FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Lutz Graeve

Research Profile

Chemicals & Drugs

Physiology

Anatomy

Concepts & Ideas

Molecular Sequence Data

Living Beings

Dogs

Co-author Network

Publications

TOP 3
Fernanda D B Abadio Finco; Sabrina Böser; Reinhold Carle; Dietmar R Kammerer; Wen-Hsin Tseng; Lutz Graeve
Antioxidant activity and characterization of phenolic compounds from bacaba (Oenocarpus bacaba Mart.) fruit by HPLC-DAD-MS(n).
Anja Osterhues; Sibylle Liebmann; Monika Schmid; Deborah M Buk; Ralf Huss; Lutz Graeve; Evelyn Zeindl-Eberhart
Stem cells and experimental leukemia can be distinguished by lipid raft protein composition.
Jordan A Doumanov; Merle Daubrawa; Heike Unden; Lutz Graeve
Identification of a basolateral sorting signal within the cytoplasmic domain of the interleukin-6 signal transducer gp130.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Lutz Graeve (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Fernanda D B Abadio Finco; Sabrina Böser; Reinhold Carle; Dietmar R Kammerer; Wen-Hsin Tseng; Lutz Graeve
Antioxidant activity and characterization of phenolic compounds from bacaba (Oenocarpus bacaba Mart.) fruit by HPLC-DAD-MS(n).
Journal of agricultural and food chemistry 2012;60(31):7665-73.
2006: Anja Osterhues; Sibylle Liebmann; Monika Schmid; Deborah M Buk; Ralf Huss; Lutz Graeve; Evelyn Zeindl-Eberhart
Stem cells and experimental leukemia can be distinguished by lipid raft protein composition.
Stem cells and development 2006;15(5):677-86.
2006: Jordan A Doumanov; Merle Daubrawa; Heike Unden; Lutz Graeve
Identification of a basolateral sorting signal within the cytoplasmic domain of the interleukin-6 signal transducer gp130.
Cellular signalling 2006;18(8):1140-6.
2005: Deborah M Buk; Olga Renner; Lutz Graeve
Increased association with detergent-resistant membranes/lipid rafts of apically targeted mutants of the interleukin-6 receptor gp80.
European journal of cell biology 2005;84(10):819-31.
2004: Deborah M Buk; Michaela Waibel; Claudia Braig; Astrid S Martens; Peter C Heinrich; Lutz Graeve
Polarity and lipid raft association of the components of the ciliary neurotrophic factor receptor complex in Madin-Darby canine kidney cells.
Journal of cell science 2004;117(Pt 10):2063-75.
2001: L Terstegen; P Gatsios; Stephan Ludwig; S Pleschka; Willi Jahnen-Dechent; Peter C Heinrich; Lutz Graeve
The vesicular stomatitis virus matrix protein inhibits glycoprotein 130-dependent STAT activation.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5209-16.
2001: Johannes Bode; R Fischer; Dieter Häussinger; Lutz Graeve; Peter C Heinrich; Fred Schaper
The inhibitory effect of IL-1 beta on IL-6-induced alpha 2-macroglobulin expression is due to activation of NF-kappa B.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1469-81.
2001: Peter C Heinrich; J Bode; M Decker; Lutz Graeve; Astrid S Martens; Gerhard Müller-Newen; S Pflanz; Fred Schaper; Jochen Schmitz
Termination and modulation of IL-6-type cytokine signaling.
Advances in experimental medicine and biology 2001;495():153-60.
2000: Ralf Huss; Eva M Weissinger; C Lange; P Gatsios; Günther Eissner; Hans-Jochem Kolb; Joachim Diebold; Peter C Heinrich; Lutz Graeve
In vitro-generated stem cell leukaemia showing altered cell cycle progression with distinct signalling of the tyrosine-phosphorylated rasGAP-associated p62(dok) protein.
The Journal of pathology 2000;192(3):363-72.
2000: Astrid S Martens; Johannes Bode; P C Heinrich; Lutz Graeve
The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized madin-darby canine kidney cells.
Journal of cell science 2000;113 ( Pt 20)():3593-602.
