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Ing Swie Goping

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R A Veldhoen; S L Banman; D R Hemmerling; R Odsen; T Simmen; A J Simmonds; D Alan Underhill; Ing Swie Goping
The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis.
Janice Kapty; Shanna Banman; Ing Swie Goping; John R Mercer
Evaluation of phosphatidylserine-binding peptides targeting apoptotic cells.
Steven G Chaulk; Richard P Fahlman; Ing Swie Goping; Oliver A Kent; Suneil K Khanna; Andrew M MacMillan; Joshua T Mendell; Gina L Thede; Richard A Veldhoen; Zhizhong Xu; Emily M Gesner; Howard S Young; J N Mark Glover
Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis.

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All Publications

2013: R A Veldhoen; S L Banman; D R Hemmerling; R Odsen; T Simmen; A J Simmonds; D Alan Underhill; Ing Swie Goping
The chemotherapeutic agent paclitaxel inhibits autophagy through two distinct mechanisms that regulate apoptosis.
Oncogene 2013;32(6):736-46.
2012: Janice Kapty; Shanna Banman; Ing Swie Goping; John R Mercer
Evaluation of phosphatidylserine-binding peptides targeting apoptotic cells.
Journal of biomolecular screening 2012;17(10):1293-301.
2011: Steven G Chaulk; Richard P Fahlman; Ing Swie Goping; Oliver A Kent; Suneil K Khanna; Andrew M MacMillan; Joshua T Mendell; Gina L Thede; Richard A Veldhoen; Zhizhong Xu; Emily M Gesner; Howard S Young; J N Mark Glover
Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis.
RNA biology 2011;8(6):1105-14.
2011: Jerome THIERY; Michael Walch; Denis Martinvalet; R Chris Bleackley; Emmanuel Boucrot; Steeve Boulant; Ing Swie Goping; Dennis Keefe; Tomas Kirchhausen; Judy Lieberman
Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.
Nature immunology 2011;12(8):770-7.
2011: Carolina S Ilkow; Ing Swie Goping; Tom C Hobman
The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax.
PLoS pathogens 2011;7(2):e1001291.
2011: Nasser Samadi; Luis M Schang; Raie T Bekele; Ing Swie Goping; David N Brindley
Lysophosphatidate induces chemo-resistance by releasing breast cancer cells from taxol-induced mitotic arrest.
PloS one 2011;6(5):e20608.
2010: A C Craik; R A Veldhoen; M Czernick; T W Buckland; K Kyselytzia; S Ghosh; Raymond Lai; Sambasivarao Damaraju; D Alan Underhill; John R Mackey; Ing Swie Goping
The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism.
Oncogene 2010;29(39):5381-91.
2010: Carolina S Ilkow; Daniel Weckbecker; Woo Jung Cho; Stephan Meier; Martin D Beatch; Ing Swie Goping; Johannes M Herrmann; Tom C Hobman
The rubella virus capsid protein inhibits mitochondrial import.
Journal of virology 2010;84(1):119-30.
2009: N Samadi; C Gaetano; Ing Swie Goping; David N Brindley
Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis.
Oncogene 2009;28(7):1028-39.
2009: Matt Czernick; Aja Rieger; Ing Swie Goping
Bim is reversibly phosphorylated but plays a limited role in paclitaxel cytotoxicity of breast cancer cell lines.
Biochemical and biophysical research communications 2009;379(1):145-50.
2008: Brenda L Duggan; Nora R Cabilio; Peter Dickie; Jennifer Witmer; Ing Swie Goping; D Alan Underhill; R Chris Bleackley
A novel lineage-specific hypersensitive site is essential for position independent granzyme B expression in transgenic mice.
Biochemical and biophysical research communications 2008;368(2):357-63.
2008: Ing Swie Goping; Tracy Sawchuk; Aja Rieger; Irene Shostak; R Chris Bleackley
Cytotoxic T lymphocytes overcome Bcl-2 inhibition: target cells contribute to their own demise.
Blood 2008;111(4):2142-51.
2006: Ing Swie Goping; Tracy Sawchuk; D Alan Underhill; R Chris Bleackley
Identification of {alpha}-tubulin as a granzyme B substrate during CTL-mediated apoptosis.
