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Vicente Gotor
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29
Ferrero, Miguel
27
Fernández, Susana
11
Alfonso, Ignacio
10
Gotor-Fernández, Vicente
9
Lavandera, Iván
7
Sanghvi, Yogesh
6
Verstuyf, Annemieke
4
Verlinden, Lieve
4
González-Sabín, Javier
4
Rebolledo, Francisca
4
García, Javier
3
Dehli, Juan
3
García-España, Enrique
3
Armesto, Nuria
3
Bouillon, Roger
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All Publications
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2009: Sánchez-Abella Laura; Fernández Susana; Verstuyf Annemieke; Verlinden Lieve; Gotor Vicente; Ferrero Miguel
Synthesis, conformational analysis, and biological evaluation of 19-nor-vitamin D3 analogues with A-ring modifications.
Journal of medicinal chemistry 2009;52(19):6158-62.
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2009: Mangas-Sánchez Juan; Rodríguez-Mata María; Busto Eduardo; Gotor-Fernández Vicente; Gotor Vicente
Chemoenzymatic synthesis of rivastigmine based on lipase-catalyzed processes.
The Journal of organic chemistry 2009;74(15):5304-10.
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2009: García-Urdiales Eduardo; Ríos-Lombardía Nicolás; Mangas-Sánchez Juan; Gotor-Fernández Vicente; Gotor Vicente
Influence of the nucleophile on the Candida antarctica lipase B-catalysed resolution of a chiral acyl donor.
Chembiochem : a European journal of chemical biology 2009;10(11):1830-8.
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2009: González-Sabín Javier; Rebolledo Francisca; Gotor Vicente
trans-cyclopentane-1,2-diamine: the second youth of the forgotten diamine.
Chemical Society reviews 2009;38(7):1916-25.
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2009: Díaz-Rodríguez Alba; Sanghvi Yogesh S; Fernández Susana; Schinazi Raymond F; Theodorakis Emmanuel A; Ferrero Miguel; Gotor Vicente
Synthesis and anti-HIV activity of conformationally restricted bicyclic hexahydroisobenzofuran nucleoside analogs.
Organic & biomolecular chemistry 2009;7(7):1415-23.
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2009: Ríos-Lombardía Nicolás; Busto Eduardo; García-Urdiales Eduardo; Gotor-Fernández Vicente; Gotor Vicente
Enzymatic desymmetrization of prochiral 2-substituted-1,3-diamines: preparation of valuable nitrogenated compounds.
The Journal of organic chemistry 2009;74(6):2571-4.
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2009: Bisogno Fabricio R; Lavandera Iván; Kroutil Wolfgang; Gotor Vicente
Tandem concurrent processes: one-pot single-catalyst biohydrogen transfer for the simultaneous preparation of enantiopure secondary alcohols.
The Journal of organic chemistry 2009;74(4):1730-2.
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2009: González-Alvarez Almudena; Alfonso Ignacio; Cano Juan; Díaz Pilar; Gotor Vicente; Gotor-Fernández Vicente; García-España Enrique; García-Granda Santiago; Jiménez Hermas R; Lloret Francesc
A ferromagnetic [Cu3(OH)2]4+ cluster formed inside a tritopic nonaazapyridinophane: crystal structure and solution studies.
Angewandte Chemie (International ed. in English) 2009;48(33):6055-8.
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2008: Sánchez-Abella Laura; Fernández Susana; Verstuyf Annemieke; Verlinden Lieve; Gotor Vicente; Ferrero Miguel
Synthesis and biological activity of previtamin D(3) analogues with A-ring modifications.
Bioorganic & medicinal chemistry 2008;16(24):10244-50.
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2008: Morán-Ramallal Roberto; Liz Ramón; Gotor Vicente
Regioselective and stereospecific synthesis of enantiopure 1,3-oxazolidin-2-ones by intramolecular ring opening of 2-(Boc-aminomethyl)aziridines. Preparation of the antibiotic linezolid.
