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Manuela Gomes

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simone silva; C Sousa; P Teixeira; S G Caridade; M Cerqueira; Manuela E Gomes; João F Mano; Alexandra P Marques; E G Popa; Rui L Reis
An investigation of the potential application of chitosan/aloe-based membranes for regenerative medicine.
Ana I Leal; Jinling Ma; Sofia G Caridade; Manuela E Gomes; John A Jansen; Rui L Reis; X Frank Walboomers; Na Yu; João F Mano
Asymmetric PDLLA membranes containing Bioglass® for guided tissue regeneration: characterization and in vitro biological behavior.
Silvia M Mihaila; Rogério P Pirraco; Tommaso Rada; Rui L Reis; Ana M Frias; Manuela E Gomes; Alexandra P Marques
Human adipose tissue-derived SSEA-4 subpopulation multi-differentiation potential towards the endothelial and osteogenic lineages.

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All Publications

2013: simone silva; C Sousa; P Teixeira; S G Caridade; M Cerqueira; Manuela E Gomes; João F Mano; Alexandra P Marques; E G Popa; Rui L Reis
An investigation of the potential application of chitosan/aloe-based membranes for regenerative medicine.
Acta biomaterialia 2013;9(6):6790-7.
2013: Ana I Leal; Jinling Ma; Sofia G Caridade; Manuela E Gomes; John A Jansen; Rui L Reis; X Frank Walboomers; Na Yu; João F Mano
Asymmetric PDLLA membranes containing Bioglass® for guided tissue regeneration: characterization and in vitro biological behavior.
Dental materials : official publication of the Academy of Dental Materials 2013;29(4):427-36.
2013: Silvia M Mihaila; Rogério P Pirraco; Tommaso Rada; Rui L Reis; Ana M Frias; Manuela E Gomes; Alexandra P Marques
Human adipose tissue-derived SSEA-4 subpopulation multi-differentiation potential towards the endothelial and osteogenic lineages.
Tissue engineering. Part A 2013;19(1-2):235-46.
2012: J F Requicha; C A Viegas; C M Albuquerque; J M Azevedo; Rui L Reis; Manuela E Gomes
Effect of anatomical origin and cell passage number on the stemness and osteogenic differentiation potential of canine adipose-derived stem cells.
Stem cell reviews 2012;8(4):1211-22.
2012: Vítor E Santo; Manuela E Gomes; João F Mano; Rui L Reis
Chitosan-chondroitin sulphate nanoparticles for controlled delivery of platelet lysates in bone regenerative medicine.
Journal of tissue engineering and regenerative medicine 2012;6 Suppl 3():s47-59.
2012: Joana Mota; Rui L Reis; X Frank Walboomers; Na Yu; Sofia G Caridade; Manuela E Gomes; John A Jansen; Gisela M Luz; João F Mano
Chitosan/bioactive glass nanoparticle composite membranes for periodontal regeneration.
Acta biomaterialia 2012;8(11):4173-80.
2012: Márcia T Rodrigues; Carlos A Viegas; Isabel R Dias; Manuela E Gomes; Albino Martins; Nuno M. Neves; Rui L Reis
Synergistic effect of scaffold composition and dynamic culturing environment in multilayered systems for bone tissue engineering.
Journal of tissue engineering and regenerative medicine 2012;6(10):e24-30.
2012: Tiago H Silva; RA Sousa; Lara L Reys; Simone S Silva; Anabela Alves; Manuela E Gomes; João F Mano; Elena G Popa; Rui L Reis
Marine algae sulfated polysaccharides for tissue engineering and drug delivery approaches.
Biomatter 2012;2(4):278-89.
2012: A I Rodrigues; Manuela E Gomes; I B Leonor; Rui L Reis
Bioactive starch-based scaffolds and human adipose stem cells are a good combination for bone tissue engineering.
Acta biomaterialia 2012;8(10):3765-76.
2012: Daniela F Coutinho; Manuela E Gomes; Nezamoddin N Kachouie; Nuno M Neves; Rui L Reis; Amir F Ahari; Ali Khademhosseini
An automated two-phase system for hydrogel microbead production.
Biofabrication 2012;4(3):035003.
2012: Vítor E Santo; Ana Rita C Duarte; Manuela E Gomes; João F Mano; Elena G Popa; Rui L Reis
Enhancement of osteogenic differentiation of human adipose derived stem cells by the controlled release of platelet lysates from hybrid scaffolds produced by supercritical fluid foaming.
Journal of controlled release : official journal of the Controlled Release Society 2012;162(1):19-27.
2012: Vítor E Santo; Manuela E Gomes; João F Mano; Rui L Reis
From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering.
Nanomedicine (London, England) 2012;7(7):1045-66.
2012: Daniela F Coutinho; Manuela E Gomes; Nuno M. Neves; Rui L Reis
Development of micropatterned surfaces of poly(butylene succinate) by micromolding for guided tissue engineering.
Acta biomaterialia 2012;8(4):1490-7.
