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Albert Goldbeter

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Claude Gérard; Didier Gonze; Albert Goldbeter
Effect of positive feedback loops on the robustness of oscillations in the network of cyclin-dependent kinases driving the mammalian cell cycle.
Albert Goldbeter; Didier Gonze; Jean-Christophe LELOUP; C Gérard; G Dupont
Systems biology of cellular rhythms.
Claude Gérard; Albert Goldbeter
Entrainment of the mammalian cell cycle by the circadian clock: modeling two coupled cellular rhythms.

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All Publications

2012: Claude Gérard; Didier Gonze; Albert Goldbeter
Effect of positive feedback loops on the robustness of oscillations in the network of cyclin-dependent kinases driving the mammalian cell cycle.
The FEBS journal 2012;279(18):3411-31.
2012: Albert Goldbeter; Didier Gonze; Jean-Christophe LELOUP; C Gérard; G Dupont
Systems biology of cellular rhythms.
FEBS letters 2012;586(18):2955-65.
2012: Claude Gérard; Albert Goldbeter
Entrainment of the mammalian cell cycle by the circadian clock: modeling two coupled cellular rhythms.
PLoS computational biology 2012;8(5):e1002516.
2012: Claude Gérard; Albert Goldbeter
From quiescence to proliferation: Cdk oscillations drive the mammalian cell cycle.
Frontiers in physiology 2012;3():413.
2011: Albert Goldbeter
A model for the dynamics of bipolar disorders.
Progress in biophysics and molecular biology 2011;105(1-2):119-27.
2011: Atilla Altinok; Didier Gonze; Francis Lévi; Albert Goldbeter
An automaton model for the cell cycle.
Interface focus 2011;1(1):36-47.
2011: Claude Gérard; Albert Goldbeter
A skeleton model for the network of cyclin-dependent kinases driving the mammalian cell cycle.
Interface focus 2011;1(1):24-35.
2011: Albert Goldbeter
[Biological oscillations: clocks for all times].
Médecine sciences : M/S 2011;27(2):115-6.
2011: Jean-Christophe LELOUP; Albert Goldbeter
Modelling the dual role of Per phosphorylation and its effect on the period and phase of the mammalian circadian clock.
IET systems biology 2011;5(1):44.
2010: Claude Gérard; Albert Goldbeter
From simple to complex patterns of oscillatory behavior in a model for the mammalian cell cycle containing multiple oscillatory circuits.
Chaos (Woodbury, N.Y.) 2010;20(4):045109.
2010: Albert Goldbeter; Claude Gérard; Jean-Christophe LELOUP
[Circadian rhythms and systems biology].
Médecine sciences : M/S 2010;26(1):49-56.
2009: Claude Gérard; Albert Goldbeter
Temporal self-organization of the cyclin/Cdk network driving the mammalian cell cycle.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(51):21643-8.
2009: Claude Gérard; Didier Gonze; Albert Goldbeter
Dependence of the period on the rate of protein degradation in minimal models for circadian oscillations.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2009;367(1908):4665-83.
2009: Atilla Altinok; Francis Lévi; Albert Goldbeter
Identifying mechanisms of chronotolerance and chronoefficacy for the anticancer drugs 5-fluorouracil and oxaliplatin by computational modeling.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;36(1):20-38.
2008: Francis Lévi; Atilla Altinok; Jean Clairambault; Albert Goldbeter
Implications of circadian clocks for the rhythmic delivery of cancer therapeutics.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2008;366(1880):3575-98.
2008: Albert Goldbeter
Biological rhythms: clocks for all times.
Current biology : CB 2008;18(17):R751-R753.
2008: Didier Gonze; Nicolas Markadieu; Albert Goldbeter
Selection of in-phase or out-of-phase synchronization in a model based on global coupling of cells undergoing metabolic oscillations.
Chaos (Woodbury, N.Y.) 2008;18(3):037127.
2008: John J Tyson; Reka Albert; Albert Goldbeter; Peter Ruoff; Jill Sible
Biological switches and clocks.
Journal of the Royal Society, Interface / the Royal Society 2008;5 Suppl 1():S1-8.
