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Matthias Görlach

Research Profile

Procedures

Nuclear Magnetic Resonance, Biomolecular

Chemicals & Drugs

Concepts & Ideas

Phenomena

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
André Mischo; Oliver Ohlenschläger; Ramadurai Ramachandran; Matthias Görlach
NMR assignment of a PDZ domain in complex with a HPV51 E6 derived N-terminally pyroglutamic acid modified peptide.
André Mischo; Oliver Ohlenschläger; Ramadurai Ramachandran; Peter Hortschansky; Matthias Görlach
Structural insights into a wildtype domain of the oncoprotein E6 and its interaction with a PDZ domain.
Peter Bellstedt; Matthias Görlach; Sabine Häfner; Christian Herbst; Jörg Leppert; Ramadurai Ramachandran
Solid state NMR of proteins at high MAS frequencies: symmetry-based mixing and simultaneous acquisition of chemical shift correlation spectra.

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All Publications

2013: André Mischo; Oliver Ohlenschläger; Ramadurai Ramachandran; Matthias Görlach
NMR assignment of a PDZ domain in complex with a HPV51 E6 derived N-terminally pyroglutamic acid modified peptide.
Biomolecular NMR assignments 2013;7(1):47-9.
2013: André Mischo; Oliver Ohlenschläger; Ramadurai Ramachandran; Peter Hortschansky; Matthias Görlach
Structural insights into a wildtype domain of the oncoprotein E6 and its interaction with a PDZ domain.
PloS one 2013;8(4):e62584.
2012: Peter Bellstedt; Matthias Görlach; Sabine Häfner; Christian Herbst; Jörg Leppert; Ramadurai Ramachandran
Solid state NMR of proteins at high MAS frequencies: symmetry-based mixing and simultaneous acquisition of chemical shift correlation spectra.
Journal of biomolecular NMR 2012;54(4):325-35.
2012: Oliver Ohlenschläger; Hans-Peter Saluz; Annerose Schneider; Peter Bellstedt; Matthias Görlach; Frank Grosse; Frank Hänel; Sebastian Haumann; Peter Hortschansky; Heidi Keller; Anja Kuhnert; Helmut Pospiech
The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif.
Nucleic acids research 2012;40(17):8309-24.
2012: André Mischo; Oliver Ohlenschläger; Karl-Heinz Gührs; Matthias Görlach
Recombinant production of isotope-labeled peptides and spontaneous cyclization of amino-terminal glutamine into pyroglutamic acid.
Chembiochem : a European journal of chemical biology 2012;13(10):1421-3.
2012: Alesia A Tietze; Daniel Tietze; Florian Ullrich; Gerd Buntkowsky; Matthias Görlach; Stefan H Heinemann; Toni Kühl; Enrico Leipold; André Mischo; Oliver Ohlenschläger; Diana Imhof
Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4.
Angewandte Chemie (International ed. in English) 2012;51(17):4058-61.
2011: Christian Herbst; Jirada Herbst; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Chemical shift correlation at high MAS frequencies employing low-power symmetry-based mixing schemes.
Journal of biomolecular NMR 2011;50(3):277-84.
2010: Alesia Miloslavina; Christina Ebert; Daniel Tietze; Oliver Ohlenschläger; Christoph Englert; Matthias Görlach; Diana Imhof
An unusual peptide from Conus villepinii: synthesis, solution structure, and cardioactivity.
Peptides 2010;31(7):1292-300.
2010: Christian Herbst; Jirada Herbst; Michela Carella; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Broadband 15N-13C dipolar recoupling via symmetry-based RF pulse schemes at high MAS frequencies.
Journal of biomolecular NMR 2010;47(1):7-17.
2010: Michela Carella; Oliver Ohlenschläger; Ramadurai Ramachandran; Matthias Görlach
1H, 13C and 15N resonance assignment of a zinc-binding methionine sulfoxide reductase type-B from the thermophilic archeabacterium Methanothermobacter thermoautotrophicus.
Biomolecular NMR assignments 2010;4(1):93-5.
2009: Christian Herbst; Jirada Herbst; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Numerical design of RN(n)(nu) symmetry-based RF pulse schemes for recoupling and decoupling of nuclear spin interactions at high MAS frequencies.
