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Chris Grant

Research Profile

Anatomy

Lipid Bilayers

Chemicals & Drugs

Phenomena

Magnetic Resonance Spectroscopy

Concepts & Ideas

Procedures

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Membrane Fluidity

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Publications

TOP 3
David J Goodyear; Simon Sharpe; Chris W M Grant; Michael R Morrow
Molecular dynamics simulation of transmembrane polypeptide orientational fluctuations.
Simon Sharpe; Kathryn R Barber; Chris W M Grant; David Goodyear; Michael R Morrow
Organization of model helical peptides in lipid bilayers: insight into the behavior of single-span protein transmembrane domains.
Simon Sharpe; Kathryn R Barber; Chris W M Grant
Interaction between ErbB-1 and ErbB-2 transmembrane domains in bilayer membranes.

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All Publications

2005: David J Goodyear; Simon Sharpe; Chris W M Grant; Michael R Morrow
Molecular dynamics simulation of transmembrane polypeptide orientational fluctuations.
Biophysical journal 2005;88(1):105-17.
2002: Simon Sharpe; Kathryn R Barber; Chris W M Grant; David Goodyear; Michael R Morrow
Organization of model helical peptides in lipid bilayers: insight into the behavior of single-span protein transmembrane domains.
Biophysical journal 2002;83(1):345-58.
2002: Simon Sharpe; Kathryn R Barber; Chris W M Grant
Interaction between ErbB-1 and ErbB-2 transmembrane domains in bilayer membranes.
FEBS letters 2002;519(1-3):103-7.
2002: Simon Sharpe; Kathryn R Barber; Chris W M Grant
Evidence of a tendency to self-association of the transmembrane domain of ErbB-2 in fluid phospholipid bilayers.
Biochemistry 2002;41(7):2341-52.
2001: Simon Sharpe; Chris W M Grant; Kathryn R Barber; J Giusti; Michael R Morrow
Structural implications of a Val-->Glu mutation in transmembrane peptides from the EGF receptor.
Biophysical journal 2001;81(6):3231-9.
2000: Michael R Morrow; Chris W M Grant
The EGF receptor transmembrane domain: peptide-peptide interactions in fluid bilayer membranes.
Biophysical journal 2000;79(4):2024-32.
2000: Simon Sharpe; Chris W M Grant
A transmembrane peptide from the human EGF receptor: behaviour of the cytoplasmic juxtamembrane domain in lipid bilayers.
Biochimica et biophysica acta 2000;1468(1-2):262-72.
2000: Simon Sharpe; Kathryn R Barber; Chris W M Grant
Val(659)-->Glu mutation within the transmembrane domain of ErbB-2: effects measured by (2)H NMR in fluid phospholipid bilayers.
Biochemistry 2000;39(21):6572-80.
2000: DH Jones; Eric H Ball; Simon Sharpe; Kathryn R Barber; Chris W M Grant
Expression and membrane assembly of a transmembrane region from Neu.
Biochemistry 2000;39(7):1870-8.
1998: DH Jones; Kathryn R Barber; E W VanDerLoo; Chris W M Grant
Epidermal growth factor receptor transmembrane domain: 2H NMR implications for orientation and motion in a bilayer environment.
Biochemistry 1998;37(47):16780-7.
1998: Alan Rigby; Chris W M Grant; Gary Shaw
Solution and solid state conformation of the human EGF receptor transmembrane region.
Biochimica et biophysica acta 1998;1371(2):241-53.
1998: DH Jones; Kathryn R Barber; Chris W M Grant
Sequence-related behaviour of transmembrane domains from class I receptor tyrosine kinases.
Biochimica et biophysica acta 1998;1371(2):199-212.
1998: DH Jones; Kathryn R Barber; Chris W M Grant
The EGF receptor transmembrane domain: 2H NMR study of peptide phosphorylation effects in a bilayer environment.
Biochemistry 1998;37(20):7504-8.
1997: DH Jones; R S Hodges; Kathryn R Barber; Chris W M Grant
Pilin C-terminal peptide binds asialo-GM1 in liposomes: a 2H-NMR study.
Protein science : a publication of the Protein Society 1997;6(11):2459-61.
1997: DH Jones; Alan Rigby; Kathryn R Barber; Chris W M Grant
Oligomerization of the EGF receptor transmembrane domain: a 2H NMR study in lipid bilayers.
Biochemistry 1997;36(41):12616-24.
1997: DH Jones; C A Lingwood; Kathryn R Barber; Chris W M Grant
