Gregory Gores

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Cazanave Sophie C; Mott Justin L; Elmi Nafisa A; Bronk Steven F; Werneburg Nathan W; Akazawa Yuko; Kahraman Alisan; Garrison Sean P; Zambetti Gerard P; Charlton Michael R; Gores Gregory J
JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis.
Kahraman Alisan; Mott Justin L; Bronk Steven F; Werneburg Nathan W; Barreyro Fernando J; Guicciardi Maria E; Akazawa Yuko; Braley Karen; Craig Ruth W; Gores Gregory J
Overexpression of mcl-1 attenuates liver injury and fibrosis in the bile duct-ligated mouse.
Beraza Naiara; Malato Yann; Sander Leif E; Al-Masaoudi Malika; Freimuth Julia; Riethmacher Dieter; Gores Gregory J; Roskams Tania; Liedtke Christian; Trautwein Christian
Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage.

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2009: Cazanave Sophie C; Mott Justin L; Elmi Nafisa A; Bronk Steven F; Werneburg Nathan W; Akazawa Yuko; Kahraman Alisan; Garrison Sean P; Zambetti Gerard P; Charlton Michael R; Gores Gregory J
JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis.
The Journal of biological chemistry 2009;284(39):26591-602.
2009: Kahraman Alisan; Mott Justin L; Bronk Steven F; Werneburg Nathan W; Barreyro Fernando J; Guicciardi Maria E; Akazawa Yuko; Braley Karen; Craig Ruth W; Gores Gregory J
Overexpression of mcl-1 attenuates liver injury and fibrosis in the bile duct-ligated mouse.
Digestive diseases and sciences 2009;54(9):1908-17.
2009: Beraza Naiara; Malato Yann; Sander Leif E; Al-Masaoudi Malika; Freimuth Julia; Riethmacher Dieter; Gores Gregory J; Roskams Tania; Liedtke Christian; Trautwein Christian
Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage.
The Journal of experimental medicine 2009;206(8):1727-37.
2009: Masuoka Howard C; Guicciardi Maria Eugenia; Gores Gregory J
Caspase inhibitors for the treatment of hepatitis C.
Clinics in liver disease 2009;13(3):467-75.
2009: Kahraman Alisan; Bronk Steven F; Cazanave Sophie; Werneburg Nathan W; Mott Justin L; Contreras Patricia C; Gores Gregory J
Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(8):805-13.
2009: Gores Gregory J
Hepatology: a home for hepatocellular cancer publications.
Hepatology (Baltimore, Md.) 2009;50(1):1-2.
2009: Akazawa Yuko; Mott Justin L; Bronk Steven F; Werneburg Nathan W; Kahraman Alisan; Guicciardi Maria Eugenia; Meng Xue Wei; Kohno Shigeru; Shah Vijay H; Kaufmann Scott H; McNiven Mark A; Gores Gregory J
Death receptor 5 internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines.
Gastroenterology 2009;136(7):2365-2376.e1-7.
2009: Fritcher Emily G Barr; Kipp Benjamin R; Halling Kevin C; Oberg Trynda N; Bryant Sandra C; Tarrell Robert F; Gores Gregory J; Levy Michael J; Clayton Amy C; Sebo Thomas J; Roberts Lewis R
A multivariable model using advanced cytologic methods for the evaluation of indeterminate pancreatobiliary strictures.
Gastroenterology 2009;136(7):2180-6.
2009: Guicciardi Maria Eugenia; Gores Gregory J
Life and death by death receptors.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(6):1625-37.
2009: Selaru Florin M; Olaru Alexandru V; Kan Takatsugu; David Stefan; Cheng Yulan; Mori Yuriko; Yang Jian; Paun Bogdan; Jin Zhe; Agarwal Rachana; Hamilton James P; Abraham John; Georgiades Christos; Alvarez Hector; Vivekanandan Perumal; Yu Wayne; Maitra Anirban; Torbenson Michael; Thuluvath Paul J; Gores Gregory J; LaRusso Nicholas F; Hruban Ralph; Meltzer Stephen J
MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.
Hepatology (Baltimore, Md.) 2009;49(5):1595-601.
2009: Rea David J; Rosen Charles B; Nagorney David M; Heimbach Julie K; Gores Gregory J
Transplantation for cholangiocarcinoma: when and for whom?
Surgical oncology clinics of North America 2009;18(2):325-37, ix.
2009: Lleo Ana; Selmi Carlo; Invernizzi Pietro; Podda Mauro; Coppel Ross L; Mackay Ian R; Gores Gregory J; Ansari Aftab A; Van de Water Judy; Gershwin M Eric
Apotopes and the biliary specificity of primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2009;49(3):871-9.
2009: O'Hara Steven P; Mott Justin L; Splinter Patrick L; Gores Gregory J; LaRusso Nicholas F
MicroRNAs: key modulators of posttranscriptional gene expression.
Gastroenterology 2009;136(1):17-25.
2008: Sirica Alphonse E; Nathanson Michael H; Gores Gregory J; Larusso Nicholas F
Pathobiology of biliary epithelia and cholangiocarcinoma: proceedings of the Henry M. and Lillian Stratton Basic Research Single-Topic Conference.
Hepatology (Baltimore, Md.) 2008;48(6):2040-6.
2008: Malhi Harmeet; Gores Gregory J
Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease.
Seminars in liver disease 2008;28(4):360-9.
2008: Mott Justin L; Bronk Steve F; Mesa Ruben A; Kaufmann Scott H; Gores Gregory J
BH3-only protein mimetic obatoclax sensitizes cholangiocarcinoma cells to Apo2L/TRAIL-induced apoptosis.
Molecular cancer therapeutics 2008;7(8):2339-47.
2008: Rustgi Vinod K; Davis Gary L; Herrine Steven K; McCullough Arthur J; Friedman Scott L; Gores Gregory J
Future trends in hepatology: challenges and opportunities.
Hepatology (Baltimore, Md.) 2008;48(2):655-61.
2008: Blechacz Boris; Gores Gregory J
Tumor-specific marker genes for intrahepatic cholangiocarcinoma: utility and mechanistic insight.
Journal of hepatology 2008;49(2):160-2.
2008: Blechacz Boris; Gores Gregory J
Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment.
Hepatology (Baltimore, Md.) 2008;48(1):308-21.
2008: Langer Daniel A; Das Amitava; Semela David; Kang-Decker Ningling; Hendrickson Helen; Bronk Steven F; Katusic Zvonimir S; Gores Gregory J; Shah Vijay H
Nitric oxide promotes caspase-independent hepatic stellate cell apoptosis through the generation of reactive oxygen species.
Hepatology (Baltimore, Md.) 2008;47(6):1983-93.
2008: Llovet Josep M; Di Bisceglie Adrian M; Bruix Jordi; Kramer Barnett S; Lencioni Riccardo; Zhu Andrew X; Sherman Morris; Schwartz Myron; Lotze Michael; Talwalkar Jayant; Gores Gregory J;
Design and endpoints of clinical trials in hepatocellular carcinoma.
Journal of the National Cancer Institute 2008;100(10):698-711.
2008: Levy Michael J; Baron Todd H; Clayton Amy C; Enders Felicity B; Gostout Christopher J; Halling Kevin C; Kipp Benjamin R; Petersen Bret T; Roberts Lewis R; Rumalla Ashwin; Sebo Thomas J; Topazian Mark D; Wiersema Maurits J; Gores Gregory J
Prospective evaluation of advanced molecular markers and imaging techniques in patients with indeterminate bile duct strictures.
The American journal of gastroenterology 2008;103(5):1263-73.
2008: Malhi Harmeet; Gores Gregory J
Cellular and molecular mechanisms of liver injury.
Gastroenterology 2008;134(6):1641-54.
2008: Gores Gregory J
A strategic vision to promote advances in biliary tract disorders.
Current opinion in gastroenterology 2008;24(3):346-8.
2008: Li ZhengZheng; Berk Michael; McIntyre Thomas M; Gores Gregory J; Feldstein Ariel E
The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity.
Hepatology (Baltimore, Md.) 2008;47(5):1495-503.
2008: Kahraman Alisan; Barreyro Fernando J; Bronk Steven F; Werneburg Nathan W; Mott Justin L; Akazawa Yuko; Masuoka Howard C; Howe Charles L; Gores Gregory J
TRAIL mediates liver injury by the innate immune system in the bile duct-ligated mouse.
Hepatology (Baltimore, Md.) 2008;47(4):1317-30.
2008: Gleeson Ferga C; Rajan Elizabeth; Levy Michael J; Clain Jonathan E; Topazian Mark D; Harewood Gavin C; Papachristou Georgios I; Takahashi Naoki; Rosen Charles B; Gores Gregory J
EUS-guided FNA of regional lymph nodes in patients with unresectable hilar cholangiocarcinoma.
Gastrointestinal endoscopy 2008;67(3):438-43.
2008: Blechacz Boris R A; Gores Gregory J
Cholangiocarcinoma.
Clinics in liver disease 2008;12(1):131-50, ix.
2008: Gores Gregory J
The emergence of a new discipline, hepatobiliary oncology.
Hepatology (Baltimore, Md.) 2008;47(2):365-6.
2008: Rosen C B; Heimbach J K; Gores G J
Surgery for cholangiocarcinoma: the role of liver transplantation.
