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Siamon Gordon

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Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Claudine Neyen; Annette Plüddemann; Maud Bossard; Siamon Gordon; Eleni Maniati; Subhankar Mukhopadhyay; Thorsten Hagemann
Macrophage scavenger receptor a promotes tumor progression in murine models of ovarian and pancreatic cancer.
Fernando O Martinez; Barbro N Melgert; Ronny Milde; Nick H Ten Hacken; Benjamin Thomas; Audrey Varin; Viviana Cobos Jiménez; Anjali Crawshaw; Christina Draijer; Marco Fabbri; David R Greaves; Jörg Hamann; Laura Helming; Ling-Pei Ho; Neeltje A Kootstra; Massimo Locati; Alberto Mantovani; Siamon Gordon
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.

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All Publications

2013: Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Immunity 2013;38(4):729-41.
2013: Claudine Neyen; Annette Plüddemann; Maud Bossard; Siamon Gordon; Eleni Maniati; Subhankar Mukhopadhyay; Thorsten Hagemann
Macrophage scavenger receptor a promotes tumor progression in murine models of ovarian and pancreatic cancer.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(7):3798-805.
2013: Fernando O Martinez; Barbro N Melgert; Ronny Milde; Nick H Ten Hacken; Benjamin Thomas; Audrey Varin; Viviana Cobos Jiménez; Anjali Crawshaw; Christina Draijer; Marco Fabbri; David R Greaves; Jörg Hamann; Laura Helming; Ling-Pei Ho; Neeltje A Kootstra; Massimo Locati; Alberto Mantovani; Siamon Gordon
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.
Blood 2013;121(9):e57-69.
2013: Dawn Me Bowdish; Siamon Gordon; Adrian Vs Hill; Philip C Hill; Nathan A Lack; Melanie J Newport; Kaori Sakamoto; Giorgio Sirugo; Fredrik O Vannberg
Genetic variants of MARCO are associated with susceptibility to pulmonary tuberculosis in a Gambian population.
BMC medical genetics 2013;14():47.
2012: Marietta Herrmann; Jörg Bornemann; Andrea Büscher; Siamon Gordon; Steffen Gräber; Alexander Heiss; Laura Helming; Martin Herrmann; Anne Kinkeldey; Falk Nimmerjahn; Cora Schäfer; Martin M N Schmitt; Willi Jahnen-Dechent
Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A.
Circulation research 2012;111(5):575-84.
2012: Siamon Gordon
Targeting a monocyte subset to reduce inflammation.
Circulation research 2012;110(12):1546-8.
2012: Siamon Gordon
Macrophage heterogeneity: a personal scientific journey.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(6):1339-42.
2012: Julia Kzhyshkowska; Claudine Neyen; Siamon Gordon
Role of macrophage scavenger receptors in atherosclerosis.
Immunobiology 2012;217(5):492-502.
2012: Yi-Shu Huang; Martin Stacey; Wen-Pin Tsai; Simon Yona; Gin-Wen Chang; Kai-Fong Cheng; Nien-Yi Chiang; Siamon Gordon; Cheng-Chih Hsiao; Ching-Hsun Hu; Hsi-Hsien Lin
Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains.
Molecular and cellular biology 2012;32(8):1408-20.
2012: Luisa Martinez-Pomares; Siamon Gordon
CD169+ macrophages at the crossroads of antigen presentation.
Trends in immunology 2012;33(2):66-70.
2012: Siamon Gordon
Innate immune functions of macrophages in different tissue environments.
Journal of innate immunity 2012;4(5-6):409-10.
2012: Sigrid Em Heinsbroek; Anneke Oei; Joris J T H Roelofs; Anje te Velde; Shobhit Dhawan; Siamon Gordon; Wouter J de Jonge
Genetic deletion of dectin-1 does not affect the course of murine experimental colitis.
BMC gastroenterology 2012;12():33.
2011: Ruslan Medzhitov; Andrew L Mellor; David H Munn; Chen Dong; Leona Gabryšová; Dmitry Gabrilovich; Siamon Gordon; Göran K Hansson; Ashleigh Howes; Peter Libby; Ethan M Shevach; Ken Shortman; Giorgio Trinchieri; Anne O'Garra
Highlights of 10 years of immunology in Nature Reviews Immunology.
Nature reviews. Immunology 2011;11(10):693-702.
2011: Siamon Gordon; Jörg Hamann; Hsi-Hsien Lin; Martin Stacey
F4/80 and the related adhesion-GPCRs.
European journal of immunology 2011;41(9):2472-6.
2011: Siamon Gordon; Alberto Mantovani
Diversity and plasticity of mononuclear phagocytes.
European journal of immunology 2011;41(9):2470-2.
2011: Soraya Zorro Manrique; Noweeda Mirza; Joan Stein-Streilein; Maria Adelaida Duque Correa; Ana Lucia Dominguez; Siamon Gordon; Dominique Hoelzinger; Hsi-Hsien Lin; Joseph Lustgarten
Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth.
The Journal of experimental medicine 2011;208(7):1485-99.
2011: Rosalind E Seeds; Subhankar Mukhopadhyay; Ian M Jones; Siamon Gordon; Joanna L Miller
The role of myeloid receptors on murine plasmacytoid dendritic cells in induction of type I interferon.
International immunopharmacology 2011;11(7):794-801.
2011: Annette Plüddemann; Subhankar Mukhopadhyay; Siamon Gordon
Innate immunity to intracellular pathogens: macrophage receptors and responses to microbial entry.
Immunological reviews 2011;240(1):11-24.
2011: John Q Davies; Hsi-Hsien Lin; Martin Stacey; Simon Yona; Gin-Wen Chang; Siamon Gordon; Jörg Hamann; Leticia Campo; Cheng Han; Peter Chan; Stephen B Fox
Leukocyte adhesion-GPCR EMR2 is aberrantly expressed in human breast carcinomas and is associated with patient survival.
Oncology reports 2011;25(3):619-27.
2011: Subhankar Mukhopadhyay; Audrey Varin; Yunying Chen; Baoying Liu; Karl Tryggvason; Siamon Gordon
SR-A/MARCO-mediated ligand delivery enhances intracellular TLR and NLR function, but ligand scavenging from cell surface limits TLR4 response to pathogens.
Blood 2011;117(4):1319-28.
2011: Claudine Neyen; Annette Pluddemann; Siamon Gordon
Identification of scavenger receptor ligands.
Methods in molecular biology (Clifton, N.J.) 2011;748():35-50.
2010: Subhankar Mukhopadhyay; Annette Plüddemann; Claire Hoe; Kevin J Williams; Audrey Varin; Katherine Makepeace; Marie-Laure Aknin; Dawn M E Bowdish; Stephen T Smale; A Neil Barclay; Siamon Gordon
Immune inhibitory ligand CD200 induction by TLRs and NLRs limits macrophage activation to protect the host from meningococcal septicemia.
Cell host & microbe 2010;8(3):236-47.
2010: Marcela Rosas; Benjamin Thomas; Martin Stacey; Siamon Gordon; Philip R Taylor
The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B.
Journal of leukocyte biology 2010;88(1):169-80.
2010: Nathalie Court; Virginie Vasseur; Rachel Vacher; Cécile Frémond; Yury Shebzukhov; Vladimir V Yeremeev; Isabelle Maillet; Sergei A Nedospasov; Siamon Gordon; Padraic G Fallon; Hiroshi Suzuki; Bernhard RYFFEL; Valerie QUESNIAUX
Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):7057-70.
2010: Frédéric Geissmann; Siamon Gordon; David A Hume; Allan M Mowat; Gwendalyn J Randolph
Unravelling mononuclear phagocyte heterogeneity.
Nature reviews. Immunology 2010;10(6):453-60.
2010: Siamon Gordon; Fernando O Martinez
Alternative activation of macrophages: mechanism and functions.
Immunity 2010;32(5):593-604.
2010: Konstantia-Maria Chavele; Luisa Martinez-Pomares; Jan Domin; Samantha Pemberton; Stuart M Haslam; Anne Dell; H Terence Cook; Charles D Pusey; Siamon Gordon; Alan D Salama
Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice.
The Journal of clinical investigation 2010;120(5):1469-78.
2010: Santiago Gonzalez; Veronika Lukacs-Kornek; Michael P Kuligowski; Lisa A Pitcher; Søren E Degn; Young-A Kim; Mary J Cloninger; Luisa Martinez-Pomares; Siamon Gordon; Shannon Turley; Michael C Carroll
Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes.
Nature immunology 2010;11(5):427-34.
2010: Rajinder P Parti; Robyn Loper; Gordon D Brown; Siamon Gordon; Philip R Taylor; Joseph V Bonventre; Robert C Murphy; David L Williams; Christina C Leslie
Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1.
American journal of respiratory cell and molecular biology 2010;42(4):415-23.
2010: Audrey Varin; Subhankar Mukhopadhyay; Georges Herbein; Siamon Gordon
Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion.
Blood 2010;115(2):353-62.
2010: Hsi-Hsien Lin; Martin Stacey; Joan Stein-Streilein; Siamon Gordon
F4/80: the macrophage-specific adhesion-GPCR and its role in immunoregulation.
Advances in experimental medicine and biology 2010;706():149-56.
