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Barbara Ardelt

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Procedures

Flow Cytometry

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Rana pipiens

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Publications

TOP 3
Wojciech Ardelt; Barbara Ardelt; Zbigniew Darzynkiewicz
Ribonucleases as potential modalities in anticancer therapy.
Hong Zhao; Barbara Ardelt; Wojciech Ardelt; Kuslima Shogen; Zbigniew Darzynkiewicz
The cytotoxic ribonuclease onconase targets RNA interference (siRNA).
Masamichi Ita; H Dorota Halicka; Toshiki Tanaka; Akira Kurose; Barbara Ardelt; Kuslima Shogen; Zbigniew Darzynkiewicz
Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.

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All Publications

2009: Wojciech Ardelt; Barbara Ardelt; Zbigniew Darzynkiewicz
Ribonucleases as potential modalities in anticancer therapy.
European journal of pharmacology 2009;625(1-3):181-9.
2008: Hong Zhao; Barbara Ardelt; Wojciech Ardelt; Kuslima Shogen; Zbigniew Darzynkiewicz
The cytotoxic ribonuclease onconase targets RNA interference (siRNA).
Cell cycle (Georgetown, Tex.) 2008;7(20):3258-61.
2008: Masamichi Ita; H Dorota Halicka; Toshiki Tanaka; Akira Kurose; Barbara Ardelt; Kuslima Shogen; Zbigniew Darzynkiewicz
Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines.
Cancer biology & therapy 2008;7(7):1104-8.
2007: Barbara Ardelt; Wojciech Ardelt; Piotr Pozarowski; Jan Kunicki; Kuslima Shogen; Zbigniew Darzynkiewicz
Cytostatic and cytotoxic properties of Amphinase: a novel cytotoxic ribonuclease from Rana pipiens oocytes.
Cell cycle (Georgetown, Tex.) 2007;6(24):3097-102.
2007: Barbara Ardelt; Gloria Juan; P Burfeind; T Salomon; Joseph Wu; Tze-Chen Hsieh; X Li; R Sperry; Piotr Pozarowski; Kuslima Shogen; Wojciech Ardelt; Zbigniew Darzynkiewicz
Onconase, an anti-tumor ribonuclease suppresses intracellular oxidative stress.
International journal of oncology 2007;31(3):663-9.
2007: Cindy Schulenburg; Barbara Ardelt; Wojciech Ardelt; Ulrich Arnold; Kuslima Shogen; Renate Ulbrich-Hofmann; Zbigniew Darzynkiewicz
The interdependence between catalytic activity, conformational stability, and cytotoxicity of onconase.
Cancer biology & therapy 2007;6(8):1233-9.
2007: H Dorota Halicka; Barbara Ardelt; Kuslima Shogen; Zbigniew Darzynkiewicz
Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase.
International journal of oncology 2007;30(4):841-7.
2005: Kavita Jain; Uzzal Roy; Barbara Ardelt; U Murali Krishna; J R Falck; Piotr Pozarowski; Jan Kunicki; Zbigniew Darzynkiewicz; Michael Balazy
5E, 8Z, 11Z, 14Z-eicosatetraenoic acid, a novel trans isomer of arachidonic acid, causes G1 phase arrest and induces apoptosis of HL-60 cells.
International journal of oncology 2005;27(5):1177-85.
2004: Shwu Y Tsai; Barbara Ardelt; Tze-Chen Hsieh; Zbigniew Darzynkiewicz; Kuslima Shogen; Joseph Wu
Treatment of Jurkat acute T-lymphocytic leukemia cells by onconase (Ranpirnase) is accompanied by an altered nucleocytoplasmic distribution and reduced expression of transcription factor NF-kappaB.
International journal of oncology 2004;25(6):1745-52.
2003: Barbara Ardelt; Wojciech Ardelt; Zbigniew Darzynkiewicz
Cytotoxic ribonucleases and RNA interference (RNAi).
