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Yuji Goto

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Hirotsugu Ogi; Kentaro Uesugi; Hisashi Yagi; Masahiko Fukushima; Yuji Goto; Masahiko Hirao
Acceleration of deposition of Aβ(1-40) peptide on ultrasonically formed Aβ(1-42) nucleus studied by wireless quartz-crystal-microbalance biosensor.
Tsuyoshi Konuma; Young-Ho Lee; Yuji Goto; Kazumasa Sakurai
Principal component analysis of chemical shift perturbation data of a multiple-ligand-binding system for elucidation of respective binding mechanism.
Young-Ho Lee; Yuji Goto
Kinetic intermediates of amyloid fibrillation studied by hydrogen exchange methods with nuclear magnetic resonance.

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2013: Hirotsugu Ogi; Kentaro Uesugi; Hisashi Yagi; Masahiko Fukushima; Yuji Goto; Masahiko Hirao
Acceleration of deposition of Aβ(1-40) peptide on ultrasonically formed Aβ(1-42) nucleus studied by wireless quartz-crystal-microbalance biosensor.
Biosensors & bioelectronics 2013;40(1):200-5.
2013: Tsuyoshi Konuma; Young-Ho Lee; Yuji Goto; Kazumasa Sakurai
Principal component analysis of chemical shift perturbation data of a multiple-ligand-binding system for elucidation of respective binding mechanism.
Proteins 2013;81(1):107-18.
2012: Young-Ho Lee; Yuji Goto
Kinetic intermediates of amyloid fibrillation studied by hydrogen exchange methods with nuclear magnetic resonance.
Biochimica et biophysica acta 2012;1824(12):1307-23.
2012: Toshinori Shimanouchi; Naoya Shimauchi; Hiroshi Umakoshi; Hisashi Yagi; Yuji Goto; Nachi Kitaura; Ryo Ohnishi; Ryoichi Kuboi
Formation of spherulitic amyloid β aggregate by anionic liposomes.
Biochemical and biophysical research communications 2012;426(2):165-71.
2012: Kotaro Yanagi; Yuichi Yoshimura; Takahisa Ikegami; Tsuyoshi Konuma; Young-Ho Lee; Hironobu Naiki; Kazumasa Sakurai; Kenji Sugase; Yuji Goto
The monomer-seed interaction mechanism in the formation of the β2-microglobulin amyloid fibril clarified by solution NMR techniques.
Journal of molecular biology 2012;422(3):390-402.
2012: Yuichi Yoshimura; Hiroki Kitayama; Young-Ho Lee; Yuxi Lin; Hironobu Naiki; Hirotsugu Ogi; Kazumasa Sakurai; Masatomo So; Hisashi Yagi; Yuji Goto
Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(36):14446-51.
2012: Mototaka Suzuki; Keiichi Yokoyama; Takahisa Ikegami; Young-Ho Lee; Kazumasa Sakurai; Yuji Goto
A back hydrogen exchange procedure via the acid-unfolded state for a large protein.
Biochemistry 2012;51(28):5564-70.
2011: Masatomo So; Hisashi Yagi; Hironobu Naiki; Hirotsugu Ogi; Kazumasa Sakurai; Yuji Goto
Ultrasonication-dependent acceleration of amyloid fibril formation.
Journal of molecular biology 2011;412(4):568-77.
2011: Young-Ho Lee; Kazumasa Sakurai; Daron M Standley; Toshiharu Hase; Takahisa Ikegami; Yuji Goto
Binding energetics of ferredoxin-NADP+ reductase with ferredoxin and its relation to function.
Chembiochem : a European journal of chemical biology 2011;12(13):2062-70.
2011: Kazumasa Sakurai; Masanori Yagi; Shunsuke Fujioka; Tsuyoshi Konuma; Yuji Goto
A circumventing role for the non-native intermediate in the folding of β-lactoglobulin.
Biochemistry 2011;50(29):6498-507.
2011: Kotaro Yanagi; Mizue Ashizaki; Young-Ho Lee; Kazumasa Sakurai; Hisashi Yagi; Yuji Goto
Hexafluoroisopropanol induces amyloid fibrils of islet amyloid polypeptide by enhancing both hydrophobic and electrostatic interactions.
The Journal of biological chemistry 2011;286(27):23959-66.
2011: Isao Suetake; Hideyuki Takeshima; Yuji Goto; Takahisa Ikegami; Hironobu Kimura; Young-Ho Lee; Yuichi Mishima; Shoji Tajima
Characterization of DNA-binding activity in the N-terminal domain of the DNA methyltransferase Dnmt3a.
The Biochemical journal 2011;437(1):141-8.
2011: Hirotsugu Ogi; Kentaro Uesugi; Hisashi Yagi; Taiji Yanagida; Yuji Fukunishi; Masahiko Fukushima; Yuji Goto; Masahiko Hirao
Seed-dependent deposition behavior of Aβ peptides studied with wireless quartz-crystal-microbalance biosensor.
Analytical chemistry 2011;83(12):4982-8.
2011: Daisaku Ozawa; Yuichi Kaji; Hisashi Yagi; Kazumasa Sakurai; Toru Kawakami; Hironobu Naiki; Yuji Goto
Destruction of amyloid fibrils of keratoepithelin peptides by laser irradiation coupled with amyloid-specific thioflavin T.
The Journal of biological chemistry 2011;286(12):10856-63.
2011: Daisaku Ozawa; Kazuhiro Hasegawa; Young-Ho Lee; Kazumasa Sakurai; Kotaro Yanagi; Tadakazu Ookoshi; Yuji Goto; Hironobu Naiki
Inhibition of beta2-microglobulin amyloid fibril formation by alpha2-macroglobulin.
