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Nicholas Gonatas

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Edward B Lee; Tarik Tihan; Bernd W Scheithauer; Paul J Zhang; Nicholas K Gonatas
Thyroid transcription factor 1 expression in sellar tumors: a histogenetic marker?
Sashank Prasad; Melissa W Ko; Edward B Lee; Nicholas K Gonatas; Matthew B Stern; Steven L Galetta
Supranuclear vertical gaze abnormalities in sporadic Creutzfeldt-Jakob disease.
Nicholas K Gonatas; Anna Stieber; Jacqueline O Gonatas
Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death.

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All Publications

2009: Edward B Lee; Tarik Tihan; Bernd W Scheithauer; Paul J Zhang; Nicholas K Gonatas
Thyroid transcription factor 1 expression in sellar tumors: a histogenetic marker?
Journal of neuropathology and experimental neurology 2009;68(5):482-8.
2007: Sashank Prasad; Melissa W Ko; Edward B Lee; Nicholas K Gonatas; Matthew B Stern; Steven L Galetta
Supranuclear vertical gaze abnormalities in sporadic Creutzfeldt-Jakob disease.
Journal of the neurological sciences 2007;253(1-2):69-72.
2006: Nicholas K Gonatas; Anna Stieber; Jacqueline O Gonatas
Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death.
Journal of the neurological sciences 2006;246(1-2):21-30.
2005: Catherine A Gilchrist; Douglas A Gray; Anna Stieber; Nicholas K Gonatas; Ron R Kopito
Effect of ubiquitin expression on neuropathogenesis in a mouse model of familial amyotrophic lateral sclerosis.
Neuropathology and applied neurobiology 2005;31(1):20-33.
2004: Christoph W Strey; Daniel Spellman; Anna Stieber; Jacqueline O Gonatas; Xiaosong Wang; John D Lambris; Nicholas K Gonatas
Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis.
The American journal of pathology 2004;165(5):1701-18.
2004: Anna Stieber; Jacqueline O Gonatas; Jonni S Moore; Andrew Bantly; HS Yim; Moon Bin Yim; Nicholas K Gonatas
Disruption of the structure of the Golgi apparatus and the function of the secretory pathway by mutants G93A and G85R of Cu, Zn superoxide dismutase (SOD1) of familial amyotrophic lateral sclerosis.
Journal of the neurological sciences 2004;219(1-2):45-53.
2003: Fumio Yamaguchi; Richard S Morrison; Nicholas K Gonatas; Hiroshi Takahashi; Yuichi Sugisaki; Akira Teramoto
Identification of MG-160, a FGF binding medial Golgi sialoglycoprotein, in brain tumors: an index of malignancy in astrocytomas.
International journal of oncology 2003;22(5):1045-9.
2002: Makoto Uesugi; Koichi Okamoto; Makoto Tanaka; Nicholas K Gonatas
Masses of phosphorylated neurofilaments are associated with abnormal golgi apparatus of anterior horn neurons of beta, beta'-iminodipropionitrile-intoxicated rats.
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(2):61-5.
2002: Atsushi Sakurai; Koichi Okamoto; Masamitsu Yaguchi; Yukio Fujita; Yuji Mizuno; Yoichi Nakazato; Nicholas K Gonatas
Pathology of the inferior olivary nucleus in patients with multiple system atrophy.
Acta neuropathologica 2002;103(6):550-4.
2002: Yukio Fujita; Koichi Okamoto; Atsushi Sakurai; Hirofumi Kusaka; Hitoshi Aizawa; Ban Mihara; Nicholas K Gonatas
The Golgi apparatus is fragmented in spinal cord motor neurons of amyotrophic lateral sclerosis with basophilic inclusions.
Acta neuropathologica 2002;103(3):243-7.
2000: K Takamine; Koichi Okamoto; Yukio Fujita; Atsushi Sakurai; Masamitsu Takatama; Nicholas K Gonatas
The involvement of the neuronal Golgi apparatus and trans-Golgi network in the human olivary hypertrophy.
Journal of the neurological sciences 2000;182(1):45-50.
2000: Atsushi Sakurai; Koichi Okamoto; Yukio Fujita; Yoichi Nakazato; K Wakabayashi; H Takahashi; Nicholas K Gonatas
Fragmentation of the Golgi apparatus of the ballooned neurons in patients with corticobasal degeneration and Creutzfeldt-Jakob disease.
Acta neuropathologica 2000;100(3):270-4.
