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Itzhak Goldberg

Research Profile

Chemicals & Drugs

Anatomy

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Physiology

Genes & Molecular Sequences

BRCA1 Genes

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Publications

TOP 3
J Xu; M Gao; Saijun Fan; Qinghui Meng; Itzhak D Goldberg; Roger Abounader; Habtom W Ressom; John Laterra; Eliot M Rosen
Effect of Akt inhibition on scatter factor-regulated gene expression in DU-145 human prostate cancer cells.
Kejin Wu; Zhiwei Quan; Ziyi Weng; Fangming Li; Yichu Zhang; Xiaohong Yao; Yiding Chen; Daniel Budman; Itzhak D Goldberg; Yuenian Shi
Expression of neuronal protein synuclein gamma gene as a novel marker for breast cancer prognosis.
Yongxian Ma; Ren-Qi Yuan; Saijun Fan; Changyan Hu; Itzhak D Goldberg; John Laterra; Eliot M Rosen
Identification of genes that modulate sensitivity of U373MG glioblastoma cells to cis-platinum.

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2007: J Xu; M Gao; Saijun Fan; Qinghui Meng; Itzhak D Goldberg; Roger Abounader; Habtom W Ressom; John Laterra; Eliot M Rosen
Effect of Akt inhibition on scatter factor-regulated gene expression in DU-145 human prostate cancer cells.
Oncogene 2007;26(20):2925-38.
2007: Kejin Wu; Zhiwei Quan; Ziyi Weng; Fangming Li; Yichu Zhang; Xiaohong Yao; Yiding Chen; Daniel Budman; Itzhak D Goldberg; Yuenian Shi
Expression of neuronal protein synuclein gamma gene as a novel marker for breast cancer prognosis.
Breast cancer research and treatment 2007;101(3):259-67.
2006: Yongxian Ma; Ren-Qi Yuan; Saijun Fan; Changyan Hu; Itzhak D Goldberg; John Laterra; Eliot M Rosen
Identification of genes that modulate sensitivity of U373MG glioblastoma cells to cis-platinum.
Anti-cancer drugs 2006;17(7):733-51.
2005: Yong Xian Ma; York Tomita; Saijun Fan; Kongming Wu; Youzhi Tong; Zeguo Zhao; Liang-Nian Song; Itzhak D Goldberg; Eliot M Rosen
Structural determinants of the BRCA1 : estrogen receptor interaction.
Oncogene 2005;24(11):1831-46.
2005: Saijun Fan; Min Gao; Qinghui Meng; John Laterra; Marc Symons; Sal Coniglio; Richard G Pestell; Itzhak D Goldberg; Eliot M Rosen
Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection.
Oncogene 2005;24(10):1749-66.
2004: Insoo Bae; Saijun Fan; Qinghui Meng; Jeong-Keun Rih; Hee Jong Kim; Hyo Jin Kang; Jingwen Xu; Itzhak D Goldberg; Anil K Jaiswal; Eliot M Rosen
BRCA1 induces antioxidant gene expression and resistance to oxidative stress.
Cancer research 2004;64(21):7893-909.
2004: Yangfu Jiang; Yiliang Ellie Liu; Itzhak D Goldberg; Yuenian Shi
Gamma synuclein, a novel heat-shock protein-associated chaperone, stimulates ligand-dependent estrogen receptor alpha signaling and mammary tumorigenesis.
Cancer research 2004;64(13):4539-46.
2003: Jingbo Xiong; Saijun Fan; Qinghui Meng; Laura Schramm; Chenguang Wang; Boumedienne Bouzahza; Jinnian Zhou; Brian Zafonte; Itzhak D Goldberg; Bassem R Haddad; Richard G Pestell; Eliot M Rosen
BRCA1 inhibition of telomerase activity in cultured cells.
Molecular and cellular biology 2003;23(23):8668-90.
