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Siamon Gordon
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31
Brown, Gordon
24
Martinez-Pomares, Luisa
24
Taylor, Philip
23
Lin, Hsi-Hsien
18
Greaves, David
18
Stacey, Martin
16
Perry, Hugh
16
McKnight, Andrew
14
Willment, Janet
13
Platt, Nick
13
Crocker, Paul
11
Williams, David
11
Wong, Simon
11
Keshav, Satish
10
Chang, Gin-Wen
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All Publications
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2009: Helming Laura; Gordon Siamon
Molecular mediators of macrophage fusion.
Trends in cell biology 2009;19(10):514-22.
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2009: Seeds Rosalind E; Gordon Siamon; Miller Joanna L
Characterisation of myeloid receptor expression and interferon alpha/beta production in murine plasmacytoid dendritic cells by flow cytomtery.
Journal of immunological methods 2009;350(1-2):106-17.
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2009: van der Zanden Esmerij P; Snoek Susanne A; Heinsbroek Sigrid E; Stanisor Oana I; Verseijden Caroline; Boeckxstaens Guy E; Peppelenbosch Maikel P; Greaves David R; Gordon Siamon; De Jonge Wouter J
Vagus nerve activity augments intestinal macrophage phagocytosis via nicotinic acetylcholine receptor alpha4beta2.
Gastroenterology 2009;137(3):1029-39, 1039.e1-4.
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2009: Areschoug Thomas; Gordon Siamon
Scavenger receptors: role in innate immunity and microbial pathogenesis.
Cellular microbiology 2009;11(8):1160-9.
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2009: Bowdish Dawn M E; Sakamoto Kaori; Kim Mi-Jeong; Kroos Mariliis; Mukhopadhyay Subhankar; Leifer Cynthia A; Tryggvason Karl; Gordon Siamon; Russell David G
MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.
PLoS pathogens 2009;5(6):e1000474.
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2009: Greaves David R; Gordon Siamon
The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges.
Journal of lipid research 2009;50 Suppl():S282-6.
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2009: Ozment-Skelton Tammy R; deFluiter Elizabeth A; Ha Tuanzhu; Li Chuanfu; Graves Bridget M; Ferguson Donald A; Schweitzer John B; Preizsner Johanna; Brown Gordon D; Gordon Siamon; Kalbfleisch John H; Williams David L
Leukocyte Dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis.
Critical care medicine 2009;37(3):1038-45.
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2009: Haisma Hidde J; Boesjes Marije; Beerens Antoine M; van der Strate Barry W A; Curiel David T; Plüddemann Annette; Gordon Siamon; Bellu Anna Rita
Scavenger receptor A: a new route for adenovirus 5.
Molecular pharmaceutics 2009;6(2):366-74.
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2009: Gordon Siamon; Trinchieri Giorgio
Innate resistance and inflammation.
Current opinion in immunology 2009;21(1):1-2.
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2009: Plüddemann Annette; Hoe J Claire; Makepeace Katherine; Moxon E Richard; Gordon Siamon
The macrophage scavenger receptor A is host-protective in experimental meningococcal septicaemia.
PLoS pathogens 2009;5(2):e1000297.
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2009: Helming Laura; Winter Julia; Gordon Siamon
The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion.
Journal of cell science 2009;122(Pt 4):453-9.
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2009: deSchoolmeester Matthew L; Martinez-Pomares Luisa; Gordon Siamon; Else Kathryn J
The mannose receptor binds Trichuris muris excretory/secretory proteins but is not essential for protective immunity.
Immunology 2009;126(2):246-55.
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2009: Bowdish Dawn M E; Gordon Siamon
Conserved domains of the class A scavenger receptors: evolution and function.
Immunological reviews 2009;227(1):19-31.
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2009: Mukhopadhyay Subhankar; Plüddemann Annette; Gordon Siamon
Macrophage pattern recognition receptors in immunity, homeostasis and self tolerance.
Advances in experimental medicine and biology 2009;653():1-14.
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2009: Heinsbroek Sigrid E M; Gordon Siamon
The role of macrophages in inflammatory bowel diseases.
Expert reviews in molecular medicine 2009;11():e14.
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2009: Lin Hsi-Hsien; Chang Gin-Wen; Huang Yi-Shu; Hsiao Cheng-Chih; Stacey Martin; Gordon Siamon
Multivalent protein probes for the identification and characterization of cognate cellular ligands for myeloid cell surface receptors.
Methods in molecular biology (Clifton, N.J.) 2009;531():89-101.
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2009: Martinez Fernando O; Helming Laura; Gordon Siamon
Alternative activation of macrophages: an immunologic functional perspective.
Annual review of immunology 2009;27():451-83.
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2008: Gordon Siamon
Elie Metchnikoff: father of natural immunity.
European journal of immunology 2008;38(12):3257-64.
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2008: Heinsbroek Sigrid E M; Taylor Philip R; Martinez Fernando O; Martinez-Pomares Luisa; Brown Gordon D; Gordon Siamon
Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis.
PLoS pathogens 2008;4(11):e1000218.
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2008: Areschoug Thomas; Waldemarsson Johan; Gordon Siamon
Evasion of macrophage scavenger receptor A-mediated recognition by pathogenic streptococci.
European journal of immunology 2008;38(11):3068-79.
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2008: Yona Simon; Lin Hsi-Hsien; Siu Willie O; Gordon Siamon; Stacey Martin
Adhesion-GPCRs: emerging roles for novel receptors.
Trends in biochemical sciences 2008;33(10):491-500.
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2008: Pyz Elwira; Huysamen Cristal; Marshall Andrew S J; Gordon Siamon; Taylor Philip R; Brown Gordon D
Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand.
European journal of immunology 2008;38(4):1157-63.
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2008: Adams Elizabeth L; Rice Peter J; Graves Bridget; Ensley Harry E; Yu Hai; Brown Gordon D; Gordon Siamon; Monteiro Mario A; Papp-Szabo Erzsebet; Lowman Douglas W; Power Trevor D; Wempe Michael F; Williams David L
Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side-chain branching.
The Journal of pharmacology and experimental therapeutics 2008;325(1):115-23.
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2008: Chiu Pei-Ling; Ng Boon Han; Chang Gin-Wen; Gordon Siamon; Lin Hsi-Hsien
Putative alternative trans-splicing of leukocyte adhesion-GPCR pre-mRNAs generates functional chimeric receptors.
FEBS letters 2008;582(5):792-8.
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2008: Yona Simon; Lin Hsi-Hsien; Dri Pietro; Davies John Q; Hayhoe Richard P G; Lewis Sion M; Heinsbroek Sigrid E M; Brown K Alun; Perretti Mauro; Hamann Jörg; Treacher David F; Gordon Siamon; Stacey Martin
Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):741-51.
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2008: Miller Joanna L; deWet Barend J M; Martinez-Pomares Luisa; Radcliffe Catherine M; Dwek Raymond A; Rudd Pauline M; Gordon Siamon
The mannose receptor mediates dengue virus infection of macrophages.
PLoS pathogens 2008;4(2):e17.
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2008: Dennehy Kevin M; Ferwerda Gerben; Faro-Trindade Inês; Pyz Elwira; Willment Janet A; Taylor Philip R; Kerrigan Ann; Tsoni S Vicky; Gordon Siamon; Meyer-Wentrup Friederike; Adema Gosse J; Kullberg Bart-Jan; Schweighoffer Edina; Tybulewicz Victor; Mora-Montes Hector M; Gow Neil A R; Williams David L; Netea Mihai G; Brown Gordon D
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.
European journal of immunology 2008;38(2):500-6.
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2008: Plüddemann Annette; Neyen Claudine; Gordon Siamon; Peiser Leanne
A sensitive solid-phase assay for identification of class A macrophage scavenger receptor ligands using cell lysate.
Journal of immunological methods 2008;329(1-2):167-75.