2008: Didier Gonze; Michel Jacquet; Albert Goldbeter
Stochastic modelling of nucleocytoplasmic oscillations of the transcription factor Msn2 in yeast.
Journal of the Royal Society, Interface / the Royal Society 2008;5 Suppl 1():S95-109.
2008: Albert Goldbeter; Olivier Pourquié
Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways.
Journal of theoretical biology 2008;252(3):574-85.
2008: Jean-Christophe LELOUP; Albert Goldbeter
Modeling the circadian clock: from molecular mechanism to physiological disorders.
BioEssays : news and reviews in molecular, cellular and developmental biology 2008;30(6):590-600.
2008: Marina Caldara; Geneviève Dupont; Frédéric Leroy; Albert Goldbeter; Luc De Vuyst; Raymond Cunin
Arginine biosynthesis in Escherichia coli: experimental perturbation and mathematical modeling.
The Journal of biological chemistry 2008;283(10):6347-58.
2007: Atilla Altinok; Francis Lévi; Albert Goldbeter
A cell cycle automaton model for probing circadian patterns of anticancer drug delivery.
Advanced drug delivery reviews 2007;59(9-10):1036-53.
2007: Cecilia Garmendia-Torres; Albert Goldbeter; Michel Jacquet
Nucleocytoplasmic oscillations of the yeast transcription factor Msn2: evidence for periodic PKA activation.
Current biology : CB 2007;17(12):1044-9.
2007: Albert Goldbeter; Didier Gonze; Olivier Pourquié
Sharp developmental thresholds defined through bistability by antagonistic gradients of retinoic acid and FGF signaling.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(6):1495-508.
2006: Gen Kurosawa; Albert Goldbeter
Amplitude of circadian oscillations entrained by 24-h light-dark cycles.
Journal of theoretical biology 2006;242(2):478-88.
2006: Albert Goldbeter
Oscillations and waves of cyclic AMP in Dictyostelium: a prototype for spatio-temporal organization and pulsatile intercellular communication.
Bulletin of mathematical biology 2006;68(5):1095-109.
2006: Didier Gonze; Albert Goldbeter
Circadian rhythms and molecular noise.
Chaos (Woodbury, N.Y.) 2006;16(2):026110.
2006: Albert Goldbeter
A model for the dynamics of human weight cycling.
Journal of biosciences 2006;31(1):129-36.
2005: Ewan Birney; Andrea Ciliberto; Morten Colding-Jørgensen; Albert Goldbeter; Stefan Hohmann; Martin Kuiper; Hans Lehrach; Gisela Miczka; Erik Mosekilde; Hans Westerhoff; Olaf Wolkenhauer
Report of an EU projects workshop on systems biology held in Brussels, Belgium on 8 December 2004.
Systems biology 2005;152(2):55-60.
2005: Albert Goldbeter
Zero-order switches and developmental thresholds.
Molecular systems biology 2005;1():2005.0031.
2004: Oleg A Igoshin; Albert Goldbeter; Armin Dale Kaiser; George Oster
A biochemical oscillator explains several aspects of Myxococcus xanthus behavior during development.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15760-5.
2004: Jean-Christophe LELOUP; Albert Goldbeter
Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms.
Journal of theoretical biology 2004;230(4):541-62.
2004: Albert Goldbeter
Computational biology: a propagating wave of interest.
Current biology : CB 2004;14(15):R601-2.
2003: Olivier Pourquié; Albert Goldbeter
Segmentation clock: insights from computational models.
Current biology : CB 2003;13(16):R632-4.
2003: Michel Jacquet; Georges Renault; Sylvie Lallet; Jan De Mey; Albert Goldbeter
Oscillatory behavior of the nuclear localization of the transcription factors Msn2 and Msn4 in response to stress in yeast.
TheScientificWorldJournal 2003;3():609-12.
2003: Jean-Christophe LELOUP; Albert Goldbeter
Toward a detailed computational model for the mammalian circadian clock.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(12):7051-6.
2003: Didier Gonze; José Halloy; Albert Goldbeter
[Deterministic and stochastic models for circadian rhythms].
Pathologie-biologie 2003;51(4):227-30.
