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Alicia Gómez-Barrio

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María Celeste Vega; José Antonio Escario; Cristina Fonseca-Berzal; Jorge Gálvez; Alicia Gómez-Barrio; Yovani Marrero-Ponce; Alina Montero-Torres; Miriam Rolón; Vicente J Arán
Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug.
Juan A Castillo-Garit; Oremia Del Toro-Cortés; José Antonio Escario; Alicia Gómez-Barrio; Vladimir V Kouznetsov; Yovani Marrero-Ponce; Cristian Ochoa Puentes; Miriam Rolón; Arnold R Romero Bohórquez; Francisco Torrens; Maria C Vega; Concepción Abad
Identification in silico and in vitro of novel trypanosomicidal drug-like compounds.
Fernando A Rojas Ruiz; Diego F Torres Amado; Antonio R Martínez-Fernández; Juan J Nogal-Ruiz; Berta Martín Pérez-Solórzano; Santiago Villabona Estupiñan; Rory N García-Sánchez; Alicia Gómez-Barrio; Vladimir V Kouznetsov
Synthesis and antimalarial activity of new heterocyclic hybrids based on chloroquine and thiazolidinone scaffolds.

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2012: María Celeste Vega; José Antonio Escario; Cristina Fonseca-Berzal; Jorge Gálvez; Alicia Gómez-Barrio; Yovani Marrero-Ponce; Alina Montero-Torres; Miriam Rolón; Vicente J Arán
Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug.
European journal of medicinal chemistry 2012;58():214-27.
2012: Juan A Castillo-Garit; Oremia Del Toro-Cortés; José Antonio Escario; Alicia Gómez-Barrio; Vladimir V Kouznetsov; Yovani Marrero-Ponce; Cristian Ochoa Puentes; Miriam Rolón; Arnold R Romero Bohórquez; Francisco Torrens; Maria C Vega; Concepción Abad
Identification in silico and in vitro of novel trypanosomicidal drug-like compounds.
Chemical biology & drug design 2012;80(1):38-45.
2011: Fernando A Rojas Ruiz; Diego F Torres Amado; Antonio R Martínez-Fernández; Juan J Nogal-Ruiz; Berta Martín Pérez-Solórzano; Santiago Villabona Estupiñan; Rory N García-Sánchez; Alicia Gómez-Barrio; Vladimir V Kouznetsov
Synthesis and antimalarial activity of new heterocyclic hybrids based on chloroquine and thiazolidinone scaffolds.
Bioorganic & medicinal chemistry 2011;19(15):4562-73.
2011: Juan Alberto Castillo-Garit; José Antonio Escario; Alicia Gómez-Barrio; Yovani Marrero-Ponce; Alina Montero; Facundo Pérez-Giménez; Miriam Rolón; Francisco Torrens; Maria Celeste Vega; Vicente J Arán; Alfredo Alvarez Bello; Concepción Abad
Ligand-based discovery of novel trypanosomicidal drug-like compounds: in silico identification and experimental support.
European journal of medicinal chemistry 2011;46(8):3324-30.
2010: Juan Alberto Castillo-Garit; Maria C Vega; Miriam Rolon; Yovani Marrero-Ponce; Vladimir V Kouznetsov; Diego Fernando Amado Torres; Alicia Gómez-Barrio; Alfredo Alvarez Bello; Alina Montero; Francisco Torrens; Facundo Pérez-Giménez
Computational discovery of novel trypanosomicidal drug-like chemicals by using bond-based non-stochastic and stochastic quadratic maps and linear discriminant analysis.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;39(1-3):30-6.
2009: Marisol Vieites; Pablo Smircich; Lucía Guggeri; Edgar Marchán; Alicia Gómez-Barrio; Maribel Navarro; Beatriz Garat; Dinorah Gambino
Synthesis and characterization of a pyridine-2-thiol N-oxide gold(I) complex with potent antiproliferative effect against Trypanosoma cruzi and Leishmania sp. insight into its mechanism of action.
Journal of inorganic biochemistry 2009;103(10):1300-6.
2009: Vladimir V Kouznetsov; Alicia Gómez-Barrio
Recent developments in the design and synthesis of hybrid molecules based on aminoquinoline ring and their antiplasmodial evaluation.
European journal of medicinal chemistry 2009;44(8):3091-113.
2009: Miriam Martins Alho; Rory N García-Sánchez; Juan José Nogal-Ruiz; José Antonio Escario; Alicia Gómez-Barrio; Antonio R Martínez-Fernández; Vicente J Arán
Synthesis and evaluation of 1,1'-hydrocarbylenebis(indazol-3-ols) as potential antimalarial drugs.