2009: Claudine Neyen; Annette Plüddemann; Pietro Roversi; Benjamin Thomas; Lei Cai; Deneys R van der Westhuyzen; Robert B Sim; Siamon Gordon
Macrophage scavenger receptor A mediates adhesion to apolipoproteins A-I and E.
Biochemistry 2009;48(50):11858-71.
2009: Rosalind E Seeds; Siamon Gordon; Joanna L Miller
Characterisation of myeloid receptor expression and interferon alpha/beta production in murine plasmacytoid dendritic cells by flow cytomtery.
Journal of immunological methods 2009;350(1-2):106-17.
2009: Laura Helming; Siamon Gordon
Molecular mediators of macrophage fusion.
Trends in cell biology 2009;19(10):514-22.
2009: Esmerij P van der Zanden; Susanne A Snoek; Sigrid E Heinsbroek; Oana I Stanisor; Caroline Verseijden; Guy E Boeckxstaens; Maikel P Peppelenbosch; David Greaves; Siamon Gordon; Wouter J de Jonge
Vagus nerve activity augments intestinal macrophage phagocytosis via nicotinic acetylcholine receptor alpha4beta2.
Gastroenterology 2009;137(3):1029-39, 1039.e1-4.
2009: Thomas Areschoug; Siamon Gordon
Scavenger receptors: role in innate immunity and microbial pathogenesis.
Cellular microbiology 2009;11(8):1160-9.
2009: Julia Kzhyshkowska; Siamon Gordon
Vesicular trafficking in immune cells.
Immunobiology 2009;214(7):493-4.
2009: Audrey Varin; Siamon Gordon
Alternative activation of macrophages: immune function and cellular biology.
Immunobiology 2009;214(7):630-41.
2009: Dawn Bowdish; Kaori Sakamoto; Mi-Jeong Kim; Mariliis Kroos; Subhankar Mukhopadhyay; Cynthia A Leifer; Karl Tryggvason; Siamon Gordon; David G Russell
MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.
PLoS pathogens 2009;5(6):e1000474.
2009: David Greaves; Siamon Gordon
The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges.
Journal of lipid research 2009;50 Suppl():S282-6.
2009: Tammy Ozment-Skelton; Elizabeth A deFluiter; Tuanzhu Ha; Chuanfu Li; Bridget M Graves; Donald A Ferguson; John B Schweitzer; Johanna Preizsner; Gordon D Brown; Siamon Gordon; John H Kalbfleisch; David L Williams
Leukocyte Dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis.
Critical care medicine 2009;37(3):1038-45.
2009: Hidde J Haisma; Marije Boesjes; Antoine M Beerens; Barry W A van der Strate; David T Curiel; Annette Plüddemann; Siamon Gordon; Anna Rita Bellu
Scavenger receptor A: a new route for adenovirus 5.
Molecular pharmaceutics 2009;6(2):366-74.
2009: Laura Helming; Julia Winter; Siamon Gordon
The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion.
Journal of cell science 2009;122(Pt 4):453-9.
2009: Siamon Gordon; Trinchieri Giorgio
Innate resistance and inflammation.
Current opinion in immunology 2009;21(1):1-2.
2009: Annette Plüddemann; Claire Hoe; Katherine Makepeace; E Richard Moxon; Siamon Gordon
The macrophage scavenger receptor A is host-protective in experimental meningococcal septicaemia.
PLoS pathogens 2009;5(2):e1000297.
2009: Matthew deschoolmeester; Luisa Martinez-Pomares; Siamon Gordon; Kathryn J Else
The mannose receptor binds Trichuris muris excretory/secretory proteins but is not essential for protective immunity.
Immunology 2009;126(2):246-55.
2009: Sigrid E M Heinsbroek; Lynn A Kamen; Philip R Taylor; Gordon D Brown; Joel A Swanson; Siamon Gordon
Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages.
Journal of innate immunity 2009;1(3):244-53.
2009: Annette Plüddemann; Subhankar Mukhopadhyay; Marko Sankala; Silvana Savino; Mariagrazia Pizza; Rino Rappuoli; Karl Tryggvason; Siamon Gordon
SR-A, MARCO and TLRs differentially recognise selected surface proteins from Neisseria meningitidis: an example of fine specificity in microbial ligand recognition by innate immune receptors.
Journal of innate immunity 2009;1(2):153-63.
2009: Subhankar Mukhopadhyay; Annette Plüddemann; Siamon Gordon
Macrophage pattern recognition receptors in immunity, homeostasis and self tolerance.
Advances in experimental medicine and biology 2009;653():1-14.
2009: Sigrid E M Heinsbroek; Siamon Gordon
The role of macrophages in inflammatory bowel diseases.
Expert reviews in molecular medicine 2009;11():e14.
2009: Hsi-Hsien Lin; Gin-Wen Chang; Yi-Shu Huang; Cheng-Chih Hsiao; Martin Stacey; Siamon Gordon
Multivalent protein probes for the identification and characterization of cognate cellular ligands for myeloid cell surface receptors.
Methods in molecular biology (Clifton, N.J.) 2009;531():89-101.
2009: Dawn Bowdish; Siamon Gordon
Conserved domains of the class A scavenger receptors: evolution and function.
Immunological reviews 2009;227(1):19-31.
2009: Fernando O Martinez; Laura Helming; Siamon Gordon
Alternative activation of macrophages: an immunologic functional perspective.
Annual review of immunology 2009;27():451-83.
2008: Siamon Gordon
Elie Metchnikoff: father of natural immunity.
European journal of immunology 2008;38(12):3257-64.
2008: Sigrid E M Heinsbroek; Philip R Taylor; Fernando O Martinez; Luisa Martinez-Pomares; Gordon D Brown; Siamon Gordon
Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.
PLoS pathogens 2008;4(11):e1000218.
2008: Thomas Areschoug; Johan Waldemarsson; Siamon Gordon
Evasion of macrophage scavenger receptor A-mediated recognition by pathogenic streptococci.
European journal of immunology 2008;38(11):3068-79.
2008: Simon Yona; Hsi-Hsien Lin; Willie O Siu; Siamon Gordon; Martin Stacey
Adhesion-GPCRs: emerging roles for novel receptors.
Trends in biochemical sciences 2008;33(10):491-500.
2008: Elwira Pyz; Cristal Huysamen; Andrew S J Marshall; Siamon Gordon; Philip R Taylor; Gordon D Brown
Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand.
European journal of immunology 2008;38(4):1157-63.
2008: Elizabeth L Adams; Peter J Rice; Bridget Graves; Harry E Ensley; Hai Yu; Gordon D Brown; Siamon Gordon; Mario A Monteiro; Erzsebet Papp-Szabo; Douglas W Lowman; Trevor D Power; Michael F Wempe; David L Williams
Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching.
The Journal of pharmacology and experimental therapeutics 2008;325(1):115-23.
2008: Pei-Ling Chiu; Boon Han Ng; Gin-Wen Chang; Siamon Gordon; Hsi-Hsien Lin
Putative alternative trans-splicing of leukocyte adhesion-GPCR pre-mRNAs generates functional chimeric receptors.
FEBS letters 2008;582(5):792-8.
2008: Simon Yona; Hsi-Hsien Lin; Pietro Dri; John Q Davies; Richard P G Hayhoe; Sion M Lewis; Sigrid E M Heinsbroek; K Alun Brown; Mauro Perretti; Jörg Hamann; David F Treacher; Siamon Gordon; Martin Stacey
Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):741-51.
2008: Joanna L Miller; Barend J M de Wet; Barend J M deWet; Luisa Martinez-Pomares; Catherine M Radcliffe; Raymond A Dwek; Pauline M Rudd; Siamon Gordon
The mannose receptor mediates dengue virus infection of macrophages.
PLoS pathogens 2008;4(2):e17.
2008: Kevin M Dennehy; Gerben Ferwerda; Inês Faro-Trindade; Elwira Pyz; Janet A Willment; Philip R Taylor; Ann Kerrigan; S Vicky Tsoni; Siamon Gordon; Friederike Meyer-Wentrup; Gosse J Adema; Bart Jan Kullberg; Edina Schweighoffer; Victor L J Tybulewicz; Hector Mora-Montes; Neil A R Gow; David L Williams; Mihai G Netea; Gordon D Brown
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.
European journal of immunology 2008;38(2):500-6.
2008: Laura Helming; Elena Tomasello; Themis R Kyriakides; Fernando O Martinez; Toshiyuki Takai; Siamon Gordon; Eric Vivier
Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.
Science signaling 2008;1(43):ra11.
2008: Thomas Areschoug; Siamon Gordon
Pattern recognition receptors and their role in innate immunity: focus on microbial protein ligands.
Contributions to microbiology 2008;15():45-60.
2008: Luisa Martinez-Pomares; Siamon Gordon
Murine macrophages: a technical approach.
Methods in molecular biology (Clifton, N.J.) 2008;415():255-72.
2008: Annette Plüddemann; Claudine Neyen; Siamon Gordon; Leanne Peiser
A sensitive solid-phase assay for identification of class A macrophage scavenger receptor ligands using cell lysate.
Journal of immunological methods 2008;329(1-2):167-75.
2007: Luisa Martinez-Pomares; Siamon Gordon
Antigen presentation the macrophage way.