2003: Mingsheng Wang; Yiliang Ellie Liu; Itzhak D Goldberg; Yuenian Shi
Induction of mammary gland differentiation in transgenic mice by the fatty acid-binding protein MRG.
The Journal of biological chemistry 2003;278(47):47319-25.
2003: Eliot M Rosen; Saijun Fan; Richard G Pestell; Itzhak D Goldberg
BRCA1 in hormone-responsive cancers.
Trends in endocrinology and metabolism: TEM 2003;14(8):378-85.
2003: Yangfu Jiang; Yiliang Ellie Liu; AiPing Lu; Anu Gupta; Itzhak D Goldberg; Jingwen Liu; Yuenian Shi
Stimulation of estrogen receptor signaling by gamma synuclein.
Cancer research 2003;63(14):3899-903.
2003: Eliot M Rosen; Saijun Fan; Richard G Pestell; Itzhak D Goldberg
BRCA1 gene in breast cancer.
Journal of cellular physiology 2003;196(1):19-41.
2003: Kye-Im Jeon; Jeong-Keun Rih; Hee-Jeong Kim; Yong J Lee; Chi-Heum Cho; Itzhak D Goldberg; Eliot M Rosen; Insoo Bae
Pretreatment of indole-3-carbinol augments TRAIL-induced apoptosis in a prostate cancer cell line, LNCaP.
FEBS letters 2003;544(1-3):246-51.
2003: Yong Xian Ma; Saijun Fan; Jingbo Xiong; Ren-Qi Yuan; Qinghui Meng; Min Gao; Itzhak D Goldberg; Suzanne A Fuqua; Richard G Pestell; Eliot M Rosen
Role of BRCA1 in heat shock response.
Oncogene 2003;22(1):10-27.
2002: Yangfu Jiang; Itzhak D Goldberg; Yuenian Shi
Complex roles of tissue inhibitors of metalloproteinases in cancer.
Oncogene 2002;21(14):2245-52.
2002: Saijun Fan; Yong Xian Ma; Chenguang Wang; Ren-Qi Yuan; Qinghui Meng; Ji-An Wang; Michael R Erdos; Itzhak D Goldberg; Paul Webb; Peter J Kushner; Richard G Pestell; Eliot M Rosen
p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
Cancer research 2002;62(1):141-51.
2001: Min Gao; Saijun Fan; Itzhak D Goldberg; John Laterra; Richard N Kitsis; Eliot M Rosen
Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells.
The Journal of biological chemistry 2001;276(50):47257-65.
2001: Saijun Fan; R Yuan; Yong Xian Ma; Qinghui Meng; Itzhak D Goldberg; Eliot M Rosen
Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1.
Oncogene 2001;20(57):8215-35.
2001: R Yuan; Saijun Fan; M Achary; D M Stewart; Itzhak D Goldberg; Eliot M Rosen
Altered gene expression pattern in cultured human breast cancer cells treated with hepatocyte growth factor/scatter factor in the setting of DNA damage.
Cancer research 2001;61(21):8022-31.
2001: Saijun Fan; R Yuan; Yong Xian Ma; Jingbo Xiong; Qinghui Meng; Michael R Erdos; J N Zhao; Itzhak D Goldberg; Richard G Pestell; Eliot M Rosen
Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding.
Oncogene 2001;20(35):4827-41.
2001: Saijun Fan; Yong Xian Ma; Min Gao; Ren-Qi Yuan; Qinghui Meng; Itzhak D Goldberg; Eliot M Rosen
The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair.
Molecular and cellular biology 2001;21(15):4968-84.
2001: Mahmut Y Celiker; Mingsheng Wang; E Atsidaftos; X Liu; Yiliang Ellie Liu; Yangfu Jiang; Elsa Valderrama; Itzhak D Goldberg; Yuenian Shi
Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA.
Oncogene 2001;20(32):4337-43.
