FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Todd Golub

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Disorders

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Co-author Network

Publications

TOP 3
Ahmad Jalili; Mathieu Lupien; Kirsten D Mertz; Mikhail Pashenkov; Gaurav Pathria; Sridhar Ramaswamy; Georg Stingl; Christine Wagner; Jean-Philippe Brunet; David E Fisher; Todd R Golub; Hans R Widlund; Stephan N Wagner
Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma.
Stefano Monti; Donna Neuberg; Scott J Rodig; Kunihiko Takeyama; Kelly T Yeda; Rameen Beroukhim; Bjoern Chapuy; Treeve Currie; Ahmet Dogan; Gad Getz; Todd R Golub; Thomas M Habermann; Yansheng Hao; Haig Inguilizian; Andrew L Kung; Jeffery L Kutok; Craig Mermel; Margaret A Shipp
Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma.
Ravid Straussman; Jennifer A Wargo; Michal Barzily-Rokni; Paul B Chapman; Zachary A Cooper; Ashli Davis; Jinyan Du; Keith T Flaherty; Dennie T Frederick; Joshua Gould; Roger S Lo; Margaret M Mongare; Teppei Morikawa; Shuji Ogino; Zhi Rong Qian; Antoni Ribas; Kevin Shee; David B Solit; Todd R Golub
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Todd Golub (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Ahmad Jalili; Mathieu Lupien; Kirsten D Mertz; Mikhail Pashenkov; Gaurav Pathria; Sridhar Ramaswamy; Georg Stingl; Christine Wagner; Jean-Philippe Brunet; David E Fisher; Todd R Golub; Hans R Widlund; Stephan N Wagner
Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma.
Journal of the National Cancer Institute 2012;104(21):1673-9.
2012: Stefano Monti; Donna Neuberg; Scott J Rodig; Kunihiko Takeyama; Kelly T Yeda; Rameen Beroukhim; Bjoern Chapuy; Treeve Currie; Ahmet Dogan; Gad Getz; Todd R Golub; Thomas M Habermann; Yansheng Hao; Haig Inguilizian; Andrew L Kung; Jeffery L Kutok; Craig Mermel; Margaret A Shipp
Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma.
Cancer cell 2012;22(3):359-72.
2012: Ravid Straussman; Jennifer A Wargo; Michal Barzily-Rokni; Paul B Chapman; Zachary A Cooper; Ashli Davis; Jinyan Du; Keith T Flaherty; Dennie T Frederick; Joshua Gould; Roger S Lo; Margaret M Mongare; Teppei Morikawa; Shuji Ogino; Zhi Rong Qian; Antoni Ribas; Kevin Shee; David B Solit; Todd R Golub
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.
Nature 2012;487(7408):500-4.
2012: Tuoping Luo; Kristina Masson; Nathan T Ross; Christina A Scherer; Claudia Scholl; Stuart L Schreiber; Whitney Silkworth; Andrew M Stern; Steven A Carr; Stefan Fröhling; Jacob D Jaffe; Todd R Golub
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(8):2860-5.
2011: Alice A Chen; Todd R Golub; Luvena L Ong; Robert E Schwartz; David K Thomas; Sangeeta N Bhatia
Humanized mice with ectopic artificial liver tissues.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(29):11842-7.
2011: Michael Green; Stefano Monti; Riccardo Dalla-Favera; Laura Pasqualucci; Nicole C Walsh; Marc Schmidt-Supprian; Jeffery L Kutok; Scott Rodig; Donna S Neuberg; Klaus Rajewsky; Todd R Golub; Frederick W Alt; Margaret A Shipp; John P Manis
Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(7):2873-8.
2011: Noa Novershtern; Aravind Subramanian; Lee N Lawton; Raymond H Mak; W Nicholas Haining; Marie E McConkey; Naomi Habib; Nir Yosef; Cindy Y Chang; Tal Shay; Garrett M Frampton; Adam C B Drake; Ilya Leskov; Bjorn Nilsson; Fred Preffer; David Dombkowski; John W Evans; Ted Liefeld; John S Smutko; Jianzhu Chen; Nir Friedman; Richard A Young; Todd R Golub; Aviv Regev; Benjamin L Ebert
Densely interconnected transcriptional circuits control cell states in human hematopoiesis.
Cell 2011;144(2):296-309.
2010: Michael Green; Stefano Monti; Scott J Rodig; Przemyslaw Juszczynski; Treeve Currie; Evan O'Donnell; Bjoern Chapuy; Kunihiko Takeyama; Donna Neuberg; Todd R Golub; Jeffery L Kutok; Margaret A Shipp
Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.
Blood 2010;116(17):3268-77.
2010: James E Bradner; Raymond Mak; Shyam K Tanguturi; Ralph Mazitschek; Stephen Haggarty; Kenneth Ross; Cindy Y Chang; Jocelyn Bosco; Nathan West; Elizabeth Morse; Katherine Lin; John Paul Shen; Nicholas P Kwiatkowski; Nele Gheldof; Job Dekker; Daniel J DeAngelo; Steven A Carr; Stuart L Schreiber; Todd R Golub; Benjamin L Ebert
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(28):12617-22.
2010: Trudy Oliver; Kim L Mercer; Leanne C Sayles; James R Burke; Diana Mendus; Katherine S Lovejoy; Mei-Hsin Cheng; Aravind Subramanian; David Mu; Scott Powers; Denise Crowley; Roderick T Bronson; Charles A Whittaker; Arjun Bhutkar; Stephen J Lippard; Todd R Golub; Juergen Thomale; Tyler Jacks; Eric A. Sweet-Cordero
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.
Genes & development 2010;24(8):837-52.
2010: Omar Kabbarah; Cristina Nogueira; Bin Feng; Rosalynn M Nazarian; Marcus W Bosenberg; Min Wu; Kenneth L Scott; Lawrence N Kwong; Yonghong Xiao; Carlos Cordon-Cardo; Scott R Granter; Sridhar Ramaswamy; Todd R Golub; Lyn M Duncan; Stephan N Wagner; Cameron Brennan; Lynda Chin
Integrative genome comparison of primary and metastatic melanomas.
