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Yoshio Goshima

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Masumi Iketani; Yuji Kurihara; Masayuki Matsushita; Angus C Nairn; Fumio Nakamura; Yukio Sasaki; Yasufumi Sato; Kumiko Sengoku; Ken Takamatsu; Yoshio Goshima; Akira Iizuka; Masayuki Yamane; Kohtaro Takei
Regulation of neurite outgrowth mediated by localized phosphorylation of protein translational factor eEF2 in growth cones.
Shu Takagawa; Yoshio Goshima; Ken Kumagai; Yoji Nagashima; Fumio Nakamura; Tomoyuki Saito
Decreased Semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis.
Kazuki Orime; Koichiro Sato; Jun Shirakawa; Kazuki Tajima; Kazutaka Aoki; Yoshio Goshima; Hideaki Inoue; Yuzuru Ito; Akinobu Nakamura; Yu Togashi; Yasuo Terauchi
Trefoil factor 2 promotes cell proliferation in pancreatic β-cells through CXCR-4-mediated ERK1/2 phosphorylation.

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2013: Masumi Iketani; Yuji Kurihara; Masayuki Matsushita; Angus C Nairn; Fumio Nakamura; Yukio Sasaki; Yasufumi Sato; Kumiko Sengoku; Ken Takamatsu; Yoshio Goshima; Akira Iizuka; Masayuki Yamane; Kohtaro Takei
Regulation of neurite outgrowth mediated by localized phosphorylation of protein translational factor eEF2 in growth cones.
Developmental neurobiology 2013;73(3):230-46.
2013: Shu Takagawa; Yoshio Goshima; Ken Kumagai; Yoji Nagashima; Fumio Nakamura; Tomoyuki Saito
Decreased Semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis.
BMC musculoskeletal disorders 2013;14():40.
2013: Kazuki Orime; Koichiro Sato; Jun Shirakawa; Kazuki Tajima; Kazutaka Aoki; Yoshio Goshima; Hideaki Inoue; Yuzuru Ito; Akinobu Nakamura; Yu Togashi; Yasuo Terauchi
Trefoil factor 2 promotes cell proliferation in pancreatic β-cells through CXCR-4-mediated ERK1/2 phosphorylation.
Endocrinology 2013;154(1):54-64.
2012: Masakazu Higurashi; Masumi Iketani; Nobutaka Kawahara; Kohtaro Takei; Naoya Yamashita; Reina Aoki; Yoshio Goshima
Localized role of CRMP1 and CRMP2 in neurite outgrowth and growth cone steering.
Developmental neurobiology 2012;72(12):1528-40.
2012: Yoshio Goshima; Yukio Sasaki; Naoya Yamashita; Fumio Nakamura
Class 3 semaphorins as a therapeutic target.
Expert opinion on therapeutic targets 2012;16(9):933-44.
2012: Kenzen Kou; Yoji Nagashima; Fumio Nakamura; Katsuya Seto; Michiko Aihara; Huichin Chen; Yoshio Goshima; Takeshi Kambara; Junko Komori-Yamaguchi; Zenro Ikezawa
Decreased expression of semaphorin-3A, a neurite-collapsing factor, is associated with itch in psoriatic skin.
Acta dermato-venereologica 2012;92(5):521-8.
2012: Tomonobu Hida; Akira Kikuchi; Fumio Nakamura; Yukio Sasaki; Hiroshi Usui; Naoya Yamashita; Yoshio Goshima
GSK3β/axin-1/β-catenin complex is involved in semaphorin3A signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(35):11905-18.
2012: Jun Shirakawa; Kazuki Tajima; Ritsuko Tanami; Yoshio Goshima; Takashi Kadowaki; Naoto Kubota; Kazuki Orime; Yu Togashi; Yasuo Terauchi
Effects of liraglutide on β-cell-specific glucokinase-deficient neonatal mice.
Endocrinology 2012;153(7):3066-75.
2012: Jun Shirakawa; Kazuki Tajima; Yu Togashi; Yoshio Goshima; Kaori Kikuchi; Mari Kimura; Takashi Miyazaki; Kazuki Orime; Koichiro Sato; Yasuo Terauchi
Plasminogen activator inhibitor-1 is associated with renal dysfunction independent of BMI and serum lipid levels in patients with type 2 diabetes.
Diabetes research and clinical practice 2012;97(1):e9-12.
2012: Masayuki Yamane; Naoya Yamashita; Akira Iizuka; Masayuki Shouji; Hiroshi Usui; Hiroshi Yamamoto; Yoshio Goshima
Semaphorin3A facilitates axonal transport through a local calcium signaling and tetrodotoxin-sensitive voltage-gated sodium channels.
Biochemical and biophysical research communications 2012;422(2):333-8.
2012: Ken-ichi Ogura; Taro Asakura; Yoshio Goshima
Localization mechanisms of the axon guidance molecule UNC-6/Netrin and its receptors, UNC-5 and UNC-40, in Caenorhabditis elegans.
Development, growth & differentiation 2012;54(3):390-7.
2012: Naoya Yamashita; Yoshio Goshima
Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status.
Molecular neurobiology 2012;45(2):234-46.
