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Rocio González-Conejero

Research Profile

Physiology

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Spain

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Pharmacogenetics

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Publications

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Juan J Cerezo-Manchado; Mario Rosafalco; Vicente Vicente; Ana I Antón; Javier Corral; Nuria Garcia-Barberá; Rocio González-Conejero; Ana B Martinez; Virginia Pérez-Andreu; Vanessa Roldán
Creating a genotype-based dosing algorithm for acenocoumarol steady dose.
Virginia Pérez-Andreu; Vanessa Roldán; Salam Salloum-Asfar; Raúl Teruel; Vicente Vicente; Mia Wadelius; Stephane Bourgeois; Javier Corral; Panos Deloukas; Nuria García-Barberá; María José Gómez-Lechón; Rocio González-Conejero; Constantino Martínez
miR-133a regulates vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1), a key protein in the vitamin K cycle.
Ana I Antón; Rocio González-Conejero; Vanessa Roldán; Teresa Quiroga; Beatriz Sánchez-Vega; Javier Corral; Vicente Vicente; Diego Mezzano
Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders.

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All Publications

2013: Juan J Cerezo-Manchado; Mario Rosafalco; Vicente Vicente; Ana I Antón; Javier Corral; Nuria Garcia-Barberá; Rocio González-Conejero; Ana B Martinez; Virginia Pérez-Andreu; Vanessa Roldán
Creating a genotype-based dosing algorithm for acenocoumarol steady dose.
Thrombosis and haemostasis 2013;109(1):146-53.
2012: Virginia Pérez-Andreu; Vanessa Roldán; Salam Salloum-Asfar; Raúl Teruel; Vicente Vicente; Mia Wadelius; Stephane Bourgeois; Javier Corral; Panos Deloukas; Nuria García-Barberá; María José Gómez-Lechón; Rocio González-Conejero; Constantino Martínez
miR-133a regulates vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1), a key protein in the vitamin K cycle.
Molecular medicine (Cambridge, Mass.) 2012;18():1466-72.
2010: Ana I Antón; Rocio González-Conejero; Vanessa Roldán; Teresa Quiroga; Beatriz Sánchez-Vega; Javier Corral; Vicente Vicente; Diego Mezzano
Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders.
Annals of hematology 2010;89(11):1147-54.
2010: Javier Corral; Ana I Antón; Teresa Quiroga; Rocio González-Conejero; Jaime Pereira; Vanessa Roldán; Vicente Vicente; Diego Mezzano
Influence of the F12 -4 C>T polymorphism on hemostatic tests.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2010;21(7):632-9.
2010: Diana Hernández-Romero; Juan M Ruiz Nodar; Francisco Marin; Antonio Tello-Montoliu; Vanessa Roldán; Luis Mainar; Virginia Pérez-Andreu; Ana I Antón; Juan C Bonaque; Mariano Valdés; Vicente Vicente; Rocio González-Conejero
CALU A29809G polymorphism in coronary atherothrombosis: Implications for coronary calcification and prognosis.
Annals of medicine 2010;42(6):439-46.
2010: V Pérez-Andreu; Vanessa Roldán; M F López-Fernández; A I Antón; Ignacio Alberca; Javier Corral; R Montes; N García-Barberá; F Ferrando; Vicente Vicente; Rocio González-Conejero
Pharmacogenetics of acenocoumarol in patients with extreme dose requirements.
Journal of thrombosis and haemostasis : JTH 2010;8(5):1012-7.
2009: Virginia Pérez-Andreu; Vanessa Roldán; Rocio González-Conejero; Diana Hernández-Romero; Vicente Vicente; Francisco Marín
Implications of pharmacogenetics for oral anticoagulants metabolism.
Current drug metabolism 2009;10(6):632-42.
2009: Constantino Martínez; Ana Isabel Antón; Javier Corral; Teresa Quiroga; Olga Panes; María L Lozano; Rocio González-Conejero; Raúl Teruel; Leyre Navarro-Núñez; Jaime Pereira; Diego Mezzano; Vicente Vicente; José Rivera
Genotype-phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause.
British journal of haematology 2009;146(1):95-103.
2009: Virginia Pérez-Andreu; Vanessa Roldán; Ana Isabel Antón; Nuria García-Barberá; Javier Corral; Vicente Vicente; Rocio González-Conejero
Pharmacogenetic relevance of CYP4F2 V433M polymorphism on acenocoumarol therapy.