The Journal of biological chemistry 2011;286(11):9668-76.
2011: Tsuyoshi Konuma; Tetsunari Kimura; Shuzo Matsumoto; Yuji Goto; Tetsuro Fujisawa; Alan R Fersht; Satoshi Takahashi
Time-resolved small-angle X-ray scattering study of the folding dynamics of barnase.
Journal of molecular biology 2011;405(5):1284-94.
2011: Tsuyoshi Konuma; Eri Chatani; Masanori Yagi; Kazumasa Sakurai; Takahisa Ikegami; Hironobu Naiki; Yuji Goto
Kinetic intermediates of β(2)-microglobulin fibril elongation probed by pulse-labeling H/D exchange combined with NMR analysis.
Journal of molecular biology 2011;405(3):851-62.
2011: Chai L Teoh; Hisashi Yagi; Michael D W Griffin; Yuji Goto; Geoffrey J Howlett
Visualization of polymorphism in apolipoprotein C-II amyloid fibrils.
Journal of biochemistry 2011;149(1):67-74.
2010: Yuichi Yoshimura; Kazumasa Sakurai; Young-Ho Lee; Takahisa Ikegami; Eri Chatani; Hironobu Naiki; Yuji Goto
Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy.
Protein science : a publication of the Protein Society 2010;19(12):2347-55.
2010: Hisashi Yagi; Hideki Takeuchi; Shiho Ogawa; Naomi Ito; Isao Sakane; Kunihiro Hongo; Tomohiro Mizobata; Yuji Goto; Yasushi Kawata
Isolation of short peptide fragments from alpha-synuclein fibril core identifies a residue important for fibril nucleation: a possible implication for diagnostic applications.
Biochimica et biophysica acta 2010;1804(10):2077-87.
2010: Takahiro Yamaguchi; Hisashi Yagi; Yuji Goto; Katsumi Matsuzaki; Masaru Hoshino
A disulfide-linked amyloid-beta peptide dimer forms a protofibril-like oligomer through a distinct pathway from amyloid fibril formation.
Biochemistry 2010;49(33):7100-7.
2010: Kaori Yamamoto; Hisashi Yagi; Young-Ho Lee; József Kardos; Yoshihisa Hagihara; Hironobu Naiki; Yuji Goto
The amyloid fibrils of the constant domain of immunoglobulin light chain.
FEBS letters 2010;584(15):3348-53.
2010: Eri Chatani; Reina Ohnishi; Tsuyoshi Konuma; Kazumasa Sakurai; Hironobu Naiki; Yuji Goto
Pre-steady-state kinetic analysis of the elongation of amyloid fibrils of beta(2)-microglobulin with tryptophan mutagenesis.
Journal of molecular biology 2010;400(5):1057-66.
2010: Hisashi Yagi; Daisaku Ozawa; Kazumasa Sakurai; Toru Kawakami; Hiroki Kuyama; Osamu Nishimura; Toshinori Shimanouchi; Ryoichi Kuboi; Hironobu Naiki; Yuji Goto
Laser-induced propagation and destruction of amyloid beta fibrils.
The Journal of biological chemistry 2010;285(25):19660-7.
2010: Vu Thi Huong; Toshinori Shimanouchi; Naoya Shimauchi; Hisashi Yagi; Hiroshi Umakoshi; Yuji Goto; Ryoichi Kuboi
Catechol derivatives inhibit the fibril formation of amyloid-beta peptides.
Journal of bioscience and bioengineering 2010;109(6):629-34.
2010: Akiyoshi Morinaga; Kazuhiro Hasegawa; Ryo Nomura; Tadakazu Ookoshi; Daisaku Ozawa; Yuji Goto; Masahito Yamada; Hironobu Naiki
Critical role of interfaces and agitation on the nucleation of Abeta amyloid fibrils at low concentrations of Abeta monomers.
Biochimica et biophysica acta 2010;1804(4):986-95.
2009: Yuji Goto; Hiroshi Kimura
Inactive X chromosome-specific histone H3 modifications and CpG hypomethylation flank a chromatin boundary between an X-inactivated and an escape gene.
Nucleic acids research 2009;37(22):7416-28.
2009: Young-Ho Lee; Daisaku Ozawa; Yuji Goto
[New world of amyloid science].
Seikagaku. The Journal of Japanese Biochemical Society 2009;81(8):677-87.
2009: Atsushi Kameda; Eugene Hayato Morita; Kazumasa Sakurai; Hironobu Naiki; Yuji Goto
NMR-based characterization of a refolding intermediate of beta2-microglobulin labeled using a wheat germ cell-free system.
Protein science : a publication of the Protein Society 2009;18(8):1592-601.
2009: Eri Chatani; Young-Ho Lee; Hisashi Yagi; Yuichi Yoshimura; Hironobu Naiki; Yuji Goto
Ultrasonication-dependent production and breakdown lead to minimum-sized amyloid fibrils.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(27):11119-24.
2009: Kenji Sasahara; Hisashi Yagi; Hironobu Naiki; Yuji Goto
Thermal response with exothermic effects of beta2-microglobulin amyloid fibrils and fibrillation.
Journal of molecular biology 2009;389(3):584-94.
2009: Kazumasa Sakurai; Tsuyoshi Konuma; Masanori Yagi; Yuji Goto
Structural dynamics and folding of beta-lactoglobulin probed by heteronuclear NMR.