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2008: Helming Laura; Tomasello Elena; Kyriakides Themis R; Martinez Fernando O; Takai Toshiyuki; Gordon Siamon; Vivier Eric
Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.
Science signaling 2008;1(43):ra11.
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2008: Areschoug Thomas; Gordon Siamon
Pattern recognition receptors and their role in innate immunity: focus on microbial protein ligands.
Contributions to microbiology 2008;15():45-60.
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2008: Martinez-Pomares Luisa; Gordon Siamon
Murine macrophages: a technical approach.
Methods in molecular biology (Clifton, N.J.) 2008;415():255-72.
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2007: Bowdish D M E; Loffredo M S; Mukhopadhyay S; Mantovani Alberto; Gordon S
Macrophage receptors implicated in the "adaptive" form of innate immunity.
Microbes and infection / Institut Pasteur 2007;9(14-15):1680-7.
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2007: Martinez-Pomares Luisa; Gordon Siamon
Antigen presentation the macrophage way.
Cell 2007;131(4):641-3.
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2007: Gordon Siamon
The macrophage: past, present and future.
European journal of immunology 2007;37 Suppl 1():S9-17.
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2007: Plüddemann Annette; Neyen Claudine; Gordon Siamon
Macrophage scavenger receptors and host-derived ligands.
Methods (San Diego, Calif.) 2007;43(3):207-17.
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2007: Hamann Jörg; Koning Nathalie; Pouwels Walter; Ulfman Laurien H; van Eijk Marco; Stacey Martin; Lin Hsi-Hsien; Gordon Siamon; Kwakkenbos Mark J
EMR1, the human homolog of F4/80, is an eosinophil-specific receptor.
European journal of immunology 2007;37(10):2797-802.
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2007: Rosas Marcela; Gordon Siamon; Taylor Philip R
Characterisation of the expression and function of the GM-CSF receptor alpha-chain in mice.
European journal of immunology 2007;37(9):2518-28.
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2007: Davies John Q; Chang Gin-Wen; Yona Simon; Gordon Siamon; Stacey Martin; Lin Hsi-Hsien
The role of receptor oligomerization in modulating the expression and function of leukocyte adhesion-G protein-coupled receptors.
The Journal of biological chemistry 2007;282(37):27343-53.
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2007: Griffiths Samantha; Portman Neil; Taylor Philip R; Gordon Siamon; Ginger Michael L; Gull Keith
RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection.
Eukaryotic cell 2007;6(7):1248-50.
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2007: Brown James; O'Callaghan Chris A; Marshall Andrew S J; Gilbert Robert J C; Siebold Christian; Gordon Siamon; Brown Gordon D; Jones E Yvonne
Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.
Protein science : a publication of the Protein Society 2007;16(6):1042-52.
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2007: Nedvetzki Shlomo; Sowinski Stefanie; Eagle Robert A; Harris James; Vély Frédéric; Pende Daniela; Trowsdale John; Vivier Eric; Gordon Siamon; Davis Daniel M
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.
Blood 2007;109(9):3776-85.
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2007: McKenzie Emma J; Taylor Philip R; Stillion Richard J; Lucas Andrew D; Harris James; Gordon Siamon; Martinez-Pomares Luisa
Mannose receptor expression and function define a new population of murine dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):4975-83.
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2007: Yona Simon; Gordon Siamon
Inflammation: Glucocorticoids turn the monocyte switch.
Immunology and cell biology 2007;85(2):81-2.
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2007: Chang Gin-Wen; Davies John Q; Stacey Martin; Yona Simon; Bowdish Dawn M E; Hamann Jörg; Chen Tse-Ching; Lin Chun-Yen; Gordon Siamon; Lin Hsi-Hsien
CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells.
Biochemical and biophysical research communications 2007;353(1):133-8.
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2007: Gordon Siamon
Macrophage heterogeneity and tissue lipids.
The Journal of clinical investigation 2007;117(1):89-93.
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2007: Taylor Philip R; Tsoni S Vicky; Willment Janet A; Dennehy Kevin M; Rosas Marcela; Findon Helen; Haynes Ken; Steele Chad; Botto Marina; Gordon Siamon; Brown Gordon D
Dectin-1 is required for beta-glucan recognition and control of fungal infection.
Nature immunology 2007;8(1):31-8.
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2007: Helming Laura; Gordon Siamon
Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules.
European journal of immunology 2007;37(1):33-42.
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2007: Helming Laura; Gordon Siamon
The molecular basis of macrophage fusion.
Immunobiology 2007;212(9-10):785-93.
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2006: Martinez Fernando O; Gordon Siamon; Locati Massimo; Mantovani Alberto
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7303-11.
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2006: Peiser Leanne; Makepeace Katherine; Plüddemann Annette; Savino Silvana; Wright J Claire; Pizza Mariagrazia; Rappuoli Rino; Moxon E Richard; Gordon Siamon
Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay.
Infection and immunity 2006;74(9):5191-9.
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2006: Marshall Andrew S J; Willment Janet A; Pyz Elwira; Dennehy Kevin M; Reid Delyth M; Dri Pietro; Gordon Siamon; Wong Simon Y C; Brown Gordon D
Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation.
European journal of immunology 2006;36(8):2159-69.
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2006: Ozment-Skelton Tammy R; Goldman Matthew P; Gordon Siamon; Brown Gordon D; Williams David L
Prolonged reduction of leukocyte membrane-associated Dectin-1 levels following beta-glucan administration.
The Journal of pharmacology and experimental therapeutics 2006;318(2):540-6.
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2006: Graham Lisa M; Tsoni S Vicky; Willment Janet A; Williams David L; Taylor Philip R; Gordon Siamon; Dennehy Kevin; Brown Gordon D
Soluble Dectin-1 as a tool to detect beta-glucans.
Journal of immunological methods 2006;314(1-2):164-9.
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2006: Capasso Melania; Durrant Lindy G; Stacey Martin; Gordon Siamon; Ramage Judith; Spendlove Ian
Costimulation via CD55 on human CD4+ T cells mediated by CD97.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1070-7.
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2006: Xia Zhidao; Taylor Philip R; Locklin Rachel M; Gordon Siamon; Cui Zhanfeng; Triffitt James T
Innate immune response to human bone marrow fibroblastic cell implantation in CB17 scid/beige mice.
Journal of cellular biochemistry 2006;98(4):966-80.
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2006: Yona Simon; Heinsbroek Sigrid E M; Peiser Leanne; Gordon Siamon; Perretti Mauro; Flower Roderick J
Impaired phagocytic mechanism in annexin 1 null macrophages.
British journal of pharmacology 2006;148(4):469-77.
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2006: Heinsbroek Sigrid E M; Taylor Philip R; Rosas Marcela; Willment Janet A; Williams David L; Gordon Siamon; Brown Gordon D
Expression of functionally different dectin-1 isoforms by murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5513-8.
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2006: Martinez-Pomares Luisa; Wienke Dirk; Stillion Richard; McKenzie Emma J; Arnold James N; Harris James; McGreal Eamon; Sim Robert B; Isacke Clare M; Gordon Siamon
Carbohydrate-independent recognition of collagens by the macrophage mannose receptor.
European journal of immunology 2006;36(5):1074-82.
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2006: McGreal Eamon P; Rosas Marcela; Brown Gordon D; Zamze Susanne; Wong Simon Y C; Gordon Siamon; Martinez-Pomares Luisa; Taylor Philip R
The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose.
Glycobiology 2006;16(5):422-30.
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2006: Hagemann Thorsten; Wilson Julia; Burke Frances; Kulbe Hagen; Li Ninfeng Fiona; Plüddemann Annette; Charles Kellie; Gordon Siamon; Balkwill Frances R
Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):5023-32.
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2006: Becker Mike; Cotena Alessia; Gordon Siamon; Platt Nick
Expression of the class A macrophage scavenger receptor on specific subpopulations of murine dendritic cells limits their endotoxin response.
European journal of immunology 2006;36(4):950-60.
