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László Gráf

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Genes & Molecular Sequences

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Anna Rauscher; Imre Derényi; László Gráf; András Málnási-Csizmadia
Internal friction in enzyme reactions.
Krisztián Vörös; Edit Kaszás; Zoltan Prohaszka ; Péter Szenthe; Zoltán Böröcz; Károly Cseh; László Gráf; László Gráf; László Kalabay
Serum fetuin-A in metabolic and inflammatory pathways in patients with myocardial infarction.
Julianna Kardos; András Micsonai; Henriett Pál-Gábor; Éva Petrik; László Gráf; János Kovács; Young-Ho Lee; Hironobu Naiki; Yuji Goto
Reversible heat-induced dissociation of β2-microglobulin amyloid fibrils.

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2013: Anna Rauscher; Imre Derényi; László Gráf; András Málnási-Csizmadia
Internal friction in enzyme reactions.
IUBMB life 2013;65(1):35-42.
2011: Krisztián Vörös; Edit Kaszás; Zoltan Prohaszka ; Péter Szenthe; Zoltán Böröcz; Károly Cseh; László Gráf; László Gráf; László Kalabay
Serum fetuin-A in metabolic and inflammatory pathways in patients with myocardial infarction.
European journal of clinical investigation 2011;41(7):703-9.
2011: Julianna Kardos; András Micsonai; Henriett Pál-Gábor; Éva Petrik; László Gráf; János Kovács; Young-Ho Lee; Hironobu Naiki; Yuji Goto
Reversible heat-induced dissociation of β2-microglobulin amyloid fibrils.
Biochemistry 2011;50(15):3211-20.
2010: Krisztián Tárnok; László Szilágyi; Timea Berki; Péter Németh; László Gráf; Katalin Schlett
Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes.
Journal of neurochemistry 2010;115(2):314-24.
2008: Julianna Kardos; Veronika Harmat; Anna Palló; Orsolya Barabás; Katalin Szilágyi; László Gráf; Gábor Náray-Szabó; Yuji Goto; Péter Závodszky; Péter Gál
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.
Molecular immunology 2008;45(6):1752-60.
2008: Linda Gombos; Julianna Kardos; András Patthy; Péter Medveczky; László Szilágyi; András Málnási-Csizmadia; László Gráf
Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges.
Biochemistry 2008;47(6):1675-84.
2008: Balázs Jelinek; Gergely Katona; Krisztián Fodor; István Venekei; László Gráf
The crystal structure of a trypsin-like mutant chymotrypsin: the role of position 226 in the activity and specificity of S189D chymotrypsin.
The protein journal 2008;27(2):79-87.
2007: Judit Tóth; Erika Siklódi; Péter Medveczky; Katalin Gallatz; Péter Németh; László Szilágyi; László Gráf; Miklós Palkovits
Regional distribution of human trypsinogen 4 in human brain at mRNA and protein level.
Neurochemical research 2007;32(9):1423-33.
2007: Borbála Szenthe; András Patthy; Zoltán Gáspári; Adrienna Katalin Kékesi; László Gráf; Gabor Pal
When the surface tells what lies beneath: combinatorial phage-display mutagenesis reveals complex networks of surface-core interactions in the pacifastin protease inhibitor family.
Journal of molecular biology 2007;370(1):63-79.
2007: Judit Tóth; Zoltán Simon; Péter Medveczky; Linda Gombos; Balázs Jelinek; László Szilágyi; László Gráf; András Málnási-Csizmadia
Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: role of local internal viscosity in protein dynamics.
Proteins 2007;67(4):1119-27.
2007: Judit Marokházi; Nikolett Mihala; Ferenc Hudecz; Andras Fodor; László Gráf; István Venekei
Cleavage site analysis of a serralysin-like protease, PrtA, from an insect pathogen Photorhabdus luminescens and development of a highly sensitive and specific substrate.
The FEBS journal 2007;274(8):1946-56.
2007: Katalin Gallatz; Péter Medveczky; Péter Németh; László Szilágyi; László Gráf; Miklós Palkovits
Human trypsin(ogen) 4-like immunoreactivity in the white matter of the cerebral cortex and the spinal cord.
Ideggyógyászati szemle 2007;60(3-4):118-23.
