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Marie-José Goumans

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Asja T Moerkamp; Agnieszka Paca; Marie-José Goumans; Boudewijn P T Kruithof; Tilo Kunath; Marianna Kruithof-de Julio
Extraembryonic Endoderm cells as a model of endoderm development.
Charlotte Anderberg; Helen M Arthur; Oriol Casanovas; Ross Cordiner; Eliane Cortez; Sara I Cunha; Marcela Franco; Jonas Fuxe; Marie-José Goumans; Bengt R Johansson; Jill R Johnson; Marta Páez-Ribes; Evangelia Pardali; Peter ten Dijke; Zhenhua Zhai; Kristian Pietras
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination.
Simone Post; Benno J Rensing; Alexandra J van den Broek; Marie-José Goumans; Gerard Pasterkamp; Pieter A Doevendans
Reduced CD26 expression is associated with improved cardiac function after acute myocardial infarction: insights from the REPERATOR study.

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2013: Asja T Moerkamp; Agnieszka Paca; Marie-José Goumans; Boudewijn P T Kruithof; Tilo Kunath; Marianna Kruithof-de Julio
Extraembryonic Endoderm cells as a model of endoderm development.
Development, growth & differentiation 2013;55(3):301-8.
2013: Charlotte Anderberg; Helen M Arthur; Oriol Casanovas; Ross Cordiner; Eliane Cortez; Sara I Cunha; Marcela Franco; Jonas Fuxe; Marie-José Goumans; Bengt R Johansson; Jill R Johnson; Marta Páez-Ribes; Evangelia Pardali; Peter ten Dijke; Zhenhua Zhai; Kristian Pietras
Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination.
The Journal of experimental medicine 2013;210(3):563-79.
2012: Simone Post; Benno J Rensing; Alexandra J van den Broek; Marie-José Goumans; Gerard Pasterkamp; Pieter A Doevendans
Reduced CD26 expression is associated with improved cardiac function after acute myocardial infarction: insights from the REPERATOR study.
Journal of molecular and cellular cardiology 2012;53(6):899-905.
2012: Simone Post; Benno J Rensing; Pieter R Stella; Ben J van den Branden; Hendrik W van Es; Thierry X Wildbergh; Frank D Eefting; Marie-José Goumans; Martijn C Post; Pieter A Doevendans
Early statin treatment prior to primary PCI for acute myocardial infarction: REPERATOR, a randomized placebo-controlled pilot trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2012;80(5):756-65.
2012: Noortje A M Bax; Carlijn V C Bouten; Marie-José Goumans; Bhakti Shah; Mieke H van Marion; Daisy W J van der Schaft
Matrix production and remodeling capacity of cardiomyocyte progenitor cells during in vitro differentiation.
Journal of molecular and cellular cardiology 2012;53(4):497-508.
2012: Leonard Seghers; Peter Ten Dijke; Margreet R De Vries; Marie-José Goumans; Beerend P Hierck; Imo E Hoefer; Evangelia Pardali; Paul H A Quax
Shear induced collateral artery growth modulated by endoglin but not by ALK1.
Journal of cellular and molecular medicine 2012;16(10):2440-50.
2012: Patrick van Vliet; Pieter A Doevendans; Marie-José Goumans; Joost P G Sluijter
Human cardiomyocyte progenitor cells: a short history of nearly everything.
Journal of cellular and molecular medicine 2012;16(8):1669-73.
2012: Boudewijn P T Kruithof; Asja T Moerkamp; Sjoerd N Duim; Marie-José Goumans
TGFβ and BMP signaling in cardiac cushion formation: lessons from mice and chicken.
Differentiation; research in biological diversity 2012;84(1):89-102.
2012: Melina C den Haan; Pieter A Doevendans; Willem E Fibbe; Adriana C Gittenberger-De Groot; Marie-José Goumans; Robert W Grauss; Daniël A Pijnappels; Martin J Schalij; Anke M Smits; Paul Steendijk; Arnoud van der Laarse; John van Tuyn; Elizabeth M Winter; Antoine A F de Vries; Douwe E Atsma
Cardiomyogenic differentiation-independent improvement of cardiac function by human cardiomyocyte progenitor cell injection in ischaemic mouse hearts.