Cell 2007;131(4):641-3.
2007: Dawn Bowdish; M S Loffredo; S Mukhopadhyay; Alberto Mantovani; Siamon Gordon
Macrophage receptors implicated in the "adaptive" form of innate immunity.
Microbes and infection / Institut Pasteur 2007;9(14-15):1680-7.
2007: Siamon Gordon
The macrophage: past, present and future.
European journal of immunology 2007;37 Suppl 1():S9-17.
2007: Annette Plüddemann; Claudine Neyen; Siamon Gordon
Macrophage scavenger receptors and host-derived ligands.
Methods (San Diego, Calif.) 2007;43(3):207-17.
2007: Jörg Hamann; Nathalie Koning; Walter Pouwels; Laurien H Ulfman; Martin van Eijk; Martin Stacey; Hsi-Hsien Lin; Siamon Gordon; Mark J Kwakkenbos
EMR1, the human homolog of F4/80, is an eosinophil-specific receptor.
European journal of immunology 2007;37(10):2797-802.
2007: John Q Davies; Gin-Wen Chang; Simon Yona; Siamon Gordon; Martin Stacey; Hsi-Hsien Lin
The role of receptor oligomerization in modulating the expression and function of leukocyte adhesion-G protein-coupled receptors.
The Journal of biological chemistry 2007;282(37):27343-53.
2007: Marcela Rosas; Siamon Gordon; Philip R Taylor
Characterisation of the expression and function of the GM-CSF receptor alpha-chain in mice.
European journal of immunology 2007;37(9):2518-28.
2007: Samantha Griffiths; Neil Portman; Philip R Taylor; Siamon Gordon; Michael L Ginger; Keith Gull
RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection.
Eukaryotic cell 2007;6(7):1248-50.
2007: James Brown; Chris A O'Callaghan; Andrew S J Marshall; Robert J C Gilbert; Christian Siebold; Siamon Gordon; Gordon D Brown; E Yvonne Jones
Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.
Protein science : a publication of the Protein Society 2007;16(6):1042-52.
2007: Shlomo Nedvetzki; Stefanie Sowinski; Robert A Eagle; James Harris; Frédéric Vély; Daniela Pende; John Trowsdale; Eric Vivier; Siamon Gordon; Daniel M Davis
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.
Blood 2007;109(9):3776-85.
2007: Emma J McKenzie; Philip R Taylor; Richard J Stillion; Andrew D Lucas; James Harris; Siamon Gordon; Luisa Martinez-Pomares
Mannose receptor expression and function define a new population of murine dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):4975-83.
2007: Gin-Wen Chang; John Q Davies; Martin Stacey; Simon Yona; Dawn Bowdish; Jörg Hamann; Tse-Ching Chen; Chun-Yen Lin; Siamon Gordon; Hsi-Hsien Lin
CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells.
Biochemical and biophysical research communications 2007;353(1):133-8.
2007: Simon Yona; Siamon Gordon
Inflammation: Glucocorticoids turn the monocyte switch.
Immunology and cell biology 2007;85(2):81-2.
2007: Laura Helming; Siamon Gordon
The molecular basis of macrophage fusion.
Immunobiology 2007;212(9-10):785-93.
2007: Siamon Gordon
Macrophage heterogeneity and tissue lipids.
The Journal of clinical investigation 2007;117(1):89-93.
2007: Philip R Taylor; S Vicky Tsoni; Janet A Willment; Kevin M Dennehy; Marcela Rosas; Helen Findon; Ken Haynes; Chad Steele; Marina Botto; Siamon Gordon; Gordon D Brown
Dectin-1 is required for beta-glucan recognition and control of fungal infection.
Nature immunology 2007;8(1):31-8.
2007: Laura Helming; Siamon Gordon
Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules.
European journal of immunology 2007;37(1):33-42.
2006: Fernando O Martinez; Siamon Gordon; Massimo Locati; Alberto Mantovani
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7303-11.
2006: Leanne Peiser; Katherine Makepeace; Annette Plüddemann; Silvana Savino; Claire Hoe; Mariagrazia Pizza; Rino Rappuoli; E Richard Moxon; Siamon Gordon
Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay.
Infection and immunity 2006;74(9):5191-9.
2006: Andrew S J Marshall; Janet A Willment; Elwira Pyz; Kevin M Dennehy; Delyth M Reid; Pietro Dri; Siamon Gordon; Simon Y C Wong; Gordon D Brown
Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation.
European journal of immunology 2006;36(8):2159-69.
2006: Tammy Ozment-Skelton; Matthew P Goldman; Siamon Gordon; Gordon D Brown; David L Williams
Prolonged reduction of leukocyte membrane-associated Dectin-1 levels following beta-glucan administration.
The Journal of pharmacology and experimental therapeutics 2006;318(2):540-6.
2006: Lisa M Graham; S Vicky Tsoni; Janet A Willment; David L Williams; Philip R Taylor; Siamon Gordon; Kevin M Dennehy; Gordon D Brown
Soluble Dectin-1 as a tool to detect beta-glucans.
Journal of immunological methods 2006;314(1-2):164-9.
2006: Melania Capasso; Lindy G Durrant; Martin Stacey; Siamon Gordon; Judith M Ramage; Ian Spendlove
Costimulation via CD55 on human CD4+ T cells mediated by CD97.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1070-7.
2006: Zhidao Xia; Philip R Taylor; Rachel M Locklin; Siamon Gordon; Zhanfeng Cui; James T Triffitt
Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice.
Journal of cellular biochemistry 2006;98(4):966-80.
2006: Simon Yona; Sigrid E M Heinsbroek; Leanne Peiser; Siamon Gordon; Mauro Perretti; Roderick J Flower
Impaired phagocytic mechanism in annexin 1 null macrophages.
British journal of pharmacology 2006;148(4):469-77.
2006: Sigrid E M Heinsbroek; Philip R Taylor; Marcela Rosas; Janet A Willment; David L Williams; Siamon Gordon; Gordon D Brown
Expression of functionally different dectin-1 isoforms by murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5513-8.
2006: Luisa Martinez-Pomares; Dirk Wienke; Richard J Stillion; Emma J McKenzie; James N Arnold; James Harris; Eamon P McGreal; Robert B Sim; Clare M Isacke; Siamon Gordon
Carbohydrate-independent recognition of collagens by the macrophage mannose receptor.
European journal of immunology 2006;36(5):1074-82.
2006: Eamon P McGreal; Marcela Rosas; Gordon D Brown; Susanne Zamze; Simon Y C Wong; Siamon Gordon; Luisa Martinez-Pomares; Philip R Taylor
The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose.
Glycobiology 2006;16(5):422-30.
2006: Thorsten Hagemann; Julia Wilson; Frances Burke; Hagen Kulbe; Ninfeng Fiona Li; Annette Plüddemann; Kellie Charles; Siamon Gordon; Frances R Balkwill
Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):5023-32.
2006: Mike Becker; Alessia Cotena; Siamon Gordon; Nick Platt
Expression of the class A macrophage scavenger receptor on specific subpopulations of murine dendritic cells limits their endotoxin response.
European journal of immunology 2006;36(4):950-60.
2006: Subhankar Mukhopadhyay; Yunying Chen; Marko Sankala; Leanne Peiser; Timo Pikkarainen; Georg Kraal; Karl Tryggvason; Siamon Gordon
MARCO, an innate activation marker of macrophages, is a class A scavenger receptor for Neisseria meningitidis.
European journal of immunology 2006;36(4):940-9.
2006: Jasminka Boskovic; James N Arnold; Richard Stilion; Siamon Gordon; Robert B Sim; Angel Rivera-Calzada; Dirk Wienke; Clare M Isacke; Luisa Martinez-Pomares; Oscar Llorca
Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor.
The Journal of biological chemistry 2006;281(13):8780-7.
2006: Saritha Suram; Gordon D Brown; Moumita Ghosh; Siamon Gordon; Robyn Loper; Philip R Taylor; Shizuo Akira; Satoshi Uematsu; David L Williams; Christina C Leslie
Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor.
The Journal of biological chemistry 2006;281(9):5506-14.
2006: Angelina S Palma; Ten Feizi; Yibing Zhang; Mark S Stoll; Alexander M Lawson; Esther Díaz-Rodríguez; María Asunción Campanero-Rhodes; Júlia Costa; Siamon Gordon; Gordon D Brown; Wengang Chai
Ligands for the beta-glucan receptor, Dectin-1, assigned using "designer" microarrays of oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides.
The Journal of biological chemistry 2006;281(9):5771-9.
2006: James Harris; Nicole Schwinn; James A Mahoney; Hsi-Hsien Lin; Michael Shaw; Chris J Howard; Rosangela P da Silva; Siamon Gordon
A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles.
International journal of experimental pathology 2006;87(1):29-39.
2006: Annette Plüddemann; Subhankar Mukhopadhyay; Siamon Gordon
The interaction of macrophage receptors with bacterial ligands.
Expert reviews in molecular medicine 2006;8(28):1-25.
2006: Rosalind E Seeds; Siamon Gordon; Joanna L Miller
Receptors and ligands involved in viral induction of type I interferon production by plasmacytoid dendritic cells.
Immunobiology 2006;211(6-8):525-35.
