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Julia Gorelik

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TOP 3
Julia Gorelik; Alexander R Lyon; Peter T Wright; Sian E Harding
Spatial control of the βAR system in heart failure: the transverse tubule and beyond.
Michele Miragoli; Pavel Novak; Pakatip Ruenraroengsak; Andrew I Shevchuk; Teresa D Tetley; Yuri E Korchev; Max J Lab; Julia Gorelik
Functional interaction between charged nanoparticles and cardiac tissue: a new paradigm for cardiac arrhythmia?
Anamika Bhargava; Mario Delmar; Yuri Korchev; Xianming Lin; Kinneri Mehta; Pavel Novak; Julia Gorelik
Super-resolution scanning patch clamp reveals clustering of functional ion channels in adult ventricular myocyte.

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All Publications

2013: Julia Gorelik; Alexander R Lyon; Peter T Wright; Sian E Harding
Spatial control of the βAR system in heart failure: the transverse tubule and beyond.
Cardiovascular research 2013;98(2):216-24.
2013: Michele Miragoli; Pavel Novak; Pakatip Ruenraroengsak; Andrew I Shevchuk; Teresa D Tetley; Yuri E Korchev; Max J Lab; Julia Gorelik
Functional interaction between charged nanoparticles and cardiac tissue: a new paradigm for cardiac arrhythmia?
Nanomedicine (London, England) 2013;8(5):725-37.
2013: Anamika Bhargava; Mario Delmar; Yuri Korchev; Xianming Lin; Kinneri Mehta; Pavel Novak; Julia Gorelik
Super-resolution scanning patch clamp reveals clustering of functional ion channels in adult ventricular myocyte.
Circulation research 2013;112(8):1112-20.
2013: Michael Ibrahim; Ralph Knöll; Alexey Moshkov; Christopher Rao; Michael Schneider; Urszula Siedlecka; Anamika Bhargava; Byambajav Buyandelger; Julia Gorelik; Mutsuo Harada; Magdi H Yacoub; Cesare M N Terracciano
A critical role for Telethonin in regulating t-tubule structure and function in the mammalian heart.
Human molecular genetics 2013;22(2):372-83.
2013: Anamika Bhargava; Julia Gorelik
Recording single-channel currents using "smart patch-clamp" technique.
Methods in molecular biology (Clifton, N.J.) 2013;998():189-97.
2013: Max J Lab; Peter T Wright; Anamika Bhargava; Julia Gorelik
The scanning ion conductance microscope for cellular physiology.
American journal of physiology. Heart and circulatory physiology 2013;304(1):H1-11.
2012: Michael Ibrahim; Punam Kukadia; Manoraj Navaratnarajah; Urszula Siedlecka; Sergiy Tokar; Victor T Tsang; Carin van Doorn; Magdi H Yacoub; James E Cartledge; Julia Gorelik; Cesare M N Terracciano
Cardiomyocyte Ca2+ handling and structure is regulated by degree and duration of mechanical load variation.
Journal of cellular and molecular medicine 2012;16(12):2910-8.
2012: Helen Paur; Nicholas S Peters; Mario Petrou; Markus B Sikkel; Daniel J Stuckey; Hong Sun; Matthew H Tranter; Peter T Wright; Zhaolun Zheng; Ivan A Diakonov; Haibin Gong; Julia Gorelik; Alexander R Lyon; Catherine Mansfield; Viacheslav O Nikolaev; Peter O'Gara; Laura Pannell; Sian E Harding
High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy.
Circulation 2012;126(6):697-706.
2012: Yasufumi Takahashi; Patrick R Unwin; Pavel Novak; Andrew I Shevchuk; Hitoshi Shiku; Babak Babakinejad; Julia Gorelik; David Klenerman; Yuri E Korchev; Julie Macpherson; Tomokazu Matsue
Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(29):11540-5.