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2006: Mukhopadhyay Subhankar; Chen Yunying; Sankala Marko; Peiser Leanne; Pikkarainen Timo; Kraal Georg; Tryggvason Karl; Gordon Siamon
MARCO, an innate activation marker of macrophages, is a class A scavenger receptor for Neisseria meningitidis.
European journal of immunology 2006;36(4):940-9.
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2006: Boskovic Jasminka; Arnold James N; Stilion Richard; Gordon Siamon; Sim Robert B; Rivera-Calzada Angel; Wienke Dirk; Isacke Clare M; Martinez-Pomares Luisa; Llorca Oscar
Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor.
The Journal of biological chemistry 2006;281(13):8780-7.
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2006: Suram Saritha; Brown Gordon D; Ghosh Moumita; Gordon Siamon; Loper Robyn; Taylor Philip R; Akira Shizuo; Uematsu Satoshi; Williams David L; Leslie Christina C
Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor.
The Journal of biological chemistry 2006;281(9):5506-14.
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2006: Palma Angelina S; Feizi Ten; Zhang Yibing; Stoll Mark S; Lawson Alexander M; Díaz-Rodríguez Esther; Campanero-Rhodes María Asunción; Costa Júlia; Gordon Siamon; Brown Gordon D; Chai Wengang
Ligands for the beta-glucan receptor, Dectin-1, assigned using "designer" microarrays of oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides.
The Journal of biological chemistry 2006;281(9):5771-9.
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2006: Harris James; Schwinn Nicole; Mahoney James A; Lin Hsi-Hsien; Shaw Michael; Howard Chris J; da Silva Rosangela P; Gordon Siamon
A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles.
International journal of experimental pathology 2006;87(1):29-39.
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2006: Plüddemann Annette; Mukhopadhyay Subhankar; Gordon Siamon
The interaction of macrophage receptors with bacterial ligands.
Expert reviews in molecular medicine 2006;8(28):1-25.
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2006: Seeds Rosalind E; Gordon Siamon; Miller Joanna L
Receptors and ligands involved in viral induction of type I interferon production by plasmacytoid dendritic cells.
Immunobiology 2006;211(6-8):525-35.
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2006: Pyz Elwira; Marshall Andrew S J; Gordon Siamon; Brown Gordon D
C-type lectin-like receptors on myeloid cells.
Annals of medicine 2006;38(4):242-51.
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2005: Steele Chad; Rapaka Rekha R; Metz Allison; Pop Shannon M; Williams David L; Gordon Siamon; Kolls Jay K; Brown Gordon D
The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus.
PLoS pathogens 2005;1(4):e42.
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2005: Gordon Siamon; Taylor Philip R
Monocyte and macrophage heterogeneity.
Nature reviews. Immunology 2005;5(12):953-64.
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2005: Szabó Rita; Peiser Leanne; Plüddemann Annette; Bösze Szilvia; Heinsbroek Sigrid; Gordon Siamon; Hudecz Ferenc
Uptake of branched polypeptides with poly[L-lys] backbone by bone-marrow culture-derived murine macrophages: the role of the class a scavenger receptor.
Bioconjugate chemistry 2005;16(6):1442-50.
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2005: Martinez-Pomares Luisa; Hanitsch Leif G; Stillion Richard; Keshav Satish; Gordon Siamon
Expression of mannose receptor and ligands for its cysteine-rich domain in venous sinuses of human spleen.
Laboratory investigation; a journal of technical methods and pathology 2005;85(10):1238-49.
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2005: Su Yunpeng; Bakker Talitha; Harris James; Tsang Clarence; Brown Gordon D; Wormald Mark R; Gordon Siamon; Dwek Raymond A; Rudd Pauline M; Martinez-Pomares Luisa
Glycosylation influences the lectin activities of the macrophage mannose receptor.
The Journal of biological chemistry 2005;280(38):32811-20.
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2005: Rice Peter J; Adams Elizabeth L; Ozment-Skelton Tammy; Gonzalez Andres J; Goldman Matthew P; Lockhart Brent E; Barker Luke A; Breuel Kevin F; Deponti Warren K; Kalbfleisch John H; Ensley Harry E; Brown Gordon D; Gordon Siamon; Williams David L
Oral delivery and gastrointestinal absorption of soluble glucans stimulate increased resistance to infectious challenge.
The Journal of pharmacology and experimental therapeutics 2005;314(3):1079-86.
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2005: Taylor Philip R; Reid Delyth M; Heinsbroek Sigrid E M; Brown Gordon D; Gordon Siamon; Wong Simon Y C
Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo.
European journal of immunology 2005;35(7):2163-74.
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2005: Heinsbroek Sigrid E M; Brown Gordon D; Gordon Siamon
Dectin-1 escape by fungal dimorphism.
Trends in immunology 2005;26(7):352-4.
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2005: Cheung Chung Y; Poon Leo L M; Ng Iris H Y; Luk Winsie; Sia Sin-Fun; Wu Mavis H S; Chan Kwok-Hung; Yuen Kwok-Yung; Gordon Siamon; Guan Yi; Peiris Joseph S M
Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis.
Journal of virology 2005;79(12):7819-26.
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2005: Linehan Sheena A; Weber Roberta; McKercher Scott; Ripley Ruth M; Gordon Siamon; Martin Paul
Enhanced expression of the mannose receptor by endothelial cells of the liver and spleen microvascular beds in the macrophage-deficient PU.1 null mouse.
Histochemistry and cell biology 2005;123(4-5):365-76.
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2005: Lin Hsi-Hsien; Stacey Martin; Chang Gin-Wen; Davies John Q; Gordon Siamon
Method for selecting and enriching cells expressing low affinity ligands for cell surface receptors.
BioTechniques 2005;38(5):696, 698.
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2005: Lin Hsi-Hsien; Faunce Douglas E; Stacey Martin; Terajewicz Ania; Nakamura Takahiko; Zhang-Hoover Jie; Kerley Marilyn; Mucenski Michael L; Gordon Siamon; Stein-Streilein Joan
The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance.
The Journal of experimental medicine 2005;201(10):1615-25.
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2005: Willment Janet A; Marshall Andrew S J; Reid Delyth M; Williams David L; Wong Simon Y C; Gordon Siamon; Brown Gordon D
The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells.
European journal of immunology 2005;35(5):1539-47.
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2005: Rogers Neil C; Slack Emma C; Edwards Alexander D; Nolte Martijn A; Schulz Oliver; Schweighoffer Edina; Williams David L; Gordon Siamon; Tybulewicz Victor L; Brown Gordon D; Reis e Sousa Caetano
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins.
Immunity 2005;22(4):507-17.
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2005: Brown Gordon D; Gordon Siamon
Immune recognition of fungal beta-glucans.
Cellular microbiology 2005;7(4):471-9.
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2005: Yoshitomi Hiroyuki; Sakaguchi Noriko; Kobayashi Katsuya; Brown Gordon D; Tagami Tomoyuki; Sakihama Toshiko; Hirota Keiji; Tanaka Satoshi; Nomura Takashi; Miki Ichiro; Gordon Siamon; Akira Shizuo; Nakamura Takashi; Sakaguchi Shimon
A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice.
The Journal of experimental medicine 2005;201(6):949-60.
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2005: Taylor Philip R; Gordon Siamon; Martinez-Pomares Luisa
The mannose receptor: linking homeostasis and immunity through sugar recognition.
Trends in immunology 2005;26(2):104-10.
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2005: McGreal Eamon P; Miller Joanna L; Gordon Siamon
Ligand recognition by antigen-presenting cell C-type lectin receptors.
Current opinion in immunology 2005;17(1):18-24.
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2005: Greaves David R; Gordon Siamon
Thematic review series: the immune system and atherogenesis. Recent insights into the biology of macrophage scavenger receptors.
Journal of lipid research 2005;46(1):11-20.