2000: Anna Stieber; Jacqueline O Gonatas; Nicholas K Gonatas
Aggregates of mutant protein appear progressively in dendrites, in periaxonal processes of oligodendrocytes, and in neuronal and astrocytic perikarya of mice expressing the SOD1(G93A) mutation of familial amyotrophic lateral sclerosis.
Journal of the neurological sciences 2000;177(2):114-23.
2000: Yukio Fujita; Koichi Okamoto; Atsushi Sakurai; Nicholas K Gonatas; Asao Hirano
Fragmentation of the Golgi apparatus of the anterior horn cells in patients with familial amyotrophic lateral sclerosis with SOD1 mutations and posterior column involvement.
Journal of the neurological sciences 2000;174(2):137-40.
2000: Jacqueline O Gonatas; Anna Stieber; Nicholas K Gonatas; Albee Messing
The golgi apparatus is present in perisynaptic, subependymal and perivascular processes of astrocytes and in processes of retinal Müller glia.
Brain research 2000;855(1):23-31.
2000: Anna Stieber; Jacqueline O Gonatas; J Collard; J Meier; J Julien; P Schweitzer; Nicholas K Gonatas
The neuronal Golgi apparatus is fragmented in transgenic mice expressing a mutant human SOD1, but not in mice expressing the human NF-H gene.
Journal of the neurological sciences 2000;173(1):63-72.
2000: Anna Stieber; Jacqueline O Gonatas; Nicholas K Gonatas
Aggregation of ubiquitin and a mutant ALS-linked SOD1 protein correlate with disease progression and fragmentation of the Golgi apparatus.
Journal of the neurological sciences 2000;173(1):53-62.
1999: Yukio Fujita; Koichi Okamoto; Atsushi Sakurai; Masakuni Amari; Yoichi Nakazato; Nicholas K Gonatas
Fragmentation of the Golgi apparatus of Betz cells in patients with amyotrophic lateral sclerosis.
Journal of the neurological sciences 1999;163(1):81-5.
1998: Anne-Hélène Monsoro-Burq; Anna Stieber; Martine Bontoux; Nicole M Le Douarin; Nicholas K Gonatas
Environmental factors modulate the size and the secretory activity of the notochord. A study of the Golgi apparatus in avian embryos.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1998;321(8):621-31.
1998: Nicholas K Gonatas; Jacqueline O Gonatas; Anna Stieber
The involvement of the Golgi apparatus in the pathogenesis of amyotrophic lateral sclerosis, Alzheimer's disease, and ricin intoxication.
Histochemistry and cell biology 1998;109(5-6):591-600.
1998: Anna Stieber; Y Chen; S Wei; Zissimos Mourelatos; Jacqueline O Gonatas; K Okamoto; Nicholas K Gonatas
The fragmented neuronal Golgi apparatus in amyotrophic lateral sclerosis includes the trans-Golgi-network: functional implications.
Acta neuropathologica 1998;95(3):245-53.
1998: Jacqueline O Gonatas; Y J Chen; Anna Stieber; Zissimos Mourelatos; Nicholas K Gonatas
Truncations of the C-terminal cytoplasmic domain of MG160, a medial Golgi sialoglycoprotein, result in its partial transport to the plasma membrane and filopodia.
Journal of cell science 1998;111 ( Pt 2)():249-60.
1997: Y J Chen; Nicholas K Gonatas
The Golgi sialoglycoprotein MG160, expressed in Pichia pastoris, does not require complex carbohydrates and sialic acid for secretion and basic fibroblast growth factor binding.
Biochemical and biophysical research communications 1997;234(1):68-72.
1996: Zissimos Mourelatos; Jacqueline O Gonatas; E Cinato; Nicholas K Gonatas
Cloning and sequence analysis of the human MG160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus.
DNA and cell biology 1996;15(12):1121-8.
1996: Ehud Lavi; Q Wang; Susan R Weiss; Nicholas K Gonatas
Syncytia formation induced by coronavirus infection is associated with fragmentation and rearrangement of the Golgi apparatus.
Virology 1996;221(2):325-34.
1996: Zissimos Mourelatos; Nicholas K Gonatas; Anna Stieber; M E Gurney; M C Dal Canto
The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5472-7.
1996: Raymond Scott Turner; L C Kenyon; John Q Trojanowski; Nicholas K Gonatas; Murray Grossman
Clinical, neuroimaging, and pathologic features of progressive nonfluent aphasia.