2012: Michael Ibrahim; Alexey V Moshkov; Manoraj Navaratnarajah; Christopher Rao; Urszula Siedlecka; Priyanthi Dias; Julia Gorelik; Magdi H Yacoub; Cesare M Terracciano
Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca(2+)-induced Ca(2+)release in a rodent model of heart failure.
European journal of heart failure 2012;14(6):571-80.
2012: Andrew I Shevchuk; Marcus Taylor; Azza Ziyadeh-Isleem; Max J Lab; Christien J Merrifield; Pavel Novak; Marc Bitoun; Ivan A Diakonov; Julia Gorelik; Pascale Guicheney; David Klenerman; Yuri E Korchev
An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy.
The Journal of cell biology 2012;197(4):499-508.
2012: Alexander R Lyon; Kenneth T MacLeod; Michele Miragoli; Viacheslav O Nikolaev; Helen Paur; Nicholas S Peters; Markus B Sikkel; Roger J Hajjar; Sian E Harding; Jean-Sebastien Hulot; Erik Kohlbrenner; Yuri E Korchev; Ludovic Benard; Julia Gorelik
Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure.
Circulation. Heart failure 2012;5(3):357-65.
2012: Pakatip Ruenraroengsak; Andrew Thorley; Eugenia Valsami-Jones; Deborah Berhanu; Julia Gorelik; Yuri E Korchev; Pavel Novak; Teresa D Tetley
Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles.
Nanotoxicology 2012;6(1):94-108.
2012: Claire M F Potter; Sophie Schobesberger; Peter D Weinberg; Martina H Lundberg; Jane A Mitchell; Julia Gorelik
Shape and compliance of endothelial cells after shear stress in vitro or from different aortic regions: scanning ion conductance microscopy study.
PloS one 2012;7(2):e31228.
2011: Michele Miragoli; Alexey Moshkov; Viacheslav O Nikolaev; Stephan Rohr; Nicoló Salvarani; Mary N Sheppard; Matilda Virta; Sarah Wells; Catherine Williamson; William M Hague; Siti H Sheikh Abdul Kadir; Max J Lab; Julia Gorelik
A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart.
Hepatology (Baltimore, Md.) 2011;54(4):1282-92.
2011: Michael Ibrahim; Julia Gorelik; Magdi H Yacoub; Cesare M N Terracciano
The structure and function of cardiac t-tubules in health and disease.
Proceedings. Biological sciences / The Royal Society 2011;278(1719):2714-23.
2011: Michele Miragoli; Alexey Moshkov; Pavel Novak; Andrew I Shevchuk; Viacheslav O Nikolaev; Ismail El-Hamamsy; Claire M F Potter; Peter Wright; S H Sheikh Abdul Kadir; Alexander R Lyon; Jane A Mitchell; Adrian H Chester; David Klenerman; Max J Lab; Yuri E Korchev; Sian E Harding; Julia Gorelik
Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells.
Journal of the Royal Society, Interface / the Royal Society 2011;8(60):913-25.
2011: Andrew I Shevchuk; Pavel Novak; Yasufumi Takahashi; Richard Clarke; Michele Miragoli; Babak Babakinejad; Julia Gorelik; Yuri E Korchev; David Klenerman
Realizing the biological and biomedical potential of nanoscale imaging using a pipette probe.
Nanomedicine (London, England) 2011;6(3):565-75.
2011: Claire M F Potter; Martina H Lundberg; Louise S Harrington; Christina M Warboys; Timothy D Warner; R Eric Berson; Alexey V Moshkov; Julia Gorelik; Peter D Weinberg; Jane A Mitchell
Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(2):384-91.
2011: Gábor Földes; Maxime Mioulane; Jamie S Wright; Alexander Q Liu; Pavel Novak; Béla Merkely; Julia Gorelik; Michael D Schneider; Nadire N Ali; Sian E Harding
Modulation of human embryonic stem cell-derived cardiomyocyte growth: a testbed for studying human cardiac hypertrophy?
Journal of molecular and cellular cardiology 2011;50(2):367-76.