2012: Yusuke Kobayashi; Katsuhiko Kohara; Tetsuro Miki; Nobuko Miyazaki; Hidenori Muraoka; Sanae Saka; Yasuharu Tabara; Kohtaro Takei; Yoshiyuki Toya; Hirotsugu Ueshima; Megumi Fujita; Akira Fujiwara; Yoshio Goshima; Nobuhito Hirawa; Naoaki Ichihara; Yasuhiro Ichikawa; Yoshihiro Ishikawa; Yoshikuni Kita; Hiromichi Wakui; Yuichiro Yamamoto; Gen Yasuda; Keisuke Yatsu; Shin-ichiro Yoshida; Satoshi Umemura
Mice lacking hypertension candidate gene ATP2B1 in vascular smooth muscle cells show significant blood pressure elevation.
Hypertension 2012;59(4):854-60.
2012: Yuji Kurihara; Nobuhisa Mizuki; Fumio Nakamura; Kuniyuki Nishiyama; Yasufumi Sato; Yuko Arie; Yoshio Goshima; Masumi Iketani; Hiromu Ito; Kohtaro Takei
The carboxyl-terminal region of Crtac1B/LOTUS acts as a functional domain in endogenous antagonism to Nogo receptor-1.
Biochemical and biophysical research communications 2012;418(2):390-5.
2012: Naoya Yamashita; Jérôme Honnorat; Papachan Kolattukudy; Katsuhiko Mikoshiba; Fumio Nakamura; Toshio Ohshima; Yoshio Goshima
Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(4):1360-5.
2012: Yoshio Goshima; Tomonobu Hida; Toshiyuki Gotoh
Computational analysis of axonal transport: a novel assessment of neurotoxicity, neuronal development and functions.
International journal of molecular sciences 2012;13(3):3414-30.
2011: Shingo Kato; Noritoshi Kobayashi; Kensuke Kubota; Yoshinobu Kubota; Shin Maeda; Satoshi Morita; Yoji Nagashima; Noboru Nakaigawa; Atsushi Nakajima; Fumio Nakamura; Takeshi Shimamura; Yoshiyasu Shinohara; Masataka Taguri; Seitaro Watanabe; Masato Yoneda; Itaru Endo; Yoshio Goshima; Masahiko Inamori; Hitoshi Ishiguro; Hitoshi Nakagama
Semaphorin 4D, a lymphocyte semaphorin, enhances tumor cell motility through binding its receptor, plexinB1, in pancreatic cancer.
Cancer science 2011;102(11):2029-37.
2011: Yasufumi Sato; Stephen M Strittmatter; Megumi Yamaguchi; Naoya Yamashita; Takaya Abe; Yuko Arie; Yoshio Goshima; Tatsumi Hirata; Masumi Iketani; Takahiko Kawasaki; Hiroshi Kiyonari; Yuji Kurihara; Fumio Nakamura; Kohtaro Takei
Cartilage acidic protein-1B (LOTUS), an endogenous Nogo receptor antagonist for axon tract formation.
Science (New York, N.Y.) 2011;333(6043):769-73.
2011: Naoya Yamashita; Bedrich Mosinger; Arpita Roy; Mari Miyazaki; Kozue Ugajin; Fumio Nakamura; Yukio Sasaki; Kazuhiko Yamaguchi; Pappachan Kolattukudy; Yoshio Goshima
CRMP5 (collapsin response mediator protein 5) regulates dendritic development and synaptic plasticity in the cerebellar Purkinje cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(5):1773-9.
2011: Haruna Sawaki; Naoya Yamashita; Michiko Aihara; Yoshio Goshima; Junko Komori-Yamaguchi; Yoji Nagashima; Fumio Nakamura; Masatoshi Nakazawa; Zenro Ikezawa
Intranasal administration of semaphorin-3A alleviates sneezing and nasal rubbing in a murine model of allergic rhinitis.
Journal of pharmacological sciences 2011;117(1):34-44.
2011: Michihiko Fujii; Kazuki Shikatani; Ken-Ichi Ogura; Yoshio Goshima; Dai Ayusawa
Mutation in a mitochondrial ribosomal protein causes increased sensitivity to oxygen with decreased longevity in the nematode Caenorhabditis elegans.
Genes to cells : devoted to molecular & cellular mechanisms 2011;16(1):69-79.
2011: Michiko Hayashi; Yoshinori Kamiya; Hideki Itoh; Tomoko Higashi; Tomoyuki Miyazaki; Kengo Funakoshi; Naoya Yamashita; Yoshio Goshima; Tomio Andoh; Yoshitsugu Yamada; Takahisa Goto
Intrathecally administered Sema3A protein attenuates neuropathic pain behavior in rats with chronic constriction injury of the sciatic nerve.
Neuroscience research 2011;69(1):17-24.
2010: Taro Asakura; Naoko Waga; Ken-Ichi Ogura; Yoshio Goshima
Genes required for cellular UNC-6/netrin localization in Caenorhabditis elegans.
Genetics 2010;185(2):573-85.
2010: Ken-ichi Ogura; Takako Okada; Shohei Mitani; Keiko Gengyo-Ando; David L Baillie; Yuji Kohara; Yoshio Goshima
Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans.
Development (Cambridge, England) 2010;137(10):1657-67.