Journal of cellular and molecular medicine 2012;16(7):1508-21.
2012: Arti A Ramkisoensing; Martin J Schalij; Jim Swildens; Antoine A F de Vries; Willem E Fibbe; Marie-José Goumans; Daniël A Pijnappels; Douwe E Atsma
Gap junctional coupling with cardiomyocytes is necessary but not sufficient for cardiomyogenic differentiation of cocultured human mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2012;30(6):1236-45.
2012: Laurens van Meeteren; Corrado Gallo Stampino; Midory Thorikay; Simon Bergqvist; Marie-José Goumans; Dana Hu-Lowe; Evangelia Pardali; Peter ten Dijke
Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting.
The Journal of biological chemistry 2012;287(22):18551-61.
2012: Alain van Mil; Pieter A Doevendans; Marie-José Goumans; Sebastian Grundmann; Sridevi Jaksani; Zhiyong Lei; Martinus I Oerlemans; Joost P G Sluijter
MicroRNA-214 inhibits angiogenesis by targeting Quaking and reducing angiogenic growth factor release.
Cardiovascular research 2012;93(4):655-65.
2012: Peter ten Dijke; Robert E Poelmann; Anastasia D Egorova; Marie-José Goumans; Beerend P Hierck
TGF-β signaling in endothelial-to-mesenchymal transition: the role of shear stress and primary cilia.
Science signaling 2012;5(212):pt2.
2012: Anke M Smits; Angelique A van Oorschot; Marie-José Goumans
Isolation and differentiation of human cardiomyocyte progenitor cells into cardiomyocytes.
Methods in molecular biology (Clifton, N.J.) 2012;879():339-49.
2011: Angelique A M van Oorschot; Pieter A Doevendans; Evangelia Pardali; Anke M Smits; Marie-José Goumans
Low oxygen tension positively influences cardiomyocyte progenitor cell function.
Journal of cellular and molecular medicine 2011;15(12):2723-34.
2011: Noortje A M Bax; Jerry Braun; Antoine A F de Vries; Marie-José Goumans; Saskia Maas; Daniël A Pijnappels; Martin J Schalij; Angelique A M van Oorschot; John van Tuyn; Elizabeth M Winter; Douwe E Atsma; Adriana C Gittenberger-De Groot
Epithelial-to-mesenchymal transformation alters electrical conductivity of human epicardial cells.
Journal of cellular and molecular medicine 2011;15(12):2675-83.
2011: Joost P Sluijter; Pieter A Doevendans; Marie-José Goumans
Letter by Sluijter et al regarding article, "Human cardiac stem cell differentiation is regulated by a mircrine mechanism".
Circulation 2011;124(17):e456; author's reply e457.
2011: Valeria V Orlova; Marie-José Goumans; Zhen Liu; Peter ten Dijke
Controlling angiogenesis by two unique TGF-β type I receptor signaling pathways.
Histology and histopathology 2011;26(9):1219-30.
2011: Pieter T Bot; Onno de Boer; Dominique de Kleijn; Jean-Paul de Vries; Marie-José Goumans; Sebastian Grundmann; Frans Moll; Gerard Pasterkamp; Jan J Piek; Allard C van der Wal; Niels van Royen; Alex van Soest; Imo E Hoefer
Forkhead box protein P1 as a downstream target of transforming growth factor-β induces collagen synthesis and correlates with a more stable plaque phenotype.
Atherosclerosis 2011;218(1):33-43.
2011: Noortje A M Bax; Jerry Braun; Antoine A F de Vries; Adriana C Gittenberger-de Groot; Saskia Maas; Angelique A M van Oorschot; John van Tuyn; Marie-José Goumans
In vitro epithelial-to-mesenchymal transformation in human adult epicardial cells is regulated by TGFβ-signaling and WT1.
Basic research in cardiology 2011;106(5):829-47.