Organic letters 2008;10(10):1935-8.
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2008: González-Alvarez Almudena; Alfonso Ignacio; Díaz Pilar; García-España Enrique; Gotor-Fernández Vicente; Gotor Vicente
A simple helical macrocyclic polyazapyridinophane as a stereoselective receptor of biologically important dicarboxylates under physiological conditions.
The Journal of organic chemistry 2008;73(2):374-82.
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2008: Díaz-Rodríguez Alba; Fernández Susana; Sanghvi Yogesh S; Theodorakis Emmanuel A; Gotor Vicente; Ferrero Miguel
Synthesis of 2',3'-cyclohexene bicyclic nucleoside analogues as antiviral compounds.
Nucleic acids symposium series (2004) 2008;(52):99-100.
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2007: Busto Eduardo; Gotor-Fernández Vicente; Montejo-Bernardo Jose; Gárcía-Granda Santiago; Gotor Vicente
First desymmetrization of 1,3-propanediamine derivatives in organic solvent. Development of a new route for the preparation of optically active amines.
Organic letters 2007;9(21):4203-6.
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2007: Sánchez-Abella Laura; Fernández Susana; Verstuyf Annemieke; Verlinden Lieve; Ferrero Miguel; Gotor Vicente
Synthesis and biological evaluation of new 6-s-cis locked 1,2,25-trihydroxyprevitamin D3 analogues.
Bioorganic & medicinal chemistry 2007;15(12):4193-202.
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2007: Peña Carmen; Alfonso Ignacio; Tooth Blake; Voelcker Nicolas H; Gotor Vicente
Synthesis and stereoselective DNA binding abilities of new optically active open-chain polyamines.
The Journal of organic chemistry 2007;72(6):1924-30.
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2007: González-Sabín Javier; Gotor Vicente; Rebolledo Francisca
A biocatalytic approach to synthesizing optically active orthogonally protected trans-cyclopentane-1,2-diamine derivatives.
The Journal of organic chemistry 2007;72(4):1309-14.
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2007: Moran-Ramallal Roberto; Liz Ramón; Gotor Vicente
Bacterial preparation of enantiopure unactivated aziridine-2-carboxamides and their transformation into enantiopure nonnatural amino acids and vic-diamines.
Organic letters 2007;9(3):521-4.
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2006: García Javier; Díaz-Rodríguez Alba; Fernandez Susana; Sanghvi Yogesh S; Ferrero Miguel; Gotor Vicente
New concept for the separation of an anomeric mixture of alpha/beta-D-nucleosides through regioselective enzymatic acylation or hydrolysis processes.
The Journal of organic chemistry 2006;71(26):9765-71.
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2006: Oves Daniel; Fernández Susana; Verlinden Lieve; Bouillon Roger; Verstuyf Annemieke; Ferrero Miguel; Gotor Vicente
Novel A-ring homodimeric C-3-carbamate analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation.
Bioorganic & medicinal chemistry 2006;14(22):7512-9.
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2006: González-Sabín Javier; Gotor Vicente; Rebolledo Francisca
Optically active trans-2-aminocyclopentanols: chemoenzymatic preparation and application as chiral ligands.
Biotechnology journal 2006;1(7-8):835-41.
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2006: Sánchez-Abella Laura; Fernández Susana; Armesto Nuria; Ferrero Miguel; Gotor Vicente
Novel and efficient syntheses of (-)-methyl 4-epi-shikimate and 4,5-epoxy-quinic and -shikimic acid derivatives as key precursors to prepare new analogues.
The Journal of organic chemistry 2006;71(14):5396-9.
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2006: González-Alvarez Almudena; Alfonso Ignacio; Gotor Vicente
Highly diastereoselective amplification from a dynamic combinatorial library of macrocyclic oligoimines.
Chemical communications (Cambridge, England) 2006;(21):2224-6.