Biochimica et biophysica acta 2009;1790(6):527-37.
2009: Young-Ho Lee; Eri Chatani; Kenji Sasahara; Hironobu Naiki; Yuji Goto
A comprehensive model for packing and hydration for amyloid fibrils of beta2-microglobulin.
The Journal of biological chemistry 2009;284(4):2169-75.
2009: Daisaku Ozawa; Hisashi Yagi; Tadato Ban; Atsushi Kameda; Toru Kawakami; Hironobu Naiki; Yuji Goto
Destruction of amyloid fibrils of a beta2-microglobulin fragment by laser beam irradiation.
The Journal of biological chemistry 2009;284(2):1009-17.
2008: Kazuhiro Hasegawa; Shinobu Tsutsumi-Yasuhara; Tadakazu Ookoshi; Yumiko Ohhashi; Hideki Kimura; Naoki Takahashi; Haruyoshi Yoshida; Ryoichi Miyazaki; Yuji Goto; Hironobu Naiki
Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH.
The Biochemical journal 2008;416(2):307-15.
2008: Michiko Sakata; Eri Chatani; Atsushi Kameda; Kazumasa Sakurai; Hironobu Naiki; Yuji Goto
Kinetic coupling of folding and prolyl isomerization of beta2-microglobulin studied by mutational analysis.
Journal of molecular biology 2008;382(5):1242-55.
2008: Tadakazu Ookoshi; Kazuhiro Hasegawa; Yumiko Ohhashi; Hideki Kimura; Naoki Takahashi; Haruyoshi Yoshida; Ryoichi Miyazaki; Yuji Goto; Hironobu Naiki
Lysophospholipids induce the nucleation and extension of beta2-microglobulin-related amyloid fibrils at a neutral pH.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2008;23(10):3247-55.
2008: Tetsunari Kimura; Akio Maeda; Shingo Nishiguchi; Koichiro Ishimori; Isao Morishima; Takashi Konno; Yuji Goto; Satoshi Takahashi
Dehydration of main-chain amides in the final folding step of single-chain monellin revealed by time-resolved infrared spectroscopy.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13391-6.
2008: Masanori Yagi; Atsushi Kameda; Kazumasa Sakurai; Chiaki Nishimura; Yuji Goto
Disulfide-linked bovine beta-lactoglobulin dimers fold slowly, navigating a glassy folding landscape.
Biochemistry 2008;47(22):5996-6006.
2008: Kenji Sasahara; Hisashi Yagi; Miyo Sakai; Hironobu Naiki; Yuji Goto
Amyloid nucleation triggered by agitation of beta2-microglobulin under acidic and neutral pH conditions.
Biochemistry 2008;47(8):2650-60.
2008: Kaori Yamamoto; Hisashi Yagi; Daisaku Ozawa; Kenji Sasahara; Hironobu Naiki; Yuji Goto
Thiol compounds inhibit the formation of amyloid fibrils by beta 2-microglobulin at neutral pH.
Journal of molecular biology 2008;376(1):258-68.
2008: Hiroshi Kimura; Yoko Hayashi-Takanaka; Yuji Goto; Nanako Takizawa; Naohito Nozaki
The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies.
Cell structure and function 2008;33(1):61-73.
2007: Hisashi Yagi; Tadato Ban; Kenichi Morigaki; Hironobu Naiki; Yuji Goto
Visualization and classification of amyloid beta supramolecular assemblies.
Biochemistry 2007;46(51):15009-17.
2007: Shingo Nishiguchi; Yuji Goto; Satoshi Takahashi
Solvation and desolvation dynamics in apomyoglobin folding monitored by time-resolved infrared spectroscopy.
Journal of molecular biology 2007;373(2):491-502.
2007: Kenji Sasahara; Hisashi Yagi; Hironobu Naiki; Yuji Goto
Heat-induced conversion of beta(2)-microglobulin and hen egg-white lysozyme into amyloid fibrils.
Journal of molecular biology 2007;372(4):981-91.
2007: Kazumasa Sakurai; Yuji Goto
Principal component analysis of the pH-dependent conformational transitions of bovine beta-lactoglobulin monitored by heteronuclear NMR.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(39):15346-51.
2007: Kentaro Iwata; Takanori Matsuura; Kazumasa Sakurai; Atsushi Nakagawa; Yuji Goto
High-resolution crystal structure of beta2-microglobulin formed at pH 7.0.
Journal of biochemistry 2007;142(3):413-9.
2007: Masaru Hoshino; Hidenori Katou; Kei-ichi Yamaguchi; Yuji Goto
Dimethylsulfoxide-quenched hydrogen/deuterium exchange method to study amyloid fibril structure.
Biochimica et biophysica acta 2007;1768(8):1886-99.
2007: Masahito Kinoshita; Kiyoto Kamagata; Akio Maeda; Yuji Goto; Tamiki Komatsuzaki; Satoshi Takahashi
Development of a technique for the investigation of folding dynamics of single proteins for extended time periods.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10453-8.
2007: Tsuyoshi Konuma; Kazumasa Sakurai; Yuji Goto
Promiscuous binding of ligands by beta-lactoglobulin involves hydrophobic interactions and plasticity.
Journal of molecular biology 2007;368(1):209-18.
2007: Shuzo Matsumoto; Akira Yane; Satoru Nakashima; Masaki Hashida; Masayuki Fujita; Yuji Goto; Satoshi Takahashi
A rapid flow mixer with 11-mus mixing time microfabricated by a pulsed-laser ablation technique: observation of a barrier-limited collapse in cytochrome c folding.