HPB : the official journal of the International Hepato Pancreato Biliary Association 2008;10(3):186-9.
2008: Guicciardi M Eugenia; Gores Gregory J
Cell stress gives a red light to the mitochondrial cell death pathway.
Science signaling 2008;1(7):pe9.
2007: Akazawa Yuko; Gores Gregory J
Death receptor-mediated liver injury.
Seminars in liver disease 2007;27(4):327-38.
2007: Baskin-Bey Edwina-S; Anan Akira; Isomoto Hajime; Bronk Steven-F; Gores Gregory-J
Constitutive androstane receptor agonist, TCPOBOP, attenuates steatohepatitis in the methionine choline-deficient diet-fed mouse.
World journal of gastroenterology : WJG 2007;13(42):5635-41.
2007: Mott Justin L; Gores Gregory J
Targeting IL-6 in cholangiocarcinoma therapy.
The American journal of gastroenterology 2007;102(10):2171-2.
2007: Gores Gregory J; Nagorney David M; Rosen Charles B
Cholangiocarcinoma: is transplantation an option? For whom?
Journal of hepatology 2007;47(4):455-9.
2007: Mantel Hendrik T J; Rosen Charles B; Heimbach Julie K; Nyberg Scott L; Ishitani Michael B; Andrews James C; McKusick Michael A; Haddock Michael G; Alberts Steven R; Gores Gregory J
Vascular complications after orthotopic liver transplantation after neoadjuvant therapy for hilar cholangiocarcinoma.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007;13(10):1372-81.
2007: Levy Michael J; Clain Jonathan E; Clayton Amy; Halling Kevin C; Kipp Benjamin R; Rajan Elizabeth; Roberts Lewis R; Root Renee M; Sebo Thomas J; Topazian Mark D; Wang Kenneth K; Wiersema Maurits J; Gores Gregory J
Preliminary experience comparing routine cytology results with the composite results of digital image analysis and fluorescence in situ hybridization in patients undergoing EUS-guided FNA.
Gastrointestinal endoscopy 2007;66(3):483-90.
2007: Werneburg Nathan W; Guicciardi M Eugenia; Bronk Steve F; Kaufmann Scott H; Gores Gregory J
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.
The Journal of biological chemistry 2007;282(39):28960-70.
2007: Mott Justin L; Gores Gregory J
Piercing the armor of hepatobiliary cancer: Bcl-2 homology domain 3 (BH3) mimetics and cell death.
Hepatology (Baltimore, Md.) 2007;46(3):906-11.
2007: Barreyro Fernando J; Kobayashi Shogo; Bronk Steven F; Werneburg Nathan W; Malhi Harmeet; Gores Gregory J
Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis.
The Journal of biological chemistry 2007;282(37):27141-54.
2007: Mott J L; Kobayashi S; Bronk S F; Gores G J
mir-29 regulates Mcl-1 protein expression and apoptosis.
Oncogene 2007;26(42):6133-40.
2007: Barr Fritcher Emily G; Kipp Benjamin R; Slezak Jeffrey M; Moreno-Luna Laura E; Gores Gregory J; Levy Michael J; Roberts Lewis R; Halling Kevin C; Sebo Thomas J
Correlating routine cytology, quantitative nuclear morphometry by digital image analysis, and genetic alterations by fluorescence in situ hybridization to assess the sensitivity of cytology for detecting pancreatobiliary tract malignancy.
American journal of clinical pathology 2007;128(2):272-9.
2007: Malhi Harmeet; Barreyro Fernando J; Isomoto Hajime; Bronk Steven F; Gores Gregory J
Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity.
Gut 2007;56(8):1124-31.
2007: Kobayashi Shogo; Lee Sun-Hee; Meng Xue W; Mott Justin L; Bronk Steven F; Werneburg Nathan W; Craig Ruth W; Kaufmann Scott H; Gores Gregory J
Serine 64 phosphorylation enhances the antiapoptotic function of Mcl-1.
The Journal of biological chemistry 2007;282(25):18407-17.
2007: Alberts Steven R; Gores Gregory J; Kim George P; Roberts Lewis R; Kendrick Michael L; Rosen Charles B; Chari Suresh T; Martenson James A
Treatment options for hepatobiliary and pancreatic cancer.
Mayo Clinic proceedings. Mayo Clinic 2007;82(5):628-37.
2007: Lazaridis Konstantinos N; Gores Gregory J
Our new president--Nicholas F. LaRusso, MD.
Gastroenterology 2007;132(5):2005-11.
2007: Oxentenko Amy S; Pardi Darrell S; Schmoll Jeffrey A; Gores Gregory J
Factors predicting initial career choices in gastroenterology fellows.
Journal of clinical gastroenterology 2007;41(5):445-50.
2007: Guicciardi Maria Eugenia; Bronk Steven F; Werneburg Nathan W; Gores Gregory J
cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(5):G1337-46.
2007: Leerapun Apinya; Suravarapu Sri V; Bida John P; Clark Raynell J; Sanders Elizabeth L; Mettler Teresa A; Stadheim Linda M; Aderca Ileana; Moser Catherine D; Nagorney David M; LaRusso Nicholas F; de Groen Piet C; Menon K V Narayanan; Lazaridis Konstantinos N; Gores Gregory J; Charlton Michael R; Roberts Rosebud O; Therneau Terry M; Katzmann Jerry A; Roberts Lewis R
The utility of Lens culinaris agglutinin-reactive alpha-fetoprotein in the diagnosis of hepatocellular carcinoma: evaluation in a United States referral population.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007;5(3):394-402; quiz 267.
2007: Georgiev Panco; Clavien Pierre A; Gores Gregory J
Liver graft protection by antiapoptotic drugs: a step further.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2007;13(3):318-20.
2007: Ustundag Yucel; Bronk Steven F; Gores Gregory J
Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells.
World journal of gastroenterology : WJG 2007;13(6):851-7.
2007: O'Hara Steven P; Small Aaron J; Nelson Jeremy B; Badley Andrew D; Chen Xian-Ming; Gores Gregory J; Larusso Nicholas F
The human immunodeficiency virus type 1 tat protein enhances Cryptosporidium parvum-induced apoptosis in cholangiocytes via a Fas ligand-dependent mechanism.
Infection and immunity 2007;75(2):684-96.
2007: Mott Justin L; Gores Gregory J
Predisposed to toxins: association of gallbladder cancer with N-acetyl transferase SNPs.
Cancer biology & therapy 2007;6(1):97-8.
2007: Isomoto Hajime; Mott Justin L; Kobayashi Shogo; Werneburg Nathan W; Bronk Steve F; Haan Serge; Gores Gregory J
Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing.
Gastroenterology 2007;132(1):384-96.
2007: Baskin-Bey E S; Washburn K; Feng S; Oltersdorf T; Shapiro D; Huyghe Mira; Burgart L; Garrity-Park M; van Vilsteren F G I; Oliver L K; Rosen C B; Gores G J
Clinical Trial of the Pan-Caspase Inhibitor, IDN-6556, in Human Liver Preservation Injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(1):218-25.
2006: Allina Jorge; Hu Bin; Sullivan Daniel M; Fiel Maria Isabel; Thung Swan N; Bronk Steven F; Huebert Robert C; van de Water Judy; LaRusso Nicholas F; Gershwin M E; Gores Gregory J; Odin Joseph A
T cell targeting and phagocytosis of apoptotic biliary epithelial cells in primary biliary cirrhosis.
Journal of autoimmunity 2006;27(4):232-41.
2006: Heimbach Julie K; Gores Gregory J; Haddock Michael G; Alberts Steven R; Pedersen Rachel; Kremers Walter; Nyberg Scott L; Ishitani Michael B; Rosen Charles B
Predictors of disease recurrence following neoadjuvant chemoradiotherapy and liver transplantation for unresectable perihilar cholangiocarcinoma.
Transplantation 2006;82(12):1703-7.
2006: Malhi Harmeet; Gores Gregory J
Cholangiocarcinoma: modern advances in understanding a deadly old disease.
Journal of hepatology 2006;45(6):856-67.
2006: Gwak G-Y; Yoon J-H; Lee S-H; Lee S-M; Lee H-S; Gores G J
Lysophosphatidylcholine suppresses apoptotic cell death by inducing cyclooxygenase-2 expression via a Raf-1 dependent mechanism in human cholangiocytes.
Journal of cancer research and clinical oncology 2006;132(12):771-9.
2006: Moreno Luna Laura E; Gores Gregory J
Advances in the diagnosis of cholangiocarcinoma in patients with primary sclerosing cholangitis.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006;12(11 Suppl 2):S15-9.
2006: Malhi H; Gores G J
TRAIL resistance results in cancer progression: a TRAIL to perdition?
Oncogene 2006;25(56):7333-5.
2006: Moreno Luna Laura E; Kipp Benjamin; Halling Kevin C; Sebo Thomas J; Kremers Walter K; Roberts Lewis R; Barr Fritcher Emily G; Levy Michael J; Gores Gregory J
Advanced cytologic techniques for the detection of malignant pancreatobiliary strictures.
Gastroenterology 2006;131(4):1064-72.
2006: Anan Akira; Baskin-Bey Edwina S; Isomoto Hajime; Mott Justin L; Bronk Steven F; Albrecht Jeffrey H; Gores Gregory J
Proteasome inhibition attenuates hepatic injury in the bile duct-ligated mouse.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(4):G709-16.
