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Frances Gotch

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A Benlahrech; A Coleman; Frances Gotch; A Herasimtschuk; Nesrina Imami; P Kelleher; E Page; S J Westrop; A Yasmin; S Patterson
Dysregulated immunophenotypic attributes of plasmacytoid but not myeloid dendritic cells in HIV-1 infected individuals in the absence of highly active anti-retroviral therapy.
Jennifer Serwanga; Frances Gotch; Laura Heath; Frederick Lyagoba; Susan Mugaba; Susan Nakubulwa; Bridget Nanteza; Nicaise Ndembi; Rebecca N Nsubuga; Edward Pimego; Pontiano Kaleebu
Profile of T cell recognition of HIV type 1 consensus group M Gag and Nef peptides in a clade A1- and D-infected Ugandan population.
Jocelyn S Downey; Brian Gazzard; Frances Gotch; Meriem Attaf; Graeme Moyle; Nesrina Imami
T-cell signalling in antiretroviral-treated, aviraemic HIV-1-positive individuals is present in a raised state of basal activation that contributes to T-cell hyporesponsiveness.

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2012: A Benlahrech; A Coleman; Frances Gotch; A Herasimtschuk; Nesrina Imami; P Kelleher; E Page; S J Westrop; A Yasmin; S Patterson
Dysregulated immunophenotypic attributes of plasmacytoid but not myeloid dendritic cells in HIV-1 infected individuals in the absence of highly active anti-retroviral therapy.
Clinical and experimental immunology 2012;170(2):212-21.
2012: Jennifer Serwanga; Frances Gotch; Laura Heath; Frederick Lyagoba; Susan Mugaba; Susan Nakubulwa; Bridget Nanteza; Nicaise Ndembi; Rebecca N Nsubuga; Edward Pimego; Pontiano Kaleebu
Profile of T cell recognition of HIV type 1 consensus group M Gag and Nef peptides in a clade A1- and D-infected Ugandan population.
AIDS research and human retroviruses 2012;28(4):384-92.
2011: Jocelyn S Downey; Brian Gazzard; Frances Gotch; Meriem Attaf; Graeme Moyle; Nesrina Imami
T-cell signalling in antiretroviral-treated, aviraemic HIV-1-positive individuals is present in a raised state of basal activation that contributes to T-cell hyporesponsiveness.
AIDS (London, England) 2011;25(16):1981-6.
2011: Sally Clark; Tom Ford; Brian G Gazzard; Frances Gotch; Donald C Henderson; Rebecca Metcalf; Mark Nelson; Emma Page; Anton Pozniak; David Asboe; Peter Kelleher
Reduced T(H)1/T(H)17 CD4 T-cell numbers are associated with impaired purified protein derivative-specific cytokine responses in patients with HIV-1 infection.
The Journal of allergy and clinical immunology 2011;128(4):838-846.e5.
2011: Emma Edmonds; Nick Francis; Laurence Game; Frances Gotch; Munther Haddad; Geraint Barton; Sandrine Buisson; MD Dinneen; Christopher Bunker
Gene expression profiling in male genital lichen sclerosus.
International journal of experimental pathology 2011;92(5):320-5.
2011: Jennifer Serwanga; Susan Mugaba; Auma Betty; Edward Pimego; Sarah Walker; Paula Munderi; Charles Gilks; Frances Gotch; Heiner Grosskurth; Jennifer Serwanga
CD8 T-Cell Responses before and after Structured Treatment Interruption in Ugandan Adults Who Initiated ART with CD4 T Cells <200 Cell/μL: The DART Trial STI Substudy.
AIDS research and treatment 2011;2011():875028.
2011: Adel Benlahrech; Frances Gotch; Peter Kelleher; Steven Patterson
Loss of NK stimulatory capacity by plasmacytoid and monocyte-derived DC but not myeloid DC in HIV-1 infected patients.