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2005: Kwakkenbos Mark J; Pouwels Walter; Matmati Mourad; Stacey Martin; Lin Hsi-Hsien; Gordon Siamon; van Lier René A W; Hamann Jörg
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells.
Journal of leukocyte biology 2005;77(1):112-9.
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2005: Su Yunpeng Roc; Tsang Clarence; Bakker Talitha; Harris James; Gordon Siamon; Dwek Raymond A; Martinez-Pomares Luisa; Rudd Pauline M
Glycosylation influences the ligand binding activities of mannose receptor.
Advances in experimental medicine and biology 2005;564():25-6.
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2005: Davies John Q; Gordon Siamon
Isolation and culture of human macrophages.
Methods in molecular biology (Clifton, N.J.) 2005;290():105-16.
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2005: Davies John Q; Gordon Siamon
Isolation and culture of murine macrophages.
Methods in molecular biology (Clifton, N.J.) 2005;290():91-103.
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2004: O'Reilly Dawn; Addley Mark; Quinn Carmel; MacFarlane Alison J; Gordon Siamon; McKnight Andrew J; Greaves David R
Functional analysis of the murine Emr1 promoter identifies a novel purine-rich regulatory motif required for high-level gene expression in macrophages.
Genomics 2004;84(6):1030-40.
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2004: Herre Jurgen; Marshall Andrew S J; Caron Emmanuelle; Edwards Alexander D; Williams David L; Schweighoffer Edina; Tybulewicz Victor; Reis e Sousa Caetano; Gordon Siamon; Brown Gordon D
Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages.
Blood 2004;104(13):4038-45.
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2004: Cotena Alessia; Gordon Siamon; Platt Nick
The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6427-32.
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2004: McGreal Eamon P; Martinez-Pomares Luisa; Gordon Siamon
Divergent roles for C-type lectins expressed by cells of the innate immune system.
Molecular immunology 2004;41(11):1109-21.
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2004: Mukhopadhyay Subhankar; Peiser Leanne; Gordon Siamon
Activation of murine macrophages by Neisseria meningitidis and IFN-gamma in vitro: distinct roles of class A scavenger and Toll-like pattern recognition receptors in selective modulation of surface phenotype.
Journal of leukocyte biology 2004;76(3):577-84.
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2004: Mukhopadhyay Subhankar; Herre Jurgen; Brown Gordon D; Gordon Siamon
The potential for Toll-like receptors to collaborate with other innate immune receptors.
Immunology 2004;112(4):521-30.
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2004: Lin Hsi-Hsien; Chang Gin-Wen; Davies John Q; Stacey Martin; Harris James; Gordon Siamon
Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif.
The Journal of biological chemistry 2004;279(30):31823-32.
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2004: Reid Delyth M; Montoya Maria; Taylor Philip R; Borrow Persephone; Gordon Siamon; Brown Gordon D; Wong Simon Y C
Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions.
Journal of leukocyte biology 2004;76(1):86-94.
-
2004: Gordon Siamon
Pathogen recognition or homeostasis? APC receptor functions in innate immunity.
Comptes rendus biologies 2004;327(6):603-7.
-
2004: Garbi Natalio; Arnold Bernd; Gordon Siamon; Hämmerling Günter J; Ganss Ruth
CpG motifs as proinflammatory factors render autochthonous tumors permissive for infiltration and destruction.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):5861-9.
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2004: Bhakta Sanjib; Besra Gurdyal S; Upton Anna M; Parish Tanya; Sholto-Douglas-Vernon Carolyn; Gibson Kevin J C; Knutton Stuart; Gordon Siamon; DaSilva Rosangela P; Anderton Matthew C; Sim Edith
Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target.
The Journal of experimental medicine 2004;199(9):1191-9.
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2004: Marshall Andrew S J; Willment Janet A; Lin Hsi-Hsien; Williams David L; Gordon Siamon; Brown Gordon D
Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes.
The Journal of biological chemistry 2004;279(15):14792-802.
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2004: Taylor Philip R; Zamze Susanne; Stillion Richard J; Wong Simon Y C; Gordon Siamon; Martinez-Pomares Luisa
Development of a specific system for targeting protein to metallophilic macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1963-8.
-
2004: Herre Jürgen; Gordon Siamon; Brown Gordon D
Dectin-1 and its role in the recognition of beta-glucans by macrophages.
Molecular immunology 2004;40(12):869-76.
-
2004: Marshall Andrew S J; Gordon Siamon
Commentary: C-type lectins on the macrophage cell surface--recent findings.
European journal of immunology 2004;34(1):18-24.
-
2004: Taylor Philip R; Brown Gordon D; Herre Jurgen; Williams David L; Willment Janet A; Gordon Siamon
The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1157-62.
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2004: Kwakkenbos Mark J; Kop Else N; Stacey Martin; Matmati Mourad; Gordon Siamon; Lin Hsi-Hsien; Hamann Jörg
The EGF-TM7 family: a postgenomic view.
Immunogenetics 2004;55(10):655-66.
-
2004: Herre Jurgen; Willment Janet A; Gordon Siamon; Brown Gordon D
The role of Dectin-1 in antifungal immunity.
Critical reviews in immunology 2004;24(3):193-203.
-
2004: Mukhopadhyay Subhankar; Gordon Siamon
The role of scavenger receptors in pathogen recognition and innate immunity.
Immunobiology 2004;209(1-2):39-49.
-
2004: Gordon Siamon
Cancer and inflammation. Introduction.
Novartis Foundation symposium 2004;256():1-5.
-
2003: Stanton Lee-Anne; Fenhalls Gael; Lucas Andrew; Gough Peter; Greaves David R; Mahoney James A; Helden Paul van; Gordon Siamon
Immunophenotyping of macrophages in human pulmonary tuberculosis and sarcoidosis.
International journal of experimental pathology 2003;84(6):289-304.
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2003: Steele Chad; Marrero Luis; Swain Steve; Harmsen Allen G; Zheng Mingquan; Brown Gordon D; Gordon Siamon; Shellito Judd E; Kolls Jay K
Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor.
The Journal of experimental medicine 2003;198(11):1677-88.
-
2003: Khati Makobetsa; Schüman Michael; Ibrahim Jamal; Sattentau Quentin; Gordon Siamon; James William
Neutralization of infectivity of diverse R5 clinical isolates of human immunodeficiency virus type 1 by gp120-binding 2'F-RNA aptamers.
Journal of virology 2003;77(23):12692-8.
-
2003: Gordon Siamon
Do macrophage innate immune receptors enhance atherogenesis?
Developmental cell 2003;5(5):666-8.
-
2003: Willment Janet A; Lin Hsi-Hsien; Reid Delyth M; Taylor Philip R; Williams David L; Wong Simon Y C; Gordon Siamon; Brown Gordon D
Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4569-73.
-
2003: Stacey Martin; Chang Gin-Wen; Davies John Q; Kwakkenbos Mark J; Sanderson Ralph D; Hamann Jörg; Gordon Siamon; Lin Hsi-Hsien
The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans.
Blood 2003;102(8):2916-24.
-
2003: Brown Gordon D; Gordon Siamon
Fungal beta-glucans and mammalian immunity.
Immunity 2003;19(3):311-5.
-
2003: Linehan Sheena A; Coulson Patricia S; Wilson R Alan; Mountford Adrian P; Brombacher Frank; Martínez-Pomares Luisa; Gordon Siamon
IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni.
Laboratory investigation; a journal of technical methods and pathology 2003;83(8):1223-31.
-
2003: Taylor Philip R; Brown Gordon D; Geldhof Anja B; Martinez-Pomares Luisa; Gordon Siamon
Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo.
European journal of immunology 2003;33(8):2090-7.
-
2003: Taylor Philip R; Gordon Siamon
Monocyte heterogeneity and innate immunity.
Immunity 2003;19(1):2-4.
-
2003: Chang Gin-Wen; Stacey Martin; Kwakkenbos Mark J; Hamann Jörg; Gordon Siamon; Lin Hsi-Hsien
Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif.