2003: Michel Jacquet; Georges Renault; Sylvie Lallet; Jan De Mey; Albert Goldbeter
Oscillatory nucleocytoplasmic shuttling of the general stress response transcriptional activators Msn2 and Msn4 in Saccharomyces cerevisiae.
The Journal of cell biology 2003;161(3):497-505.
2003: Didier Gonze; José Halloy; Jean-Christophe LELOUP; Albert Goldbeter
Stochastic models for circadian rhythms: effect of molecular noise on periodic and chaotic behaviour.
Comptes rendus biologies 2003;326(2):189-203.
2003: Daniel B Forger; Dennis A Dean; Katherine Gurdziel; Jean-Christophe LELOUP; Choogon Lee; Charlotte von Gall; Jean-Pierre Etchegaray; Richard E Kronauer; Albert Goldbeter; Charles S Peskin; Megan E Jewett; David R Weaver
Development and validation of computational models for mammalian circadian oscillators.
Omics : a journal of integrative biology 2003;7(4):387-400.
2002: Didier Gonze; José Halloy; Albert Goldbeter
Deterministic versus stochastic models for circadian rhythms.
Journal of biological physics 2002;28(4):637-53.
2002: Albert Goldbeter
Computational approaches to cellular rhythms.
Nature 2002;420(6912):238-45.
2002: Didier Gonze; Marc R Roussel; Albert Goldbeter
A model for the enhancement of fitness in cyanobacteria based on resonance of a circadian oscillator with the external light-dark cycle.
Journal of theoretical biology 2002;214(4):577-97.
2002: José Halloy; B A Bernard; G Loussouarn; Albert Goldbeter
The follicular automaton model: effect of stochasticity and of synchronization of hair cycles.
Journal of theoretical biology 2002;214(3):469-79.
2002: Didier Gonze; José Halloy; Albert Goldbeter
Robustness of circadian rhythms with respect to molecular noise.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):673-8.
2001: Didier Gonze; Albert Goldbeter
A model for a network of phosphorylation-dephosphorylation cycles displaying the dynamics of dominoes and clocks.
Journal of theoretical biology 2001;210(2):167-86.
2001: Jean-Christophe LELOUP; Albert Goldbeter
A molecular explanation for the long-term suppression of circadian rhythms by a single light pulse.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(4):R1206-12.
2000: M R Roussel; Didier Gonze; Albert Goldbeter
Modeling the differential fitness of cyanobacterial strains whose circadian oscillators have different free-running periods: comparing the mutual inhibition and substrate depletion hypotheses.
Journal of theoretical biology 2000;205(2):321-40.
2000: José Halloy; B A Bernard; G Loussouarn; Albert Goldbeter
Modeling the dynamics of human hair cycles by a follicular automaton.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8328-33.
2000: GM Guidi; Albert Goldbeter
Oscillations and bistability predicted by a model for a cyclical bienzymatic system involving the regulated isocitrate dehydrogenase reaction.
Biophysical chemistry 2000;83(2):153-70.
2000: Albert Goldbeter; Geneviève Dupont; José Halloy
The frequency encoding of pulsatility.
Novartis Foundation symposium 2000;227():19-36; discussion 36-45.
2000: Didier Gonze; Jean-Christophe LELOUP; Albert Goldbeter
Theoretical models for circadian rhythms in Neurospora and Drosophila.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 2000;323(1):57-67.
2000: Jean-Christophe LELOUP; Albert Goldbeter
Modeling the molecular regulatory mechanism of circadian rhythms in Drosophila.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(1):84-93.
1999: Jean-Christophe LELOUP; Didier Gonze; Albert Goldbeter
Limit cycle models for circadian rhythms based on transcriptional regulation in Drosophila and Neurospora.
Journal of biological rhythms 1999;14(6):433-48.
1999: P C Romond; M Rustici; Didier Gonze; Albert Goldbeter
Alternating oscillations and chaos in a model of two coupled biochemical oscillators driving successive phases of the cell cycle.
Annals of the New York Academy of Sciences 1999;879():180-93.
