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Fumi Goshima

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Ushijima Yoko; Goshima Fumi; Kimura Hiroshi; Nishiyama Yukihiro
Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions.
Nawa Akihiro; Luo ChenHong; Zhang Lumin; Ushjima Yoko; Ishida Daisuke; Kamakura Maki; Fujimoto Yasushi; Goshima Fumi; Kikkawa Fumitaka; Nishiyama Yukihiro
Non-engineered, naturally oncolytic herpes simplex virus HSV1 HF-10: applications for cancer gene therapy.
Ushijima Yoko; Koshizuka Tetsuo; Goshima Fumi; Kimura Hiroshi; Nishiyama Yukihiro
Herpes simplex virus type 2 UL56 interacts with the ubiquitin ligase Nedd4 and increases its ubiquitination.

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2009: Ushijima Yoko; Goshima Fumi; Kimura Hiroshi; Nishiyama Yukihiro
Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions.
Virology journal 2009;6():168.
2008: Nawa Akihiro; Luo ChenHong; Zhang Lumin; Ushjima Yoko; Ishida Daisuke; Kamakura Maki; Fujimoto Yasushi; Goshima Fumi; Kikkawa Fumitaka; Nishiyama Yukihiro
Non-engineered, naturally oncolytic herpes simplex virus HSV1 HF-10: applications for cancer gene therapy.
Current gene therapy 2008;8(3):208-21.
2008: Ushijima Yoko; Koshizuka Tetsuo; Goshima Fumi; Kimura Hiroshi; Nishiyama Yukihiro
Herpes simplex virus type 2 UL56 interacts with the ubiquitin ligase Nedd4 and increases its ubiquitination.
Journal of virology 2008;82(11):5220-33.
2008: Kamakura Maki; Nawa Akihiro; Ushijima Yoko; Goshima Fumi; Kawaguchi Yasushi; Kikkawa Fumitaka; Nishiyama Yukihiro
Microarray analysis of transcriptional responses to infection by herpes simplex virus types 1 and 2 and their US3-deficient mutants.
Microbes and infection / Institut Pasteur 2008;10(4):405-13.
2007: Kohno S-I; Luo C; Nawa A; Fujimoto Y; Watanabe D; Goshima F; Tsurumi T; Nishiyama Y
Oncolytic virotherapy with an HSV amplicon vector expressing granulocyte-macrophage colony-stimulating factor using the replication-competent HSV type 1 mutant HF10 as a helper virus.
Cancer gene therapy 2007;14(11):918-26.
2007: Luo Chenhong; Mori Isamu; Goshima Fumi; Ushijima Yoko; Nawa Akihiro; Kimura Hiroshi; Nishiyama Yukihiro
Replication-competent, oncolytic herpes simplex virus type 1 mutants induce a bystander effect following ganciclovir treatment.
The journal of gene medicine 2007;9(10):875-83.
2007: Nishiyama Yukihiro; Goshima Fumi
[Oncolytic virotherapy using replication-competent herpes simplex viruses]
Uirusu. Journal of virology 2007;57(1):57-65.
2007: Shimoyama S; Goshima F; Teshigahara O; Kasuya H; Kodera Y; Nakao A; Nishiyama Y
Enhanced efficacy of herpes simplex virus mutant HF10 combined with paclitaxel in peritoneal cancer dissemination models.
Hepato-gastroenterology 2007;54(76):1038-42.
2007: Kasuya H; Nishiyama Y; Nomoto S; Goshima F; Takeda S; Watanabe I; Nomura N; Shikano T; Fujii T; Kanazumi N; Nakao A
Suitability of a US3-inactivated HSV mutant (L1BR1) as an oncolytic virus for pancreatic cancer therapy.
Cancer gene therapy 2007;14(6):533-42.
2007: Luo Chenhong; Nawa Akihiro; Yamauchi Youhei; Kohno Shinichi; Ushijima Youko; Goshima Fumi; Kikkawa Fumitaka; Nishiyama Yukihiro
Intercellular trafficking and cytotoxicity of recombinant HSV-1 thymidine kinase fused with HSV-2 US11 RXP repeat peptide.
Virus genes 2007;34(3):263-72.
2007: Nakao A; Takeda S; Shimoyama S; Kasuya H; Kimata H; Teshigahara O; Sawaki M; Kikumori T; Kodera Y; Nagasaka T; Goshima F; Nishiyama Y; Imai T
Clinical experiment of mutant herpes simplex virus HF10 therapy for cancer.
Current cancer drug targets 2007;7(2):169-74.