PloS one 2011;6(3):e17525.
2010: Sai S Duraisingham; Julia Hornig; Frances Gotch; Steven Patterson
CD34-derived human Langerhans cells stimulate a T helper type 2 response independently of extracellular-signal-regulated kinase phosphorylation.
Immunology 2010;131(2):210-9.
2010: Dimitrios Lagos; Gabriel Pollara; Stephen Henderson; Fiona Gratrix; Martin Fabani; Richard S B Milne; Frances Gotch; Chris Boshoff
miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator.
Nature cell biology 2010;12(5):513-9.
2010: Aggeliki Spentzou; Philip Bergin; Dilbinder Gill; Hannah Cheeseman; Ambreen Ashraf; Harry Kaltsidis; Michelle Cashin-Cox; Insiyah Anjarwalla; alan steel; Christopher Higgs; Anton Pozniak; Alicja Piechocka-Trocha; Johnson Wong; Omu Anzala; Etienne Karita; Len Dally; Frances Gotch; Bruce Walker; Jill Gilmour; Peter Hayes
Viral inhibition assay: a CD8 T cell neutralization assay for use in clinical trials of HIV-1 vaccine candidates.
The Journal of infectious diseases 2010;201(5):720-9.
2009: Adel Benlahrech; Julian Harris; Andrea Meiser; Timos Papagatsias; Julia Hornig; Peter Hayes; Andre Lieber; Takis Athanasopoulos; Veronique Bachy; Eszter Csomor; Rod Daniels; Kerry Fisher; Frances Gotch; Len Seymour; Karen Logan; Romina Barbagallo; Linda Klavinskis; George Dickson; Steven Patterson
Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(47):19940-5.
2009: Sai Suda Duraisingham; Julia Hornig; Frances Gotch; Steven Patterson
TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2242-51.
2009: G Rosignoli; C H Lim; mark bower; Frances Gotch; Nesrina Imami
Programmed death (PD)-1 molecule and its ligand PD-L1 distribution among memory CD4 and CD8 T cell subsets in human immunodeficiency virus-1-infected individuals.
Clinical and experimental immunology 2009;157(1):90-7.
2009: Sandrine Buisson; Adel Benlahrech; Brian Gazzard; Frances Gotch; Peter Kelleher; Steven Patterson
Monocyte-derived dendritic cells from HIV type 1-infected individuals show reduced ability to stimulate T cells and have altered production of interleukin (IL)-12 and IL-10.
The Journal of infectious diseases 2009;199(12):1862-71.
2009: Adel Benlahrech; Heather Donaghy; Martin Goodier; Frances Gotch; Linda Klavinskis; George Rozis; Steven Patterson
Human NK Cell Up-regulation of CD69, HLA-DR, Interferon γ Secretion and Cytotoxic Activity by Plasmacytoid Dendritic Cells is Regulated through Overlapping but Different Pathways.
Sensors (Basel, Switzerland) 2009;9(1):386-403.
2008: Dimitrios Lagos; Richard James Vart; Fiona Gratrix; Samantha Jane Westrop; Victoria Emuss; Ping-Pui Wong; Rebecca Robey; Nesrina Imami; mark bower; Frances Gotch; Chris Boshoff
Toll-like receptor 4 mediates innate immunity to Kaposi sarcoma herpesvirus.
Cell host & microbe 2008;4(5):470-83.
2008: George Rozis; Adel Benlahrech; Sai Duraisingham; Frances Gotch; Steven Patterson
Human Langerhans' cells and dermal-type dendritic cells generated from CD34 stem cells express different toll-like receptors and secrete different cytokines in response to toll-like receptor ligands.
Immunology 2008;124(3):329-38.
2008: Timoleon Papagatsias; George Rozis; Takis Athanasopoulos; Frances Gotch; George Dickson; Steven Patterson
Activity of different vaccine-associated promoter elements in human dendritic cells.