2000: Peter C Heinrich; Johannes Bode; Lutz Graeve; Claude Haan; Astrid S Martens; Gerhard Müller-Newen; Ariane Nimmesgern; Fred Schaper; Jochen Schmitz; Elmar Siewert
Modulation and termination of interleukin-6 signalling.
European cytokine network 2000;11(3):512-3.
2000: Ralf Huss; P Gatsios; Lutz Graeve; C Lange; Günther Eissner; Hans-Jochem Kolb; K Thalmeier; Peter C Heinrich
Quiescence of CD34-negative haematopoietic stem cells is mediated by downregulation of Cyclin B and no stat activation.
Cytokine 2000;12(8):1195-204.
2000: L Terstegen; B G Maassen; Simone Radtke; Iris Behrmann; Fred Schaper; Peter C Heinrich; Lutz Graeve; P Gatsios
Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA.
FEBS letters 2000;478(1-2):100-4.
2000: L Terstegen; P Gatsios; Johannes Bode; Fred Schaper; Peter C Heinrich; Lutz Graeve
The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130.
The Journal of biological chemistry 2000;275(25):18810-7.
2000: S Thiel; Ulrike Sommer; Marcin Kortylewski; Claude Haan; Iris Behrmann; Peter C Heinrich; Lutz Graeve
Termination of IL-6-induced STAT activation is independent of receptor internalization but requires de novo protein synthesis.
FEBS letters 2000;470(1):15-9.
1999: Johannes Bode; Ariane Nimmesgern; Jochen Schmitz; Fred Schaper; M Schmitt; W Frisch; Dieter Häussinger; Peter C Heinrich; Lutz Graeve
LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages.
FEBS letters 1999;463(3):365-70.
1999: Johannes Bode; P Gatsios; Stephan Ludwig; U R Rapp; Dieter Häussinger; Peter C Heinrich; Lutz Graeve
The mitogen-activated protein (MAP) kinase p38 and its upstream activator MAP kinase kinase 6 are involved in the activation of signal transducer and activator of transcription by hyperosmolarity.
The Journal of biological chemistry 1999;274(42):30222-7.
1999: S Thiel; Iris Behrmann; Andreas Timmermann; Heike Dahmen; Gerhard Müller-Newen; Fred Schaper; Jan Tavernier; V Pitard; Peter C Heinrich; Lutz Graeve
Identification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor.
The Biochemical journal 1999;339 ( Pt 1)():15-9.
1998: S Thiel; Heike Dahmen; Astrid S Martens; Gerhard Müller-Newen; Fred Schaper; Peter C Heinrich; Lutz Graeve
Constitutive internalization and association with adaptor protein-2 of the interleukin-6 signal transducer gp130.
FEBS letters 1998;441(2):231-4.
1998: Gerhard Müller-Newen; Andrea Küster; U Hemmann; R Keul; U Horsten; Astrid S Martens; Lutz Graeve; John Wijdenes; Peter C Heinrich
Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6347-55.
1998: P Gatsios; L Terstegen; F Schliess; Dieter Häussinger; Ian M Kerr; Peter C Heinrich; Lutz Graeve
Activation of the Janus kinase/signal transducer and activator of transcription pathway by osmotic shock.
The Journal of biological chemistry 1998;273(36):22962-8.
1998: Peter C Heinrich; Iris Behrmann; Gerhard Müller-Newen; Fred Schaper; Lutz Graeve
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway.
The Biochemical journal 1998;334 ( Pt 2)():297-314.
1998: S Thiel; Iris Behrmann; E Dittrich; Leon Muys; Jan Tavernier; John Wijdenes; Peter C Heinrich; Lutz Graeve
Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway.
The Biochemical journal 1998;330 ( Pt 1)():47-54.
1998: Peter C Heinrich; Friedemann Horn; Lutz Graeve; E Dittrich; Ian M Kerr; Gerhard Müller-Newen; Joachim Grötzinger; Axel Wollmer
Interleukin-6 and related cytokines: effect on the acute phase reaction.
Zeitschrift für Ernährungswissenschaft 1998;37 Suppl 1():43-9.
1997: T A Korolenko; P K Heinrich; U Hemmann; O Weiergraber; E Dittrich; Lutz Graeve
