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William Arend

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

Living Beings

Mice

Disorders

Occupations

Rheumatology

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Co-Publications
Name
12
Smith, Jr., Michael
10
Hunder, Gene
10
Calabrese, Leonard
9
Banda, Nirmal
9
Holers, Michael
9
Michel, Beat
8
Gabay, C
5
Fries, James
5
Guthridge, Carla
3
Gutierrez-Hartmann, Arthur
3
Kraus, Damian
3
Malyak, M
3
Vondracek, Andrea
3
Muggli, Michele
3
Norris, Jill

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Publications

TOP 3
Banda Nirmal K; Wood Allyson K; Takahashi Kazue; Levitt Brandt; Rudd Pauline M; Royle Louise; Abrahams Jodie L; Stahl Gregory L; Holers V Michael; Arend William P
Initiation of the alternative pathway of murine complement by immune complexes is dependent on N-glycans in IgG antibodies.
Arend William P; Palmer Gaby; Gabay Cem
IL-1, IL-18, and IL-33 families of cytokines.
Arend William P; Goldring Mary B
The development of anticytokine therapeutics for rheumatic diseases.

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All Publications

2008: Banda Nirmal K; Wood Allyson K; Takahashi Kazue; Levitt Brandt; Rudd Pauline M; Royle Louise; Abrahams Jodie L; Stahl Gregory L; Holers V Michael; Arend William P
Initiation of the alternative pathway of murine complement by immune complexes is dependent on N-glycans in IgG antibodies.
Arthritis and rheumatism 2008;58(10):3081-9.
2008: Arend William P; Palmer Gaby; Gabay Cem
IL-1, IL-18, and IL-33 families of cytokines.
Immunological reviews 2008;223():20-38.
2008: Arend William P; Goldring Mary B
The development of anticytokine therapeutics for rheumatic diseases.
Arthritis and rheumatism 2008;58(2 Suppl):S102-9.
2007: Banda Nirmal K; Takahashi Kazue; Wood Allyson K; Holers V Michael; Arend William P
Pathogenic complement activation in collagen antibody-induced arthritis in mice requires amplification by the alternative pathway.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):4101-9.
2007: Yu Liping; Wang Jian; O'Dell James R; Oates James; Arend William P; Eisenbarth George S
Anti-dsDNA antibody assay: high specificity and sensitivity with a filtration radioassay in comparison to low specificity with the standard ELISA.
The Journal of rheumatology 2007;34(4):734-9.
2007: Bhatia Shailaja S; Majka Darcy S; Kittelson John M; Parrish Lezlie A; Ferucci Elizabeth D; Deane Kevin D; Arend William P; Rewers Marian; Michael Holers V; Norris Jill M
Rheumatoid factor seropositivity is inversely associated with oral contraceptive use in women without rheumatoid arthritis.
Annals of the rheumatic diseases 2007;66(2):267-9.
2006: Banda Nirmal K; Thurman Joshua M; Kraus Damian; Wood Allyson; Carroll Michael C; Arend William P; Holers V Michael
Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1904-12.
2006: Kuhn Kristine A; Kulik Liudmila; Tomooka Beren; Braschler Kristin J; Arend William P; Robinson William H; Holers V Michael
Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.
The Journal of clinical investigation 2006;116(4):961-73.
2005: Banda Nirmal K; Guthridge Carla; Sheppard Devon; Cairns Kelly S; Muggli Michele; Bech-Otschir Dawadschargal; Dubiel Wolfgang; Arend William P
Intracellular IL-1 receptor antagonist type 1 inhibits IL-1-induced cytokine production in keratinocytes through binding to the third component of the COP9 signalosome.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3608-16.
2005: Ferucci Elizabeth D; Majka Darcy S; Parrish Lezlie A; Moroldo Marta B; Ryan Mary; Passo Murray; Thompson Susan D; Deane Kevin D; Rewers Marian; Arend William P; Glass David N; Norris Jill M; Holers V Michael
Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis.
Arthritis and rheumatism 2005;52(1):239-46.