Immunology letters 2008;115(2):117-25.
2007: Guglielmo Rosignoli; Alison Cranage; Catherine Burton; Mark Nelson; alan steel; Brian Gazzard; Frances Gotch; Nesrina Imami
Expression of PD-L1, a marker of disease status, is not reduced by HAART in aviraemic patients.
AIDS (London, England) 2007;21(10):1379-81.
2007: Melanie Hart; alan steel; Sally-Ann Clark; Graeme Moyle; Mark Nelson; Don C Henderson; Robert Wilson; Frances Gotch; Brian Gazzard; Peter Kelleher
Loss of discrete memory B cell subsets is associated with impaired immunization responses in HIV-1 infection and may be a risk factor for invasive pneumococcal disease.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):8212-20.
2007: Anthony Kebba; Nesrina Imami; Daniel Bugembe-Lule; David Senkaali; Pontiano Kaleebu; Heiner Grosskurth; Frances Gotch
Recent HIV-1 infection in a high-risk Ugandan cohort: implications for Phase IIB test-of-concept HIV vaccine trials.
Pharmacogenomics 2007;8(4):409-14.
2007: Dimitrios Lagos; Matthew W B Trotter; Richard J Vart; Hsei-Wei Wang; Nick C Matthews; Amy Hansen; Ornella Flore; Frances Gotch; Chris Boshoff
Kaposi sarcoma herpesvirus-encoded vFLIP and vIRF1 regulate antigen presentation in lymphatic endothelial cells.
Blood 2007;109(4):1550-8.
2007: Martin R Goodier; Christopher M Mela; alan steel; Brian Gazzard; mark bower; Frances Gotch
NKG2C+ NK cells are enriched in AIDS patients with advanced-stage Kaposi's sarcoma.
Journal of virology 2007;81(1):430-3.
2006: Nesrina Imami; Anthony Kebba; Frances Gotch
An anniversary without celebration?
Nature immunology 2006;7(9):893.
2006: Catherine T Burton; Frances Gotch; Nesrina Imami
Rapid qualitative and quantitative analysis of T-cell responses in HIV-1-infected individuals receiving successful HAART and HIV-1 sero-negative controls: concomitant assessment of perforin, IFN-gamma and IL-4 secretion.
Journal of immunological methods 2006;308(1-2):216-30.
2005: Frances Gotch; Harvey Holmes; Nesrina Imami
The importance of standardisation of laboratory evaluations in HIV vaccine trials.
Microbes and infection / Institut Pasteur 2005;7(14):1424-32.
2005: Frances Gotch
Therapeutic vaccines and immunotherapy revisited.
Journal of HIV therapy 2005;10(3):48-50.
2005: George Rozis; Shamika de Silva; Adel Benlahrech; Timos Papagatsias; Julian Harris; Frances Gotch; George Dickson; Steve Patterson
Langerhans cells are more efficiently transduced than dermal dendritic cells by adenovirus vectors expressing either group C or group B fibre protein: implications for mucosal vaccines.
European journal of immunology 2005;35(9):2617-26.
2005: Anthony Kebba; Justin Stebbing; Samantha Rowland; Rebecca (Beckie) Jo Ingram; John Agaba; Steve Patterson; Pontiano Kaleebu; Nesrina Imami; Frances Gotch
Expression of the common heat-shock protein receptor CD91 is increased on monocytes of exposed yet HIV-1-seronegative subjects.
Journal of leukocyte biology 2005;78(1):37-42.
2005: Steve Patterson; Heather Donaghy; Parisa Amjadi; Brian Gazzard; Frances Gotch; Peter Kelleher
Human BDCA-1-positive blood dendritic cells differentiate into phenotypically distinct immature and mature populations in the absence of exogenous maturational stimuli: differentiation failure in HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8200-9.
