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Jaime Gosálvez

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Procedures

Anatomy

Physiology

DNA Fragmentation

Disorders

DNA Damage

Chemicals & Drugs

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Elva I Cortés-Gutiérrez; Martha I Dávila-Rodríguez; José Luis Fernández; Carmen López-Fernández; Cerda-Flores Ricardo M; Brenda L Ortíz-Hernández; Jaime Gosálvez
5-bp Classical Satellite DNA Loci from Chromosome-1 Instability in Cervical Neoplasia Detected by DNA Breakage Detection/Fluorescence in Situ Hybridization (DBD-FISH).
María Tamayo; Germán Bou; María Del Cármen Fernández; Jaime Gosálvez; Rebeca Santiso; José Luis Fernández
Cell wall active antibiotics reduce chromosomal DNA fragmentation by peptidoglycan hydrolysis in Staphylococcus aureus.
Rocio Nuñez-Calonge; Pedro Caballero; José Luís Fernández; J Andrés Guijarro; Stephen Johnston; Carmen López-Fernández; Jaime Gosálvez
An improved experimental model for understanding the impact of sperm DNA fragmentation on human pregnancy following ICSI.

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2013: Elva I Cortés-Gutiérrez; Martha I Dávila-Rodríguez; José Luis Fernández; Carmen López-Fernández; Cerda-Flores Ricardo M; Brenda L Ortíz-Hernández; Jaime Gosálvez
5-bp Classical Satellite DNA Loci from Chromosome-1 Instability in Cervical Neoplasia Detected by DNA Breakage Detection/Fluorescence in Situ Hybridization (DBD-FISH).
International journal of molecular sciences 2013;14(2):4135-47.
2012: María Tamayo; Germán Bou; María Del Cármen Fernández; Jaime Gosálvez; Rebeca Santiso; José Luis Fernández
Cell wall active antibiotics reduce chromosomal DNA fragmentation by peptidoglycan hydrolysis in Staphylococcus aureus.
Archives of microbiology 2012;194(12):967-75.
2012: Rocio Nuñez-Calonge; Pedro Caballero; José Luís Fernández; J Andrés Guijarro; Stephen Johnston; Carmen López-Fernández; Jaime Gosálvez
An improved experimental model for understanding the impact of sperm DNA fragmentation on human pregnancy following ICSI.
Reproductive sciences (Thousand Oaks, Calif.) 2012;19(11):1163-8.
2012: Germán Bou; María del Carmen Fernández; Jaime Gosálvez; Fátima María Otero; Rebeca Santiso; María Tamayo; María Tomás; José Luis Fernández
Fast assessment of resistance to carbapenems and ciprofloxacin of clinical strains of Acinetobacter baumannii.
Journal of clinical microbiology 2012;50(11):3609-13.
2012: Stephen D Johnston; Carmen López-Fernández; N Satake; Y Zee; William V Holt; Jaime Gosálvez
Osmotic stress and cryoinjury of koala sperm: an integrative study of the plasma membrane, chromatin stability and mitochondrial function.
Reproduction (Cambridge, England) 2012;143(6):787-97.
2012: Rebeca Santiso; María Tamayo; Carlos Fernández; Jaime Gosálvez; Steve Johnston; Carlos Losada; Alfonso Mariño; José Luis Fernández
DNA fragmentation dynamics allows the assessment of cryptic sperm damage in human: evaluation of exposure to ionizing radiation, hyperthermia, acidic pH and nitric oxide.
Mutation research 2012;734(1-2):41-9.
2012: Luna Gutiérrez-Cepeda; Miguel Ángel Ramírez; Francisco Crespo; Alvaro Fernández; Jaime Gosálvez; Consuelo Serres
The effect of two pre-cryopreservation single layer colloidal centrifugation protocols in combination with different freezing extenders on the fragmentation dynamics of thawed equine sperm DNA.
Acta veterinaria Scandinavica 2012;54():72.
2012: Clara González-Marín; Jaime Gosálvez; Rosa Roy
Types, causes, detection and repair of DNA fragmentation in animal and human sperm cells.
International journal of molecular sciences 2012;13(11):14026-52.
2011: Jaime Gosálvez; Anne Gouraud; José L Fernández; Carmen López-Fernández; William V Holt
Relationships between the dynamics of iatrogenic DNA damage and genomic design in mammalian spermatozoa from eleven species.
Molecular reproduction and development 2011;78(12):951-61.
2011: A García-Peiró; Jaime Gosálvez; M Guitart; J Navarro; Maria Oliver-Bonet; C Abad; M J Amengual; J Benet
Dynamics of sperm DNA fragmentation in patients carrying structurally rearranged chromosomes.