Annals of neurology 1996;39(2):166-73.
1996: Anna Stieber; Zissimos Mourelatos; Nicholas K Gonatas
In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic.
The American journal of pathology 1996;148(2):415-26.
1995: Anna Stieber; Y Chen; Jacqueline O Gonatas; W Dougall; X Qian; D O'Rourke; A Samanta; Mark I Greene; Nicholas K Gonatas
Identification of a 140 kDa protein of rat presynaptic terminal membranes encompassing the active zones.
Brain research 1995;700(1-2):261-70.
1995: Anna Stieber; Zissimos Mourelatos; Y J Chen; N Le Douarin; Nicholas K Gonatas
MG160, a membrane protein of the Golgi apparatus which is homologous to a fibroblast growth factor receptor and to a ligand for E-selectin, is found only in the Golgi apparatus and appears early in chicken embryo development.
Experimental cell research 1995;219(2):562-70.
1995: Zissimos Mourelatos; Jacqueline O Gonatas; L M Nycum; Nicholas K Gonatas; Jaclyn A Biegel
Assignment of the GLG1 gene for MGF-160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus, to chromosome 16q22-q23 by fluorescence in situ hybridization.
Genomics 1995;28(2):354-5.
1995: Jacqueline O Gonatas; Zissimos Mourelatos; Anna Stieber; William Stratton Lane; J Brosius; Nicholas K Gonatas
MG-160, a membrane sialoglycoprotein of the medial cisternae of the rat Golgi apparatus, binds basic fibroblast growth factor and exhibits a high level of sequence identity to a chicken fibroblast growth factor receptor.
Journal of cell science 1995;108 ( Pt 2)():457-67.
1995: Ehud Lavi; Q Wang; A Stieber; Y Chen; S Weiss; Nicholas K Gonatas
Fragmentation and rearrangement of the Golgi apparatus during MHV infection of L-2 cells.
Advances in experimental medicine and biology 1995;380():103-4.
1994: Nicholas K Gonatas
Rous-Whipple Award Lecture. Contributions to the physiology and pathology of the Golgi apparatus.
The American journal of pathology 1994;145(4):751-61.
1994: Ehud Lavi; Q Wang; Anna Stieber; Nicholas K Gonatas
Polarity of processes with Golgi apparatus in a subpopulation of type I astrocytes.
Brain research 1994;647(2):273-85.
1994: Zissimos Mourelatos; Asao Hirano; Alan C Rosenquist; Nicholas K Gonatas
Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis (ALS). Clinical studies in ALS of Guam and experimental studies in deafferented neurons and in beta,beta'-iminodipropionitrile axonopathy.
The American journal of pathology 1994;144(6):1288-300.
1994: P A Johnston; Anna Stieber; Nicholas K Gonatas
A hypothesis on the traffic of MG160, a medial Golgi sialoglycoprotein, from the trans-Golgi network to the Golgi cisternae.
Journal of cell science 1994;107 ( Pt 3)():529-37.
1993: Zissimos Mourelatos; Anthony T Yachnis; Lucy B Rorke; J Mikol; Nicholas K Gonatas
The Golgi apparatus of motor neurons in amyotrophic lateral sclerosis.
Annals of neurology 1993;33(6):608-15.
1992: Nicholas K Gonatas; Jacqueline O Gonatas; Anna Stieber
Contributions of peroxidase immunocytochemistry in the ultrastructural detection of membrane bound antigens.
Journal of immunological methods 1992;150(1-2):185-91.
1992: Nicholas K Gonatas; Anna Stieber; Zissimos Mourelatos; Y Chen; Jacqueline O Gonatas; S H Appel; A P Hays; W F Hickey; JEAN-JACQUES HAUW
Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis.
The American journal of pathology 1992;140(3):731-7.
1991: Y J Chen; W F Hickey; S G Mezitis; Anna Stieber; E Lavi; Jacqueline O Gonatas; Nicholas K Gonatas
Monoclonal antibody 2H1 detects a 60-65 KD membrane polypeptide of the rough endoplasmic reticulum of neurons and selectively stains cells of several rat tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991;39(5):635-43.
1990: S Croul; S G Mezitis; Anna Stieber; Y J Chen; Jacqueline O Gonatas; B Goud; Nicholas K Gonatas
Immunocytochemical visualization of the Golgi apparatus in several species, including human, and tissues with an antiserum against MG-160, a sialoglycoprotein of rat Golgi apparatus.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1990;38(7):957-63.