2007: Attila L Németh; Péter Medveczky; Judit Tóth; Erika Siklódi; Katalin Schlett; András Patthy; Miklós Palkovits; Judit Ovádi; Natália Tõkési; Péter Németh; László Szilágyi; László Gráf
Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N-terminal leucine. A possible means to regulate gene expression.
The FEBS journal 2007;274(6):1610-20.
2007: László Kalabay; László Gráf; Krisztián Vörös; László Jakab; Zsuzsa Benko; László Telegdy; Béla Fekete; Zoltan Prohaszka ; George Füst
Human serum fetuin A/alpha2HS-glycoprotein level is associated with long-term survival in patients with alcoholic liver cirrhosis, comparison with the Child-Pugh and MELD scores.
BMC gastroenterology 2007;7():15.
2006: Csaba Ruzics; András Folyovich; Agnes Fehér; Zsuzsanna Arányi; László Gráf; Judit Várkonyi
[Churg-Strauss syndrome complicated by polyneuropathy].
Orvosi hetilap 2006;147(19):899-901.
2006: Judit Tóth; Linda Gombos; Zoltán Simon; Péter Medveczky; László Szilágyi; László Gráf; András Málnási-Csizmadia
Thermodynamic analysis reveals structural rearrangement during the acylation step in human trypsin 4 on 4-methylumbelliferyl 4-guanidinobenzoate substrate analogue.
The Journal of biological chemistry 2006;281(18):12596-602.
2006: Zoltán Gáspári; Borbála Szenthe; András Patthy; William M Westler; László Gráf; András Perczel
Local binding with globally distributed changes in a small protease inhibitor upon enzyme binding.
The FEBS journal 2006;273(8):1831-42.
2006: Krisztián Fodor; Veronika Harmat; Richard Neutze; László Szilágyi; László Gráf; Gergely Katona
Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis.
Biochemistry 2006;45(7):2114-21.
2006: Péter Medveczky; József Antal; András Patthy; Katalin A Kékesi; Gábor Juhász; László Szilágyi; László Gráf
Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4.
FEBS letters 2006;580(2):545-52.
2005: Krisztián Fodor; Veronika Harmat; Csaba Hetényi; Julianna Kardos; József Antal; András Perczel; András Patthy; Gergely Katona; László Gráf
Extended intermolecular interactions in a serine protease-canonical inhibitor complex account for strong and highly specific inhibition.
Journal of molecular biology 2005;350(1):156-69.
2005: Mihály Kondrák; János Kutas; Borbála Szenthe; András Patthy; Zsófia Bánfalvi; Miklós Nádasy; László Gráf; Bence Asbóth
Inhibition of Colorado potato beetle larvae by a locust proteinase inhibitor peptide expressed in potato.
Biotechnology letters 2005;27(12):829-34.
2005: Borbála Szenthe; Carminita Frost; László Szilágyi; András Patthy; Ryno J Naudé; László Gráf
Cloning and expression of ostrich trypsinogen: an avian trypsin with a highly sensitive autolysis site.
Biochimica et biophysica acta 2005;1748(1):35-42.
2004: Judit Marokházi; Katalin Lengyel; Szilvia Pekár; Gabriella Felfoldi; András Patthy; László Gráf; Andras Fodor; István Venekei
Comparison of proteolytic activities produced by entomopathogenic Photorhabdus bacteria: strain- and phase-dependent heterogeneity in composition and activity of four enzymes.
Applied and environmental microbiology 2004;70(12):7311-20.
2004: Judit Marokházi; György Kóczán; Ferenc Hudecz; László Gráf; Andras Fodor; István Venekei
Enzymic characterization with progress curve analysis of a collagen peptidase from an enthomopathogenic bacterium, Photorhabdus luminescens.
The Biochemical journal 2004;379(Pt 3):633-40.
2004: Borbála Szenthe; Zoltán Gáspári; Attila Nagy; András Perczel; László Gráf
Same fold with different mobility: backbone dynamics of small protease inhibitors from the desert locust, Schistocerca gregaria.
Biochemistry 2004;43(12):3376-84.
2004: Gabor Pal; András Patthy; József Antal; László Gráf
Mutant rat trypsin selectively cleaves tyrosyl peptide bonds.
Analytical biochemistry 2004;326(2):190-9.
2004: Balázs Jelinek; József Antal; István Venekei; László Gráf
Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease.
Protein engineering, design & selection : PEDS 2004;17(2):127-31.