International journal of andrology 2011;34(6 Pt 2):e546-53.
2011: Jaime Gosálvez; Carmen López-Fernández; José L Fernández; Mercedes González-Martínez; Pascual Sánchez-Martín
Shorter abstinence decreases sperm deoxyribonucleic acid fragmentation in ejaculate.
Fertility and sterility 2011;96(5):1083-6.
2011: Maria Enciso; Isabel Galán; Antonio Gosálvez; Miriam Iglesias; Jonás Sarasa; Jaime Gosálvez
The ability of sperm selection techniques to remove single- or double-strand DNA damage.
Asian journal of andrology 2011;13(5):764-8.
2011: Elva I Cortés-Gutiérrez; Martha I Dávila-Rodríguez; José Luís Fernández; Altea Gosálbez; Carmen López-Fernández; Jaime Gosálvez
New application of the comet assay: chromosome--comet assay.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2011;59(7):655-60.
2011: Elva I Cortés-Gutiérrez; Martha I Dávila-Rodríguez; José Luís Fernandez; Carmen López-Fernández; Jaime Gosálvez
DNA damage in women with cervical neoplasia evaluated by DNA breakage detection-fluorescence in situ hybridization.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 2011;33(3):175-81.
2011: C González-Marín; R Roy; Carmen López-Fernández; B Diez; M J Carabaño; José Luis Fernández; M E Kjelland; J F Moreno; Jaime Gosálvez
Bacteria in bovine semen can increase sperm DNA fragmentation rates: a kinetic experimental approach.
Animal reproduction science 2011;123(3-4):139-48.
2011: Jaime Gosálvez; M A Ramirez; Carmen López-Fernández; F Crespo; K M Evans; M E Kjelland; J F Moreno
Sex-sorted bovine spermatozoa and DNA damage: II. Dynamic features.
Theriogenology 2011;75(2):206-11.
2011: Jaime Gosálvez; M A Ramirez; Carmen López-Fernández; F Crespo; K M Evans; M E Kjelland; J F Moreno
Sex-sorted bovine spermatozoa and DNA damage: I. Static features.
Theriogenology 2011;75(2):197-205.
2011: Martha I Dávila-Rodríguez; J L Fernández; Ricardo M Cerda-Flores; E I Cortés Gutiérrez; Carmen López-Fernández; M Pita; Jaime Gosálvez
Constitutive heterochromatin polymorphisms in human chromosomes identified by whole comparative genomic hybridization.
European journal of histochemistry : EJH 2011;55(3):e28.
2011: María Enciso; Stephen D Johnston; Jaime Gosálvez
Differential resistance of mammalian sperm chromatin to oxidative stress as assessed by a two-tailed comet assay.
Reproduction, fertility, and development 2011;23(5):633-7.
2010: Carmen López-Fernández; Stephen D Johnston; José Luis Fernández; R J Wilson; Jaime Gosálvez
Fragmentation dynamics of frozen-thawed ram sperm DNA is modulated by sperm concentration.
Theriogenology 2010;74(8):1362-70.
2010: Jaime Gosálvez; Joaquina de la Torre; Carmen López-Fernández; Laura Pérez-Gutiérrez; Leonor Ortega; Pedro Caballero; Rocio Nuñez
DNA fragmentation dynamics in fresh versus frozen thawed plus gradient-isolated human spermatozoa.
Systems biology in reproductive medicine 2010;56(1):27-36.
2009: Jaime Gosálvez; Elva I Cortés-Gutiérrez; Rocio Nuñez; José Luis Fernández; Pedro Caballero; Carmen López-Fernández; William V Holt
A dynamic assessment of sperm DNA fragmentation versus sperm viability in proven fertile human donors.
Fertility and sterility 2009;92(6):1915-9.
2009: Carmen López-Fernández; Matthew J G Gage; Francisca Arroyo; Altea Gosálbez; Ana M Larrán; José Luis Fernández; Jaime Gosálvez
Rapid rates of sperm DNA damage after activation in tench (Tinca tinca: Teleostei, Cyprinidae) measured using a sperm chromatin dispersion test.
Reproduction (Cambridge, England) 2009;138(2):257-66.
2009: Jaime Gosálvez; Elva Cortés-Gutierez; Carmen López-Fernández; José Luis Fernández; Pedro Caballero; Rocio Nuñez
Sperm deoxyribonucleic acid fragmentation dynamics in fertile donors.
Fertility and sterility 2009;92(1):170-3.
2009: Maria Enciso; Jonas Sarasa; Ashok Agarwal; Jose Luis Fernández; Jaime Gosálvez
A two-tailed Comet assay for assessing DNA damage in spermatozoa.