FEBS letters 2003;547(1-3):145-50.
-
2003: O'Reilly Dawn; Quinn Carmel M; El-Shanawany Tariq; Gordon Siamon; Greaves David R
Multiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific manner.
The Journal of biological chemistry 2003;278(24):21909-19.
-
2003: Brown Gordon D; Herre Jurgen; Williams David L; Willment Janet A; Marshall Andrew S J; Gordon Siamon
Dectin-1 mediates the biological effects of beta-glucans.
The Journal of experimental medicine 2003;197(9):1119-24.
-
2003: Martinez-Pomares Luisa; Reid Delyth M; Brown Gordon D; Taylor Philip R; Stillion Richard J; Linehan Sheena A; Zamze Susanne; Gordon Siamon; Wong Simon Y C
Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies.
Journal of leukocyte biology 2003;73(5):604-13.
-
2003: Gordon Siamon
Alternative activation of macrophages.
Nature reviews. Immunology 2003;3(1):23-35.
-
2002: Gordon Siamon
Pattern recognition receptors: doubling up for the innate immune response.
Cell 2002;111(7):927-30.
-
2002: Gordon Siamon
Positive about HIV--an immunological education project in South Africa.
Nature immunology 2002;3(12):1115-7.
-
2002: Schaller Evelyne; Macfarlane Alison J; Rupec Rudolf A; Gordon Siamon; McKnight Andrew J; Pfeffer Klaus
Inactivation of the F4/80 glycoprotein in the mouse germ line.
Molecular and cellular biology 2002;22(22):8035-43.
-
2002: Zamze Susanne; Martinez-Pomares Luisa; Jones Hannah; Taylor Philip R; Stillion Richard J; Gordon Siamon; Wong Simon Y C
Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor.
The Journal of biological chemistry 2002;277(44):41613-23.
-
2002: Taylor Philip R; Brown Gordon D; Reid Delyth M; Willment Janet A; Martinez-Pomares Luisa; Gordon Siamon; Wong Simon Y C
The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3876-82.
-
2002: Peiser Leanne; De Winther Menno P J; Makepeace Katherine; Hollinshead Michael; Coull Philip; Plested Joyce; Kodama Tatsuhiko; Moxon E Richard; Gordon Siamon
The class A macrophage scavenger receptor is a major pattern recognition receptor for Neisseria meningitidis which is independent of lipopolysaccharide and not required for secretory responses.
Infection and immunity 2002;70(10):5346-54.
-
2002: Brown Gordon D; Taylor Philip R; Reid Delyth M; Willment Janet A; Williams David L; Martinez-Pomares Luisa; Wong Simon Y C; Gordon Siamon
Dectin-1 is a major beta-glucan receptor on macrophages.
The Journal of experimental medicine 2002;196(3):407-12.
-
2002: Stacey Martin; Chang Gin-Wen; Sanos Stephanie L; Chittenden Laura R; Stubbs Lisa; Gordon Siamon; Lin Hsi-Hsien
EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20.
The Journal of biological chemistry 2002;277(32):29283-93.
-
2002: Greaves David R; Gordon Siamon
Macrophage-specific gene expression: current paradigms and future challenges.
International journal of hematology 2002;76(1):6-15.
-
2002: Taylor Philip R; Pickering Matthew C; Kosco-Vilbois Marie H; Walport Mark J; Botto Marina; Gordon Siamon; Martinez-Pomares Luisa
The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.
European journal of immunology 2002;32(7):1888-96.
-
2002: Kwakkenbos Mark J; Chang Gin-Wen; Lin Hsi-Hsien; Pouwels Walter; de Jong Esther C; van Lier René A W; Gordon Siamon; Hamann Jörg
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells.
Journal of leukocyte biology 2002;71(5):854-62.
-
2002: Yu Ping; Wang Yang; Chin Robert K; Martinez-Pomares Luisa; Gordon Siamon; Kosco-Vibois Marie H; Cyster Jason; Fu Yang-Xin
B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5117-23.
-
2002: Wreschner Daniel H; McGuckin Michael A; Williams Stefanie J; Baruch Amos; Yoeli Merav; Ziv Ravit; Okun Liron; Zaretsky Joseph; Smorodinsky Nechama; Keydar Iafa; Neophytou Pavlos; Stacey Martin; Lin His-Hsien; Gordon Siamon
Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins.
Protein science : a publication of the Protein Society 2002;11(3):698-706.
-
2002: Balch S G; Greaves D R; Gordon S; McKnight A J
Organization of the mouse macrophage C-type lectin (Mcl) gene and identification of a subgroup of related lectin molecules.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2002;29(1):61-4.
-
2002: Peiser Leanne; Mukhopadhyay Subhankar; Gordon Siamon
Scavenger receptors in innate immunity.
Current opinion in immunology 2002;14(1):123-8.
-
2002: Platt Nick; Haworth Richard; Darley Liz; Gordon Siamon
The many roles of the class A macrophage scavenger receptor.
International review of cytology 2002;212():1-40.
-
2001: Martinez-Pomares L; Linehan S A; Taylor P R; Gordon S
Binding properties of the mannose receptor.
Immunobiology 2001;204(5):527-35.
-
2001: Willment J A; Gordon S; Brown G D
Characterization of the human beta -glucan receptor and its alternatively spliced isoforms.
The Journal of biological chemistry 2001;276(47):43818-23.
-
2001: Brown G D; Gordon S
Immune recognition. A new receptor for beta-glucans.
Nature 2001;413(6851):36-7.
-
2001: Platt N; Gordon S
Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse's tale.
The Journal of clinical investigation 2001;108(5):649-54.
-
2001: Gough P J; Gordon S; Greaves D R
The use of human CD68 transcriptional regulatory sequences to direct high-level expression of class A scavenger receptor in macrophages in vitro and in vivo.
Immunology 2001;103(3):351-61.
-
2001: Linehan S A; Martínez-Pomares L; da Silva R P; Gordon S
Endogenous ligands of carbohydrate recognition domains of the mannose receptor in murine macrophages, endothelial cells and secretory cells; potential relevance to inflammation and immunity.
European journal of immunology 2001;31(6):1857-66.
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2001: Greaves D R; Häkkinen T; Lucas A D; Liddiard K; Jones E; Quinn C M; Senaratne J; Green F R; Tyson K; Boyle J; Shanahan C; Weissberg P L; Gordon S; Ylä-Hertualla S
Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(6):923-9.
-
2001: Lin H H; Stacey M; Saxby C; Knott V; Chaudhry Y; Evans D; Gordon S; McKnight A J; Handford P; Lea S
Molecular analysis of the epidermal growth factor-like short consensus repeat domain-mediated protein-protein interactions: dissection of the CD97-CD55 complex.
The Journal of biological chemistry 2001;276(26):24160-9.
-
2001: Stacey M; Lin H H; Hilyard K L; Gordon S; McKnight A J
Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils.
The Journal of biological chemistry 2001;276(22):18863-70.
-
2001: Gordon S
Homeostasis: a scavenger receptor for haemoglobin.
Current biology : CB 2001;11(10):R399-401.
-
2001: Greaves D R; Gordon S
Immunity, atherosclerosis and cardiovascular disease.
Trends in immunology 2001;22(4):180-1.
-
2001: Mahoney J A; Ntolosi B; DaSilva R P; Gordon S; McKnight A J
Cloning and characterization of CPVL, a novel serine carboxypeptidase, from human macrophages.
Genomics 2001;72(3):243-51.
-
2001: Lucas A D; Chadwick N; Warren B F; Jewell D P; Gordon S; Powrie F; Greaves D R
The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo.
The American journal of pathology 2001;158(3):855-66.
-
2001: Peiser L; Gordon S
The function of scavenger receptors expressed by macrophages and their role in the regulation of inflammation.
Microbes and infection / Institut Pasteur 2001;3(2):149-59.