2004: János Kutas; Mihály Kondrák; Borbála Szenthe; András Patthy; Zsófia Bánfalvi; Miklós Nádasy; László Gráf; Bence Asbóth
Colorado potato beetle larvae on potato plants expressing a locust proteinase inhibitor.
Communications in agricultural and applied biological sciences 2004;69(3):281-7.
2003: Anna Biró; Zoltán Hérincs; Erzsébet Fellinger; László Szilágyi; Zsuzsa Barad; János Gergely; László Gráf; Gabriella Sármay
Characterization of a trypsin-like serine protease of activated B cells mediating the cleavage of surface proteins.
Biochimica et biophysica acta 2003;1624(1-3):60-9.
2003: Erika Szabó; István Venekei; Zsolt Bocskei; Gábor Náray-Szabó; László Gráf
Three dimensional structures of S189D chymotrypsin and D189S trypsin mutants: the effect of polarity at site 189 on a protease-specific stabilization of the substrate-binding site.
Journal of molecular biology 2003;331(5):1121-30.
2003: Géza Ambrus; Péter Gál; Mayumi Kojima; Katalin Szilágyi; Júlia Balczer; József Antal; László Gráf; Andreas Laich; Beryl E Moffatt; Wilhelm J Schwaeble; Robert B Sim; Péter Závodszky
Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1374-82.
2002: András Patthy; Sumaira Amir; Zulfiquar Malik; Arpád Bódi; Julianna Kardos; Bence Asbóth; László Gráf
Remarkable phylum selectivity of a Schistocerca gregaria trypsin inhibitor: the possible role of enzyme-inhibitor flexibility.
Archives of biochemistry and biophysics 2002;398(2):179-87.
2002: Gergely Katona; Gunnar I Berglund; Janos Hajdu; László Gráf; László Szilágyi
Crystal structure reveals basis for the inhibitor resistance of human brain trypsin.
Journal of molecular biology 2002;315(5):1209-18.
2002: Zoltán Gáspári; András Patthy; László Gráf; András Perczel
Comparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregaria.
European journal of biochemistry / FEBS 2002;269(2):527-37.
2001: Arpád Bódi; G Kaslik; István Venekei; László Gráf
Structural determinants of the half-life and cleavage site preference in the autolytic inactivation of chymotrypsin.
European journal of biochemistry / FEBS 2001;268(23):6238-46.
2001: Julianna Kardos; Péter Gál; László Szilágyi; Nicole M Thielens; Katalin Szilágyi; Z Lõrincz; P Kulcsár; László Gráf; Gérard J Arlaud; Péter Závodszky
The role of the individual domains in the structure and function of the catalytic region of a modular serine protease, C1r.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5202-8.
2001: László Szilágyi; E Kénesi; Gergely Katona; G Kaslik; Gábor Juhász; László Gráf
Comparative in vitro studies on native and recombinant human cationic trypsins. Cathepsin B is a possible pathological activator of trypsinogen in pancreatitis.
The Journal of biological chemistry 2001;276(27):24574-80.
2001: József Antal; Gabor Pal; Bence Asbóth; Zsuzsanna Buzás; András Patthy; László Gráf
Specificity assay of serine proteinases by reverse-phase high-performance liquid chromatography analysis of competing oligopeptide substrate library.
Analytical biochemistry 2001;288(2):156-67.
1999: Miklós Sahin-Tóth; László Gráf; M Tóth
Trypsinogen stabilization by mutation Arg117-->His: a unifying pathomechanism for hereditary pancreatitis?
Biochemical and biophysical research communications 1999;264(2):505-8.
1999: Julianna Kardos; Arpád Bódi; Péter Závodszky; István Venekei; László Gráf
Disulfide-linked propeptides stabilize the structure of zymogen and mature pancreatic serine proteases.
Biochemistry 1999;38(38):12248-57.
1999: Z Malik; S Amir; Gabor Pal; Zsuzsanna Buzás; E Várallyay; József Antal; Zoltan Szilágyi; Károly Vékey; Bence Asbóth; András Patthy; László Gráf
Proteinase inhibitors from desert locust, Schistocerca gregaria: engineering of both P(1) and P(1)' residues converts a potent chymotrypsin inhibitor to a potent trypsin inhibitor.
Biochimica et biophysica acta 1999;1434(1):143-50.
1999: Erika Szabó; Zsolt Bocskei; Gábor Náray-Szabó; László Gráf
The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease.