2006: Elwira Pyz; Andrew S J Marshall; Siamon Gordon; Gordon D Brown
C-type lectin-like receptors on myeloid cells.
Annals of medicine 2006;38(4):242-51.
2005: Chad Steele; Rekha R Rapaka; Allison Metz; Shannon M Pop; David L Williams; Siamon Gordon; Jay K Kolls; Gordon D Brown
The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus.
PLoS pathogens 2005;1(4):e42.
2005: Siamon Gordon; Philip R Taylor
Monocyte and macrophage heterogeneity.
Nature reviews. Immunology 2005;5(12):953-64.
2005: Rita Szabó; Leanne Peiser; Annette Plüddemann; Szilvia Bösze; Sigrid Heinsbroek; Siamon Gordon; Ferenc Hudecz
Uptake of branched polypeptides with poly[L-lys] backbone by bone-marrow culture-derived murine macrophages: the role of the class a scavenger receptor.
Bioconjugate chemistry 2005;16(6):1442-50.
2005: Luisa Martinez-Pomares; Leif G Hanitsch; Richard J Stillion; Satish Keshav; Siamon Gordon
Expression of mannose receptor and ligands for its cysteine-rich domain in venous sinuses of human spleen.
Laboratory investigation; a journal of technical methods and pathology 2005;85(10):1238-49.
2005: Yunpeng Su; Talitha Bakker; James Harris; Clarence Tsang; Gordon D Brown; Mark R Wormald; Siamon Gordon; Raymond A Dwek; Pauline M Rudd; Luisa Martinez-Pomares
Glycosylation influences the lectin activities of the macrophage mannose receptor.
The Journal of biological chemistry 2005;280(38):32811-20.
2005: Peter J Rice; Elizabeth L Adams; Tammy Ozment-Skelton; Andres J Gonzalez; Matthew P Goldman; Brent E Lockhart; Luke A Barker; Kevin F Breuel; Warren K Deponti; John H Kalbfleisch; Harry E Ensley; Gordon D Brown; Siamon Gordon; David L Williams
Oral delivery and gastrointestinal absorption of soluble glucans stimulate increased resistance to infectious challenge.
The Journal of pharmacology and experimental therapeutics 2005;314(3):1079-86.
2005: Philip R Taylor; Delyth M Reid; Sigrid E M Heinsbroek; Gordon D Brown; Siamon Gordon; Simon Y C Wong
Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo.
European journal of immunology 2005;35(7):2163-74.
2005: Sigrid E M Heinsbroek; Gordon D Brown; Siamon Gordon
Dectin-1 escape by fungal dimorphism.
Trends in immunology 2005;26(7):352-4.
2005: Chung-Yan Cheung; Leo Poon; Iris H Y Ng; Winsie Luk; Sin-Fun Sia; Mavis H S Wu; Kwok-Hung Chan; Kwok-Yung Yuen; Siamon Gordon; Yi Guan; J S M Peiris
Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis.
Journal of virology 2005;79(12):7819-26.
2005: Sheena A Linehan; Roberta Weber; Scott McKercher; Ruth M Ripley; Siamon Gordon; Paul Martin
Enhanced expression of the mannose receptor by endothelial cells of the liver and spleen microvascular beds in the macrophage-deficient PU.1 null mouse.
Histochemistry and cell biology 2005;123(4-5):365-76.
2005: Hsi-Hsien Lin; Douglas E Faunce; Martin Stacey; Ania Terajewicz; Takahiko Nakamura; Jie Zhang-Hoover; Marilyn K Kerley; Michael L Mucenski; Siamon Gordon; Joan Stein-Streilein
The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance.
The Journal of experimental medicine 2005;201(10):1615-25.
2005: Hsi-Hsien Lin; Martin Stacey; Gin-Wen Chang; John Q Davies; Siamon Gordon
Method for selecting and enriching cells expressing low affinity ligands for cell surface receptors.
BioTechniques 2005;38(5):696, 698.
2005: Janet A Willment; Andrew S J Marshall; Delyth M Reid; David L Williams; Simon Y C Wong; Siamon Gordon; Gordon D Brown
The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells.
European journal of immunology 2005;35(5):1539-47.
2005: Neil C Rogers; Emma C Slack; Alexander D Edwards; Martijn A Nolte; Oliver Schulz; Edina Schweighoffer; David L Williams; Siamon Gordon; Victor L J Tybulewicz; Gordon D Brown; Caetano Reis e Sousa
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins.
Immunity 2005;22(4):507-17.
2005: Gordon D Brown; Siamon Gordon
Immune recognition of fungal beta-glucans.
Cellular microbiology 2005;7(4):471-9.
2005: Hiroyuki Yoshitomi; Noriko Sakaguchi; Katsuya Kobayashi; Gordon D Brown; Tomoyuki Tagami; Toshiko Sakihama; Keiji Hirota; Satoshi Tanaka; Takashi Nomura; Ichiro Miki; Siamon Gordon; Shizuo Akira; Takashi Nakamura; Shimon Sakaguchi
A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice.
The Journal of experimental medicine 2005;201(6):949-60.
2005: Philip R Taylor; Siamon Gordon; Luisa Martinez-Pomares
The mannose receptor: linking homeostasis and immunity through sugar recognition.
Trends in immunology 2005;26(2):104-10.
2005: Eamon P McGreal; Joanna L Miller; Siamon Gordon
Ligand recognition by antigen-presenting cell C-type lectin receptors.
Current opinion in immunology 2005;17(1):18-24.
2005: Yunpeng Roc Su; Clarence Tsang; Talitha Bakker; James Harris; Siamon Gordon; Raymond A Dwek; Luisa Martinez-Pomares; Pauline M Rudd
Glycosylation influences the ligand binding activities of mannose receptor.
Advances in experimental medicine and biology 2005;564():25-6.
2005: David Greaves; Siamon Gordon
Thematic review series: the immune system and atherogenesis. Recent insights into the biology of macrophage scavenger receptors.
Journal of lipid research 2005;46(1):11-20.
2005: Mark J Kwakkenbos; Walter Pouwels; Mourad Matmati; Martin Stacey; Hsi-Hsien Lin; Siamon Gordon; René A W van Lier; Jörg Hamann
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells.
Journal of leukocyte biology 2005;77(1):112-9.
2005: John Q Davies; Siamon Gordon
Isolation and culture of human macrophages.
Methods in molecular biology (Clifton, N.J.) 2005;290():105-16.
2005: John Q Davies; Siamon Gordon
Isolation and culture of murine macrophages.
Methods in molecular biology (Clifton, N.J.) 2005;290():91-103.
2004: Jurgen Herre; Andrew S J Marshall; Emmanuelle Caron; Alexander D Edwards; David L Williams; Edina Schweighoffer; Victor L J Tybulewicz; Caetano Reis e Sousa; Siamon Gordon; Gordon D Brown
Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages.
Blood 2004;104(13):4038-45.
2004: Dawn O'Reilly; Mark Addley; Carmel Quinn; Alison J Macfarlane; Siamon Gordon; Andrew J McKnight; David Greaves
Functional analysis of the murine Emr1 promoter identifies a novel purine-rich regulatory motif required for high-level gene expression in macrophages.
Genomics 2004;84(6):1030-40.
2004: Alessia Cotena; Siamon Gordon; Nick Platt
The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6427-32.
2004: Eamon P McGreal; Luisa Martinez-Pomares; Siamon Gordon
Divergent roles for C-type lectins expressed by cells of the innate immune system.
Molecular immunology 2004;41(11):1109-21.
2004: Subhankar Mukhopadhyay; Leanne Peiser; Siamon Gordon
Activation of murine macrophages by Neisseria meningitidis and IFN-gamma in vitro: distinct roles of class A scavenger and Toll-like pattern recognition receptors in selective modulation of surface phenotype.
Journal of leukocyte biology 2004;76(3):577-84.
2004: Subhankar Mukhopadhyay; Jurgen Herre; Gordon D Brown; Siamon Gordon
The potential for Toll-like receptors to collaborate with other innate immune receptors.
Immunology 2004;112(4):521-30.
2004: Hsi-Hsien Lin; Gin-Wen Chang; John Q Davies; Martin Stacey; James Harris; Siamon Gordon
Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif.
The Journal of biological chemistry 2004;279(30):31823-32.
2004: Delyth M Reid; Maria Montoya; Philip R Taylor; Persephone Borrow; Siamon Gordon; Gordon D Brown; Simon Y C Wong
Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions.
Journal of leukocyte biology 2004;76(1):86-94.
2004: Siamon Gordon
Pathogen recognition or homeostasis? APC receptor functions in innate immunity.
Comptes rendus biologies 2004;327(6):603-7.
2004: Natalio Garbi; Bernd Arnold; Siamon Gordon; Günter J Hämmerling; Ruth Ganss
CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):5861-9.
2004: Sanjib Bhakta; Gurdyal S Besra; Anna M Upton; Tanya Parish; Carolyn Sholto-Douglas-Vernon; Kevin J C Gibson; Stuart Knutton; Siamon Gordon; Rosangela P DaSilva; Matthew C Anderton; Edith Sim
Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target.
The Journal of experimental medicine 2004;199(9):1191-9.
2004: Andrew S J Marshall; Janet A Willment; Hsi-Hsien Lin; David L Williams; Siamon Gordon; Gordon D Brown
Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes.
