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Roy Goldie

Research Profile

Anatomy

Chemicals & Drugs

Phenomena

Muscle Contraction

Living Beings

Procedures

Autoradiography

Disorders

Asthma

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Publications

TOP 3
Lynette B Fernandes; Peter J Henry; Roy G Goldie
Rho kinase as a therapeutic target in the treatment of asthma and chronic obstructive pulmonary disease.
Lynette Fernandes; Angela C d'Aprile; Glenn Self; Melanie McGuire; Tracey Sew; Peter Henry; Roy G Goldie
A Rho-kinase inhibitor, Y-27632, reduces cholinergic contraction but not neurotransmitter release.
Allen C Myers; Roy G Goldie; Douglas W P Hay
A novel role for tachykinin neurokinin-3 receptors in regulation of human bronchial Ganglia neurons.

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All Publications

2007: Lynette B Fernandes; Peter J Henry; Roy G Goldie
Rho kinase as a therapeutic target in the treatment of asthma and chronic obstructive pulmonary disease.
Therapeutic advances in respiratory disease 2007;1(1):25-33.
2006: Lynette Fernandes; Angela C d'Aprile; Glenn Self; Melanie McGuire; Tracey Sew; Peter Henry; Roy G Goldie
A Rho-kinase inhibitor, Y-27632, reduces cholinergic contraction but not neurotransmitter release.
European journal of pharmacology 2006;550(1-3):155-61.
2005: Allen C Myers; Roy G Goldie; Douglas W P Hay
A novel role for tachykinin neurokinin-3 receptors in regulation of human bronchial Ganglia neurons.
American journal of respiratory and critical care medicine 2005;171(3):212-6.
2005: Peter J Henry; Tracy S Mann; Roy G Goldie
A rho kinase inhibitor, Y-27632 inhibits pulmonary eosinophilia, bronchoconstriction and airways hyperresponsiveness in allergic mice.
Pulmonary pharmacology & therapeutics 2005;18(1):67-74.
2004: Lynette B Fernandes; Angela C d'Aprile; Glenn Self; Gerald B Harnett; Roy G Goldie
The impact of respiratory syncytial virus infection on endothelin receptor function and release in sheep bronchial explants.
Journal of cardiovascular pharmacology 2004;44 Suppl 1():S202-6.
2004: Rommel S Lan; Geoffrey A Stewart; Roy G Goldie; Peter J Henry
Altered expression and in vivo lung function of protease-activated receptors during influenza A virus infection in mice.
American journal of physiology. Lung cellular and molecular physiology 2004;286(2):L388-98.
2003: Lynette B Fernandes; Roy G Goldie
The single mediator approach to asthma therapy: is it so unreasonable?
Current opinion in pharmacology 2003;3(3):251-6.
2002: Peter J Henry; Tracy S Mann; Angela C d'Aprile; Glenn Self; Roy G Goldie
An endothelin receptor antagonist, SB-217242, inhibits airway hyperresponsiveness in allergic mice.
American journal of physiology. Lung cellular and molecular physiology 2002;283(5):L1072-8.
2002: Benjamin A De Campo; Roy G Goldie; Arco Y Jeng; Peter J Henry
Role of endothelin-converting enzyme, chymase and neutral endopeptidase in the processing of big ET-1, ET-1(1-21) and ET-1(1-31) in the trachea of allergic mice.
Clinical science (London, England : 1979) 2002;103 Suppl 48():353S-356S.
2002: Roy G Goldie; Angela C d'Aprile; Richard J Betts; Lynette B Fernandes
Enhanced ET(A) receptor-mediated contractile function is associated with reduced ET(A) receptor density in sheep bronchial explants maintained in culture.
Clinical science (London, England : 1979) 2002;103 Suppl 48():349S-352S.
2002: Angela C d'Aprile; Lynette B Fernandes; Paul Rigby; Roy G Goldie
Impact of parainfluenza-3 virus infection on endothelin receptor density and function in guinea pig airways.
