francis S E; Gluzman I Y; Oksman A; Knickerbocker A; Mueller R; Bryant M L; Sherman D R; Russell D G; Goldberg D E
Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.
The EMBO journal 1994;13(2):306-17.
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1994: Kloek A P; Yang J; Mathews F S; Frieden C; Goldberg D E
The tyrosine B10 hydroxyl is crucial for oxygen avidity of Ascaris hemoglobin.
The Journal of biological chemistry 1994;269(4):2377-9.
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1993: Kloek A P; Yang J; Mathews F S; Goldberg D E
Expression, characterization, and crystallization of oxygen-avid Ascaris hemoglobin domains.
The Journal of biological chemistry 1993;268(24):17669-71.
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1993: Kloek A P; Sherman D R; Goldberg D E
Novel gene structure and evolutionary context of Caenorhabditis elegans globin.
Gene 1993;129(2):215-21.
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1992: Sherman D R; Kloek A P; Krishnan B R; Guinn B; Goldberg D E
Ascaris hemoglobin gene: plant-like structure reflects the ancestral globin gene.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11696-700.
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1992: Sherman D R; Guinn B; Perdok M M; Goldberg D E
Components of sterol biosynthesis assembled on the oxygen-avid hemoglobin of Ascaris.
Science (New York, N.Y.) 1992;258(5090):1930-2.
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1992: Goldberg D E
Plasmodial hemoglobin degradation: an ordered pathway in a specialized organelle.
Infectious agents and disease 1992;1(4):207-11.
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