PloS one 2010;5(5):e10770.
2010: Andrea Sboner; Francesca Demichelis; Stefano Calza; Yudi Pawitan; Sunita R Setlur; Yujin Hoshida; Sven Perner; Hans-Olov Adami; Katja Fall; Lorelei A Mucci; Philip W Kantoff; Meir Stampfer; Swen-Olof Andersson; Eberhard Varenhorst; Jan-Erik Johansson; Mark B Gerstein; Todd R Golub; Mark A Rubin; Ove Andrén
Molecular sampling of prostate cancer: a dilemma for predicting disease progression.
BMC medical genomics 2010;3():8.
2009: Madhu S Kumar; Ryan E Pester; Cindy Y Chen; Keara Lane; Christine Chin; Jun Lu; David G Kirsch; Todd R Golub; Tyler Jacks
Dicer1 functions as a haploinsufficient tumor suppressor.
Genes & development 2009;23(23):2700-4.
2009: Cynthia K Hahn; Jacob E Berchuck; Kenneth N Ross; Rose M Kakoza; Karl Clauser; Anna C Schinzel; Linda Ross; Ilene Galinsky; Tina N Davis; Serena J Silver; David E Root; Richard M Stone; Daniel J DeAngelo; Martin Carroll; William C Hahn; Steven A Carr; Todd R Golub; Andrew L Kung; Kimberly Stegmaier
Proteomic and genetic approaches identify Syk as an AML target.
Cancer cell 2009;16(4):281-94.
2009: Yujin Hoshida; Sebastian M B Nijman; Masahiro Kobayashi; Jennifer A Chan; Jean-Philippe Brunet; Derek Chiang; Augusto Villanueva; Philippa Newell; Kenji Ikeda; Masaji Hashimoto; Goro Watanabe; Stacey Gabriel; Scott L Friedman; Hiromitsu Kumada; Josep M Llovet; Todd R Golub
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma.
Cancer research 2009;69(18):7385-92.
2009: Steven M Corsello; Giovanni Roti; Kenneth N Ross; Kwan T Chow; Ilene Galinsky; Daniel J DeAngelo; Richard M Stone; Andrew L Kung; Todd R Golub; Kimberly Stegmaier
Identification of AML1-ETO modulators by chemical genomics.
Blood 2009;113(24):6193-205.
2009: Sadakatsu Ikeda; Aibin He; Sek Won Kong; Jun Lu; Rafael Bejar; Natalya Bodyak; Kyu-Ho Lee; Qing Ma; Peter M Kang; Todd R Golub; William T Pu
MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes.
Molecular and cellular biology 2009;29(8):2193-204.
2009: Srinivas R Viswanathan; Craig H Mermel; Jun Lu; Chi-Wei Lu; Todd R Golub; George Q Daley
microRNA expression during trophectoderm specification.
PloS one 2009;4(7):e6143.
2009: Jinyan Du; Paula Bernasconi; Karl R Clauser; D R Mani; Stephen P Finn; Rameen Beroukhim; Melissa Burns; Bina Julian; Xiao P Peng; Haley Hieronymus; Rebecca L Maglathlin; Timothy A Lewis; Linda M Liau; Phioanh Nghiemphu; Ingo K Mellinghoff; David N Louis; Massimo Loda; Steven A Carr; Andrew L Kung; Todd R Golub
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy.
Nature biotechnology 2009;27(1):77-83.
2008: Yujin Hoshida; Augusto Villanueva; Masahiro Kobayashi; Judit Peix; Derek Chiang; Amy Camargo; Supriya Gupta; Jamie Moore; Matthew J Wrobel; Jim Lerner; Michael Reich; Jennifer A Chan; Jonathan N Glickman; Kenji Ikeda; Masaji Hashimoto; Goro Watanabe; Maria G Daidone; Sasan Roayaie; Myron Schwartz; Swan Thung; Helga B Salvesen; Stacey Gabriel; Vincenzo Mazzaferro; Jordi Bruix; Scott L Friedman; Hiromitsu Kumada; Josep M Llovet; Todd R Golub
Gene expression in fixed tissues and outcome in hepatocellular carcinoma.
The New England journal of medicine 2008;359(19):1995-2004.
2008: Zejuan Li; Jun Lu; Miao Sun; Shuangli Mi; Hao Zhang; Roger T Luo; Ping Chen; Yungui Wang; Ming Yan; Zhijian Qian; Mary Beth Neilly; Jie Jin; Yanming Zhang; Stefan K Bohlander; Dong-Er Zhang; Richard A Larson; Michelle M Le Beau; Michael J Thirman; Todd R Golub; Janet D Rowley; Jianjun Chen
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15535-40.
2008: Winnie F Tam; Ting-Lei Gu; Jing Chen; Benjamin H Lee; Lars Bullinger; Stefan Fröhling; Zhuang Wang; Stefano Monti; Todd R Golub; D Gary Gilliland
Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells.
Blood 2008;112(5):1981-92.
2008: W Nicholas Haining; Benjamin L Ebert; Aravind Subrmanian; E John Wherry; Quentin Eichbaum; John W Evans; Raymond Mak; Stephen Rivoli; Jennifer Pretz; Jill Angelosanto; John S Smutko; Bruce D Walker; Susan M Kaech; Rafi Ahmed; Lee M Nadler; Todd R Golub
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):1859-68.
2008: Cynthia K Hahn; Kenneth N Ross; Ian M Warrington; Ralph Mazitschek; Cindy M Kanegai; Renee D Wright; Andrew L Kung; Todd R Golub; Kimberly Stegmaier
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9751-6.
2008: Guosheng Huang; Rosana Eisenberg; Min Yan; Stefano Monti; Earl Lawrence; Pingfu Fu; Jaclyn Walbroehl; Ester Löwenberg; Todd R Golub; Jaime Merchan; Daniel G Tenen; Sanford D Markowitz; Balazs Halmos
15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancer.
Cancer research 2008;68(13):5040-8.