Journal of the American Chemical Society 2007;129(13):3840-1.
2007: Yoshitaka Nagai; Takashi Inui; H Akiko Popiel; Nobuhiro Fujikake; Kazuhiro Hasegawa; Yoshihiro Urade; Yuji Goto; Hironobu Naiki; Tatsushi Toda
A toxic monomeric conformer of the polyglutamine protein.
Nature structural & molecular biology 2007;14(4):332-40.
2007: Rumi Adachi; Kei-ichi Yamaguchi; Hisashi Yagi; Kazumasa Sakurai; Hironobu Naiki; Yuji Goto
Flow-induced alignment of amyloid protofilaments revealed by linear dichroism.
The Journal of biological chemistry 2007;282(12):8978-83.
2007: Kenji Sasahara; Hisashi Yagi; Hironobu Naiki; Yuji Goto
Heat-triggered conversion of protofibrils into mature amyloid fibrils of beta2-microglobulin.
Biochemistry 2007;46(11):3286-93.
2007: Young-Ho Lee; Kosuke Tamura; Masahiro Maeda; Masaru Hoshino; Kazumasa Sakurai; Satoshi Takahashi; Takahisa Ikegami; Toshiharu Hase; Yuji Goto
Cores and pH-dependent dynamics of ferredoxin-NADP+ reductase revealed by hydrogen/deuterium exchange.
The Journal of biological chemistry 2007;282(8):5959-67.
2006: Kentaro Iwata; Toshimichi Fujiwara; Yasushi Matsuki; Hideo Akutsu; Satoshi Takahashi; Hironobu Naiki; Yuji Goto
3D structure of amyloid protofilaments of beta2-microglobulin fragment probed by solid-state NMR.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18119-24.
2006: Daron M Standley; Yasushige Yonezawa; Yuji Goto; Haruki Nakamura
Flexible docking of an amyloid-forming peptide from beta(2)-microglobulin.
FEBS letters 2006;580(26):6199-205.
2006: Tadato Ban; Kenichi Morigaki; Hisashi Yagi; Takashi Kawasaki; Atsuko Kobayashi; Shunsuke Yuba; Hironobu Naiki; Yuji Goto
Real-time and single fibril observation of the formation of amyloid beta spherulitic structures.
The Journal of biological chemistry 2006;281(44):33677-83.
2006: Kei-ichi Yamaguchi; Hironobu Naiki; Yuji Goto
Mechanism by which the amyloid-like fibrils of a beta 2-microglobulin fragment are induced by fluorine-substituted alcohols.
Journal of molecular biology 2006;363(1):279-88.
2006: Miho Kihara; Eri Chatani; Kentaro Iwata; Kaori Yamamoto; Takanori Matsuura; Atsushi Nakagawa; Hironobu Naiki; Yuji Goto
Conformation of amyloid fibrils of beta2-microglobulin probed by tryptophan mutagenesis.
The Journal of biological chemistry 2006;281(41):31061-9.
2006: Tadato Ban; Keiichi Yamaguchi; Yuji Goto
Direct observation of amyloid fibril growth, propagation, and adaptation.
Accounts of chemical research 2006;39(9):663-70.
2006: Kenji Sasahara; Hironobu Naiki; Yuji Goto
Exothermic effects observed upon heating of beta2-microglobulin monomers in the presence of amyloid seeds.
Biochemistry 2006;45(29):8760-9.
2006: Eri Chatani; Hironobu Naiki; Yuji Goto
Seeding-dependent propagation and maturation of beta2-microglobulin amyloid fibrils under high pressure.
Journal of molecular biology 2006;359(4):1086-96.
2006: Kazumasa Sakurai; Yuji Goto
Dynamics and mechanism of the Tanford transition of bovine beta-lactoglobulin studied using heteronuclear NMR spectroscopy.
Journal of molecular biology 2006;356(2):483-96.
2006: Tadato Ban; Yuji Goto
Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy.
Methods in enzymology 2006;413():91-102.
2005: Eri Chatani; Yuji Goto
Structural stability of amyloid fibrils of beta(2)-microglobulin in comparison with its native fold.
Biochimica et biophysica acta 2005;1753(1):64-75.
2005: Kei-Ichi Yamaguchi; Satoshi Takahashi; Tomoji Kawai; Hironobu Naiki; Yuji Goto
Seeding-dependent propagation and maturation of amyloid fibril conformation.
Journal of molecular biology 2005;352(4):952-60.
2005: Eri Chatani; Michiko Kato; Tomoji Kawai; Hironobu Naiki; Yuji Goto
Main-chain dominated amyloid structures demonstrated by the effect of high pressure.
Journal of molecular biology 2005;352(4):941-51.
2005: Kenji Sasahara; Hironobu Naiki; Yuji Goto
Kinetically controlled thermal response of beta2-microglobulin amyloid fibrils.
Journal of molecular biology 2005;352(3):700-11.
2005: Yumiko Ohhashi; Miho Kihara; Hironobu Naiki; Yuji Goto
Ultrasonication-induced amyloid fibril formation of beta2-microglobulin.
The Journal of biological chemistry 2005;280(38):32843-8.
2005: Masahiro Maeda; Young Ho Lee; Takahisa Ikegami; Kohsuke Tamura; Masaru Hoshino; Toshio Yamazaki; Masato Nakayama; Toshiharu Hase; Yuji Goto
Identification of the N- and C-terminal substrate binding segments of ferredoxin-NADP+ reductase by NMR.
Biochemistry 2005;44(31):10644-53.