2001: Yangfu Jiang; Mingsheng Wang; Mahmut Y Celiker; Yiliang Ellie Liu; Qing-Xiang Amy Sang; Itzhak D Goldberg; Yuenian Shi
Stimulation of mammary tumorigenesis by systemic tissue inhibitor of matrix metalloproteinase 4 gene delivery.
Cancer research 2001;61(6):2365-70.
2001: Qing-hui Meng; Ren-Qi Yuan; Itzhak D Goldberg; Eliot M Rosen; Sai-jun Fan
BRCA1 is differentially expressed in human tumor cells.
Shi yan sheng wu xue bao 2001;34(1):55-64.
2001: Saijun Fan; Yong Xian Ma; Chenguang Wang; Ren-Qi Yuan; Qinghui Meng; Ji-An Wang; Michael R Erdos; Itzhak D Goldberg; P Webb; Peter J Kushner; Richard G Pestell; Eliot M Rosen
Role of direct interaction in BRCA1 inhibition of estrogen receptor activity.
Oncogene 2001;20(1):77-87.
2001: Eliot M Rosen; Saijun Fan; Itzhak D Goldberg
BRCA1 and prostate cancer.
Cancer investigation 2001;19(4):396-412.
2000: Q Meng; Fang Yuan; Itzhak D Goldberg; Eliot M Rosen; Karen Auborn; S Fan
Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells.
The Journal of nutrition 2000;130(12):2927-31.
2000: Mingsheng Wang; Yiliang Ellie Liu; J Ni; B Aygun; Itzhak D Goldberg; Yuenian Shi
Induction of mammary differentiation by mammary-derived growth inhibitor-related gene that interacts with an omega-3 fatty acid on growth inhibition of breast cancer cells.
Cancer research 2000;60(22):6482-7.
2000: Saijun Fan; Qinghui Meng; B Gao; J Grossman; M Yadegari; Itzhak D Goldberg; Eliot M Rosen
Alcohol stimulates estrogen receptor signaling in human breast cancer cell lines.
Cancer research 2000;60(20):5635-9.
2000: Q Meng; Itzhak D Goldberg; Eliot M Rosen; Saijun Fan
Inhibitory effects of Indole-3-carbinol on invasion and migration in human breast cancer cells.
Breast cancer research and treatment 2000;63(2):147-52.
2000: E M Rosen; Saijun Fan; Itzhak D Goldberg; S Rockwell
Biological basis of radiation sensitivity. Part 2: Cellular and molecular determinants of radiosensitivity.
Oncology (Williston Park, N.Y.) 2000;14(5):741-57; discussion 757-8, 761-6.
2000: Saijun Fan; Yong Xian Ma; Ji-An Wang; Ren-Qi Yuan; Qinghui Meng; Y Cao; John Laterra; Itzhak D Goldberg; Eliot M Rosen
The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3' kinase.
Oncogene 2000;19(18):2212-23.
2000: Eliot M Rosen; Saijun Fan; Itzhak D Goldberg; S Rockwell
Biological basis of radiation sensitivity. Part 1: Factors governing radiation tolerance.
Oncology (Williston Park, N.Y.) 2000;14(4):543-50.
2000: Qinghui Meng; Mei Qi; D Z Chen; R Yuan; Itzhak D Goldberg; Eliot M Rosen; Karen Auborn; Saijun Fan
Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexes.
Journal of molecular medicine (Berlin, Germany) 2000;78(3):155-65.
1999: R Yuan; Saijun Fan; Ji-An Wang; Qinghui Meng; Y Ma; D Schreiber; Itzhak D Goldberg; Eliot M Rosen
Coordinate alterations in the expression of BRCA1, BRCA2, p300, and Rad51 in response to genotoxic and other stresses in human prostate cancer cells.
The Prostate 1999;40(1):37-49.