2011: Elena G Popa; Manuela E Gomes; Rui L Reis
Cell delivery systems using alginate--carrageenan hydrogel beads and fibers for regenerative medicine applications.
Biomacromolecules 2011;12(11):3952-61.
2011: Márcia T Rodrigues; Manuela E Gomes; Rui L Reis
Current strategies for osteochondral regeneration: from stem cells to pre-clinical approaches.
Current opinion in biotechnology 2011;22(5):726-33.
2011: Tommaso Rada; Manuela E Gomes; Rui L Reis
A novel method for the isolation of subpopulations of rat adipose stem cells with different proliferation and osteogenic differentiation potentials.
Journal of tissue engineering and regenerative medicine 2011;5(8):655-64.
2011: Sandra M Luna; João F Mano; Manuela E Gomes; simone silva; Rui L Reis
Cell adhesion and proliferation onto chitosan-based membranes treated by plasma surface modification.
Journal of biomaterials applications 2011;26(1):101-16.
2011: Isabel B Leonor; Márcia T Rodrigues; Manuela E Gomes; Rui L Reis
In situ functionalization of wet-spun fibre meshes for bone tissue engineering.
Journal of tissue engineering and regenerative medicine 2011;5(2):104-11.
2011: Pedro P Carvalho; Isabel R Dias; Manuela E Gomes; Rui L Reis; Xiying Wu; Gang Yu; Jeffrey M Gimble
The effect of storage time on adipose-derived stem cell recovery from human lipoaspirates.
Cells, tissues, organs 2011;194(6):494-500.
2010: João T Oliveira; Leandro S Gardel; Tommaso Rada; Luís Martins; Manuela E Gomes; Rui L Reis
Injectable gellan gum hydrogels with autologous cells for the treatment of rabbit articular cartilage defects.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010;28(9):1193-9.
2010: Ana Grenha; Manuela E Gomes; Márcia Rodrigues; Vítor E Santo; João F Mano; Nuno M. Neves; Rui L Reis
Development of new chitosan/carrageenan nanoparticles for drug delivery applications.
Journal of biomedical materials research. Part A 2010;92(4):1265-72.
2010: Kadriye Tuzlakoglu; I Pashkuleva; M T Rodrigues; Manuela E Gomes; Harry van Lenthe; R Müller; Rui L Reis
A new route to produce starch-based fiber mesh scaffolds by wet spinning and subsequent surface modification as a way to improve cell attachment and proliferation.
Journal of biomedical materials research. Part A 2010;92(1):369-77.
2009: Joaquim M Oliveira; simone silva; Patrícia B Malafaya; Marcia T Rodrigues; Noriko Kotobuki; Motohiro Hirose; Manuela E Gomes; João F Mano; Hajime Ohgushi; Rui L Reis
Macroporous hydroxyapatite scaffolds for bone tissue engineering applications: physicochemical characterization and assessment of rat bone marrow stromal cell viability.
Journal of biomedical materials research. Part A 2009;91(1):175-86.
2009: Vítor Espírito Santo; Ana M Frias; Michela Carida; Ranieri Cancedda; Manuela E Gomes; João F Mano; Rui L Reis
Carrageenan-based hydrogels for the controlled delivery of PDGF-BB in bone tissue engineering applications.
Biomacromolecules 2009;10(6):1392-401.
2009: Tommaso Rada; Rui L Reis; Manuela E Gomes
Adipose tissue-derived stem cells and their application in bone and cartilage tissue engineering.
Tissue engineering. Part B, Reviews 2009;15(2):113-25.
2009: P C Bessa; Mariana Cerqueira; T Rada; Manuela E Gomes; Nuno M. Neves; A Nobre; Rui L Reis; M Casal
Expression, purification and osteogenic bioactivity of recombinant human BMP-4, -9, -10, -11 and -14.
Protein expression and purification 2009;63(2):89-94.
2009: Ana M Martins; Quynh P Pham; Patrícia B Malafaya; RA Sousa; Manuela E Gomes; Robert M Raphael; F Kurtis Kasper; Rui L Reis; Antonios G Mikos
The role of lipase and alpha-amylase in the degradation of starch/poly(epsilon-caprolactone) fiber meshes and the osteogenic differentiation of cultured marrow stromal cells.
Tissue engineering. Part A 2009;15(2):295-305.
2008: Marina I Santos; Kadriye Tuzlakoglu; Sabine Fuchs; Manuela E Gomes; Kirsten Peters; Ronald E Unger; Erhan Piskin; Rui L Reis; C James Kirkpatrick
Endothelial cell colonization and angiogenic potential of combined nano- and micro-fibrous scaffolds for bone tissue engineering.
Biomaterials 2008;29(32):4306-13.
2008: simone silva; Antonella Motta; Márcia T Rodrigues; Ana F M Pinheiro; Manuela E Gomes; João F Mano; Rui L Reis; Claudio Migliaresi
Novel genipin-cross-linked chitosan/silk fibroin sponges for cartilage engineering strategies.
Biomacromolecules 2008;9(10):2764-74.