2005: Atsushi Kameda; Masaru Hoshino; Takashi Higurashi; Satoshi Takahashi; Hironobu Naiki; Yuji Goto
Nuclear magnetic resonance characterization of the refolding intermediate of beta2-microglobulin trapped by non-native prolyl peptide bond.
Journal of molecular biology 2005;348(2):383-97.
2005: Bakthisaran Raman; Tadato Ban; Kei-Ichi Yamaguchi; Miyo Sakai; Tomoji Kawai; Hironobu Naiki; Yuji Goto
Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide.
The Journal of biological chemistry 2005;280(16):16157-62.
2005: Miho Kihara; Eri Chatani; Miyo Sakai; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Seeding-dependent maturation of beta2-microglobulin amyloid fibrils at neutral pH.
The Journal of biological chemistry 2005;280(12):12012-8.
2005: Hironobu Naiki; Suguru Yamamoto; Kazuhiro Hasegawa; Itaru Yamaguchi; Yuji Goto; Fumitake Gejyo
Molecular interactions in the formation and deposition of beta2-microglobulin-related amyloid fibrils.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2005;12(1):15-25.
2005: Furukawa Yoshiaki; Tadato Ban; Daizo Hamada; Koichiro Ishimori; Yuji Goto; Isao Morishima
Electron transfer reaction in a single protein molecule observed by total internal reflection fluorescence microscopy.
Journal of the American Chemical Society 2005;127(7):2098-103.
2005: Tomoaki Kato; Yuji Goto; Kazuhisa Ono; Makoto Hayashi; Yoshikatsu Murooka
Expression of a major house dust mite allergen gene from Dermatophagoides farinae in Lotus japonicus accession Miyakojima MG-20.
Journal of bioscience and bioengineering 2005;99(2):165-8.
2005: Takashi Kanno; Keiichi Yamaguchi; Hironobu Naiki; Yuji Goto; Tomoji Kawai
Association of thin filaments into thick filaments revealing the structural hierarchy of amyloid fibrils.
Journal of structural biology 2005;149(2):213-8.
2005: Bakthisaran Raman; Eri Chatani; Miho Kihara; Tadato Ban; Miyo Sakai; Kazuhiro Hasegawa; Hironobu Naiki; Ch Mohan Rao; Yuji Goto
Critical balance of electrostatic and hydrophobic interactions is required for beta 2-microglobulin amyloid fibril growth and stability.
Biochemistry 2005;44(4):1288-99.
2005: Hiromasa Wadai; Kei-ichi Yamaguchi; Satoshi Takahashi; Takashi Kanno; Tomoji Kawai; Hironobu Naiki; Yuji Goto
Stereospecific amyloid-like fibril formation by a peptide fragment of beta2-microglobulin.
Biochemistry 2005;44(1):157-64.
2004: József Kardos; Kaori Yamamoto; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Direct measurement of the thermodynamic parameters of amyloid formation by isothermal titration calorimetry.
The Journal of biological chemistry 2004;279(53):55308-14.
2004: Tadato Ban; Masaru Hoshino; Satoshi Takahashi; Daizo Hamada; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Direct observation of Abeta amyloid fibril growth and inhibition.
Journal of molecular biology 2004;344(3):757-67.
2004: Takehiro Narimoto; Kazumasa Sakurai; Azusa Okamoto; Eri Chatani; Masaru Hoshino; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Conformational stability of amyloid fibrils of beta2-microglobulin probed by guanidine-hydrochloride-induced unfolding.
FEBS letters 2004;576(3):313-9.
2004: Suguru Yamamoto; Kazuhiro Hasegawa; Itaru Yamaguchi; Shinobu Tsutsumi; József Kardos; Yuji Goto; Fumitake Gejyo; Hironobu Naiki
Low concentrations of sodium dodecyl sulfate induce the extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.
Biochemistry 2004;43(34):11075-82.
2004: Kei-ichi Yamaguchi; Hidenori Katou; Masaru Hoshino; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Core and heterogeneity of beta2-microglobulin amyloid fibrils as revealed by H/D exchange.
Journal of molecular biology 2004;338(3):559-71.
2004: Yumiko Ohhashi; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Optimum amyloid fibril formation of a peptide fragment suggests the amyloidogenic preference of beta2-microglobulin under physiological conditions.
The Journal of biological chemistry 2004;279(11):10814-21.
2004: James Villanueva; Masaru Hoshino; Hidenori Katou; József Kardos; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Increase in the conformational flexibility of beta 2-microglobulin upon copper binding: a possible role for copper in dialysis-related amyloidosis.
Protein science : a publication of the Protein Society 2004;13(3):797-809.
2004: Suguru Yamamoto; Itaru Yamaguchi; Kazuhiro Hasegawa; Shinobu Tsutsumi; Yuji Goto; Fumitake Gejyo; Hironobu Naiki
Glycosaminoglycans enhance the trifluoroethanol-induced extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.
Journal of the American Society of Nephrology : JASN 2004;15(1):126-33.
2004: Nobuhiko Tokuriki; Masataka Kinjo; Shigeru Negi; Masaru Hoshino; Yuji Goto; Itaru Urabe; Tetsuya Yomo
Protein folding by the effects of macromolecular crowding.
Protein science : a publication of the Protein Society 2004;13(1):125-33.
2003: Masanori Yagi; Kazumasa Sakurai; Chitkala Kalidas; Carl A Batt; Yuji Goto
Reversible unfolding of bovine beta-lactoglobulin mutants without a free thiol group.
The Journal of biological chemistry 2003;278(47):47009-15.
