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Barry Goldstein

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Yajing Wang; Erhe Gao; Ling Tao; Wayne Bond Lau; Yuexin Yuan; Barry J Goldstein; Bernard L Lopez; Theodore A Christopher; Rong Tian; Walter J Koch; Xin-Liang Ma
AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin.
S A Jabbour; Barry J Goldstein
Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes.
Vincent Savarese; Intekhab Ahmed; Barry J Goldstein
Coronary artery disease screening in patients with diabetes.

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2009: Yajing Wang; Erhe Gao; Ling Tao; Wayne Bond Lau; Yuexin Yuan; Barry J Goldstein; Bernard L Lopez; Theodore A Christopher; Rong Tian; Walter J Koch; Xin-Liang Ma
AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin.
Circulation 2009;119(6):835-44.
2008: S A Jabbour; Barry J Goldstein
Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes.
International journal of clinical practice 2008;62(8):1279-84.
2008: Vincent Savarese; Intekhab Ahmed; Barry J Goldstein
Coronary artery disease screening in patients with diabetes.
Endocrine 2008;33(3):225-9.
2008: Yoshimasa Nakamura; Nikolay Patrushev; Hyoe Inomata; Dolly Mehta; Norifumi Urao; Ha Won Kim; Masooma Razvi; Vidisha Kini; Kalyankar Mahadev; Barry J Goldstein; Ronald McKinney; Tohru Fukai; Masuko Fukai
Role of protein tyrosine phosphatase 1B in vascular endothelial growth factor signaling and cell-cell adhesions in endothelial cells.
Circulation research 2008;102(10):1182-91.
2008: Barry J Goldstein
Inflammatory signaling: another drug target to improve glycemic control in type 2 diabetes.
Clinical and translational science 2008;1(1):43-4.
2008: Kumar Sharma; Satish Ramachandrarao; Gang Qiu; Hitomi Kataoka Usui; Yanqing Zhu; Stephen R Dunn; Raogo Ouedraogo; Kelly Hough; Peter McCue; Lawrence Chan; Bonita Falkner; Barry J Goldstein
Adiponectin regulates albuminuria and podocyte function in mice.
The Journal of clinical investigation 2008;118(5):1645-56.
2008: Shi-qiong Xu; Kalyankar Mahadev; Xiangdong Wu; Lauren Fuchsel; Sylvia Donnelly; Rosario G Scalia; Barry J Goldstein
Adiponectin protects against angiotensin II or tumor necrosis factor alpha-induced endothelial cell monolayer hyperpermeability: role of cAMP/PKA signaling.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):899-905.
2008: Kalyankar Mahadev; Xiangdong Wu; Sylvia Donnelly; Raogo Ouedraogo; Andrea D Eckhart; Barry J Goldstein
Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells.
Cardiovascular research 2008;78(2):376-84.
2007: Xiangdong Wu; Kalyankar Mahadev; Lauren Fuchsel; Raogo Ouedraogo; Shi-qiong Xu; Barry J Goldstein
Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling.
American journal of physiology. Endocrinology and metabolism 2007;293(6):E1836-44.
2007: Srinivasa Datla; Hitesh Peshavariya; Gregory J Dusting; Kalyankar Mahadev; Barry J Goldstein; Fan Jiang
Important role of Nox4 type NADPH oxidase in angiogenic responses in human microvascular endothelial cells in vitro.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(11):2319-24.
2007: Steven Rosenzweig; Diane K Reibel; Jeffrey Greeson; Joel S Edman; Samar A Jasser; Kathy D McMearty; Barry J Goldstein
Mindfulness-based stress reduction is associated with improved glycemic control in type 2 diabetes mellitus: a pilot study.
Alternative therapies in health and medicine 2007;13(5):36-8.
2007: Barry J Goldstein; Mark N Feinglos; Jared K Lunceford; Jeremy Johnson; Debora E Williams-Herman
Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes.
Diabetes care 2007;30(8):1979-87.
2007: Barry J Goldstein; Rosario Scalia; Xin L Ma; Kalyankar Mahadev; Xiangdong Wu; Raogo Ouedraogo
Comment on: Hattori et al. (2007) Globular adiponectin activates nuclear factor-kappaB and activating protein-1 and enhances angiotensin II-induced proliferation in cardiac fibroblasts: Diabetes 56:804-808.
Diabetes 2007;56(7):e7-8; author reply e9-10.