European journal of biochemistry / FEBS 1999;263(1):20-6.
1999: G Kaslik; William M Westler; László Gráf; John Lute Markley
Properties of the His57-Asp102 dyad of rat trypsin D189S in the zymogen, activated enzyme, and alpha1-proteinase inhibitor complexed forms.
Archives of biochemistry and biophysics 1999;362(2):254-64.
1999: P Hudáky; G Kaslik; István Venekei; László Gráf
The differential specificity of chymotrypsin A and B is determined by amino acid 226.
European journal of biochemistry / FEBS 1999;259(1-2):528-33.
1998: E Várallyay; Gabor Pal; András Patthy; László Szilágyi; László Gráf
Two mutations in rat trypsin confer resistance against autolysis.
Biochemical and biophysical research communications 1998;243(1):56-60.
1997: G Kaslik; Julianna Kardos; Erika Szabó; László Szilágyi; Péter Závodszky; William M Westler; John Lute Markley; László Gráf
Effects of serpin binding on the target proteinase: global stabilization, localized increased structural flexibility, and conserved hydrogen bonding at the active site.
Biochemistry 1997;36(18):5455-64.
1997: E Várallyay; Z Lengyel; László Gráf; László Szilágyi
The role of disulfide bond C191-C220 in trypsin and chymotrypsin.
Biochemical and biophysical research communications 1997;230(3):592-6.
1996: Gabor Pal; László Szilágyi; László Gráf
Stable monomeric form of an originally dimeric serine proteinase inhibitor, ecotin, was constructed via site directed mutagenesis.
FEBS letters 1996;385(3):165-70.
1996: István Venekei; László Szilágyi; László Gráf; W J Rutter
Attempts to convert chymotrypsin to trypsin.
FEBS letters 1996;383(1-2):143-7.
1996: István Venekei; László Szilágyi; László Gráf; W J Rutter
Attempts to convert chymotrypsin to trypsin.
FEBS letters 1996;379(2):143-7.
1996: István Venekei; László Gráf; W J Rutter
Expression of rat chymotrypsinogen in yeast: a study on the structural and functional significance of the chymotrypsinogen propeptide.
FEBS letters 1996;379(2):139-42.
1995: G Kaslik; András Patthy; M Bálint; László Gráf
Trypsin complexed with alpha 1-proteinase inhibitor has an increased structural flexibility.
FEBS letters 1995;370(3):179-83.
1994: László Nyitray; A Jancsó; Y Ochiai; László Gráf; Andrew G Szent-Györgyi
Scallop striated and smooth muscle myosin heavy-chain isoforms are produced by alternative RNA splicing from a single gene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12686-90.
1994: Enyedi Peter; Gyorgy Szabadkai; Andrea Horváth; László Szilágyi; László Gráf; András Spät
Inositol 1,4,5-trisphosphate receptor subtypes in adrenal glomerulosa cells.
Endocrinology 1994;134(6):2354-9.
1994: Gabor Pal; G Sprengel; András Patthy; László Gráf
Alteration of the specificity of ecotin, an E. coli serine proteinase inhibitor, by site directed mutagenesis.
FEBS letters 1994;342(1):57-60.
1993: László Polgár; F Erdélyi; E Hajnal; M Löw; László Gráf; B D Korant
Separation of native and truncated forms of poliovirus protease 3C produced in Escherichia coli.
The Biochemical journal 1993;290 ( Pt 3)():797-800.
1991: Lizbeth Hedstrom; László Gráf; Caro-Beth Stewart; W J Rutter; M A Phillips
Modulation of enzyme specificity by site-directed mutagenesis.
Methods in enzymology 1991;202():671-87.
1990: Miklós Hollósi; Helga Süli-Vargha; Katalin F Medzihradszky; G D Fasman; George Kunos; László Gráf
Structural determinants of the binding of gliadin fragments to human peripheral blood lymphocytes.
Neuropeptides 1990;17(3):111-6.
1988: László Gráf; G Hegyi; István Likó; J Hepp; Katalin F Medzihradszky; Charles S Craik; W J Rutter
Structural and functional integrity of specificity and catalytic sites of trypsin.
International journal of peptide and protein research 1988;32(6):512-8.