The Journal of biological chemistry 2004;279(15):14792-802.
2004: Philip R Taylor; Susanne Zamze; Richard J Stillion; Simon Y C Wong; Siamon Gordon; Luisa Martinez-Pomares
Development of a specific system for targeting protein to metallophilic macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1963-8.
2004: Jurgen Herre; Siamon Gordon; Gordon D Brown
Dectin-1 and its role in the recognition of beta-glucans by macrophages.
Molecular immunology 2004;40(12):869-76.
2004: Philip R Taylor; Gordon D Brown; Jurgen Herre; David L Williams; Janet A Willment; Siamon Gordon
The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1157-62.
2004: Jurgen Herre; Janet A Willment; Siamon Gordon; Gordon D Brown
The role of Dectin-1 in antifungal immunity.
Critical reviews in immunology 2004;24(3):193-203.
2004: Subhankar Mukhopadhyay; Siamon Gordon
The role of scavenger receptors in pathogen recognition and innate immunity.
Immunobiology 2004;209(1-2):39-49.
2004: Siamon Gordon
Cancer and inflammation. Introduction.
Novartis Foundation symposium 2004;256():1-5.
2004: Andrew S J Marshall; Siamon Gordon
Commentary: C-type lectins on the macrophage cell surface--recent findings.
European journal of immunology 2004;34(1):18-24.
2004: Mark J Kwakkenbos; Else N Kop; Martin Stacey; Mourad Matmati; Siamon Gordon; Hsi-Hsien Lin; Jörg Hamann
The EGF-TM7 family: a postgenomic view.
Immunogenetics 2004;55(10):655-66.
2003: Lee-Anne Stanton; Gael Fenhalls; Andrew Lucas; Peter J Gough; David Greaves; James A Mahoney; Paul van Helden; Siamon Gordon
Immunophenotyping of macrophages in human pulmonary tuberculosis and sarcoidosis.
International journal of experimental pathology 2003;84(6):289-304.
2003: Chad Steele; Luis Marrero; Steve Swain; Allen G Harmsen; Mingquan Zheng; Gordon D Brown; Siamon Gordon; Judd E Shellito; Jay K Kolls
Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor.
The Journal of experimental medicine 2003;198(11):1677-88.
2003: Makobetsa Khati; Michael Schüman; jamal ibrahim; Quentin J Sattentau; Siamon Gordon; William James
Neutralization of infectivity of diverse R5 clinical isolates of human immunodeficiency virus type 1 by gp120-binding 2'F-RNA aptamers.
Journal of virology 2003;77(23):12692-8.
2003: Siamon Gordon
Do macrophage innate immune receptors enhance atherogenesis?
Developmental cell 2003;5(5):666-8.
2003: Janet A Willment; Hsi-Hsien Lin; Delyth M Reid; Philip R Taylor; David L Williams; Simon Y C Wong; Siamon Gordon; Gordon D Brown
Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4569-73.
2003: Martin Stacey; Gin-Wen Chang; John Q Davies; Mark J Kwakkenbos; Ralph D Sanderson; Jörg Hamann; Siamon Gordon; Hsi-Hsien Lin
The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans.
Blood 2003;102(8):2916-24.
2003: Gordon D Brown; Siamon Gordon
Fungal beta-glucans and mammalian immunity.
Immunity 2003;19(3):311-5.
2003: Sheena A Linehan; Patricia S Coulson; R Alan Wilson; Adrian P Mountford; Frank Brombacher; Luisa Martínez-Pomares; Siamon Gordon
IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni.
Laboratory investigation; a journal of technical methods and pathology 2003;83(8):1223-31.
2003: Philip R Taylor; Gordon D Brown; Anja B Geldhof; Luisa Martinez-Pomares; Siamon Gordon
Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo.
European journal of immunology 2003;33(8):2090-7.
2003: Gin-Wen Chang; Martin Stacey; Mark J Kwakkenbos; Jörg Hamann; Siamon Gordon; Hsi-Hsien Lin
Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif.
FEBS letters 2003;547(1-3):145-50.
2003: Philip R Taylor; Siamon Gordon
Monocyte heterogeneity and innate immunity.
Immunity 2003;19(1):2-4.
2003: Dawn O'Reilly; Carmel M Quinn; Tariq El-Shanawany; Siamon Gordon; David Greaves
Multiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific manner.
The Journal of biological chemistry 2003;278(24):21909-19.
2003: Gordon D Brown; Jurgen Herre; David L Williams; Janet A Willment; Andrew S J Marshall; Siamon Gordon
Dectin-1 mediates the biological effects of beta-glucans.
The Journal of experimental medicine 2003;197(9):1119-24.
2003: Luisa Martinez-Pomares; Delyth M Reid; Gordon D Brown; Philip R Taylor; Richard J Stillion; Sheena A Linehan; Susanne Zamze; Siamon Gordon; Simon Y C Wong
Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies.
Journal of leukocyte biology 2003;73(5):604-13.
2003: Siamon Gordon
Alternative activation of macrophages.
Nature reviews. Immunology 2003;3(1):23-35.
2002: Siamon Gordon
Pattern recognition receptors: doubling up for the innate immune response.
Cell 2002;111(7):927-30.
2002: Siamon Gordon
Positive about HIV--an immunological education project in South Africa.
Nature immunology 2002;3(12):1115-7.
2002: Evelyne Schaller; Alison J Macfarlane; Rudolf A Rupec; Siamon Gordon; Andrew J McKnight; Klaus Pfeffer
Inactivation of the F4/80 glycoprotein in the mouse germ line.
Molecular and cellular biology 2002;22(22):8035-43.
2002: Susanne Zamze; Luisa Martinez-Pomares; Hannah Jones; Philip R Taylor; Richard J Stillion; Siamon Gordon; Simon Y C Wong
Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor.
The Journal of biological chemistry 2002;277(44):41613-23.
2002: Philip R Taylor; Gordon D Brown; Delyth M Reid; Janet A Willment; Luisa Martinez-Pomares; Siamon Gordon; Simon Y C Wong
The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3876-82.
2002: Leanne Peiser; Menno de Winther; Katherine Makepeace; Michael Hollinshead; Philip A Coull; Joyce Plested; Tatsuhiko Kodama; E Richard Moxon; Siamon Gordon
The class A macrophage scavenger receptor is a major pattern recognition receptor for Neisseria meningitidis which is independent of lipopolysaccharide and not required for secretory responses.
Infection and immunity 2002;70(10):5346-54.
2002: Martin Stacey; Gin-Wen Chang; Stephanie L Sanos; Laura R Chittenden; Lisa Stubbs; Siamon Gordon; Hsi-Hsien Lin
EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20.
The Journal of biological chemistry 2002;277(32):29283-93.
2002: Gordon D Brown; Philip R Taylor; Delyth M Reid; Janet A Willment; David L Williams; Luisa Martinez-Pomares; Simon Y C Wong; Siamon Gordon
Dectin-1 is a major beta-glucan receptor on macrophages.
The Journal of experimental medicine 2002;196(3):407-12.
2002: David Greaves; Siamon Gordon
Macrophage-specific gene expression: current paradigms and future challenges.
International journal of hematology 2002;76(1):6-15.
2002: Philip R Taylor; Matthew C Pickering; Marie H Kosco-Vilbois; Mark J Walport; Marina Botto; Siamon Gordon; Luisa Martinez-Pomares
The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.
European journal of immunology 2002;32(7):1888-96.
2002: Ping Yu; Yang Wang; Robert K Chin; Luisa Martinez-Pomares; Siamon Gordon; Marie H Kosco-Vibois; Jason G Cyster; Yang-Xin Fu
B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5117-23.
2002: Mark J Kwakkenbos; Gin-Wen Chang; Hsi-Hsien Lin; Walter Pouwels; Esther C de Jong; René A W van Lier; Siamon Gordon; Jörg Hamann
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells.
Journal of leukocyte biology 2002;71(5):854-62.
2002: Daniel H Wreschner; Michael A McGuckin; Stefanie J Williams; Amos Baruch; Merav Yoeli; Ravit Ziv; Liron Okun; Joseph Zaretsky; Nechama I Smorodinsky; Iafa Keydar; Pavlos Neophytou; Martin Stacey; His-Hsien Lin; Siamon Gordon
Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins.
Protein science : a publication of the Protein Society 2002;11(3):698-706.
2002: S G Balch; David Greaves; Siamon Gordon; Andrew J McKnight
Organization of the mouse macrophage C-type lectin (Mcl) gene and identification of a subgroup of related lectin molecules.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2002;29(1):61-4.
2002: Leanne Peiser; Subhankar Mukhopadhyay; Siamon Gordon
Scavenger receptors in innate immunity.
Current opinion in immunology 2002;14(1):123-8.
2002: Nick Platt; Richard Haworth; Liz Darley; Siamon Gordon
The many roles of the class A macrophage scavenger receptor.
International review of cytology 2002;212():1-40.
2001: Luisa Martinez-Pomares; Sheena A Linehan; Philip R Taylor; Siamon Gordon
Binding properties of the mannose receptor.
Immunobiology 2001;204(5):527-35.