2007: Raogo Ouedraogo; Yulan Gong; Brett Berzins; Xiandong Wu; Kalyankar Mahadev; Kelly Hough; Lawrence Chan; Barry J Goldstein; Rosario Scalia
Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo.
The Journal of clinical investigation 2007;117(6):1718-26.
2007: Barry J Goldstein
Clinical translation of "a diabetes outcome progression trial": ADOPT appropriate combination oral therapies in type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2007;92(4):1226-8.
2007: Ling Tao; Erhe Gao; Xiangying Jiao; Yuexing Yuan; Shuzhuang Li; Theodore A Christopher; Bernard L Lopez; Walter J Koch; Lawrence Chan; Barry J Goldstein; Xin L Ma
Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress.
Circulation 2007;115(11):1408-16.
2007: Barry J Goldstein; Rosario Scalia
Adipokines and vascular disease in diabetes.
Current diabetes reports 2007;7(1):25-33.
2007: Intekhab Ahmed; Kevin Furlong; Jeremy Flood; Vanita P Treat; Barry J Goldstein
Dual PPAR alpha/gamma agonists: promises and pitfalls in type 2 diabetes.
American journal of therapeutics 2007;14(1):49-62.
2006: Barry J Goldstein; Julio Rosenstock; Deborah Anzalone; Conrad Tou; K Peter Ohman
Effect of tesaglitazar, a dual PPAR alpha/gamma agonist, on glucose and lipid abnormalities in patients with type 2 diabetes: a 12-week dose-ranging trial.
Current medical research and opinion 2006;22(12):2575-90.
2006: Intekhab Ahmed; Barry J Goldstein
Cardiovascular risk in the spectrum of type 2 diabetes mellitus.
The Mount Sinai journal of medicine, New York 2006;73(5):759-68.
2006: Barry J Goldstein; Peter N Weissman; Margaret J Wooddell; Brian R Waterhouse; Alexander R Cobitz
Reductions in biomarkers of cardiovascular risk in type 2 diabetes with rosiglitazone added to metformin compared with dose escalation of metformin: an EMPIRE trial sub-study.
Current medical research and opinion 2006;22(9):1715-23.
2006: Raogo Ouedraogo; Xiangdong Wu; Shi-qiong Xu; Lauren Fuchsel; Hiroyuki Motoshima; Kalyankar Mahadev; Kelly Hough; Rosario Scalia; Barry J Goldstein
Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway.
Diabetes 2006;55(6):1840-6.
2005: Barry J Goldstein
Intensive insulin therapy regimens: is there a difference in patient satisfaction?
Nature clinical practice. Endocrinology & metabolism 2005;1(2):80-1.
2005: P Weissman; Barry J Goldstein; J Rosenstock; Brian R Waterhouse; Alexander R Cobitz; M J Wooddell; L J Strow
Effects of rosiglitazone added to submaximal doses of metformin compared with dose escalation of metformin in type 2 diabetes: the EMPIRE Study.
Current medical research and opinion 2005;21(12):2029-35.
2005: Daniel E Rosenberg; Serge Jabbour; Barry J Goldstein
Insulin resistance, diabetes and cardiovascular risk: approaches to treatment.
Diabetes, obesity & metabolism 2005;7(6):642-53.
2005: Taishan Hu; Satish P RamachandraRao; Senthuran Siva; Cathryn Valancius; Yanqing Zhu; Kalyankar Mahadev; Irene Toh; Barry J Goldstein; Marilyn Woolkalis; Kumar Sharma
Reactive oxygen species production via NADPH oxidase mediates TGF-beta-induced cytoskeletal alterations in endothelial cells.
American journal of physiology. Renal physiology 2005;289(4):F816-25.
2005: Barry J Goldstein; Kalyankar Mahadev; Xiangdong Wu; Li Zhu; Hiroyuki Motoshima
Role of insulin-induced reactive oxygen species in the insulin signaling pathway.
Antioxidants & redox signaling 2005;7(7-8):1021-31.
2005: Xiangdong Wu; Li Zhu; Assaf Zilbering; Kalyankar Mahadev; Hiroyuki Motoshima; Junli Yao; Barry J Goldstein
Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases.
Antioxidants & redox signaling 2005;7(5-6):526-37.
2005: Barry J Goldstein; Kalyankar Mahadev; Mahadev Kalyankar; Xiangdong Wu
Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets.