2011: Anastasia D Egorova; Adriana C Gittenberger-De Groot; Marie-José Goumans; Christian Poelma; Robert E Poelmann; Peter ten Dijke; Simone van de Pas; Kim Van der Heiden; Peter Vennemann; Marco C DeRuiter; Beerend P Hierck
Tgfβ/Alk5 signaling is required for shear stress induced klf2 expression in embryonic endothelial cells.
Developmental dynamics : an official publication of the American Association of Anatomists 2011;240(7):1670-80.
2011: Jia Liu; Corina H G Metz; Pieter A Doevendans; Ling Gao; Marie-José Goumans; Alain van Mil; Krijn Vrijsen; Jiajun Zhao; Joost P G Sluijter
MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1.
Journal of cellular and molecular medicine 2011;15(7):1474-82.
2011: Leo Timmers; Sai-Kiang Lim; Imo E Hoefer; Fatih Arslan; Ruenn Chai Lai; Angelique A M van Oorschot; Marie-José Goumans; Chaylendra Strijder; Sui Kwan Sze; Andree Choo; Jan J Piek; Pieter A Doevendans; Gerard Pasterkamp; Dominique P V de Kleijn
Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction.
Stem cell research 2011;6(3):206-14.
2011: Anastasia D Egorova; Padmini P S J Khedoe; Marie-José Goumans; Bradley K Yoder; Surya M Nauli; Peter ten Dijke; Robert E Poelmann; Beerend P Hierck
Lack of primary cilia primes shear-induced endothelial-to-mesenchymal transition.
Circulation research 2011;108(9):1093-101.
2011: Bernard C te Boekhorst; Sandra M Bovens; Willem E Hellings; Petra H van der Kraak; Kees W van de Kolk; Aryan Vink; Frans L Moll; Matthijs F M van Oosterhout; Jean-Paul P M de Vries; Pieter A Doevendans; Marie-José Goumans; Dominique P V de Kleijn; Cees J A van Echteld; Gerard Pasterkamp; Joost P G Sluijter
Molecular MRI of murine atherosclerotic plaque targeting NGAL: a protein associated with unstable human plaque characteristics.
Cardiovascular research 2011;89(3):680-8.
2011: Arti A Ramkisoensing; Martin J Schalij; Sicco Scherjon; Cindy I Schutte; Jim Swildens; Antoine A F de Vries; Marie-José Goumans; Christine L Mummery; Passier Robert; Daniël A Pijnappels; Saïd F A Askar; Douwe E Atsma
Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterparts.
PloS one 2011;6(9):e24164.
2010: Simone Post; Marie-José Goumans; Pieter A Doevendans
Peripheral blood derived cell trafficking for cardiac regeneration.
Current stem cell research & therapy 2010;5(4):303-13.
2010: Evangelia Pardali; Marie-José Goumans; Peter ten Dijke
Signaling by members of the TGF-beta family in vascular morphogenesis and disease.
Trends in cell biology 2010;20(9):556-67.
2010: Pieter T Bot; Gerard Pasterkamp; Marie-José Goumans; Chaylendra Strijder; Frans L Moll; Jean-Paul de Vries; Steven T Pals; Dominique P V de Kleijn; Jan J Piek; Imo E Hoefer
Hyaluronic acid metabolism is increased in unstable plaques.
European journal of clinical investigation 2010;40(9):818-27.
2010: Martinus I F J Oerlemans; Marie-José Goumans; Ben van Middelaar; Hans Clevers; Pieter A Doevendans; Joost P G Sluijter
Active Wnt signaling in response to cardiac injury.
Basic research in cardiology 2010;105(5):631-41.
2010: A M Smits; A A Ramkisoensing; Douwe E Atsma; Marie-José Goumans
Young at heart. An update on cardiac regeneration.
Minerva medica 2010;101(4):255-70.
2010: Noortje A M Bax; Steven B Bleyl; Radiosa Gallini; Lambertus J Wisse; Jennifer Hunter; Angelique A M Van Oorschot; Edris A F Mahtab; Heleen Lie-Venema; Marie-José Goumans; Christer Betsholtz; Adriana C Gittenberger-De Groot
Cardiac malformations in Pdgfralpha mutant embryos are associated with increased expression of WT1 and Nkx2.5 in the second heart field.