2003: Takeshi Chiba; Yoshihisa Hagihara; Takashi Higurashi; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Amyloid fibril formation in the context of full-length protein: effects of proline mutations on the amyloid fibril formation of beta2-microglobulin.
The Journal of biological chemistry 2003;278(47):47016-24.
2003: Nami Hirota-Nakaoka; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Dissolution of beta2-microglobulin amyloid fibrils by dimethylsulfoxide.
Journal of biochemistry 2003;134(1):159-64.
2003: Masayo Gozu; Young Ho Lee; Yumiko Ohhashi; Masaru Hoshino; Hironobu Naiki; Yuji Goto
Conformational dynamics of beta(2)-microglobulin analyzed by reduction and reoxidation of the disulfide bond.
Journal of biochemistry 2003;133(6):731-6.
2003: Tadato Ban; Daizo Hamada; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence.
The Journal of biological chemistry 2003;278(19):16462-5.
2003: Kazuhiro Hasegawa; Yumiko Ohhashi; Itaru Yamaguchi; Naoki Takahashi; Shinobu Tsutsumi; Yuji Goto; Fumitake Gejyo; Hironobu Naiki
Amyloidogenic synthetic peptides of beta2-microglobulin--a role of the disulfide bond.
Biochemical and biophysical research communications 2003;304(1):101-6.
2002: Masayo Gozu; Masaru Hoshino; Takashi Higurashi; Hisao Kato; Yuji Goto
The interaction of beta(2)-glycoprotein I domain V with chaperonin GroEL: the similarity with the domain V and membrane interaction.
Protein science : a publication of the Protein Society 2002;11(12):2792-803.
2002: Hidenori Katou; Takashi Kanno; Masaru Hoshino; Yoshihisa Hagihara; Hiroyuki Tanaka; Tomoji Kawai; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
The role of disulfide bond in the amyloidogenic state of beta(2)-microglobulin studied by heteronuclear NMR.
Protein science : a publication of the Protein Society 2002;11(9):2218-29.
2002: Kazumasa Sakurai; Yuji Goto
Manipulating monomer-dimer equilibrium of bovine Beta -lactoglobulin by amino acid substitution.
The Journal of biological chemistry 2002;277(28):25735-40.
2002: Dong-Pyo Hong; Masayo Gozu; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Conformation of beta 2-microglobulin amyloid fibrils analyzed by reduction of the disulfide bond.
The Journal of biological chemistry 2002;277(24):21554-60.
2002: Masahiro Maeda; Daizo Hamada; Masaru Hoshino; Yayoi Onda; Toshiharu Hase; Yuji Goto
Partially folded structure of flavin adenine dinucleotide-depleted ferredoxin-NADP+ reductase with residual NADP+ binding domain.
The Journal of biological chemistry 2002;277(19):17101-7.
2002: Masaru Hoshino; Hidenori Katou; Yoshihisa Hagihara; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange.
Nature structural biology 2002;9(5):332-6.
2002: Yoshihisa Hagihara; Dong-Pyo Hong; Masaru Hoshino; Kei-ichi Enjyoji; Hisao Kato; Yuji Goto
Aggregation of beta(2)-glycoprotein I induced by sodium lauryl sulfate and lysophospholipids.
Biochemistry 2002;41(3):1020-6.
2002: Gennady V Kozhukh; Yoshihisa Hagihara; Toru Kawakami; Kazuhiro Hasegawa; Hironobu Naiki; Yuji Goto
Investigation of a peptide responsible for amyloid fibril formation of beta 2-microglobulin by achromobacter protease I.
The Journal of biological chemistry 2002;277(2):1310-5.
2002: Yumiko Ohhashi; Yoshihisa Hagihara; Gennady V Kozhukh; Masaru Hoshino; Kazuhiro Hasegawa; Itaru Yamaguchi; Hironobu Naiki; Yuji Goto
The intrachain disulfide bond of beta(2)-microglobulin is not essential for the immunoglobulin fold at neutral pH, but is essential for amyloid fibril formation at acidic pH.
Journal of biochemistry 2002;131(1):45-52.
2001: Kazumasa Sakurai; Motohisa Oobatake; Yuji Goto
Salt-dependent monomer-dimer equilibrium of bovine beta-lactoglobulin at pH 3.
Protein science : a publication of the Protein Society 2001;10(11):2325-35.
2001: Dong-Pyo Hong; Yoshihisa Hagihara; Hisao Kato; Yuji Goto
Flexible loop of beta 2-glycoprotein I domain V specifically interacts with hydrophobic ligands.
Biochemistry 2001;40(27):8092-100.
2001: Hidenori Katou; Masaru Hoshino; Hironari Kamikubo; Carl A Batt; Yuji Goto
Native-like beta-hairpin retained in the cold-denatured state of bovine beta-lactoglobulin.
Journal of molecular biology 2001;310(2):471-84.
2001: K Kuwata; H Li; H Yamada; Carl A Batt; Yuji Goto; Kazuyuki Akasaka
High pressure NMR reveals a variety of fluctuating conformers in beta-lactoglobulin.
Journal of molecular biology 2001;305(5):1073-83.
2001: K Kuwata; R Shastry; H Cheng; Masaru Hoshino; Carl A Batt; Yuji Goto; H Roder
Structural and kinetic characterization of early folding events in beta-lactoglobulin.
Nature structural biology 2001;8(2):151-5.
2000: Masaru Hoshino; Yoshihisa Hagihara; Ichiro Nishii; Toshio Yamazaki; Hisao Kato; Yuji Goto
Identification of the phospholipid-binding site of human beta(2)-glycoprotein I domain V by heteronuclear magnetic resonance.