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2006: Lavandera Iván; Fernández Susana; Magdalena Julia; Ferrero Miguel; Grewal Harjap; Savile Christopher K; Kazlauskas Romas J; Gotor Vicente
Remote interactions explain the unusual regioselectivity of lipase from Pseudomonas cepacia toward the secondary hydroxyl of 2'-deoxynucleosides.
Chembiochem : a European journal of chemical biology 2006;7(4):693-8.
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2006: González-Alvarez Almudena; Alfonso Ignacio; Díaz Pilar; García-España Enrique; Gotor Vicente
A highly enantioselective abiotic receptor for malate dianion in aqueous solution.
Chemical communications (Cambridge, England) 2006;(11):1227-9.
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2006: Oves Daniel; Fernández Susana; Ferrero Miguel; Bouillon Roger; Verstuyf Annemieke; Gotor Vicente
Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1alpha,25-dihydroxyvitamin D3 analogues.
Bioorganic & medicinal chemistry 2006;14(4):928-37.
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2006: Busto Eduardo; Gotor-Fernández Vicente; Gotor Vicente
Kinetic resolution of 4-chloro-2-(1-hydroxyalkyl)pyridines using Pseudomonas cepacia lipase.
Nature protocols 2006;1(4):2061-7.
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2005: Lavandera Iván; Fernández Susana; Magdalena Julia; Ferrero Miguel; Kazlauskas Romas J; Gotor Vicente
An inverse substrate orientation for the regioselective acylation of 3',5'-diaminonucleosides catalyzed by Candida antarctica lipase B?
Chembiochem : a European journal of chemical biology 2005;6(8):1381-90.
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2005: Lavandera Iván; García Javier; Fernández Susana; Ferrero Miguel; Gotor Vicente; Sanghvi Yogesh S
Enzymatic regioselective levulinylation of 2'-deoxyribonucleosides and 2'-o-methylribonucleosides.
Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2005;Chapter 2():Unit 2.11.
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2005: García-Urdiales Eduardo; Alfonso Ignacio; Gotor Vicente
Enantioselective enzymatic desymmetrizations in organic synthesis.
Chemical reviews 2005;105(1):313-54.
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2004: González-Sabín Javier; Gotor Vicente; Rebolledo Francisca
Chemoenzymatic preparation of optically active trans-cyclohexane-1,2-diamine derivatives: an efficient synthesis of the analgesic U-(-)-50,488.
Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(22):5788-94.
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2004: García Javier; Fernández Susana; Ferrero Miguel; Sanghvi Yogesh S; Gotor Vicente
Regioselective enzymatic acylation of beta-L-2'-deoxynucleosides: application in resolution of beta-D/L-2'-deoxynucleosides.
Organic letters 2004;6(21):3759-62.
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2004: Gotor-Fernández Vicente; Fernández Susana; Ferrero Miguel; Gotor Vicente; Bouillon Roger; Verstuyf Annemieke
Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1alpha,25-dihydroxyvitamin D3.
Bioorganic & medicinal chemistry 2004;12(20):5443-51.
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2004: Levy Laura M; Lavandera Iván; Gotor Vicente
Is the ring conformation the most critical parameter in lipase-catalysed acylation of cycloalkanols?
Organic & biomolecular chemistry 2004;2(18):2572-7.
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2004: Torre Oliver; Alfonso Ignacio; Gotor Vicente
Lipase catalysed Michael addition of secondary amines to acrylonitrile.
Chemical communications (Cambridge, England) 2004;(15):1724-5.
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2004: López-García Mónica; Alfonso Ignacio; Gotor Vicente
Highly efficient biocatalytic resolution of cis- and trans-3-aminoindan-1-ol: syntheses of enantiopure orthogonally protected cis- and trans-indane-1,3-diamine.
Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(12):3006-14.
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2004: Alfonso Ignacio; Gotor Vicente
Biocatalytic and biomimetic aminolysis reactions: useful tools for selective transformations on polyfunctional substrates.