Blood 2009;113(20):4977-9.
2009: Vanessa Roldán; Adriana Ordoñez; Francisco Marín; Esther Zorio; José M Soria; Antonia Miñano; Francisco España; Rocio González-Conejero; Javier Pineda; Amparo Estellés; Jordi Fontcuberta; Vicente Vicente; Javier Corral
Antithrombin Cambridge II (A384S) supports a role for antithrombin deficiency in arterial thrombosis.
Thrombosis and haemostasis 2009;101(3):483-6.
2008: Vanessa Roldán; Francisco Marin; Rocio González-Conejero; Antonio García-Honrubia; Silvia Martí; Aranzazu Alfaro; Mariano Valdés; Javier Corral; Gregory Y H Lip; Vicente Vicente
Factor VII -323 decanucleotide D/I polymorphism in atrial fibrillation: implications for the prothrombotic state and stroke risk.
Annals of medicine 2008;40(7):553-9.
2008: Rocio González-Conejero; Javier Corral; Vanessa Roldán; Vicente Vicente
Gamma-glutamyl carboxylase R325Q polymorphism on the response of acenocoumarol.
Thrombosis research 2008;122(3):429-31.
2007: Rocio González-Conejero; Javier Corral; Vanessa Roldán; F Ferrer; I Sánchez-Serrano; J J Sánchez-Blanco; Francisco Marin; Vicente Vicente
The genetic interaction between VKORC1 c1173t and calumenin a29809g modulates the anticoagulant response of acenocoumarol.
Journal of thrombosis and haemostasis : JTH 2007;5(8):1701-6.
2007: Leyre Navarro-Núñez; María L Lozano; José Rivera; Javier Corral; Vanessa Roldán; Rocio González-Conejero; Juan A Iniesta; Joan Montaner; Vicente Vicente; Constantino Martínez
The association of the beta1-tubulin Q43P polymorphism with intracerebral hemorrhage in men.
Haematologica 2007;92(4):513-8.
2007: Vanessa Roldán; F Marín; Rocio González-Conejero; J Corral; V Vicente
Prognostic value of annexin A5 -1 C/T polymorphism in a long term follow-up after premature myocardial infarction.
Journal of thrombosis and haemostasis : JTH 2007;5(4):862-3.
2007: Javier Corral; Rocio González-Conejero; David Hernández-Espinosa; Vicente Vicente
Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis.
British journal of haematology 2007;137(2):99-108.
2007: Francisco Marín; Vanessa Roldán; Rocio González-Conejero; Javier Corral
The pharmacogenetics of antiplatelet drugs.
Current opinion in investigational drugs (London, England : 2000) 2007;8(3):213-8.
2007: Javier Corral; José Rivera; José A Guerrero; Antonia Miñano; Ignacio Alberca; David Hernández-Espinosa; Adriana Ordóñez; Constantino Martínez; Leyre Navarro-Núñez; Rocio González-Conejero; María L Lozano; Vicente Vicente
Latent and polymeric antithrombin: clearance and potential thrombotic risk.
Experimental biology and medicine (Maywood, N.J.) 2007;232(2):219-26.
2007: Adriana Ordóñez; Carmen de Cos; Antonia Miñano; Javier Rodríguez; David Hernández-Espinosa; Juan A Muñoz; Rocio González-Conejero; Vicente Vicente; Javier Corral
Coexistence of three genetic risk factors in a Spanish thrombophilic family: Factor V Leiden, prothrombin 20210 and a new type I antithrombin deficiency.
Thrombosis and haemostasis 2007;97(1):153-5.
2006: Rocio González-Conejero; Israel Fernández-Cadenas; Juan A Iniesta; Joan Marti-Fabregas; Victor Obach; José Alvarez-Sabín; Vicente Vicente; Javier Corral; Joan Montaner
Role of fibrinogen levels and factor XIII V34L polymorphism in thrombolytic therapy in stroke patients.
Stroke; a journal of cerebral circulation 2006;37(9):2288-93.
2006: Javier Corral; Rocio González-Conejero; Jose Manuel Soria; Jose Ramón González-Porras; Elena Pérez-Ceballos; Ramón Lecumberri; Vanessa Roldán; Juan Carlos Souto; Antonia Miñano; David Hernández-Espinosa; Ignacio Alberca; Jordi Fontcuberta; Vicente Vicente
A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis.
Blood 2006;108(1):177-83.