Globoside as a membrane receptor: a consideration of oligosaccharide communication with the hydrophobic domain.
Biochemistry 1997;36(28):8539-47.
1996: Alan Rigby; Kathryn R Barber; Chris W M Grant
Sphingolipid-derived signalling modulators: interaction with phosphatidylserine.
Biochimica et biophysica acta 1996;1284(2):129-33.
1996: Alan Rigby; Kathryn R Barber; Gary Shaw; Chris W M Grant
Transmembrane region of the epidermal growth factor receptor: behavior and interactions via 2H NMR.
Biochemistry 1996;35(38):12591-601.
1996: DH Jones; Kathryn R Barber; Chris W M Grant
Minor influence of sialic acid on conformation of a membrane-bound oligosaccharide recognition site.
Biochemistry 1996;35(15):4803-11.
1995: Alan Rigby; Kathryn R Barber; Chris W M Grant
2H-NMR study of two probe-labelled glycosphingolipid-derived signalling modulators in bilayer membranes.
Biochimica et biophysica acta 1995;1240(1):75-82.
1995: Michael R Morrow; D M Singh; Chris W M Grant
Glycosphingolipid headgroup orientation in fluid phospholipid/cholesterol membranes: similarity for a range of glycolipid fatty acids.
Biophysical journal 1995;69(3):955-64.
1995: Michael R Morrow; D Singh; Chris W M Grant
Glycosphingolipid acyl chain order profiles: substituent effects.
Biochimica et biophysica acta 1995;1235(2):239-48.
1995: D M Singh; X Shan; J H Davis; DH Jones; Chris W M Grant
Oligosaccharide behavior of complex natural glycosphingolipids in multicomponent model membranes.
Biochemistry 1995;34(2):451-63.
1995: Michael R Morrow; D Singh; D Lu; Chris W M Grant
Glycosphingolipid fatty acid arrangement in phospholipid bilayers: cholesterol effects.
Biophysical journal 1995;68(1):179-86.
1994: Kathryn R Barber; K S Hamilton; Alan Rigby; Chris W M Grant
Behaviour of complex oligosaccharides at a bilayer membrane surface: probed by 2H-NMR.
Biochimica et biophysica acta 1994;1190(2):376-84.
1994: K S Hamilton; K Briere; Harold C Jarrell; Chris W M Grant
Acyl chain length effects related to glycosphingolipid crypticity in phospholipid membranes: probed by 2H-NMR.
Biochimica et biophysica acta 1994;1190(2):367-75.
1993: K S Hamilton; Harold C Jarrell; K M Brière; Chris W M Grant
Glycosphingolipid backbone conformation and behavior in cholesterol-containing phospholipid bilayers.
Biochemistry 1993;32(15):4022-8.
1993: Michael R Morrow; D Singh; D Lu; Chris W M Grant
Glycosphingolipid acyl chain orientational order in unsaturated phosphatidylcholine bilayers.
Biophysical journal 1993;64(3):654-64.
1993: D Lu; D Singh; Michael R Morrow; Chris W M Grant
Effect of glycosphingolipid fatty acid chain length on behavior in unsaturated phosphatidylcholine bilayers: a 2H NMR study.
Biochemistry 1993;32(1):290-7.
1993: R T Stavraky; Chris W M Grant; Kathryn R Barber; Stephen J Karlik
Baseline consideration of liposomal contrast agent. CNS transport by macrophages in experimental allergic encephalomyelitis.
Magnetic resonance imaging 1993;11(5):685-9.
1992: D Singh; J H Davis; Chris W M Grant
Behaviour of a glycosphingolipid with unsaturated fatty acid in phosphatidylcholine bilayers.
Biochimica et biophysica acta 1992;1107(1):23-30.
1992: Michael R Morrow; D Singh; D Lu; Chris W M Grant
Glycosphingolipid phase behaviour in unsaturated phosphatidylcholine bilayers: a 2H-NMR study.
Biochimica et biophysica acta 1992;1106(1):85-93.
1992: D Singh; Harold C Jarrell; Kathryn R Barber; Chris W M Grant
Glycosphingolipids: 2H NMR study of the influence of ceramide fatty acid characteristics on the carbohydrate headgroup in phospholipid bilayers.
Biochemistry 1992;31(10):2662-9.
1992: Harold C Jarrell; D Singh; Chris W M Grant
Oligosaccharide order in a membrane-incorporated complex glycosphingolipid.
Biochimica et biophysica acta 1992;1103(2):331-4.
1992: D Singh; Harold C Jarrell; E Florio; D B Fenske; Chris W M Grant
Effects of fatty acid alpha-hydroxylation on glycosphingolipid properties in phosphatidylcholine bilayers.