2011: Catherine Williamson; Shadi Abu-Hayyeh; Victoria Geenes; Michele Miragoli; Georgia Papacleovoulou; Siti Sheikh Abdul Kadir; Julia Gorelik
Bile acid signaling in fetal tissues: implications for intrahepatic cholestasis of pregnancy.
Digestive diseases (Basel, Switzerland) 2011;29(1):58-61.
2010: Viacheslav O Nikolaev; Alexey Moshkov; Alexander R Lyon; Michele Miragoli; Pavel Novak; Helen Paur; Martin J Lohse; Yuri E Korchev; Sian E Harding; Julia Gorelik
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
Science (New York, N.Y.) 2010;327(5973):1653-7.
2010: Siti H Sheikh Abdul Kadir; Michele Miragoli; Shadi Abu-Hayyeh; Alexey V Moshkov; Qilian Xie; Verena Keitel; Viacheslav O Nikolaev; Catherine Williamson; Julia Gorelik
Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes.
PloS one 2010;5(3):e9689.
2009: Siti H Sheikh Abdul Kadir; Nadire N Ali; Maxime Mioulane; Marta Brito-Martins; Shadi Abu-Hayyeh; Gabor Foldes; Alexey V Moshkov; Catherine Williamson; Sian E Harding; Julia Gorelik
Embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease.
Journal of cellular and molecular medicine 2009;13(9B):3730-41.
2009: Alexander R Lyon; Kenneth T MacLeod; Yanjun Zhang; Edwin Garcia; Gaelle Kikonda Kanda; Max J Lab; Yuri E Korchev; Sian E Harding; Julia Gorelik
Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(16):6854-9.
2009: Pavel Novak; Chao Li; Andrew I Shevchuk; Ruben Stepanyan; Matthew Caldwell; Simon Hughes; Trevor G Smart; Julia Gorelik; Victor P Ostanin; Max J Lab; Guy W J Moss; Gregory I Frolenkov; David Klenerman; Yuri E Korchev
Nanoscale live-cell imaging using hopping probe ion conductance microscopy.
Nature methods 2009;6(4):279-81.
2008: Julia Gorelik; Nadire N Ali; Siti H Sheikh Abdul Kadir; Max Lab; Petra Stojkovic; Lyle Armstrong; Elena V Sviderskaya; Yuri A Negulyaev; David Klenerman; Dorothy C Bennett; Majlinda Lako; Sian E Harding; Miodrag Stojkovic; Yuri E Korchev
Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective.
Tissue engineering. Part C, Methods 2008;14(4):311-8.
2008: Sarah J Kemp; Andrew Thorley; Julia Gorelik; Michael J Seckl; Michael J O'Hare; Alexandre Arcaro; Yuri E Korchev; Peter Goldstraw; Teresa D Tetley
Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake.
American journal of respiratory cell and molecular biology 2008;39(5):591-7.
2008: Daniel Paulo Sánchez Herrera; Nick Johnson; Chao Li; Pavel Novak; Johannes Rheinlaender; Yanjun Zhang; Uma Anand; Praveen Anand; Julia Gorelik; Gregory I Frolenkov; Christopher Benham; Max J Lab; Victor P Ostanin; Tilman E Schäffer; David Klenerman; Yuri E Korchev
Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette.
Biophysical journal 2008;95(6):3017-27.
2007: Yanjun Zhang; Daniel Paulo Sánchez Herrera; Julia Gorelik; David Klenerman; Max J Lab; Christopher Edwards; Yuri E Korchev
Basolateral P2X4-like receptors regulate the extracellular ATP-stimulated epithelial Na+ channel activity in renal epithelia.
American journal of physiology. Renal physiology 2007;292(6):F1734-40.
2007: Sian E Harding; Nadire N Ali; Marta Brito-Martins; Julia Gorelik
The human embryonic stem cell-derived cardiomyocyte as a pharmacological model.