2010: Yoshio Goshima; Hiroshi Usui; Takahito Shiozawa; Tomonobu Hida; Satoshi Kuraoka; Sayumi Takeshita; Naoya Yamashita; Yasushi Ichikawa; Yoshinori Kamiya; Takahisa Gotoh; Toshiyuki Gotoh
Computational analysis of the effects of antineoplastic agents on axonal transport.
Journal of pharmacological sciences 2010;114(2):168-79.
2009: Fumio Nakamura; Kozue Ugajin; Naoya Yamashita; Takako Okada; Yutaka Uchida; Masahiko Taniguchi; Toshio Ohshima; Yoshio Goshima
Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.
The Journal of comparative neurology 2009;516(5):360-75.
2009: Yutaka Uchida; Toshio Ohshima; Naoya Yamashita; Miyuki Ogawara; Yukio Sasaki; Fumio Nakamura; Yoshio Goshima
Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.
The Journal of biological chemistry 2009;284(40):27393-401.
2009: Taro Fuchikawa; Fumio Nakamura; Nana Fukuda; Kohtaro Takei; Yoshio Goshima
Protein tyrosine phosphatase SHP2 is involved in Semaphorin 4D-induced axon repulsion.
Biochemical and biophysical research communications 2009;385(1):6-10.
2009: M Iketani; C Imaizumi; Fumio Nakamura; A Jeromin; Katsuhiko Mikoshiba; Yoshio Goshima; Kohtaro Takei
Regulation of neurite outgrowth mediated by neuronal calcium sensor-1 and inositol 1,4,5-trisphosphate receptor in nerve growth cones.
Neuroscience 2009;161(3):743-52.
2009: Naoko Matsushita; Yoshimi Misu; Yoshio Goshima
In vivo antagonism of the behavioral responses to L-3-,4-dihydroxyphenylalanine by L-3-,4-dihydroxyphenylalanine cyclohexyl ester in conscious rats.
European journal of pharmacology 2009;605(1-3):109-13.
2009: Yuko Arie; Masumi Iketani; Ken Takamatsu; Katsuhiko Mikoshiba; Yoshio Goshima; Kohtaro Takei
Developmental changes in the regulation of calcium-dependent neurite outgrowth.
Biochemical and biophysical research communications 2009;379(1):11-5.
2008: Junko Yamaguchi; Fumio Nakamura; Michiko Aihara; Naoya Yamashita; Hiroshi Usui; Tomonobu Hida; Kohtaro Takei; Yoji Nagashima; Zenro Ikezawa; Yoshio Goshima
Semaphorin3A alleviates skin lesions and scratching behavior in NC/Nga mice, an atopic dermatitis model.
The Journal of investigative dermatology 2008;128(12):2842-9.
2008: Y Murota; M Fujii; Y Sugiyama; Toshiya Funabashi; T Yagami; Tatsuya Takahashi; Yoshio Goshima
DOPA cyclohexyl ester, a DOPA antagonist, blocks the depressor responses elicited by microinjections of nicotine into the nucleus tractus solitarii of rats.
Neuroscience letters 2008;442(2):114-7.
2008: Naomi Araki; Masanari Umemura; Yohei Miyagi; Machiko Yabana; Yuko Miki; Koichi Tamura; Kazuaki Uchino; Reina Aoki; Yoshio Goshima; Satoshi Umemura; Tomoaki Ishigami
Expression, transcription, and possible antagonistic interaction of the human Nedd4L gene variant: implications for essential hypertension.
Hypertension 2008;51(3):773-7.
2007: Naoya Yamashita; Asa Morita; Yutaka Uchida; Fumio Nakamura; Hiroshi Usui; Toshio Ohshima; Masahiko Taniguchi; Jérôme Honnorat; Nicole Thomasset; Kohtaro Takei; Takuya Takahashi; Pappachan Kolattukudy; Yoshio Goshima
Regulation of spine development by semaphorin3A through cyclin-dependent kinase 5 phosphorylation of collapsin response mediator protein 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(46):12546-54.
2007: Taro Asakura; Ken-ichi Ogura; Yoshio Goshima
UNC-6 expression by the vulval precursor cells of Caenorhabditis elegans is required for the complex axon guidance of the HSN neurons.
Developmental biology 2007;304(2):800-10.
2007: Akira Iizuka; Kumiko Sengoku; Masumi Iketani; Fumio Nakamura; Yasufumi Sato; Masayuki Matsushita; Angus Nairn; Ken Takamatsu; Yoshio Goshima; Kohtaro Takei
Calcium-induced synergistic inhibition of a translational factor eEF2 in nerve growth cones.
Biochemical and biophysical research communications 2007;353(2):244-50.
2006: Naoya Yamashita; Yutaka Uchida; Toshio Ohshima; Syu-ichi Hirai; Fumio Nakamura; Masahiko Taniguchi; Katsuhiko Mikoshiba; Jérôme Honnorat; Pappachan Kolattukudy; Nicole Thomasset; Kohtaro Takei; Takuya Takahashi; Yoshio Goshima
Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(51):13357-62.
2006: Emmanuelle Charrier; Bedrich Mosinger; Claire Meissirel; Michèle Aguera; Véronique Rogemond; Sophie Reibel; Paul Salin; Naura Chounlamountri; Valérie Perrot; Marie-Françoise Belin; Yoshio Goshima; Jérôme Honnorat; Nicole Thomasset; Pappachan Kolattukudy
Transient alterations in granule cell proliferation, apoptosis and migration in postnatal developing cerebellum of CRMP1-/- mice.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(12):1337-52.