2006: Rocio González-Conejero; Francisco Marín; Javier Corral; Vanessa Roldán
Fluctuations in coagulation activity among patients with atrial fibrillation who are stably anticoagulated.
Future cardiology 2006;2(2):197-203.
2005: Vanessa Roldán; Javier Corral; Francisco Marin; Javier Pineda; Vicente Vicente; Rocio González-Conejero
Synergistic association between hypercholesterolemia and the C46T factor XII polymorphism for developing premature myocardial infarction.
Thrombosis and haemostasis 2005;94(6):1294-9.
2005: Francisco Marin; Vanessa Roldán; Rocio González-Conejero; Javier Corral
Pharmacogenetics in cardiovascular antithrombotic therapy.
Current medicinal chemistry. Cardiovascular and hematological agents 2005;3(4):357-64.
2005: Vanessa Roldán; Rocio González-Conejero; Francisco Marin; Javier Pineda; Vicente Vicente; Javier Corral
Five prothrombotic polymorphisms and the prevalence of premature myocardial infarction.
Haematologica 2005;90(3):421-3.
2005: Francisco Marin; Rocio González-Conejero; Kaeng W Lee; Javier Corral; Vanessa Roldán; Francisca López; Francisco Sogorb; Juan Caturla; Gregory Y H Lip; Vicente Vicente
A pharmacogenetic effect of factor XIII valine 34 leucine polymorphism on fibrinolytic therapy for acute myocardial infarction.
Journal of the American College of Cardiology 2005;45(1):25-9.
2004: Vanessa Roldán; J Corral; F Marín; V Vicente; Rocio González-Conejero
Effect of factor VII -323 Del/Ins polymorphism on the daily variability of factor VIIc and INR in steady anticoagulated patients with acenocoumarol.
Journal of thrombosis and haemostasis : JTH 2004;2(12):2264-5.
2004: Vanessa Roldán; Rocio González-Conejero; Francisco Marin; Javier Pineda; Vicente Vicente; Javier Corral
Short alleles of P-selectin glycoprotein ligand-1 protect against premature myocardial infarction.
American heart journal 2004;148(4):602-5.
2004: Juan A Iniesta; Rocio González-Conejero; Claudio Piqueras; Vicente Vicente; Javier Corral
Platelet GP IIIa polymorphism HPA-1 (PlA) protects against subarachnoid hemorrhage.
Stroke; a journal of cerebral circulation 2004;35(10):2282-6.
2004: Francisco Marín; Javier Corral; Vanessa Roldán; Rocio González-Conejero; María Luz del Rey; Francisco Sogorb; Gregory Y H Lip; Vicente Vicente
Factor XIII Val34Leu polymorphism modulates the prothrombotic and inflammatory state associated with atrial fibrillation.
Journal of molecular and cellular cardiology 2004;37(3):699-704.
2004: Rocio González-Conejero; Javier Corral; José A Guerrero; Juan A Iniesta; José Rivera; Felipe de Arriba; Vicente Vicente
Genetic variants of the extra-large stimulatory Gs protein alpha-subunit and risk of thrombotic and haemorrhagic disorders.
British journal of haematology 2004;125(5):621-8.
2004: Javier Corral; James A Huntington; Rocio González-Conejero; Alec Mushunje; M Navarro; Pascual Marco; Vicente Vicente; Robin W Carrell
Mutations in the shutter region of antithrombin result in formation of disulfide-linked dimers and severe venous thrombosis.
Journal of thrombosis and haemostasis : JTH 2004;2(6):931-9.
2004: M D García-Malo; Javier Corral; M González; Carlos Solano; Rocio González-Conejero; María Dolores Caballero; R Pérez; José María Moraleda; Vicente Vicente
Human platelet antigen systems in allogeneic peripheral blood progenitor cell transplantation: effect of human platelet antigen mismatch on platelet engraftment and graft-versus-host disease.
Transfusion 2004;44(5):771-6.
2004: Javier Corral; Rocio González-Conejero; Vicente Vicente
Genetic determinants of platelet function in thromboembolic diseases.
Journal of biological regulators and homeostatic agents 2004;18(2):166-71.
2004: Javier Corral; Rocio González-Conejero; Núria Pujol-Moix; Pere Domenech; Vicente Vicente
Mutation analysis of HPS1, the gene mutated in Hermansky-Pudlak syndrome, in patients with isolated platelet dense-granule deficiency.
Haematologica 2004;89(3):325-9.