1990: Zissimos Mourelatos; H Adler; Asao Hirano; H Donnenfeld; Jacqueline O Gonatas; Nicholas K Gonatas
Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis revealed by organelle-specific antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4393-5.
1989: Anna Stieber; S D Erulkar; Nicholas K Gonatas
A hypothesis for the superior sensitivity of wheat germ agglutinin as a neuroanatomical probe.
Brain research 1989;495(1):131-9.
1989: Ruth Hogue Angeletti; R Y Xu; Jacqueline O Gonatas; Anna Stieber; Nicholas K Gonatas
Identification of a novel protein (G210) specific to the Golgi apparatus.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(8):1177-82.
1989: C H Rhodes; S G Mezitis; Nicholas K Gonatas; B Fleischer
Selective effect of nerve growth factor on some Golgi and lysosomal enzyme activities of rat pheochromocytoma (PC12) cells.
Archives of biochemistry and biophysics 1989;272(1):175-84.
1989: Jacqueline O Gonatas; S G Mezitis; Anna Stieber; B Fleischer; Nicholas K Gonatas
MG-160. A novel sialoglycoprotein of the medial cisternae of the Golgi apparatus [published eeratum appears in J Biol Chem 1989 Mar 5;264(7):4264].
The Journal of biological chemistry 1989;264(1):646-53.
1988: S E Croul; S G Mezitis; Nicholas K Gonatas
An anti-organelle antibody in pathology. The chromatolytic reaction studied with a monoclonal antibody against the Golgi apparatus.
The American journal of pathology 1988;133(2):355-62.
1988: S G Mezitis; C H Rhodes; Anna Stieber; Nicholas K Gonatas; Jacqueline O Gonatas; B Fleischer
The localization of an antiorganelle monoclonal antibody (10A8) in the Golgi apparatus of rat cells.
Annals of the New York Academy of Sciences 1988;551():256-8.
1987: Jacqueline O Gonatas; Nicholas K Gonatas; Anna Stieber; D Louvard
Polypeptides of the Golgi apparatus of neurons from rat brain.
Journal of neurochemistry 1987;49(5):1498-506.
1987: S G Mezitis; Anna Stieber; Nicholas K Gonatas
Quantitative ultrastructural, autoradiographic evidence for the magnitude and early involvement of the Golgi apparatus complex in the endocytosis of wheat germ agglutinin by cultured neuroblastoma.
Journal of cellular physiology 1987;132(3):401-14.
1987: C H Rhodes; Anna Stieber; Nicholas K Gonatas
Transneuronally transported wheat germ agglutinin labels glia as well as neurons in the rat visual system.
The Journal of comparative neurology 1987;261(3):460-5.
1986: C H Rhodes; Anna Stieber; Nicholas K Gonatas
A quantitative electron microscopic study of the intracellular localization of wheat germ agglutinin in retinal neurons.
The Journal of comparative neurology 1986;254(3):287-96.
1985: C H Rhodes; Jacqueline O Gonatas; Nicholas K Gonatas
A quantitative comparison of the efficiency of orthograde axonal transport and transsynaptic transport of iodinated (125I) wheat germ agglutinin (I-WGA) and horseradish peroxidase labeled I-WGA (I-WGA-HRP) in the rat visual system.
Brain research 1985;336(2):376-80.
1984: Anna Stieber; W F Hickey; Ruth Hogue Angeletti; Nicholas K Gonatas
Endocytosis of nerve growth factor by 'differentiated' PC12 cells studied by quantitative ultrastructural autoradiography.
Brain research 1984;310(2):223-34.
1983: W F Hickey; Anna Stieber; Ruth Hogue Angeletti; Jacqueline O Gonatas; Nicholas K Gonatas
Nerve growth factor induced changes in the Golgi apparatus of PC-12 rat pheochromocytoma cells as studied by ligand endocytosis, cytochemical and morphometric methods.
Journal of neurocytology 1983;12(5):751-66.
1982: Ruth Hogue Angeletti; Anna Stieber; Nicholas K Gonatas
Endocytosis of nerve growth factor by PC12 cells studied by quantitative ultrastructural autoradiography.
Brain research 1982;241(1):145-56.
1982: B J Burchanowski; Ruth Hogue Angeletti; Anna Stieber; Jacqueline O Gonatas; Nicholas K Gonatas
In 'undifferentiated' PC12 cells, GERL is not segregated from the Golgi apparatus.
Journal of neurocytology 1982;11(2):323-33.