Reproductive biomedicine online 2009;18(5):609-16.
2009: Miguel Pita; Jaime Gosálvez; A Gosálvez; M Nieddu; C López-Fernández; R Mezzanotte
A highly conserved pericentromeric domain in human and gorilla chromosomes.
Cytogenetic and genome research 2009;126(3):253-8.
2009: Stephen D Johnston; Carmen López-Fernández; Altea Gosálbez; William V Holt; Jaime Gosálvez
Directional mapping of DNA nicking in ejaculated and cauda epididymidal spermatozoa of the short-beaked echidna (Tachyglossus aculeatus: Monotremata).
Reproduction, fertility, and development 2009;21(8):1008-14.
2008: José Luis Fernández; Mónica Cartelle; Lourdes Muriel; Rebeca Santiso; María Tamayo; Vicente Goyanes; Jaime Gosálvez; Germán Bou
DNA fragmentation in microorganisms assessed in situ.
Applied and environmental microbiology 2008;74(19):5925-33.
2008: Carmen López-Fernández; José Luis Fernández; Altea Gosálbez; Francisca Arroyo; J M Vázquez; William V Holt; Jaime Gosálvez
Dynamics of sperm DNA fragmentation in domestic animals III. Ram.
Theriogenology 2008;70(6):898-908.
2008: Guadalupe Gallegos; Benito Ramos; Rebeca Santiso; Vicente Goyanes; Jaime Gosálvez; José Luis Fernández
Sperm DNA fragmentation in infertile men with genitourinary infection by Chlamydia trachomatis and Mycoplasma.
Fertility and sterility 2008;90(2):328-34.
2008: Elva I Cortés-Gutiérrez; Martha I Dávila-Rodríguez; Carmen López-Fernández; José Luis Fernández; Jaime Gosálvez
Alkali-labile sites in sperm cells from Sus and Ovis species.
International journal of andrology 2008;31(3):354-63.
2008: Adriana Cerná; Carmen López-Fernández; José Luis Fernández; Susana Moreno Díaz de la Espina; Consuelo De la Torre; Jaime Gosálvez
Triplex configuration in the nick-free DNAs that constitute the chromosomal scaffolds in grasshopper spermatids.
Chromosoma 2008;117(1):15-24.
2008: Carmen López-Fernández; Begoña Pérez-Llano; Pedro García-Casado; R Sala; Altea Gosálbez; Francisca Arroyo; José Luis Fernández; Jaime Gosálvez
Sperm DNA fragmentation in a random sample of the Spanish boar livestock.
Animal reproduction science 2008;103(1-2):87-98.
2008: Miguel Pita; M Zabal-Aguirre; Francisca Arroyo; Jaime Gosálvez; Carmen López-Fernández; Joaquina de la Torre
Arcyptera fusca and Arcyptera tornosi repetitive DNA families: whole-comparative genomic hybridization (W-CGH) as a novel approach to the study of satellite DNA libraries.
Journal of evolutionary biology 2008;21(1):352-61.
2007: Carmen López-Fernández; F Crespo; Francisca Arroyo; José Luis Fernández; P Arana; Stephen D Johnston; Jaime Gosálvez
Dynamics of sperm DNA fragmentation in domestic animals II. The stallion.
Theriogenology 2007;68(9):1240-50.
2007: Stephen D Johnston; Carmen López-Fernández; Altea Gosálbez; Yengpeng Zee; William V Holt; Camryn Allen; Jaime Gosálvez
The relationship between sperm morphology and chromatin integrity in the koala (Phascolarctos cinereus) as assessed by the Sperm Chromatin Dispersion test (SCDt).
Journal of andrology 2007;28(6):891-9.
2007: Joaquina de la Torre; Carmen López-Fernández; Miguel Pita; José Luis Fernández; Stephen D Johnston; Jaime Gosálvez
Simultaneous observation of DNA fragmentation and protein loss in the boar spermatozoon following application of the sperm chromatin dispersion (SCD) test.
Journal of andrology 2007;28(4):533-40.
2007: Miguel Pita; José Luis Fernández; Jaime Gosálvez
Whole-comparative genomic hybridization and "cell code" estimation: an application for assessment of cellular chimerism.
European journal of medical research 2007;12(5):206-11.
2007: Carmen López-Fernández; A Baltanás; Joaquina de la Torre; Jaime Gosálvez
Drosophila melanogaster and Eucypris virens giant spermatozoa as visualized by cell inclusion in microgels.
Journal of experimental zoology. Part A, Ecological genetics and physiology 2007;307(3):140-4.