2003: Javier Corral; José Rivera; Constantino Martínez; Rocio González-Conejero; Antonia Miñano; Vicente Vicente
Detection of conformational transformation of antithrombin in blood with crossed immunoelectrophoresis: new application for a classical method.
The Journal of laboratory and clinical medicine 2003;142(5):298-305.
2003: Rocio González-Conejero; José Rivera; Gines Escolar; Isabel Zuazu-Jausoro; Vicente Vicente; Javier Corral
Molecular, ultrastructural and functional characterization of a Spanish family with Hermansky-Pudlak syndrome: role of insC974 in platelet function and clinical relevance.
British journal of haematology 2003;123(1):132-8.
2003: Francisco Ayala; Javier Corral; Rocio González-Conejero; Ignacio Sánchez; José María Moraleda; Vicente Vicente
Genetic polymorphisms of platelet adhesive molecules: association with breast cancer risk and clinical presentation.
Breast cancer research and treatment 2003;80(2):145-54.
2003: Vanessa Roldán; Javier Corral; Francisco Marin; José Rivera; Javier Pineda; Rocio González-Conejero; Francisco Sogorb; Vicente Vicente
Role of factor XIII Val34Leu polymorphism in patients <45 years of age with acute myocardial infarction.
The American journal of cardiology 2003;91(10):1242-5.
2003: Juan A Iniesta; Javier Corral; Rocio González-Conejero; Claudio Piqueras; Vicente Vicente
Polymorphisms of platelet adhesive receptors: do they play a role in primary intracerebral hemorrhage?
Cerebrovascular diseases (Basel, Switzerland) 2003;15(1-2):51-5.
2002: Rocio González-Conejero; Javier Corral; Vanessa Roldán; Constantino Martínez; Francisco Marin; José Rivera; Juan A Iniesta; María L Lozano; Pascual Marco; Vicente Vicente
A common polymorphism in the annexin V Kozak sequence (-1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients.
Blood 2002;100(6):2081-6.
2002: Elena Pérez-Ceballos; Javier Corral; Ignacio Alberca; Amparo Vayá; Pilar Llamas; Ramón Montes; Rocio González-Conejero; Vicente Vicente
Prothrombin A19911G and G20210A polymorphisms' role in thrombosis.
British journal of haematology 2002;118(2):610-4.
2002: J Corral; Rocio González-Conejero; C Martínez; J Rivera; María L Lozano; V Vicente
Platelet aggregation through prothrombinase activation induced by non-aggregant doses of platelet agonists.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2002;13(2):95-103.
2001: María L Lozano; Rocio González-Conejero; Javier Corral; José Rivera; Juan A Iniesta; C Martinez; Vicente Vicente
Polymorphisms of P-selectin glycoprotein ligand-1 are associated with neutrophil-platelet adhesion and with ischaemic cerebrovascular disease.
British journal of haematology 2001;115(4):969-76.
2001: Juan A Iniesta; Javier Corral; Rocio González-Conejero; A Díaz Ortuño; M L Martínez Navarro; Vicente Vicente
Role of factor XIII Val 34 Leu polymorphism in patients with migraine.
Cephalalgia : an international journal of headache 2001;21(8):837-41.
2001: Javier Corral; Juan A Iniesta; Rocio González-Conejero; M Villalón; Vicente Vicente
Polymorphisms of clotting factors modify the risk for primary intracranial hemorrhage.
Blood 2001;97(10):2979-82.
2001: C Martínez; J Rivera; Stéphane Loyau; J Corral; Rocio González-Conejero; María L Lozano; Vicente Vicente; Eduardo Anglés-Cano
Binding of recombinant apolipoprotein(a) to human platelets and effect on platelet aggregation.
Thrombosis and haemostasis 2001;85(4):686-93.
2000: J Rivera; María L Lozano; J Corral; Rocio González-Conejero; C Martínez; V Vicente
Platelet GP Ib/IX/V complex: physiological role.
Journal of physiology and biochemistry 2000;56(4):355-65.
2000: Rocio González-Conejero; María L Lozano; J Corral; C Martínez; V Vicente
The TFPI 536C-->T mutation is not associated with increased risk for venous or arterial thrombosis.
Thrombosis and haemostasis 2000;83(5):787-8.
2000: Javier Corral; Rocio González-Conejero; Juan A Iniesta; José Rivera; C Martínez; Vicente Vicente
The FXIII Val34Leu polymorphism in venous and arterial thromboembolism.
Haematologica 2000;85(3):293-7.