2004: Manyu Prakash; Steve Patterson; Frances Gotch; Moses S Kapembwa
Ex vivo analysis of HIV-1 co-receptors at the endocervical mucosa of women using oral contraceptives.
BJOG : an international journal of obstetrics and gynaecology 2004;111(12):1468-70.
2004: Justin Stebbing; Brian Gazzard; Steve Patterson; mark bower; Mark Nelson; Agamemnon Epenetos; Graham Ogg; Frances Gotch; Philip Savage
Simplified one-step antibody-HLA directed expansion of HIV-specific cytotoxic T lymphocytes: a system suited for use in vivo.
AIDS (London, England) 2004;18(15):2099-101.
2004: Manyu Prakash; Moses S Kapembwa; Frances Gotch; Steve Patterson
Chemokine receptor expression on mucosal dendritic cells from the endocervix of healthy women.
The Journal of infectious diseases 2004;190(2):246-50.
2004: Alleluiah Rutebemberwa; Betty Auma; Jill Gilmour; Gareth Jones; David L Yirrell; Samantha Rowland; Nesrina Imami; Christine Watera; Pontiano Kaleebu; Jimmy Whitworth; Frances Gotch
HIV type 1-specific inter- and intrasubtype cellular immune responses in HIV type 1-infected Ugandans.
AIDS research and human retroviruses 2004;20(7):763-71.
2004: Antonio Pires; Gareth Hardy; Brian Gazzard; Frances Gotch; Nesrina Imami
Initiation of antiretroviral therapy during recent HIV-1 infection results in lower residual viral reservoirs.
Journal of acquired immune deficiency syndromes (1999) 2004;36(3):783-90.
2004: Justin Stebbing; Steve Patterson; Simon Portsmouth; Claire Thomas; Robert Glassman; Adrian Wildfire; Frances Gotch; mark bower; Mark Nelson; Brian Gazzard
Studies on the allostimulatory function of dendritic cells from HCV-HIV-1 co-infected patients.
Cell research 2004;14(3):251-6.
2004: Anthony Kebba; Pontiano Kaleebu; Samantha Rowland; Rebecca (Beckie) Jo Ingram; Jimmy Whitworth; Nesrina Imami; Frances Gotch
Distinct patterns of peripheral HIV-1-specific interferon- gamma responses in exposed HIV-1-seronegative individuals.
The Journal of infectious diseases 2004;189(9):1705-13.
2004: Justin Stebbing; Brian Gazzard; Steve Patterson; mark bower; Dhayaneethie Perumal; Mark Nelson; Andrew McMichael; Graham Ogg; Agamemnon Epenetos; Frances Gotch; Philip Savage
Antibody-targeted MHC complex-directed expansion of HIV-1- and KSHV-specific CD8+ lymphocytes: a new approach to therapeutic vaccination.
Blood 2004;103(5):1791-5.
2004: Antonio Pires; Jeffrey Pido-Lopez; Graeme Moyle; Brian Gazzard; Frances Gotch; Nesrina Imami
Enhanced T-cell maturation, differentiation and function in HIV-1-infected individuals after growth hormone and highly active antiretroviral therapy.
Antiviral therapy 2004;9(1):67-75.
2004: Justin Stebbing; Brian Gazzard; Tom Newsom-Davis; Mark Nelson; Steve Patterson; Frances Gotch; Sundhiya Mandalia; mark bower
Nadir B cell counts are significantly correlated with the risk of Kaposi's sarcoma.
International journal of cancer. Journal international du cancer 2004;108(3):473-4.
2004: Anthony Kebba; Pontiano Kaleebu; Jennifer Serwanga; Samantha Rowland; David L Yirrell; Robert Downing; Jill Gilmour; Nesrina Imami; Frances Gotch; Jimmy Whitworth
HIV type 1 antigen-responsive CD4+ T-lymphocytes in exposed yet HIV Type 1 seronegative Ugandans.
AIDS research and human retroviruses 2004;20(1):67-75.