Developmental dynamics : an official publication of the American Association of Anatomists 2010;239(8):2307-17.
2010: A A M Van Oorschot; A M Smits; Marie-José Goumans
Stem cells: the building blocks to repair the injured heart.
Panminerva medica 2010;52(2):97-110.
2010: Patrick van Vliet; Teun P de Boer; Marcel A G van der Heyden; Mazen K El Tamer; Joost P G Sluijter; Pieter A Doevendans; Marie-José Goumans
Hyperpolarization induces differentiation in human cardiomyocyte progenitor cells.
Stem cell reviews 2010;6(2):178-85.
2010: Maarten van Dinther; Nils Visser; David de Gorter; Joyce Doorn; Marie-José Goumans; Jan de Boer; Peter ten Dijke
ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(6):1208-15.
2010: Patrick van Vliet; Anke M Smits; Teun P de Boer; Tom H Korfage; Corina H G Metz; Marta Roccio; Marcel A G van der Heyden; Toon A B van Veen; Joost P G Sluijter; Pieter A Doevendans; Marie-José Goumans
Foetal and adult cardiomyocyte progenitor cells have different developmental potential.
Journal of cellular and molecular medicine 2010;14(4):861-70.
2010: Joost P G Sluijter; Alain van Mil; Patrick van Vliet; Corina H G Metz; Jia Liu; Pieter A Doevendans; Marie-José Goumans
MicroRNA-1 and -499 regulate differentiation and proliferation in human-derived cardiomyocyte progenitor cells.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(4):859-68.
2010: Fei Tian; Alex-Xianghua Zhou; Anke M Smits; Erik Larsson; Marie-José Goumans; Carl-Henrik Heldin; Jan Borén; Levent M Akyürek
Endothelial cells are activated during hypoxia via endoglin/ALK-1/SMAD1/5 signaling in vivo and in vitro.
Biochemical and biophysical research communications 2010;392(3):283-8.
2010: Simone Post; Anke M Smits; Alexandra J van den Broek; Joost P G Sluijter; Imo E Hoefer; Ben J Janssen; Repke J Snijder; Johannes J Mager; Gerard Pasterkamp; Christine L Mummery; Pieter A Doevendans; Marie-José Goumans
Impaired recruitment of HHT-1 mononuclear cells to the ischaemic heart is due to an altered CXCR4/CD26 balance.
Cardiovascular research 2010;85(3):494-502.
2010: Sara I Cunha; Evangelia Pardali; Midory Thorikay; Charlotte Anderberg; Lukas Hawinkels; Marie-José Goumans; Jasbir Seehra; Carl-Henrik Heldin; Peter ten Dijke; Kristian Pietras
Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.
The Journal of experimental medicine 2010;207(1):85-100.
2010: Peter E Westerweel; Cindy T J van Velthoven; Tri Q Nguyen; Krista den Ouden; Dominique P V de Kleijn; Marie-José Goumans; roel goldschmeding; Marianne C Verhaar
Modulation of TGF-β/BMP-6 expression and increased levels of circulating smooth muscle progenitor cells in a type I diabetes mouse model.
Cardiovascular diabetology 2010;9():55.
2010: Teun P de Boer; Toon A B van Veen; Malin Jonsson; Bart G J M Kok; Corina H G Metz; Joost P G Sluijter; Pieter A Doevendans; Jacques M T de Bakker; Marie-José Goumans; Michiel van der Heyden
Human cardiomyocyte progenitor cell-derived cardiomyocytes display a maturated electrical phenotype.
Journal of molecular and cellular cardiology 2010;48(1):254-60.
2009: Elizabeth M Winter; Angelique A M van Oorschot; Bianca Hogers; Linda M van der Graaf; Pieter A Doevendans; Robert E Poelmann; Douwe E Atsma; Adriana C Gittenberger-De Groot; Marie-José Goumans
A new direction for cardiac regeneration therapy: application of synergistically acting epicardium-derived cells and cardiomyocyte progenitor cells.
Circulation. Heart failure 2009;2(6):643-53.