2000: Javier Corral; Juan A Iniesta; Rocio González-Conejero; M Villalón; José Rivera; Vicente Vicente
Factor XIII Val34Leu polymorphism in primary intracerebral haemorrhage.
The hematology journal : the official journal of the European Haematology Association / EHA 2000;1(4):269-73.
2000: Francisca Ferrer; José Rivera; Javier Corral; Rocio González-Conejero; Vicente Vicente
Evaluation of leukocyte-depleted platelet concentrates obtained by in-line filtration.
Vox sanguinis 2000;78(4):235-41.
2000: Javier Corral; María L Lozano; Rocio González-Conejero; C Martínez; Juan A Iniesta; José Rivera; Vicente Vicente
A common polymorphism flanking the ATG initiator codon of GPIb alpha does not affect expression and is not a major risk factor for arterial thrombosis.
Thrombosis and haemostasis 2000;83(1):23-8.
1999: Joaquin Gomez Espuch; Javier Corral; Rocio González-Conejero; Francisco J Ortuño; José María Moraleda; Vicente Vicente
Glycoprotein IIb/IIIa expression on hematopoietic stem cells: constitutive expression or platelet adhesion?
Blood 1999;94(9):3271-3.
1999: Juan A Iniesta; Javier Corral; Rocio González-Conejero; José Rivera; Vicente Vicente
Prothrombotic genetic risk factors in patients with coexisting migraine and ischemic cerebrovascular disease.
Headache 1999;39(7):486-9.
1999: Javier Corral; Rocio González-Conejero; J Rivera; Francisco J Ortuño; P Aparicio; Vicente Vicente
Role of the 807 C/T polymorphism of the alpha2 gene in platelet GP Ia collagen receptor expression and function--effect in thromboembolic diseases.
Thrombosis and haemostasis 1999;81(6):951-6.
1999: Javier Corral; Isabel Zuazu-Jausoro; José Rivera; Rocio González-Conejero; F Ferrer; Vicente Vicente
Clinical and analytical relevance of the combination of prothrombin 20210A/A and factor V Leiden: results from a large family.
British journal of haematology 1999;105(2):560-3.
1999: Javier Corral; José Rivera; Rocio González-Conejero; Vicente Vicente
The number of platelet glycoprotein Ia molecules is associated with the genetically linked 807 C/T and HPA-5 polymorphisms.
Transfusion 1999;39(4):372-8.
1999: Vicente Vicente; Rocio González-Conejero; José Rivera; Javier Corral
The prothrombin gene variant 20210A in venous and arterial thromboembolism.
Haematologica 1999;84(4):356-62.
1999: Felipe de Arriba; Javier Corral; Francisco Ayala; I Heras; José María Moraleda; MM Osma; Rocio González-Conejero; Francisco J Ortuño; Vicente Vicente
Autoaggression syndrome resembling acute graft-versus-host disease grade IV after autologous peripheral blood stem cell transplantation for breast cancer.
Bone marrow transplantation 1999;23(6):621-4.
1998: Javier Corral; Rocio González-Conejero; María L Lozano; José Rivera; Vicente Vicente
New alleles of the platelet glycoprotein Ibalpha gene.
British journal of haematology 1998;103(4):997-1003.
1998: Javier Corral; Juan A Iniesta; Rocio González-Conejero; María L Lozano; José Rivera; Vicente Vicente
Migraine and prothrombotic genetic risk factors.
Cephalalgia : an international journal of headache 1998;18(5):257-60.
1998: J Corral; Rocio González-Conejero; María L Lozano; J Rivera; V Vicente
Genetic polymorphisms of factor VII are not associated with arterial thrombosis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1998;9(3):267-72.
1997: Javier Corral; Rocio González-Conejero; José Rivera; Juan A Iniesta; María L Lozano; Vicente Vicente
HPA-1 genotype in arterial thrombosis--role of HPA-1b polymorphism in platelet function.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1997;8(5):284-90.
1997: Juan A Iniesta; Javier Corral; J Fernández-Pardo; Rocio González-Conejero; Vicente Vicente
Factor-V (Arg506 --> Gln) mutation in ischemic cerebrovascular disease.
Haemostasis 1997;27(3):105-11.
1996: Javier Corral; Juan A Iniesta; Rocio González-Conejero; Vicente Vicente
Detection of factor V Leiden from a drop of blood by PCR-SSCP.
Thrombosis and haemostasis 1996;76(5):735-7.