-
2001: Khati M; James W; Gordon S
HIV-macrophage interactions at the cellular and molecular level.
Archivum immunologiae et therapiae experimentalis 2001;49(5):367-78.
-
2000: Lin H H; Stacey M; Hamann J; Gordon S; McKnight A J
Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97.
Genomics 2000;67(2):188-200.
-
2000: Stacey M; Lin H H; Gordon S; McKnight A J
LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors.
Trends in biochemical sciences 2000;25(6):284-9.
-
2000: Platt N; Suzuki H; Kodama T; Gordon S
Apoptotic thymocyte clearance in scavenger receptor class A-deficient mice is apparently normal.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4861-7.
-
2000: Peiser L; Gough P J; Kodama T; Gordon S
Macrophage class A scavenger receptor-mediated phagocytosis of Escherichia coli: role of cell heterogeneity, microbial strain, and culture conditions in vitro.
Infection and immunity 2000;68(4):1953-63.
-
2000: Linehan S A; Martínez-Pomares L; Gordon S
Macrophage lectins in host defence.
Microbes and infection / Institut Pasteur 2000;2(3):279-88.
-
2000: Linehan S A; Martinez-Pomares L; Gordon S
Mannose receptor and scavenger receptor: two macrophage pattern recognition receptors with diverse functions in tissue homeostasis and host defense.
Advances in experimental medicine and biology 2000;479():1-14.
-
1999: Quinn C M; Wiles A P; El-Shanawany T; Catchpole I; Alnadaf T; Ford M J; Gordon S; Greaves D R
The human eukaryotic initiation factor 4AI gene (EIF4A1) contains multiple regulatory elements that direct high-level reporter gene expression in mammalian cell lines.
Genomics 1999;62(3):468-76.
-
1999: Martínez-Pomares L; Crocker P R; Da Silva R; Holmes N; Colominas C; Rudd P; Dwek R; Gordon S
Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor.
The Journal of biological chemistry 1999;274(49):35211-8.
-
1999: Linehan S A; Martínez-Pomares L; Stahl P D; Gordon S
Mannose receptor and its putative ligands in normal murine lymphoid and nonlymphoid organs: In situ expression of mannose receptor by selected macrophages, endothelial cells, perivascular microglia, and mesangial cells, but not dendritic cells.
The Journal of experimental medicine 1999;189(12):1961-72.
-
1999: Gough P J; Greaves D R; Suzuki H; Hakkinen T; Hiltunen M O; Turunen M; Herttuala S Y; Kodama T; Gordon S
Analysis of macrophage scavenger receptor (SR-A) expression in human aortic atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(3):461-71.
-
1999: da Silva R P; Gordon S
Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal protein.
The Biochemical journal 1999;338 ( Pt 3)():687-94.
-
1999: Platt N; da Silva R P; Gordon S
Class A scavenger receptors and the phagocytosis of apoptotic cells.
Immunology letters 1999;65(1-2):15-9.
-
1999: Martínez-Pomares L; Gordon S
Potential role of the mannose receptor in antigen transport.
Immunology letters 1999;65(1-2):9-13.
-
1999: Gordon S
Macrophage-restricted molecules: role in differentiation and activation.
Immunology letters 1999;65(1-2):5-8.
-
1999: van der Laan L J; Döpp E A; Haworth R; Pikkarainen T; Kangas M; Elomaa O; Dijkstra C D; Gordon S; Tryggvason K; Kraal G
Regulation and functional involvement of macrophage scavenger receptor MARCO in clearance of bacteria in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):939-47.
-
1998: Platt N; da Silva R P; Gordon S
Class A scavenger receptors and the phagocytosis of apoptotic cells.
Biochemical Society transactions 1998;26(4):639-44.
-
1998: Greaves D R; Quinn C M; Seldin M F; Gordon S
Functional comparison of the murine macrosialin and human CD68 promoters in macrophage and nonmacrophage cell lines.
Genomics 1998;54(1):165-8.
-
1998: Greaves D R; Gough P J; Gordon S
Recent progress in defining the role of scavenger receptors in lipid transport, atherosclerosis and host defence.
Current opinion in lipidology 1998;9(5):425-32.
-
1998: Jones E; Quinn C M; See C G; Montgomery D S; Ford M J; Kölble K; Gordon S; Greaves D R
The linked human elongation initiation factor 4A1 (EIF4A1) and CD68 genes map to chromosome 17p13.
Genomics 1998;53(2):248-50.
-
1998: Gordon S
The role of the macrophage in immune regulation.
Research in immunology 1998;149(7-8):685-8.
-
1998: Platt N; da Silva R P; Gordon S
Recognizing death: the phagocytosis of apoptotic cells.
Trends in cell biology 1998;8(9):365-72.
-
1998: Martínez-Pomares L; Mahoney J A; Káposzta R; Linehan S A; Stahl P D; Gordon S
A functional soluble form of the murine mannose receptor is produced by macrophages in vitro and is present in mouse serum.
The Journal of biological chemistry 1998;273(36):23376-80.
-
1998: Platt N; Gordon S
Scavenger receptors: diverse activities and promiscuous binding of polyanionic ligands.
Chemistry & biology 1998;5(8):R193-203.
-
1998: Balch S G; McKnight A J; Seldin M F; Gordon S
Cloning of a novel C-type lectin expressed by murine macrophages.
The Journal of biological chemistry 1998;273(29):18656-64.
-
1998: Hughes D A; Gordon S
Expression and function of the type 3 complement receptor in tissues of the developing mouse.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4543-52.
-
1998: de Villiers W J; Smith J D; Miyata M; Dansky H M; Darley E; Gordon S
Macrophage phenotype in mice deficient in both macrophage-colony-stimulating factor (op) and apolipoprotein E.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(4):631-40.
-
1998: Gough P J; Greaves D R; Gordon S
A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake.
Journal of lipid research 1998;39(3):531-43.
-
1998: McKnight A J; Gordon S
The EGF-TM7 family: unusual structures at the leukocyte surface.
Journal of leukocyte biology 1998;63(3):271-80.
-
1998: Clarke S; Gordon S
Myeloid-specific gene expression.
Journal of leukocyte biology 1998;63(2):153-68.
-
1998: McKnight A J; Gordon S
Membrane molecules as differentiation antigens of murine macrophages.
Advances in immunology 1998;68():271-314.
-
1997: McKnight A J; Macfarlane A J; Seldin M F; Gordon S
Chromosome mapping of the Emr1 gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(12):946.
-
1997: Mucklow S; Gordon S; Crocker P R
Characterization of the mouse sialoadhesin gene, Sn.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(12):934-7.
-
1997: Haworth R; Platt N; Keshav S; Hughes D; Darley E; Suzuki H; Kurihara Y; Kodama T; Gordon S
The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock.
The Journal of experimental medicine 1997;186(9):1431-9.
-
1997: Keshav S; McKnight A J; Arora R; Gordon S
Cloning of intestinal phospholipase A2 from intestinal epithelial RNA by differential display PCR.
Cell proliferation 1997;30(10-12):369-83.
-
1997: Greaves D R; Wang W; Dairaghi D J; Dieu M C; Saint-Vis B; Franz-Bacon K; Rossi D; Caux C; McClanahan T; Gordon S; Zlotnik A; Schall T J
CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.
The Journal of experimental medicine 1997;186(6):837-44.
-
1996: Martínez-Pomares L; Kosco-Vilbois M; Darley E; Tree P; Herren S; Bonnefoy J Y; Gordon S
Fc chimeric protein containing the cysteine-rich domain of the murine mannose receptor binds to macrophages from splenic marginal zone and lymph node subcapsular sinus and to germinal centers.
The Journal of experimental medicine 1996;184(5):1927-37.
-
1996: Herbein G; Montaner L J; Gordon S
Tumor necrosis factor alpha inhibits entry of human immunodeficiency virus type 1 into primary human macrophages: a selective role for the 75-kilodalton receptor.
Journal of virology 1996;70(11):7388-97.