2009: Zhen Liu; Kazuki Kobayashi; Maarten van Dinther; Sandra van Heiningen; Gudrun Valdimarsdottir; Theo van Laar; Marion Scharpfenecker; Clemens W G M Löwik; Marie-José Goumans; Peter Ten Dijke; Evangelia Pardali
VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.
Journal of cell science 2009;122(Pt 18):3294-302.
2009: Anke M Smits; Linda W van Laake; Krista den Ouden; Chantal Schreurs; Karoly Szuhai; Cees J A van Echteld; Christine L Mummery; Pieter A Doevendans; Marie-José Goumans
Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium.
Cardiovascular research 2009;83(3):527-35.
2009: Fumiko Itoh; Susumu Itoh; Rita L C Carvalho; Tomomi Adachi; Masatsugu Ema; Marie-José Goumans; Jonas Larsson; Stefan Karlsson; Satoru Takahashi; Christine L Mummery; Peter Ten Dijke; Mitsuyasu Kato
Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.
Laboratory investigation; a journal of technical methods and pathology 2009;89(7):800-10.
2009: Willy A Noort; Joost P G Sluijter; Marie-José Goumans; Steven A J Chamuleau; Pieter A Doevendans
Stem cells from in- or outside of the heart: isolation, characterization, and potential for myocardial tissue regeneration.
Pediatric cardiology 2009;30(5):699-709.
2009: Anke M Smits; Lisa G van den Hengel; Stieneke van den Brink; Corina H Metz; Pieter A Doevendans; Marie-José Goumans
A new in vitro model for stem cell differentiation and interaction.
Stem cell research 2009;2(2):108-12.
2009: Pieter T G Bot; Imo E Hoefer; Joost P G Sluijter; Patrick van Vliet; Anke M Smits; Franck Lebrin; Frans Moll; Jean-Paul de Vries; Pieter A Doevendans; Jan J Piek; Gerard Pasterkamp; Marie-José Goumans
Increased expression of the transforming growth factor-beta signaling pathway, endoglin, and early growth response-1 in stable plaques.
Stroke; a journal of cerebral circulation 2009;40(2):439-47.
2009: Anke M Smits; Patrick van Vliet; Corina H Metz; Tom Korfage; Joost P G Sluijter; Pieter A Doevendans; Marie-José Goumans
Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology.
Nature protocols 2009;4(2):232-43.
2009: Marie-José Goumans; Zhen Liu; Peter ten Dijke
TGF-beta signaling in vascular biology and dysfunction.
Cell research 2009;19(1):116-27.
2008: Marie-José Goumans; Anton-Jan van Zonneveld; Peter ten Dijke
Transforming growth factor beta-induced endothelial-to-mesenchymal transition: a switch to cardiac fibrosis?
Trends in cardiovascular medicine 2008;18(8):293-8.
2008: P van Vliet; Marta Roccio; A M Smits; A A M van Oorschot; C H G Metz; T A B van Veen; Joost P G Sluijter; Pieter A Doevendans; Marie-José Goumans
Progenitor cells isolated from the human heart: a potential cell source for regenerative therapy.
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 2008;16(5):163-9.
2008: Marta Roccio; Marie-José Goumans; J P G Sluijter; Pieter A Doevendans
Stem cell sources for cardiac regeneration.
Panminerva medica 2008;50(1):19-30.
2008: Leo Timmers; Joost P G Sluijter; J Karlijn Van Keulen; Imo E Hoefer; Marcel G J Nederhoff; Marie-José Goumans; Pieter A Doevendans; Cees J A van Echteld; Jaap A Joles; Paul H A Quax; Jan J Piek; Gerard Pasterkamp; Dominique P V de Kleijn
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction.
Circulation research 2008;102(2):257-64.
2008: Peter ten Dijke; Marie-José Goumans; Evangelia Pardali
Endoglin in angiogenesis and vascular diseases.
Angiogenesis 2008;11(1):79-89.