2006: Bambha Kiran; Nagorney David; Sanderson Schuyler; Gores Gregory J
Hepatic adenomatosis in a young woman with glucose intolerance.
Nature clinical practice. Gastroenterology & hepatology 2006;3(9):526-31; quiz (following 531).
2006: LaRusso Nicholas F; Shneider Benjamin L; Black Dennis; Gores Gregory J; James Stephen P; Doo Edward; Hoofnagle Jay H
Primary sclerosing cholangitis: summary of a workshop.
Hepatology (Baltimore, Md.) 2006;44(3):746-64.
2006: Roberts Lewis R; Gores Gregory J
Emerging drugs for hepatocellular carcinoma.
Expert opinion on emerging drugs 2006;11(3):469-87.
2006: Heimbach Julie K; Gores Gregory J; Nagorney David M; Rosen Charles B
Liver transplantation for perihilar cholangiocarcinoma after aggressive neoadjuvant therapy: a new paradigm for liver and biliary malignancies?
Surgery 2006;140(3):331-4.
2006: Malhi Harmeet; Gores Gregory J
Cancer therapy: back to metabolism.
Cancer biology & therapy 2006;5(8):986-7.
2006: Simmons Dia T; Baron Todd H; Petersen Bret T; Gostout Christopher J; Haddock Michael G; Gores Gregory J; Yeakel Peter D; Topazian Mark D; Levy Michael J
A novel endoscopic approach to brachytherapy in the management of Hilar cholangiocarcinoma.
The American journal of gastroenterology 2006;101(8):1792-6.
2006: Baskin-Bey Edwina S; Huang Wendong; Ishimura Norihisa; Isomoto Hajime; Bronk Steven F; Braley Karen; Craig Ruth W; Moore David D; Gores Gregory J
Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins.
Hepatology (Baltimore, Md.) 2006;44(1):252-62.
2006: Varela Maria; Sanchez William; Bruix Jordi; Gores Gregory J
Hepatocellular carcinoma in the setting of liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006;12(7):1028-36.
2006: Xu Xiaoling; Kobayashi Shogo; Qiao Wenhui; Li Cuiling; Xiao Cuiying; Radaeva Svetlana; Stiles Bangyan; Wang Rui-Hong; Ohara Nobuya; Yoshino Tadashi; LeRoith Derek; Torbenson Michael S; Gores Gregory J; Wu Hong; Gao Bin; Deng Chu-Xia
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.
The Journal of clinical investigation 2006;116(7):1843-52.
2006: Feldstein Ariel E; Werneburg Nathan W; Li Zhengzheng; Bronk Steven F; Gores Gregory J
Bax inhibition protects against free fatty acid-induced lysosomal permeabilization.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(6):G1339-46.
2006: Malhi H; Gores G J
Review article: the modern diagnosis and therapy of cholangiocarcinoma.
Alimentary pharmacology & therapeutics 2006;23(9):1287-96.
2006: Malhi Harmeet; Bronk Steven F; Werneburg Nathan W; Gores Gregory J
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis.
The Journal of biological chemistry 2006;281(17):12093-101.
2006: van Vilsteren Frederike G I; Baskin-Bey Edwina S; Nagorney David M; Sanderson Schuyler O; Kremers Walter K; Rosen Charles B; Gores Gregory J; Hobday Timothy J
Liver transplantation for gastroenteropancreatic neuroendocrine cancers: Defining selection criteria to improve survival.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006;12(3):448-56.
2006: Lazaridis Konstantinos N; Gores Gregory J
Primary sclerosing cholangitis and cholangiocarcinoma.
Seminars in liver disease 2006;26(1):42-51.
2006: Malhi Harmeet; Gores Gregory J; Lemasters John J
Apoptosis and necrosis in the liver: a tale of two deaths?
Hepatology (Baltimore, Md.) 2006;43(2 Suppl 1):S31-44.
2006: Kim W Ray; Therneau Terry M; Benson Joanne T; Kremers Walter K; Rosen Charles B; Gores Gregory J; Dickson E Rolland
Deaths on the liver transplant waiting list: an analysis of competing risks.
Hepatology (Baltimore, Md.) 2006;43(2):345-51.
2006: Anan Akira; Baskin-Bey Edwina S; Bronk Steven F; Werneburg Nathan W; Shah Vijay H; Gores Gregory J
Proteasome inhibition induces hepatic stellate cell apoptosis.
Hepatology (Baltimore, Md.) 2006;43(2):335-44.
2006: Sanchez William; Talwalkar Jayant A; Gores Gregory J
"Will all liver transplantation patients eventually die from cancer?".
Journal of hepatology 2006;44(1):13-8.
2006: Ishimura Norihisa; Isomoto Hajime; Bronk Steven F; Gores Gregory J
Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(1):G129-36.
2005: Isomoto Hajime; Kobayashi Shogo; Werneburg Nathan W; Bronk Steve F; Guicciardi Maria Eugenia; Frank David A; Gores Gregory J
Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells.
Hepatology (Baltimore, Md.) 2005;42(6):1329-38.
2005: Baskin-Bey E S; Gores G J
Death by association: BH3 domain-only proteins and liver injury.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(6):G987-90.
2005: Baskin-Bey Edwina S; Gores Gregory J
Caspase-8, death-receptor signaling, and hepatocarcinogenesis: the Fas and the furious.
Gastroenterology 2005;129(5):1790-2.
2005: Wuestefeld Torsten; Klein Christian; Streetz Konrad L; Beraza Naiara; Schölmerich Jürgen; Burgart Lawrence J; Zender Lars; Kubicka Stefan; Baskin-Bey Edwina; Gores Gregory J; Manns Michael P; Trautwein Christian
Lack of gp130 expression results in more bacterial infection and higher mortality during chronic cholestasis in mice.
Hepatology (Baltimore, Md.) 2005;42(5):1082-90.
2005: Gawrieh Samer; Papouchado Bettina G; Burgart Lawrence J; Kobayashi Shogo; Charlton Michael R; Gores Gregory J
Early hepatic stellate cell activation predicts severe hepatitis C recurrence after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(10):1207-13.
2005: Yu Chunrong; Bruzek Laura M; Meng Xue Wei; Gores Gregory J; Carter Christopher A; Kaufmann Scott H; Adjei Alex A
The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.
Oncogene 2005;24(46):6861-9.
2005: Rea David J; Heimbach Julie K; Rosen Charles B; Haddock Michael G; Alberts Steven R; Kremers Walter K; Gores Gregory J; Nagorney David M
Liver transplantation with neoadjuvant chemoradiation is more effective than resection for hilar cholangiocarcinoma.
Annals of surgery 2005;242(3):451-8; discussion 458-61.
2005: Levy Cynthia; Lymp James; Angulo Paul; Gores Gregory J; Larusso Nicholas; Lindor Keith D
The value of serum CA 19-9 in predicting cholangiocarcinomas in patients with primary sclerosing cholangitis.
Digestive diseases and sciences 2005;50(9):1734-40.
2005: Anan Akira; Gores Gregory J
A new TRAIL to therapy of hepatocellular carcinoma: blocking the proteasome.
Hepatology (Baltimore, Md.) 2005;42(3):527-9.
2005: Minagawa Noritaka; Kruglov Emma A; Dranoff Jonathan A; Robert Marie E; Gores Gregory J; Nathanson Michael H
The anti-apoptotic protein Mcl-1 inhibits mitochondrial Ca2+ signals.
The Journal of biological chemistry 2005;280(39):33637-44.
2005: Kim W Ray; Gores Gregory J; Benson Joanne T; Therneau Terry M; Melton L Joseph
Mortality and hospital utilization for hepatocellular carcinoma in the United States.
Gastroenterology 2005;129(2):486-93.
2005: Guicciardi M Eugenia; Bronk Steven F; Werneburg Nathan W; Yin Xiao-Ming; Gores Gregory J
Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis.
Gastroenterology 2005;129(1):269-84.
2005: Guicciardi M E; Gores G J
Apoptosis: a mechanism of acute and chronic liver injury.
Gut 2005;54(7):1024-33.
2005: Kobayashi Shogo; Werneburg Nathan W; Bronk Steven F; Kaufmann Scott H; Gores Gregory J
Interleukin-6 contributes to Mcl-1 up-regulation and TRAIL resistance via an Akt-signaling pathway in cholangiocarcinoma cells.
Gastroenterology 2005;128(7):2054-65.
2005: Lazaridis Konstantinos N; Gores Gregory J
Cholangiocarcinoma.
Gastroenterology 2005;128(6):1655-67.
2005: Ishimura Norihisa; Bronk Steven F; Gores Gregory J
Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis.
Gastroenterology 2005;128(5):1354-68.
2005: Feldstein Ariel E; Papouchado Bettina G; Angulo Paul; Sanderson Schyler; Adams Leon; Gores Gregory J
Hepatic stellate cells and fibrosis progression in patients with nonalcoholic fatty liver disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(4):384-9.
2005: Slijkhuis Wilco A; Stadheim Linda; Hassoun Ziad M; Nzeako Ugochukwu C; Kremers Walter K; Talwalkar Jayant A; Gores Gregory J
Octreotide therapy for advanced hepatocellular carcinoma.
Journal of clinical gastroenterology 2005;39(4):333-8.