ChemMedChem 2009;4(1):78-87.
2008: Alfredo Meneses Marcel; Oscar M Rivera-Borroto; Yovani Marrero-Ponce; Alina Montero; Yanetsy Machado-Tugores; José Antonio Escario; Alicia Gómez-Barrio; David Montero-Pereira; Juan José Nogal; Vladimir V Kouznetsov; Cristian Ochoa Puentes; Arnold R Bohórquez; Ricardo Grau; Francisco Torrens; Froylán Ibarra-Velarde; Vicente J Arán
New antitrichomonal drug-like chemicals selected by bond (edge)-based TOMOCOMD-CARDD descriptors.
Journal of biomolecular screening 2008;13(8):785-94.
2008: Virginia Roldos; Hector Nakayama; Miriam Rolón; Alina Montero-Torres; Fernando Trucco; Susana Torres; Celeste Vega; Yovani Marrero-Ponce; Viviana Heguaburu; Gloria Yaluff; Alicia Gómez-Barrio; Luis Sanabria; Maria Elena Ferreira; Antonieta Rojas de Arias; Enrique Pandolfi
Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: in silico, in vitro and in vivo activity studies.
European journal of medicinal chemistry 2008;43(9):1797-807.
2008: Marisol Vieites; Pablo Smircich; Beatriz Parajón-Costa; Jorge Rodríguez; Verónica Galaz; Claudio Olea-Azar; Lucía Otero; Gabriela Aguirre; Hugo Cerecetto; Mercedes González; Alicia Gómez-Barrio; Beatriz Garat; Dinorah Gambino
Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite-specific fumarate reductase.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2008;13(5):723-35.
2006: Miriam Rolón; Elena M Seco; Celeste Vega; Juan José Nogal; José Antonio Escario; Alicia Gómez-Barrio; Francisco Malpartida
Selective activity of polyene macrolides produced by genetically modified Streptomyces on Trypanosoma cruzi.
International journal of antimicrobial agents 2006;28(2):104-9.
2006: Miriam Rolón; Celeste Vega; José Antonio Escario; Alicia Gómez-Barrio
Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes.
Parasitology research 2006;99(2):103-7.
2006: Mariana Boiani; Lucía Boiani; Ana Denicola; Susana Torres de Ortiz; Elva Serna; Ninfa Vera de Bilbao; Luis Sanabria; Gloria Yaluff; Héctor Nakayama; Antonieta Rojas de Arias; Celeste Vega; Miriam Rolan; Alicia Gómez-Barrio; Hugo Cerecetto; Mercedes Gonzalez
2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents.
Journal of medicinal chemistry 2006;49(11):3215-24.
2006: María Celeste Vega; Alina Montero-Torres; Yovani Marrero-Ponce; Miriam Rolón; Alicia Gómez-Barrio; José Antonio Escario; Vicente J Arán; Juan José Nogal; Alfredo Meneses Marcel; Francisco Torrens
New ligand-based approach for the discovery of antitrypanosomal compounds.
Bioorganic & medicinal chemistry letters 2006;16(7):1898-904.
2005: Alina Montero-Torres; María Celeste Vega; Yovani Marrero-Ponce; Miriam Rolón; Alicia Gómez-Barrio; José Antonio Escario; Vicente J Arán; Antonio R Martínez-Fernández; Alfredo Meneses Marcel
A novel non-stochastic quadratic fingerprints-based approach for the 'in silico' discovery of new antitrypanosomal compounds.
Bioorganic & medicinal chemistry 2005;13(22):6264-75.
2005: Julieta Coro; Rolando Pérez; Hortensia Rodríguez; Margarita Suárez; Celeste Vega; Miriam Rolón; David Montero; Juan José Nogal; Alicia Gómez-Barrio
Synthesis and antiprotozoan evaluation of new alkyl-linked bis(2-thioxo-[1,3,5]thiadiazinan-3-yl) carboxylic acids.
Bioorganic & medicinal chemistry 2005;13(10):3413-21.
2005: Vicente J Arán; Carmen Ochoa; Lucía Boiani; Pablo Buccino; Hugo Cerecetto; Alejandra Gerpe; Mercedes González; David Montero; Juan José Nogal; Alicia Gómez-Barrio; Amaia Azqueta; Adela López de Ceráin; Oscar E Piro; Eduardo E Castellano
Synthesis and biological properties of new 5-nitroindazole derivatives.