Chemical Society reviews 2004;33(4):201-9.
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2004: Levy Laura M; Gotor Vicente
Synthesis and enzymatic kinetic resolution of alpha,alpha-disubstituted cyclic hydroxy nitriles.
The Journal of organic chemistry 2004;69(7):2601-2.
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2004: Lavandera Iván; Fernández Susana; Ferrero Miguel; Gotor Vicente
First regioselective enzymatic alkoxycarbonylation of primary amines. Synthesis of novel 5'- and 3'-carbamates of pyrimidine 3',5'-diaminonucleoside derivatives including BVDU analogues.
The Journal of organic chemistry 2004;69(5):1748-51.
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2004: Taourirte M; Mohamed L Ait; Rochdi A; Vasseur J J; Fernández S; Ferrero M; Gotor V; Pannecouque C; De Clercq E; Lazrek H B
Chemoenzymatic syntheses of homo- and heterodimers of AZT and d4T, and evaluation of their anti-HIV activity.
Nucleosides, nucleotides & nucleic acids 2004;23(4):701-14.
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2003: Lavandera Iván; Fernández Susana; Ferrero Miguel; De Clercq Erik; Gotor Vicente
Synthesis, protonation behavior, conformational analysis, and regioselective enzymatic acylation of the novel diamino analogue of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
Nucleosides, nucleotides & nucleic acids 2003;22(10):1939-52.
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2003: Armesto Nuria; Ferrero Miguel; Fernández Susana; Gotor Vicente
Novel enzymatic synthesis of 4-O-cinnamoyl quinic and shikimic acid derivatives.
The Journal of organic chemistry 2003;68(14):5784-7.
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2003: García Javier; Fernández Susana; Ferrero Miguel; Sanghvi Yogesh S; Gotor Vicente
Direct regioselective enzymatic acylation of nucleosides: building-blocks for the solution phase synthesis of oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1455-7.
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2003: Lavandera Iván; Fernández Susana; Ferrero Miguel; De Clercq Erik; Gotor Vicente
Synthesis and antiviral activity assay of novel (E)-3',5'-diamino-5-(2-bromovinyl)-2',3',5'-trideoxyuridine.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):833-6.
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2003: de Gonzalo Gonzalo; Brieva Rosario; Sánchez Víctor M; Bayod Miguel; Gotor Vicente
Anhydrides as acylating agents in the enzymatic resolution of an intermediate of (-)-Paroxetine.
The Journal of organic chemistry 2003;68(8):3333-6.
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2003: Oves Daniel; Ferrero Miguel; Fernández Susana; Gotor Vicente
Efficient synthesis of novel 1alpha-amino and 3beta-amino analogues of 1alpha,25-dihydroxyvitamin d(3).
The Journal of organic chemistry 2003;68(3):1154-7.
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2003: López-García Mónica; Alfonso Igancio; Gotor Vicente
Synthesis of (R)-3,4-diaminobutanoic acid by desymmetrization of dimethyl 3-(benzylamino)glutarate through enzymatic ammonolysis.
The Journal of organic chemistry 2003;68(2):648-51.
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2002: Dehli Juan R; Gotor Vicente
Parallel kinetic resolution of racemic mixtures: a new strategy for the preparation of enantiopure compounds?
Chemical Society reviews 2002;31(6):365-70.
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2002: Luna Amparo; Alfonso Ignacio; Gotor Vicente
Biocatalytic approaches toward the synthesis of both enantiomers of trans-cyclopentane-1,2-diamine.
Organic letters 2002;4(21):3627-9.
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2002: Dehli Juan R; Gotor Vicente
Dynamic kinetic resolution of 2-oxocycloalkanecarbonitriles: chemoenzymatic syntheses of optically active yclic beta- and gamma-amino alcohols.
The Journal of organic chemistry 2002;67(19):6816-9.