2007: Elva I Cortés-Gutiérrez; Martha I Dávila-Rodríguez; Carmen López-Fernández; J L Fernández; Jaime Gosálvez
[Assessing sperm DNA damage].
Actas urologicas españolas 2007;31(2):120-31.
2007: Rebeca Santiso; Lourdes Muriel; Vicente Goyanes; Enrique Segrelles; Jaime Gosálvez; José Luis Fernández
Evidence of modified nuclear protein matrix in human spermatozoa with fragmented deoxyribonucleic acid.
Fertility and sterility 2007;87(1):191-4.
2007: Lourdes Muriel; Vicente Goyanes; Enrique Segrelles; Jaime Gosálvez; Juan G Alvarez; José Luis Fernández
Increased aneuploidy rate in sperm with fragmented DNA as determined by the sperm chromatin dispersion (SCD) test and FISH analysis.
Journal of andrology 2007;28(1):38-49.
2006: Begoña Pérez-Llano; Maria Enciso; Pedro García-Casado; Rubén Sala; Jaime Gosálvez
Sperm DNA fragmentation in boars is delayed or abolished by using sperm extenders.
Theriogenology 2006;66(9):2137-43.
2006: Carmen López-Fernández; Francisca Arroyo; José Luis Fernández; Jaime Gosálvez
Interstitial telomeric sequence blocks in constitutive pericentromeric heterochromatin from Pyrgomorpha conica (Orthoptera) are enriched in constitutive alkali-labile sites.
Mutation research 2006;599(1-2):36-44.
2006: Maria Enciso; Carmen López-Fernández; José Luis Fernández; Pedro García; Altea Gosálbez; Jaime Gosálvez
A new method to analyze boar sperm DNA fragmentation under bright-field or fluorescence microscopy.
Theriogenology 2006;65(2):308-16.
2006: Maria Enciso; Lourdes Muriel; José Luis Fernández; Vicente Goyanes; Enrique Segrelles; Mercedes Marcos; Juan Manuel Montejo; Manolo Ardoy; Alberto Pacheco; Jaime Gosálvez
Infertile men with varicocele show a high relative proportion of sperm cells with intense nuclear damage level, evidenced by the sperm chromatin dispersion test.
Journal of andrology 2006;27(1):106-11.
2005: José Luis Fernández; Lourdes Muriel; Vicente Goyanes; Enrique Segrelles; Jaime Gosálvez; Maria Enciso; Marie LaFromboise; Christopher De Jonge
Halosperm is an easy, available, and cost-effective alternative for determining sperm DNA fragmentation.
Fertility and sterility 2005;84(4):860.
2005: Silvia Rodríguez; Vicente Goyanes; Enrique Segrelles; María Blasco; Jaime Gosálvez; José Luis Fernández
Critically short telomeres are associated with sperm DNA fragmentation.
Fertility and sterility 2005;84(4):843-5.
2005: José Luis Fernández; Lourdes Muriel; Vicente Goyanes; Enrique Segrelles; Jaime Gosálvez; Maria Enciso; Marie LaFromboise; Christopher De Jonge
Simple determination of human sperm DNA fragmentation with an improved sperm chromatin dispersion test.
Fertility and sterility 2005;84(4):833-42.
2005: Alejandro Mosquera; Jaime Gosálvez; Laure Sabatier; José Luis Fernández
Interstitial telomeric DNA sequences of Chinese hamster cells are hypersensitive to nitric oxide damage, and DNA-PKcs has a specific local role in its repair.
Genes, chromosomes & cancer 2005;44(1):76-84.
2004: Carmen López-Fernández; E Pradillo; M Zabal-Aguirre; José Luis Fernández; C García de la Vega; Jaime Gosálvez
Telomeric and interstitial telomeric-like DNA sequences in Orthoptera genomes.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2004;47(4):757-63.
2004: Lourdes Muriel; Enrique Segrelles; Vicente Goyanes; Jaime Gosálvez; José Luis Fernández
Structure of human sperm DNA and background damage, analysed by in situ enzymatic treatment and digital image analysis.
Molecular human reproduction 2004;10(3):203-9.
2004: Francisco Perfectti; Miguel Pita; C G de la Vega; Jaime Gosálvez; J P M Camacho
Spatio-temporal dynamics of a neutralized B chromosome in the grasshopper Eyprepocnemis plorans.
Cytogenetic and genome research 2004;106(2-4):376-85.
2003: Jaime Gosálvez; Nuria Ortiz-Movilla; Altea Gosálbez; Elena Rodríguez-Iñigo; Javier Bartolomé; Vicente Carreño
Improved sensitivity for cell mapping of hepatitis C virus RNA sequences and cellular surface antigens in blood cells.