2004: Mikuls T R; O'Dell J R; Stoner J A; Parrish L A; Arend W P; Norris J M; Holers V M
Association of rheumatoid arthritis treatment response and disease duration with declines in serum levels of IgM rheumatoid factor and anti-cyclic citrullinated peptide antibody.
Arthritis and rheumatism 2004;50(12):3776-82.
2004: Ross Aron D; Banda Nirmal K; Muggli Michele; Arend William P
Enhancement of collagen-induced arthritis in mice genetically deficient in extracellular superoxide dismutase.
Arthritis and rheumatism 2004;50(11):3702-11.
2004: Arend William P; Gabay Cem
Cytokines in the rheumatic diseases.
Rheumatic diseases clinics of North America 2004;30(1):41-67, v-vi.
2003: Fantuzzi Giamila; Banda Nirmal K; Guthridge Carla; Vondracek Andrea; Kim Soo-Hyun; Siegmund Britta; Azam Tania; Sennello Joseph A; Dinarello Charles A; Arend William P
Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.
Journal of leukocyte biology 2003;74(5):889-96.
2003: Banda Nirmal K; Kraus Damian M; Muggli Michele; Bendele Alison; Holers V Michael; Arend William P
Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):2109-15.
2003: Garat Chrystelle; Arend William P
Intracellular IL-1Ra type 1 inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-kappaB pathways.
Cytokine 2003;23(1-2):31-40.
2003: Banda Nirmal K; Vondracek Andrea; Kraus Damian; Dinarello Charles A; Kim Soo-Hyun; Bendele Alison; Senaldi Giorgio; Arend William P
Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):2100-5.
2002: Banda Nirmal K; Kraus Damian; Vondracek Andrea; Huynh Long H; Bendele Alison; Holers V Michael; Arend William P
Mechanisms of effects of complement inhibition in murine collagen-induced arthritis.
Arthritis and rheumatism 2002;46(11):3065-75.
2002: Arend William P
The mode of action of cytokine inhibitors.
The Journal of rheumatology. Supplement 2002;65():16-21.
2002: Arend William P
The balance between IL-1 and IL-1Ra in disease.
Cytokine & growth factor reviews 2002;13(4-5):323-40.
2001: Arend W P
The innate immune system in rheumatoid arthritis.
Arthritis and rheumatism 2001;44(10):2224-34.
2001: McCarthy P J; Arend W P; Kleinschmidt-DeMasters B K
May 2001: 32 year old female with dural mass encircling cervical spinal cord.
Brain pathology (Zurich, Switzerland) 2001;11(4):483-4, 487.
2001: Arend W P
Cytokines and cellular interactions in inflammatory synovitis.
The Journal of clinical investigation 2001;107(9):1081-2.
2001: Arend W P
Cytokine imbalance in the pathogenesis of rheumatoid arthritis: the role of interleukin-1 receptor antagonist.
Seminars in arthritis and rheumatism 2001;30(5 Suppl 2):1-6.
2001: Arend W P
Physiology of cytokine pathways in rheumatoid arthritis.
Arthritis and rheumatism 2001;45(1):101-6.
2000: Arend W P; Guthridge C J
Biological role of interleukin 1 receptor antagonist isoforms.
Annals of the rheumatic diseases 2000;59 Suppl 1():i60-4.
2000: Arend W P; Gabay C
Physiologic role of interleukin-1 receptor antagonist.
Arthritis research 2000;2(4):245-8.
1999: Gabay C; Smith M F; Arend W P
The human intracellular interleukin 1 receptor antagonist promoter appropriately regulates gene expression in keratinocytes and gastrointestinal epithelial cells in vivo.
Cytokine 1999;11(8):561-70.
1999: Gabay C; Porter B; Guenette D; Billir B; Arend W P
Interleukin-4 (IL-4) and IL-13 enhance the effect of IL-1beta on production of IL-1 receptor antagonist by human primary hepatocytes and hepatoma HepG2 cells: differential effect on C-reactive protein production.
Blood 1999;93(4):1299-307.
1998: Malyak M; Smith M F; Abel A A; Hance K R; Arend W P
The differential production of three forms of IL-1 receptor antagonist by human neutrophils and monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):2004-10.