Journal of biomolecular NMR 2009;44(4):235-44.
2009: Christian Herbst; Jirada Herbst; Anika Kirschstein; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Recoupling and decoupling of nuclear spin interactions at high MAS frequencies: numerical design of CN(n)(nu) symmetry-based RF pulse schemes.
Journal of biomolecular NMR 2009;44(4):175-84.
2009: Christian Herbst; Jirada Herbst; Anika Kirschstein; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Design of high-power, broadband 180 degrees pulses and mixing sequences for fast MAS solid state chemical shift correlation NMR spectroscopy.
Journal of biomolecular NMR 2009;43(1):51-61.
2008: Roland Zell; Yvonne Ihle; Madlen Effenberger; Simone Seitz; Peter Wutzler; Matthias Görlach
Interaction of poly(rC)-binding protein 2 domains KH1 and KH3 with coxsackievirus RNA.
Biochemical and biophysical research communications 2008;377(2):500-3.
2008: Oliver Ohlenschläger; Sebastian Haumann; Ramadurai Ramachandran; Matthias Görlach
Conformational signatures of 13C chemical shifts in RNA ribose.
Journal of biomolecular NMR 2008;42(2):139-42.
2008: Christian Herbst; Kerstin Riedel; Yvonne Ihle; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
MAS solid state NMR of RNAs with multiple receivers.
Journal of biomolecular NMR 2008;41(3):121-5.
2008: Anika Kirschstein; Christian Herbst; Kerstin Riedel; Michela Carella; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Heteronuclear J cross-polarisation in liquids using amplitude and phase modulated mixing sequences.
Journal of biomolecular NMR 2008;40(4):277-83.
2008: Anika Kirschstein; Christian Herbst; Kerstin Riedel; Michela Carella; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Broadband homonuclear TOCSY with amplitude and phase-modulated RF mixing schemes.
Journal of biomolecular NMR 2008;40(4):227-37.
2008: Roland Zell; Yvonne Ihle; Simone Seitz; Ulrike Gündel; Peter Wutzler; Matthias Görlach
Poly(rC)-binding protein 2 interacts with the oligo(rC) tract of coxsackievirus B3.
Biochemical and biophysical research communications 2008;366(4):917-21.
2007: Christian Herbst; Kerstin Riedel; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
13C-13C chemical shift correlation in rotating solids without 1H decoupling during mixing.
Chemphyschem : a European journal of chemical physics and physical chemistry 2007;8(12):1770-3.
2007: Kerstin Riedel; Christian Herbst; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Broadband homonuclear chemical shift correlation at high MAS frequencies: a study of tanh/tan adiabatic RF pulse schemes without 1H decoupling during mixing.
Journal of biomolecular NMR 2007;37(4):277-86.
2006: Oliver Ohlenschläger; T Seiboth; H Zengerling; L Briese; A Marchanka; R Ramachandran; M Baum; Malgorzata Korbas; W Meyer-Klaucke; M Dürst; Matthias Görlach
Solution structure of the partially folded high-risk human papilloma virus 45 oncoprotein E7.
Oncogene 2006;25(44):5953-9.
2006: Kerstin Riedel; Christian Herbst; Sabine Häfner; Jörg Leppert; Oliver Ohlenschläger; Maurice S Swanson; Matthias Görlach; Ramadurai Ramachandran
Constraints on the structure of (CUG)97 RNA from magic-angle-spinning solid-state NMR spectroscopy.
Angewandte Chemie (International ed. in English) 2006;45(34):5620-3.
2006: Kerstin Riedel; Christian Herbst; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Tailoring broadband inversion pulses for MAS solid state NMR.
Journal of biomolecular NMR 2006;35(4):275-83.
2006: Christian Herbst; Kerstin Riedel; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Solid state NMR at high magic angle spinning frequencies: dipolar chemical shift correlation with adiabatic inversion pulse based RF pulse schemes.
Journal of biomolecular NMR 2006;35(4):241-8.
