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Rayudu Gopalakrishna

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Usha Gundimeda; David R Hinton; Thomas H McNeill; Jason E Schiffman; Albert A Elhiani; Rayudu Gopalakrishna
Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.
Usha Gundimeda; Tom McNeill; Jason E Schiffman; David R Hinton; Rayudu Gopalakrishna
Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
Usha Gundimeda; Jason Eric Schiffman; Simcha Neeli Gottlieb; Brandon Ian Roth; Rayudu Gopalakrishna
Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase.

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2012: Usha Gundimeda; David R Hinton; Thomas H McNeill; Jason E Schiffman; Albert A Elhiani; Rayudu Gopalakrishna
Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.
The Journal of biological chemistry 2012;287(41):34694-708.
2010: Usha Gundimeda; Tom McNeill; Jason E Schiffman; David R Hinton; Rayudu Gopalakrishna
Green tea polyphenols potentiate the action of nerve growth factor to induce neuritogenesis: possible role of reactive oxygen species.
Journal of neuroscience research 2010;88(16):3644-55.
2009: Usha Gundimeda; Jason Eric Schiffman; Simcha Neeli Gottlieb; Brandon Ian Roth; Rayudu Gopalakrishna
Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase.
Carcinogenesis 2009;30(9):1553-61.
2008: Usha Gundimeda; Jason Eric Schiffman; Divya Chhabra; Jourdan Wong; Adela Wu; Rayudu Gopalakrishna
Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells.
The Journal of biological chemistry 2008;283(50):34519-31.
2008: Rayudu Gopalakrishna; Usha Gundimeda; Jason Eric Schiffman; Thomas H McNeill
A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells.
The Journal of biological chemistry 2008;283(21):14430-44.
2005: Myriam Cordey; Usha Gundimeda; Rayudu Gopalakrishna; Christian J Pike
The synthetic estrogen 4-estren-3 alpha,17 beta-diol (estren) induces estrogen-like neuroprotection.
Neurobiology of disease 2005;19(1-2):331-9.
2003: Myriam Cordey; Usha Gundimeda; Rayudu Gopalakrishna; Christian J Pike
Estrogen activates protein kinase C in neurons: role in neuroprotection.
Journal of neurochemistry 2003;84(6):1340-8.
2002: Rayudu Gopalakrishna; Usha Gundimeda
Antioxidant regulation of protein kinase C in cancer prevention.
The Journal of nutrition 2002;132(12):3819S-3823S.
2001: H Qiao; Taiji Sakamoto; D R Hinton; Rayudu Gopalakrishna; Tatsuro Ishibashi; Stephen J Ryan; Hajime Inomata
Interferon beta affects retinal pigment epithelial cell proliferation via protein kinase C pathways.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde 2001;215(6):401-7.
2001: Rayudu Gopalakrishna; Usha Gundimeda
Protein kinase C as a molecular target for cancer prevention by selenocompounds.
Nutrition and cancer 2001;40(1):55-63.
2000: Rayudu Gopalakrishna; S Jaken
Protein kinase C signaling and oxidative stress.
Free radical biology & medicine 2000;28(9):1349-61.
1999: Rayudu Gopalakrishna; Usha Gundimeda; W B Anderson; N H Colburn; Thomas Slaga
Tumor promoter benzoyl peroxide induces sulfhydryl oxidation in protein kinase C: its reversibility is related to the cellular resistance to peroxide-induced cytotoxicity.
Archives of biochemistry and biophysics 1999;363(2):246-58.
1999: Rayudu Gopalakrishna; Usha Gundimeda; Joseph A Fontana; Robert Clarke
Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status.
Cancer letters 1999;136(2):143-51.
1998: S Hoffman; Rayudu Gopalakrishna; Usha Gundimeda; T Murata; Christine Spee; Stephen J Ryan; David R Hinton
Verapamil inhibits proliferation, migration and protein kinase C activity in human retinal pigment epithelial cells.
Experimental eye research 1998;67(1):45-52.
1998: N Kaul; Rayudu Gopalakrishna; Usha Gundimeda; Jongkyu Choi; Henry Jay Forman
Role of protein kinase C in basal and hydrogen peroxide-stimulated NF-kappa B activation in the murine macrophage J774A.1 cell line.
Archives of biochemistry and biophysics 1998;350(1):79-86.
1997: Rayudu Gopalakrishna; Z H Chen; Usha Gundimeda
Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione: its role in inhibition of tumor promotion.
Archives of biochemistry and biophysics 1997;348(1):37-48.
1997: Rayudu Gopalakrishna; Usha Gundimeda; Z H Chen
Cancer-preventive selenocompounds induce a specific redox modification of cysteine-rich regions in Ca(2+)-dependent isoenzymes of protein kinase C.
Archives of biochemistry and biophysics 1997;348(1):25-36.
1997: H Kimura; M S Harris; Taiji Sakamoto; Rayudu Gopalakrishna; Usha Gundimeda; Jing Z Cui; Christine Spee; David R Hinton; Stephen J Ryan
Hypericin inhibits choroidal endothelial cell proliferation and cord formation in vitro.
Current eye research 1997;16(10):967-72.
1996: H B Hamilton; David R Hinton; Ronald E Law; Rayudu Gopalakrishna; Y Z Su; Z H Chen; Martin H Weiss; W T Couldwell
Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic application.