2008: Sunita R Setlur; Kirsten D Mertz; Yujin Hoshida; Francesca Demichelis; Mathieu Lupien; Sven Perner; Andrea Sboner; Yudi Pawitan; Ove Andrén; Laura A Johnson; Jeff Tang; Hans-Olov Adami; Stefano Calza; Arul M Chinnaiyan; Daniel R Rhodes; Scott A Tomlins; Katja Fall; Lorelei A Mucci; Philip W Kantoff; Meir J Stampfer; Swen-Olof Andersson; Eberhard Varenhorst; Jan-Erik Johansson; Myles Brown; Todd R Golub; Mark A Rubin
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
Journal of the National Cancer Institute 2008;100(11):815-25.
2008: Jun Lu; Shangqin Guo; Benjamin L Ebert; Hao Zhang; Xiao Peng; Jocelyn Bosco; Jennifer Pretz; Rita Schlanger; Judy Y Wang; Raymond H Mak; David M Dombkowski; Frederic I Preffer; David T Scadden; Todd R Golub
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.
Developmental cell 2008;14(6):843-53.
2008: Bridget K Wagner; Toshimori Kitami; Tamara J Gilbert; David Peck; Arvind Ramanathan; Stuart L Schreiber; Todd R Golub; Vamsi K Mootha
Large-scale chemical dissection of mitochondrial function.
Nature biotechnology 2008;26(3):343-51.
2008: Benjamin L Ebert; Naomi Galili; Pablo Tamayo; Jocelyn Bosco; Raymond Mak; Jennifer Pretz; Shyam Tanguturi; Christine Ladd-Acosta; Richard Stone; Todd R Golub; Azra Raza
An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome.
PLoS medicine 2008;5(2):e35.
2008: William M Lin; Alissa C Baker; Rameen Beroukhim; Wendy Winckler; Whei Feng; Jennifer M Marmion; Elisabeth Laine; Heidi Greulich; Hsiuyi Tseng; Casey Gates; F Stephen Hodi; Glenn Dranoff; William R Sellers; Roman K Thomas; Matthew Meyerson; Todd R Golub; Reinhard Dummer; Meenhard Herlyn; Gad Getz; Levi A Garraway
Modeling genomic diversity and tumor dependency in malignant melanoma.
Cancer research 2008;68(3):664-73.
2008: Benjamin L Ebert; Jennifer Pretz; Jocelyn Bosco; Cindy Y Chang; Pablo Tamayo; Naomi Galili; Azra Raza; David E Root; Eyal Attar; Steven R Ellis; Todd R Golub
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen.
Nature 2008;451(7176):335-9.
2008: Kunihiko Takeyama; S Monti; John P Manis; P Dal Cin; Gad Getz; Rameen Beroukhim; Shilpee Dutt; Jon C Aster; Frederick W Alt; Todd R Golub; Margaret A Shipp
Integrative analysis reveals 53BP1 copy loss and decreased expression in a subset of human diffuse large B-cell lymphomas.
Oncogene 2008;27(3):318-22.
2008: Alena A Antipova; Brent R Stockwell; Todd R Golub
Gene expression-based screening for inhibitors of PDGFR signaling.
Genome biology 2008;9(3):R47.
2007: Shuangli Mi; Jun Lu; Miao Sun; Zejuan Li; Hao Zhang; Mary Beth Neilly; Yungui Wang; Zhijian Qian; Jie Jin; Yanming Zhang; Stefan K Bohlander; Michelle M Le Beau; Richard A Larson; Todd R Golub; Janet D Rowley; Jianjun Chen
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19971-6.
2007: Stefan Fröhling; Claudia Scholl; Ross Levine; Marc Loriaux; Titus Boggon; Olivier A Bernard; Roland Berger; Hartmut Döhner; Konstanze Döhner; Benjamin L Ebert; Sewit Teckie; Todd R Golub; Jingrui Jiang; Marcus Schittenhelm; Benjamin H Lee; James D Griffin; Richard M Stone; Michael C Heinrich; Michael W N Deininger; Brian J Druker; D Gary Gilliland
Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles.
Cancer cell 2007;12(6):501-13.
2007: Sadakatsu Ikeda; Sek Won Kong; Jun Lu; Egbert Bisping; Hao Zhang; Paul D Allen; Todd R Golub; Burkert Pieske; William T Pu
Altered microRNA expression in human heart disease.
Physiological genomics 2007;31(3):367-73.
2007: Qing Xu; Pradip K Majumder; Kenneth Ross; Yeonju Shim; Todd R Golub; Massimo Loda; William R Sellers
Identification of prostate cancer modifier pathways using parental strain expression mapping.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(45):17771-6.
2007: Jessica Shin; Stefano Monti; Daniel J Aires; Madeleine Duvic; Todd R Golub; David A Jones; Thomas S Kupper
Lesional gene expression profiling in cutaneous T-cell lymphoma reveals natural clusters associated with disease outcome.
Blood 2007;110(8):3015-27.
2007: Gad Getz; Holger Höfling; Jill P Mesirov; Todd R Golub; Matthew Meyerson; Robert Tibshirani; Eric S Lander
Comment on "The consensus coding sequences of human breast and colorectal cancers".
Science (New York, N.Y.) 2007;317(5844):1500.
2007: Igor Vivanco; NICOLAOS PALASKAS; Chris Tran; Stephen P Finn; Gad Getz; Norman J Kennedy; Jing Jiao; Joshua Rose; Wanling Xie; Massimo Loda; Todd R Golub; Ingo K Mellinghoff; Roger J Davis; Hong Wu; Charles L Sawyers
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.
Cancer cell 2007;11(6):555-69.
2007: Madhu S Kumar; Jun Lu; Kim L Mercer; Todd R Golub; Tyler Jacks
Impaired microRNA processing enhances cellular transformation and tumorigenesis.
Nature genetics 2007;39(5):673-7.
2007: Richard I Sherwood; Cristian Jitianu; Ondine Cleaver; David A Shaywitz; Julia O Lamenzo; Alice E Chen; Todd R Golub; Douglas A Melton
Prospective isolation and global gene expression analysis of definitive and visceral endoderm.
Developmental biology 2007;304(2):541-55.
2007: Todd R Golub
Genomics: global views of leukaemia.
Nature 2007;446(7137):739-40.