2005: Stewart Charmaine A; Reivich Martin; Lucey Michael R; Gores Gregory J
Neuroimaging in hepatic encephalopathy.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(3):197-207.
2005: Harewood Gavin C; Baron Todd H; Rumalla Ashwin; Wang Kenneth K; Gores Gregory J; Stadheim Linda M; de Groen Piet C
Pilot study to assess patient outcomes following endoscopic application of photodynamic therapy for advanced cholangiocarcinoma.
Journal of gastroenterology and hepatology 2005;20(3):415-20.
2005: Gwak Geum-Youn; Yoon Jung-Hwan; Kim Kang Mo; Lee Hyo-Suk; Chung Jin Wook; Gores Gregory J
Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression.
Journal of hepatology 2005;42(3):358-64.
2005: Guicciardi Maria Eugenia; Gores Gregory J
Cholestatic hepatocellular injury: what do we know and how should we proceed.
Journal of hepatology 2005;42(3):297-300.
2005: Canbay A; Gieseler R K; Gores G J; Gerken G
The relationship between apoptosis and non-alcoholic fatty liver disease: an evolutionary cornerstone turned pathogenic.
Zeitschrift für Gastroenterologie 2005;43(2):211-7.
2005: Baskin-Bey E S; Canbay A; Bronk S F; Werneburg N; Guicciardi M E; Nyberg S L; Gores G J
Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia-warm reperfusion injury.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(2):G396-402.
2005: Ghobrial Irene M; Habermann Thomas M; Macon William R; Ristow Kay M; Larson Timothy S; Walker Randall C; Ansell Stephen M; Gores Gregory J; Stegall Mark D; McGregor Christopher G
Differences between early and late posttransplant lymphoproliferative disorders in solid organ transplant patients: are they two different diseases?
Transplantation 2005;79(2):244-7.
2005: Feldstein Ariel E; Gores Gregory J
Apoptosis in alcoholic and nonalcoholic steatohepatitis.
Frontiers in bioscience : a journal and virtual library 2005;10():3093-9.
2005: Roberts Lewis R; Gores Gregory J
Hepatocellular carcinoma: molecular pathways and new therapeutic targets.
Seminars in liver disease 2005;25(2):212-25.
2004: Chiorean Mihnea V; Guicciardi Maria Eugenia; Yoon Jung-Hwan; Bronk Steven F; Kaufmanns Scott H; Gores Gregory J
Imatinib mesylate induces apoptosis in human cholangiocarcinoma cells.
Liver international : official journal of the International Association for the Study of the Liver 2004;24(6):687-95.
2004: Gores Gregory J; Baskin-Bey Edwina S; Baron Todd H; Alberts Steven R
Treatment endpoints for advanced cholangiocarcinoma.
Nature clinical practice. Gastroenterology & hepatology 2004;1(1):4-5.
2004: Yoon Jung-Hwan; Gwak Geum-Youn; Lee Hyo-Suk; Bronk Steven F; Werneburg Nathan W; Gores Gregory J
Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells.
Journal of hepatology 2004;41(5):808-14.
2004: Talwalkar Jayant A; Gores Gregory J
Diagnosis and staging of hepatocellular carcinoma.
Gastroenterology 2004;127(5 Suppl 1):S126-32.
2004: Johnson Michael E; Uhl Cindy B; Spittler Karl-Heinz; Wang Hongxun; Gores Gregory J
Mitochondrial injury and caspase activation by the local anesthetic lidocaine.
Anesthesiology 2004;101(5):1184-94.
2004: Feldstein Ariel E; Gores Gregory J
An apoptosis biomarker goes to the HCV clinic.
Hepatology (Baltimore, Md.) 2004;40(5):1044-6.
2004: Heimbach Julie K; Haddock Michael G; Alberts Steven R; Nyberg Scott L; Ishitani Michael B; Rosen Charles B; Gores Gregory J
Transplantation for hilar cholangiocarcinoma.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004;10(10 Suppl 2):S65-8.
2004: Feldstein Ariel; Gores Gregory J
Steatohepatitis and apoptosis: therapeutic implications.
The American journal of gastroenterology 2004;99(9):1718-9.
2004: Kipp Benjamin R; Stadheim Linda M; Halling Shari A; Pochron Nicole L; Harmsen Scott; Nagorney David M; Sebo Thomas J; Therneau Terry M; Gores Gregory J; de Groen Piet C; Baron Todd H; Levy Michael J; Halling Kevin C; Roberts Lewis R
A comparison of routine cytology and fluorescence in situ hybridization for the detection of malignant bile duct strictures.
The American journal of gastroenterology 2004;99(9):1675-81.
2004: Werneburg Nate; Guicciardi M Eugenia; Yin Xiao-Ming; Gores Gregory J
TNF-alpha-mediated lysosomal permeabilization is FAN and caspase 8/Bid dependent.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(2):G436-43.
2004: Feldstein Ariel E; Werneburg Nathan W; Canbay Ali; Guicciardi Maria Eugenia; Bronk Steven F; Rydzewski Robert; Burgart Laurence J; Gores Gregory J
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway.
Hepatology (Baltimore, Md.) 2004;40(1):185-94.
2004: Ishimura Norihisa; Bronk Steven F; Gores Gregory J
Inducible nitric oxide synthase upregulates cyclooxygenase-2 in mouse cholangiocytes promoting cell growth.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G88-95.
2004: Guicciardi M Eugenia; Gores Gregory J
Cheating death in the liver.
Nature medicine 2004;10(6):587-8.
2004: Heimbach Julie K; Gores Gregory J; Haddock Michael G; Alberts Steven R; Nyberg Scott L; Ishitani Michael B; Rosen Charles B
Liver transplantation for unresectable perihilar cholangiocarcinoma.
Seminars in liver disease 2004;24(2):201-7.
2004: Taniai Makiko; Grambihler Annette; Higuchi Hajime; Werneburg Nate; Bronk Steve F; Farrugia Daniel J; Kaufmann Scott H; Gores Gregory J
Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.
Cancer research 2004;64(10):3517-24.
2004: Matsumura Shuji; Van De Water Judy; Leung Patrick; Odin Joseph A; Yamamoto Kazuhide; Gores Gregory J; Mostov Keith; Ansari Aftab A; Coppel Ross L; Shiratori Yasushi; Gershwin M Eric
Caspase induction by IgA antimitochondrial antibody: IgA-mediated biliary injury in primary biliary cirrhosis.
Hepatology (Baltimore, Md.) 2004;39(5):1415-22.
2004: Rosado Barbara; Gores Gregory J
Liver transplantation for neuroendocrine tumors: progress and uncertainty.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004;10(5):712-3.
2004: Guicciardi Maria Eugenia; Leist Marcel; Gores Gregory J
Lysosomes in cell death.
Oncogene 2004;23(16):2881-90.
2004: Clary Bryan; Jarnigan William; Pitt Henry; Gores Gregory; Busuttil Ronald; Pappas Theodore
Hilar cholangiocarcinoma.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2004;8(3):298-302.
2004: Baron Todd H; Harewood Gavin C; Rumalla Ashwin; Pochron Nicole L; Stadheim Linda M; Gores Gregory J; Therneau Terry M; De Groen Piet C; Sebo Thomas J; Salomao Diva R; Kipp Benjamin R
A prospective comparison of digital image analysis and routine cytology for the identification of malignancy in biliary tract strictures.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004;2(3):214-9.
2004: Maddala Yamini K; Stadheim Linda; Andrews James C; Burgart Lawrence J; Rosen Charles B; Kremers Walter K; Gores Gregory
Drop-out rates of patients with hepatocellular cancer listed for liver transplantation: outcome with chemoembolization.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004;10(3):449-55.
2004: Yoon Jung-Hwan; Canbay Ali E; Werneburg Nathan W; Lee Sum P; Gores Gregory J
Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis.
Hepatology (Baltimore, Md.) 2004;39(3):732-8.
2004: Strand Susanne; Strand Dennis; Seufert Rudolf; Mann Amrit; Lotz Johannes; Blessing Manfred; Lahn Michael; Wunsch Andreas; Broering Dieter C; Hahn Uwe; Grischke Eva-Maria; Rogiers Xavier; Otto Gerd; Gores Gregory J; Galle Peter R
Placenta-derived CD95 ligand causes liver damage in hemolysis, elevated liver enzymes, and low platelet count syndrome.
Gastroenterology 2004;126(3):849-58.
2004: Canbay Ali; Feldstein Ariel; Baskin-Bey Edwina; Bronk Steven F; Gores Gregory J
The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse.
The Journal of pharmacology and experimental therapeutics 2004;308(3):1191-6.
2004: Menon K V Narayanan; Stadheim Linda; Kamath Patrick S; Wiesner Russell H; Gores Gregory J; Peine Craig J; Shah Vijay
A pilot study of the safety and tolerability of etanercept in patients with alcoholic hepatitis.
The American journal of gastroenterology 2004;99(2):255-60.
2004: Canbay Ali; Friedman Scott; Gores Gregory J
Apoptosis: the nexus of liver injury and fibrosis.
Hepatology (Baltimore, Md.) 2004;39(2):273-8.
2004: Higuchi Hajime; Grambihler Annette; Canbay Ali; Bronk Steven F; Gores Gregory J
Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1.
The Journal of biological chemistry 2004;279(1):51-60.