-
1996: Kodama T; Doi T; Suzuki H; Takahashi K; Wada Y; Gordon S
Collagenous macrophage scavenger receptors.
Current opinion in lipidology 1996;7(5):287-91.
-
1996: Martinez-Pomares L; Platt N; McKnight A J; da Silva R P; Gordon S
Macrophage membrane molecules: markers of tissue differentiation and heterogeneity.
Immunobiology 1996;195(4-5):407-16.
-
1996: Platt N; Suzuki H; Kurihara Y; Kodama T; Gordon S
Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12456-60.
-
1996: McKnight A J; Gordon S
EGF-TM7: a novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules.
Immunology today 1996;17(6):283-7.
-
1996: Herbein G; Illei P; Montaner L J; James W; Gordon S
Comparison of p24 measurement by ELISA versus indicator cells for detecting residual HIV infectivity in vitro.
Journal of virological methods 1996;58(1-2):167-73.
-
1996: da Silva R P; Platt N; de Villiers J S; Gordon S
Membrane molecules and macrophage endocytosis: scavenger receptor and macrosialin as markers of plasma-membrane and vacuolar functions.
Biochemical Society transactions 1996;24(1):220-4.
-
1996: Clarke S; Greaves D R; Chung L P; Tree P; Gordon S
The human lysozyme promoter directs reporter gene expression to activated myelomonocytic cells in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1434-8.
-
1996: McKnight A J; Macfarlane A J; Dri P; Turley L; Willis A C; Gordon S
Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family.
The Journal of biological chemistry 1996;271(1):486-9.
-
1995: Herbein G; Doyle A G; Montaner L J; Gordon S
Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1 beta.
Clinical and experimental immunology 1995;102(2):430-7.
-
1995: Fischer P B; Collin M; Karlsson G B; James W; Butters T D; Davis S J; Gordon S; Dwek R A; Platt F M
The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding.
Journal of virology 1995;69(9):5791-7.
-
1995: Mucklow S; Hartnell A; Mattei M G; Gordon S; Crocker P R
Sialoadhesin (Sn) maps to mouse chromosome 2 and human chromosome 20 and is not linked to the other members of the sialoadhesin family, CD22, MAG, and CD33.
Genomics 1995;28(2):344-6.
-
1995: Hughes D A; Fraser I P; Gordon S
Murine macrophage scavenger receptor: in vivo expression and function as receptor for macrophage adhesion in lymphoid and non-lymphoid organs.
European journal of immunology 1995;25(2):466-73.
-
1995: Gordon S; Clarke S; Greaves D; Doyle A
Molecular immunobiology of macrophages: recent progress.
Current opinion in immunology 1995;7(1):24-33.
-
1995: Montaner L J; Herbein G; Gordon S
Regulation of macrophage activation and HIV replication.
Advances in experimental medicine and biology 1995;374():47-56.
-
1994: de Villiers W J; Fraser I P; Gordon S
Cytokine and growth factor regulation of macrophage scavenger receptor expression and function.
Immunology letters 1994;43(1-2):73-9.
-
1994: Hughes D A; Fraser I P; Gordon S
Murine M phi scavenger receptor: adhesion function and expression.
Immunology letters 1994;43(1-2):7-14.
-
1994: Montaner L J; Griffin P; Gordon S
Interleukin-10 inhibits initial reverse transcription of human immunodeficiency virus type 1 and mediates a virostatic latent state in primary blood-derived human macrophages in vitro.
The Journal of general virology 1994;75 ( Pt 12)():3393-400.
-
1994: Crocker P R; Mucklow S; Bouckson V; McWilliam A; Willis A C; Gordon S; Milon G; Kelm S; Bradfield P
Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains.
The EMBO journal 1994;13(19):4490-503.
-
1994: Bell M D; Lopez-Gonzalez R; Lawson L; Hughes D; Fraser I; Gordon S; Perry V H
Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS.
Journal of neurocytology 1994;23(10):605-13.
-
1994: Montaner L J; Gordon S
Th2-mediated HIV1 virostatic state: macrophage-specific regulation in vitro.
Research in immunology 1994;145(8-9):583-7; discussion 587-8.
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1994: Gordon S; Keshav S; Stein M
BCG-induced granuloma formation in murine tissues.
Immunobiology 1994;191(4-5):369-77.
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1994: Fraser I; Doyle A; Hughes D; Gordon S
Use of surface molecules and receptors for studying macrophages and mononuclear phagocytes.
Journal of immunological methods 1994;174(1-2):95-102.
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1994: de Villiers W J; Fraser I P; Hughes D A; Doyle A G; Gordon S
Macrophage-colony-stimulating factor selectively enhances macrophage scavenger receptor expression and function.
The Journal of experimental medicine 1994;180(2):705-9.
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1994: Fraser I P; Gordon S
Murine erythroleukemia (MEL) cells bear ligands for the sialoadhesin and erythroblast receptor macrophage hemagglutinins.
European journal of cell biology 1994;64(2):217-21.
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1994: Collin M; Illei P; James W; Gordon S
Definition of the range and distribution of human immunodeficiency virus macrophage tropism using PCR-based infectivity measurements.
The Journal of general virology 1994;75 ( Pt 7)():1597-603.
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1994: Doyle A G; Herbein G; Montaner L J; Minty A J; Caput D; Ferrara P; Gordon S
Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gamma.
European journal of immunology 1994;24(6):1441-5.
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1994: Hopkinson-Woolley J; Hughes D; Gordon S; Martin P
Macrophage recruitment during limb development and wound healing in the embryonic and foetal mouse.
Journal of cell science 1994;107 ( Pt 5)():1159-67.
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1994: Collin M; Gordon S
The kinetics of human immunodeficiency virus reverse transcription are slower in primary human macrophages than in a lymphoid cell line.
Virology 1994;200(1):114-20.
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1994: Herbein G; Keshav S; Collin M; Montaner L J; Gordon S
HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection.
Clinical and experimental immunology 1994;95(3):442-9.
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1993: Lawson L J; Perry V H; Gordon S
Microglial responses to physiological change: osmotic stress elevates DNA synthesis of neurohypophyseal microglia.
Neuroscience 1993;56(4):929-38.
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1993: Reid D M; Perry V H; Andersson P B; Gordon S
Mitosis and apoptosis of microglia in vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier.
Neuroscience 1993;56(3):529-33.
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1993: Montaner L J; Doyle A G; Collin M; Herbein G; Illei P; James W; Minty A; Caput D; Ferrara P; Gordon S
Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro.
The Journal of experimental medicine 1993;178(2):743-7.
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1993: Fraser I; Hughes D; Gordon S
Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor.
Nature 1993;364(6435):343-6.
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1993: Perry V H; Andersson P B; Gordon S
Macrophages and inflammation in the central nervous system.
Trends in neurosciences 1993;16(7):268-73.
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1993: Holness C L; da Silva R P; Fawcett J; Gordon S; Simmons D L
Macrosialin, a mouse macrophage-restricted glycoprotein, is a member of the lamp/lgp family.
The Journal of biological chemistry 1993;268(13):9661-6.
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1993: Collin M; Herbein G; Montaner L; Gordon S
PCR analysis of HIV1 infection of macrophages: virus entry is CD4-dependent.
Research in virology 1993;144(1):13-9.
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1992: McWilliam A S; Tree P; Gordon S
Interleukin 4 regulates induction of sialoadhesin, the macrophage sialic acid-specific receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10522-6.
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1992: Matyszak M K; Lawson L J; Perry V H; Gordon S
Stromal macrophages of the choroid plexus situated at an interface between the brain and peripheral immune system constitutively express major histocompatibility class II antigens.
Journal of neuroimmunology 1992;40(2-3):173-81.
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1992: Stein M; Keshav S; Harris N; Gordon S
Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation.
The Journal of experimental medicine 1992;176(1):287-92.
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1992: Andersson P B; Perry V H; Gordon S
Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system.