2007: Kimberly Stegmaier; Jenny S Wong; Kenneth N Ross; Kwan T Chow; David Peck; Renee D Wright; Stephen L Lessnick; Andrew L Kung; Todd R Golub
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.
PLoS medicine 2007;4(4):e122.
2007: Richard Byers; Dolores Di Vizio; Fionnuala O'connell; Eleni Tholouli; Richard Levenson; Kirk Gossage; Kirk Gossard; David Twomey; Yu Yang; Elisa Benedettini; Joshua Rose; Keith L Ligon; Stephen P Finn; Todd R Golub; Massimo Loda
Semiautomated multiplexed quantum dot-based in situ hybridization and spectral deconvolution.
The Journal of molecular diagnostics : JMD 2007;9(1):20-9.
2007: D Michiel Pegtel; Aravind Subramanian; David Meritt; Ching-Hwa Tsai; Tzung-Shiahn Sheen; Todd R Golub; David A Thorley-Lawson
IFN-alpha-stimulated genes and Epstein-Barr virus gene expression distinguish WHO type II and III nasopharyngeal carcinomas.
Cancer research 2007;67(2):474-81.
2007: Yujin Hoshida; Jean-Philippe Brunet; Pablo Tamayo; Todd R Golub; Jill P Mesirov
Subclass mapping: identifying common subtypes in independent disease data sets.
PloS one 2007;2(11):e1195.
2006: Susumu Kobayashi; Takeshi Shimamura; Stefano Monti; Ulrich Steidl; Christopher J Hetherington; April M Lowell; Todd R Golub; Matthew Meyerson; Daniel G Tenen; Geoffrey I Shapiro; Balazs Halmos
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling.
Cancer research 2006;66(23):11389-98.
2006: Haley Hieronymus; Justin Lamb; Kenneth N Ross; Xiao P Peng; Cristina Clement; Anna Rodina; Maria Nieto; Jinyan Du; Kimberly Stegmaier; Srilakshmi M Raj; Katherine N Maloney; Jon Clardy; William C Hahn; Gabriela Chiosis; Todd R Golub
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.
Cancer cell 2006;10(4):321-30.
2006: Guo Wei; David Twomey; Justin Lamb; Krysta D Schlis; Jyoti Agarwal; Ronald W Stam; Joseph T Opferman; Stephen E Sallan; Monique L den Boer; Rob Pieters; Todd R Golub; Scott A Armstrong
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.
Cancer cell 2006;10(4):331-42.
2006: Justin Lamb; Emily D Crawford; David Peck; Joshua W Modell; Irene C Blat; Matthew J Wrobel; Jim Lerner; Jean-Philippe Brunet; Aravind Subramanian; Kenneth N Ross; Michael Reich; Haley Hieronymus; Guo Wei; Scott A Armstrong; Stephen Haggarty; Paul A Clemons; Ru Wei; Steven A Carr; Eric S Lander; Todd R Golub
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Science (New York, N.Y.) 2006;313(5795):1929-35.
2006: Eleni Tholouli; Judith A Hoyland; Dolores Di Vizio; Fionnuala O'Connell; Sarah A Macdermott; David Twomey; Richard Levenson; John A Liu Yin; Todd R Golub; Massimo Loda; Richard Byers
Imaging of multiple mRNA targets using quantum dot based in situ hybridization and spectral deconvolution in clinical biopsies.
Biochemical and biophysical research communications 2006;348(2):628-36.
2006: Andrei V Krivtsov; David Twomey; Zhaohui Feng; Matthew C Stubbs; Yingzi Wang; Joerg Faber; Jason E Levine; Jing Wang; William C Hahn; D Gary Gilliland; Todd R Golub; Scott A Armstrong
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Nature 2006;442(7104):818-22.
2006: Yana Pikman; Benjamin H Lee; Thomas Mercher; Elizabeth McDowell; Benjamin L Ebert; Maricel Gozo; Adam Cuker; Gerlinde Wernig; Sandra Moore; Ilene Galinsky; Daniel J DeAngelo; Jennifer J Clark; Stephanie J Lee; Todd R Golub; Martha Wadleigh; D Gary Gilliland; Ross Levine
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.
PLoS medicine 2006;3(7):e270.
2006: Richard Smith; Leah A Owen; Deborah J Trem; Jenny S Wong; Jennifer Whangbo; Todd R Golub; Stephen L Lessnick
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma.
Cancer cell 2006;9(5):405-16.
2006: Michael Stanbrough; Glenn J Bubley; Kenneth Ross; Todd R Golub; Mark A Rubin; Trevor M Penning; Phillip G Febbo; Steven P Balk
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer.
Cancer research 2006;66(5):2815-25.
2006: Jean-Pierre Bourquin; Aravind Subramanian; Claudia Langebrake; Dirk Reinhardt; Olivier Bernard; Paola Ballerini; André Baruchel; Hélène Cavé; Nicole Dastugue; Henrik Hasle; Gertjan L Kaspers; michel lessard; Lucienne Michaux; Paresh Vyas; Elisabeth R van Wering; Christian M Zwaan; Todd R Golub; Stuart H Orkin
Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3339-44.
2006: Daniela S Bassères; Elena Levantini; Hongbin Ji; Stefano Monti; Shannon Elf; Tajhal Dayaram; Maris L Fenyus; Olivier Kocher; Todd R Golub; Kwok-Kin Wong; Balazs Halmos; Daniel G Tenen
Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPalpha in mice.
Molecular and cellular biology 2006;26(3):1109-23.
2006: David B Solit; Levi A Garraway; Christine A Pratilas; Ayana Sawai; Gad Getz; Andrea Basso; Qing Ye; Jose Lobo; Yuhong She; Iman Osman; Todd R Golub; Judith Leopold; William R Sellers; Neal Rosen
BRAF mutation predicts sensitivity to MEK inhibition.
Nature 2006;439(7074):358-62.
2006: David Peck; Emily D Crawford; Kenneth N Ross; Kimberly Stegmaier; Todd R Golub; Justin Lamb
A method for high-throughput gene expression signature analysis.
Genome biology 2006;7(7):R61.