Bioorganic & medicinal chemistry 2005;13(9):3197-207.
2005: Juan José Nogal-Ruiz; Alicia Gómez-Barrio; José Antonio Escario; David Montero-Pereira; Antonio R Martínez-Fernández
Effect of piroxicam, metamizol, and S-adenosylmethionine in a murine model of experimental trichomoniasis.
Parasite (Paris, France) 2005;12(1):79-83.
2005: Mercedes Martínez-Grueiro; Consuelo Giménez-Pardo; Alicia Gómez-Barrio; Xavier Franck; Alain Fournet; Reynald Hocquemiller; Bruno Figadère; Nieves Casado-Escribano
Nematocidal and trichomonacidal activities of 2-substituted quinolines.
Farmaco (Società chimica italiana : 1989) 2005;60(3):219-24.
2005: Celeste Vega; Miriam Rolón; Antonio R Martínez-Fernández; José Antonio Escario; Alicia Gómez-Barrio
A new pharmacological screening assay with Trypanosoma cruzi epimastigotes expressing beta-galactosidase.
Parasitology research 2005;95(4):296-8.
2004: Consuelo Giménez-Pardo; Mercedes Martínez-Grueiro; Alicia Gómez-Barrio; Filomena Rodríguez-Caabeiro
Ivermectin resistant and susceptible third-stage larvae of Haemonchus contortus: cholinesterase and phosphatase activities.
Memórias do Instituto Oswaldo Cruz 2004;99(2):223-6.
2004: Vladimir V Kouznetsov; Leonor Y Vargas Méndez; Belsy Tibaduiza; Carmen Ochoa; David Montero Pereira; Juan J Nogal Ruiz; Carlos Fernaéndez Portillo; Susana Muelas Serrano; Alicia Gómez-Barrio; euro orue; Juan Amaro-Luis
4-Aryl(benzyl)amino-4-heteroarylbut-1-enes as building blocks in heterocyclic synthesis. 4. Synthesis of 4, 6-dimethyl-5-nitro(amino)-2-pyridylquinolines and their antiparasitic activities.
Archiv der Pharmazie 2004;337(3):127-32.
2003: Juan José Nogal-Ruiz; Alicia Gómez-Barrio; José Antonio Escario; Antonio R Martínez-Fernández
Effect of Anapsos in a murine model of experimental trichomoniasis.
Parasite (Paris, France) 2003;10(4):303-8.
2003: Consuelo Giménez-Pardo; Mercedes Martínez-Grueiro; Alicia Gómez-Barrio; Filomena Rodríguez-Caabeiro
Cholinesterase and phosphatase activities in adults and infective-stage larvae of levamisole-resistant and levamisole-susceptible isolates of Haemonchus contortus.
Veterinary research communications 2003;27(8):611-23.
2003: Mercedes Martínez-Grueiro; David Montero-Pereira; Consuelo Giménez-Pardo; Juan José Nogal-Ruiz; José Antonio Escario; Alicia Gómez-Barrio
Trichomonas vaginalis: determination of acid phosphatase activity as a pharmacological screening procedure.
The Journal of parasitology 2003;89(5):1076-7.
2003: Juan José Nogal-Ruiz; Alicia Gómez-Barrio; José Antonio Escario; Antonio R Martínez-Fernández
Modulation by Polypodium leucotomos extract of cytokine patterns in experimental trichomoniasis model.
Parasite (Paris, France) 2003;10(1):73-8.
2002: Ana Le-Senne; Susana Muelas-Serrano; Carlos Fernández-Portillo; José Antonio Escario; Alicia Gómez-Barrio
Biological characterization of a beta-galactosidase expressing clone of Trypanosoma cruzi CL strain.
Memórias do Instituto Oswaldo Cruz 2002;97(8):1101-5.
2002: Alicia Gómez-Barrio; Juan José Nogal-Ruiz; David Montero-Pereira; Ester Rodríguez-Gallego; Esperanza Romero-Fernandez; José Antonio Escario
Biological variability in clinical isolates of Trichomonas vaginalis.
Memórias do Instituto Oswaldo Cruz 2002;97(6):893-6.
2002: Susana Muelas; Margarita Suárez; Rolando Pérez; Hortensia Rodríguez; Carmen Ochoa; José Antonio Escario; Alicia Gómez-Barrio
In vitro and in vivo assays of 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives against Trypanosoma cruzi.
Memórias do Instituto Oswaldo Cruz 2002;97(2):269-72.