Laboratory investigation; a journal of technical methods and pathology 2003;83(7):1089-91.
2003: Miguel Pita; José Luis Fernandez; Jaime Gosálvez
Whole-comparative genomic hybridization (W-CGH): 1. The quick overview of repetitive DNA sequences on a genome.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2003;11(7):673-9.
2003: María Teresa Rivero; Fernando Vázquez-Gundín; Lourdes Muriel; Vicente Goyanes; Jaime Gosálvez; José Luis Fernández
Patterns of DNA migration in two-dimensional single-cell gel electrophoresis analyzed by DNA breakage detection-fluorescence in situ hybridization.
Environmental and molecular mutagenesis 2003;42(3):223-7.
2002: Fernando Vázquez-Gundín; María Teresa Rivero; Jaime Gosálvez; José Luis Fernández
Radiation-induced DNA breaks in different human satellite DNA sequence areas, analyzed by DNA breakage detection-fluorescence in situ hybridization.
Radiation research 2002;157(6):711-20.
2002: Jon R Bridle; Joaquina de la Torre; José L Bella; Roger K Butlin; Jaime Gosálvez
Low levels of chromosomal differentiation between the grasshoppers Chorthippus brunneus and Chorthippusjacobsi (Orthoptera; Acrididae) in northern Spain.
Genetica 2002;114(2):121-7.
2002: José Luis Fernández; Jaime Gosálvez
Application of FISH to detect DNA damage. DNA breakage detection-FISH (DBD-FISH).
Methods in molecular biology (Clifton, N.J.) 2002;203():203-16.
2002: Jaime Gosálvez; Joaquina de la Torre; Miguel Pita; A Martinez-Ramirez; C López-Fernandez; Vicente Goyanes; J López-Fernández
FISHing in the microwave: the easy way to preserve proteins. I. Colocalization of DNA probes and surface antigens in human leukocytes.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2002;10(2):137-43.
2001: María Teresa Rivero; Fernando Vázquez-Gundín; Vicente Goyanes; A Campos; M Blasco; Jaime Gosálvez; José Luis Fernández
High frequency of constitutive alkali-labile sites in mouse major satellite DNA, detected by DNA breakage detection-fluorescence in situ hybridization.
Mutation research 2001;483(1-2):43-50.
2001: José Luis Fernández; Fernando Vázquez-Gundín; María Teresa Rivero; A Genescá; Jaime Gosálvez; Vicente Goyanes
DBD-fish on neutral comets: simultaneous analysis of DNA single- and double-strand breaks in individual cells.
Experimental cell research 2001;270(1):102-9.
2001: José Luis Fernández; Fernando Vázquez-Gundín; María Teresa Rivero; Vicente Goyanes; Jaime Gosálvez
Evidence of abundant constitutive alkali-labile sites in human 5 bp classical satellite DNA loci by DBD-FISH.
Mutation research 2001;473(2):163-8.
2001: Ismael Buño; José Luis Fernández; Carmen López-Fernández; José L Díez-Martín; Jaime Gosálvez
Sau3A in situ digestion of human chromosome 3 pericentrometric heterochromatin. I. Differential digestion of alpha-satellite and satellite 1 DNA sequences.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2001;44(1):120-7.
2000: Fernando Vázquez-Gundín; Jaime Gosálvez; J de la Torre; José Luis Fernández
DNA breakage detection-fish (DBD-FISH): effect of unwinding time.
Mutation research 2000;453(1):83-8.
2000: José Luis Fernández; Fernando Vázquez-Gundín; A Delgado; Vicente Goyanes; JL Ramiro-Díaz; J de la Torre; Jaime Gosálvez
DNA breakage detection-FISH (DBD-FISH) in human spermatozoa: technical variants evidence different structural features.
Mutation research 2000;453(1):77-82.
2000: Joaquina de la Torre; Angel Martínez-Ramírez; José Luis Fernández; José L Díez-Martín; Alfonso Gómez-Pineda; Jaime Gosálvez; Carmen López-Fernández
A PCR product derived from female DNA with regional localization on the Y chromosome.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2000;43(3):580-3.
2000: Elsa Pinna-Senn; José A Lisanti; M I Ortiz; G Dalmasso; José L Bella; Jaime Gosálvez; Juan C Stockert
Specific heterochromatic banding of metaphase chromosomes using nuclear yellow.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2000;75(3):132-40.
2000: José L Díez-Martín; Ismael Buño; P Llamas; Jaime Gosálvez; Carmen López-Fernández; N Polo; C Regidor
Fluorescence in situ hybridization evaluation of minimal residual disease on stem-cell harvests.