2006: Phillip G Febbo; Aaron Thorner; Mark A Rubin; Massimo Loda; Philip W Kantoff; William K Oh; Todd R Golub; Daniel George
Application of oligonucleotide microarrays to assess the biological effects of neoadjuvant imatinib mesylate treatment for localized prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):152-8.
2005: D Michiel Pegtel; Aravind Subramanian; Tzung-Shiahn Sheen; Ching-Hwa Tsai; Todd R Golub; David A Thorley-Lawson
Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasis.
Journal of virology 2005;79(24):15430-42.
2005: Aravind Subramanian; Pablo Tamayo; Vamsi K Mootha; Sayan Mukherjee; Benjamin L Ebert; Michael A Gillette; Amanda Paulovich; Scott L Pomeroy; Todd R Golub; Eric S Lander; Jill P Mesirov
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15545-50.
2005: Kimberly Stegmaier; Steven M Corsello; Kenneth N Ross; Jenny S Wong; Daniel J DeAngelo; Todd R Golub
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
Blood 2005;106(8):2841-8.
2005: Jennifer L Shepard; James F Amatruda; Howard M Stern; Aravind Subramanian; David Finkelstein; James Ziai; K Rose Finley; Kathleen L Pfaff; Candace Hersey; Yi Zhou; Bruce Barut; Matthew Freedman; Charles Lee; Jan Spitsbergen; Donna Neuberg; Gerhard Weber; Todd R Golub; Jonathan N Glickman; Jeffery L Kutok; Jon C Aster; Leonard I Zon
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(37):13194-9.
2005: Friedrich Feuerhake; Jeffery L Kutok; Stefano Monti; Wen Chen; Ann S LaCasce; Giorgio Cattoretti; Paul Kurtin; Geraldine S Pinkus; Laurence de Leval; Nancy Lee Harris; Kerry J Savage; Donna Neuberg; Thomas M Habermann; Riccardo Dalla-Favera; Todd R Golub; Jon C Aster; Margaret A Shipp
NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes.
Blood 2005;106(4):1392-9.
2005: Levi A Garraway; Hans R Widlund; Mark A Rubin; Gad Getz; Aaron J Berger; Sridhar Ramaswamy; Rameen Beroukhim; Danny A Milner; Scott R Granter; Jinyan Du; Charles Lee; Stephan N Wagner; Cheng Li; Todd R Golub; David L Rimm; Matthew Meyerson; David E Fisher; William R Sellers
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
Nature 2005;436(7047):117-22.
2005: Benjamin L Ebert; Michele M Lee; Jennifer L Pretz; Aravind Subramanian; Raymond Mak; Todd R Golub; Colin A Sieff
An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray.
Blood 2005;105(12):4620-6.
2005: Jun Lu; Gad Getz; Eric A Miska; Ezequiel Alvarez-Saavedra; Justin Lamb; David Peck; Eric A. Sweet-Cordero; Benjamin L Ebert; Raymond H Mak; Adolfo Ferrando; James R Downing; Tyler Jacks; H Robert Horvitz; Todd R Golub
MicroRNA expression profiles classify human cancers.
Nature 2005;435(7043):834-8.
2005: Phillip G Febbo; Mark Lowenberg; Aaron R Thorner; Myles Brown; Massimo Loda; Todd R Golub
Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer.
The Journal of urology 2005;173(5):1772-7.
2005: Ross Levine; Martha Wadleigh; Jan Cools; Benjamin L Ebert; Gerlinde Wernig; Brian J P Huntly; Titus Boggon; Iwona Wlodarska; Jennifer J Clark; Sandra Moore; Jennifer Adelsperger; Sumin Koo; Jeffrey C Lee; Stacey Gabriel; Thomas Mercher; Alan D D'Andrea; Stefan Fröhling; Konstanze Döhner; Peter Marynen; Peter Vandenberghe; Ruben A Mesa; Ayalew Tefferi; James D Griffin; Michael J Eck; William R Sellers; Matthew Meyerson; Todd R Golub; Stephanie J Lee; D Gary Gilliland
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Cancer cell 2005;7(4):387-97.
2005: Xiaohui Xie; Jun Lu; Edward J Kulbokas; Todd R Golub; Vamsi K Mootha; Kerstin Lindblad-Toh; Eric S Lander; Manolis Kellis
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals.
Nature 2005;434(7031):338-45.
2005: Stefano Monti; Kerry J Savage; Jeffery L Kutok; Friedrich Feuerhake; Paul Kurtin; Martin Mihm; Bingyan Wu; Laura Pasqualucci; Donna Neuberg; Ricardo Aguiar; Paola Dal Cin; Christine Ladd; Geraldine S Pinkus; Gilles SALLES; Nancy Lee Harris; Riccardo Dalla-Favera; Thomas M Habermann; Jon C Aster; Todd R Golub; Margaret A Shipp
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response.
Blood 2005;105(5):1851-61.
2005: Jing Wang; Hiromi Iwasaki; Andrei V Krivtsov; Phillip G Febbo; Aaron R Thorner; Patricia Ernst; Ema Anastasiadou; Jeffery L Kutok; Scott C Kogan; Sandra S Zinkel; Jill K Fisher; Jay L Hess; Todd R Golub; Scott A Armstrong; Koichi Akashi; Stanley J Korsmeyer
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
The EMBO journal 2005;24(2):368-81.
2005: Eric A. Sweet-Cordero; Sayan Mukherjee; Aravind Subramanian; Han You; Jeffrey J Roix; Christine Ladd-Acosta; Jill P Mesirov; Todd R Golub; Tyler Jacks
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.
Nature genetics 2005;37(1):48-55.
2004: Raanan Berger; Phillip G Febbo; Pradip K Majumder; Jean J Zhao; Shayan Mukherjee; Sabina Signoretti; K Thirza Campbell; William R Sellers; Thomas M Roberts; Massimo Loda; Todd R Golub; William C Hahn
Androgen-induced differentiation and tumorigenicity of human prostate epithelial cells.
Cancer research 2004;64(24):8867-75.
2004: Jinyan Du; Hans R Widlund; Martin A Horstmann; Sridhar Ramaswamy; Ken Ross; Wade E Huber; Emi K Nishimura; Todd R Golub; David E Fisher
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.