2002: Susana Muelas-Serrano; JM Pérez-Serrano; Alicia Gómez-Barrio; Vicente J Arán; Filomena Rodríguez-Caabeiro
Ultrastructural alterations induced by nifurtimox and another nitro derivative on epimastigotes of Trypanosoma cruzi.
Parasitology research 2002;88(2):97-101.
2001: Susana Muelas-Serrano; JM Pérez-Serrano; Alicia Gómez-Barrio; Carmen Ochoa; J Martínez; Filomena Rodríguez-Caabeiro
In vitro effects of anti-Trypanosoma cruzi compounds on HSP60 levels.
Parasitology research 2001;87(8):615-8.
2001: RA Martínez Díaz; José Antonio Escario; Juan José Nogal-Ruiz; Alicia Gómez-Barrio
Relationship between biological behaviour and randomly amplified polymorphic DNA profiles of Trypanosoma cruzi strains.
Memórias do Instituto Oswaldo Cruz 2001;96(2):251-6.
2001: Susana Muelas; Rossanna Di Maio; Hugo Cerecetto; Gustavo Seoane; Carmen Ochoa; José Antonio Escario; Alicia Gómez-Barrio
New thiadiazine derivatives with activity against Trypanosoma cruzi amastigotes.
Folia parasitologica 2001;48(2):105-8.
2001: RA Martínez Díaz; José Antonio Escario; Juan José Nogal-Ruiz; Alicia Gómez-Barrio
Biological characterization of Trypanosoma cruzi strains.
Memórias do Instituto Oswaldo Cruz 2001;96(1):53-9.
2000: Susana Muelas-Serrano; Juan José Nogal-Ruiz; Alicia Gómez-Barrio
Setting of a colorimetric method to determine the viability of Trypanosoma cruzi epimastigotes.
Parasitology research 2000;86(12):999-1002.
2000: Susana Muelas-Serrano; Juan José Nogal; RA Martínez Díaz; José Antonio Escario; Antonio R Martínez-Fernández; Alicia Gómez-Barrio
In vitro screening of american plant extracts on Trypanosoma cruzi and trichomonas vaginalis.
Journal of ethnopharmacology 2000;71(1-2):101-7.
2000: RA Martínez Díaz; José Antonio Escario; Juan José Nogal-Ruiz; Alicia Gómez-Barrio
Evaluation of drug activity against intracellular forms of Trypanosoma cruzi employing enzyme immunoassay.
Journal of clinical pharmacy and therapeutics 2000;25(1):43-7.
1999: Carmen Ochoa; E Pérez; Rolando Pérez; Margarita Suárez; Estael Ochoa; Hortensia Rodríguez; Alicia Gómez-Barrio; Susana Muelas; Juan José Nogal; R A Martínez
Synthesis and antiprotozoan properties of new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives.
Arzneimittel-Forschung 1999;49(9):764-9.
1999: Rossanna Di Maio; Hugo Cerecetto; Gustavo Seoane; Carmen Ochoa; Vicente J Arán; E Pérez; Alicia Gómez-Barrio; Susana Muelas
Synthesis and antichagasic properties of new 1,2,6-thiadiazin-3,5-dione 1,1-dioxides and related compounds.
Arzneimittel-Forschung 1999;49(9):759-63.
1995: J A Escario; Alicia Gómez-Barrio; Antonio R Martínez-Fernández
The relationship of experimental pathogenicity in vivo with in vitro cytoadherence and cytotoxicity of 6 different isolates of Trichomonas vaginalis.
International journal for parasitology 1995;25(8):999-1000.
1992: A Herrero; Carmen Ochoa; J Atienza; J Antonio Escario; Alicia Gómez-Barrio; Antonio R Martínez-Fernández
Synthesis and antiprotozoal properties of 1,2,6-thiadiazine 1,1-dioxide derivatives.
Archiv der Pharmazie 1992;325(8):509-14.
1992: J Atienza; R A Martínez Díaz; Alicia Gómez-Barrio; J A Escario; A Herrero; Carmen Ochoa; J Rodríguez
Activity assays of thiadiazine derivatives on Trichomonas vaginalis and amastigote forms of Trypanosoma cruzi.
Chemotherapy 1992;38(6):441-6.
1991: B Mester; R M Claramunt; J Elguero; J Atienza; Alicia Gómez-Barrio; J A Escario
Research for new antichagasic drugs.
Chemical & pharmaceutical bulletin 1991;39(8):1990-3.