2001: Janet A Willment; Siamon Gordon; Gordon D Brown
Characterization of the human beta -glucan receptor and its alternatively spliced isoforms.
The Journal of biological chemistry 2001;276(47):43818-23.
2001: Gordon D Brown; Siamon Gordon
Immune recognition. A new receptor for beta-glucans.
Nature 2001;413(6851):36-7.
2001: Nick Platt; Siamon Gordon
Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse's tale.
The Journal of clinical investigation 2001;108(5):649-54.
2001: Peter J Gough; Siamon Gordon; David Greaves
The use of human CD68 transcriptional regulatory sequences to direct high-level expression of class A scavenger receptor in macrophages in vitro and in vivo.
Immunology 2001;103(3):351-61.
2001: Hsi-Hsien Lin; Martin Stacey; C Saxby; Vroni Knott; Yasmin Chaudhry; D Evans; Siamon Gordon; Andrew J McKnight; Penny A Handford; Susan M Lea
Molecular analysis of the epidermal growth factor-like short consensus repeat domain-mediated protein-protein interactions: dissection of the CD97-CD55 complex.
The Journal of biological chemistry 2001;276(26):24160-9.
2001: Sheena A Linehan; Luisa Martínez-Pomares; R P da Silva; Siamon Gordon
Endogenous ligands of carbohydrate recognition domains of the mannose receptor in murine macrophages, endothelial cells and secretory cells; potential relevance to inflammation and immunity.
European journal of immunology 2001;31(6):1857-66.
2001: David Greaves; T Häkkinen; Andrew D Lucas; Kate Liddiard; Emma Jones; Carmel M Quinn; J Senaratne; Fiona R Green; Kerry L Tyson; J Boyle; C Shanahan; Peter L Weissberg; Siamon Gordon; S Ylä-Hertualla
Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(6):923-9.
2001: Martin Stacey; Hsi-Hsien Lin; K L Hilyard; Siamon Gordon; Andrew J McKnight
Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils.
The Journal of biological chemistry 2001;276(22):18863-70.
2001: Siamon Gordon
Homeostasis: a scavenger receptor for haemoglobin.
Current biology : CB 2001;11(10):R399-401.
2001: David Greaves; Siamon Gordon
Immunity, atherosclerosis and cardiovascular disease.
Trends in immunology 2001;22(4):180-1.
2001: James A Mahoney; B Ntolosi; R P DaSilva; Siamon Gordon; Andrew J McKnight
Cloning and characterization of CPVL, a novel serine carboxypeptidase, from human macrophages.
Genomics 2001;72(3):243-51.
2001: Andrew D Lucas; N Chadwick; B F Warren; D P Jewell; Siamon Gordon; F Powrie; David Greaves
The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo.
The American journal of pathology 2001;158(3):855-66.
2001: Leanne Peiser; Siamon Gordon
The function of scavenger receptors expressed by macrophages and their role in the regulation of inflammation.
Microbes and infection / Institut Pasteur 2001;3(2):149-59.
2001: Makobetsa Khati; William James; Siamon Gordon
HIV-macrophage interactions at the cellular and molecular level.
Archivum immunologiae et therapiae experimentalis 2001;49(5):367-78.
2000: Hsi-Hsien Lin; Martin Stacey; Jörg Hamann; Siamon Gordon; Andrew J McKnight
Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97.
Genomics 2000;67(2):188-200.
2000: Martin Stacey; Hsi-Hsien Lin; Siamon Gordon; Andrew J McKnight
LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors.
Trends in biochemical sciences 2000;25(6):284-9.
2000: Nick Platt; H Suzuki; Tatsuhiko Kodama; Siamon Gordon
Apoptotic thymocyte clearance in scavenger receptor class A-deficient mice is apparently normal.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4861-7.
2000: Leanne Peiser; Peter J Gough; Tatsuhiko Kodama; Siamon Gordon
Macrophage class A scavenger receptor-mediated phagocytosis of Escherichia coli: role of cell heterogeneity, microbial strain, and culture conditions in vitro.
Infection and immunity 2000;68(4):1953-63.
2000: Sheena A Linehan; Luisa Martínez-Pomares; Siamon Gordon
Macrophage lectins in host defence.
Microbes and infection / Institut Pasteur 2000;2(3):279-88.
2000: Sheena A Linehan; Luisa Martinez-Pomares; Siamon Gordon
Mannose receptor and scavenger receptor: two macrophage pattern recognition receptors with diverse functions in tissue homeostasis and host defense.
Advances in experimental medicine and biology 2000;479():1-14.
1999: Carmel M Quinn; A P Wiles; T El-Shanawany; I Catchpole; T Alnadaf; M J Ford; Siamon Gordon; David Greaves
The human eukaryotic initiation factor 4AI gene (EIF4A1) contains multiple regulatory elements that direct high-level reporter gene expression in mammalian cell lines.
Genomics 1999;62(3):468-76.
1999: Luisa Martínez-Pomares; Paul R Crocker; R Da Silva; N Holmes; Cristina Colominas; Pauline Rudd; Raymond A Dwek; Siamon Gordon
Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor.
The Journal of biological chemistry 1999;274(49):35211-8.
1999: Sheena A Linehan; Luisa Martínez-Pomares; P D Stahl; Siamon Gordon
Mannose receptor and its putative ligands in normal murine lymphoid and nonlymphoid organs: In situ expression of mannose receptor by selected macrophages, endothelial cells, perivascular microglia, and mesangial cells, but not dendritic cells.
The Journal of experimental medicine 1999;189(12):1961-72.
1999: Rosangela P da Silva; Siamon Gordon
Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal protein.
The Biochemical journal 1999;338 ( Pt 3)():687-94.
1999: Peter J Gough; David Greaves; H Suzuki; T Hakkinen; M O Hiltunen; M Turunen; S Y Herttuala; Tatsuhiko Kodama; Siamon Gordon
Analysis of macrophage scavenger receptor (SR-A) expression in human aortic atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(3):461-71.
1999: Luc J van der Laan; Ed A Döpp; R Haworth; Timo Pikkarainen; Maarit Kangas; Outi Elomaa; Christine D Dijkstra; Siamon Gordon; Karl Tryggvason; Georg Kraal
Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):939-47.
1999: Nick Platt; Rosangela P da Silva; Siamon Gordon
Class A scavenger receptors and the phagocytosis of apoptotic cells.
Immunology letters 1999;65(1-2):15-9.
1999: L Martínez-Pomares; Siamon Gordon
Potential role of the mannose receptor in antigen transport.
Immunology letters 1999;65(1-2):9-13.
1999: Siamon Gordon
Macrophage-restricted molecules: role in differentiation and activation.
Immunology letters 1999;65(1-2):5-8.
1998: David Greaves; Carmel M Quinn; Michael F Seldin; Siamon Gordon
Functional comparison of the murine macrosialin and human CD68 promoters in macrophage and nonmacrophage cell lines.
Genomics 1998;54(1):165-8.
1998: Nick Platt; Rosangela P da Silva; Siamon Gordon
Class A scavenger receptors and the phagocytosis of apoptotic cells.
Biochemical Society transactions 1998;26(4):639-44.
1998: Emma Jones; Carmel M Quinn; Chee Gee See; D S Montgomery; M J Ford; K Kölble; Siamon Gordon; David Greaves
The linked human elongation initiation factor 4A1 (EIF4A1) and CD68 genes map to chromosome 17p13.
Genomics 1998;53(2):248-50.
1998: David Greaves; Peter J Gough; Siamon Gordon
Recent progress in defining the role of scavenger receptors in lipid transport, atherosclerosis and host defence.
Current opinion in lipidology 1998;9(5):425-32.
1998: Luisa Martínez-Pomares; James A Mahoney; R Káposzta; Sheena A Linehan; P D Stahl; Siamon Gordon
A functional soluble form of the murine mannose receptor is produced by macrophages in vitro and is present in mouse serum.
The Journal of biological chemistry 1998;273(36):23376-80.
1998: Siamon Gordon
The role of the macrophage in immune regulation.
Research in immunology 1998;149(7-8):685-8.
1998: Nick Platt; Rosangela P da Silva; Siamon Gordon
Recognizing death: the phagocytosis of apoptotic cells.
Trends in cell biology 1998;8(9):365-72.
1998: Nick Platt; Siamon Gordon
Scavenger receptors: diverse activities and promiscuous binding of polyanionic ligands.
Chemistry & biology 1998;5(8):R193-203.
1998: S G Balch; Andrew J McKnight; Michael F Seldin; Siamon Gordon
Cloning of a novel C-type lectin expressed by murine macrophages.
The Journal of biological chemistry 1998;273(29):18656-64.
1998: derralynn hughes; Siamon Gordon
Expression and function of the type 3 complement receptor in tissues of the developing mouse.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4543-52.
1998: W J de Villiers; Jonathan D. Smith; M Miyata; H M Dansky; E Darley; Siamon Gordon
Macrophage phenotype in mice deficient in both macrophage-colony-stimulating factor (op) and apolipoprotein E.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(4):631-40.
1998: Peter J Gough; David Greaves; Siamon Gordon
A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake.
Journal of lipid research 1998;39(3):531-43.
1998: Andrew J McKnight; Siamon Gordon
The EGF-TM7 family: unusual structures at the leukocyte surface.
Journal of leukocyte biology 1998;63(3):271-80.