2004: Simon Portsmouth; Nesrina Imami; A Pires; Justin Stebbing; J Hand; Mark Nelson; Frances Gotch; Brian G Gazzard
Treatment of primary HIV-1 infection with nonnucleoside reverse transcriptase inhibitor-based therapy is effective and well tolerated.
HIV medicine 2004;5(1):26-9.
2003: D Chadwick; Jeffrey Pido-Lopez; A Pires; Nesrina Imami; Frances Gotch; Jorge S Villacian; Sindhu Ravindran; Nicholas Paton
A pilot study of the safety and efficacy of thymosin alpha 1 in augmenting immune reconstitution in HIV-infected patients with low CD4 counts taking highly active antiretroviral therapy.
Clinical and experimental immunology 2003;134(3):477-81.
2003: Martin R Goodier; Nesrina Imami; G Moyle; Brian Gazzard; Frances Gotch
Loss of the CD56hiCD16- NK cell subset and NK cell interferon-gamma production during antiretroviral therapy for HIV-1: partial recovery by human growth hormone.
Clinical and experimental immunology 2003;134(3):470-6.
2003: Justin Stebbing; Adrian Wildfire; Simon Portsmouth; Tom Powles; Christina Thirlwell; P Hewitt; Mark Nelson; Steve Patterson; Sundhiya Mandalia; Frances Gotch; Brian G Gazzard; mark bower
Paclitaxel for anthracycline-resistant AIDS-related Kaposi's sarcoma: clinical and angiogenic correlations.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(11):1660-6.
2003: Justin Stebbing; Brian Gazzard; Ornella Flore; Claire Thomas; Adel Benlahrech; Sundhiya Mandalia; mark bower; Frances Gotch; Steve Patterson
Natural killer cells are not infected by Kaposi's sarcoma-associated herpesvirus in vivo, and natural killer cell counts do not correlate with the risk of developing Kaposi's sarcoma.
AIDS (London, England) 2003;17(13):1998-2000.
2003: Justin Stebbing; Brian Gazzard; Simon Portsmouth; Frances Gotch; Louise Kim; mark bower; Sundhiya Mandalia; Robert Binder; Pramod Srivastava; Steve Patterson
Disease-associated dendritic cells respond to disease-specific antigens through the common heat shock protein receptor.
Blood 2003;102(5):1806-14.
2003: Heather Donaghy; Brian Gazzard; Frances Gotch; Steve Patterson
Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1.
Blood 2003;101(11):4505-11.
2003: Justin Stebbing; Brian Gazzard; Louise Kim; Simon Portsmouth; Adrian Wildfire; Ian Teo; Mark Nelson; mark bower; Frances Gotch; Sunil Shaunak; Pramod Srivastava; Steve Patterson
The heat-shock protein receptor CD91 is up-regulated in monocytes of HIV-1-infected "true" long-term nonprogressors.
Blood 2003;101(10):4000-4.
2003: Justin Stebbing; Simon Portsmouth; Frances Gotch; Brian Gazzard
Kaposi's sarcoma--an update.
International journal of STD & AIDS 2003;14(4):225-7.
2003: Justin Stebbing; Dimitra Bourboulia; Margaret Johnson; Stephen Henderson; Ian Williams; Natalie Wilder; Mervyn Tyrer; Mike Youle; Nesrina Imami; Toru Kobu; Wolfgang Kuon; Joachim Sieper; Frances Gotch; Chris Boshoff
Kaposi's sarcoma-associated herpesvirus cytotoxic T lymphocytes recognize and target Darwinian positively selected autologous K1 epitopes.
Journal of virology 2003;77(7):4306-14.
2003: Ann K Sullivan; Gareth A D Hardy; Mark R Nelson; Frances Gotch; Brian G Gazzard; Nesrina Imami
Interleukin-2-associated viral breakthroughs induce HIV-1-specific CD4 T cell responses in patients on fully suppressive highly active antiretroviral therapy.