Cancer cell 2004;6(6):565-76.
2004: Benjamin L Ebert; Todd R Golub
Genomic approaches to hematologic malignancies.
Blood 2004;104(4):923-32.
2004: Todd R Golub
Toward a functional taxonomy of cancer.
Cancer cell 2004;6(2):107-8.
2004: Balazs Halmos; Daniela S Bassères; Stefano Monti; Francesco D'Aló; Tajhal Dayaram; Katalin Ferenczi; Bas J Wouters; Claudia S Huettner; Todd R Golub; Daniel G Tenen
A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer.
Cancer research 2004;64(12):4137-47.
2004: Pradip K Majumder; Phillip G Febbo; Rachel Bikoff; Raanan Berger; Qi Xue; Louis M McMahon; Judith Manola; James Brugarolas; Timothy J McDonnell; Todd R Golub; Massimo Loda; Heidi A Lane; William R Sellers
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
Nature medicine 2004;10(6):594-601.
2004: Ricardo D Coletta; Kimberly Christensen; Kelly J Reichenberger; Justin Lamb; Damian Micomonaco; Lili Huang; Douglas M Wolf; Carsten Müller-Tidow; Todd R Golub; Kiyoshi Kawakami; Heide L Ford
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6478-83.
2004: Jean-Philippe Brunet; Pablo Tamayo; Todd R Golub; Jill P Mesirov
Metagenes and molecular pattern discovery using matrix factorization.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4164-9.
2004: Kimberly Stegmaier; Kenneth N Ross; Sierra A Colavito; Shawn O'Malley; Brent R Stockwell; Todd R Golub
Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.
Nature genetics 2004;36(3):257-63.
2003: Kerry J Savage; Stefano Monti; Jeffery L Kutok; Giorgio Cattoretti; Donna Neuberg; Laurence De Leval; Paul Kurtin; Paola Dal Cin; Christine Ladd; Friedrich Feuerhake; Ricardo Aguiar; Sigui Li; Gilles SALLES; Francoise Berger; Wen Jing; Geraldine S Pinkus; Thomas M Habermann; Riccardo Dalla-Favera; Nancy Lee Harris; Jon C Aster; Todd R Golub; Margaret A Shipp
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.
Blood 2003;102(12):3871-9.
2003: Scott A Armstrong; Todd R Golub; Stanley J Korsmeyer
MLL-rearranged leukemias: insights from gene expression profiling.
Seminars in hematology 2003;40(4):268-73.
2003: Justin Lamb; Sridhar Ramaswamy; Heide L Ford; Bernardo Contreras; Robert V Martinez; Frances S Kittrell; Cynthia A Zahnow; Nick Patterson; Todd R Golub; Mark E Ewen
A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer.
Cell 2003;114(3):323-34.
2003: Vamsi K Mootha; Cecilia M Lindgren; Karl-Fredrik Eriksson; Aravind Subramanian; Smita Sihag; Joseph Lehar; Pere Puigserver; Emma Carlsson; Martin Ridderstråle; Esa Laurila; Nicholas Houstis; Mark J Daly; Nick Patterson; Jill P Mesirov; Todd R Golub; Pablo Tamayo; Bruce M Spiegelman; Eric S Lander; Joel N Hirschhorn; David Altshuler; Leif C Groop
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.
Nature genetics 2003;34(3):267-73.
2003: Pradip K Majumder; Jen Jen Yeh; Daniel J George; Phillip G Febbo; Jennifer Kum; Qi Xue; Rachel Bikoff; Hongfeng Ma; Philip W Kantoff; Todd R Golub; Massimo Loda; William R Sellers
Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7841-6.
2003: Todd R Golub
Mining the genome for combination therapies.
Nature medicine 2003;9(5):510-1.
2003: Catherine L Nutt; D R Mani; Rebecca A Betensky; Pablo Tamayo; J Gregory Cairncross; Christine Ladd; Ute Pohl; Christian Hartmann; Margaret E McLaughlin; Tracy T Batchelor; Peter Black; Andreas von Deimling; Scott L Pomeroy; Todd R Golub; David N Louis
Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.
Cancer research 2003;63(7):1602-7.
2003: Scott A Armstrong; Andrew L Kung; Meghann E Mabon; Lewis B Silverman; Ronald W Stam; Monique L den Boer; Rob Pieters; John H Kersey; Stephen E Sallan; Jonathan A Fletcher; Todd R Golub; James D Griffin; Stanley J Korsmeyer
Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.
Cancer cell 2003;3(2):173-83.
2003: Sayan Mukherjee; Pablo Tamayo; Simon Rogers; Ryan Rifkin; Anna Engle; Colin Campbell; Todd R Golub; Jill P Mesirov
Estimating dataset size requirements for classifying DNA microarray data.
Journal of computational biology : a journal of computational molecular cell biology 2003;10(2):119-42.
2003: Sridhar Ramaswamy; Kenneth N Ross; Eric S Lander; Todd R Golub
A molecular signature of metastasis in primary solid tumors.
Nature genetics 2003;33(1):49-54.
2002: Chang-Zheng Chen; Min Li; David de Graaf; Stefano Monti; Berthold Göttgens; Maria-Jose Sanchez; Eric S Lander; Todd R Golub; Anthony R Green; Harvey Lodish
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15468-73.
2002: Hong Ruan; Philip D G Miles; Christine Ladd; Kenneth Ross; Todd R Golub; Jerrold M Olefsky; Harvey Lodish
Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance.
Diabetes 2002;51(11):3176-88.
2002: Takeshi Kuwata; Celine Gongora; Yuka Kanno; Kazuyasu Sakaguchi; Tomohiko Tamura; Tomohiko Kanno; venkatesha basrur; Robert Martinez; Ettore Appella; Todd R Golub; Keiko Ozato
Gamma interferon triggers interaction between ICSBP (IRF-8) and TEL, recruiting the histone deacetylase HDAC3 to the interferon-responsive element.
Molecular and cellular biology 2002;22(21):7439-48.