Cancer detection and prevention 2000;24(2):169-72.
1999: Ismael Buño; Joaquina de la Torre; E Torroja; José Luis Fernández; Carmen López-Fernández; José L Díez-Martín; Jaime Gosálvez
Chimerism quantification after sex-matched BMT: how probable is it to find donor/recipient pairs with distinguishable cells?
Cancer genetics and cytogenetics 1999;113(2):152-5.
1999: Alejandro Mosquera; J L Fernández; A Campos; Vicente Goyanes; JL Ramiro-Díaz; Jaime Gosálvez
Simultaneous decrease of telomere length and telomerase activity with ageing of human amniotic fluid cells.
Journal of medical genetics 1999;36(6):494-6.
1999: Elena Rodríguez-Iñigo; Javier Bartolomé; Susana de Lucas; Félix Manzarbeitia; Margarita Pardo; C Arocena; Jaime Gosálvez; Horacio Oliva; Vicente Carreño
Histological damage in chronic hepatitis C is not related to the extent of infection in the liver.
The American journal of pathology 1999;154(6):1877-81.
1999: Ismael Buño; José L Díez-Martín; Carmen López-Fernández; José Luis Fernández; Jaime Gosálvez
Polymorphisms for the size of heterochromatic regions allow sex-independent quantification of post-BMT chimerism targeting metaphase and interphase cells.
Haematologica 1999;84(2):138-41.
1998: José L Díez-Martín; P Llamas; Jaime Gosálvez; Carmen López-Fernández; N Polo; M S de la Fuente; Ismael Buño
Conventional cytogenetics and FISH evaluation of chimerism after sex-mismatched bone marrow transplantation (BMT) and donor leukocyte infusion (DLI).
Haematologica 1998;83(5):408-15.
1998: Jaime Gosálvez; Elena Rodríguez-Iñigo; JL Ramiro-Díaz; Javier Bartolomé; José F Tomás; Horacio Oliva; Vicente Carreño
Relative quantification and mapping of hepatitis C virus by in situ hybridization and digital image analysis.
Hepatology (Baltimore, Md.) 1998;27(5):1428-34.
1998: José Luis Fernández; Vicente Goyanes; JL Ramiro-Díaz; Jaime Gosálvez
Application of FISH for in situ detection and quantification of DNA breakage.
Cytogenetics and cell genetics 1998;82(3-4):251-6.
1998: José Luis Fernández; Vicente Goyanes; JL Ramiro-Díaz; Jaime Gosálvez
Evidence of a differential organization of chromatin containing terminal or interstitial (TTAGGG)n repeats by in situ digestion with nucleases.
Cytogenetics and cell genetics 1998;82(3-4):195-8.
1997: Jaime Gosálvez; Ismael Buño; Carmen López-Fernández; José Luis Fernández; Vicente Goyanes
Image analysis of murine chromatin fiber structure after in situ digestion with restriction endonucleases.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1997;19(3):207-14.
1997: Ismael Buño; Carmen López-Fernández; José L Díez-Martín; Jaime Gosálvez
Dynamics of Sau3A in situ digestion of human chromosomes analyzed with computerized imaging.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1997;40(1):123-6.
1997: José Luis Fernández; Diana Valverde; Vicente Goyanes; Ismael Buño; Jaime Gosálvez
AluI in situ digestion of human alphoid and classical satellite DNA regions: high-resolution digital image analysis of FISH signals from condensed and extended chromatin.
Cytogenetics and cell genetics 1997;76(1-2):94-100.
1996: José Luis Fernández; Carmen López-Fernández; Jaime Gosálvez; Vicente Goyanes
Differential sensitivity of some human alphoid and classical satellite DNA regions from lymphocyte chromosomes to in situ exonuclease III digestion.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1996;39(6):1210-3.
1996: José L Díez-Martín; Ismael Buño; Carmen López-Fernández; Manuel-Nicolás Fernández; N Polo; Jaime Gosálvez
Restriction endonuclease in situ digestion (REISD): a novel quantitative sex-independent method to analyze chimerism after bone marrow transplantation.
Experimental hematology 1996;24(11):1333-9.
1996: Jaime Gosálvez; Carmen López-Fernández; Ismael Buño; N Polo; Pilar Llamas; Manuel-Nicolás Fernández; José Luis Fernández; José L Díez-Martín
Restriction endonuclease in situ digestion (REISD) and fluorescence in situ hybridization (FISH) as complementary methods to analyze chimerism and residual disease after bone marrow transplantation.
Cancer genetics and cytogenetics 1996;89(2):141-5.