2004: Maeda Takashi; Taguchi Ken-ichi; Aishima Shin-ichi; Shimada Mitsuo; Hintz Deborah; Larusso Nicholas; Gores Gregory; Tsuneyoshi Masazumi; Sugimachi Keizo; Wands Jack R; de la Monte Suzanne M
Clinicopathological correlates of aspartyl (asparaginyl) beta-hydroxylase over-expression in cholangiocarcinoma.
Cancer detection and prevention 2004;28(5):313-8.
2003: Feldstein Ariel E; Canbay Ali; Guicciardi Maria E; Higuchi Hajime; Bronk Steven F; Gores Gregory J
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice.
Journal of hepatology 2003;39(6):978-83.
2003: Gores Gregory J
A spotlight on cholangiocarcinoma.
Gastroenterology 2003;125(5):1536-8.
2003: Canbay Ali; Feldstein Ariel E; Higuchi Hajime; Werneburg Nate; Grambihler Annette; Bronk Steve F; Gores Gregory J
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression.
Hepatology (Baltimore, Md.) 2003;38(5):1188-98.
2003: Guicciardi M Eugenia; Gores Gregory J
Targeted use of siRNA in animal models of hepatic damage: an innovative therapy for acute liver failure.
Journal of hepatology 2003;39(5):883-5.
2003: Higuchi Hajime; Gores Gregory J
Mechanisms of liver injury: an overview.
Current molecular medicine 2003;3(6):483-90.
2003: Di Bisceglie Adrian M; Lyra Andre C; Schwartz Myron; Reddy Rajender K; Martin Paul; Gores Gregory; Lok Anna S F; Hussain Khozema B; Gish Robert; Van Thiel David H; Younossi Zobair; Tong Myron; Hassanein Tarek; Balart Luis; Fleckenstein Jacquelyn; Flamm Stephen; Blei Andres; Befeler Alex S;
Hepatitis C-related hepatocellular carcinoma in the United States: influence of ethnic status.
The American journal of gastroenterology 2003;98(9):2060-3.
2003: Janssen Harry L A; Higuchi Hajime; Abdulkarim Ahmad; Gores Gregory J
Hepatitis B virus enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity by increasing TRAIL-R1/death receptor 4 expression.
Journal of hepatology 2003;39(3):414-20.
2003: Peterson Timothy E; Guicciardi Maria E; Gulati Rajiv; Kleppe Laurel S; Mueske Cheryl S; Mookadam Martina; Sowa Grzegorz; Gores Gregory J; Sessa William C; Simari Robert D
Caveolin-1 can regulate vascular smooth muscle cell fate by switching platelet-derived growth factor signaling from a proliferative to an apoptotic pathway.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(9):1521-7.
2003: Feldstein Ariel E; Canbay Ali; Angulo Paul; Taniai Makiko; Burgart Lawrence J; Lindor Keith D; Gores Gregory J
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis.
Gastroenterology 2003;125(2):437-43.
2003: Canbay Ali; Guicciardi Maria Eugenia; Higuchi Hajime; Feldstein Ariel; Bronk Steven F; Rydzewski Robert; Taniai Makiko; Gores Gregory J
Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis.
The Journal of clinical investigation 2003;112(2):152-9.
2003: Grambihler Annette; Higuchi Hajime; Bronk Steven F; Gores Gregory J
cFLIP-L inhibits p38 MAPK activation: an additional anti-apoptotic mechanism in bile acid-mediated apoptosis.
The Journal of biological chemistry 2003;278(29):26831-7.
2003: Werneburg Nathan W; Yoon Jung-Hwan; Higuchi Hajime; Gores Gregory J
Bile acids activate EGF receptor via a TGF-alpha-dependent mechanism in human cholangiocyte cell lines.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(1):G31-6.
2003: Stadheim Linda M; O'Brien John F; Lindor Keith D; Gores Gregory J; McGill Douglas B
Value of determining carbohydrate-deficient transferrin isoforms in the diagnosis of alcoholic liver disease.
Mayo Clinic proceedings. Mayo Clinic 2003;78(6):703-7.
2003: Guicciardi M Eugenia; Gores Gregory J
AIP1: a new player in TNF signaling.
The Journal of clinical investigation 2003;111(12):1813-5.
2003: Canbay Ali; Taimr Pavel; Torok Natalie; Higuchi Hajime; Friedman Scott; Gores Gregory J
Apoptotic body engulfment by a human stellate cell line is profibrogenic.
Laboratory investigation; a journal of technical methods and pathology 2003;83(5):655-63.
2003: Gores Gregory J
Cholangiocarcinoma: current concepts and insights.
Hepatology (Baltimore, Md.) 2003;37(5):961-9.
2003: Decker G Anton; Gores Gregory J; Roberts Lewis R
Tumor seeding complicating radiofrequency ablation of hepatocellular carcinoma.
Journal of hepatology 2003;38(5):692.
2003: Gores Gregory J
Cholangiocarcinoma: preventing invasion as anti-cancer strategy.
Journal of hepatology 2003;38(5):671-3.
2003: Higuchi Hajime; Gores Gregory J
Bile acid regulation of hepatic physiology: IV. Bile acids and death receptors.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(5):G734-8.
2003: Guicciardi Maria Eugenia; Gores Gregory J
Calpains can do it alone: implications for cancer therapy.
Cancer biology & therapy 2003;2(2):153-4.
2003: Natori Shiho; Higuchi Hajime; Contreras Patricia; Gores Gregory J
The caspase inhibitor IDN-6556 prevents caspase activation and apoptosis in sinusoidal endothelial cells during liver preservation injury.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2003;9(3):278-84.
2003: Gores Gregory J
Hepatocellular carcinoma: gardening strategies and bridges to transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2003;9(2):199-200.
2003: Hassoun Ziad; Gores Gregory J
Treatment of hepatocellular carcinoma.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2003;1(1):10-8.
2003: Hassoun Ziad; Gores Gregory J
What surgeons should know about viral hepatitis and hepatocellular carcinoma.
Surgical oncology clinics of North America 2003;12(1):1-11, vii.
2003: Taimr Pavel; Higuchi Hajime; Kocova Eva; Rippe Richard A; Friedman Scott; Gores Gregory J
Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis.
Hepatology (Baltimore, Md.) 2003;37(1):87-95.
2003: Higuchi Hajime; Yoon Jung-Hwan; Grambihler Annette; Werneburg Nathan; Bronk Steven F; Gores Gregory J
Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosis.
The Journal of biological chemistry 2003;278(1):454-61.
2003: Matsushita Takakazu; Yagi Toshikazu; Hardin Joseph A; Cragun Jennifer D; Crow Frank W; Bergen H Robert; Gores Gregory J; Nyberg Scott L
Apoptotic cell death and function of cryopreserved porcine hepatocytes in a bioartificial liver.
Cell transplantation 2003;12(2):109-21.
2002: Holzknecht Zoie E; Kuypers Karisha L; Plummer Timothy B; Williams Josie; Bustos Matilda; Gores Gregory J; Brunn Gregory J; Platt Jeffrey L
Apoptosis and cellular activation in the pathogenesis of acute vascular rejection.
Circulation research 2002;91(12):1135-41.
2002: Sorom Abraham J; Nyberg Scott L; Gores Gregory J
Keratin, fas, and cryptogenic liver failure.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2002;8(12):1195-7.
2002: Johnson Michael E; Saenz J Armando; DaSilva Assir Daniel; Uhl Cindy B; Gores Gregory J
Effect of local anesthetic on neuronal cytoplasmic calcium and plasma membrane lysis (necrosis) in a cell culture model.
Anesthesiology 2002;97(6):1466-76.
2002: Yoon Jung-Hwan; Werneburg Nathan W; Higuchi Hajime; Canbay Ali E; Kaufmann Scott H; Akgul Cahit; Edwards Steven W; Gores Gregory J
Bile acids inhibit Mcl-1 protein turnover via an epidermal growth factor receptor/Raf-1-dependent mechanism.
Cancer research 2002;62(22):6500-5.
2002: Higuchi Hajime; Bronk Steven F; Taniai Makiko; Canbay Ali; Gores Gregory J
Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity.
The Journal of pharmacology and experimental therapeutics 2002;303(2):461-7.
2002: Arnt Christina R; Chiorean Mihnea V; Heldebrant Michael P; Gores Gregory J; Kaufmann Scott H
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ.
The Journal of biological chemistry 2002;277(46):44236-43.
2002: Hassoun Ziad; Gores Gregory J; Rosen Charles B
Preliminary experience with liver transplantation in selected patients with unresectable hilar cholangiocarcinoma.
Surgical oncology clinics of North America 2002;11(4):909-21.
2002: Canbay Ali; Higuchi Hajime; Bronk Steven F; Taniai Makiko; Sebo Tom J; Gores Gregory J
Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.
Gastroenterology 2002;123(4):1323-30.
2002: Taniai Makiko; Higuchi Hajime; Burgart Lawrence J; Gores Gregory J
p16INK4a promoter mutations are frequent in primary sclerosing cholangitis (PSC) and PSC-associated cholangiocarcinoma.
Gastroenterology 2002;123(4):1090-8.
2002: Werneburg Nathan W; Guicciardi M Eugenia; Bronk Steven F; Gores Gregory J
Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(4):G947-56.