Diabetes 2005;54(2):311-21.
2004: Barry J Goldstein; Rosario Scalia
Adiponectin: A novel adipokine linking adipocytes and vascular function.
The Journal of clinical endocrinology and metabolism 2004;89(6):2563-8.
2004: Hiroyuki Motoshima; Xiangdong Wu; Kalyankar Mahadev; Barry J Goldstein
Adiponectin suppresses proliferation and superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL.
Biochemical and biophysical research communications 2004;315(2):264-71.
2004: Kalyankar Mahadev; Hiroyuki Motoshima; Xiangdong Wu; Jean Marie Ruddy; Rebecca S Arnold; Guangjie Cheng; David J. Lambeth; Barry J Goldstein
The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction.
Molecular and cellular biology 2004;24(5):1844-54.
2004: Kalyankar Mahadev; Xiangdong Wu; Hiroyuki Motoshima; Barry J Goldstein
Integration of multiple downstream signals determines the net effect of insulin on MAP kinase vs. PI 3'-kinase activation: potential role of insulin-stimulated H(2)O(2).
Cellular signalling 2004;16(3):323-31.
2003: Tomasz Mazurek; LiFeng Zhang; Andrew Zalewski; John D Mannion; James T Diehl; Hwyda A Arafat; Lea Sarov-Blat; Shawn O'Brien; Elizabeth A Keiper; Anthony G Johnson; Jack Martin; Barry J Goldstein; Yi Shi
Human epicardial adipose tissue is a source of inflammatory mediators.
Circulation 2003;108(20):2460-6.
2003: Xiangdong Wu; V Elise Hardy; Jeffrey I Joseph; Serge Jabbour; Kalyankar Mahadev; Li Zhu; Barry J Goldstein
Protein-tyrosine phosphatase activity in human adipocytes is strongly correlated with insulin-stimulated glucose uptake and is a target of insulin-induced oxidative inhibition.
Metabolism: clinical and experimental 2003;52(6):705-12.
2003: Xiangdong Wu; Hiroyuki Motoshima; Kalyankar Mahadev; Timothy J Stalker; Rosario Scalia; Barry J Goldstein
Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes.
Diabetes 2003;52(6):1355-63.
2003: Barry J Goldstein; Miranda Pans; Cindy J Rubin
Multicenter, randomized, double-masked, parallel-group assessment of simultaneous glipizide/metformin as second-line pharmacologic treatment for patients with type 2 diabetes mellitus that is inadequately controlled by a sulfonylurea.
Clinical therapeutics 2003;25(3):890-903.
2003: Barry J Goldstein
Insulin resistance: from benign to type 2 diabetes mellitus.
Reviews in cardiovascular medicine 2003;4 Suppl 6():S3-10.
2003: Barry J Goldstein; Alexander R Cobitz; Linda M Hand; Hongzi Chen
Are the metabolic effects of rosiglitazone influenced by baseline glycaemic control?
Current medical research and opinion 2003;19(3):192-9.
2002: Hiroyuki Motoshima; Xiangdong Wu; Madhur K Sinha; V Elise Hardy; Ernest L Rosato; Donna J Barbot; Francis E Rosato; Barry J Goldstein
Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone.
The Journal of clinical endocrinology and metabolism 2002;87(12):5662-7.
2002: Barry J Goldstein
Protein-tyrosine phosphatases: emerging targets for therapeutic intervention in type 2 diabetes and related states of insulin resistance.
The Journal of clinical endocrinology and metabolism 2002;87(6):2474-80.
2002: Barry J Goldstein
Differentiating members of the thiazolidinedione class: a focus on efficacy.
Diabetes/metabolism research and reviews 2002;18 Suppl 2():S16-22.
2001: Kalyankar Mahadev; Xiangdong Wu; Assaf Zilbering; Li Zhu; J T Lawrence; Barry J Goldstein
Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes.
The Journal of biological chemistry 2001;276(52):48662-9.
2001: Xiangdong Wu; J Hoffstedt; W Deeb; R Singh; N Sedkova; Assaf Zilbering; Li Zhu; Pauline K Park; P Arner; Barry J Goldstein
Depot-specific variation in protein-tyrosine phosphatase activities in human omental and subcutaneous adipose tissue: a potential contribution to differential insulin sensitivity.
The Journal of clinical endocrinology and metabolism 2001;86(12):5973-80.