1998: Malyak M; Guthridge J M; Hance K R; Dower S K; Freed J H; Arend W P
Characterization of a low molecular weight isoform of IL-1 receptor antagonist.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1997-2003.
1998: Gabay C; Arend W P
Treatment of rheumatoid arthritis with IL-1 inhibitors.
Springer seminars in immunopathology 1998;20(1-2):229-46.
1998: Arend W P; Malyak M; Guthridge C J; Gabay C
Interleukin-1 receptor antagonist: role in biology.
Annual review of immunology 1998;16():27-55.
1997: Gabay C; Porter B; Fantuzzi G; Arend W P
Mouse IL-1 receptor antagonist isoforms: complementary DNA cloning and protein expression of intracellular isoform and tissue distribution of secreted and intracellular IL-1 receptor antagonist in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):5905-13.
1997: Gabay C; Smith M F; Eidlen D; Arend W P
Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein.
The Journal of clinical investigation 1997;99(12):2930-40.
1997: Guthridge C J; Eidlen D; Arend W P; Gutierrez-Hartmann A; Smith M F
Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms.
Molecular and cellular biology 1997;17(3):1118-28.
1997: Jenkins J K; Drong R F; Shuck M E; Bienkowski M J; Slightom J L; Arend W P; Smith M F
Intracellular IL-1 receptor antagonist promoter: cell type-specific and inducible regulatory regions.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):748-55.
1995: Svenson M; Nedergaard S; Heegaard P M; Whisenand T D; Arend W P; Bendtzen K
Differential binding of human interleukin-1 (IL-1) receptor antagonist to natural and recombinant soluble and cellular IL-1 type I receptors.
European journal of immunology 1995;25(10):2842-50.
1995: Arend W P; Dayer J M
Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis.
Arthritis and rheumatism 1995;38(2):151-60.
1995: Arend W P
Inhibiting the effects of cytokines in human diseases.
Advances in internal medicine 1995;40():365-94.
1994: Voelkel N F; Tuder R M; Bridges J; Arend W P
Interleukin-1 receptor antagonist treatment reduces pulmonary hypertension generated in rats by monocrotaline.
American journal of respiratory cell and molecular biology 1994;11(6):664-75.
1994: Arend W P; Malyak M; Smith M F; Whisenand T D; Slack J L; Sims J E; Giri J G; Dower S K
Binding of IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(10):4766-74.
1994: Smith M F; Eidlen D; Arend W P; Gutierrez-Hartmann A
LPS-induced expression of the human IL-1 receptor antagonist gene is controlled by multiple interacting promoter elements.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(8):3584-93.
1994: Arend W P; Leung D Y
IgG induction of IL-1 receptor antagonist production by human monocytes.
Immunological reviews 1994;139():71-8.
1994: Firestein G S; Boyle D L; Yu C; Paine M M; Whisenand T D; Zvaifler N J; Arend W P
Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis.
Arthritis and rheumatism 1994;37(5):644-52.
1994: Jenkins J K; Malyak M; Arend W P
The effects of interleukin-10 on interleukin-1 receptor antagonist and interleukin-1 beta production in human monocytes and neutrophils.
Lymphokine and cytokine research 1994;13(1):47-54.
1994: Malyak M; Smith M F; Abel A A; Arend W P
Peripheral blood neutrophil production of interleukin-1 receptor antagonist and interleukin-1 beta.
Journal of clinical immunology 1994;14(1):20-30.
1993: Jenkins J K; Arend W P
Interleukin 1 receptor antagonist production in human monocytes is induced by IL-1 alpha, IL-3, IL-4 and GM-CSF.
Cytokine 1993;5(5):407-15.
1993: Janson R W; King T E; Hance K R; Arend W P
Enhanced production of IL-1 receptor antagonist by alveolar macrophages from patients with interstitial lung disease.
The American review of respiratory disease 1993;148(2):495-503.
1993: Kutsch C L; Norris D A; Arend W P