2006: Jun-ichi Izawa; Kaori Yamanashi; Taro Asakura; Yoshimi Misu; Yoshio Goshima
Differential effects of methamphetamine and cocaine on behavior and extracellular levels of dopamine and 3,4-dihydroxyphenylalanine in the nucleus accumbens of conscious rats.
European journal of pharmacology 2006;549(1-3):84-90.
2006: Ken-Ichi Ogura; Yoshio Goshima
The autophagy-related kinase UNC-51 and its binding partner UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans.
Development (Cambridge, England) 2006;133(17):3441-50.
2006: Oumi Nakajima; Fumio Nakamura; Naoya Yamashita; Yusuke Tomita; Fumikazu Suto; Takako Okada; Akihiro Iwamatsu; Eisaku Kondo; Hajime Fujisawa; Kohtaro Takei; Yoshio Goshima
FKBP133: a novel mouse FK506-binding protein homolog alters growth cone morphology.
Biochemical and biophysical research communications 2006;346(1):140-9.
2006: Yoshio Goshima
[Molecular mechanism of axon guidance].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 2006;26(3):135-40.
2006: M Shimamura; M Shimizu; T Yagami; T Funabashi; F Kimura; Y Kuroiwa; Yoshimi Misu; Yoshio Goshima
L-3,4-dihydroxyphenylalanine-induced c-Fos expression in the CNS under inhibition of central aromatic L-amino acid decarboxylase.
Neuropharmacology 2006;50(8):909-16.
2006: Asa Morita; Naoya Yamashita; Yukio Sasaki; Yutaka Uchida; Oumi Nakajima; Fumio Nakamura; Takeshi Yagi; Masahiko Taniguchi; Hiroshi Usui; Ritsuko Katoh-Semba; Kohtaro Takei; Yoshio Goshima
Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(11):2971-80.
2005: Yutaka Uchida; Yoshio Goshima
[Molecular mechanism of axon guidance mediated by phosphorylation of CRMP2].
Seikagaku. The Journal of Japanese Biochemical Society 2005;77(11):1424-7.
2005: Nariko Arimura; Céline Ménager; Yoji Kawano; Takeshi Yoshimura; Saeko Kawabata; Atsushi Hattori; Yuko Fukata; Mutsuki Amano; Yoshio Goshima; Masaki Inagaki; Nobuhiro Morone; Jiro Usukura; Kozo Kaibuchi
Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones.
Molecular and cellular biology 2005;25(22):9973-84.
2005: Yutaka Uchida; Toshio Ohshima; Yukio Sasaki; Hiromi Suzuki; Shigeki Yanai; Naoya Yamashita; Fumio Nakamura; Kohtaro Takei; Yasuo Ihara; Katsuhiko Mikoshiba; Pappachan Kolattukudy; Jérôme Honnorat; Yoshio Goshima
Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(2):165-79.
2004: Ryuji Fukumori; Yusuke Nishigori; Yoshio Goshima; Takao Kubo
Contribution of the medial amygdaloid nucleus to the development of hypertension in spontaneously hypertensive rats.
Neuroscience letters 2004;365(2):128-31.
2004: Chanxia Li; Yukio Sasaki; Kohtaro Takei; Hiroshi Yamamoto; Masayuki Shouji; Yoshinobu Sugiyama; Tadashi Kawakami; Fumio Nakamura; Takeshi Yagi; Toshio Ohshima; Yoshio Goshima
Correlation between semaphorin3A-induced facilitation of axonal transport and local activation of a translation initiation factor eukaryotic translation initiation factor 4E.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(27):6161-70.
2004: Takao Kubo; Hideaki Okatani; Yusuke Nishigori; Yukihiko Hagiwara; Ryuji Fukumori; Yoshio Goshima
Involvement of the medial amygdaloid nucleus in restraint stress-induced pressor responses in rats.
Neuroscience letters 2004;354(1):84-6.
2003: Qi Cheng; Yukio Sasaki; Masayuki Shoji; Yoshinobu Sugiyama; Hideaki Tanaka; Takashi Nakayama; Nobuhisa Mizuki; Fumio Nakamura; Kohtaro Takei; Yoshio Goshima
Cdk5/p35 and Rho-kinase mediate ephrin-A5-induced signaling in retinal ganglion cells.
Molecular and cellular neurosciences 2003;24(3):632-45.
2003: Tomohiro Kanaya; Hideaki Okatani; Yukihiko Hagiwara; Ryuji Fukumori; Yoshio Goshima; Takao Kubo
Projections from the caudal part to the rostral part of the lateral septal area mediate blood pressure increase.
Brain research bulletin 2003;61(5):505-10.
2003: Tamio Iwamoto; Satoshi Okumura; Kousaku Iwatsubo; Jun-ichi Kawabe; Koji Ohtsu; Ikuko Sakai; Yoko Hashimoto; Aki Izumitani; Kazunori Sango; Kyoko Ajiki; Yoshiyuki Toya; Satoshi Umemura; Yoshio Goshima; Nobutaka Arai; Stephen F Vatner; Yoshihiro Ishikawa
Motor dysfunction in type 5 adenylyl cyclase-null mice.