2002: Yoon Jung-Hwan; Gores Gregory J
Death receptor-mediated apoptosis and the liver.
Journal of hepatology 2002;37(3):400-10.
2002: Gores Gregory J
Yes, hepatocellular cancer does occur in primary biliary cirrhosis.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2002;8(6):570-1.
2002: Buckles Daniel C; Lindor Keith D; Larusso Nicholas F; Petrovic Lydia M; Gores Gregory J
In primary sclerosing cholangitis, gallbladder polyps are frequently malignant.
The American journal of gastroenterology 2002;97(5):1138-42.
2002: Guicciardi M Eugenia; Gores Gregory J
Ursodeoxycholic acid cytoprotection: dancing with death receptors and survival pathways.
Hepatology (Baltimore, Md.) 2002;35(4):971-3.
2002: Yoon Jung-Hwan; Higuchi Hajime; Werneburg Nathan W; Kaufmann Scott H; Gores Gregory J
Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line.
Gastroenterology 2002;122(4):985-93.
2002: Nzeako Ugochukwu C; Gores Gregory J
Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by cyclooxygenase inhibitors.
Cancer 2002;94(6):1903-4.
2002: Török Natalie J; Higuchi Hajime; Bronk Steven; Gores Gregory J
Nitric oxide inhibits apoptosis downstream of cytochrome C release by nitrosylating caspase 9.
Cancer research 2002;62(6):1648-53.
2002: Nzeako Ugochukwu C; Guicciardi Maria Eugenia; Yoon Jung-Hwan; Bronk Steven F; Gores Gregory J
COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells.
Hepatology (Baltimore, Md.) 2002;35(3):552-9.
2002: Jaeschke Hartmut; Gores Gregory J; Cederbaum Arthur I; Hinson Jack A; Pessayre Dominique; Lemasters John J
Mechanisms of hepatotoxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2002;65(2):166-76.
2001: Guicciardi M E; Miyoshi H; Bronk S F; Gores G J
Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications.
The American journal of pathology 2001;159(6):2045-54.
2001: Higuchi H; Miyoshi H; Bronk S F; Zhang H; Dean N; Gores G J
Bid antisense attenuates bile acid-induced apoptosis and cholestatic liver injury.
The Journal of pharmacology and experimental therapeutics 2001;299(3):866-73.
2001: Menon K V; Gores G J; Shah V H
Pathogenesis, diagnosis, and treatment of alcoholic liver disease.
Mayo Clinic proceedings. Mayo Clinic 2001;76(10):1021-9.
2001: Higuchi H; Bronk S F; Takikawa Y; Werneburg N; Takimoto R; El-Deiry W; Gores G J
The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis.
The Journal of biological chemistry 2001;276(42):38610-8.
2001: Jaiswal M; LaRusso N F; Gores G J
Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(3):G626-34.
2001: Lazaridis K N; Gores G J; Lindor K D
Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'.
Journal of hepatology 2001;35(1):134-46.
2001: Gores G J; Kaufmann S H
Is TRAIL hepatotoxic?
Hepatology (Baltimore, Md.) 2001;34(1):3-6.
2001: Yagi T; Hardin J A; Valenzuela Y M; Miyoshi H; Gores G J; Nyberg S L
Caspase inhibition reduces apoptotic death of cryopreserved porcine hepatocytes.
Hepatology (Baltimore, Md.) 2001;33(6):1432-40.
2001: Takikawa Y; Miyoshi H; Rust C; Roberts P; Siegel R; Mandal P K; Millikan R E; Gores G J
The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes.
Gastroenterology 2001;120(7):1810-7.
2001: Chen X M; Levine S A; Splinter P L; Tietz P S; Ganong A L; Jobin C; Gores G J; Paya C V; LaRusso N F
Cryptosporidium parvum activates nuclear factor kappaB in biliary epithelia preventing epithelial cell apoptosis.
Gastroenterology 2001;120(7):1774-83.
2001: Souto E O; Miyoshi H; Dubois R N; Gores G J
Kupffer cell-derived cyclooxygenase-2 regulates hepatocyte Bcl-2 expression in choledocho-venous fistula rats.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(5):G805-11.
2001: Kaya M; de Groen P C; Angulo P; Nagorney D M; Gunderson L L; Gores G J; Haddock M G; Lindor K D
Treatment of cholangiocarcinoma complicating primary sclerosing cholangitis: the Mayo Clinic experience.
The American journal of gastroenterology 2001;96(4):1164-9.
2001: Rumalla A; Baron T H; Wang K K; Gores G J; Stadheim L M; de Groen P C
Endoscopic application of photodynamic therapy for cholangiocarcinoma.
Gastrointestinal endoscopy 2001;53(4):500-4.
2001: Miyoshi H; Rust C; Guicciardi M E; Gores G J
NF-kappaB is activated in cholestasis and functions to reduce liver injury.
The American journal of pathology 2001;158(3):967-75.
2001: Natori S; Rust C; Stadheim L M; Srinivasan A; Burgart L J; Gores G J
Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis.
Journal of hepatology 2001;34(2):248-53.
2001: Rust C; Gores G J
Locoregional management of hepatocellular carcinoma. Surgical and ablation therapies.
Clinics in liver disease 2001;5(1):161-73.
2001: Jaiswal M; LaRusso N F; Shapiro R A; Billiar T R; Gores G J
Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes.
Gastroenterology 2001;120(1):190-9.
2000: Higuchi H; Bronk S F; Bateman A; Harrington K; Vile R G; Gores G J
Viral fusogenic membrane glycoprotein expression causes syncytia formation with bioenergetic cell death: implications for gene therapy.
Cancer research 2000;60(22):6396-402.
2000: Guicciardi M E; Deussing J; Miyoshi H; Bronk S F; Svingen P A; Peters C; Kaufmann S H; Gores G J
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c.
The Journal of clinical investigation 2000;106(9):1127-37.
2000: Kaufmann S H; Gores G J
Apoptosis in cancer: cause and cure.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(11):1007-17.
2000: Guicciardi M E; Gores G J
Dying in Fas traffic.
Hepatology (Baltimore, Md.) 2000;32(2):439-40.
2000: Sodeman T; Bronk S F; Roberts P J; Miyoshi H; Gores G J
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(6):G992-9.
2000: Rust C; Karnitz L M; Paya C V; Moscat J; Simari R D; Gores G J
The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.
The Journal of biological chemistry 2000;275(26):20210-6.
2000: De Vreede I; Steers J L; Burch P A; Rosen C B; Gunderson L L; Haddock M G; Burgart L; Gores G J
Prolonged disease-free survival after orthotopic liver transplantation plus adjuvant chemoirradiation for cholangiocarcinoma.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2000;6(3):309-16.
2000: Rust C; Gores G J
Apoptosis and liver disease.
The American journal of medicine 2000;108(7):567-74.
2000: Nyberg S L; Hardin J A; Matos L E; Rivera D J; Misra S P; Gores G J
Cytoprotective influence of ZVAD-fmk and glycine on gel-entrapped rat hepatocytes in a bioartificial liver.
Surgery 2000;127(4):447-55.
2000: Poggio J L; Rowland C M; Gores G J; Nagorney D M; Donohue J H
A comparison of laparoscopic and open cholecystectomy in patients with compensated cirrhosis and symptomatic gallstone disease.
Surgery 2000;127(4):405-11.
2000: Ribeiro A; Nagorney D M; Gores G J
Localized hepatocellular carcinoma: therapeutic options.
Current gastroenterology reports 2000;2(1):72-81.
2000: Jaiswal M; LaRusso N F; Burgart L J; Gores G J
Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism.
Cancer research 2000;60(1):184-90.
2000: Patel A H; Harnois D M; Klee G G; LaRusso N F; Gores G J
The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis.
The American journal of gastroenterology 2000;95(1):204-7.
1999: Lazaridis K N; Gores G J
Liver mass in a patient with primary sclerosing cholangitis.
Journal of hepatology 1999;31(6):1086.
1999: Ribeiro A; Bronk S F; Roberts P J; Urrutia R; Gores G J
The transforming growth factor beta(1)-inducible transcription factor TIEG1, mediates apoptosis through oxidative stress.
Hepatology (Baltimore, Md.) 1999;30(6):1490-7.
1999: Que F G; Phan V A; Phan V H; Celli A; Batts K; LaRusso N F; Gores G J
Cholangiocarcinomas express Fas ligand and disable the Fas receptor.
Hepatology (Baltimore, Md.) 1999;30(6):1398-404.
1999: Park J; Tadlock L; Gores G J; Patel T
Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line.
Hepatology (Baltimore, Md.) 1999;30(5):1128-33.
1999: Chen X M; Gores G J; Paya C V; LaRusso N F
Cryptosporidium parvum induces apoptosis in biliary epithelia by a Fas/Fas ligand-dependent mechanism.
The American journal of physiology 1999;277(3 Pt 1):G599-608.
1999: Miyoshi H; Rust C; Roberts P J; Burgart L J; Gores G J
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.
Gastroenterology 1999;117(3):669-77.
1999: Natori S; Selzner M; Valentino K L; Fritz L C; Srinivasan A; Clavien P A; Gores G J
Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism.
Transplantation 1999;68(1):89-96.
1999: Que F G; Phan V A; Phan V H; LaRusso N F; Gores G J
GUDC inhibits cytochrome c release from human cholangiocyte mitochondria.