1988: László Gráf; A Jancsó; László Szilágyi; G Hegyi; K Pintér; Gábor Náray-Szabó; J Hepp; Katalin F Medzihradszky; W J Rutter
Electrostatic complementarity within the substrate-binding pocket of trypsin.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(14):4961-5.
1988: S R Sprang; Robert J Fletterick; László Gráf; W J Rutter; Charles S Craik
Studies of specificity and catalysis in trypsin by structural analysis of site-directed mutants.
Critical reviews in biotechnology 1988;8(3):225-36.
1987: A Páldi; M Móra; S Bajusz; László Gráf
Inhibition of angiotensin-converting enzyme by angiotensin I analogue peptide inhibitors. A kinetic study.
International journal of peptide and protein research 1987;29(6):746-54.
1987: László Gráf; Charles S Craik; A Patthy; S Roczniak; Robert J Fletterick; W J Rutter
Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin.
Biochemistry 1987;26(9):2616-23.
1987: D G Payan; K Horváth; László Gráf
Specific high-affinity binding sites for a synthetic gliadin heptapeptide on human peripheral blood lymphocytes.
Life sciences 1987;40(12):1229-36.
1987: László Gráf; K Horvath; E Walcz; I Berzetei; J Burnier
Effect of two synthetic alpha-gliadin peptides on lymphocytes in celiac disease: identification of a novel class of opioid receptors.
Neuropeptides 1987;9(2):113-22.
1987: A Kenessey; László Gráf; P Páldi-Haris; T Láng
Interaction of 2,3-benzodiazepines with peripheral benzodiazepine receptors.
Pharmacological research communications 1987;19(1):1-14.
1986: László Gráf; K Horváth; I Berzétei; F Antoni
[Gliadin and gliadophins: studies of structure and mechanism of action in lymphocytes in children with celiac disease].
Orvosi hetilap 1986;127(51):3105-10.
1986: K Horváth; László Gráf; E Walcz; H Bodánszky; G Horn
[Opioid activity of gliadin in the leukocyte migration inhibition test].
Orvosi hetilap 1986;127(6):317-9.
1985: K Horváth; László Gráf; E Walcz; H Bodánszky; Dezsõ Schuler
Naloxone antagonises effect of alpha-gliadin on leucocyte migration in patients with coeliac disease.
Lancet 1985;2(8448):184-5.
1985: Y Ebina; L Ellis; Kurt Jarnagin; M Edery; László Gráf; E Clauser; Jing-hsiung Ou; F Masiarz; Y W Kan; I D Goldfine
The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling.
Cell 1985;40(4):747-58.
1985: László Gráf; A Páldi; András Patthy
Action of neutral metalloendopeptidase ("enkephalinase") on beta-endorphin.
Neuropeptides 1985;6(1):13-9.
1985: P Páldi-Haris; László Gráf; A Kenessey; T Láng
Enhancement of low affinity [3H]GABA binding by diazepam and a new 2,3-benzodiazepine.
European journal of pharmacology 1985;109(2):305-6.
1984: A Simonyi; M I K Fekete; A Kenessey; P Páldi-Haris; László Gráf
Prolonged ACTH treatment increases trypsin-like and phenylethanolamine-N-methyltransferase (PNMT) activity in the adrenals.
European journal of pharmacology 1984;106(2):465-6.
1983: A Nagy; László Gráf; A Lajtha
Met-enkephalin binding to opiate receptors is not functionally coupled to biodegradation.
Life sciences 1983;33(9):835-40.
1982: N G Seidah; K L Hsi; M Chrétien; E Barat; A Patthy; László Gráf
The primary structure of human beta-lipotropin. Further peptide sequencing resolves the controversy and suggests the existence of only one human beta-lipotropin.
FEBS letters 1982;147(2):267-72.
1982: László Gráf; A Nagy; A Lajtha
Enkephalin-hydrolyzing peptidases of rat brain membranes: are they topographically/functionally coupled to opiate receptors?
Life sciences 1982;31(16-17):1861-5.
1982: I Barna; László Gráf; Gábor Makara; G Rappay
A serine-proteinase inhibitor (Boc-D-Phe-Pro-Arg-H) inhibits the secretion of adrenocorticotropin- and beta-endorphin-immunoreactive peptides in vitro.
Neuropeptides 1982;3(1):65-70.
1982: K S Hui; László Gráf; A Lajtha
beta-Endorphin inhibits met-enkephalin breakdown by a brain aminopeptidase: structure-activity relationships.