Journal of cell science 2006;119(Pt 5):858-65.
2006: Kirstin Veugelers; Bruce Motyka; Ing Swie Goping; Irene Shostak; Tracy Sawchuk; R Chris Bleackley
Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.
Molecular biology of the cell 2006;17(2):623-33.
2004: Jonathan C Choy; Vivian H Y Hung; Arwen L Hunter; Paul K Cheung; Bruce Motyka; Ing Swie Goping; Tracy Sawchuk; R Chris Bleackley; Thomas J Podor; Bruce M McManus; David J Granville
Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2245-50.
2003: Darren L Roberts; Ing Swie Goping; R Chris Bleackley
Mitochondria at the heart of the cytotoxic attack.
Biochemical and biophysical research communications 2003;304(3):513-8.
2003: Ing Swie Goping; Michele Barry; Peter Liston; Tracy Sawchuk; Gabriela Constantinescu; Karolina M Michalak; Irene Shostak; Darren L Roberts; Allison M Hunter; Robert G Korneluk; R Chris Bleackley
Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition.
Immunity 2003;18(3):355-65.
2000: JA Heibein; Ing Swie Goping; Michele Barry; Michael J Pinkoski; Gordon C Shore; Douglas R Green; R Chris Bleackley
Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.
The Journal of experimental medicine 2000;192(10):1391-402.
2000: S C Ruffolo; David G Breckenridge; Mai Nguyen; Ing Swie Goping; A Gross; S J Korsmeyer; H Li; J Yuan; Gordon C Shore
BID-dependent and BID-independent pathways for BAX insertion into mitochondria.
Cell death and differentiation 2000;7(11):1101-8.
2000: Kimitoshi Nakamura; Ella Bossy-Wetzel; K Burns; Marc P Fadel; M Lozyk; Ing Swie Goping; Michal Opas; R Chris Bleackley; Douglas R Green; Marek Michalak
Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis.
The Journal of cell biology 2000;150(4):731-40.
1998: Ing Swie Goping; A Gross; Josée N Lavoie; Mai Nguyen; R Jemmerson; K Roth; S J Korsmeyer; Gordon C Shore
Regulated targeting of BAX to mitochondria.
The Journal of cell biology 1998;143(1):207-15.
1997: E Schleiff; Gordon C Shore; Ing Swie Goping
Interactions of the human mitochondrial protein import receptor, hTom20, with precursor proteins in vitro reveal pleiotropic specificities and different receptor domain requirements.
The Journal of biological chemistry 1997;272(28):17784-9.
1997: E Schleiff; Gordon C Shore; Ing Swie Goping
Human mitochondrial import receptor, Tom20p. Use of glutathione to reveal specific interactions between Tom20-glutathione S-transferase and mitochondrial precursor proteins.
FEBS letters 1997;404(2-3):314-8.
1996: Heidi McBride; Ing Swie Goping; Gordon C Shore
The human mitochondrial import receptor, hTom20p, prevents a cryptic matrix targeting sequence from gaining access to the protein translocation machinery.
The Journal of cell biology 1996;134(2):307-13.
1995: Ing Swie Goping; D G Millar; Gordon C Shore
Identification of the human mitochondrial protein import receptor, huMas20p. Complementation of delta mas20 in yeast.
FEBS letters 1995;373(1):45-50.
1995: Ing Swie Goping; S Lamontagne; Gordon C Shore; Mai Nguyen
A gene-type-specific enhancer regulates the carbamyl phosphate synthetase I promoter by cooperating with the proximal GAG activating element.
Nucleic acids research 1995;23(10):1717-21.
1994: Ing Swie Goping; Gordon C Shore
Interactions between repressor and anti-repressor elements in the carbamyl phosphate synthetase I promoter.
The Journal of biological chemistry 1994;269(5):3891-6.
1992: Ing Swie Goping; Monique Lagace; Gordon C Shore
Factors interacting with the rat carbamyl phosphate synthetase promoter in expressing and nonexpressing tissues.
Gene 1992;118(2):283-7.
1992: Monique Lagace; Ing Swie Goping; C R Mueller; M Lazzaro; Gordon C Shore
The carbamyl phosphate synthetase promoter contains multiple binding sites for C/EBP-related proteins.
Gene 1992;118(2):231-8.