The Journal of surgical research 1999;83(2):100-5.
1999: Harnois D M; Steers J; Andrews J C; Rubin J C; Pitot H C; Burgart L; Wiesner R H; Gores G J
Preoperative hepatic artery chemoembolization followed by orthotopic liver transplantation for hepatocellular carcinoma.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1999;5(3):192-9.
1999: Park J; Gores G J; Patel T
Lipopolysaccharide induces cholangiocyte proliferation via an interleukin-6-mediated activation of p44/p42 mitogen-activated protein kinase.
Hepatology (Baltimore, Md.) 1999;29(4):1037-43.
1999: Rivera D J; Gores G J; Misra S P; Hardin J A; Nyberg S L
Apoptosis by gel-entrapped hepatocytes in a bioartificial liver.
Transplantation proceedings 1999;31(1-2):671-3.
1999: Faubion W A; Guicciardi M E; Miyoshi H; Bronk S F; Roberts P J; Svingen P A; Kaufmann S H; Gores G J
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.
The Journal of clinical investigation 1999;103(1):137-45.
1999: Faubion W A; Gores G J
Death receptors in liver biology and pathobiology.
Hepatology (Baltimore, Md.) 1999;29(1):1-4.
1999: Roberts L R; Adjei P N; Gores G J
Cathepsins as effector proteases in hepatocyte apoptosis.
Cell biochemistry and biophysics 1999;30(1):71-88.
1998: Kitabayashi K; Gores G J; Krom R A
Arterial ketone body ratio in clinical liver transplantation.
Transplantation proceedings 1998;30(8):4356-9.
1998: Guicciardi M E; Gores G J
Is ursodeoxycholate an antiapoptotic drug?
Hepatology (Baltimore, Md.) 1998;28(6):1721-3.
1998: Celli A; Que F G; Gores G J; LaRusso N F
Glutathione depletion is associated with decreased Bcl-2 expression and increased apoptosis in cholangiocytes.
The American journal of physiology 1998;275(4 Pt 1):G749-57.
1998: Jones B; Roberts P J; Faubion W A; Kominami E; Gores G J
Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line.
The American journal of physiology 1998;275(4 Pt 1):G723-30.
1998: Di Bisceglie A M; Carithers R L; Gores G J
Hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 1998;28(4):1161-5.
1998: Ribeiro A; Burgart L J; Nagorney D M; Gores G J
Management of liver adenomatosis: results with a conservative surgical approach.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1998;4(5):388-98.
1998: Gores G J; Miyoshi H; Botla R; Aguilar H I; Bronk S F
Induction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: a potential role for mitochondrial proteases.
Biochimica et biophysica acta 1998;1366(1-2):167-75.
1998: Jones B A; Gores G J
Hepatobiliary malignancy.
Clinics in liver disease 1998;2(2):437-49, xi-xii.
1998: Karnes W E; Weller S G; Adjei P N; Kottke T J; Glenn K S; Gores G J; Kaufmann S H
Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells.
Gastroenterology 1998;114(5):930-9.
1998: Patel T; Gores G J
Apoptosis in liver transplantation: a mechanism contributing to immune modulation, preservation injury, neoplasia, and viral disease.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1998;4(1):42-50.
1998: Patel T; Roberts L R; Jones B A; Gores G J
Dysregulation of apoptosis as a mechanism of liver disease: an overview.
Seminars in liver disease 1998;18(2):105-14.
1997: Jones B A; Gores G J
Physiology and pathophysiology of apoptosis in epithelial cells of the liver, pancreas, and intestine.
The American journal of physiology 1997;273(6 Pt 1):G1174-88.
1997: Roberts L R; Kurosawa H; Bronk S F; Fesmier P J; Agellon L B; Leung W Y; Mao F; Gores G J
Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes.
Gastroenterology 1997;113(5):1714-26.
1997: Harnois D M; Que F G; Celli A; LaRusso N F; Gores G J
Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line.
Hepatology (Baltimore, Md.) 1997;26(4):884-90.
1997: Harnois D M; Gores G J; Ludwig J; Steers J L; LaRusso N F; Wiesner R H
Are patients with cirrhotic stage primary sclerosing cholangitis at risk for the development of hepatocellular cancer?
Journal of hepatology 1997;27(3):512-6.
1997: Kurosawa H; Que F G; Roberts L R; Fesmier P J; Gores G J
Hepatocytes in the bile duct-ligated rat express Bcl-2.
The American journal of physiology 1997;272(6 Pt 1):G1587-93.
1997: Jones B A; Rao Y P; Stravitz R T; Gores G J
Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C.
The American journal of physiology 1997;272(5 Pt 1):G1109-15.
1997: Arora A S; Jones B J; Patel T C; Bronk S F; Gores G J
Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat.
Hepatology (Baltimore, Md.) 1997;25(4):958-63.
1997: Aguilar H I; Steers J L; Wiesner R H; Krom R A; Gores G J
Enhanced liver calpain protease activity is a risk factor for dysfunction of human liver allografts.
Transplantation 1997;63(4):612-4.
1997: Que F G; Gores G J; LaRusso N F
Development and initial application of an in vitro model of apoptosis in rodent cholangiocytes.
The American journal of physiology 1997;272(1 Pt 1):G106-15.
1997: Patel T; Gores G J
Inhibition of bile-salt-induced hepatocyte apoptosis by the antioxidant lazaroid U83836E.
Toxicology and applied pharmacology 1997;142(1):116-22.
1997: Zeid I M; Bronk S F; Fesmier P J; Gores G J
Cytoprotection by fructose and other ketohexoses during bile salt-induced apoptosis of hepatocytes.
Hepatology (Baltimore, Md.) 1997;25(1):81-6.
1996: Marsman W A; Moore S B; Kondo M; Bundy K L; Gores G J; Wiesner R H; Krom R A
Do cold agglutinins have any impact on the outcome of liver transplantation?
Transplantation 1996;62(11):1673-6.
1996: Adjei P N; Kaufmann S H; Leung W Y; Mao F; Gores G J
Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32.
The Journal of clinical investigation 1996;98(11):2588-96.
1996: Marsman W A; Wiesner R H; Rodriguez L; Batts K P; Porayko M K; Hay J E; Gores G J; Krom R A
Use of fatty donor liver is associated with diminished early patient and graft survival.
Transplantation 1996;62(9):1246-51.
1996: Laurin J; Lindor K D; Crippin J S; Gossard A; Gores G J; Ludwig J; Rakela J; McGill D B
Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study.
Hepatology (Baltimore, Md.) 1996;23(6):1464-7.
1996: Arora A S; de Groen P C; Croall D E; Emori Y; Gores G J
Hepatocellular carcinoma cells resist necrosis during anoxia by preventing phospholipase-mediated calpain activation.
Journal of cellular physiology 1996;167(3):434-42.
1996: Patel T; Gores G J; Kaufmann S H
The role of proteases during apoptosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(5):587-97.
1996: Que F G; Gores G J
Cell death by apoptosis: basic concepts and disease relevance for the gastroenterologist.
Gastroenterology 1996;110(4):1238-43.
1996: Lindor K D; Jorgensen R A; Anderson M L; Gores G J; Hofmann A F; LaRusso N F
Ursodeoxycholic acid and methotrexate for primary sclerosing cholangitis: a pilot study.
The American journal of gastroenterology 1996;91(3):511-5.
1996: Arora A S; de Groen P; Emori Y; Gores G J
A cascade of degradative hydrolase activity contributes to hepatocyte necrosis during anoxia.
The American journal of physiology 1996;270(2 Pt 1):G238-45.
1996: Arora A S; Gores G J
The role of metals in ischemia/reperfusion injury of the liver.
Seminars in liver disease 1996;16(1):31-8.
1996: Aguilar H I; Botla R; Arora A S; Bronk S F; Gores G J
Induction of the mitochondrial permeability transition by protease activity in rats: a mechanism of hepatocyte necrosis.
Gastroenterology 1996;110(2):558-66.
1995: Patel T; Arora A; Gores G J
A fluorometric assay for quantitating DNA strand breaks during apoptosis.
Analytical biochemistry 1995;229(2):229-35.
1995: Patel T; Gores G J
Apoptosis and hepatobiliary disease.
Hepatology (Baltimore, Md.) 1995;21(6):1725-41.
1995: Tan C K; Podila P V; Taylor J E; Nagorney D M; Wiseman G A; Gores G J; LaRusso N F
Human cholangiocarcinomas express somatostatin receptors and respond to somatostatin with growth inhibition.
Gastroenterology 1995;108(6):1908-16.
1995: Kwo P; Patel T; Bronk S F; Gores G J
Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes.
The American journal of physiology 1995;268(4 Pt 1):G613-21.
1995: Botla R; Spivey J R; Aguilar H; Bronk S F; Gores G J
Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA cytoprotection.
The Journal of pharmacology and experimental therapeutics 1995;272(2):930-8.
1995: Rosser B G; Gores G J
Liver cell necrosis: cellular mechanisms and clinical implications.
Gastroenterology 1995;108(1):252-75.
1995: Sandborn W J; Lawson G M; Cody T J; Porayko M K; Hay J E; Gores G J; Steers J L; Krom R A; Wiesner R H
Early cellular rejection after orthotopic liver transplantation correlates with low concentrations of FK506 in hepatic tissue.