2008: Simone Post; Wouter Peeters; Els Busser; Dennis Lamers; Joost P G Sluijter; Marie-José Goumans; Roel A de Weger; Frans L Moll; Pieter A Doevendans; Gerard Pasterkamp; Aryan Vink
Balance between angiopoietin-1 and angiopoietin-2 is in favor of angiopoietin-2 in atherosclerotic plaques with high microvessel density.
Journal of vascular research 2008;45(3):244-50.
2007: Rita L C Carvalho; Fumiko Itoh; Marie-José Goumans; Franck Lebrin; Mitsuyasu Kato; Satoru Takahashi; Masatsugu Ema; Susumu Itoh; Marga van Rooijen; Philippe Bertolino; Peter ten Dijke; Christine L Mummery
Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice.
Journal of cell science 2007;120(Pt 24):4269-77.
2007: Marie-José Goumans; Teun de Boer; Anke M Smits; Linda W van Laake; Patrick van Vliet; Corina H G Metz; Tom H Korfage; K Peter Kats; Ron Hochstenbach; Gerard Pasterkamp; Marianne C Verhaar; Marcel A G van der Heyden; Dominique P V de Kleijn; Christine L Mummery; Toon A B van Veen; Joost P G Sluijter; Pieter A Doevendans
TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro.
Stem cell research 2007;1(2):138-49.
2007: Patrick van Vliet; Joost P G Sluijter; Pieter A Doevendans; Marie-José Goumans
Isolation and expansion of resident cardiac progenitor cells.
Expert review of cardiovascular therapy 2007;5(1):33-43.
2006: Linda W van Laake; Sander van den Driesche; Simone Post; Alie Feijen; maurits Jansen; Mariette H Driessens; Johannes J Mager; Repke J Snijder; Cornelius J J Westermann; Pieter A Doevendans; Cees J A van Echteld; Peter ten Dijke; Helen M Arthur; Marie-José Goumans; Franck Lebrin; Christine L Mummery
Endoglin has a crucial role in blood cell-mediated vascular repair.
Circulation 2006;114(21):2288-97.
2006: Nicolaas de Jonge; Marie-José Goumans; Daan Lips; Rutger J Hassink; Eva J Vlug; Roy van der Meel; Christopher Donald Emmerson; Joppe Nijman; Leon J De Windt; Pieter A Doevendans
Controlling cardiomyocyte survival.
Novartis Foundation symposium 2006;274():41-51; discussion 51-7, 152-5, 272-6.
2006: Gudrun Valdimarsdottir; Marie-José Goumans; Fumiko Itoh; Susumu Itoh; Carl-Henrik Heldin; Peter ten Dijke
Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells.
BMC cell biology 2006;7():16.
2005: Per Levéen; Maria Carlsén; Anna Makowska; Saemundur Oddsson; Jonas Larsson; Marie-José Goumans; Corrado M Cilio; Stefan Karlsson
TGF-beta type II receptor-deficient thymocytes develop normally but demonstrate increased CD8+ proliferation in vivo.
Blood 2005;106(13):4234-40.
2005: Joost P G Sluijter; Robert E Verloop; Wilco P C Pulskens; Evelyn Velema; Jos M Grimbergen; Paul H A Quax; Marie-José Goumans; Gerard Pasterkamp; Dominique P V de Kleijn
Involvement of furin-like proprotein convertases in the arterial response to injury.
Cardiovascular research 2005;68(1):136-43.
2005: Göran Karlsson; Yingchun Liu; Jonas Larsson; Marie-José Goumans; Ju Seog Lee; Snorri S Thorgeirsson; Markus Ringnér; Stefan Karlsson
Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.
Physiological genomics 2005;21(3):396-403.
2005: Anke M Smits; Patrick van Vliet; Rutger J Hassink; Marie-José Goumans; Pieter A Doevendans
The role of stem cells in cardiac regeneration.
Journal of cellular and molecular medicine 2005;9(1):25-36.
2004: Rita L C Carvalho; Leon Jonker; Marie-José Goumans; Jonas Larsson; Peter Bouwman; Stefan Karlsson; Peter Ten Dijke; Helen M Arthur; Christine L Mummery
Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia.
Development (Cambridge, England) 2004;131(24):6237-47.