Journal of molecular biology 2000;304(5):927-39.
2000: K Sakai; Kazumasa Sakurai; M Sakai; Masaru Hoshino; Yuji Goto
Conformation and stability of thiol-modified bovine beta-lactoglobulin.
Protein science : a publication of the Protein Society 2000;9(9):1719-29.
2000: V Forge; Masaru Hoshino; K Kuwata; M Arai; K Kuwajima; Carl A Batt; Yuji Goto
Is folding of beta-lactoglobulin non-hierarchic? Intermediate with native-like beta-sheet and non-native alpha-helix.
Journal of molecular biology 2000;296(4):1039-51.
1999: K Kuwata; Masaru Hoshino; V Forge; Seiichi Era; Carl A Batt; Yuji Goto
Solution structure and dynamics of bovine beta-lactoglobulin A.
Protein science : a publication of the Protein Society 1999;8(11):2541-5.
1999: Ryujiroh Yamasaki; Masaru Hoshino; Tetsuichi Wazawa; Yoshiharu Ishii; Toshio Yanagida; Yasushi Kawata; Takashi Higurashi; K Sakai; J Nagai; Yuji Goto
Single molecular observation of the interaction of GroEL with substrate proteins.
Journal of molecular biology 1999;292(5):965-72.
1999: N Hirota-Nakaoka; Yuji Goto
Alcohol-induced denaturation of beta-lactoglobulin: a close correlation to the alcohol-induced alpha-helix formation of melittin.
Bioorganic & medicinal chemistry 1999;7(1):67-73.
1998: K Kuwata; Masaru Hoshino; Seiichi Era; Carl A Batt; Yuji Goto
alpha-->beta transition of beta-lactoglobulin as evidenced by heteronuclear NMR.
Journal of molecular biology 1998;283(4):731-9.
1998: N Ohkura; Yoshihisa Hagihara; T Yoshimura; Yuji Goto; Hisao Kato
Plasmin can reduce the function of human beta2 glycoprotein I by cleaving domain V into a nicked form.
Blood 1998;91(11):4173-9.
1998: N Hirota; K Mizuno; Yuji Goto
Group additive contributions to the alcohol-induced alpha-helix formation of melittin: implication for the mechanism of the alcohol effects on proteins.
Journal of molecular biology 1998;275(2):365-78.
1998: Yoshihisa Hagihara; Masaru Hoshino; Daizo Hamada; M Kataoka; Yuji Goto
Chain-like conformation of heat-denatured ribonuclease A and cytochrome c as evidenced by solution X-ray scattering.
Folding & design 1998;3(3):195-201.
1997: Masaru Hoshino; Yoshihisa Hagihara; Daizo Hamada; M Kataoka; Yuji Goto
Trifluoroethanol-induced conformational transition of hen egg-white lysozyme studied by small-angle X-ray scattering.
FEBS letters 1997;416(1):72-6.
1997: Masaru Hoshino; Noboru Yumoto; S Yoshikawa; Yuji Goto
Design and characterization of the anion-sensitive coiled-coil peptide.
Protein science : a publication of the Protein Society 1997;6(7):1396-404.
1997: Daizo Hamada; Yuji Goto
The equilibrium intermediate of beta-lactoglobulin with non-native alpha-helical structure.
Journal of molecular biology 1997;269(4):479-87.
1997: Junzo Tanaka; T Nagai; H Arai; Koji Inui; H Yamanouchi; Yuji Goto; I Nonaka; Shintaro Okada
Treatment of mitochondrial encephalomyopathy with a combination of cytochrome C and vitamins B1 and B2.
Brain & development 1997;19(4):262-7.
1997: M Kataoka; K Kuwajima; F Tokunaga; Yuji Goto
Structural characterization of the molten globule of alpha-lactalbumin by solution X-ray scattering.
Protein science : a publication of the Protein Society 1997;6(2):422-30.
1997: N Hirota; K Mizuno; Yuji Goto
Cooperative alpha-helix formation of beta-lactoglobulin and melittin induced by hexafluoroisopropanol.
Protein science : a publication of the Protein Society 1997;6(2):416-21.
1997: Yoshihisa Hagihara; K Enjyoji; Takeshi Omasa; Yoshio Katakura; KI Suga; M Igarashi; E Matsuura; Hisao Kato; T Yoshimura; Yuji Goto
Structure and function of the recombinant fifth domain of human beta 2-glycoprotein I: effects of specific cleavage between Lys77 and Thr78.
Journal of biochemistry 1997;121(1):128-37.
1996: Masaru Hoshino; Yasushi Kawata; Yuji Goto
Interaction of GroEL with conformational states of horse cytochrome c.
Journal of molecular biology 1996;262(4):575-87.
1996: Daizo Hamada; S Segawa; Yuji Goto
Non-native alpha-helical intermediate in the refolding of beta-lactoglobulin, a predominantly beta-sheet protein.
Nature structural biology 1996;3(10):868-73.
1996: Daizo Hamada; Y Kuroda; M Kataoka; S Aimoto; T Yoshimura; Yuji Goto
Role of heme axial ligands in the conformational stability of the native and molten globule states of horse cytochrome c.
Journal of molecular biology 1996;256(1):172-86.
1996: M Kataoka; Yuji Goto
X-ray solution scattering studies of protein folding.
Folding & design 1996;1(5):R107-14.
1995: Daizo Hamada; Y Kuroda; T Tanaka; Yuji Goto
High helical propensity of the peptide fragments derived from beta-lactoglobulin, a predominantly beta-sheet protein.