Tumor necrosis factor-alpha induces interleukin-1 alpha and interleukin-1 receptor antagonist production by cultured human keratinocytes.
The Journal of investigative dermatology 1993;101(1):79-85.
1993: Malyak M; Swaney R E; Arend W P
Levels of synovial fluid interleukin-1 receptor antagonist in rheumatoid arthritis and other arthropathies. Potential contribution from synovial fluid neutrophils.
Arthritis and rheumatism 1993;36(6):781-9.
1993: Patterson D; Jones C; Hart I; Bleskan J; Berger R; Geyer D; Eisenberg S P; Smith M F; Arend W P
The human interleukin-1 receptor antagonist (IL1RN) gene is located in the chromosome 2q14 region.
Genomics 1993;15(1):173-6.
1993: Arend W P
Interleukin-1 receptor antagonist.
Advances in immunology 1993;54():167-227.
1992: Smith M F; Eidlen D; Brewer M T; Eisenberg S P; Arend W P; Gutierrez-Hartmann A
Human IL-1 receptor antagonist promoter. Cell type-specific activity and identification of regulatory regions.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(6):2000-7.
1992: Emlen W; Holers V M; Arend W P; Kotzin B
Regulation of nuclear antigen expression on the cell surface of human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(10):3042-8.
1992: Bigler C F; Norris D A; Weston W L; Arend W P
Interleukin-1 receptor antagonist production by human keratinocytes.
The Journal of investigative dermatology 1992;98(1):38-44.
1991: Janson R W; Hance K R; Arend W P
Production of IL-1 receptor antagonist by human in vitro-derived macrophages. Effects of lipopolysaccharide and granulocyte-macrophage colony-stimulating factor.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4218-23.
1991: Arend W P
Interleukin 1 receptor antagonist. A new member of the interleukin 1 family.
The Journal of clinical investigation 1991;88(5):1445-51.
1991: Arend W P; Coll B P
Interaction of recombinant monocyte-derived interleukin 1 receptor antagonist with rheumatoid synovial cells.
Cytokine 1991;3(5):407-13.
1991: Arend W P; Smith M F; Janson R W; Joslin F G
IL-1 receptor antagonist and IL-1 beta production in human monocytes are regulated differently.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(5):1530-6.
1991: Malyak M; Joslin F G; Verderber E L; Eisenberg S P; Arend W P
IL-1ra ELISA: reduction and alkylation of synovial fluid eliminates interference by IgM rheumatoid factors.
Journal of immunological methods 1991;140(2):281-8.
1991: Arend W P; Malyak M; Bigler C F; Smith M F; Janson R W
The biological role of naturally-occurring cytokine inhibitors.
British journal of rheumatology 1991;30 Suppl 2():49-52.
1990: Janson R W; Joslin F G; Arend W P
The effects of differentiating agents on IL-1 beta production in cultured human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(7):2161-6.
1990: Hunder G G; Arend W P; Bloch D A; Calabrese L H; Fauci A S; Fries J F; Leavitt R Y; Lie J T; Lightfoot R W; Masi A T
The American College of Rheumatology 1990 criteria for the classification of vasculitis. Introduction.
Arthritis and rheumatism 1990;33(8):1065-7.
1990: Fries J F; Hunder G G; Bloch D A; Michel B A; Arend W P; Calabrese L H; Fauci A S; Leavitt R Y; Lie J T; Lightfoot R W
The American College of Rheumatology 1990 criteria for the classification of vasculitis. Summary.
Arthritis and rheumatism 1990;33(8):1135-6.
1990: Hunder G G; Bloch D A; Michel B A; Stevens M B; Arend W P; Calabrese L H; Edworthy S M; Fauci A S; Leavitt R Y; Lie J T
The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis.
Arthritis and rheumatism 1990;33(8):1122-8.
1990: Mills J A; Michel B A; Bloch D A; Calabrese L H; Hunder G G; Arend W P; Edworthy S M; Fauci A S; Leavitt R Y; Lie J T
The American College of Rheumatology 1990 criteria for the classification of Henoch-Schönlein purpura.
Arthritis and rheumatism 1990;33(8):1114-21.