2004: Franck Lebrin; Marie-José Goumans; Leon Jonker; Rita L C Carvalho; Gudrun Valdimarsdottir; Midory Thorikay; Christine Mummery; Helen M Arthur; Peter ten Dijke
Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.
The EMBO journal 2004;23(20):4018-28.
2004: Federica Chiara; Marie-José Goumans; Henrik Forsberg; Aive Ahgrén; Andrea Rasola; Pontus Aspenström; Christer Wernstedt; Carina Hellberg; Carl-Henrik Heldin; Rainer Heuchel
A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity.
The Journal of biological chemistry 2004;279(41):42516-27.
2004: Rutger J Hassink; Passier Robert; Marie-José Goumans; Christine L Mummery; Pieter A Doevendans
New and viable cells to replace lost and malfunctioning myocardial tissue.
Minerva cardioangiologica 2004;52(5):433-45.
2004: Rutger J Hassink; Marie-José Goumans; Christine L Mummery; Pieter A Doevendans
Human stem cells shape the future of cardiac regeneration research.
International journal of cardiology 2004;95 Suppl 1():S20-2.
2004: Fumiko Itoh; Susumu Itoh; Marie-José Goumans; Gudrun Valdimarsdottir; Tatsuya Iso; G Paolo Dotto; Yasuo Hamamori; Larry Kedes; Mitsuyasu Kato; Peter ten Dijke Pt
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.
The EMBO journal 2004;23(3):541-51.
2003: Peter ten Dijke; Olexander Korchynskyi; Gudrun Valdimarsdottir; Marie-José Goumans
Controlling cell fate by bone morphogenetic protein receptors.
Molecular and cellular endocrinology 2003;211(1-2):105-13.
2003: Jonas Larsson; Ulrika Blank; Hildur Helgadottir; Jon Mar Björnsson; Mats Ehinger; Marie-José Goumans; Xiaolong Fan; Per Levéen; Stefan Karlsson
TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro.
Blood 2003;102(9):3129-35.
2003: Marie-José Goumans; Gudrun Valdimarsdottir; Susumu Itoh; Franck Lebrin; Jonas Larsson; Christine Mummery; Stefan Karlsson; Peter ten Dijke
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
Molecular cell 2003;12(4):817-28.
2003: Marie-José Goumans; Franck Lebrin; Gudrun Valdimarsdottir
Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways.
Trends in cardiovascular medicine 2003;13(7):301-7.
2003: Peter Kloen; M Di Paola; Olivier Borens; Jeffrey Richmond; G Perino; David L Helfet; Marie-José Goumans
BMP signaling components are expressed in human fracture callus.
Bone 2003;33(3):362-71.
2003: Susana M Chuva de Sousa Lopes; Rita L C Carvalho; Sander van den Driesche; Marie-José Goumans; Peter ten Dijke; Christine L Mummery
Distribution of phosphorylated Smad2 identifies target tissues of TGF beta ligands in mouse development.
Gene expression patterns : GEP 2003;3(3):355-60.
2002: Peter Kloen; Steven B Doty; Eric Gordon; Iván F Rubel; Marie-José Goumans; David L Helfet
Expression and activation of the BMP-signaling components in human fracture nonunions.
The Journal of bone and joint surgery. American volume 2002;84-A(11):1909-18.
2002: Martijn Brugman; Marie-José Goumans; Alexander Rosendahl; Martijn Brugman; Susumu Itoh; Franck Lebrin; Paschalis Sideras; Peter ten Dijke
Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells.
Circulation 2002;106(17):2263-70.
2002: Wei He; Allen G Li; Dongyan Wang; Shuhua Han; B Zheng; Marie-José Goumans; Peter ten Dijke; Xiao-Jing Wang
Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues.
The EMBO journal 2002;21(11):2580-90.
2002: Sylviane Dennler; Marie-José Goumans; Peter ten Dijke
Transforming growth factor beta signal transduction.
Journal of leukocyte biology 2002;71(5):731-40.
2002: Marie-José Goumans; Gudrun Valdimarsdottir; Susumu Itoh; Alexander Rosendahl; Paschalis Sideras; Peter ten Dijke
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors.