AIDS (London, England) 2003;17(4):628-9.
2003: Justin Stebbing; Steve Patterson; Frances Gotch
New insights into the immunology and evolution of HIV.
Cell research 2003;13(1):1-7.
2003: Jeffrey Pido-Lopez; Catherine Burton; Gareth Hardy; Antonio Pires; Ann Sullivan; Brian Gazzard; Richard Aspinall; Frances Gotch; Nesrina Imami
Thymic output during initial highly active antiretroviral therapy (HAART) and during HAART supplementation with interleukin 2 and/or with HIV type 1 immunogen (Remune).
AIDS research and human retroviruses 2003;19(2):103-9.
2003: Manyu Prakash; Steve Patterson; Frances Gotch; Moses S Kapembwa
Recruitment of CD4 T lymphocytes and macrophages into the cervical epithelium of women after coitus.
American journal of obstetrics and gynecology 2003;188(2):376-81.
2002: Jas Gill; Dimitra Bourboulia; John Wilkinson; Peter Hayes; Alethea Cope; Anne-Geneviève Marcelin; Vincent Calvez; Frances Gotch; Chris Boshoff; Brian Gazzard
Prospective study of the effects of antiretroviral therapy on Kaposi sarcoma--associated herpesvirus infection in patients with and without Kaposi sarcoma.
Journal of acquired immune deficiency syndromes (1999) 2002;31(4):384-90.
2002: Nesrina Imami; Antonio Pires; Gareth Hardy; Jamie Wilson; Brian Gazzard; Frances Gotch
A balanced type 1/type 2 response is associated with long-term nonprogressive human immunodeficiency virus type 1 infection.
Journal of virology 2002;76(18):9011-23.
2002: Nesrina Imami; Gareth Hardy; Antonio Pires; Catherine Burton; Jeffrey Pido-Lopez; Christopher M Mela; Frances Gotch
Immune reconstitution in HIV-1-infected patients.
Current opinion in investigational drugs (London, England : 2000) 2002;3(8):1138-45.
2002: Nesrina Imami; Frances Gotch
Mechanisms of loss of HIV-1-specific T-cell responses.
Journal of HIV therapy 2002;7(2):30-4.
2002: Nesrina Imami; Frances Gotch
Prospects for immune reconstitution in HIV-1 infection.
Clinical and experimental immunology 2002;127(3):402-11.
2002: John Wilkinson; Alethea Cope; Jas Gill; Dimitra Bourboulia; Peter Hayes; Nesrina Imami; Toru Kubo; Anne-Geneviève Marcelin; Vincent Calvez; Robin Weiss; Brian Gazzard; Chris Boshoff; Frances Gotch
Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-Infected patients receiving highly active antiretroviral therapy.
Journal of virology 2002;76(6):2634-40.
2002: Manyu Prakash; Moses S Kapembwa; Frances Gotch; Steve Patterson
Oral contraceptive use induces upregulation of the CCR5 chemokine receptor on CD4(+) T cells in the cervical epithelium of healthy women.
Journal of reproductive immunology 2002;54(1-2):117-31.
2002: Jeffrey Pido-Lopez; A Pires; M Nelson; E O'Moore; M Fisher; Brian Gazzard; Richard Aspinall; Frances Gotch; Nesrina Imami
Thymic activity in late-stage HIV-1 infected individuals receiving highly active antiretroviral therapy: potential effect of steroid therapy.
HIV medicine 2002;3(1):56-61.
2001: Nesrina Imami; Gareth Hardy; C Burton; A Pires; Jeffrey Pido-Lopez; R Moss; Brian Gazzard; Frances Gotch
Immune responses and reconstitution in HIV-1 infected individuals: impact of anti-retroviral therapy, cytokines and therapeutic vaccination.
Immunology letters 2001;79(1-2):63-76.