1996: Ismael Buño; Carmen López-Fernández; José Luis Fernández; Pilar Llamas; J L Díez-Martin; Jaime Gosálvez
Improving chimaerism quantification in bone marrow transplant recipients by image processing and analysis after restriction endonuclease in situ digestion (IPA-REISD).
Leukemia 1996;10(7):1232-6.
1996: Jaime Gosálvez; Carmen López-Fernández; José Luis Fernández; Vicente Goyanes; Ismael Buño
Digital image analysis of chromatin fibre phenotype after "in situ' digestion with restriction endonucleases.
Cell biology international 1996;20(3):213-7.
1996: José Luis Fernández; Diana Valverde; Jaime Gosálvez; C Pineiro; S Pereira; Vicente Goyanes
Chromosome fragments with alphoid sequences derived from a pseudoisodicentric Y chromosome.
Journal of medical genetics 1996;33(1):84-6.
1996: J de la Torre; P Herrero; C G de la Vega; A T Sumner; Jaime Gosálvez
Patterns of DNase I sensitivity in the chromosomes of the grasshopper Chorthippus parallelus (Orthoptera).
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1996;4(1):56-60.
1996: José Luis Fernández; Vicente Goyanes; Carmen López-Fernández; Ismael Buño; Jaime Gosálvez
Quantification of C-ERB-B2 gene amplification in breast cancer cells using fluorescence in situ hybridization and digital image analysis.
Cancer genetics and cytogenetics 1996;86(1):18-21.
1995: J L Bella; José Luis Fernández; Jaime Gosálvez
C-banding plus fluorochrome staining shows differences in C-, G-, and R-bands in human and mouse metaphase chromosomes.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1995;38(5):864-8.
1995: Jaime Gosálvez; Carmen López-Fernández; José Luis Fernández; Vicente Goyanes; Ismael Buño
Digital image analysis of chromatin fibre phenotype after "in situ" digestion with restriction endonucleases.
Cell biology international 1995;19(10):827-32.
1995: José Luis Fernández; Jaime Gosálvez; Vicente Goyanes
High frequency of mutagen-induced chromatid exchanges at interstitial telomere-like DNA sequence blocks of Chinese hamster cells.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1995;3(5):281-4.
1995: José Luis Fernández; A Campos; Carmen López-Fernández; Jaime Gosálvez; Vicente Goyanes
Difference in constitutive heterochromatin behaviour between human amniocytes and lymphocytes detected by a sequential in situ exonuclease III digestion-random primer extension procedure.
Journal of medical genetics 1995;32(1):32-5.
1994: J L Bella; Jaime Gosálvez
Banding human chromosomes using a combined C-banding-fluorochrome staining technique.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 1994;69(5):243-8.
1994: José Luis Fernández; S Pereira; A Campos; Jaime Gosálvez; Vicente Goyanes
An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin.
Journal of medical genetics 1994;31(8):632-4.
1994: José Luis Fernández; A Campos; Vicente Goyanes; Ismael Buño; Jaime Gosálvez
Sister chromatid differentiation after in situ detection of ultraviolet-induced DNA breaks under electron microscopy.
Biology of the cell / under the auspices of the European Cell Biology Organization 1994;82(1):33-7.
1994: José Luis Fernández; Vicente Goyanes; Carmen López-Fernández; Jaime Gosálvez
Human alpha-satellite DNAs are not susceptible to undercondensation after 5-azacytidine treatment.
Cytogenetics and cell genetics 1994;65(1-2):92-4.
1994: José Luis Fernández; Vicente Goyanes; S Pereira; Carmen López-Fernández; Jaime Gosálvez
5-azacytidine produces differential undercondensation of alpha, beta and classical human satellite DNAs.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 1994;2(1):29-35.
1993: Jaime Gosálvez; Carmen López-Fernández; José Luis Fernández; Vicente Goyanes
Oligonucleotide priming in situ to detect induced DNA breaks under electron microscopy.
Trends in genetics : TIG 1993;9(5):156-7.
1993: Jaime Gosálvez; Carmen López-Fernández; C García de la Vega; R Mezzanotte; José Luis Fernández; Vicente Goyanes
Selective digestion of mouse chromosomes with restriction endonucleases. Oligonucleotide priming of single-stranded DNA produced with exonuclease III.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1993;36(2):230-4.
1993: José Luis Fernández; Jaime Gosálvez; Vicente Goyanes
Detection of DNA strand breaks induced by hydroxyl radicals in nuclear and chromosomal chromatin by electron microscopy.
Cytobios 1993;73(294-295):189-95.