Clinical science (London, England : 1979) 2002;103 Suppl 48():345S-348S.
2002: Roy G Goldie; Lynette Fernandes; Paul Rigby
Airway nerves: detection and visualisation.
Current opinion in pharmacology 2002;2(3):273-7.
2001: Douglas W P Hay; Stephen Douglas; Zhaohui Ao; R M Moesker; Glenn Self; Paul Rigby; Mark A Luttmann; Roy G Goldie
Differential modulation of endothelin ligand-induced contraction in isolated tracheae from endothelin B (ET(B)) receptor knockout mice.
British journal of pharmacology 2001;132(8):1905-15.
2001: Roy G Goldie; Paul Rigby; Lynette B Fernandes; Peter J Henry
The impact of inflammation on bronchial neuronal networks.
Pulmonary pharmacology & therapeutics 2001;14(3):177-82.
2000: Roy G Goldie; Angela C d'Aprile; Glenn Self; Paul Rigby; Peter J Henry
Influence of endothelin-1(1-31) on smooth muscle tone and cholinergic nerve-mediated contraction in rat isolated trachea.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S228-31.
2000: Darryl A Knight; Angela C d'Aprile; LJ Spalding; Roy G Goldie; Philip J Thompson
Leukaemia inhibitory factor (LIF) upregulates excitatory non-adrenergic non-cholinergic and maintains cholinergic neural function in tracheal explants.
British journal of pharmacology 2000;130(5):975-9.
2000: Roy G Goldie; Lynette B Fernandes
A possible mediator role for endothelin-1 in respiratory disease.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 2000;55(2):162-7.
2000: JM Preuss; Paul Rigby; Roy G Goldie
Ageing and epithelial integrity as modulators of airway smooth muscle responsiveness to endothelin-1.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(4):391-6.
1999: P J Rigby; Roy G Goldie
Confocal microscopy in biomedical research.
Croatian medical journal 1999;40(3):346-52.
1999: Lynette B Fernandes; Peter J Henry; Roy G Goldie
Endothelin-1 potentiates cholinergic nerve-mediated contraction in human isolated bronchus.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(2):439-42.
1999: JM Preuss; Roy G Goldie
Age-related changes in muscarinic cholinoceptor function in guinea-pig and rat airways.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(2):179-86.
1999: JM Preuss; Paul Rigby; Roy G Goldie
The influence of animal age on beta-adrenoceptor density and function in tracheal airway smooth muscle.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(2):171-8.
1999: Peter J Henry; MJ Carr; Roy G Goldie; Arco Y Jeng
The role of endothelin in mediating virus-induced changes in endothelinB receptor density in mouse airways.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(1):92-7.
1999: JM Preuss; Roy G Goldie
Muscarinic cholinoceptor subtypes mediating tracheal smooth muscle contraction and inositol phosphate generation in guinea pig and rat.
European journal of pharmacology 1999;372(3):269-77.
1999: Douglas W P Hay; Mark A Luttmann; RM Muccitelli; Roy G Goldie
Endothelin receptors and calcium translocation pathways in human airways.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(5):404-10.
1999: Thomas M Cocks; B Fong; JM Chow; G P Anderson; Albert G Frauman; Roy G Goldie; Peter J Henry; MJ Carr; Justin R Hamilton; James D Moffatt
A protective role for protease-activated receptors in the airways.
Nature 1999;398(6723):156-60.
1999: Roy G Goldie
Endothelins in health and disease: an overview.
Clinical and experimental pharmacology & physiology 1999;26(2):145-8.
1999: Lynette B Fernandes; Angela C d'Aprile; Peter J Henry; LJ Spalding; CJ Pudney; Roy G Goldie
Detection of endothelin receptors in rat and guinea-pig airway nerves by immunohistochemistry.