Pharmacology & therapeutics 2007;113(2):341-53.
2007: Daniel Paulo Sánchez Herrera; Uma Anand; Julia Gorelik; Christopher D Benham; Chas Bountra; Max J Lab; David Klenerman; Rolfe Birch; Praveen Anand; Yuri E Korchev
Localized and non-contact mechanical stimulation of dorsal root ganglion sensory neurons using scanning ion conductance microscopy.
Journal of neuroscience methods 2007;159(1):26-34.
2006: Julia Gorelik; Lin Q Yang; Yanjun Zhang; Max J Lab; Yuri E Korchev; Sian E Harding
A novel Z-groove index characterizing myocardial surface structure.
Cardiovascular research 2006;72(3):422-9.
2006: Julia Gorelik; P Patel; C Ng'andwe; Igor Vodyanoy; Ivan A Diakonov; Max J Lab; Yuri E Korchev; Catherine Williamson
Genes encoding bile acid, phospholipid and anion transporters are expressed in a human fetal cardiomyocyte culture.
BJOG : an international journal of obstetrics and gynaecology 2006;113(5):552-8.
2006: Julia Gorelik; Nadire N Ali; Andrew I Shevchuk; Max J Lab; Catherine Williamson; Sian E Harding; Yuri E Korchev
Functional characterization of embryonic stem cell-derived cardiomyocytes using scanning ion conductance microscopy.
Tissue engineering 2006;12(4):657-64.
2005: Julia Gorelik; Yanjun Zhang; Daniel Paulo Sánchez Herrera; Andrew I Shevchuk; Gregory I Frolenkov; Max J Lab; David Klenerman; Christopher Edwards; Yuri E Korchev
Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):15000-5.
2005: Yanjun Zhang; Julia Gorelik; Daniel Paulo Sánchez Herrera; Andrew I Shevchuk; Max J Lab; Igor Vodyanoy; David Klenerman; Christopher Edwards; Yuri E Korchev
Scanning ion conductance microscopy reveals how a functional renal epithelial monolayer maintains its integrity.
Kidney international 2005;68(3):1071-7.
2005: Liming Ying; Andreas Bruckbauer; Dejian Zhou; Julia Gorelik; Andrew I Shevchuk; Max J Lab; Yuri E Korchev; David Klenerman
The scanned nanopipette: a new tool for high resolution bioimaging and controlled deposition of biomolecules.
Physical chemistry chemical physics : PCCP 2005;7(15):2859-66.
2004: Julia Gorelik; Andrew I Shevchuk; Michael de Swiet; Max J Lab; Yuri E Korchev; Catherine Williamson
Comparison of the arrhythmogenic effects of tauro- and glycoconjugates of cholic acid in an in vitro study of rat cardiomyocytes.
BJOG : an international journal of obstetrics and gynaecology 2004;111(8):867-70.
2004: Julia Gorelik; Yanjun Zhang; Andrew I Shevchuk; Gregory I Frolenkov; Daniel Paulo Sánchez Herrera; Max J Lab; Igor Vodyanoy; Christopher R W Edwards; David Klenerman; Yuri E Korchev
The use of scanning ion conductance microscopy to image A6 cells.
Molecular and cellular endocrinology 2004;217(1-2):101-8.
2004: Alberto Darszon; Christopher D Wood; Carmen Beltrán; Daniel Paulo Sánchez Herrera; Esmeralda Rodríguez; Julia Gorelik; Yuri E Korchev; Takuya Nishigaki
Measuring ion fluxes in sperm.
Methods in cell biology 2004;74():545-76.
2003: Julia Gorelik; Igor Vodyanoy; Andrew I Shevchuk; Ivan A Diakonov; Max J Lab; Yuri E Korchev
Esmolol is antiarrhythmic in doxorubicin-induced arrhythmia in cultured cardiomyocytes - determination by novel rapid cardiomyocyte assay.
FEBS letters 2003;548(1-3):74-8.