2001: Heather Donaghy; Anton Pozniak; Brian Gazzard; N Qazi; J Gilmour; Frances Gotch; Steve Patterson
Loss of blood CD11c(+) myeloid and CD11c(-) plasmacytoid dendritic cells in patients with HIV-1 infection correlates with HIV-1 RNA virus load.
Blood 2001;98(8):2574-6.
2001: Manyu Prakash; Moses S Kapembwa; Frances Gotch; Steve Patterson
Higher levels of activation markers and chemokine receptors on T lymphocytes in the cervix than peripheral blood of normal healthy women.
Journal of reproductive immunology 2001;52(1-2):101-11.
2001: Nesrina Imami; Gareth Hardy; A Pires; C Burton; A Sullivan; Frances Gotch
Detection and quantification of HIV-1 specific CD4 helper and CD8 cytotoxic cells: their role in HIV-1-infected individuals and vaccine recipients.
HIV medicine 2001;2(3):146-53.
2001: Steve Patterson; A Rae; N Hockey; J Gilmour; Frances Gotch
Plasmacytoid dendritic cells are highly susceptible to human immunodeficiency virus type 1 infection and release infectious virus.
Journal of virology 2001;75(14):6710-3.
2001: Dilys Morgan; Pontiano Kaleebu; Jimmy Whitworth; David L Yirrell; Alleluiah Rutebemberwa; R Shier; B Sebabi; Jill Gilmour; Henry Eotu; N Omoding; Frances Gotch
The stability between two HIV-1 RNA measurements one year apart and the relationship with HIV subtype in rural Uganda.
International journal of STD & AIDS 2001;12(2):116-21.
2001: S Worrell; Jane R Deayton; P Hayes; V C Emery; Frances Gotch; B Gazzard; EL Larsson-Sciard
Molecular correlates in AIDS patients following antiretroviral therapy: diversified T-cell receptor repertoires and in vivo control of cytomegalovirus replication.
HIV medicine 2001;2(1):11-9.
2000: Frances Gotch; Alleluiah Rutebemberwa; G Jones; Nesrina Imami; J Gilmour; Pontiano Kaleebu; Jimmy Whitworth
Vaccines for the control of HIV/AIDS.
Tropical medicine & international health : TM & IH 2000;5(7):A16-21.
1999: Dilys Morgan; Alleluiah Rutebemberwa; SS Malamba; Amanda Ross; Jimmy Whitworth; Pontiano Kaleebu; Frances Gotch
HIV-1 RNA levels in an African population-based cohort and their relation to CD4 lymphocyte counts and World Health Organization clinical staging.
Journal of acquired immune deficiency syndromes (1999) 1999;22(2):167-73.
1999: DJ King; P Amjadi; Richard Tilling; Sabine Kinloch-de-Loes; Clive Loveday; Margaret A Johnson; George Janossy; A Tarragona; Frances Gotch; EL Larsson-Sciard
'Naïve' and 'memory' CD4+ T-cells and T-cell receptor (TCR) V beta repertoire dynamics are independent of the levels of viremia following HIV seroconversion.
Immunology letters 1999;66(1-3):199-206.
1998: Frances Gotch
Cross-clade T cell recognition of HIV.1.
Current opinion in immunology 1998;10(4):388-92.
1996: T Blanchard; S Rowland-Jones; Frances Gotch; Andrew McMichael; G L Smith
Future vaccines for HIV.
Lancet 1996;348(9043):1741.
1996: Frances Gotch; A Gallimore; Andrew McMichael
Cytotoxic T cells--protection from disease progression--protection from infection.
Immunology letters 1996;51(1-2):125-8.
1996: P Krausa; D M Young; Frances Gotch
Identification of a new HLA-A allele (A*2502) by PCR-SSP.
Immunogenetics 1996;45(1):84-5.