Pulmonary pharmacology & therapeutics 1999;12(5):313-23.
1999: JM Preuss; Roy G Goldie
Age-related changes in airway responsiveness to phosphodiesterase inhibitors and activators of adenyl cyclase and guanylyl cyclase.
Pulmonary pharmacology & therapeutics 1999;12(4):237-43.
1999: Roy G Goldie; Peter J Henry
Endothelins and asthma.
Life sciences 1999;65(1):1-15.
1999: Roy G Goldie
Potential role of the endothelins in airway remodelling in asthma.
Pulmonary pharmacology & therapeutics 1999;12(2):79-80.
1998: M J Maxwell; Roy G Goldie; Peter J Henry
Ca2+ signalling by endothelin receptors in rat and human cultured airway smooth muscle cells.
British journal of pharmacology 1998;125(8):1768-78.
1998: Roy G Goldie; Lynette B Fernandes; P J Rigsby; CJ Pudney; LJ Spalding; B J O'Connor; C P Page
Airway structure: a role for confocal microscopy?
Pulmonary pharmacology & therapeutics 1998;11(5-6):349-54.
1998: Douglas W P Hay; Roy G Goldie
Potential pathophysiological role of endothelin-1 in asthma.
Drug news & perspectives 1998;11(7):411-8.
1998: M J Maxwell; Roy G Goldie; Peter J Henry
Altered ETB- but not ETA-receptor density and function in sheep airway smooth muscle cells in culture.
The American journal of physiology 1998;274(6 Pt 1):L951-7.
1998: Roy G Goldie
Endothelin receptor subtypes: distribution and function in the lung.
Pulmonary pharmacology & therapeutics 1998;11(2-3):89-95.
1998: JM Preuss; Paul Rigby; Roy G Goldie
The influence of post-mortem conditions on contractile and relaxant responsiveness of guinea-pig isolated tracheal smooth muscle.
Naunyn-Schmiedeberg's archives of pharmacology 1998;357(4):454-65.
1998: JM Preuss; Paul Rigby; Roy G Goldie
Age and region-dependent contraction to alpha-adrenoceptor agonists in rat and guinea-pig isolated trachea.
British journal of pharmacology 1998;123(8):1541-8.
1998: JM Preuss; Roy G Goldie
The influence of age on isolated tracheal responsiveness to spasmogens.
European journal of pharmacology 1998;345(1):71-7.
1998: Lynette B Fernandes; Peter J Henry; LJ Spalding; SH Cody; CJ Pudney; Roy G Goldie
Immunocytochemical detection of endothelin receptors in rat cultured airway nerves.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S222-4.
1998: Roy G Goldie; Peter J Henry; Paul Rigby; P G Knott
Influence of respiratory tract viral infection on endothelin-1-induced modulation of cholinergic nerve-mediated contractions in murine airway smooth muscle.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S219-21.
1998: MJ Carr; LJ Spalding; Roy G Goldie; Peter J Henry
Distribution of immunoreactive endothelin in the lungs of mice during respiratory viral infection.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(1):79-85.
1997: Roy G Goldie; Paul Rigby; CJ Pudney; SH Cody
Confocal microscopy and the respiratory tract.
Pulmonary pharmacology & therapeutics 1997;10(4):175-88.
1996: Douglas W P Hay; P J Henry; Roy G Goldie
Is endothelin-1 a mediator in asthma?
American journal of respiratory and critical care medicine 1996;154(6 Pt 1):1594-7.
1996: P G Knott; Lynette B Fernandes; Peter J Henry; Roy G Goldie
Influence of endothelin-1 on cholinergic nerve-mediated contractions and acetylcholine release in rat isolated tracheal smooth muscle.
The Journal of pharmacology and experimental therapeutics 1996;279(3):1142-7.
1996: M J Carr; Roy G Goldie; Peter J Henry
Influence of respiratory tract viral infection on endothelin-1-induced potentiation of cholinergic nerve-mediated contraction in mouse trachea.
British journal of pharmacology 1996;119(5):891-8.
1996: P G Knott; Peter J Henry; A S McWilliam; Paul Rigby; Lynette B Fernandes; Roy G Goldie