[Cell endocytosis of the complex interleukin-6-soluble interleukin-6 receptor and its intralysosomal degradation].
Biulleten' eksperimental'noĭ biologii i meditsiny 1997;124(11):527-9.
1997: Gabriele Zwadlo-Klarwasser; W Hamann; P Gatsios; Lutz Graeve; W Schmutzler
Expression of interleukin-6 receptor subunits in human macrophage subsets.
International archives of allergy and immunology 1997;113(1-3):300-1.
1997: Iris Behrmann; C Janzen; Claudia Gerhartz; Hildegard Schmitz-Van De Leur; Heike M Hermanns; B Heesel; Lutz Graeve; Friedemann Horn; Jan Tavernier; Peter C Heinrich
A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation.
The Journal of biological chemistry 1997;272(8):5269-74.
1996: Lutz Graeve; T A Korolenko; U Hemmann; O Weiergräber; E Dittrich; Peter C Heinrich
A complex of the soluble interleukin-6 receptor and interleukin-6 is internalized via the signal transducer gp130.
FEBS letters 1996;399(1-2):131-4.
1996: P Gatsios; HD Haubeck; E Van de Leur; W Frisch; S S Apte; H Greiling; Peter C Heinrich; Lutz Graeve
Oncostatin M differentially regulates tissue inhibitors of metalloproteinases TIMP-1 and TIMP-3 gene expression in human synovial lining cells.
European journal of biochemistry / FEBS 1996;241(1):56-63.
1996: P May; C Gerhartz; B Heesel; Thomas Welte; Wolfgang Doppler; Lutz Graeve; Friedemann Horn; Peter C Heinrich
Comparative study on the phosphotyrosine motifs of different cytokine receptors involved in STAT5 activation.
FEBS letters 1996;394(2):221-6.
1996: U Hemmann; C Gerhartz; B Heesel; J Sasse; G Kurapkat; Joachim Grötzinger; Axel Wollmer; Z Zhong; J E Darnell; Lutz Graeve; Peter C Heinrich; Friedemann Horn
Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation.
The Journal of biological chemistry 1996;271(22):12999-3007.
1996: C Gerhartz; B Heesel; J Sasse; U Hemmann; Christiane Landgraf; Jens Schneider-Mergener; Friedemann Horn; Peter C Heinrich; Lutz Graeve
Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation.
The Journal of biological chemistry 1996;271(22):12991-8.
1996: E Dittrich; C R Haft; Leon Muys; Peter C Heinrich; Lutz Graeve
A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor.
The Journal of biological chemistry 1996;271(10):5487-94.
1995: Marcin Bugno; Lutz Graeve; P Gatsios; Aleksander Koj; Peter C Heinrich; James Travis; Tomasz Kordula
Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter.
Nucleic acids research 1995;23(24):5041-7.
1995: P Kurschat; Lutz Graeve; A Erren; P Gatsios; Stefan Rose-John; Elke Roeb; Harald Tschesche; Aleksander Koj; Peter C Heinrich
Expression of a biologically active murine tissue inhibitor of metalloproteinases-1 (TIMP-1) in baculovirus-infected insect cells. Purification and tissue distribution in the rat.
European journal of biochemistry / FEBS 1995;234(2):485-91.
1995: Elke Roeb; Lutz Graeve; Jürgen Müllberg; Siegfried Matern; Stefan Rose-John
TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes.
Annals of the New York Academy of Sciences 1995;762():462-4.
1995: E Dittrich; C Gerhartz; Stefan Rose-John; Jürgen Müllberg; T Stoyan; Peter C Heinrich; Lutz Graeve
A region within the cytoplasmic domain of the interleukin-6 signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor.
Annals of the New York Academy of Sciences 1995;762():410-2.
1995: Peter C Heinrich; Lutz Graeve; Stefan Rose-John; Jens Schneider-Mergener; E Dittrich; A Erren; C Gerhartz; U Hemann; C Lütticken; U Wegenka
Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction.
Annals of the New York Academy of Sciences 1995;762():222-36; discussion 236-7.