The Journal of biological chemistry 2003;278(19):16936-40.
2003: Mizuki Hashimoto; Takeaki Miyamae; Isao Yamamoto; Yoshio Goshima
DOPA cyclohexyl ester potently inhibits aglycemia-induced release of glutamate in rat striatal slices.
Neuroscience research 2003;45(3):335-44.
2003: Fumikazu Suto; Yasunori Murakami; Fumio Nakamura; Yoshio Goshima; Hajime Fujisawa
Identification and characterization of a novel mouse plexin, plexin-A4.
Mechanisms of development 2003;120(3):385-96.
2003: Yoshimi Misu; Kunio Kitahama; Yoshio Goshima
L-3,4-Dihydroxyphenylalanine as a neurotransmitter candidate in the central nervous system.
Pharmacology & therapeutics 2003;97(2):117-37.
2003: Takao Kubo; Hideaki Okatani; Tomohiro Kanaya; Yukihiko Hagiwara; Ryuji Fukumori; Yoshio Goshima
Cholinergic mechanism in the lateral septal area is involved in the stress-induced blood pressure increase in rats.
Brain research bulletin 2003;59(5):359-64.
2002: Yoshimi Misu; Nobuya Furukawa; Nobutaka Arai; Takeaki Miyamae; Yoshio Goshima; Kiyohide Fujita
DOPA causes glutamate release and delayed neuron death by brain ischemia in rats.
Neurotoxicology and teratology 2002;24(5):629-38.
2002: Yukio Sasaki; Chi Cheng; Yutaka Uchida; Oumi Nakajima; Toshio Ohshima; Takeshi Yagi; Masahiko Taniguchi; Takashi Nakayama; Reiji Kishida; Yoshihisa Kudo; Shigeaki Ohno; Fumio Nakamura; Yoshio Goshima
Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex.
Neuron 2002;35(5):907-20.
2002: Kaori Yamanashi; Takeaki Miyamae; Yukio Sasaki; Masanobu Maeda; Hideyasu Hirano; Yoshimi Misu; Yoshio Goshima
Involvement of nitric oxide production via kynurenic acid-sensitive glutamate receptors in DOPA-induced depressor responses in the nucleus tractus solitarii of anesthetized rats.
Neuroscience research 2002;43(3):231-8.
2002: Yoshimi Misu; Yoshio Goshima; Takeaki Miyamae
Is DOPA a neurotransmitter?
Trends in pharmacological sciences 2002;23(6):262-8.
2002: Yoshio Goshima; Takaaki Ito; Yukio Sasaki; Fumio Nakamura
Semaphorins as signals for cell repulsion and invasion.
The Journal of clinical investigation 2002;109(8):993-8.
2002: Fumio Nakamura; Yoshio Goshima
Structural and functional relation of neuropilins.
Advances in experimental medicine and biology 2002;515():55-69.
2001: Kaori Yamanashi; Takeaki Miyamae; Yoshimi Misu; Yoshio Goshima
Tonic function of nicotinic receptors in stress-induced release of L-DOPA from the nucleus accumbens in freely moving rats.
European journal of pharmacology 2001;424(3):199-202.
2001: Takao Kubo; T Yokoi; Yukihiko Hagiwara; Ryuji Fukumori; Yoshio Goshima; Yoshimi Misu
Characteristics of protective effects of NMDA antagonist and calcium channel antagonist on ischemic calcium accumulation in rat hippocampal CA1 region.
Brain research bulletin 2001;54(4):413-9.
2001: Nobutaka Arai; Nobuya Furukawa; Takeaki Miyamae; Yoshio Goshima; Y Sasaki; E Ohshima; F Suzuki; Kiyohide Fujita; Yoshimi Misu
DOPA cyclohexyl ester, a competitive DOPA antagonist, protects glutamate release and resultant delayed neuron death by transient ischemia in hippocampus CA1 of conscious rats.
Neuroscience letters 2001;299(3):213-6.
2001: Nobuya Furukawa; Nobutaka Arai; Yoshio Goshima; Takeaki Miyamae; E Ohshima; F Suzuki; Kiyohide Fujita; Yoshimi Misu
Endogenously released DOPA is a causal factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in rat striata.
Journal of neurochemistry 2001;76(3):815-24.
2001: Y Sugaya; Y Sasaki; Yoshio Goshima; K Kitahama; T Kusakabe; Takeaki Miyamae; T Kato; Yoshimi Misu
Autoradiographic studies using L-[(14)C]DOPA and L-DOPA reveal regional Na(+)-dependent uptake of the neurotransmitter candidate L-DOPA in the CNS.
Neuroscience 2001;104(1):1-14.
2000: Takaaki Ito; M Kagoshima; Yukio Sasaki; Chanxia Li; Naoko Udaka; T Kitsukawa; Hajime Fujisawa; Masahiko Taniguchi; Takeshi Yagi; H Kitamura; Yoshio Goshima
Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung.
Mechanisms of development 2000;97(1-2):35-45.
2000: Nariko Arimura; Naoyuki Inagaki; K Chihara; Céline Ménager; N Nakamura; Mutsuki Amano; Akihiro Iwamatsu; Yoshio Goshima; Kozo Kaibuchi
Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse.
The Journal of biological chemistry 2000;275(31):23973-80.