Influence of parainfluenza-1 respiratory tract viral infection on endothelin receptor-effector systems in mouse and rat tracheal smooth muscle.
British journal of pharmacology 1996;119(2):291-8.
1996: Lynette B Fernandes; Peter J Henry; Paul Rigby; Roy G Goldie
EndothelinB (ETB) receptor-activated potentiation of cholinergic nerve-mediated contraction in human bronchus.
British journal of pharmacology 1996;118(8):1873-4.
1996: Peter J Henry; A Shen; Frederick Mitchelson; Roy G Goldie
Inhibition by endothelin-1 of cholinergic nerve-mediated acetylcholine release and contraction in sheep isolated trachea.
British journal of pharmacology 1996;118(3):762-8.
1996: Roy G Goldie; P G Knott; M J Carr; Douglas W P Hay; Peter J Henry
The endothelins in the pulmonary system.
Pulmonary pharmacology 1996;9(2):69-93.
1996: M J Carr; Roy G Goldie; Peter J Henry
Time course of changes in ETB receptor density and function in tracheal airway smooth muscle during respiratory tract viral infection in mice.
British journal of pharmacology 1996;117(6):1222-8.
1996: G M Renshaw; Roy G Goldie
Neuronal bungarotoxin displaces (125I) alpha-bungarotoxin binding at the neuromuscular junction as well as to the spinal cord during embryogenesis.
Brain research 1996;709(2):316-8.
1996: Roy G Goldie; A C D'Aprile; R Cvetkovski; Paul Rigby; Peter J Henry
Influence of regional differences in ETA and ETB receptor subtype proportions on endothelin-1-induced contractions in porcine isolated trachea and bronchus.
British journal of pharmacology 1996;117(4):736-42.
1996: Roy G Goldie; A C D'Aprile; G J Self; Paul Rigby; Peter J Henry
The distribution and density of receptor subtypes for endothelin-1 in peripheral lung of the rat, guinea-pig and pig.
British journal of pharmacology 1996;117(4):729-35.
1995: Roy G Goldie; Peter J Henry; P G Knott; G J Self; Mark A Luttmann; Douglas W P Hay
Endothelin-1 receptor density, distribution, and function in human isolated asthmatic airways.
American journal of respiratory and critical care medicine 1995;152(5 Pt 1):1653-8.
1995: Roy G Goldie; K E Pedersen
Mechanisms of increased airway microvascular permeability: role in airway inflammation and obstruction.
Clinical and experimental pharmacology & physiology 1995;22(6-7):387-96.
1995: K M Lulich; J W Paterson; Roy G Goldie
Ipratropium, sodium cromoglycate and antihistamines.
The Medical journal of Australia 1995;162(3):157-9.
1995: Peter J Henry; Roy G Goldie
Potentiation by endothelin-1 of cholinergic nerve-mediated contractions in mouse trachea via activation of ETB receptors.
British journal of pharmacology 1995;114(3):563-9.
1995: Roy G Goldie; K M Lulich; J W Paterson
Bronchodilators: beta-agonists.
The Medical journal of Australia 1995;162(2):100-2.
1995: J W Paterson; K M Lulich; Roy G Goldie
Pharmacology of asthma treatment: an overview.
The Medical journal of Australia 1995;162(1):42-3.
1995: Peter J Henry; Roy G Goldie
Endothelin-1, via activation of an ETB receptor, inhibits cholinergic nerve-mediated contractions in sheep trachea.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S117-9.
1995: P G Knott; A C D'Aprile; Peter J Henry; Douglas W P Hay; Roy G Goldie
Receptors for endothelin-1 in asthmatic human peripheral lung.
British journal of pharmacology 1995;114(1):1-3.
1994: Peter J Henry; Roy G Goldie
ETB but not ETA receptor-mediated contractions to endothelin-1 attenuated by respiratory tract viral infection in mouse airways.
British journal of pharmacology 1994;112(4):1188-94.
1994: Domenico Spina; Roy G Goldie