2007: Ushijima Yoko; Luo Chenhong; Goshima Fumi; Yamauchi Yohei; Kimura Hiroshi; Nishiyama Yukihiro
Determination and analysis of the DNA sequence of highly attenuated herpes simplex virus type 1 mutant HF10, a potential oncolytic virus.
Microbes and infection / Institut Pasteur 2007;9(2):142-9.
2006: Fujimoto Yasushi; Mizuno Terukazu; Sugiura Saiko; Goshima Fumi; Kohno Shin-Ichi; Nakashima Tsutomu; Nishiyama Yukihiro
Intratumoral injection of herpes simplex virus HF10 in recurrent head and neck squamous cell carcinoma.
Acta oto-laryngologica 2006;126(10):1115-7.
2006: Kimata Hideto; Imai Tsuneo; Kikumori Toyone; Teshigahara Osamu; Nagasaka Tetsuro; Goshima Fumi; Nishiyama Yukihiro; Nakao Akimasa
Pilot study of oncolytic viral therapy using mutant herpes simplex virus (HF10) against recurrent metastatic breast cancer.
Annals of surgical oncology 2006;13(8):1078-84.
2006: Mori Isamu; Goshima Fumi; Watanabe Daisuke; Ito Hiroyasu; Koide Naoki; Yoshida Tomoaki; Liu Beixing; Kimura Yoshinobu; Yokochi Takashi; Nishiyama Yukihiro
Herpes simplex virus US3 protein kinase regulates virus-induced apoptosis in olfactory and vomeronasal chemosensory neurons in vivo.
Microbes and infection / Institut Pasteur 2006;8(7):1806-12.
2006: Koshizuka Tetsuo; Kawaguchi Yasushi; Goshima Fumi; Mori Isamu; Nishiyama Yukihiro
Association of two membrane proteins encoded by herpes simplex virus type 2, UL11 and UL56.
Virus genes 2006;32(2):153-63.
2005: Mori Isamu; Liu Beixing; Goshima Fumi; Ito Hiroyasu; Koide Naoki; Yoshida Tomoaki; Yokochi Takashi; Kimura Yoshinobu; Nishiyama Yukihiro
HF10, an attenuated herpes simplex virus (HSV) type 1 clone, lacks neuroinvasiveness and protects mice against lethal challenge with HSV types 1 and 2.
Microbes and infection / Institut Pasteur 2005;7(15):1492-500.
2005: Kohno Shin-ichi; Luo Chenhong; Goshima Fumi; Nishiyama Yukihiro; Sata Tetsutaro; Ono Yoshinari
Herpes simplex virus type 1 mutant HF10 oncolytic viral therapy for bladder cancer.
Urology 2005;66(5):1116-21.
2005: Mori Isamu; Goshima Fumi; Mizuno Terukazu; Imai Yoshinori; Kohsaka Shinichi; Ito Hiroyasu; Koide Naoki; Yoshida Tomoaki; Yokochi Takashi; Kimura Yoshinobu; Nishiyama Yukihiro
Axonal injury in experimental herpes simplex encephalitis.
Brain research 2005;1057(1-2):186-90.
2005: Matsuzaki Akio; Yamauchi Yohei; Kato Akihisa; Goshima Fumi; Kawaguchi Yasushi; Yoshikawa Tetsushi; Nishiyama Yukihiro
US3 protein kinase of herpes simplex virus type 2 is required for the stability of the UL46-encoded tegument protein and its association with virus particles.
The Journal of general virology 2005;86(Pt 7):1979-85.
2005: Mori Isamu; Koshizuka Tetsuo; Goshima Fumi; Ito Hiroyasu; Koide Naoki; Yoshida Tomoaki; Yokochi Takashi; Kimura Yoshinobu; Nishiyama Yukihiro
Intercellular trafficking activity of herpes simplex virus US11 gene product in the mouse brain.
Brain research. Molecular brain research 2005;136(1-2):158-63.
2005: Mori Isamu; Goshima Fumi; Ito Hiroyasu; Koide Naoki; Yoshida Tomoaki; Yokochi Takashi; Kimura Yoshinobu; Nishiyama Yukihiro
The vomeronasal chemosensory system as a route of neuroinvasion by herpes simplex virus.
Virology 2005;334(1):51-8.
2004: Nakao A; Kimata H; Imai T; Kikumori T; Teshigahara O; Nagasaka T; Goshima F; Nishiyama Y
Intratumoral injection of herpes simplex virus HF10 in recurrent breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(6):988-9.