1995: S McAdam; Paul Klenerman; L Tussey; S Rowland-Jones; David Lalloo; R Phillips; Anne Edwards; P L F Giangrande; A L Brown; Frances Gotch
Immunogenic HIV variant peptides that bind to HLA-B8 can fail to stimulate cytotoxic T lymphocyte responses.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(5):2729-36.
1995: M Aidoo; Ajit Lalvani; C E Allsopp; Magdalena Plebanski; S J Meisner; P Krausa; M Browning; S Morris-Jones; Frances Gotch; Fidock David
Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria.
Lancet 1995;345(8956):1003-7.
1995: S Rowland-Jones; J Sutton; Koya Ariyoshi; Tao Dong; Frances Gotch; S McAdam; D Whitby; Saihou Sabally; A Gallimore; Tumani Corrah
HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women.
Nature medicine 1995;1(1):59-64.
1995: Andrew McMichael; Paul Klenerman; S Rowland-Jones; Frances Gotch; P Moss
Recognition of viral antigens at the cell surface.
Cancer surveys 1995;22():51-62.
1993: Frances Gotch; S McAdam; C E Allsopp; A Gallimore; J Elvin; M P Kieny; Adrian V S Hill; Andrew J McMichael; Hilton C Whittle
Cytotoxic T cells in HIV2 seropositive Gambians. Identification of a virus-specific MHC-restricted peptide epitope.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(6):3361-9.
1993: S L Rowland-Jones; Douglas F Nixon; M C Aldhous; Frances Gotch; Koya Ariyoshi; N Hallam; J S Kroll; Karin Froebel; Andrew McMichael
HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant.
Lancet 1993;341(8849):860-1.
1993: Frances Gotch; D Nixon; A Gallimore; S McAdam; Andrew McMichael
Cytotoxic T lymphocyte epitopes shared between HIV-1, HIV-2, and SIV.
Journal of medical primatology 1993;22(2-3):119-23.
1993: J Sutton; S Rowland-Jones; W Rosenberg; D Nixon; Frances Gotch; X M Gao; N Murray; A Spoonas; P Driscoll; M Smith
A sequence pattern for peptides presented to cytotoxic T lymphocytes by HLA B8 revealed by analysis of epitopes and eluted peptides.
European journal of immunology 1993;23(2):447-53.
1992: J Morrison; J Elvin; F Latron; Frances Gotch; R Moots; Jack L Strominger; Andrew McMichael
Identification of the nonamer peptide from influenza A matrix protein and the role of pockets of HLA-A2 in its recognition by cytotoxic T lymphocytes.
European journal of immunology 1992;22(4):903-7.
1990: Vincenzo Cerundolo; J Alexander; K Anderson; C Lamb; P Cresswell; Andrew McMichael; Frances Gotch; A Townsend
Presentation of viral antigen controlled by a gene in the major histocompatibility complex.
Nature 1990;345(6274):449-52.
1989: H Bodmer; G Ogg; Frances Gotch; Andrew McMichael
Anti-HLA-A2 antibody-enhancement of peptide association with HLA-A2 as detected by cytotoxic T lymphocytes.
Nature 1989;342(6248):443-6.
1989: A Townsend; J Bastin; H Bodmer; George G Brownlee; J Davey; Frances Gotch; K Gould; I Jones; Andrew McMichael; J Rothbard
Recognition of influenza virus proteins by cytotoxic T lymphocytes.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1989;323(1217):527-33.
1988: Frances Gotch; Andrew McMichael; J Rothbard
Recognition of influenza A matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site.
The Journal of experimental medicine 1988;168(6):2045-57.
1987: C G Potter; Frances Gotch; G T Warner; J Oestrup
Lymphocyte proliferation and cytotoxic assays using flat-bed scintillation counting.
Journal of immunological methods 1987;105(2):171-7.
1987: Frances Gotch; J Rothbard; K Howland; A Townsend; Andrew McMichael
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2.
Nature 1987;326(6116):881-2.