1998: S Clarke; Siamon Gordon
Myeloid-specific gene expression.
Journal of leukocyte biology 1998;63(2):153-68.
1998: Andrew J McKnight; Siamon Gordon
Membrane molecules as differentiation antigens of murine macrophages.
Advances in immunology 1998;68():271-314.
1997: Andrew J McKnight; Alison J Macfarlane; Michael F Seldin; Siamon Gordon
Chromosome mapping of the Emr1 gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(12):946.
1997: S Mucklow; Siamon Gordon; Paul R Crocker
Characterization of the mouse sialoadhesin gene, Sn.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(12):934-7.
1997: R Haworth; Nick Platt; Satish Keshav; D Hughes; E Darley; H Suzuki; Y Kurihara; Tatsuhiko Kodama; Siamon Gordon
The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock.
The Journal of experimental medicine 1997;186(9):1431-9.
1997: Satish Keshav; Andrew J McKnight; R Arora; Siamon Gordon
Cloning of intestinal phospholipase A2 from intestinal epithelial RNA by differential display PCR.
Cell proliferation 1997;30(10-12):369-83.
1997: David Greaves; W Wang; Daniel J Dairaghi; MC Dieu; B Saint-Vis; K Franz-Bacon; D Rossi; Christophe Caux; Terrill McClanahan; Siamon Gordon; Albert Zlotnik; Thomas J Schall
CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.
The Journal of experimental medicine 1997;186(6):837-44.
1996: L Martínez-Pomares; Marie H Kosco-Vilbois; E Darley; P Tree; S Herren; Jean-Yves Bonnefoy; Siamon Gordon
Fc chimeric protein containing the cysteine-rich domain of the murine mannose receptor binds to macrophages from splenic marginal zone and lymph node subcapsular sinus and to germinal centers.
The Journal of experimental medicine 1996;184(5):1927-37.
1996: G Herbein; L J Montaner; Siamon Gordon
Tumor necrosis factor alpha inhibits entry of human immunodeficiency virus type 1 into primary human macrophages: a selective role for the 75-kilodalton receptor.
Journal of virology 1996;70(11):7388-97.
1996: Nick Platt; H Suzuki; Y Kurihara; T Kodama; Siamon Gordon
Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12456-60.
1996: T Kodama; Takeshi Doi; H Suzuki; K Takahashi; Y Wada; Siamon Gordon
Collagenous macrophage scavenger receptors.
Current opinion in lipidology 1996;7(5):287-91.
1996: L Martinez-Pomares; Nick Platt; Andrew J McKnight; Rosangela P da Silva; Siamon Gordon
Macrophage membrane molecules: markers of tissue differentiation and heterogeneity.
Immunobiology 1996;195(4-5):407-16.
1996: Andrew J McKnight; Siamon Gordon
EGF-TM7: a novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules.
Immunology today 1996;17(6):283-7.
1996: G Herbein; PETER ILLEI; L J Montaner; William James; Siamon Gordon
Comparison of p24 measurement by ELISA versus indicator cells for detecting residual HIV infectivity in vitro.
Journal of virological methods 1996;58(1-2):167-73.
1996: S Clarke; David Greaves; L P Chung; P Tree; Siamon Gordon
The human lysozyme promoter directs reporter gene expression to activated myelomonocytic cells in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1434-8.
1996: Rosangela P da Silva; Nick Platt; J S de Villiers; Siamon Gordon
Membrane molecules and macrophage endocytosis: scavenger receptor and macrosialin as markers of plasma-membrane and vacuolar functions.
Biochemical Society transactions 1996;24(1):220-4.
1996: Andrew J McKnight; Alison Macfarlane; P Dri; L Turley; Antony C Willis; Siamon Gordon
Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family.
The Journal of biological chemistry 1996;271(1):486-9.
1995: G Herbein; A G Doyle; L J Montaner; Siamon Gordon
Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1 beta.
Clinical and experimental immunology 1995;102(2):430-7.
1995: P B Fischer; M Collin; G B Karlsson; William James; Terry D Butters; Simon J Davis; Siamon Gordon; Raymond A Dwek; Frances M Platt
The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding.
Journal of virology 1995;69(9):5791-7.
1995: S Mucklow; A Hartnell; M G Mattei; Siamon Gordon; Paul R Crocker
Sialoadhesin (Sn) maps to mouse chromosome 2 and human chromosome 20 and is not linked to the other members of the sialoadhesin family, CD22, MAG, and CD33.
Genomics 1995;28(2):344-6.
1995: derralynn hughes; I P Fraser; Siamon Gordon
Murine macrophage scavenger receptor: in vivo expression and function as receptor for macrophage adhesion in lymphoid and non-lymphoid organs.
European journal of immunology 1995;25(2):466-73.
1995: Siamon Gordon; S Clarke; D Greaves; A Doyle
Molecular immunobiology of macrophages: recent progress.
Current opinion in immunology 1995;7(1):24-33.
1995: L J Montaner; G Herbein; Siamon Gordon
Regulation of macrophage activation and HIV replication.
Advances in experimental medicine and biology 1995;374():47-56.
1994: W J de Villiers; I P Fraser; Siamon Gordon
Cytokine and growth factor regulation of macrophage scavenger receptor expression and function.
Immunology letters 1994;43(1-2):73-9.
1994: derralynn hughes; I P Fraser; Siamon Gordon
Murine M phi scavenger receptor: adhesion function and expression.
Immunology letters 1994;43(1-2):7-14.
1994: L J Montaner; P Griffin; Siamon Gordon
Interleukin-10 inhibits initial reverse transcription of human immunodeficiency virus type 1 and mediates a virostatic latent state in primary blood-derived human macrophages in vitro.
The Journal of general virology 1994;75 ( Pt 12)():3393-400.
1994: Paul R Crocker; S Mucklow; V Bouckson; A McWilliam; A C Willis; Siamon Gordon; G Milon; Soerge Kelm; P Bradfield
Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains.
The EMBO journal 1994;13(19):4490-503.
1994: M D Bell; R Lopez-Gonzalez; L Lawson; D Hughes; I Fraser; Siamon Gordon; V Hugh Perry
Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS.
Journal of neurocytology 1994;23(10):605-13.
1994: L J Montaner; Siamon Gordon
Th2-mediated HIV1 virostatic state: macrophage-specific regulation in vitro.
Research in immunology 1994;145(8-9):583-7; discussion 587-8.
1994: Siamon Gordon; Satish Keshav; M Stein
BCG-induced granuloma formation in murine tissues.
Immunobiology 1994;191(4-5):369-77.
1994: I Fraser; A Doyle; D Hughes; Siamon Gordon
Use of surface molecules and receptors for studying macrophages and mononuclear phagocytes.
Journal of immunological methods 1994;174(1-2):95-102.
1994: W J de Villiers; I P Fraser; D A Hughes; A G Doyle; Siamon Gordon
Macrophage-colony-stimulating factor selectively enhances macrophage scavenger receptor expression and function.
The Journal of experimental medicine 1994;180(2):705-9.
1994: I P Fraser; Siamon Gordon
Murine erythroleukemia (MEL) cells bear ligands for the sialoadhesin and erythroblast receptor macrophage hemagglutinins.
European journal of cell biology 1994;64(2):217-21.
1994: M Collin; PETER ILLEI; William James; Siamon Gordon
Definition of the range and distribution of human immunodeficiency virus macrophage tropism using PCR-based infectivity measurements.
The Journal of general virology 1994;75 ( Pt 7)():1597-603.
1994: A G Doyle; G Herbein; L J Montaner; A J Minty; D Caput; Pascual Ferrara; Siamon Gordon
Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gamma.
European journal of immunology 1994;24(6):1441-5.
1994: J Hopkinson-Woolley; D Hughes; Siamon Gordon; P Martin
Macrophage recruitment during limb development and wound healing in the embryonic and foetal mouse.
Journal of cell science 1994;107 ( Pt 5)():1159-67.
1994: M Collin; Siamon Gordon
The kinetics of human immunodeficiency virus reverse transcription are slower in primary human macrophages than in a lymphoid cell line.
Virology 1994;200(1):114-20.
1994: G Herbein; Satish Keshav; M Collin; L J Montaner; Siamon Gordon
HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection.
Clinical and experimental immunology 1994;95(3):442-9.
1993: L J Lawson; V Hugh Perry; Siamon Gordon
Microglial responses to physiological change: osmotic stress elevates DNA synthesis of neurohypophyseal microglia.
Neuroscience 1993;56(4):929-38.
1993: D M Reid; V Hugh Perry; P B Andersson; Siamon Gordon
Mitosis and apoptosis of microglia in vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier.
Neuroscience 1993;56(3):529-33.
1993: L J Montaner; A G Doyle; M Collin; G Herbein; PETER ILLEI; William James; A Minty; D Caput; Pascual Ferrara; Siamon Gordon
Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro.
The Journal of experimental medicine 1993;178(2):743-7.
1993: I Fraser; D Hughes; Siamon Gordon
Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor.
Nature 1993;364(6435):343-6.
1993: V Hugh Perry; P B Andersson; Siamon Gordon
Macrophages and inflammation in the central nervous system.
Trends in neurosciences 1993;16(7):268-73.