The EMBO journal 2002;21(7):1743-53.
2002: Peter ten Dijke; Marie-José Goumans; Fumiko Itoh; Susumu Itoh
Regulation of cell proliferation by Smad proteins.
Journal of cellular physiology 2002;191(1):1-16.
2001: Jonas Larsson; Marie-José Goumans; L J Sjöstrand; Marga van Rooijen; D Ward; Per Levéen; X Xu; Peter ten Dijke; Christine L Mummery; Stefan Karlsson
Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice.
The EMBO journal 2001;20(7):1663-73.
2000: S Itoh; F Itoh; Marie-José Goumans; Peter ten Dijke
Signaling of transforming growth factor-beta family members through Smad proteins.
European journal of biochemistry / FEBS 2000;267(24):6954-67.
2000: An Zwijsen; Marga van Rooijen; Marie-José Goumans; N Dewulf; Erika A Bosman; Peter ten Dijke; Christine L Mummery; Danny Huylebroeck
Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;218(4):663-70.
2000: Henri A Kester; T M Ward-van Oostwaard; Marie-José Goumans; Marga van Rooijen; Paul T van der Saag; Bart van der Burg; Christine L Mummery
Expression of TGF-beta stimulated clone-22 (TSC-22) in mouse development and TGF-beta signalling.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;218(4):563-72.
2000: Marie-José Goumans; Christine Mummery
Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.
The International journal of developmental biology 2000;44(3):253-65.
1999: Marie-José Goumans; An Zwijsen; Marga van Rooijen; Danny Huylebroeck; Bernard A J Roelen; Christine L Mummery
Transforming growth factor-beta signalling in extraembryonic mesoderm is required for yolk sac vasculogenesis in mice.
Development (Cambridge, England) 1999;126(16):3473-83.
1999: Sólveig Thorsteinsdóttir; Bernard A J Roelen; Marie-José Goumans; Dorien Ward-van Oostwaard; A C Gaspar; Christine L Mummery
Expression of the alpha 6A integrin splice variant in developing mouse embryonic stem cell aggregates and correlation with cardiac muscle differentiation.
Differentiation; research in biological diversity 1999;64(3):173-84.
1999: An Zwijsen; Marie-José Goumans; Kirstie A Lawson; Marga van Rooijen; Christine L Mummery
Ectopic expression of the transforming growth factor beta type II receptor disrupts mesoderm organisation during mouse gastrulation.
Developmental dynamics : an official publication of the American Association of Anatomists 1999;214(2):141-51.
1998: Bernard A J Roelen; Marie-José Goumans; An Zwijsen; Christine L Mummery
Identification of two distinct functions for TGF-beta in early mouse development.
Differentiation; research in biological diversity 1998;64(1):19-31.
1998: Marie-José Goumans; Dorien Ward-van Oostwaard; F Wianny; Pierre Savatier; An Zwijsen; Christine Mummery
Mouse embryonic stem cells with aberrant transforming growth factor beta signalling exhibit impaired differentiation in vitro and in vivo.
Differentiation; research in biological diversity 1998;63(3):101-13.
1998: Christian Baudoin; Marie-José Goumans; Christine Mummery; Arnoud Sonnenberg
Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.
Genes & development 1998;12(8):1202-16.
1997: Bernard A J Roelen; Marie-José Goumans; Marga van Rooijen; Christine L Mummery
Differential expression of BMP receptors in early mouse development.
The International journal of developmental biology 1997;41(4):541-9.
1995: Kristin Verschueren; N Dewulf; Marie-José Goumans; O Lonnoy; A Feijen; Susanne Grimsby; K Vandi Spiegle; Peter ten Dijke; A Morén; Patrick Vanscheeuwijck; Carl-Henrik Heldin; Kohei Miyazono; C Mummery; J Van Den Eijnden-Van Raaij; Danny Huylebroeck
Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis.
Mechanisms of development 1995;52(1):109-23.
1994: A Feijen; Marie-José Goumans; AJ van den Eijnden-van Raaij
Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins.
Development (Cambridge, England) 1994;120(12):3621-37.