2000: H Ishiia; Y Sasaki; Yoshio Goshima; Y Kanai; H Endou; D Ayusawa; H Ono; Takeaki Miyamae; Yoshimi Misu
Involvement of rBAT in Na(+)-dependent and -independent transport of the neurotransmitter candidate L-DOPA in Xenopus laevis oocytes injected with rabbit small intestinal epithelium poly A(+) RNA.
Biochimica et biophysica acta 2000;1466(1-2):61-70.
2000: Yoshio Goshima; Yukio Sasaki; Takashi Nakayama; Takaaki Ito; T Kimura
Functions of semaphorins in axon guidance and neuronal regeneration.
Japanese journal of pharmacology 2000;82(4):273-9.
2000: Nobuya Furukawa; Yoshio Goshima; Takeaki Miyamae; Y Sugiyama; M Shimizu; E Ohshima; F Suzuki; Nobutaka Arai; Kiyohide Fujita; Yoshimi Misu
L-DOPA cyclohexyl ester is a novel potent and relatively stable competitive antagonist against L-DOPA among several L-DOPA ester compounds.
Japanese journal of pharmacology 2000;82(1):40-7.
1999: Takashi Nakayama; Yoshio Goshima; Yoshimi Misu; T Kato
Role of cdk5 and tau phosphorylation in heterotrimeric G protein-mediated retinal growth cone collapse.
Journal of neurobiology 1999;41(3):326-39.
1999: Yoshio Goshima; Nobuya Furukawa; Nobutaka Arai; Takeaki Miyamae; Y Sasaki; M Hashimoto; I Yamamoto; Kiyohide Fujita; A Akaike; Yoshimi Misu
[A DOPA antagonist, DOPA cyclohexyl ester inhibits transient brain ischemia-induced release of glutamate and delayed neuronal cell death in striatal and hippocampal region of in vivo rats].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1999;114 Suppl 1():180P-185P.
1999: Yoshio Goshima; H Hori; Yukio Sasaki; T Yang; M Kagoshima-Maezono; Chanxia Li; Toshifumi Takenaka; Fumio Nakamura; Takuya Takahashi; S M Strittmatter; Yoshimi Misu; Tadashi Kawakami
Growth cone neuropilin-1 mediates collapsin-1/Sema III facilitation of antero- and retrograde axoplasmic transport.
Journal of neurobiology 1999;39(4):579-89.
1999: Yoshio Goshima; K Honjo; Takeaki Miyamae; Yoshimi Misu
The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats.
Neuroscience letters 1999;261(3):155-8.
1999: K Honjo; Yoshio Goshima; Takeaki Miyamae; Yoshimi Misu
GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats.
Neuroscience letters 1999;261(1-2):93-6.
1999: Takeaki Miyamae; Yoshio Goshima; J L Yue; Yoshimi Misu
L-dopaergic components in the caudal ventrolateral medulla in baroreflex neurotransmission.
Neuroscience 1999;92(1):137-49.
1999: M Nishihama; Takeaki Miyamae; Yoshio Goshima; F Okumura; Yoshimi Misu
An L-dopaergic relay from the posterior hypothalamic nucleus to the rostral ventrolateral medulla and its cardiovascular function in anesthetized rats.
Neuroscience 1999;92(1):123-35.
1999: Takeaki Miyamae; Yoshio Goshima; M Shimizu; T Shibata; K Kawashima; E Ohshima; F Suzuki; Yoshimi Misu
Some interactions of L-DOPA and its related compounds with glutamate receptors.
Life sciences 1999;64(12):1045-54.
1998: Yoshimi Misu; Nobuya Furukawa; Nobutaka Arai; Takeaki Miyamae; Yoshio Goshima
[Is endogenously released DOPA itself an upstream factor for increase in glutamate release and delayed neuronal cell death induced by transient ischemia in rats?].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1998;112 Suppl 1():93P-97P.
1998: Yoshimi Misu; Yoshio Goshima; J L Yue; Takeaki Miyamae
Is L-DOPA a neurotransmitter of the primary baroreceptor afferents terminating in the nucleus tractus solitarii of rats?
Advances in pharmacology (San Diego, Calif.) 1998;42():855-8.
1997: Yoshio Goshima
[Regulation of growth cone motility by the repulsive factor collapsin/semaphorin: a role of collapsin response mediator protein (CRMP)].
Seikagaku. The Journal of Japanese Biochemical Society 1997;69(12):1389-92.
1997: Yoshimi Misu; Yoshio Goshima; Takeaki Miyamae; Nobuya Furukawa; Y Sugiyama; Y Okumura; M Shimizu; E Ohshima; F Suzuki
L-DOPA cyclohexyl ester is a novel stable and potent competitive antagonist against L-DOPA, as compared to L-DOPA methyl ester.
Japanese journal of pharmacology 1997;75(3):307-9.
1997: Yoshimi Misu; Yoshio Goshima; Takeaki Miyamae; Nobuya Furukawa; Y Okumura; Y Sugiyama; M Shimizu
[Studies on novel, stable and potent competitive antagonists against L-DOPA].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1997;110 Suppl 1():159P-164P.
1997: Yoshio Goshima; Tadashi Kawakami; H Hori; Yoshinobu Sugiyama; S Takasawa; Y Hashimoto; M Kagoshima-Maezono; Toshifumi Takenaka; Yoshimi Misu; S M Strittmatter
A novel action of collapsin: collapsin-1 increases antero- and retrograde axoplasmic transport independently of growth cone collapse.