2004: Sugiura Saiko; Goshima Fumi; Takakuwa Hiroki; Sata Tetsutaro; Nakashima Tsutomu; Nishiyama Yukihiro
Treatment of solid sarcomas in immunocompetent mice with novel, oncolytic herpes simplex viruses.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004;130(4):470-8.
2004: Teshigahara Osamu; Goshima Fumi; Takao Kazumasa; Kohno Shin-ichi; Kimata Hideto; Nakao Akimasa; Nishiyama Yukihiro
Oncolytic viral therapy for breast cancer with herpes simplex virus type 1 mutant HF 10.
Journal of surgical oncology 2004;85(1):42-7.
2003: Mori Isamu; Goshima Fumi; Koshizuka Tetsuo; Imai Yoshinori; Kohsaka Shinichi; Koide Naoki; Sugiyama Tsuyoshi; Yoshida Tomoaki; Yokochi Takashi; Kimura Yoshinobu; Nishiyama Yukihiro
Iba1-expressing microglia respond to herpes simplex virus infection in the mouse trigeminal ganglion.
Brain research. Molecular brain research 2003;120(1):52-6.
2003: Mori Isamu; Goshima Fumi; Koshizuka Tetsuo; Koide Naoki; Sugiyama Tsuyoshi; Yoshida Tomoaki; Yokochi Takashi; Kimura Yoshinobu; Nishiyama Yukihiro
The US3 protein kinase of herpes simplex virus attenuates the activation of the c-Jun N-terminal protein kinase signal transduction pathway in infected piriform cortex neurons of C57BL/6 mice.
Neuroscience letters 2003;351(3):201-5.
2003: Nawa Akihiro; Nozawa Naoki; Goshima Fumi; Nagasaka Tetsuo; Kikkawa Fumitaka; Niwa Yoshimitsu; Nakanishi Toru; Kuzuya Kazuo; Nishiyama Yukihiro
Oncolytic viral therapy for human ovarian cancer using a novel replication-competent herpes simplex virus type I mutant in a mouse model.
Gynecologic oncology 2003;91(1):81-8.
2003: Mori Isamu; Goshima Fumi; Koshizuka Tetsuro; Koide Naoki; Sugiyama Tsuyoshi; Yoshida Tomoaki; Yokochi Takashi; Nishiyama Yukihiro; Kimura Yoshinobu
Differential activation of the c-Jun N-terminal kinase/stress-activated protein kinase and p38 mitogen-activated protein kinase signal transduction pathways in the mouse brain upon infection with neurovirulent influenza A virus.
The Journal of general virology 2003;84(Pt 9):2401-8.
2003: Yoshikawa Tetsushi; Goshima Fumi; Akimoto Shiho; Ozaki Takao; Iwasaki Takuya; Kurata Takeshi; Asano Yoshizo; Nishiyama Yukihiro
Human herpesvirus 6 infection of human epidermal cell line: pathogenesis of skin manifestations.
Journal of medical virology 2003;71(1):62-8.
2003: Kimata Hideto; Takakuwa Hiroki; Goshima Fumi; Teshigahara Osamu; Nakao Akimasa; Kurata Takeshi; Sata Tetsutaro; Nishiyama Yukihiro
Effective treatment of disseminated peritoneal colon cancer with new replication-competent herpes simplex viruses.
Hepato-gastroenterology 2003;50(52):961-6.
2003: Takakuwa H; Goshima F; Nozawa N; Yoshikawa T; Kimata H; Nakao A; Nawa A; Kurata T; Sata T; Nishiyama Y
Oncolytic viral therapy using a spontaneously generated herpes simplex virus type 1 variant for disseminated peritoneal tumor in immunocompetent mice.
Archives of virology 2003;148(4):813-25.
2003: Yamauchi Yohei; Daikoku Tohru; Goshima Fumi; Nishiyama Yukihiro
Herpes simplex virus UL14 protein blocks apoptosis.
Microbiology and immunology 2003;47(9):685-9.
2002: Yamauchi Yohei; Goshima Fumi; Yoshikawa Tetsushi; Nozawa Naoki; Koshizuka Tetsuo; Nishiyama Yukihiro
Intercellular trafficking of herpes simplex virus type 2 UL14 deletion mutant proteins.
Biochemical and biophysical research communications 2002;298(3):357-63.
2002: Murata Takayuki; Goshima Fumi; Takakuwa Hiroki; Nishiyama Yukihiro
Excretion of herpes simplex virus type 2 glycoprotein D into the culture medium.
The Journal of general virology 2002;83(Pt 11):2791-5.
2002: Koshizuka Tetsuo; Goshima Fumi; Takakuwa Hiroki; Nozawa Naoki; Daikoku Tohru; Koiwai Osamu; Nishiyama Yukihiro
Identification and characterization of the UL56 gene product of herpes simplex virus type 2.