Journal of molecular biology 1995;254(4):737-46.
1995: I Nishii; M Kataoka; Yuji Goto
Thermodynamic stability of the molten globule states of apomyoglobin.
Journal of molecular biology 1995;250(2):223-38.
1995: M Kataoka; I Nishii; T Fujisawa; T Ueki; Fumio Tokunaga; Yuji Goto
Structural characterization of the molten globule and native states of apomyoglobin by solution X-ray scattering.
Journal of molecular biology 1995;249(1):215-28.
1995: K Shiraki; K Nishikawa; Yuji Goto
Trifluoroethanol-induced stabilization of the alpha-helical structure of beta-lactoglobulin: implication for non-hierarchical protein folding.
Journal of molecular biology 1995;245(2):180-94.
1994: Daizo Hamada; S Kidokoro; H Fukada; K Takahashi; Yuji Goto
Salt-induced formation of the molten globule state of cytochrome c studied by isothermal titration calorimetry.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10325-9.
1994: Masaru Hoshino; Yuji Goto
Perchlorate-induced formation of the alpha-helical structure of mastoparan.
Journal of biochemistry 1994;116(4):910-5.
1994: Yoshihisa Hagihara; M Oobatake; Yuji Goto
Thermal unfolding of tetrameric melittin: comparison with the molten globule state of cytochrome c.
Protein science : a publication of the Protein Society 1994;3(9):1418-29.
1994: I Nishii; M Kataoka; Fumio Tokunaga; Yuji Goto
Cold denaturation of the molten globule states of apomyoglobin and a profile for protein folding.
Biochemistry 1994;33(16):4903-9.
1994: Yoshihisa Hagihara; Y Tan; Yuji Goto
Comparison of the conformational stability of the molten globule and native states of horse cytochrome c. Effects of acetylation, heat, urea and guanidine-hydrochloride.
Journal of molecular biology 1994;237(3):336-48.
1994: Yuji Goto; Anthony L Fink
Acid-induced folding of heme proteins.
Methods in enzymology 1994;232():3-15.
1993: Yuji Goto; Yoshihisa Hagihara; Daizo Hamada; Masaru Hoshino; I Nishii
Acid-induced unfolding and refolding transitions of cytochrome c: a three-state mechanism in H2O and D2O.
Biochemistry 1993;32(44):11878-85.
1993: Daizo Hamada; Masaru Hoshino; M Kataoka; Anthony L Fink; Yuji Goto
Intermediate conformational states of apocytochrome c.
Biochemistry 1993;32(39):10351-8.
1993: Yoshihisa Hagihara; S Aimoto; Anthony L Fink; Yuji Goto
Guanidine hydrochloride-induced folding of proteins.
Journal of molecular biology 1993;231(2):180-4.
1993: M Kataoka; Yoshihisa Hagihara; K Mihara; Yuji Goto
Molten globule of cytochrome c studied by small angle X-ray scattering.
Journal of molecular biology 1993;229(3):591-6.
1993: Yuji Goto; E Kogure; T Takagi; S Aimoto; T Aoba
Molecular conformation of porcine amelogenin in solution: three folding units at the N-terminal, central, and C-terminal regions.
Journal of biochemistry 1993;113(1):55-60.
1992: Yoshihisa Hagihara; M Kataoka; S Aimoto; Yuji Goto
Charge repulsion in the conformational stability of melittin.
Biochemistry 1992;31(47):11908-14.
1992: Yuji Goto; Yoshihisa Hagihara
Mechanism of the conformational transition of melittin.
Biochemistry 1992;31(3):732-8.
1991: Yuji Goto; S Nishikiori
Role of electrostatic repulsion in the acidic molten globule of cytochrome c.
Journal of molecular biology 1991;222(3):679-86.
1991: Yuji Goto; N Okamura; S Aimoto
ATP-induced conformational transition of denatured proteins.
Journal of biochemistry 1991;109(5):746-50.
1991: Yuji Goto; S Aimoto
Anion and pH-dependent conformational transition of an amphiphilic polypeptide.
Journal of molecular biology 1991;218(2):387-96.
1990: Yuji Goto; Anthony L Fink
Phase diagram for acidic conformational states of apomyoglobin.
Journal of molecular biology 1990;214(4):803-5.
1990: Yuji Goto; N Takahashi; Anthony L Fink
Mechanism of acid-induced folding of proteins.
Biochemistry 1990;29(14):3480-8.
1988: Yuji Goto; N Ichimura; K Hamaguchi
Effects of ammonium sulfate on the unfolding and refolding of the variable and constant fragments of an immunoglobulin light chain.
Biochemistry 1988;27(5):1670-7.
1988: Yasushi Kawata; Yuji Goto; K Hamaguchi; F Hayashi; Y Kobayashi; Yoshimasa Kyogoku
Hydrogen-exchange kinetics of the indole NH proton of the buried tryptophan in the constant fragment of the immunoglobulin light chain.
Biochemistry 1988;27(1):346-50.
1987: M Tsunenaga; Yuji Goto; Yasushi Kawata; K Hamaguchi
Unfolding and refolding of a type kappa immunoglobulin light chain and its variable and constant fragments.
Biochemistry 1987;26(19):6044-51.
1987: H Kikuchi; Yuji Goto; K Hamaguchi; S Ito; M Yamamoto; Y Nishijima
Fluorescence of the tryptophyl residues of the constant fragment of the immunoglobulin light chain.
Journal of biochemistry 1987;102(3):651-6.