2006: Domenica Musumeci; Margherita Valente; Domenica Capasso; Rosanna Palumbo; Matthias Görlach; Michaela Schmidtke; Roland Zell; Giovanni N Roviello; Roberto Sapio; Carlo Pedone; Enrico Bucci
A short PNA targeting coxsackievirus B3 5'-nontranslated region prevents virus-induced cytolysis.
Journal of peptide science : an official publication of the European Peptide Society 2006;12(3):161-70.
2005: Kerstin Riedel; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Characterisation of hydrogen bonding networks in RNAs via magic angle spinning solid state NMR spectroscopy.
Journal of biomolecular NMR 2005;31(4):331-6.
2005: Yvonne Ihle; Oliver Ohlenschläger; Sabine Häfner; Elke Duchardt; Martin Zacharias; Simone Seitz; Roland Zell; Ramadurai Ramachandran; Matthias Görlach
A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA.
Nucleic acids research 2005;33(6):2003-11.
2005: Kerstin Riedel; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
TEDOR with adiabatic inversion pulses: Resonance assignments of 13C/15N labelled RNAs.
Journal of biomolecular NMR 2005;31(1):49-57.
2004: Kerstin Riedel; Jörg Leppert; Sabine Häfner; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Homonuclear chemical shift correlation in rotating solids via RNnu n symmetry-based adiabatic RF pulse schemes.
Journal of biomolecular NMR 2004;30(4):389-95.
2004: Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Adiabatic heteronuclear decoupling in rotating solids.
Journal of biomolecular NMR 2004;29(3):319-24.
2004: Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Adiabatic TOBSY in rotating solids.
Journal of biomolecular NMR 2004;29(2):167-73.
2004: Roland Zell; René Markgraf; Michaela Schmidtke; Matthias Görlach; Axel Stelzner; Andreas Henke; Holger H Sigusch; Brigitte Glück
Nitric oxide donors inhibit the coxsackievirus B3 proteinases 2A and 3C in vitro, virus production in cells, and signs of myocarditis in virus-infected mice.
Medical microbiology and immunology 2004;193(2-3):91-100.
2004: Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
RFDR with adiabatic inversion pulses: application to internuclear distance measurements.
Journal of biomolecular NMR 2004;28(3):229-33.
2004: Elke Duchardt; Christian Richter; Oliver Ohlenschläger; Matthias Görlach; Jens Wöhnert; Harald Schwalbe
Determination of the glycosidic bond angle chi in RNA from cross-correlated relaxation of CH dipolar coupling and N chemical shift anisotropy.
Journal of the American Chemical Society 2004;126(7):1962-70.
2004: Oliver Ohlenschläger; Jens Wöhnert; Enrico Bucci; Simone Seitz; Sabine Häfner; Ramadurai Ramachandran; Roland Zell; Matthias Görlach
The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf RNA and its interaction with the proteinase 3C.
Structure (London, England : 1993) 2004;12(2):237-48.
2004: Jörg Leppert; Bert Heise; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Triple resonance MAS NMR with (13C, 15N) labelled molecules: reduced dimensionality data acquisition via 13C-15N heteronuclear two-spin coherence transfer pathways.
Journal of biomolecular NMR 2004;28(2):185-90.
2004: Jörg Leppert; Carl R Urbinati; Sabine Häfner; Oliver Ohlenschläger; Maurice S Swanson; Matthias Görlach; Ramadurai Ramachandran
Identification of NH...N hydrogen bonds by magic angle spinning solid state NMR in a double-stranded RNA associated with myotonic dystrophy.
Nucleic acids research 2004;32(3):1177-83.
2004: Matthias Stoldt; Eriks Kupce; Bernd H A Rehm; Matthias Görlach
Backbone resonance assignment of an aminoglycoside-3'-phosphotransferase type IIa.
Journal of biomolecular NMR 2004;28(1):93-4.
2004: Suisheng Zhang; Bernhard Schlott; Matthias Görlach; Frank Grosse
DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner.
Nucleic acids research 2004;32(1):1-10.
2003: Jens Wöhnert; Matthias Görlach; Harald Schwalbe
Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA applicable to larger RNA molecules.
Journal of biomolecular NMR 2003;26(1):79-83.
2003: Jörg Leppert; Bert Heise; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Broadband RFDR with adiabatic inversion pulses.
Journal of biomolecular NMR 2003;26(1):13-24.
2002: Bert Heise; Jörg Leppert; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
Chemical shift correlation via RFDR: elimination of resonance offset effects.
Journal of biomolecular NMR 2002;24(3):237-43.
2002: Jörg Leppert; Bert Heise; Matthias Görlach; Ramadurai Ramachandran
REDOR: an assessment of the efficacy of dipolar recoupling with adiabatic inversion pulses.
Journal of biomolecular NMR 2002;23(3):227-38.
2002: Oliver Ohlenschläger; Hironobu Hojo; Ramadurai Ramachandran; Matthias Görlach; Parvez I Haris
Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel.
Biophysical journal 2002;82(6):2995-3002.
2002: Bernhard Schlott; Jens Wöhnert; Christian Icke; Manfred Hartmann; Ramadurai Ramachandran; Karl-Heinz Gührs; Erika Glusa; Joachim Flemming; Matthias Görlach; Frank Grosse; Oliver Ohlenschläger
Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies.
Journal of molecular biology 2002;318(2):533-46.
2002: Roland Zell; Karim Sidigi; Enrico Bucci; Axel Stelzner; Matthias Görlach
Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C.
RNA (New York, N.Y.) 2002;8(2):188-201.
2002: Suisheng Zhang; Katrin Buder; Carmen Burkhardt; Bernhard Schlott; Matthias Görlach; Frank Grosse
Nuclear DNA helicase II/RNA helicase A binds to filamentous actin.
The Journal of biological chemistry 2002;277(1):843-53.
2001: Bert Heise; Jörg Leppert; H Wenschuh; Oliver Ohlenschläger; Matthias Görlach; Ramadurai Ramachandran
2D relayed anisotropy correlation NMR: characterization of the 13C' chemical shift tensor orientation in the peptide plane of the dipeptide AibAib.
Journal of biomolecular NMR 2001;19(2):167-79.
2000: Florian Mueller; I Sommer; Pavel Baranov; R Matadeen; Matthias Stoldt; Jens Wöhnert; Matthias Görlach; Marin van Heel; Richard Brimacombe
The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution.
Journal of molecular biology 2000;298(1):35-59.
1999: Matthias Stoldt; Jens Wöhnert; Oliver Ohlenschläger; Matthias Görlach; LR Brown
The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition.
The EMBO journal 1999;18(22):6508-21.
1999: Jens Wöhnert; Andrew J Dingley; Matthias Stoldt; Matthias Görlach; Stephan Grzesiek; LR Brown
Direct identification of NH...N hydrogen bonds in non-canonical base pairs of RNA by NMR spectroscopy.
Nucleic acids research 1999;27(15):3104-10.
1999: Jens Wöhnert; Ramadurai Ramachandran; Matthias Görlach; LR Brown
Triple-resonance experiments for correlation of H5 and exchangeable pyrimidine base hydrogens in (13)C,(15)N-labeled RNA.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1999;139(2):430-3.
1998: Matthias Stoldt; Jens Wöhnert; Matthias Görlach; LR Brown
The NMR structure of Escherichia coli ribosomal protein L25 shows homology to general stress proteins and glutaminyl-tRNA synthetases.
The EMBO journal 1998;17(21):6377-84.
1997: C Sich; Oliver Ohlenschläger; Ramadurai Ramachandran; Matthias Görlach; LR Brown
Structure of an RNA hairpin loop with a 5'-CGUUUCG-3' loop motif by heteronuclear NMR spectroscopy and distance geometry.
Biochemistry 1997;36(46):13989-4002.
1997: H Ottleben; M Haasemann; Ramadurai Ramachandran; Matthias Görlach; W Müller-Esterl; LR Brown
An NMR study of the interaction of 15N-labelled bradykinin with an antibody mimic of the bradykinin B2 receptor.
European journal of biochemistry / FEBS 1997;244(2):471-8.
1996: M Grüne; Matthias Görlach; Vukic Soskic; S Klussmann; Rolf Bald; Jens P Fürste; Volker A Erdmann; LR Brown
Initial analysis of 750 MHz NMR spectra of selective 15N-G,U labelled E. coli 5S rRNA.
FEBS letters 1996;385(1-2):114-8.