1999: Saijun Fan; J Wang; R Yuan; Y Ma; Qinghui Meng; Michael R Erdos; Richard G Pestell; Fang Yuan; Karen Auborn; Itzhak D Goldberg; Eliot M Rosen
BRCA1 inhibition of estrogen receptor signaling in transfected cells.
Science (New York, N.Y.) 1999;284(5418):1354-6.
1999: G Xiao; Yiliang Ellie Liu; R Gentz; Q A Sang; J Ni; Itzhak D Goldberg; Yuenian Shi
Suppression of breast cancer growth and metastasis by a serpin myoepithelium-derived serine proteinase inhibitor expressed in the mammary myoepithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3700-5.
1999: Ji-An Wang; Saijun Fan; Ren-Qi Yuan; Yong Xian Ma; Qinghui Meng; Itzhak D Goldberg; Eliot M Rosen
Ultraviolet radiation down-regulates expression of the cell-cycle inhibitor p21WAF1/CIP1 in human cancer cells independently of p53.
International journal of radiation biology 1999;75(3):301-16.
1999: Eliot M Rosen; Saijun Fan; S Rockwell; Itzhak D Goldberg
The molecular and cellular basis of radiosensitivity: implications for understanding how normal tissues and tumors respond to therapeutic radiation.
Cancer investigation 1999;17(1):56-72.
1998: Saijun Fan; N F Twu; Ji-An Wang; Ren-Qi Yuan; JL Andres; Itzhak D Goldberg; Eliot M Rosen
Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to adriamycin and ultraviolet radiation.
International journal of cancer. Journal international du cancer 1998;77(4):600-9.
1998: Saijun Fan; Ji-An Wang; Ren-Qi Yuan; S Rockwell; JL Andres; A Zlatapolskiy; Itzhak D Goldberg; Eliot M Rosen
Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents.
Oncogene 1998;17(2):131-41.
1998: Saijun Fan; Ji-An Wang; Ren-Qi Yuan; Yong Xian Ma; Qinghui Meng; Michael R Erdos; Lawrence C Brody; Itzhak D Goldberg; Eliot M Rosen
BRCA1 as a potential human prostate tumor suppressor: modulation of proliferation, damage responses and expression of cell regulatory proteins.
Oncogene 1998;16(23):3069-82.
1998: JL Andres; Saijun Fan; G J Turkel; Ji-An Wang; N F Twu; Ren-Qi Yuan; Katrin Lamszus; Itzhak D Goldberg; Eliot M Rosen
Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents.
Oncogene 1998;16(17):2229-41.
1998: Katrin Lamszus; Nils Ole Schmidt; L Jin; John Laterra; David Zagzag; DL Way; Marlys H Witte; Martin Weinand; Itzhak D Goldberg; Manfred Westphal; Eliot M Rosen
Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells.
International journal of cancer. Journal international du cancer 1998;75(1):19-28.
1997: L Jin; Ren-Qi Yuan; Alexander Fuchs; Y Yao; A Joseph; R Schwall; S J Schnitt; A Guida; H M Hastings; JL Andres; G Turkel; Peter J Polverini; Itzhak D Goldberg; Eliot M Rosen
Expression of interleukin-1beta in human breast carcinoma.
Cancer 1997;80(3):421-34.
1997: John Laterra; M Nam; E Rosen; Jasti Sambasiva Rao; Katrin Lamszus; Itzhak D Goldberg; Peter V Johnston
Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo.
Laboratory investigation; a journal of technical methods and pathology 1997;76(4):565-77.
1997: Katrin Lamszus; L Jin; Alexander Fuchs; Yuenian Shi; S Chowdhury; Y Yao; Peter J Polverini; John Laterra; Itzhak D Goldberg; Eliot M Rosen
Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice.
Laboratory investigation; a journal of technical methods and pathology 1997;76(3):339-53.
1997: L Jin; Alexander Fuchs; S J Schnitt; Y Yao; A Joseph; Katrin Lamszus; M Park; Itzhak D Goldberg; Eliot M Rosen
Expression of scatter factor and c-met receptor in benign and malignant breast tissue.