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2002: Armesto Nuria; Ferrero Miguel; Fernández Susana; Gotor Vicente
Regioselective enzymatic acylation of methyl shikimate. Influence of acyl chain length and solvent polarity on enzyme specificity.
The Journal of organic chemistry 2002;67(14):4978-81.
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2002: Gotor Vicente
Lipases and (R)-oxynitrilases: useful tools in organic synthesis.
Journal of biotechnology 2002;96(1):35-42.
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2002: García Javier; Fernández Susana; Ferrero Miguel; Sanghvi Yogesh S; Gotor Vicente
Building blocks for the solution phase synthesis of oligonucleotides: regioselective hydrolysis of 3',5'-Di-O-levulinylnucleosides using an enzymatic approach.
The Journal of organic chemistry 2002;67(13):4513-9.
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2002: Dehli Juan R; Gotor Vicente
Preparation of enantiopure ketones and alcohols containing a quaternary stereocenter through parallel kinetic resolution of beta-keto nitriles.
The Journal of organic chemistry 2002;67(5):1716-8.
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2002: Gotor-Fernández Vicente; Ferrero Miguel; Fernández Susana; Gotor Vicente
Synthesis of monoacyl A-ring precursors of 1alpha,25-dihydroxyvitamin D3 through selective enzymatic hydrolysis.
The Journal of organic chemistry 2002;67(4):1266-70.
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2002: Magdalena Julia; Fernández Susana; Ferrero Miguel; Gotor Vicente
Difficulties in the deprotection of 1,2-ketals in nucleosides containing alkylidencarbazoyl groups.
Nucleosides, nucleotides & nucleic acids 2002;21(1):55-64.
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2001: de Gonzalo G; Brieva R; Sánchez V M; Bayod M; Gotor V
Enzymatic resolution of trans-4-(4'-fluorophenyl)-3-hydroxymethylpiperidines, key intermediates in the synthesis of (-)-Paroxetine.
The Journal of organic chemistry 2001;66(26):8947-53.
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2001: Díaz M; Gotor-Fernández V; Ferrero M; Fernández S; Gotor V
Cal-B-catalyzed alkoxycarbonylation of a-ring stereoisomeric synthons of 1alpha,25-dihydroxyvitamin D3 and 1alpha,25-dihydroxy-19-nor-previtamin D3: a comparative study. first regioselective chemoenzymatic synthesis of 19-nor-A-ring carbonates.
The Journal of organic chemistry 2001;66(12):4227-32.
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2001: Lavandera I; Fernández S; Ferrero M; Gotor V
First regioselective enzymatic acylation of amino groups applied to pyrimidine 3',5'-diaminonucleoside derivatives. Improved synthesis of pyrimidine 3',5'-diamino-2',3',5'-trideoxynucleosides.
The Journal of organic chemistry 2001;66(11):4079-82.
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2001: Taourirte M; Lazrek H B; Vasseur J J; Ferrero M; Fernandez S; Gotor V
Synthesis of new homo and heterodinucleosides containing the 2',3'-dideoxynucleosides AZT and D4T.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):959-62.
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2000: Díaz M; Ferrero M; Fernández S; Gotor V
6-s-cis locked analogues of the steroid hormone 1alpha, 25-dihydroxyvitamin D(3). Synthesis Of novel A-ring stereoisomeric 1, 25-dihydroxy-3-epi-19-nor-previtamin D(3) derivatives.
The Journal of organic chemistry 2000;65(18):5647-52.
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1999: Gotor V
Non-conventional hydrolase chemistry: amide and carbamate bond formation catalyzed by lipases.
Bioorganic & medicinal chemistry 1999;7(10):2189-97.
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1998: García-Alles L F; Gotor V
Lipase-catalyzed transesterification in organic media: solvent effects on equilibrium and individual rate constants.
Biotechnology and bioengineering 1998;59(6):684-94.
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