Journal of virology 2002;76(13):6718-28.
2002: Nozawa Naoki; Daikoku Tohru; Yamauchi Yohei; Takakuwa Hiroki; Goshima Fumi; Yoshikawa Tetsushi; Nishiyama Yukihiro
Identification and characterization of the UL7 gene product of herpes simplex virus type 2.
Virus genes 2002;24(3):257-66.
2002: Murata Takayuki; Goshima Fumi; Yamauchi Yohei; Koshizuka Tetsuo; Takakuwa Hiroki; Nishiyama Yukihiro
Herpes simplex virus type 2 US3 blocks apoptosis induced by sorbitol treatment.
Microbes and infection / Institut Pasteur 2002;4(7):707-12.
2002: Yamauchi Yohei; Wada Kaoru; Goshima Fumi; Daikoku Tohru; Ohtsuka Kenzo; Nishiyama Yukihiro
Herpes simplex virus type 2 UL14 gene product has heat shock protein (HSP)-like functions.
Journal of cell science 2002;115(Pt 12):2517-27.
2002: Yoshikawa Tetsushi; Asano Yoshizo; Akimoto Shiho; Ozaki Takao; Iwasaki Takuya; Kurata Takeshi; Goshima Fumi; Nishiyama Yukihiro
Latent infection of human herpesvirus 6 in astrocytoma cell line and alteration of cytokine synthesis.
Journal of medical virology 2002;66(4):497-505.
2002: Murata Takayuki; Goshima Fumi; Nishizawa Yuji; Daikoku Tohru; Takakuwa Hiroki; Ohtsuka Kenzo; Yoshikawa Tetsushi; Nishiyama Yukihiro
Phosphorylation of cytokeratin 17 by herpes simplex virus type 2 US3 protein kinase.
Microbiology and immunology 2002;46(10):707-19.
2001: Takakuwa H; Goshima F; Koshizuka T; Murata T; Daikoku T; Nishiyama Y
Herpes simplex virus encodes a virion-associated protein which promotes long cellular processes in over-expressing cells.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(11):955-66.
2001: Koshizuka T; Takakuwa H; Goshima F; Murata T; Nishiyama Y
The US11 gene product of herpes simplex virus has intercellular trafficking activity.
Biochemical and biophysical research communications 2001;288(3):597-602.
2001: Hong-Yan Z; Murata T; Goshima F; Takakuwa H; Koshizuka T; Yamauchi Y; Nishiyama Y
Identification and characterization of the UL24 gene product of herpes simplex virus type 2.
Virus genes 2001;22(3):321-7.
2001: Yamauchi Y; Shiba C; Goshima F; Nawa A; Murata T; Nishiyama Y
Herpes simplex virus type 2 UL34 protein requires UL31 protein for its relocation to the internal nuclear membrane in transfected cells.
The Journal of general virology 2001;82(Pt 6):1423-8.
2001: Yamauchi Y; Wada K; Goshima F; Takakuwa H; Daikoku T; Yamada M; Nishiyama Y
The UL14 protein of herpes simplex virus type 2 translocates the minor capsid protein VP26 and the DNA cleavage and packaging UL33 protein into the nucleus of coexpressing cells.
The Journal of general virology 2001;82(Pt 2):321-30.
2001: Murata T; Goshima F; Koshizuka T; Takakuwa H; Nishiyama Y
A single amino acid substitution in the ICP27 protein of herpes simplex virus type 1 is responsible for its resistance to leptomycin B.
Journal of virology 2001;75(2):1039-43.
2001: Goshima F; Watanabe D; Suzuki H; Takakuwa H; Yamada H; Nishiyama Y
The US2 gene product of herpes simplex virus type 2 interacts with cytokeratin 18.
Archives of virology 2001;146(11):2201-9.
2000: Murata T; Goshima F; Daikoku T; Takakuwa H; Nishiyama Y
Expression of herpes simplex virus type 2 US3 affects the Cdc42/Rac pathway and attenuates c-Jun N-terminal kinase activation.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(12):1017-27.
2000: Asano S; Honda T; Goshima F; Nishiyama Y; Sugiura Y
US3 protein kinase of herpes simplex virus protects primary afferent neurons from virus-induced apoptosis in ICR mice.
Neuroscience letters 2000;294(2):105-8.
2000: Tsunobuchi H; Nishimura H; Goshima F; Daikoku T; Nishiyama Y; Yoshikai Y
Memory-type CD8+ T cells protect IL-2 receptor alpha-deficient mice from systemic infection with herpes simplex virus type 2.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4552-60.