Cancer 1997;79(4):749-60.
1997: Eliot M Rosen; Katrin Lamszus; John Laterra; Peter J Polverini; J S Rubin; Itzhak D Goldberg
HGF/SF in angiogenesis.
Ciba Foundation symposium 1997;212():215-26; discussion 227-9.
1997: E M Rosen; Itzhak D Goldberg
Regulation of angiogenesis by scatter factor.
EXS 1997;79():193-208.
1997: Eliot M Rosen; A Joseph; L Jin; Y Yao; M H Chau; Alexander Fuchs; L Gomella; H Hastings; Itzhak D Goldberg; Gary Weiss
Urinary and tissue levels of scatter factor in transitional cell carcinoma of bladder.
The Journal of urology 1997;157(1):72-8.
1996: Y Yao; L Jin; Alexander Fuchs; A Joseph; H M Hastings; Itzhak D Goldberg; Eliot M Rosen
Scatter factor protein levels in human breast cancers: clinicopathological and biological correlations.
The American journal of pathology 1996;149(5):1707-17.
1996: Katrin Lamszus; A Joseph; L Jin; Y Yao; S Chowdhury; Alexander Fuchs; Peter J Polverini; Itzhak D Goldberg; Eliot M Rosen
Scatter factor binds to thrombospondin and other extracellular matrix components.
The American journal of pathology 1996;149(3):805-19.
1996: Eliot M Rosen; John Laterra; A Joseph; L Jin; Alexander Fuchs; D Way; Marlys H Witte; Martin Weinand; Itzhak D Goldberg
Scatter factor expression and regulation in human glial tumors.
International journal of cancer. Journal international du cancer 1996;67(2):248-55.
1995: A Joseph; Gary Weiss; L Jin; Alexander Fuchs; S Chowdhury; P O'Shaugnessy; Itzhak D Goldberg; Eliot M Rosen
Expression of scatter factor in human bladder carcinoma.
Journal of the National Cancer Institute 1995;87(5):372-7.
1995: Eliot M Rosen; Itzhak D Goldberg
Scatter factor and angiogenesis.
Advances in cancer research 1995;67():257-79.
1994: Eliot M Rosen; A Joseph; L Jin; S Rockwell; Jack A Elias; J Knesel; J Wines; J McClellan; M J Kluger; Itzhak D Goldberg
Regulation of scatter factor production via a soluble inducing factor.
The Journal of cell biology 1994;127(1):225-34.
1994: Eliot M Rosen; J Knesel; Itzhak D Goldberg; L Jin; M Bhargava; A Joseph; R Zitnik; J Wines; M Kelley; S Rockwell
Scatter factor modulates the metastatic phenotype of the EMT6 mouse mammary tumor.
International journal of cancer. Journal international du cancer 1994;57(5):706-14.
1994: Y Li; M M Bhargava; A Joseph; L Jin; Eliot M Rosen; Itzhak D Goldberg
Effect of hepatocyte growth factor/scatter factor and other growth factors on motility and morphology of non-tumorigenic and tumor cells.
In vitro cellular & developmental biology. Animal 1994;30A(2):105-10.
1993: L Jin; Y Y Pang; A Joseph; Y Li; Eliot M Rosen; M M Bhargava; Itzhak D Goldberg
Rat placental hepatocyte growth factor/scatter factor: purification, characterization, and developmental regulation.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1993;204(1):75-80.
1993: Derrick S Grant; Hynda K Kleinman; Itzhak D Goldberg; M M Bhargava; B J Nickoloff; J L Kinsella; Peter J Polverini; Eliot M Rosen
Scatter factor induces blood vessel formation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1937-41.
1993: M M Bhargava; Y Li; A Joseph; L Jin; Eliot M Rosen; Itzhak D Goldberg
HGF-SF: effects on motility and morphology of normal and tumor cells.