Poly-L-arginine-mediated release of acetylcholine from parasympathetic nerves in rat and guinea-pig airways.
British journal of pharmacology 1994;112(3):895-900.
1994: Roy G Goldie; P S Grayson; P G Knott; G J Self; Peter J Henry
Predominance of endothelinA (ETA) receptors in ovine airway smooth muscle and their mediation of ET-1-induced contraction.
British journal of pharmacology 1994;112(3):749-56.
1994: Domenico Spina; E Minshall; Roy G Goldie; Clive P Page
The effect of allosteric antagonists in modulating muscarinic M2-receptor function in guinea-pig isolated trachea.
British journal of pharmacology 1994;112(3):901-5.
1994: Domenico Spina; Roy G Goldie
Contractile properties of synthetic cationic polypeptides in guinea-pig isolated trachea.
British journal of pharmacology 1994;111(1):29-34.
1993: G Renshaw; P Rigby; G Self; A Lamb; Roy G Goldie
Exogenously administered alpha-bungarotoxin binds to embryonic chick spinal cord: implications for the toxin-induced arrest of naturally occurring motoneuron death.
Neuroscience 1993;53(4):1163-72.
1992: Paul Rigby; G J Self; Roy G Goldie
Eosinophil peroxidase and 125I- ion binding in guinea-pig trachea.
European journal of pharmacology 1992;228(2-3):141-5.
1992: JM Preuss; Peter J Henry; Roy G Goldie
Influence of age on epithelium-dependent responsiveness of guinea-pig and rat tracheal smooth muscle to spasmogens.
European journal of pharmacology 1992;228(1):3-8.
1992: Domenico Spina; Lynette B Fernandes; JM Preuss; Douglas W P Hay; R M Muccitelli; Clive P Page; Roy G Goldie
Evidence that epithelium-dependent relaxation of vascular smooth muscle detected by co-axial bioassays is not attributable to hypoxia.
British journal of pharmacology 1992;105(4):799-804.
1992: Lynette B Fernandes; JM Preuss; Roy G Goldie
Epithelial modulation of the relaxant activity of atriopeptides in rat and guinea-pig tracheal smooth muscle.
European journal of pharmacology 1992;212(2-3):187-94.
1992: Peter J Henry; Paul Rigby; G J Self; JM Preuss; Roy G Goldie
Endothelin-1-induced [3H]-inositol phosphate accumulation in rat trachea.
British journal of pharmacology 1992;105(1):135-41.
1991: Peter J Henry; Paul Rigby; John S Mackenzie; Roy G Goldie
Effect of respiratory tract viral infection on murine airway beta-adrenoceptor function, distribution and density.
British journal of pharmacology 1991;104(4):914-21.
1991: K E Pedersen; Paul Rigby; Roy G Goldie
Quantitative assessment of increased airway microvascular permeability to 125I-labelled plasma fibrinogen induced by platelet activating factor and bradykinin.
British journal of pharmacology 1991;104(1):128-32.
1991: Lynette B Fernandes; Roy G Goldie
Antigen-induced release of airway epithelium-derived inhibitory factor.
The American review of respiratory disease 1991;143(3):567-71.
1990: Lynette B Fernandes; JM Preuss; J W Paterson; Roy G Goldie
Epithelium-derived inhibitory factor in human bronchus.
European journal of pharmacology 1990;187(3):331-6.
1990: Peter J Henry; Paul Rigby; G J Self; JM Preuss; Roy G Goldie
Relationship between endothelin-1 binding site densities and constrictor activities in human and animal airway smooth muscle.
British journal of pharmacology 1990;100(4):786-92.
1990: Lynette B Fernandes; Roy G Goldie
Pharmacological evaluation of a guinea-pig tracheal epithelium-derived inhibitory factor (EpDIF).
British journal of pharmacology 1990;100(3):614-8.
1990: Roy G Goldie
Receptors in asthmatic airways.
The American review of respiratory disease 1990;141(3 Pt 2):S151-6.
1990: G J Self; Paul Rigby; M C Passarelli; Roy G Goldie