1995: Elke Roeb; Stefan Rose-John; A Erren; D R Edwards; Siegfried Matern; Lutz Graeve; Peter C Heinrich
Tissue inhibitor of metalloproteinases-2 (TIMP-2) in rat liver cells is increased by lipopolysaccharide and prostaglandin E2.
FEBS letters 1995;357(1):33-6.
1994: Elke Roeb; Lutz Graeve; Jürgen Müllberg; Siegfried Matern; Stefan Rose-John
TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes.
FEBS letters 1994;349(1):45-9.
1994: E Dittrich; Stefan Rose-John; C Gerhartz; Jürgen Müllberg; T Stoyan; K Yasukawa; Peter C Heinrich; Lutz Graeve
Identification of a region within the cytoplasmic domain of the interleukin-6 (IL-6) signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor.
The Journal of biological chemistry 1994;269(29):19014-20.
1994: C Gerhartz; E Dittrich; T Stoyan; Stefan Rose-John; K Yasukawa; Peter C Heinrich; Lutz Graeve
Biosynthesis and half-life of the interleukin-6 receptor and its signal transducer gp130.
European journal of biochemistry / FEBS 1994;223(1):265-74.
1994: M Schoester; Peter C Heinrich; Lutz Graeve
Regulation of interleukin-6 receptor expression by interleukin-6 in human monocytes--a re-examination.
FEBS letters 1994;345(2-3):131-4.
1994: Jürgen Müllberg; W Oberthür; F Lottspeich; E Mehl; E Dittrich; Lutz Graeve; Peter C Heinrich; Stefan Rose-John
The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(10):4958-68.
1993: Elke Roeb; Lutz Graeve; R Hoffmann; K Decker; D R Edwards; Peter C Heinrich
Regulation of tissue inhibitor of metalloproteinases-1 gene expression by cytokines and dexamethasone in rat hepatocyte primary cultures.
Hepatology (Baltimore, Md.) 1993;18(6):1437-42.
1993: Stefan Rose-John; H Schooltink; Hildegard Schmitz-Van De Leur; Jürgen Müllberg; Peter C Heinrich; Lutz Graeve
Intracellular retention of interleukin-6 abrogates signaling.
The Journal of biological chemistry 1993;268(29):22084-91.
1993: Jürgen Müllberg; E Dittrich; Lutz Graeve; C Gerhartz; K Yasukawa; T Taga; T Kishimoto; Peter C Heinrich; Stefan Rose-John
Differential shedding of the two subunits of the interleukin-6 receptor.
FEBS letters 1993;332(1-2):174-8.
1993: Lutz Graeve; M Baumann; P C Heinrich
Interleukin-6 in autoimmune disease. Role of IL-6 in physiology and pathology of the immune defense.
The Clinical investigator 1993;71(8):664-71.
1993: M van Dam; Jürgen Müllberg; H Schooltink; T Stoyan; J P Brakenhoff; Lutz Graeve; Peter C Heinrich; Stefan Rose-John
Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding.
The Journal of biological chemistry 1993;268(20):15285-90.
1993: D Pietzko; D Zohlnhöfer; Lutz Graeve; D Fleischer; T Stoyan; H Schooltink; Stefan Rose-John; Peter C Heinrich
The hepatic interleukin-6 receptor. Studies on its structure and regulation by phorbol 12-myristate 13-acetate-dexamethasone.
The Journal of biological chemistry 1993;268(6):4250-8.
1993: Jürgen Müllberg; H Schooltink; T Stoyan; M Günther; Lutz Graeve; G Buse; Andrzej mackiewicz; Peter C Heinrich; Stefan Rose-John
The soluble interleukin-6 receptor is generated by shedding.
European journal of immunology 1993;23(2):473-80.
1992: Tomasz Kordula; I Güttgemann; Stefan Rose-John; Elke Roeb; A Osthues; Harald Tschesche; Aleksander Koj; Peter C Heinrich; Lutz Graeve
Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in human hepatoma cells (HepG2). Up-regulation by interleukin-6 and transforming growth factor beta 1.
FEBS letters 1992;313(2):143-7.
1992: D Zohlnhöfer; Lutz Graeve; Stefan Rose-John; H Schooltink; E Dittrich; Peter C Heinrich
The hepatic interleukin-6 receptor. Down-regulation of the interleukin-6 binding subunit (gp80) by its ligand.
FEBS letters 1992;306(2-3):219-22.