2002: David Humpherys; Kevin Eggan; Hidenori Akutsu; Adam Friedman; Konrad Hochedlinger; Ryuzo Yanagimachi; Eric S Lander; Todd R Golub; Rudolf Jaenisch
Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12889-94.
2002: Tao Peng; Todd R Golub; David M Sabatini
The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation.
Molecular and cellular biology 2002;22(15):5575-84.
2002: Gaël G McGill; Martin A Horstmann; Hans R Widlund; Jinyan Du; Gabriela Motyckova; Emi K Nishimura; Yi-Ling Lin; Sridhar Ramaswamy; William Avery; Hanfei Ding; Siobhán A Jordan; Ian J Jackson; Stanley J Korsmeyer; Todd R Golub; David E Fisher
Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.
Cell 2002;109(6):707-18.
2002: Stephen L Lessnick; Caroline S Dacwag; Todd R Golub
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts.
Cancer cell 2002;1(4):393-401.
2002: Hong Ruan; Nir Hacohen; Todd R Golub; Luk Van Parijs; Harvey Lodish
Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory.
Diabetes 2002;51(5):1319-36.
2002: Sridhar Ramaswamy; Todd R Golub
DNA microarrays in clinical oncology.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(7):1932-41.
2002: Sutisak Kitareewan; Ian Pitha-Rowe; David Sekula; Christopher H Lowrey; Michael J Nemeth; Todd R Golub; Sarah J Freemantle; Ethan Dmitrovsky
UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3806-11.
2002: Dinesh Singh; Phillip G Febbo; Kenneth Ross; Donald G Jackson; Judith Manola; Christine Ladd; Pablo Tamayo; Andrew A Renshaw; Anthony V D'Amico; Jerome P Richie; Eric S Lander; Massimo Loda; Philip W Kantoff; Todd R Golub; William R Sellers
Gene expression correlates of clinical prostate cancer behavior.
Cancer cell 2002;1(2):203-9.
2002: Adolfo Ferrando; Donna Neuberg; Jane Staunton; Mignon L Loh; Christine Huard; Susana C Raimondi; Frederick G. Behm; Ching-Hon Pui; James R Downing; D Gary Gilliland; Eric S Lander; Todd R Golub; A Thomas Look
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia.
Cancer cell 2002;1(1):75-87.
2002: Scott L Pomeroy; Pablo Tamayo; Michelle Gaasenbeek; Lisa-Marie Sturla; Michael Angelo; Margaret E McLaughlin; John Y H Kim; Liliana C Goumnerova; Peter Black; Ching Lau; Jeffrey C Allen; David Zagzag; James M Olson; Tom Curran; Cynthia Wetmore; Jaclyn A Biegel; Tomaso Poggio; Shayan Mukherjee; Ryan Rifkin; Andrea Califano; Gustavo Stolovitzky; David N Louis; Jill P Mesirov; Eric S Lander; Todd R Golub
Prediction of central nervous system embryonal tumour outcome based on gene expression.
Nature 2002;415(6870):436-42.
2002: Alena A Antipova; Pablo Tamayo; Todd R Golub
A strategy for oligonucleotide microarray probe reduction.
Genome biology 2002;3(12):RESEARCH0073.
2002: Margaret A Shipp; Kenneth N Ross; Pablo Tamayo; Andrew P Weng; Jeffery L Kutok; Ricardo Aguiar; Michelle Gaasenbeek; Michael Angelo; Michael Reich; Geraldine S Pinkus; Tane S Ray; Margaret A Koval; Kim W Last; Andrew Norton; T Andrew Lister; Jill P Mesirov; Donna Neuberg; Eric S Lander; Jon C Aster; Todd R Golub
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning.
Nature medicine 2002;8(1):68-74.
2002: Scott A Armstrong; Jane E Staunton; Lewis B Silverman; Rob Pieters; Monique L den Boer; Mark D Minden; Stephen E Sallan; Eric S Lander; Todd R Golub; Stanley J Korsmeyer
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.
Nature genetics 2002;30(1):41-7.
2001: Sridhar Ramaswamy; Pablo Tamayo; Ryan Rifkin; Sayan Mukherjee; Chen-Hsiang Yeang; Michael Angelo; Christine Ladd; Michael Reich; E Latulippe; Jill P Mesirov; Tomaso Poggio; W Gerald; Massimo Loda; Eric S Lander; Todd R Golub
Multiclass cancer diagnosis using tumor gene expression signatures.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15149-54.
2001: Arindam Bhattacharjee; W G Richards; J Staunton; Cheng Li; S Monti; P Vasa; C Ladd; Javad Beheshti; R Bueno; M Gillette; Massimo Loda; Griffin Weber; E J Mark; Eric S Lander; W Wong; Bruce E Johnson; Todd R Golub; David J Sugarbaker; Matthew Meyerson
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13790-5.
2001: J E Staunton; DK Slonim; Hilary A Coller; Pablo Tamayo; Michael Angelo; Julie Park; U Scherf; Jae K Lee; W O Reinhold; J N Weinstein; Jill P Mesirov; Eric S Lander; Todd R Golub
Chemosensitivity prediction by transcriptional profiling.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10787-92.
2001: Todd R Golub
Genomic approaches to the pathogenesis of hematologic malignancy.
Current opinion in hematology 2001;8(4):252-61.
2001: L M Johansen; A Iwama; Tracey A Lodie; K Sasaki; D W Felsher; Todd R Golub; Daniel G Tenen
c-Myc is a critical target for c/EBPalpha in granulopoiesis.
Molecular and cellular biology 2001;21(11):3789-806.
2001: Todd R Golub
Genome-wide views of cancer.
The New England journal of medicine 2001;344(8):601-2.
2001: Chen-Hsiang Yeang; Sridhar Ramaswamy; Pablo Tamayo; Sayan Mukherjee; Ryan Rifkin; Michael Angelo; Michael Reich; Eric S Lander; Jill P Mesirov; Todd R Golub
Molecular classification of multiple tumor types.
Bioinformatics (Oxford, England) 2001;17 Suppl 1():S316-22.
2000: Atul Butte; Pablo Tamayo; DK Slonim; Todd R Golub; Isaac S Kohane
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12182-6.