1999: G Houart; Geneviève Dupont; Albert Goldbeter
Bursting, chaos and birhythmicity originating from self-modulation of the inositol 1,4,5-trisphosphate signal in a model for intracellular Ca2+ oscillations.
Bulletin of mathematical biology 1999;61(3):507-30.
1998: C Pérez-Iratxeta; José Halloy; F Morán; Jean-Louis Martiel; Albert Goldbeter
Coexistence of multiple propagating wave-fronts in a regulated enzyme reaction model: link with birhythmicity and multi-threshold excitability.
Biophysical chemistry 1998;74(3):197-207.
1998: Geneviève Dupont; Albert Goldbeter
CaM kinase II as frequency decoder of Ca2+ oscillations.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(8):607-10.
1998: GM Guidi; Albert Goldbeter
From bistability to oscillations in a model for the isocitrate dehydrogenase reaction.
Biophysical chemistry 1998;72(1-2):201-10.
1998: José Halloy; J Lauzeral; Albert Goldbeter
Modeling oscillations and waves of cAMP in Dictyostelium discoideum cells.
Biophysical chemistry 1998;72(1-2):9-19.
1998: GM Guidi; M F Carlier; Albert Goldbeter
Bistability in the isocitrate dehydrogenase reaction: an experimentally based theoretical study.
Biophysical journal 1998;74(3):1229-40.
1998: Jean-Christophe LELOUP; Albert Goldbeter
A model for circadian rhythms in Drosophila incorporating the formation of a complex between the PER and TIM proteins.
Journal of biological rhythms 1998;13(1):70-87.
1997: Jean-Christophe LELOUP; Albert Goldbeter
Temperature compensation of circadian rhythms: control of the period in a model for circadian oscillations of the per protein in Drosophila.
Chronobiology international 1997;14(5):511-20.
1997: J Lauzeral; José Halloy; Albert Goldbeter
Desynchronization of cells on the developmental path triggers the formation of spiral waves of cAMP during Dictyostelium aggregation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9153-8.
1997: J M Borghans; Geneviève Dupont; Albert Goldbeter
Complex intracellular calcium oscillations. A theoretical exploration of possible mechanisms.
Biophysical chemistry 1997;66(1):25-41.
1996: Geneviève Dupont; J Pontes; Albert Goldbeter
Modeling spiral Ca2+ waves in single cardiac cells: role of the spatial heterogeneity created by the nucleus.
The American journal of physiology 1996;271(4 Pt 1):C1390-9.
1996: Albert Goldbeter; J M Guilmot
Arresting the mitotic oscillator and the control of cell proliferation: insights from a cascade model for cdc2 kinase activation.
Experientia 1996;52(3):212-6.
1996: Albert Goldbeter; J M Guilmot; P C Romond
[Control of cell proliferation: towards new strategies suggested by modelling the mitotic oscillator].
Pathologie-biologie 1996;44(3):172-8.
1995: Albert Goldbeter
A model for circadian oscillations in the Drosophila period protein (PER).
Proceedings. Biological sciences / The Royal Society 1995;261(1362):319-24.
1994: Geneviève Dupont; Albert Goldbeter
Properties of intracellular Ca2+ waves generated by a model based on Ca(2+)-induced Ca2+ release.
Biophysical journal 1994;67(6):2191-204.
1993: Geneviève Dupont; Albert Goldbeter
One-pool model for Ca2+ oscillations involving Ca2+ and inositol 1,4,5-trisphosphate as co-agonists for Ca2+ release.
Cell calcium 1993;14(4):311-22.
1992: Geneviève Dupont; Albert Goldbeter
Oscillations and waves of cytosolic calcium: insights from theoretical models.
BioEssays : news and reviews in molecular, cellular and developmental biology 1992;14(7):485-93.
1992: Y Li; José Halloy; Jean-Louis Martiel; B Wurster; Albert Goldbeter
Suppression of chaos by periodic oscillations in a model for cyclic AMP signalling in Dictyostelium cells.
Experientia 1992;48(6):603-6.
1992: Geneviève Dupont; Albert Goldbeter
Protein phosphorylation driven by intracellular calcium oscillations: a kinetic analysis.
Biophysical chemistry 1992;42(3):257-70.