2008: H Jukola; Lila Nikkola; Manuela E Gomes; Federica Chiellini; M Tukiainen; Minna Kellomäki; Emo Chiellini; Rui L Reis; Nureddin Ashammakhi
Development of a bioactive glass fiber reinforced starch-polycaprolactone composite.
Journal of biomedical materials research. Part B, Applied biomaterials 2008;87(1):197-203.
2008: Manuela E Gomes; Helena S Azevedo; A R Moreira; V Ellä; Minna Kellomäki; Rui L Reis
Starch-poly(epsilon-caprolactone) and starch-poly(lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: structure, mechanical properties and degradation behaviour.
Journal of tissue engineering and regenerative medicine 2008;2(5):243-52.
2008: simone silva; Sandra M Luna; Manuela E Gomes; Johan Benesch; Iva Pashkuleva; João F Mano; Rui L Reis
Plasma surface modification of chitosan membranes: characterization and preliminary cell response studies.
Macromolecular bioscience 2008;8(6):568-76.
2007: Ville Ellä; Manuela E Gomes; Rui L Reis; Pertti Törmälä; Minna Kellomäki
Studies of P(L/D)LA 96/4 non-woven scaffolds and fibres; properties, wettability and cell spreading before and after intrusive treatment methods.
Journal of materials science. Materials in medicine 2007;18(6):1253-61.
2007: Nureddin Ashammakhi; Albana Ndreu; Anna Maria Piras; Lila Nikkola; T Sindelar; Hanna Ylikauppila; A Harlin; Manuela E Gomes; Nuno M. Neves; Emo Chiellini; Federica Chiellini; Vasif Hasirci; H Redl; Rui L Reis
Biodegradable nanomats produced by electrospinning: expanding multifunctionality and potential for tissue engineering.
Journal of nanoscience and nanotechnology 2007;7(3):862-82.
2007: J T Oliveira; Aileen Crawford; J M Mundy; A R Moreira; Manuela E Gomes; Paul Hatton; Rui L Reis
A cartilage tissue engineering approach combining starch-polycaprolactone fibre mesh scaffolds with bovine articular chondrocytes.
Journal of materials science. Materials in medicine 2007;18(2):295-302.
2007: Marina I Santos; Sabine Fuchs; Manuela E Gomes; Ronald E Unger; Rui L Reis; C James Kirkpatrick
Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering.
Biomaterials 2007;28(2):240-8.
2006: Joaquim M Oliveira; Márcia T Rodrigues; simone silva; Patrícia B Malafaya; Manuela E Gomes; Carlos A Viegas; Isabel R Dias; Jorge T Azevedo; João F Mano; Rui L Reis
Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: Scaffold design and its performance when seeded with goat bone marrow stromal cells.
Biomaterials 2006;27(36):6123-37.
2006: Manuela E Gomes; Heidi L Holtorf; Rui L Reis; Antonios G Mikos
Influence of the porosity of starch-based fiber mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flow perfusion bioreactor.
Tissue engineering 2006;12(4):801-9.
2006: Manuela E Gomes; Carla M Bossano; Carol M Johnston; Rui L Reis; Antonios G Mikos
In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor.
Tissue engineering 2006;12(1):177-88.
2005: Kadriye Tuzlakoglu; N Bolgen; António J Salgado; Manuela E Gomes; E Piskin; Rui L Reis
Nano- and micro-fiber combined scaffolds: a new architecture for bone tissue engineering.
Journal of materials science. Materials in medicine 2005;16(12):1099-104.
2004: Manuela E Gomes; Rui L Reis
Tissue engineering: key elements and some trends.
Macromolecular bioscience 2004;4(8):737-42.
2004: António J Salgado; Manuela E Gomes; Olga P Coutinho; Rui L Reis
Isolation and osteogenic differentiation of bone-marrow progenitor cells for application in tissue engineering.
Methods in molecular biology (Clifton, N.J.) 2004;238():123-30.
2004: Manuela E Gomes; Patrícia B Malafaya; Rui L Reis
Methodologies for processing biodegradable and natural origin scaffolds for bone and cartilage tissue-engineering applications.
Methods in molecular biology (Clifton, N.J.) 2004;238():65-76.
2003: Manuela E Gomes; Vassilios I Sikavitsas; Esfandiar Behravesh; Rui L Reis; Antonios G Mikos
Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds.
Journal of biomedical materials research. Part A 2003;67(1):87-95.
2003: Patrícia B Malafaya; Manuela E Gomes; António J Salgado; Rui L Reis
Polymer based scaffolds and carriers for bioactive agents from different natural origin materials.
Advances in experimental medicine and biology 2003;534():201-33.
2001: Manuela E Gomes; Rui L Reis; António M Cunha; C A Blitterswijk; Joost D de Bruijn
Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions.
Biomaterials 2001;22(13):1911-7.
2001: Manuela E Gomes; A S Ribeiro; Patrícia B Malafaya; Rui L Reis; António M Cunha
A new approach based on injection moulding to produce biodegradable starch-based polymeric scaffolds: morphology, mechanical and degradation behaviour.
Biomaterials 2001;22(9):883-9.