Journal of neurosurgery 1996;85(2):329-34.
1996: Usha Gundimeda; Z H Chen; Rayudu Gopalakrishna
Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells.
The Journal of biological chemistry 1996;271(23):13504-14.
1996: W Zhang; L Anker; Ronald E Law; David R Hinton; Rayudu Gopalakrishna; Q Pu; Usha Gundimeda; Martin H Weiss; W T Couldwell
Enhancement of radiosensitivity in human malignant glioma cells by hypericin in vitro.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(5):843-6.
1996: Taiji Sakamoto; David R Hinton; H Kimura; Christine Spee; Rayudu Gopalakrishna; Stephen J Ryan
Vitamin E succinate inhibits proliferation and migration of retinal pigment epithelial cells in vitro: therapeutic implication for proliferative vitreoretinopathy.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234(3):186-92.
1996: M S Harris; Taiji Sakamoto; H Kimura; S He; Christine Spee; Rayudu Gopalakrishna; Usha Gundimeda; J S Yoo; David R Hinton; Stephen J Ryan
Hypericin inhibits cell growth and induces apoptosis in retinal pigment epithelial cells: possible involvement of protein kinase C.
Current eye research 1996;15(3):255-62.
1996: B D Sippy; Florence M Hofman; A D Wright; J L Wang; Rayudu Gopalakrishna; Usha Gundimeda; S He; Stephen J Ryan; David R Hinton
Induction of intercellular adhesion molecule-1 by tumor necrosis factor-alpha through the 55-kDa receptor is dependent on protein kinase C in human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 1996;37(4):597-606.
1996: W T Couldwell; Ronald E Law; David R Hinton; Rayudu Gopalakrishna; V W Yong; Martin H Weiss
Protein kinase C and growth regulation of pituitary adenomas.
Acta neurochirurgica. Supplement 1996;65():22-6.
1995: L L Sweetman; N Y Zhang; H Peterson; Rayudu Gopalakrishna; Alex Sevanian
Effect of linoleic acid hydroperoxide on endothelial cell calcium homeostasis and phospholipid hydrolysis.
Archives of biochemistry and biophysics 1995;323(1):97-107.
1995: T L Murphy; Taiji Sakamoto; David R Hinton; Christine Spee; Usha Gundimeda; D Soriano; Rayudu Gopalakrishna; Stephen J Ryan
Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C.
Experimental eye research 1995;60(6):683-95.
1995: Taiji Sakamoto; David R Hinton; H Sakamoto; Rayudu Gopalakrishna; Stephen J Ryan; Peter J McDonnell
Thrombin induced cytoskeletal change in cultured bovine corneal endothelial cells mediated via protein kinase C pathway.
Current eye research 1995;14(1):35-45.
1995: Rayudu Gopalakrishna; Z H Chen; Usha Gundimeda
Modifications of cysteine-rich regions in protein kinase C induced by oxidant tumor promoters and enzyme-specific inhibitors.
Methods in enzymology 1995;252():132-46.
1994: Rayudu Gopalakrishna; Z H Chen; Usha Gundimeda
Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):12233-7.
1994: S J Sheu; Taiji Sakamoto; R Osusky; H M Wang; T E Ogden; Stephen J Ryan; David R Hinton; Rayudu Gopalakrishna
Transforming growth factor-beta regulates human retinal pigment epithelial cell phagocytosis by influencing a protein kinase C-dependent pathway.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1994;232(11):695-701.
1994: W T Couldwell; Rayudu Gopalakrishna; David R Hinton; S He; Martin H Weiss; Ronald E Law; Michael L J Apuzzo; R E Law
Hypericin: a potential antiglioma therapy.
Neurosurgery 1994;35(4):705-9; discussion 709-10.
1993: Rayudu Gopalakrishna; Z H Chen; Usha Gundimeda
Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding.
The Journal of biological chemistry 1993;268(36):27180-5.
1993: Rayudu Gopalakrishna; Usha Gundimeda; J C Wilson; Z H Chen
Multiwell filtration assay for rapid determination of protein phosphatase activity.
Analytical biochemistry 1993;212(1):296-9.
1993: Usha Gundimeda; S K Hara; W B Anderson; Rayudu Gopalakrishna
Retinoids inhibit the oxidative modification of protein kinase C induced by oxidant tumor promoters.
Archives of biochemistry and biophysics 1993;300(1):526-30.
1992: Rayudu Gopalakrishna; Z H Chen; Usha Gundimeda
Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C.
Biochemical and biophysical research communications 1992;189(2):950-7.
1992: Rayudu Gopalakrishna; Z H Chen; Usha Gundimeda
Irreversible oxidative inactivation of protein kinase C by photosensitive inhibitor calphostin C.
FEBS letters 1992;314(2):149-54.
1992: Rayudu Gopalakrishna; Z H Chen; Usha Gundimeda; J C Wilson; W B Anderson
Rapid filtration assays for protein kinase C activity and phorbol ester binding using multiwell plates with fitted filtration discs.
Analytical biochemistry 1992;206(1):24-35.
1991: Rayudu Gopalakrishna; W B Anderson
Reversible oxidative activation and inactivation of protein kinase C by the mitogen/tumor promoter periodate.
Archives of biochemistry and biophysics 1991;285(2):382-7.