Biochemical and biophysical research communications 1982;105(4):1482-7.
1982: László Gráf; C H Li; Michael D Jibson
Human somatotropin. Selective removal with trypsin of residues 135-145 from the hormone molecule with no loss of biological activities.
The Journal of biological chemistry 1982;257(5):2365-9.
1982: C H Cheng; László Gráf; C H Li
Human somatotropin 61. A simple method to predict potential of somatotropin fragments for noncovalent recombination by radioreceptor assay.
International journal of peptide and protein research 1982;19(3):240-2.
1982: László Gráf
Studies on prolactin. 46. Preferential cleavage of the Arg125-Leu126 peptide bond of ovine hormone with immobilized trypsin.
International journal of peptide and protein research 1982;19(2):212-4.
1982: B Pethö; László Gráf; I Karczag; J Borvendég; István Bitter; I Barna; I Hermann; Judit Tolna; K Baraczka
beta-Endorphin administration to acute schizophrenic patients: a double blind study.
Annals of the New York Academy of Sciences 1982;398():460-9.
1981: László Gráf; C H Li; C H Cheng; Michael D Jibson
Two contiguous thrombin fragments of human somatotropin form a functionally active recombinant, but the two homologous fragments from sheep hormone do not.
Biochemistry 1981;20(25):7251-8.
1981: Pierre Nicolas; T A Bewley; László Gráf; C H Li
beta-Endorphin: demonstration of a tertiary structure in aqueous solution.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(12):7290-3.
1981: László Gráf; C H Li
Human somatotropin: covalent reconstitution of two polypeptide contiguous fragments with thrombin.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(10):6135-8.
1981: A Kenessey; T Láng; László Gráf
Demonstration of an endogenous, highly potent, noncompetitive protein inhibitor(s) of 3H-diazepam binding in bovine brain.
International journal of peptide and protein research 1981;18(1):103-6.
1981: B Pethö; László Gráf; I Karczag; István Bitter; Judit Tolna; K Baraczka; C H Li
beta-Endorphin and schizophrenia.
Lancet 1981;1(8213):212-3.
1980: B Pethö; László Gráf; I Karczag; J Borvendég; István Bitter; I Barna; I Hermann; Judit Tolna; K Baraczka
[Endogenous opiates and schizophrenia. Treatment of acute schizophrenic psychoses with beta-endorphin].
Orvosi hetilap 1980;121(38):2307-11.
1980: László Gráf; Miklós Hollósi; I Barna; I Hermann; J Borvendég; N Ling
Probing the biologically and immunologically active conformation of beta-endorphin: studies on C-terminal deletion analogs.
Biochemical and biophysical research communications 1980;95(4):1623-7.
1980: László Gráf; Miklós Hollósi
Substrate conformation directs selective enzymic cleavage of beta-lipotropin into beta-endorphin.
Biochemical and biophysical research communications 1980;93(4):1089-93.
1979: E Barát; A Patthy; László Gráf
Action of cathepsin D on human beta-lipotropin: a possible source of human "beta-melanotropin".
Proceedings of the National Academy of Sciences of the United States of America 1979;76(12):6120-3.
1979: László Gráf; E Miglécz; S Bajusz; J I Székely
Met-enkephalin attenuates morphine tolerance in rats.
European journal of pharmacology 1979;58(3):345-6.
1979: M Wollemann; A Szebeni; S Bajusz; László Gráf
Effect of Met-enkephalin and (D-Met2,Pro5)-enkephalinamide on the adenylate cyclase activity of rat brain.
Neurochemical research 1979;4(5):627-31.
1979: A Kenessey; P Páldi-Haris; Gábor Makara; László Gráf
Trypsin-like activity of rat anterior pituitary in relation to secretory activity.
Life sciences 1979;25(5):437-43.
1979: J I Székely; E Miglécz; Z Dunai-Kovács; I Tarnawa; András Z Rónai; László Gráf; S Bajusz
Attenuation of morphine tolerance and dependence by alpha-melanocyte stimulating hormone(alpha-MSH).
Life sciences 1979;24(21):1931-8.
1979: László Gráf; A Kenessey; A Patthy; A Grynbaum; N Marks; A Lajtha
Cathepsin D generates gamma-endorphin from beta-endorphin.
Archives of biochemistry and biophysics 1979;193(1):101-9.