1993: C L Holness; R P da Silva; J Fawcett; Siamon Gordon; David L Simmons
Macrosialin, a mouse macrophage-restricted glycoprotein, is a member of the lamp/lgp family.
The Journal of biological chemistry 1993;268(13):9661-6.
1993: M Collin; G Herbein; L Montaner; Siamon Gordon
PCR analysis of HIV1 infection of macrophages: virus entry is CD4-dependent.
Research in virology 1993;144(1):13-9.
1992: A S McWilliam; P Tree; Siamon Gordon
Interleukin 4 regulates induction of sialoadhesin, the macrophage sialic acid-specific receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10522-6.
1992: MK Matyszak; L J Lawson; V Hugh Perry; Siamon Gordon
Stromal macrophages of the choroid plexus situated at an interface between the brain and peripheral immune system constitutively express major histocompatibility class II antigens.
Journal of neuroimmunology 1992;40(2-3):173-81.
1992: M Stein; Satish Keshav; N Harris; Siamon Gordon
Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation.
The Journal of experimental medicine 1992;176(1):287-92.
1992: P B Andersson; V Hugh Perry; Siamon Gordon
Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system.
The Journal of experimental medicine 1992;176(1):255-9.
1992: Siamon Gordon; I Fraser; D Nath; D Hughes; S Clarke
Macrophages in tissues and in vitro.
Current opinion in immunology 1992;4(1):25-32.
1992: S Rabinowitz; H Horstmann; Siamon Gordon; G Griffiths
Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages.
The Journal of cell biology 1992;116(1):95-112.
1992: L J Lawson; V Hugh Perry; Siamon Gordon
Turnover of resident microglia in the normal adult mouse brain.
Neuroscience 1992;48(2):405-15.
1992: P B Andersson; V Hugh Perry; Siamon Gordon
The acute inflammatory response to lipopolysaccharide in CNS parenchyma differs from that in other body tissues.
Neuroscience 1992;48(1):169-86.
1992: V H Perry; Paul R Crocker; Siamon Gordon
The blood-brain barrier regulates the expression of a macrophage sialic acid-binding receptor on microglia.
Journal of cell science 1992;101 ( Pt 1)():201-7.
1992: Siamon Gordon; L Lawson; S Rabinowitz; Paul R Crocker; L Morris; V Hugh Perry
Antigen markers of macrophage differentiation in murine tissues.
Current topics in microbiology and immunology 1992;181():1-37.
1991: Satish Keshav; P Chung; G Milon; Siamon Gordon
Lysozyme is an inducible marker of macrophage activation in murine tissues as demonstrated by in situ hybridization.
The Journal of experimental medicine 1991;174(5):1049-58.
1991: S S Rabinowitz; Siamon Gordon
Macrosialin, a macrophage-restricted membrane sialoprotein differentially glycosylated in response to inflammatory stimuli.
The Journal of experimental medicine 1991;174(4):827-36.
1991: P B Andersson; V Hugh Perry; Siamon Gordon
The CNS acute inflammatory response to excitotoxic neuronal cell death.
Immunology letters 1991;30(2):177-81.
1991: L Morris; Paul R Crocker; I Fraser; M Hill; Siamon Gordon
Expression of a divalent cation-dependent erythroblast adhesion receptor by stromal macrophages from murine bone marrow.
Journal of cell science 1991;99 ( Pt 1)():141-7.
1991: M Collin; William James; Siamon Gordon
Development of techniques to analyse the formation of HIV provirus in primary human macrophages.
Research in virology 1991;142(2-3):105-12.
1991: M Stein; Siamon Gordon
Regulation of tumor necrosis factor (TNF) release by murine peritoneal macrophages: role of cell stimulation and specific phagocytic plasma membrane receptors.
European journal of immunology 1991;21(2):431-7.
1991: Paul R Crocker; L Morris; Siamon Gordon
Adhesion receptors involved in the erythroblastic island.
Blood cells 1991;17(1):83-91; discussion 91-6.
1991: V Hugh Perry; Siamon Gordon
Macrophages and the nervous system.
International review of cytology 1991;125():203-44.
1991: P B Andersson; V Hugh Perry; Siamon Gordon
The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration.
Neuroscience 1991;42(1):201-14.
1990: Satish Keshav; L P Chung; Siamon Gordon
Macrophage products in inflammation.
Diagnostic microbiology and infectious disease 1990;13(5):439-47.
1990: Philip Calder; J A Bond; David Harvey; Siamon Gordon; Eric A Newsholme
Uptake and incorporation of saturated and unsaturated fatty acids into macrophage lipids and their effect upon macrophage adhesion and phagocytosis.
The Biochemical journal 1990;269(3):807-14.
1990: H Teppler; S H Lee; E P Rieber; Siamon Gordon
Murine immunoglobulin G anti-CD4 monoclonal antibodies bind to primary human monocytes and macrophages through Fc receptors as well as authentic CD4.
AIDS (London, England) 1990;4(7):627-32.
1990: H Rosen; Siamon Gordon
The role of the type 3 complement receptor in the induced recruitment of myelomonocytic cells to inflammatory sites in the mouse.
American journal of respiratory cell and molecular biology 1990;3(1):3-10.
1990: H Rosen; Siamon Gordon
Adoptive transfer of fluorescence-labeled cells shows that resident peritoneal macrophages are able to migrate into specialized lymphoid organs and inflammatory sites in the mouse.
European journal of immunology 1990;20(6):1251-8.
1990: Satish Keshav; L Lawson; L P Chung; M Stein; V Hugh Perry; Siamon Gordon
Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization.
The Journal of experimental medicine 1990;171(1):327-32.
1990: L J Lawson; V Hugh Perry; P Dri; Siamon Gordon
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain.
Neuroscience 1990;39(1):151-70.
1989: S Rabinowitz; Siamon Gordon
Differential expression of membrane sialoglycoproteins in exudate and resident mouse peritoneal macrophages.
Journal of cell science 1989;93 ( Pt 4)():623-30.
1989: H Rosen; Siamon Gordon
Current status review: adhesion molecules and myelomonocytic cell-endothelial interactions.
British journal of experimental pathology 1989;70(3):385-94.
1989: Paul R Crocker; Siamon Gordon
Mouse macrophage hemagglutinin (sheep erythrocyte receptor) with specificity for sialylated glycoconjugates characterized by a monoclonal antibody.
The Journal of experimental medicine 1989;169(4):1333-46.
1989: H Rosen; G Milon; Siamon Gordon
Antibody to the murine type 3 complement receptor inhibits T lymphocyte-dependent recruitment of myelomonocytic cells in vivo.
The Journal of experimental medicine 1989;169(2):535-48.
1989: D V Pow; V Hugh Perry; John F Morris; Siamon Gordon
Microglia in the neurohypophysis associate with and endocytose terminal portions of neurosecretory neurons.
Neuroscience 1989;33(3):567-78.
1988: Paul R Crocker; M Hill; Siamon Gordon
Regulation of a murine macrophage haemagglutinin (sheep erythrocyte receptor) by a species-restricted serum factor.
Immunology 1988;65(4):515-22.
1988: Jean Ripoche; J A Mitchell; A Erdei; C Madin; B Moffatt; T Mokoena; Siamon Gordon; Robert B Sim
Interferon gamma induces synthesis of complement alternative pathway proteins by human endothelial cells in culture.
The Journal of experimental medicine 1988;168(5):1917-22.
1988: L P Chung; Satish Keshav; Siamon Gordon
Cloning the human lysozyme cDNA: inverted Alu repeat in the mRNA and in situ hybridization for macrophages and Paneth cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6227-31.
1988: Siamon Gordon; Satish Keshav; L P Chung
Mononuclear phagocytes: tissue distribution and functional heterogeneity.
Current opinion in immunology 1988;1(1):26-35.
1988: S H Lee; Paul R Crocker; S Westaby; N Key; David Y Mason; Siamon Gordon; D J Weatherall
Isolation and immunocytochemical characterization of human bone marrow stromal macrophages in hemopoietic clusters.
The Journal of experimental medicine 1988;168(3):1193-8.
1988: L Morris; Paul R Crocker; Siamon Gordon
Murine fetal liver macrophages bind developing erythroblasts by a divalent cation-dependent hemagglutinin.
The Journal of cell biology 1988;106(3):649-56.
1988: Paul R Crocker; L Morris; Siamon Gordon
Novel cell surface adhesion receptors involved in interactions between stromal macrophages and haematopoietic cells.
Journal of cell science. Supplement 1988;9():185-206.
1988: Siamon Gordon; V H Perry; S Rabinowitz; L P Chung; H Rosen
Plasma membrane receptors of the mononuclear phagocyte system.
Journal of cell science. Supplement 1988;9():1-26.
1987: H Rosen; Siamon Gordon
Surface events in polymorphonuclear leucocyte activation: insights from a hydrophobic membrane antigen that triggers the respiratory burst.
Journal of cell science 1987;88 ( Pt 5)():591-601.
1987: H Rosen; Siamon Gordon
Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.
The Journal of experimental medicine 1987;166(6):1685-701.
1987: V Hugh Perry; Siamon Gordon
Modulation of CD4 antigen on macrophages and microglia in rat brain.
The Journal of experimental medicine 1987;166(4):1138-43.