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Xiaohua Gong

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TOP 3
Chun-hong Xia; Thomas W White; Bo Chang; Catherine Cheng; Adam M DeRosa; Xiaohua Gong
Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2.
Chun-hong Xia; Bruce Beutler; Xin Du; Haiquan Liu; Eric Lu; Xiaohua Gong
The role of Vldlr in intraretinal angiogenesis in mice.
Catherine Cheng; Xiaohua Gong
Diverse roles of Eph/ephrin signaling in the mouse lens.

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All Publications

2012: Chun-hong Xia; Thomas W White; Bo Chang; Catherine Cheng; Adam M DeRosa; Xiaohua Gong
Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2.
PloS one 2012;7(12):e52894.
2011: Chun-hong Xia; Bruce Beutler; Xin Du; Haiquan Liu; Eric Lu; Xiaohua Gong
The role of Vldlr in intraretinal angiogenesis in mice.
Investigative ophthalmology & visual science 2011;52(9):6572-9.
2011: Catherine Cheng; Xiaohua Gong
Diverse roles of Eph/ephrin signaling in the mouse lens.
PloS one 2011;6(11):e28147.
2010: Catherine Cheng; Chun-hong Xia; Qingling Huang; Linlin Ding; Joseph Horwitz; Xiaohua Gong
Altered chaperone-like activity of alpha-crystallins promotes cataractogenesis.
The Journal of biological chemistry 2010;285(52):41187-93.
2010: Haiquan Liu; Meng Wang; Chun-hong Xia; Xin Du; John G Flannery; Kevin D Ridge; Bruce Beutler; Xiaohua Gong
Severe retinal degeneration caused by a novel rhodopsin mutation.
Investigative ophthalmology & visual science 2010;51(2):1059-65.
2010: Lin Li; Catherine Cheng; Chun-hong Xia; Thomas W White; Daniel A Fletcher; Xiaohua Gong
Connexin mediated cataract prevention in mice.
PloS one 2010;5(9):.
2010: Chun-hong Xia; Zipora Yablonka-Reuveni; Xiaohua Gong
LRP5 is required for vascular development in deeper layers of the retina.
PloS one 2010;5(7):e11676.
2009: Adam M DeRosa; Gülistan Meşe; Leping Li; Caterina Sellitto; Peter R Brink; Xiaohua Gong; Thomas W White
The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium.
Experimental cell research 2009;315(6):1063-75.
2008: Catherine Cheng; Chun-hong Xia; Lin Li; Thomas W White; Joycelyn Niimi; Xiaohua Gong
Gap junction communication influences intercellular protein distribution in the lens.
Experimental eye research 2008;86(6):966-74.
2008: Chun-Hong Xia; Haiquan Liu; Debra Cheung; Meng Wang; Catherine Cheng; Xin Du; Bo Chang; Bruce Beutler; Xiaohua Gong
A model for familial exudative vitreoretinopathy caused by LPR5 mutations.
Human molecular genetics 2008;17(11):1605-12.
2008: Lin Li; Bo Chang; Catherine Cheng; Da Chang; Norman L Hawes; Chun-hong Xia; Xiaohua Gong
Dense nuclear cataract caused by the gammaB-crystallin S11R point mutation.
Investigative ophthalmology & visual science 2008;49(1):304-9.
2007: Adam M DeRosa; Chun-hong Xia; Xiaohua Gong; Thomas W White
The cataract-inducing S50P mutation in Cx50 dominantly alters the channel gating of wild-type lens connexins.
Journal of cell science 2007;120(Pt 23):4107-16.
2007: Kaijun Wang; Catherine Cheng; Lin Li; Haiquan Liu; Qingling Huang; Chun-hong Xia; Ke Yao; Peiqing Sun; Joseph Horwitz; Xiaohua Gong
GammaD-crystallin associated protein aggregation and lens fiber cell denucleation.
Investigative ophthalmology & visual science 2007;48(8):3719-28.
2007: Xiaohua Gong; Catherine Cheng; Chun-hong Xia
Connexins in lens development and cataractogenesis.
The Journal of membrane biology 2007;218(1-3):9-12.
2006: Chun-hong Xia; Catherine Cheng; Qingling Huang; Debra Cheung; Lin Li; Irene Dunia; Lucio E Benedetti; Joseph Horwitz; Xiaohua Gong
Absence of alpha3 (Cx46) and alpha8 (Cx50) connexins leads to cataracts by affecting lens inner fiber cells.
Experimental eye research 2006;83(3):688-96.
2006: Irene Dunia; Christian Cibert; Xiaohua Gong; Chun-hong Xia; Michel Recouvreur; Essy Levy; Nalin M Kumar; Hans Bloemendal; Ennio-Lucio Benedetti