1992: Y Li; Albert Goldbeter
Pulsatile signaling in intercellular communication. Periodic stimuli are more efficient than random or chaotic signals in a model based on receptor desensitization.
Biophysical journal 1992;61(1):161-71.
1991: Albert Goldbeter
A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9107-11.
1991: Geneviève Dupont; M J Berridge; Albert Goldbeter
Signal-induced Ca2+ oscillations: properties of a model based on Ca(2+)-induced Ca2+ release.
Cell calcium 1991;12(2-3):73-85.
1990: Y Li; Albert Goldbeter
Frequency encoding of pulsatile signals of cAMP based on receptor desensitization in Dictyostelium cells.
Journal of theoretical biology 1990;146(3):355-67.
1990: Geneviève Dupont; M J Berridge; Albert Goldbeter
Latency correlates with period in a model for signal-induced Ca2+ oscillations based on Ca2(+)-induced Ca2+ release.
Cell regulation 1990;1(11):853-61.
1990: Albert Goldbeter; Geneviève Dupont
Allosteric regulation, cooperativity, and biochemical oscillations.
Biophysical chemistry 1990;37(1-3):341-53.
1990: Albert Goldbeter; Geneviève Dupont; M J Berridge
Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1461-5.
1990: Albert Goldbeter; L Wolpert
Covalent modification of proteins as a threshold mechanism in development.
Journal of theoretical biology 1990;142(2):243-50.
1990: Albert Goldbeter; Y Li; Geneviève Dupont
Oscillatory dynamics in intercellular communication.
Biomedica biochimica acta 1990;49(8-9):935-40.
1989: Y Li; Albert Goldbeter
Oscillatory isozymes as the simplest model for coupled biochemical oscillators.
Journal of theoretical biology 1989;138(2):149-74.
1989: Albert Goldbeter; B Wurster
Regular oscillations in suspensions of a putatively chaotic mutant of Dictyostelium discoideum.
Experientia 1989;45(4):363-5.
1989: Y Li; Albert Goldbeter
Frequency specificity in intercellular communication. Influence of patterns of periodic signaling on target cell responsiveness.
Biophysical journal 1989;55(1):125-45.
1988: Albert Goldbeter; O Decroly; Y Li; Jean-Louis Martiel; F Moran
Finding complex oscillatory phenomena in biochemical systems. An empirical approach.
Biophysical chemistry 1988;29(1-2):211-7.
1988: Albert Goldbeter; F Moran
Dynamics of a biochemical system with multiple oscillatory domains as a clue for multiple modes of neuronal oscillations.
European biophysics journal : EBJ 1988;15(5):277-87.
1987: O Decroly; Albert Goldbeter
From simple to complex oscillatory behaviour: analysis of bursting in a multiply regulated biochemical system.
Journal of theoretical biology 1987;124(2):219-50.
1985: F Moran; Albert Goldbeter
Excitability with multiple thresholds. A new mode of dynamic behavior analyzed in a regulated biochemical system.
Biophysical chemistry 1985;23(1-2):71-7.
1985: O Decroly; Albert Goldbeter
Selection between multiple periodic regimes in a biochemical system: complex dynamic behaviour resolved by use of one-dimensional maps.
Journal of theoretical biology 1985;113(4):649-71.
1985: Jean-Louis Martiel; Albert Goldbeter
Autonomous chaotic behaviour of the slime mould Dictyostelium discoideum predicted by a model for cyclic AMP signalling.
Nature 1985;313(6003):590-2.
1984: F Morán; Albert Goldbeter
Onset of birhythmicity in a regulated biochemical system.
Biophysical chemistry 1984;20(1-2):149-56.
1983: Albert Goldbeter; O Decroly
Temporal self-organization in biochemical systems: periodic behavior vs. chaos.
The American journal of physiology 1983;245(4):R478-83.
1982: O Decroly; Albert Goldbeter
Birhythmicity, chaos, and other patterns of temporal self-organization in a multiply regulated biochemical system.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(22):6917-21.
1981: Jean-Louis Martiel; Albert Goldbeter
Metabolic oscillations in biochemical systems controlled by covalent enzyme modification.
Biochimie 1981;63(2):119-24.