2000: Watanabe D; Ushijima Y; Goshima F; Takakuwa H; Tomita Y; Nishiyama Y
Identification of nuclear export signal in UL37 protein of herpes simplex virus type 2.
Biochemical and biophysical research communications 2000;276(3):1248-54.
2000: Shiba C; Daikoku T; Goshima F; Takakuwa H; Yamauchi Y; Koiwai O; Nishiyama Y
The UL34 gene product of herpes simplex virus type 2 is a tail-anchored type II membrane protein that is significant for virus envelopment.
The Journal of general virology 2000;81(Pt 10):2397-405.
2000: Tsunobuchi H; Nishimura H; Goshima F; Daikoku T; Suzuki H; Nakashima I; Nishiyama Y; Yoshikai Y
A protective role of interleukin-15 in a mouse model for systemic infection with herpes simplex virus.
Virology 2000;275(1):57-66.
2000: Murata T; Goshima F; Daikoku T; Inagaki-Ohara K; Takakuwa H; Kato K; Nishiyama Y
Mitochondrial distribution and function in herpes simplex virus-infected cells.
The Journal of general virology 2000;81(Pt 2):401-6.
2000: Kato K; Daikoku T; Goshima F; Kume H; Yamaki K; Nishiyama Y
Synthesis, subcellular localization and VP16 interaction of the herpes simplex virus type 2 UL46 gene product.
Archives of virology 2000;145(10):2149-62.
2000: Inagaki-Ohara K; Daikoku T; Goshima F; Nishiyama Y
Impaired induction of protective immunity by highly virulent herpes simplex virus type 2 in a murine model of genital herpes.
Archives of virology 2000;145(10):1989-2002.
2000: Goshima F; Watanabe D; Takakuwa H; Wada K; Daikoku T; Yamada M; Nishiyama Y
Herpes simplex virus UL17 protein is associated with B capsids and colocalizes with ICP35 and VP5 in infected cells.
Archives of virology 2000;145(2):417-26.
1999: Wada K; Goshima F; Takakuwa H; Yamada H; Daikoku T; Nishiyama Y
Identification and characterization of the UL14 gene product of herpes simplex virus type 2.
The Journal of general virology 1999;80 ( Pt 9)():2423-31.
1999: Asano S; Honda T; Goshima F; Watanabe D; Miyake Y; Sugiura Y; Nishiyama Y
US3 protein kinase of herpes simplex virus type 2 plays a role in protecting corneal epithelial cells from apoptosis in infected mice.
The Journal of general virology 1999;80 ( Pt 1)():51-6.
1998: Daikoku T; Ikenoya K; Yamada H; Goshima F; Nishiyama Y
Identification and characterization of the herpes simplex virus type 1 UL51 gene product.
The Journal of general virology 1998;79 ( Pt 12)():3027-31.
1998: Jiang Y M; Yamada H; Goshima F; Daikoku T; Oshima S; Wada K; Nishiyama Y
Characterization of the herpes simplex virus type 2 (HSV-2) US2 gene product and a US2-deficient HSV-2 mutant.
The Journal of general virology 1998;79 ( Pt 11)():2777-84.
1998: Yamada H; Jiang Y M; Oshima S; Wada K; Goshima F; Daikoku T; Nishiyama Y
Characterization of the UL4 gene product of herpes simplex virus type 2.
Archives of virology 1998;143(6):1199-207.
1998: Oshima S; Daikoku T; Shibata S; Yamada H; Goshima F; Nishiyama Y
Characterization of the UL16 gene product of herpes simplex virus type 2.
Archives of virology 1998;143(5):863-80.
1998: Goshima F; Daikoku T; Yamada H; Oshima S; Tsurumi T; Nishiyama Y
Subcellular localization of the US3 protein kinase of herpes simplex virus type 2.
Archives of virology 1998;143(3):613-22.
1997: Daikoku T; Shibata S; Goshima F; Oshima S; Tsurumi T; Yamada H; Yamashita Y; Nishiyama Y
Purification and characterization of the protein kinase encoded by the UL13 gene of herpes simplex virus type 2.
Virology 1997;235(1):82-93.
1991: Yamada Y; Shimokata K; Yamada Y; Yamamoto N; Goshima F; Nishiyama Y
Inhibition of influenza A virus replication by a kanamycin derivative.
Antiviral research 1991;15(3):171-82.
1989: Goshima F Y; Maeno K
Persistent infection of MDCK cells by influenza C virus: initiation and characterization.
The Journal of general virology 1989;70 ( Pt 12)():3481-5.

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