Journal of neurobiology 1997;33(3):316-28.
1997: Nobuya Furukawa; Yoshio Goshima; Takeaki Miyamae; M Nishihama; F Okumura; Kiyohide Fujita; Yoshimi Misu
An L-DOPA-like depressor action of L-threo-dihydroxyphenyl-serine in the rat caudal ventrolateral medulla.
Life sciences 1997;61(12):1177-83.
1996: Yoshio Goshima; Takeaki Miyamae; S Nakamura; K Miki; K Kosaka; Yoshimi Misu
Ventral tegmental injection of nicotine induces locomotor activity and L-DOPA release from nucleus accumbens.
European journal of pharmacology 1996;309(3):229-33.
1996: Yoshimi Misu; Yoshio Goshima; H Ueda; H Okamura
Neurobiology of L-DOPAergic systems.
Progress in neurobiology 1996;49(5):415-54.
1996: Takeaki Miyamae; J L Yue; Yoshio Goshima; Yoshimi Misu
Depressor action of L-threo-dihydroxyphenylserine in the rat nucleus tractus solitarii.
European journal of pharmacology 1996;300(1-2):105-8.
1995: Yoshimi Misu; J L Yue; Takeaki Miyamae; Yoshio Goshima
Altered L-DOPA systems for blood pressure regulation in the lower brainstem of spontaneously hypertensive rats.
Hypertension research : official journal of the Japanese Society of Hypertension 1995;18(4):267-77.
1995: Takeaki Miyamae; J L Yue; Y Okumura; Yoshio Goshima; Yoshimi Misu
Loss of tonic neuronal activity to release L-DOPA in the caudal ventrolateral medulla of spontaneously hypertensive rats.
Neuroscience letters 1995;198(1):37-40.
1995: Y Misu; J L Yue; Yoshio Goshima
L-DOPA systems for blood pressure regulation in the lower brainstem.
Neuroscience research 1995;23(2):147-58.
1995: Yoshimi Misu; H Ueda; Yoshio Goshima
Neurotransmitter-like actions of L-DOPA.
Advances in pharmacology (San Diego, Calif.) 1995;32():427-59.
1994: J L Yue; H Okamura; Yoshio Goshima; S Nakamura; M Geffard; Yoshimi Misu
Baroreceptor-aortic nerve-mediated release of endogenous L-3,4-dihydroxyphenylalanine and its tonic depressor function in the nucleus tractus solitarii of rats.
Neuroscience 1994;62(1):145-61.
1994: S Nakamura; J L Yue; Yoshio Goshima; Takeaki Miyamae; H Ueda; Yoshimi Misu
Non-effective dose of exogenously applied L-dopa itself stereoselectively potentiates postsynaptic D2 receptor-mediated locomotor activities of conscious rats.
Neuroscience letters 1994;170(1):22-6.
1993: J L Yue; Yoshio Goshima; Takeaki Miyamae; Yoshimi Misu
Evidence for L-dopa relevant to modulation of sympathetic activity in the rostral ventrolateral medulla of rats.
Brain research 1993;629(2):310-4.
1993: J L Yue; Yoshio Goshima; Yoshimi Misu
Transmitter-like L-3,4-dihydroxyphenylalanine tonically functions to mediate vasodepressor control in the caudal ventrolateral medulla of rats.
Neuroscience letters 1993;159(1-2):103-6.
1993: Yoshio Goshima; K Ohno; S Nakamura; Takeaki Miyamae; Yoshimi Misu; A Akaike
L-dopa induces Ca(2+)-dependent and tetrodotoxin-sensitive release of endogenous glutamate from rat striatal slices.
Brain research 1993;617(1):167-70.
1993: Yoshio Goshima
[Transmitter-like release and pharmacological activities of levodopa].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica 1993;102(1):11-21.
1993: Yoshimi Misu; S Nakamura; Yoshio Goshima; J L Yue; Takeaki Miyamae; T Kubo
Review on the relationship between nicotinic acetylcholine receptors and dopaminergic neurotransmission in the central nervous system--dopa is an endogenous neuroactive substance.
Yakubutsu, seishin, kōdō = Japanese journal of psychopharmacology 1993;13(3):199-210.
1993: K Sato; F Okumura; Yoshio Goshima; Takeaki Miyamae; Yoshimi Misu
L-dopa potentiates presynaptic inhibitory alpha 2-adrenoceptor- but not facilitatory angiotensin II receptor-mediated modulation of noradrenaline release from rat hypothalamic slices.
Japanese journal of pharmacology 1993;62(1):119-22.
1993: S Nakamura; Yoshio Goshima; J L Yue; Takeaki Miyamae; Yoshimi Misu
Endogenously released DOPA is probably relevant to nicotine-induced increases in locomotor activities of rats.
Japanese journal of pharmacology 1993;62(1):107-10.
1993: Yoshimi Misu; Yoshio Goshima
Is L-dopa an endogenous neurotransmitter?
Trends in pharmacological sciences 1993;14(4):119-23.