1979: András Z Rónai; I Berzétei; J I Székely; László Gráf; S Bajusz
Kinetic studies in isolated organs: tools to design analgesic peptides and to analyze their receptor effects.
Pharmacology 1979;18(1):18-24.
1978: S Bajusz; A Patthy; A Kenessey; László Gráf; J I Székely; András Z Rónai
Is there correlation between analgesic potency and biodegradation of enkephalin analogs?
Biochemical and biophysical research communications 1978;84(4):1045-53.
1977: A Patthy; László Gráf; A Kenessey; J I Székely; S Bajusz
Effect of bacitracin on the biodegradation of beta-endorphin.
Biochemical and biophysical research communications 1977;79(1):254-9.
1977: László Gráf; G Cseh; E Barát; András Z Rónai; J I Székely; A Kenessey; S Bajusz
Structure-function relationships in lipotropins.
Annals of the New York Academy of Sciences 1977;297():63-83.
1977: László Gráf; A Kenessey; I Berzétei; András Z Rónai
Demonstration of beta-lipotropin activating enzyme in porcine pituitary.
Biochemical and biophysical research communications 1977;78(3):1114-23.
1977: A Kenessey; László Gráf
Regional distribution of beta-lipotropin converting enzymes in rat pituitary and brain.
Brain research bulletin 1977;2(4):247-50.
1977: J I Székely; András Z Rónai; Z Dunai-Kovács; E Miglécz; I Berzétri; S Bajusz; László Gráf
(D-met2, pro5)-enkephalinamide: a potent morphine-like analgesic.
European journal of pharmacology 1977;43(3):293-4.
1977: S Bajusz; András Z Rónai; J I Székely; László Gráf; Z Dunai-Kovács; I Berzétei
A superactive antinociceptive pentapeptide, (D-Met2, Pro5)-enkephalinamide.
FEBS letters 1977;76(1):91-2.
1977: J I Szkely; András Z Rónai; Z Dunai-Kovács; E Miglécz; S Bajusz; László Gráf
Cross tolerance between morphine and beta-endorphin in vivo.
Life sciences 1977;20(7):1259-64.
1977: András Z Rónai; László Gráf; I Székely; Z Dunai-Kovács; S Bajusz
Differential behaviour of LPH-(61-91)-peptide in different model systems: comparison of the opioid activities of LPH-(61-91)-peptide and its fragments.
FEBS letters 1977;74(2):182-4.
1977: M Hollósi; M Kajtár; László Gráf
Studies on the conformation of beta-endorphin and its constituent fragments in water and trifluorethanol by CD spectroscopy.
FEBS letters 1977;74(2):185-9.
1977: J I Székely; András Z Rónai; Z Dunai-Kovács; László Gráf; S Bajusz
C-terminal fragment (residues 61-91) of beta-lipotropin: is it the natural opiate-like neurohormon of the brain?
Experientia 1977;33(1):54-5.
1976: László Gráf; A Kenessey
Specific cleavage of a single peptide bond (residues 77-78) in beta-lipotropin by a pituitary endopeptidase.
FEBS letters 1976;69(1):255-60.
1976: László Gráf; J I Szekely; András Z Rónai; Z Dunai-Kovacs; S Bajusz
Comparative study on analgesic effect of Met5-enkephalin and related lipotropin fragments.
Nature 1976;263(5574):240-2.
1976: András Z Rónai; J I Székely; László Gráf; Z Dunai-Kovács; S Bajusz
Morphine-like analgesic effect of a pituitary hormone, beta-lipotropin.
Life sciences 1976;19(5):733-8.
1976: László Gráf; J Borvendég; E Barát; I Hermann; A Patthy
Reactivity and biological importance of the disulfide bonds in human growth hormone.
FEBS letters 1976;66(2):233-7.
1976: László Gráf; E Barát; J Borvendég; I Hermann; A Patthy
Action of thrombin on ovine, bovine and human pituitary growth hormones.
European journal of biochemistry / FEBS 1976;64(2):333-40.
1976: László Gráf; András Z Rónai; S Bajusz; G Csheh; J I Székely
Opioid agonist activity of beta-lipotropin fragments: a possible biological source of morphine-like substances in the pituitary.
FEBS letters 1976;64(1):181-4.