EXS 1993;65():341-9.
1993: Eliot M Rosen; Derrick S Grant; Hynda K Kleinman; Itzhak D Goldberg; M M Bhargava; B J Nickoloff; J L Kinsella; Peter J Polverini
Scatter factor (hepatocyte growth factor) is a potent angiogenesis factor in vivo.
Symposia of the Society for Experimental Biology 1993;47():227-34.
1993: Eliot M Rosen; R J Zitnik; Jack A Elias; M M Bhargava; J Wines; Itzhak D Goldberg
The interaction of HGF-SF with other cytokines in tumor invasion and angiogenesis.
EXS 1993;65():301-10.
1992: A Joseph; M Bhargava; E Rosen; Itzhak D Goldberg
Binding of scatter factor to epithelial cell membrane protein: identification of its receptor.
Biochimica et biophysica acta 1992;1105(1):141-7.
1991: Eliot M Rosen; J Knesel; Itzhak D Goldberg
Scatter factor and its relationship to hepatocyte growth factor and met.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(11):603-7.
1991: Eliot M Rosen; Itzhak D Goldberg; D Liu; E Setter; M A Donovan; M Bhargava; Michael Reiss; Barry M Kacinski
Tumor necrosis factor stimulates epithelial tumor cell motility.
Cancer research 1991;51(19):5315-21.
1991: Eliot M Rosen; S Jaken; W Carley; P M Luckett; E Setter; M Bhargava; Itzhak D Goldberg
Regulation of motility in bovine brain endothelial cells.
Journal of cellular physiology 1991;146(2):325-35.
1991: Eliot M Rosen; D Grant; Hynda K Kleinman; S Jaken; M A Donovan; E Setter; P M Luckett; W Carley; M Bhargava; Itzhak D Goldberg
Scatter factor stimulates migration of vascular endothelium and capillary-like tube formation.
EXS 1991;59():76-88.
1991: M M Bhargava; Y Li; A Joseph; M Pendergast; R Hofmann; Eliot M Rosen; Itzhak D Goldberg
Purification, characterization and mechanism of action of scatter factor from human placenta.
EXS 1991;59():63-75.
1991: Eliot M Rosen; D Liu; E Setter; M Bhargava; Itzhak D Goldberg
Interleukin-6 stimulates motility of vascular endothelium.
EXS 1991;59():194-205.
1990: Eliot M Rosen; L Meromsky; E Setter; D W Vinter; Itzhak D Goldberg
Purified scatter factor stimulates epithelial and vascular endothelial cell migration.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1990;195(1):34-43.
1990: Eliot M Rosen; L Meromsky; E Setter; D W Vinter; Itzhak D Goldberg
Smooth muscle-derived factor stimulates mobility of human tumor cells.
Invasion & metastasis 1990;10(1):49-64.
1990: Eliot M Rosen; W Carley; Itzhak D Goldberg
Scatter factor regulates vascular endothelial cell motility.
Cancer investigation 1990;8(6):647-50.
1990: Eliot M Rosen; L Meromsky; E Setter; D W Vinter; Itzhak D Goldberg
Quantitation of cytokine-stimulated migration of endothelium and epithelium by a new assay using microcarrier beads.
Experimental cell research 1990;186(1):22-31.
1989: Eliot M Rosen; Itzhak D Goldberg
Protein factors which regulate cell motility.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1989;25(12):1079-87.
1989: Eliot M Rosen; D W Vinter; Itzhak D Goldberg
Hypertrophy of cultured bovine aortic endothelium following irradiation.
Radiation research 1989;117(3):395-408.
1989: Eliot M Rosen; Itzhak D Goldberg; Barry M Kacinski; T Buckholz; D W Vinter
Smooth muscle releases an epithelial cell scatter factor which binds to heparin.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1989;25(2):163-73.