2001: Li Zhu; Assaf Zilbering; Xiangdong Wu; Kalyankar Mahadev; Jeffrey I Joseph; Serge Jabbour; W Deeb; Barry J Goldstein
Use of an anaerobic environment to preserve the endogenous activity of protein-tyrosine phosphatases isolated from intact cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1637-9.
2001: Kalyankar Mahadev; Assaf Zilbering; Li Zhu; Barry J Goldstein
Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.
The Journal of biological chemistry 2001;276(24):21938-42.
2000: Barry J Goldstein; A Bittner-Kowalczyk; M F White; M Harbeck
Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.
The Journal of biological chemistry 2000;275(6):4283-9.
1999: JP Ohannesian; C C Marco; P S Najm; Barry J Goldstein; JF Caro; JW Kolaczynski
Small weight gain is not associated with development of insulin resistance in healthy, physically active individuals.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1999;31(5):323-5.
1997: JW Kolaczynski; Barry J Goldstein; RV Considine
Dexamethasone, OB gene, and leptin in humans; effect of exogenous hyperinsulinemia.
The Journal of clinical endocrinology and metabolism 1997;82(11):3895-7.
1997: F Ahmad; RV Considine; TL Bauer; JP Ohannesian; C C Marco; Barry J Goldstein
Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue.
Metabolism: clinical and experimental 1997;46(10):1140-5.
1997: F Ahmad; JL Azevedo; Ronald L Cortright; G Lynis Dohm; Barry J Goldstein
Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes.
The Journal of clinical investigation 1997;100(2):449-58.
1997: F Ahmad; Barry J Goldstein
Functional association between the insulin receptor and the transmembrane protein-tyrosine phosphatase LAR in intact cells.
The Journal of biological chemistry 1997;272(1):448-57.
1997: F Ahmad; Barry J Goldstein
Effect of tumor necrosis factor-alpha on the phosphorylation of tyrosine kinase receptors is associated with dynamic alterations in specific protein-tyrosine phosphatases.
Journal of cellular biochemistry 1997;64(1):117-27.
1996: PM Li; W R Zhang; Barry J Goldstein
Suppression of insulin receptor activation by overexpression of the protein-tyrosine phosphatase LAR in hepatoma cells.
Cellular signalling 1996;8(7):467-73.
1996: PM Li; Barry J Goldstein
Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells.
Biochemical and biophysical research communications 1996;223(1):80-4.
1996: W R Zhang; PM Li; M A Oswald; Barry J Goldstein
Modulation of insulin signal transduction by eutopic overexpression of the receptor-type protein-tyrosine phosphatase LAR.
Molecular endocrinology (Baltimore, Md.) 1996;10(5):575-84.
1996: PM Li; Barry J Goldstein
Cell density-dependent changes in the insulin action pathway: evidence for involvement of protein-tyrosine phosphatases.
Journal of cellular biochemistry 1996;61(1):31-8.
1995: F Ahmad; Barry J Goldstein
Increased abundance of specific skeletal muscle protein-tyrosine phosphatases in a genetic model of insulin-resistant obesity and diabetes mellitus.
Metabolism: clinical and experimental 1995;44(9):1175-84.
1995: F Ahmad; PM Li; J Meyerovitch; Barry J Goldstein
Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway.
The Journal of biological chemistry 1995;270(35):20503-8.
1995: F Ahmad; RV Considine; Barry J Goldstein
Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects.
The Journal of clinical investigation 1995;95(6):2806-12.
1995: F Ahmad; Barry J Goldstein
Purification, identification and subcellular distribution of three predominant protein-tyrosine phosphatase enzymes in skeletal muscle tissue.
Biochimica et biophysica acta 1995;1248(1):57-69.
1994: W R Zhang; N Hashimoto; F Ahmad; W Ding; Barry J Goldstein
Molecular cloning and expression of a unique receptor-like protein-tyrosine-phosphatase in the leucocyte-common-antigen-related phosphate family.
The Biochemical journal 1994;302 ( Pt 1)():39-47.
1994: W Ding; W R Zhang; K Sullivan; N Hashimoto; Barry J Goldstein
Identification of protein-tyrosine phosphatases prevalent in adipocytes by molecular cloning.
Biochemical and biophysical research communications 1994;202(2):902-7.
1993: Barry J Goldstein
Regulation of insulin receptor signaling by protein-tyrosine dephosphorylation.
Receptor 1993;3(1):1-15.