2000: E A Clark; Todd R Golub; Eric S Lander; Richard O Hynes
Genomic analysis of metastasis reveals an essential role for RhoC.
Nature 2000;406(6795):532-5.
2000: Hilary A Coller; Carla Grandori; Pablo Tamayo; T Colbert; Eric S Lander; Robert N Eisenman; Todd R Golub
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3260-5.
1999: Todd R Golub; DK Slonim; Pablo Tamayo; C Huard; Michelle Gaasenbeek; Jill P Mesirov; Hilary A Coller; Mignon L Loh; J R Downing; M A Caligiuri; C D Bloomfield; Eric S Lander
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.
Science (New York, N.Y.) 1999;286(5439):531-7.
1999: Pablo Tamayo; DK Slonim; Jill P Mesirov; Q Zhu; Sutisak Kitareewan; Ethan Dmitrovsky; Eric S Lander; Todd R Golub
Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2907-12.
1998: Mignon L Loh; Lewis B Silverman; ML Young; Donna Neuberg; Todd R Golub; Stephen E Sallan; D Gary Gilliland
Incidence of TEL/AML1 fusion in children with relapsed acute lymphoblastic leukemia.
Blood 1998;92(12):4792-7.
1998: Frank C P Holstege; Ezra Jennings; John J Wyrick; Tong Ihn Lee; Christoph J. Hengartner; Michael R Green; Todd R Golub; Eric S Lander; Richard A Young
Dissecting the regulatory circuitry of a eukaryotic genome.
Cell 1998;95(5):717-28.
1998: L C Wang; Wojciech Swat; Y Fujiwara; L Davidson; J Visvader; F Kuo; Frederick W Alt; D Gary Gilliland; Todd R Golub; Stuart H Orkin
The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow.
Genes & development 1998;12(15):2392-402.
1997: Todd R Golub
TEL gene rearrangements in myeloid malignancy.
Hematology/oncology clinics of North America 1997;11(6):1207-20.
1997: Seisho Takeuchi; Taku Seriu; Claus R Bartram; Todd R Golub; A Reiter; I Miyoshi; D G Gilliland; H Phillip Koeffler
TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia.
Leukemia 1997;11(8):1220-3.
1997: L C Wang; F Kuo; Y Fujiwara; D Gary Gilliland; Todd R Golub; Stuart H Orkin
Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL.
The EMBO journal 1997;16(14):4374-83.
1997: Cord C Uphoff; Roderick MacLeod; S A Denkmann; Todd R Golub; A Borkhardt; Johannes W G Janssen; Hans G Drexler
Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.
Leukemia 1997;11(3):441-7.
1997: Todd R Golub; G F Barker; Kimberly Stegmaier; D G Gilliland
The TEL gene contributes to the pathogenesis of myeloid and lymphoid leukemias by diverse molecular genetic mechanisms.
Current topics in microbiology and immunology 1997;220():67-79.
1996: M Carroll; Michael H Tomasson; G F Barker; Todd R Golub; D Gary Gilliland
The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14845-50.
1996: Thomas Williams McLean; S Ringold; Donna Neuberg; Kimberly Stegmaier; R Tantravahi; Jerome Ritz; H P Koeffler; S Takeuchi; Johannes W G Janssen; Taku Seriu; Claus R Bartram; Stephen E Sallan; D Gary Gilliland; Todd R Golub
TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia.
Blood 1996;88(11):4252-8.
1996: K Okuda; Todd R Golub; D Gary Gilliland; James D Griffin
p210BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines.
Oncogene 1996;13(6):1147-52.
1996: Todd R Golub; Thomas Williams McLean; Kimberly Stegmaier; M Carroll; Michael H Tomasson; D Gary Gilliland
The TEL gene and human leukemia.
Biochimica et biophysica acta 1996;1288(1):M7-10.
1996: Todd R Golub; A Goga; G F Barker; Daniel E H Afar; Jami McLaughlin; S K Bohlander; J D Rowley; Owen N Witte; D Gary Gilliland
Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia.
Molecular and cellular biology 1996;16(8):4107-16.
1996: Scott W Hiebert; W Sun; James Davis; Todd R Golub; Sheila A Shurtleff; Arjan Buijs; James R Downing; Gerard C Grosveld; M F Roussell; D Gary Gilliland; Noel Lenny; S Meyers
The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription.
Molecular and cellular biology 1996;16(4):1349-55.
1996: Kimberly Stegmaier; S Takeuchi; Todd R Golub; S K Bohlander; Claus R Bartram; H P Koeffler
Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia.
Cancer research 1996;56(6):1413-7.
1996: Todd R Golub; G F Barker; Kimberly Stegmaier; D Gary Gilliland
Involvement of the TEL gene in hematologic malignancy by diverse molecular genetic mechanisms.
Current topics in microbiology and immunology 1996;211():279-88.
1995: Y Sato; Y Suto; J Pietenpol; Todd R Golub; D Gary Gilliland; Elizabeth M Davis; Michelle M Le Beau; J M Roberts; Bert Vogelstein; Janet D Rowley
TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies.
Blood 1995;86(4):1525-33.
1995: Todd R Golub; G F Barker; S K Bohlander; Scott W Hiebert; David C Ward; Patricia Bray-Ward; E Morgan; S C Raimondi; J D Rowley; D Gary Gilliland
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4917-21.
1994: Todd R Golub; G F Barker; M Lovett; D Gary Gilliland
Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation.
Cell 1994;77(2):307-16.
1991: M A Bedell; J B Hudson; Todd R Golub; M E Turyk; M Hosken; G D Wilbanks; Laimonis A Laimins
Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation.
Journal of virology 1991;65(5):2254-60.
1990: Janet S Rader; Todd R Golub; J B Hudson; D Patel; M A Bedell; Laimonis A Laimins
In vitro differentiation of epithelial cells from cervical neoplasias resembles in vivo lesions.
Oncogene 1990;5(4):571-6.
1989: M E Turyk; Todd R Golub; N B Wood; J L Hawkins; G D Wilbanks
Growth and characterization of epithelial cells from normal human uterine ectocervix and endocervix.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1989;25(6):544-56.