1990: Calabrese L H; Michel B A; Bloch D A; Arend W P; Edworthy S M; Fauci A S; Fries J F; Hunder G G; Leavitt R Y; Lie J T
The American College of Rheumatology 1990 criteria for the classification of hypersensitivity vasculitis.
Arthritis and rheumatism 1990;33(8):1108-13.
1990: Leavitt R Y; Fauci A S; Bloch D A; Michel B A; Hunder G G; Arend W P; Calabrese L H; Fries J F; Lie J T; Lightfoot R W
The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis.
Arthritis and rheumatism 1990;33(8):1101-7.
1990: Masi A T; Hunder G G; Lie J T; Michel B A; Bloch D A; Arend W P; Calabrese L H; Edworthy S M; Fauci A S; Leavitt R Y
The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis).
Arthritis and rheumatism 1990;33(8):1094-100.
1990: Bloch D A; Michel B A; Hunder G G; McShane D J; Arend W P; Calabrese L H; Edworthy S M; Fauci A S; Fries J F; Leavitt R Y
The American College of Rheumatology 1990 criteria for the classification of vasculitis. Patients and methods.
Arthritis and rheumatism 1990;33(8):1068-73.
1990: Arend W P; Michel B A; Bloch D A; Hunder G G; Calabrese L H; Edworthy S M; Fauci A S; Leavitt R Y; Lie J T; Lightfoot R W
The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis.
Arthritis and rheumatism 1990;33(8):1129-34.
1990: Lightfoot R W; Michel B A; Bloch D A; Hunder G G; Zvaifler N J; McShane D J; Arend W P; Calabrese L H; Leavitt R Y; Lie J T
The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa.
Arthritis and rheumatism 1990;33(8):1088-93.
1990: Arend W P; Welgus H G; Thompson R C; Eisenberg S P
Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.
The Journal of clinical investigation 1990;85(5):1694-7.
1990: Arend W P; Dayer J M
Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis.
Arthritis and rheumatism 1990;33(3):305-15.
1990: Eisenberg S P; Evans R J; Arend W P; Verderber E; Brewer M T; Hannum C H; Thompson R C
Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist.
Nature 1990;343(6256):341-6.
1990: Hannum C H; Wilcox C J; Arend W P; Joslin F G; Dripps D J; Heimdal P L; Armes L G; Sommer A; Eisenberg S P; Thompson R C
Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor.
Nature 1990;343(6256):336-40.
1990: Arend W P
Interleukin-1 receptor antagonist: discovery, structure and properties.
Progress in growth factor research 1990;2(4):193-205.
1989: Arend W P; Joslin F G; Thompson R C; Hannum C H
An IL-1 inhibitor from human monocytes. Production and characterization of biologic properties.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(6):1851-8.
1989: Arend W P; Gordon D F; Wood W M; Janson R W; Joslin F G; Jameel S
IL-1 beta production in cultured human monocytes is regulated at multiple levels.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(1):118-26.
1989: Arend W P; Massoni R J; Niemann M A; Giclas P C
Absence of induction of IL-1 production in human monocytes by complement fragments.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(1):173-8.
1988: Arend W P; D'Angelo S; Joslin F G
Regulation of interleukin 1 production in human monocytes. I. Effects of gamma-interferon and cycloheximide.
Clinical and experimental immunology 1988;74(3):377-81.
1986: Arend W P; Massoni R J
Characteristics of bacterial lipopolysaccharide induction of interleukin 1 synthesis and secretion by human monocytes.
Clinical and experimental immunology 1986;64(3):656-64.
1985: Arend W P; Joslin F G; Massoni R J
Effects of immune complexes on production by human monocytes of interleukin 1 or an interleukin 1 inhibitor.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(6):3868-75.
1981: Arend W P; Massoni R J
The effect of complement in adherent immune complexes on Fc and C3 receptor expression in human monocytes.
Immunology 1981;44(4):717-25.

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