Characteristics and localisation of 125I ion binding in mammalian airways.
European journal of pharmacology 1990;176(2):169-76.
1990: Roy G Goldie; Lynette B Fernandes; Stephen Farmer; Douglas W P Hay
Airway epithelium-derived inhibitory factor.
Trends in pharmacological sciences 1990;11(2):67-70.
1990: Peter J Henry; Roy G Goldie
Beta 1-adrenoceptors mediate smooth muscle relaxation in mouse isolated trachea.
British journal of pharmacology 1990;99(1):131-5.
1990: Roy G Goldie; J W Paterson; K M Lulich
Adrenoceptors in airway smooth muscle.
Pharmacology & therapeutics 1990;48(3):295-322.
1990: Peter J Henry; Paul Rigby; Roy G Goldie
Distribution of beta 1- and beta 2-adrenoceptors in mouse trachea and lung: a quantitative autoradiographic study.
British journal of pharmacology 1990;99(1):136-44.
1990: Roy G Goldie; K E Pedersen; Paul Rigby; J W Paterson
PAF receptors in guinea-pig and human lung.
Agents and actions. Supplements 1990;31():243-6.
1990: Roy G Goldie; Peter J Henry; J W Paterson; JM Preuss; Paul Rigby
Contractile effects and receptor distributions for endothelin-1 (ET-1) in human and animal airways.
Agents and actions. Supplements 1990;31():229-32.
1989: Domenico Spina; Paul Rigby; J W Paterson; Roy G Goldie
Autoradiographic localization of beta-adrenoceptors in asthmatic human lung.
The American review of respiratory disease 1989;140(5):1410-5.
1989: Domenico Spina; Paul Rigby; J W Paterson; Roy G Goldie
Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung.
British journal of pharmacology 1989;97(3):701-8.
1989: Lynette B Fernandes; J W Paterson; Roy G Goldie
Co-axial bioassay of a smooth muscle relaxant factor released from guinea-pig tracheal epithelium.
British journal of pharmacology 1989;96(1):117-24.
1988: Lynette B Fernandes; D A Knight; Paul Rigby; Domenico Spina; J W Paterson; Roy G Goldie
Beta-adrenoceptor desensitization in guinea-pig isolated trachea.
European journal of pharmacology 1988;157(2-3):135-45.
1988: Paul Rigby; M C Passarelli; G J Self; JM Preuss; Roy G Goldie
Ascorbic acid-induced binding of [125I]-iodocyanopindolol to non-beta-adrenoceptor sites in guinea-pig trachea.
Biochemical pharmacology 1988;37(7):1421-4.
1988: J W Paterson; K M Lulich; Roy G Goldie
An overview of the current status of the drug therapy of asthma.
Agents and actions. Supplements 1988;23():15-33.
1988: K M Lulich; Roy G Goldie; J W Paterson
Beta-adrenoceptor function in asthmatic bronchial smooth muscle.
General pharmacology 1988;19(3):307-11.
1988: Roy G Goldie; Lynette B Fernandes; Paul Rigby; J W Paterson
Epithelial dysfunction and airway hyperreactivity in asthma.
Progress in clinical and biological research 1988;263():317-29.
1986: Roy G Goldie; D Spina; Peter J Henry; K M Lulich; J W Paterson
In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline.
British journal of clinical pharmacology 1986;22(6):669-76.
1986: Roy G Goldie; J M Papadimitriou; J W Paterson; Paul Rigby; Domenico Spina
Autoradiographic localization of beta-adrenoceptors in pig lung using [125I]-iodocyanopindolol.
British journal of pharmacology 1986;88(3):621-8.
1986: Roy G Goldie; Domenico Spina; Paul Rigby; J W Paterson
Autoradiographic localisation of ascorbic acid-dependent binding sites for [125I]iodocyanopindolol in guinea-pig trachea.
European journal of pharmacology 1986;124(1-2):179-82.
1986: Roy G Goldie; J M Papadimitriou; J W Paterson; Paul Rigby; H M Self; Domenico Spina
Influence of the epithelium on responsiveness of guinea-pig isolated trachea to contractile and relaxant agonists.
British journal of pharmacology 1986;87(1):5-14.