1976: S Bajusz; András Z Rónai; J I Székely; Z Dunai-Kovács; I Berzétei; László Gráf
Enkephalin analogs with enhanced opiate activity.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1976;11(4):305-9.
1976: D Bagdy; E Barabas; László Gráf; T E Petersen; S Magnusson
Hirudin.
Methods in enzymology 1976;45():669-78.
1976: László Gráf; E Barát; A Patthy
Isolation of a COOH-terminal beta-lipotropin fragment (residues 61--91) with morphine-like analgesic activity from porcine pituitary glands.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1976;11(2-3):121-2.
1976: László Gráf
Isolation and evolution of the gastrointestinal hormones.
Acta physiologica Academiae Scientiarum Hungaricae 1976;47(4):285-98.
1976: László Gráf
Chemistry of the lipotropins.
Pharmacology & therapeutics. Part B: General & systematic pharmacology 1976;2(4):753-69.
1976: László Gráf
Fragmentation of porcine beta-lipotropic hormone with plasmin.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1976;11(4):267-77.
1975: László Gráf; C H Li; T A Bewley
Selective reduction and alkylation of the COOH-terminal disulfide bridge in bovine growth hormone.
International journal of peptide and protein research 1975;7(6):467-73.
1974: László Gráf; C H Li
Isolation and properties of two biologically active fragments from limited tryptic hydrolysis of bovine and ovine pituitary growth hormones.
Biochemistry 1974;13(26):5408-15.
1974: László Gráf; C H Li
Action of plasmin on oxidized bovine growth hormone.
Archives of biochemistry and biophysics 1974;161(2):691-5.
1974: C H Li; László Gráf
Human pituitary growth hormone: isolation and properties of two biologically active fragments from plasmin digests.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(4):1197-201.
1974: László Gráf; C H Li
On the primary structure of pituitary bovine growth hormone.
Biochemical and biophysical research communications 1974;56(1):168-76.
1974: László Gráf; B Szalontai; E Barát; P Zăvodszky; J Borvendég; I Hermann; G Cseh
Studies on the multiplicity of polypeptide hormones. I. Isolation of human pituitary growth hormone and characterization of the aggregates.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1974;9(4):309-17.
1973: László Gráf; C H Li
Action of plasmin on ovine beta-lipotropin: revision of the carboxyl terminal sequence.
Biochemical and biophysical research communications 1973;53(4):1304-9.
1973: László Gráf; A Patthy; E B Barabás; D Bagdy
On the NH 2 -terminal residue of hirudin.
Biochimica et biophysica acta 1973;310(2):416-7.
1973: László Gráf; G Hajós; A Patthy; G Cseh
The influence of deamidation on the biological activity of porcine adrenocorticotropic hormone (ACTH).
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1973;5(2):142-3.
1973: G Cseh; László Gráf; C Sutka
Relationship between primary structure and lipolysis stimulating activity of beta-lipotropic hormone.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1973;8(4):245-51.
1972: László Gráf
Re-examination of the sequence of the C-terminal tryptic fragment from porcine adrenocorticotropic hormone.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1972;7(4):293-7.
1971: C Sajgó; László Gráf; E Barát; M Sajgó
Amino acid sequence of porcine beta-lipotropic hormone.
Biochimica et biophysica acta 1971;229(1):276-8.
1971: László Gráf; S Bajusz; A Patthy; E Barát; G Cseh
Revised amide location for porcine and human adrenocorticotropic hormone.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1971;6(4):415-8.
1970: László Gráf; E Barát; G Cseh; M Sajgó
Amino acid sequence of porcine gamma-lipotropic hormone.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1970;5(3):305-7.
1970: László Gráf; G Cseh; I Nagy; M Kurcz
An evidence for deamidation of prolactin monomer.
Acta biochimica et biophysica; Academiae Scientiarum Hungaricae 1970;5(3):299-303.
1969: G Cseh; J Fövényi; E Góth; László Gráf; G Tamási
[Demonstration of lipotropic hormone (beta-lipotropin) in human hypophysis (preliminary report)].
Orvosi hetilap 1969;110(27):1546-7.
1969: G Tamási; G Cseh; László Gráf
Effects of porcine beta-lipotropic hormone on lipid metabolism.
Experientia 1969;25(4):360-1.
1969: László Gráf; G Cseh
Isolation of gamma-lipotropic hormone from porcine pituitary glands.
Biochimica et biophysica acta 1969;175(2):444-7.