Hepatology (Baltimore, Md.) 1995;21(1):70-6.
1994: Patel T; Bronk S F; Gores G J
Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes.
The Journal of clinical investigation 1994;94(6):2183-92.
1994: Wiesner R H; Ludwig J; Krom R A; Steers J L; Porayko M K; Gores G J; Hay J E
Treatment of early cellular rejection following liver transplantation with intravenous methylprednisolone. The effect of dose on response.
Transplantation 1994;58(9):1053-6.
1994: Spivey J R; Jorgensen R A; Gores G J; Lindor K D
Methionine-enkephalin concentrations correlate with stage of disease but not pruritus in patients with primary biliary cirrhosis.
The American journal of gastroenterology 1994;89(11):2028-32.
1994: Gates L K; Wiesner R H; Krom R A; Steers J; Gores G J; Hay J E; Porayko M K
Etiology and incidence of unconjugated hyperbilirubinemia after orthotopic liver transplantation.
The American journal of gastroenterology 1994;89(9):1541-3.
1994: Fujii Y; Johnson M E; Gores G J
Mitochondrial dysfunction during anoxia/reoxygenation injury of liver sinusoidal endothelial cells.
Hepatology (Baltimore, Md.) 1994;20(1 Pt 1):177-85.
1994: Tan C K; Gores G J; Steers J L; Porayko M K; Hay J E; Rakela J; Wiesner R H; Krom R A
Orthotopic liver transplantation for preoperative early-stage hepatocellular carcinoma.
Mayo Clinic proceedings. Mayo Clinic 1994;69(6):509-14.
1994: Sandborn W J; Hay J E; Porayko M K; Gores G J; Steers J L; Krom R A; Wiesner R H
Cyclosporine withdrawal for nephrotoxicity in liver transplant recipients does not result in sustained improvement in kidney function and causes cellular and ductopenic rejection.
Hepatology (Baltimore, Md.) 1994;19(4):925-32.
1994: Porayko M K; Textor S C; Krom R A; Hay J E; Gores G J; Richards T M; Crotty P H; Beaver S J; Steers J L; Wiesner R H
Nephrotoxic effects of primary immunosuppression with FK-506 and cyclosporine regimens after liver transplantation.
Mayo Clinic proceedings. Mayo Clinic 1994;69(2):105-11.
1994: Nichols J C; Bronk S F; Mellgren R L; Gores G J
Inhibition of nonlysosomal calcium-dependent proteolysis by glycine during anoxic injury of rat hepatocytes.
Gastroenterology 1994;106(1):168-76.
1993: Rosser B G; Powers S P; Gores G J
Calpain activity increases in hepatocytes following addition of ATP. Demonstration by a novel fluorescent approach.
The Journal of biological chemistry 1993;268(31):23593-600.
1993: Nichols J C; Gores G J; LaRusso N F; Wiesner R H; Nagorney D M; Ritts R E
Diagnostic role of serum CA 19-9 for cholangiocarcinoma in patients with primary sclerosing cholangitis.
Mayo Clinic proceedings. Mayo Clinic 1993;68(9):874-9.
1993: Sanchez-Urdazpal L; Batts K P; Gores G J; Moore S B; Sterioff S; Wiesner R H; Krom R A
Increased bile duct complications in liver transplantation across the ABO barrier.
Annals of surgery 1993;218(2):152-8.
1993: Spivey J R; Bronk S F; Gores G J
Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium.
The Journal of clinical investigation 1993;92(1):17-24.
1993: Gores G J
Liver transplantation for malignant disease.
Gastroenterology clinics of North America 1993;22(2):285-99.
1993: Bronk S F; Powers S P; Gores G J
Dynamic measurements of intracellular aminopeptidase activity in hepatocytes using multiparameter digitized video fluorescent microscopy.
Analytical biochemistry 1993;210(2):219-25.
1993: Sanchez-Urdazpal L; Gores G J; Ward E M; Maus T P; Buckel E G; Steers J L; Wiesner R H; Krom R A
Diagnostic features and clinical outcome of ischemic-type biliary complications after liver transplantation.
Hepatology (Baltimore, Md.) 1993;17(4):605-9.
1993: Bronk S F; Gores G J
pH-dependent nonlysosomal proteolysis contributes to lethal anoxic injury of rat hepatocytes.
The American journal of physiology 1993;264(4 Pt 1):G744-51.
1993: Wiesner R H; Porayko M K; Wahlstrom H E; Gores G J; Kamath P S; Hay J E; Krom R A
Early cellular rejection treated with high-dose intravenous corticosteroid therapy is associated with a decrease in the incidence of steroid-resistant rejection and graft failure from rejection.
Transplantation proceedings 1993;25(2):1791-3.
1993: Ferguson D M; Gores G J; Bronk S F; Krom R A
An increase in cytosolic protease activity during liver preservation. Inhibition by glutathione and glycine.
Transplantation 1993;55(3):627-33.
1993: Sanchez-Urdazpal L; Gores G J; Lemasters J J; Thurman R G; Steers J L; Wahlstrom H E; Hay E I; Porayko M K; Wiesner R H; Krom R A
Carolina rinse solution decreases liver injury during clinical liver transplantation.
Transplantation proceedings 1993;25(1 Pt 2):1574-5.
1993: Sanchez-Urdazpal L; Gores G J; Ward E M; Hay E; Buckel E G; Wiesner R H; Krom R A
Clinical outcome of ischemic-type biliary complications after liver transplantation.
Transplantation proceedings 1993;25(1 Pt 2):1107-9.
1993: Porayko M K; Textor S C; Krom R A; Hay J E; Gores G J; Wahlstrom H E; Sanchez-Urdazpal L; Richards T; Crotty P; Beaver S
Nephrotoxicity of FK 506 and cyclosporine when used as primary immunosuppression in liver transplant recipients.
Transplantation proceedings 1993;25(1 Pt 1):665-8.
1992: Wiesner R H; Porayko M K; Dickson E R; Gores G J; LaRusso N F; Hay J E; Wahlstrom H E; Krom R A
Selection and timing of liver transplantation in primary biliary cirrhosis and primary sclerosing cholangitis.
Hepatology (Baltimore, Md.) 1992;16(5):1290-9.
1992: Kato A; Gores G J; LaRusso N F
Secretin stimulates exocytosis in isolated bile duct epithelial cells by a cyclic AMP-mediated mechanism.
The Journal of biological chemistry 1992;267(22):15523-9.
1992: Sanchez-Urdazpal L; Gores G J; Ward E M; Maus T P; Wahlstrom H E; Moore S B; Wiesner R H; Krom R A
Ischemic-type biliary complications after orthotopic liver transplantation.
Hepatology (Baltimore, Md.) 1992;16(1):49-53.
1992: Dickson R C; Bronk S F; Gores G J
Glycine cytoprotection during lethal hepatocellular injury from adenosine triphosphate depletion.
Gastroenterology 1992;102(6):2098-107.
1992: Spivey J R; Gores G J
Risk factors and screening for hepatocellular carcinoma.
Comprehensive therapy 1992;18(6):5-9.
1992: Groskreutz J L; Bronk S F; Gores G J
Ruthenium red delays the onset of cell death during oxidative stress of rat hepatocytes.
Gastroenterology 1992;102(3):1030-8.
1991: Sanchez-Urdazpal L; Gores G J; Ferguson D M; Krom R A
Improved liver preservation with addition of iloprost to Eurocollins and University of Wisconsin storage solutions.
Transplantation 1991;52(6):1105-7.
1991: Bronk S F; Gores G J
Efflux of protons from acidic vesicles contributes to cytosolic acidification of hepatocytes during ATP depletion.
Hepatology (Baltimore, Md.) 1991;14(4 Pt 1):626-33.
1991: Bronk S F; Gores G J
Acidosis protects against lethal oxidative injury of liver sinusoidal endothelial cells.
Hepatology (Baltimore, Md.) 1991;14(1):150-7.
1991: Wahlstrom H E; Cooper J; Gores G; Rosen C; Wiesner R; Krom R A
Survival after liver transplantation in diabetics.
Transplantation proceedings 1991;23(1 Pt 2):1565-6.
1991: Ferguson D M; Gores G J; Ludwig J; Krom R A
UW solution protects against reperfusion injury by inhibiting lipid peroxidation.
Transplantation proceedings 1991;23(1 Pt 2):1552-3.
1991: van Hoek B; Wiesner R H; Ludwig J; Gores G J; Moore B; Krom R A
Combination immunosuppression with azathioprine reduces the incidence of ductopenic rejection and vanishing bile duct syndrome after liver transplantation.
Transplantation proceedings 1991;23(1 Pt 2):1403-5.
1990: Kost L J; Gores G J; Sayles J M; Miller L J; Lemasters J J; Herman B; LaRusso N F
Lack of metabolic effects of cholecystokinin on hepatocytes.
Hepatology (Baltimore, Md.) 1990;12(2):301-5.
1989: Gores G J; Kost L J; Miller L J; LaRusso N F
Processing of cholecystokinin by isolated liver cells.
The American journal of physiology 1989;257(2 Pt 1):G242-8.
1987: Gores G J; Moore S B; Fisher L D; Powell F C; Dickson E R
Primary biliary cirrhosis: associations with class II major histocompatibility complex antigens.
Hepatology (Baltimore, Md.) 1987;7(5):889-92.

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