2003: Julia Gorelik; Andrew I Shevchuk; Gregory I Frolenkov; Ivan A Diakonov; Max J Lab; Corné J Kros; Guy P Richardson; Igor Vodyanoy; Christopher R W Edwards; David Klenerman; Yuri E Korchev
Dynamic assembly of surface structures in living cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5819-22.
2003: Julia Gorelik; Andrew I Shevchuk; Ivan A Diakonov; Michael de Swiet; Max J Lab; Yuri E Korchev; Catherine Williamson
Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes.
BJOG : an international journal of obstetrics and gynaecology 2003;110(5):467-74.
2003: Alison M Rothery; Julia Gorelik; Andreas Bruckbauer; W Yu; Yuri E Korchev; David Klenerman
A novel light source for SICM-SNOM of living cells.
Journal of microscopy 2003;209(Pt 2):94-101.
2002: Julia Gorelik; Andrew I Shevchuk; Michal Ramalho; M Elliott; C Lei; C F Higgins; Max J Lab; David Klenerman; Nina Krauzewicz; Yuri E Korchev
Scanning surface confocal microscopy for simultaneous topographical and fluorescence imaging: application to single virus-like particle entry into a cell.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16018-23.
2002: Julia Gorelik; Yuchun Gu; Hilmar A Spohr; Andrew I Shevchuk; Max J Lab; Sian E Harding; Christopher R W Edwards; Michael Whitaker; Guy W J Moss; David C H Benton; Daniel Paulo Sánchez Herrera; Alberto Darszon; Igor Vodyanoy; David Klenerman; Yuri E Korchev
Ion channels in small cells and subcellular structures can be studied with a smart patch-clamp system.
Biophysical journal 2002;83(6):3296-303.
2002: Julia Gorelik; Sian E Harding; Andrew I Shevchuk; Duleepa Koralage; Max J Lab; Michael de Swiet; Yuri E Korchev; Catherine Williamson
Taurocholate induces changes in rat cardiomyocyte contraction and calcium dynamics.
Clinical science (London, England : 1979) 2002;103(2):191-200.
2002: Yuchun Gu; Julia Gorelik; Hilmar A Spohr; Andrew I Shevchuk; Max J Lab; Sian E Harding; Igor Vodyanoy; David Klenerman; Yuri E Korchev
High-resolution scanning patch-clamp: new insights into cell function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):748-50.
2001: Andrew I Shevchuk; Julia Gorelik; Sian E Harding; Max J Lab; David Klenerman; Yuri E Korchev
Simultaneous measurement of Ca2+ and cellular dynamics: combined scanning ion conductance and optical microscopy to study contracting cardiac myocytes.
Biophysical journal 2001;81(3):1759-64.
2001: Catherine Williamson; Julia Gorelik; B M Eaton; Max J Lab; Michael de Swiet; Yuri E Korchev
The bile acid taurocholate impairs rat cardiomyocyte function: a proposed mechanism for intra-uterine fetal death in obstetric cholestasis.
Clinical science (London, England : 1979) 2001;100(4):363-9.
2001: Julia Gorelik; OA Cherepanova; Irina Voronkina; I A Diakonov; Miralda I Blinova; George Pinaev
Laminin-2/4 from human placenta is a better adhesion agent for primary keratinocytes than laminin-1 from EHS sarcoma.
Cell biology international 2001;25(5):395-402.
2000: Yuri E Korchev; M Raval; Max J Lab; Julia Gorelik; Christopher R W Edwards; Trevor Rayment; David Klenerman
Hybrid scanning ion conductance and scanning near-field optical microscopy for the study of living cells.
Biophysical journal 2000;78(5):2675-9.
2000: Yuri E Korchev; Julia Gorelik; Max J Lab; Elena V Sviderskaya; CL Johnston; C R Coombes; Igor Vodyanoy; Christopher R W Edwards
Cell volume measurement using scanning ion conductance microscopy.
Biophysical journal 2000;78(1):451-7.