Cell cycle (Georgetown, Tex.) 2003;2(1):22-4.
2002: Jerzy Grabarek; Barbara Ardelt; Jan Kunicki; Zbigniew Darzynkiewicz
Detection of in situ activation of transglutaminase during apoptosis: correlation with the cell cycle phase by multiparameter flow and laser scanning cytometry.
Cytometry 2002;49(2):83-9.
2002: Jerzy Grabarek; Barbara Ardelt; Litong Du; Zbigniew Darzynkiewicz
Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase).
Experimental cell research 2002;278(1):61-71.
2002: S Y Tsai; Tze-Chen Hsieh; Barbara Ardelt; Zbigniew Darzynkiewicz; Joseph Wu
Combined effects of onconase and IFN-beta on proliferation, macromolecular syntheses and expression of STAT-1 in JCA-1 cancer cells.
International journal of oncology 2002;20(5):891-6.
2001: Wojciech Gorczyca; Piotr Smolewski; Jerzy Grabarek; Barbara Ardelt; M Ita; Myron R Melamed; Zbigniew Darzynkiewicz
Morphometry of nucleoli and expression of nucleolin analyzed by laser scanning cytometry in mitogenically stimulated lymphocytes.
Cytometry 2001;45(3):206-13.
2001: Barbara Ardelt; Jan Kunicki; Frank Traganos; Zbigniew Darzynkiewicz
Chlorophyllin protects cells from the cytostatic and cytotoxic effects of quinacrine mustard but not of nitrogen mustard.
International journal of oncology 2001;18(4):849-53.
1998: Gloria Juan; Barbara Ardelt; X Li; Stanislaw M Mikulski; Kuslima Shogen; Wojciech Ardelt; Abraham Mittelman; Zbigniew Darzynkiewicz
G1 arrest of U937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation.
Leukemia 1998;12(8):1241-8.
1998: A Deptala; H Dorota Halicka; Barbara Ardelt; Wojciech Ardelt; Stanislaw M Mikulski; Kuslima Shogen; Zbigniew Darzynkiewicz
Potentiation of tumor necrosis factor induced apoptosis by onconase.
International journal of oncology 1998;13(1):11-6.
1996: Zbigniew Darzynkiewicz; J Gong; Gloria Juan; Barbara Ardelt; Frank Traganos
Cytometry of cyclin proteins.
Cytometry 1996;25(1):1-13.
1995: H Dorota Halicka; Barbara Ardelt; Xuguang Li; M M Melamed; Zbigniew Darzynkiewicz
2-Deoxy-D-glucose enhances sensitivity of human histiocytic lymphoma U937 cells to apoptosis induced by tumor necrosis factor.
Cancer research 1995;55(2):444-9.
1994: J Gong; Barbara Ardelt; Frank Traganos; Zbigniew Darzynkiewicz
Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines.
Cancer research 1994;54(16):4285-8.
1994: Frank Traganos; J Gong; Barbara Ardelt; Zbigniew Darzynkiewicz
Effect of staurosporine on MOLT-4 cell progression through G2 and on cytokinesis.
Journal of cellular physiology 1994;158(3):535-44.
1993: Frank Traganos; J Kapuscinski; J Gong; Barbara Ardelt; R J Darzynkiewicz; Zbigniew Darzynkiewicz
Caffeine prevents apoptosis and cell cycle effects induced by camptothecin or topotecan in HL-60 cells.
Cancer research 1993;53(19):4613-8.
1993: Wojciech Gorczyca; J Gong; Barbara Ardelt; Frank Traganos; Zbigniew Darzynkiewicz
The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents.
Cancer research 1993;53(13):3186-92.
1992: Frank Traganos; Barbara Ardelt; N Halko; S Bruno; Zbigniew Darzynkiewicz
Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells.
Cancer research 1992;52(22):6200-8.
1992: S Bruno; Barbara Ardelt; J S Skierski; Frank Traganos; Zbigniew Darzynkiewicz
Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes.
Cancer research 1992;52(2):470-3.