1992: J L Yue; Yoshio Goshima; S Nakamura; Yoshimi Misu
L-dopa-like regulatory actions of L-threo-3,4-dihydroxyphenylserine on the release of endogenous noradrenaline via presynaptic receptors in rat hypothalamic slices.
The Journal of pharmacy and pharmacology 1992;44(12):990-5.
1992: N Matsushita; M Kuwahara; Yoshio Goshima; Yoshimi Misu
Effects of nanomolar to submillimolar carteolol on noradrenaline release in the absence and presence of uptake1 and uptake2 blockers in guinea pig pulmonary arteries.
Journal of pharmacobio-dynamics 1992;15(12):687-92.
1992: S Nakamura; Yoshio Goshima; J L Yue; Takeaki Miyamae; Yoshimi Misu
Transmitter-like 3,4-dihydroxyphenylalanine is tonically released by nicotine in striata of conscious rats.
European journal of pharmacology 1992;222(1):75-80.
1992: T Kubo; J L Yue; Yoshio Goshima; S Nakamura; Yoshimi Misu
Evidence for L-dopa systems responsible for cardiovascular control in the nucleus tractus solitarii of the rat.
Neuroscience letters 1992;140(2):153-6.
1992: K Sato; M Kuwahara; Yoshio Goshima; Yoshimi Misu
Coexistence of presynaptic beta 1- and beta 2-adrenoceptors in splenic strips from young rats and betaxolol-induced beta 1-stereoselective antagonism.
Archives internationales de pharmacodynamie et de thérapie 1992;317():47-55.
1992: S Nakamura; Yoshio Goshima; J L Yue; Yoshimi Misu
Transmitter-like basal and K(+)-evoked release of 3,4-dihydroxyphenylalanine from the striatum in conscious rats studied by microdialysis.
Journal of neurochemistry 1992;58(1):270-5.
1991: Yoshio Goshima; S Nakamura; K Ohno; Yoshimi Misu
Picomolar concentrations of L-dopa stereoselectively potentiate activities of presynaptic beta-adrenoceptors to facilitate the release of endogenous noradrenaline from rat hypothalamic slices.
Neuroscience letters 1991;129(2):214-6.
1991: Yoshio Goshima; S Nakamura; Yoshimi Misu
L-dihydroxyphenylalanine methyl ester is a potent competitive antagonist of the L-dihydroxyphenylalanine-induced facilitation of the evoked release of endogenous norepinephrine from rat hypothalamic slices.
The Journal of pharmacology and experimental therapeutics 1991;258(2):466-71.
1991: Yoshio Goshima; Yoshimi Misu; N Arai; K Misugi
Nanomolar L-dopa facilitates release of dopamine via presynaptic beta-adrenoceptors: comparative studies on the actions in striatal slices from control and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mice, an animal model for Parkinson's disease.
Japanese journal of pharmacology 1991;55(1):93-100.
1990: T Kubo; Yoshio Goshima; H Hata; Yoshimi Misu
Evidence that endogenous catecholamines are involved in alpha 2-adrenoceptor-mediated modulation of the aortic baroreceptor reflex in the nucleus tractus solitarii of the rat.
Brain research 1990;526(2):313-7.
1990: Yoshimi Misu; Yoshio Goshima; S Nakamura; T Kubo
Nicotine releases stereoselectively and Ca2(+)-dependently endogenous 3,4-dihydroxyphenylalanine from rat striatal slices.
Brain research 1990;520(1-2):334-7.
1990: N Arai; K Misugi; Yoshio Goshima; Yoshimi Misu
Evaluation of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model for parkinsonism.
Brain research 1990;515(1-2):57-63.
1990: Yoshimi Misu; M Kuwahara; Yoshio Goshima; T Kubo
Stress-induced increases in adrenaline further activate tonically presynaptic beta-adrenoceptors in renal arteries from prehypertensive rats of spontaneously hypertensive strain.
Archives internationales de pharmacodynamie et de thérapie 1990;305():100-10.
1990: Yoshio Goshima; S Nakamura; Yoshimi Misu
L-dopa facilitates the release of endogenous norepinephrine and dopamine via presynaptic beta 1- and beta 2-adrenoceptors under essentially complete inhibition of L-aromatic amino acid decarboxylase in rat hypothalamic slices.
Japanese journal of pharmacology 1990;53(1):47-56.
1990: K Ohno; S Nakamura; Yoshio Goshima; Yoshimi Misu
Carteolol is a useful tool to prove the tonically functioning nature of presynaptic beta-adrenoceptors on peripheral noradrenergic neurons but not on central catecholaminergic neurons.
Japanese journal of pharmacology 1990;52(4):643-6.
1990: Yoshio Goshima; S Nakamura; Yoshimi Misu
L-dopa methyl ester antagonizes competitively L-dopa-induced facilitation of noradrenaline release from rat hypothalamic slices.
Japanese journal of pharmacology 1990;52(1):174-7.
1989: H Amano; Yoshio Goshima; N Akema; H Ueda; T Kubo; Yoshimi Misu
Effects of acute nicotine on catecholamine turnover in various rat brain regions.
Journal of pharmacobio-dynamics 1989;12(1):18-23.
1988: Yoshio Goshima; T Kubo; Yoshimi Misu
Transmitter-like release of endogenous 3,4-dihydroxyphenylalanine from rat striatal slices.
Journal of neurochemistry 1988;50(6):1725-30.