The Journal of experimental medicine 1992;176(1):255-9.
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1992: Gordon S; Fraser I; Nath D; Hughes D; Clarke S
Macrophages in tissues and in vitro.
Current opinion in immunology 1992;4(1):25-32.
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1992: Rabinowitz S; Horstmann H; Gordon S; Griffiths G
Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages.
The Journal of cell biology 1992;116(1):95-112.
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1992: Perry V H; Crocker P R; Gordon S
The blood-brain barrier regulates the expression of a macrophage sialic acid-binding receptor on microglia.
Journal of cell science 1992;101 ( Pt 1)():201-7.
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1992: Lawson L J; Perry V H; Gordon S
Turnover of resident microglia in the normal adult mouse brain.
Neuroscience 1992;48(2):405-15.
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1992: Andersson P B; Perry V H; Gordon S
The acute inflammatory response to lipopolysaccharide in CNS parenchyma differs from that in other body tissues.
Neuroscience 1992;48(1):169-86.
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1992: Gordon S; Lawson L; Rabinowitz S; Crocker P R; Morris L; Perry V H
Antigen markers of macrophage differentiation in murine tissues.
Current topics in microbiology and immunology 1992;181():1-37.
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1991: Keshav S; Chung P; Milon G; Gordon S
Lysozyme is an inducible marker of macrophage activation in murine tissues as demonstrated by in situ hybridization.
The Journal of experimental medicine 1991;174(5):1049-58.
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1991: Rabinowitz S S; Gordon S
Macrosialin, a macrophage-restricted membrane sialoprotein differentially glycosylated in response to inflammatory stimuli.
The Journal of experimental medicine 1991;174(4):827-36.
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1991: Andersson P B; Perry V H; Gordon S
The CNS acute inflammatory response to excitotoxic neuronal cell death.
Immunology letters 1991;30(2):177-81.
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1991: Morris L; Crocker P R; Fraser I; Hill M; Gordon S
Expression of a divalent cation-dependent erythroblast adhesion receptor by stromal macrophages from murine bone marrow.
Journal of cell science 1991;99 ( Pt 1)():141-7.
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1991: Collin M; James W; Gordon S
Development of techniques to analyse the formation of HIV provirus in primary human macrophages.
Research in virology 1991;142(2-3):105-12.
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1991: Stein M; Gordon S
Regulation of tumor necrosis factor (TNF) release by murine peritoneal macrophages: role of cell stimulation and specific phagocytic plasma membrane receptors.
European journal of immunology 1991;21(2):431-7.
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1991: Crocker P R; Morris L; Gordon S
Adhesion receptors involved in the erythroblastic island.
Blood cells 1991;17(1):83-91; discussion 91-6.
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1991: Perry V H; Gordon S
Macrophages and the nervous system.
International review of cytology 1991;125():203-44.
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1991: Andersson P B; Perry V H; Gordon S
The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration.
Neuroscience 1991;42(1):201-14.
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1990: Keshav S; Chung L P; Gordon S
Macrophage products in inflammation.
Diagnostic microbiology and infectious disease 1990;13(5):439-47.
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1990: Calder P C; Bond J A; Harvey D J; Gordon S; Newsholme E A
Uptake and incorporation of saturated and unsaturated fatty acids into macrophage lipids and their effect upon macrophage adhesion and phagocytosis.
The Biochemical journal 1990;269(3):807-14.
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1990: Teppler H; Lee S H; Rieber E P; Gordon S
Murine immunoglobulin G anti-CD4 monoclonal antibodies bind to primary human monocytes and macrophages through Fc receptors as well as authentic CD4.
AIDS (London, England) 1990;4(7):627-32.
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1990: Rosen H; Gordon S
The role of the type 3 complement receptor in the induced recruitment of myelomonocytic cells to inflammatory sites in the mouse.
American journal of respiratory cell and molecular biology 1990;3(1):3-10.
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1990: Rosen H; Gordon S
Adoptive transfer of fluorescence-labeled cells shows that resident peritoneal macrophages are able to migrate into specialized lymphoid organs and inflammatory sites in the mouse.
European journal of immunology 1990;20(6):1251-8.
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1990: Keshav S; Lawson L; Chung L P; Stein M; Perry V H; Gordon S
Tumor necrosis factor mRNA localized to Paneth cells of normal murine intestinal epithelium by in situ hybridization.
The Journal of experimental medicine 1990;171(1):327-32.
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1990: Lawson L J; Perry V H; Dri P; Gordon S
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain.
Neuroscience 1990;39(1):151-70.
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1989: Rabinowitz S; Gordon S
Differential expression of membrane sialoglycoproteins in exudate and resident mouse peritoneal macrophages.
Journal of cell science 1989;93 ( Pt 4)():623-30.
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1989: Rosen H; Gordon S
Current status review: adhesion molecules and myelomonocytic cell-endothelial interactions.
British journal of experimental pathology 1989;70(3):385-94.
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1989: Crocker P R; Gordon S
Mouse macrophage hemagglutinin (sheep erythrocyte receptor) with specificity for sialylated glycoconjugates characterized by a monoclonal antibody.
The Journal of experimental medicine 1989;169(4):1333-46.
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1989: Rosen H; Milon G; Gordon S
Antibody to the murine type 3 complement receptor inhibits T lymphocyte-dependent recruitment of myelomonocytic cells in vivo.
The Journal of experimental medicine 1989;169(2):535-48.
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1989: Pow D V; Perry V H; Morris J F; Gordon S
Microglia in the neurohypophysis associate with and endocytose terminal portions of neurosecretory neurons.
Neuroscience 1989;33(3):567-78.
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1988: Crocker P R; Hill M; Gordon S
Regulation of a murine macrophage haemagglutinin (sheep erythrocyte receptor) by a species-restricted serum factor.
Immunology 1988;65(4):515-22.
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1988: Ripoche J; Mitchell J A; Erdei A; Madin C; Moffatt B; Mokoena T; Gordon S; Sim R B
Interferon gamma induces synthesis of complement alternative pathway proteins by human endothelial cells in culture.
The Journal of experimental medicine 1988;168(5):1917-22.
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1988: Chung L P; Keshav S; Gordon S
Cloning the human lysozyme cDNA: inverted Alu repeat in the mRNA and in situ hybridization for macrophages and Paneth cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6227-31.
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1988: Gordon S; Keshav S; Chung L P
Mononuclear phagocytes: tissue distribution and functional heterogeneity.
Current opinion in immunology 1988;1(1):26-35.
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1988: Lee S H; Crocker P R; Westaby S; Key N; Mason D Y; Gordon S; Weatherall D J
Isolation and immunocytochemical characterization of human bone marrow stromal macrophages in hemopoietic clusters.
The Journal of experimental medicine 1988;168(3):1193-8.
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1988: Morris L; Crocker P R; Gordon S
Murine fetal liver macrophages bind developing erythroblasts by a divalent cation-dependent hemagglutinin.
The Journal of cell biology 1988;106(3):649-56.
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1988: Crocker P R; Morris L; Gordon S
Novel cell surface adhesion receptors involved in interactions between stromal macrophages and haematopoietic cells.
Journal of cell science. Supplement 1988;9():185-206.
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1988: Gordon S; Perry V H; Rabinowitz S; Chung L P; Rosen H
Plasma membrane receptors of the mononuclear phagocyte system.
Journal of cell science. Supplement 1988;9():1-26.
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1987: Rosen H; Gordon S
Surface events in polymorphonuclear leucocyte activation: insights from a hydrophobic membrane antigen that triggers the respiratory burst.
Journal of cell science 1987;88 ( Pt 5)():591-601.
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1987: Rosen H; Gordon S
Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.
The Journal of experimental medicine 1987;166(6):1685-701.
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1987: Perry V H; Gordon S
Modulation of CD4 antigen on macrophages and microglia in rat brain.
The Journal of experimental medicine 1987;166(4):1138-43.
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