Structural and immunocytochemical alterations in eye lens fiber cells from Cx46 and Cx50 knockout mice.
European journal of cell biology 2006;85(8):729-52.
2006: Chun-hong Xia; Haiquan Liu; Bo Chang; Catherine Cheng; Debra Cheung; Meng Wang; Qingling Huang; Joseph Horwitz; Xiaohua Gong
Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency.
Investigative ophthalmology & visual science 2006;47(7):3004-10.
2006: Chun-hong Xia; Debra Cheung; Adam M DeRosa; Bo Chang; Woo-Kuen Lo; Thomas W White; Xiaohua Gong
Knock-in of alpha3 connexin prevents severe cataracts caused by an alpha8 point mutation.
Journal of cell science 2006;119(Pt 10):2138-44.
2006: Chun-hong Xia; Haiquan Liu; Debra Cheung; Catherine Cheng; Eddie Wang; Xin Du; Bruce Beutler; Woo-Kuen Lo; Xiaohua Gong
Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis.
Development (Cambridge, England) 2006;133(10):2033-40.
2006: Chun-hong Xia; Haiquan Liu; Meng Wang; Debra Cheung; Alex Park; Yang Yang; Xin Du; Bo Chang; Bruce Beutler; Xiaohua Gong
Characterization of mouse mutants with abnormal RPE cells.
Advances in experimental medicine and biology 2006;572():95-100.
2005: Haiquan Liu; Xin Du; Meng Wang; Qingling Huang; Linlin Ding; Hayes W McDonald; John R Yates; Bruce Beutler; Joseph Horwitz; Xiaohua Gong
Crystallin {gamma}B-I4F mutant protein binds to {alpha}-crystallin and affects lens transparency.
The Journal of biological chemistry 2005;280(26):25071-8.
2004: Junyuan Gao; Xiurong Sun; Francisco J Martinez-Wittinghan; Xiaohua Gong; Thomas W White; Richard T Mathias
Connections between connexins, calcium, and cataracts in the lens.
The Journal of general physiology 2004;124(4):289-300.
2004: Xin Du; Koichi Tabeta; Kasper Hoebe; Haiquan Liu; Navjiwan Mann; Suzanne Mudd; Karine Crozat; Sosathya Sovath; Xiaohua Gong; Bruce Beutler
Velvet, a dominant Egfr mutation that causes wavy hair and defective eyelid development in mice.
Genetics 2004;166(1):331-40.
2003: Francisco J Martinez-Wittinghan; Caterina Sellitto; Leping Li; Xiaohua Gong; Peter R Brink; Richard T Mathias; Thomas W White
Dominant cataracts result from incongruous mixing of wild-type lens connexins.
The Journal of cell biology 2003;161(5):969-78.
2002: Brian Petrich; Xiaohua Gong; Deborah L Lerner; Xin Wang; Joan Heller Brown; Jeffrey E Saffitz; Yibin Wang
c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes.
Circulation research 2002;91(7):640-7.
2002: Pei Rong; Xin Wang; Ingrid R Niesman; Ying Wu; Lucio E Benedetti; Irene Dunia; Esther Levy; Xiaohua Gong
Disruption of Gja8 (alpha8 connexin) in mice leads to microphthalmia associated with retardation of lens growth and lens fiber maturation.
Development (Cambridge, England) 2002;129(1):167-74.
2001: GJ Baldo; Xiaohua Gong; Francisco J Martinez-Wittinghan; Nalin M Kumar; Norton B Gilula; Richard T Mathias
Gap junctional coupling in lenses from alpha(8) connexin knockout mice.
The Journal of general physiology 2001;118(5):447-56.
2001: Xiaohua Gong; Xin Wang; Jiahuai Han; Ingrid R Niesman; Q Huang; J Horwitz
Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens.
Investigative ophthalmology & visual science 2001;42(3):539-48.
1999: Xiaohua Gong; K Agopian; Nalin M Kumar; Norton B Gilula
Genetic factors influence cataract formation in alpha 3 connexin knockout mice.
Developmental genetics 1999;24(1-2):27-32.
1998: Xiaohua Gong; GJ Baldo; Nalin M Kumar; Norton B Gilula; Richard T Mathias
Gap junctional coupling in lenses lacking alpha3 connexin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15303-8.
1997: Xiaohua Gong; E Li; G Klier; Q Huang; Y Wu; H Lei; Nalin M Kumar; J Horwitz; Norton B Gilula
Disruption of alpha3 connexin gene leads to proteolysis and cataractogenesis in mice.
Cell 1997;91(6):833-43.