1992: P Herrero; J de la Torre; Jaime Gosálvez; A T Sumner
Heterochromatin characterization of sex chromosomes in Triturus marmoratus (Urodela, Salamandridae).
Cytogenetics and cell genetics 1992;60(2):150-3.
1991: T Cuéllar; Jaime Gosálvez; P Del Castillo; Juan C Stockert
Fluram induces species-dependent C and G bands in mammalian chromosomes, revealing heterogeneous distribution of chromosomal proteins.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1991;34(5):772-6.
1991: Juan C Stockert; Jaime Gosálvez; P Del Castillo; C Pelling; R Mezzanotte
X-ray microanalysis of toluidine blue stained chromosomes: a quantitative study of the metachromatic reaction of chromatin.
Histochemistry 1991;95(3):289-95.
1991: Jaime Gosálvez; R Mezzanotte; Carmen López-Fernández; P Del Castillo; Juan C Stockert; Vicente Goyanes; A T Sumner
Selective digestion of mouse chromosomes with restriction endonucleases. II. X-ray microanalysis of HaeIII-treated chromosomes.
Cytogenetics and cell genetics 1991;56(2):82-6.
1991: Carmen López-Fernández; Jaime Gosálvez; L Ferrucci; R Mezzannotte
Restriction endonucleases in the study of eukaryotic chromosomes.
Genetica 1991;83(3):257-74.
1991: J L Bella; Jaime Gosálvez
C-banding with specific fluorescent DNA-ligands: a new approach to constitutive heterochromatin heterogeneity.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 1991;1(1):44-52.
1990: Jaime Gosálvez; A T Sumner; Carmen López-Fernández; Rossano Rossino; Vicente Goyanes; R Mezzanotte
Electron microscopy and biochemical analysis of mouse metaphase chromosomes after digestion with restriction endonucleases.
Chromosoma 1990;99(1):36-43.
1990: Jaime Gosálvez; Carmen López-Fernández; A Campos; M Rodriguez; E Rodriguez; Vicente Goyanes
Differential action of restriction endonucleases on chromosomes prepared for light and electron microscopy.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1990;33(1):155-7.
1990: P Del Castillo; A R Llorente; A Gómez; Jaime Gosálvez; Vicente Goyanes; Juan C Stockert
New fluorescence reactions in DNA cytochemistry. 2. Microscopic and spectroscopic studies on fluorescent aluminum complexes.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1990;12(1):11-20.
1990: C García de la Vega; J M Martínez Zapater; Carmen López-Fernández; Vicente Goyanes; R Mezzanotte; Jaime Gosálvez
In situ random primer extension of metaphase chromosomes.
Cytogenetics and cell genetics 1990;53(4):211-2.
1990: C García de la Vega; Carmen López-Fernández; P Esponda; A Campos; Vicente Goyanes; Jaime Gosálvez
Scaffold-like structures in mouse chromosomes revealed by restriction endonuclease digestion and electron microscopy.
Biology of the cell / under the auspices of the European Cell Biology Organization 1990;68(2):101-4.
1990: J de la Torre; Vicente Goyanes; Jaime Gosálvez
Discontinuous undercondensation of centromeric heterochromatin in mouse chromosomes: evidence in Hoechst 33258-treated cells.
Cytogenetics and cell genetics 1990;54(1-2):55-7.
1989: Jaime Gosálvez; Carmen López-Fernández; Vicente Goyanes
Detection of cryptic bands by AluI in eukaryotic chromosomes.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;32(4):672-5.
1988: Jaime Gosálvez; Vicente Goyanes
Selective digestion of mouse chromosomes with restriction endonucleases. I. Scaffold-like structures and bands by electron microscopy.
Cytogenetics and cell genetics 1988;48(4):198-200.
1987: Jaime Gosálvez; J L Bella; Carmen López-Fernández; R Mezzanotte
Correlation between constitutive heterochromatin and restriction enzyme resistant chromatin in Arcyptera tornosi (Orthoptera).
Heredity 1987;59 ( Pt 2)():173-80.
1987: J de la Torre; E Torroja; Jaime Gosálvez; Carmen López-Fernández
A model for quantifying genetic recombination in chromosome polymorphisms due to supernumerary heterochromatic segments.
Heredity 1987;58 ( Pt 3)():345-9.
1986: Jaime Gosálvez; Carmen López-Fernández; J de la Torre; José A Suja; Julio S Rufas
A method for visualizing the acrosome by light microscopy.
Stain technology 1986;61(4):227-30.
1985: P Herrero; Jaime Gosálvez
Presence of intrachromatidic bands in mitotic chromosomes of Triturus marmoratus (Amphibia: Caudata).
Experientia 1985;41(5):683-4.