Biochimica et biophysica acta 1992;1103(2):268-74.
1991: Paul C Adams; E Lin; Kathryn R Barber; Chris W M Grant
Enhanced biliary iron excretion with amphiphilic diethylenetriaminepentaacetic acid.
Hepatology (Baltimore, Md.) 1991;14(6):1230-4.
1991: D B Fenske; K Hamilton; Harold C Jarrell; E Florio; Kathryn R Barber; Chris W M Grant
Glycosphingolipids: 2H NMR study of the influence of carbohydrate headgroup structure on ceramide acyl chain behavior in glycolipid-phospholipid bilayers.
Biochemistry 1991;30(18):4503-9.
1991: Stephen J Karlik; E Florio; Chris W M Grant
Comparative evaluation of two membrane-based liposomal MRI contrast agents.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;19(1):56-66.
1991: K S Hamilton; Kathryn R Barber; J H Davis; K Neil; Chris W M Grant
Phase behaviour of amphotericin B multilamellar vesicles.
Biochimica et biophysica acta 1991;1062(2):220-6.
1991: Edward Ralph; Kathryn R Barber; Chris W M Grant
Liposomal amphotericin B: an effective, nontoxic preparation for the treatment of urinary tract infections caused by Candida albicans.
American journal of nephrology 1991;11(2):118-22.
1990: Chris W M Grant; Harold C Jarrell; E Florio
Glycosphingolipid arrangement and dynamics in membranes.
Biochemical Society transactions 1990;18(5):827-31.
1990: E Florio; Harold C Jarrell; D B Fenske; Kathryn R Barber; Chris W M Grant
Glycosphingolipid interdigitation in phospholipid bilayers examined by deuterium NMR and EPR.
Biochimica et biophysica acta 1990;1025(2):157-63.
1989: Chris W M Grant; K S Hamilton; K D Hamilton; Kathryn R Barber
Physical biochemistry of a liposomal amphotericin B mixture used for patient treatment.
Biochimica et biophysica acta 1989;984(1):11-20.
1989: Chris W M Grant; Stephen J Karlik; E Florio
A liposomal MRI contrast agent: phosphatidylethanolamine-DTPA.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1989;11(2):236-43.
1988: I E Mehlhorn; Kathryn R Barber; Chris W M Grant
Globoside with spin-labelled fatty acid: bilayer lateral distribution and immune recognition.
Biochimica et biophysica acta 1988;943(3):389-404.
1988: I E Mehlhorn; E Florio; Kathryn R Barber; C Lordo; Chris W M Grant
Evidence that trans-bilayer interdigitation of glycosphingolipid long chain fatty acids may be a general phenomenon.
Biochimica et biophysica acta 1988;939(1):151-9.
1987: Chris W M Grant; Kathryn R Barber; E Florio; Stephen J Karlik
A phospholipid spin label used as a liposome-associated MRI contrast agent.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1987;5(4):371-6.
1987: Kathryn R Barber; I E Mehlhorn; Chris W M Grant
Double label freeze-etch study of the relative topography of concanavalin A and wheat germ agglutinin receptors at the myoblast surface.
Biochimica et biophysica acta 1987;902(3):395-401.
1987: Chris W M Grant; I E Mehlhorn; E Florio; Kathryn R Barber
A long chain spin label for glycosphingolipid studies: transbilayer fatty acid interdigitation of lactosyl ceramide.
Biochimica et biophysica acta 1987;902(2):169-77.
1987: Rudy L Juliano; Chris W M Grant; Kathryn R Barber; M A Kalp
Mechanism of the selective toxicity of amphotericin B incorporated into liposomes.
Molecular pharmacology 1987;31(1):1-11.
1986: I E Mehlhorn; G Parraga; Kathryn R Barber; Chris W M Grant
Visualization of domains in rigid ganglioside/phosphatidylcholine bilayers: Ca2+ effects.
Biochimica et biophysica acta 1986;863(2):139-55.
1986: Kathryn R Barber; I E Mehlhorn; G Párraga; Chris W M Grant
Freeze-etch visualization of the outer surface of myoblasts in culture.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1986;64(3):194-204.
1984: M W Peters; I E Mehlhorn; Kathryn R Barber; Chris W M Grant
Evidence of a distribution difference between two gangliosides in bilayer membranes.
Biochimica et biophysica acta 1984;778(3):419-28.
1984: Chris W M Grant; M W Peters
Lectin-membrane interactions. Information from model systems.
Biochimica et biophysica acta 1984;779(4):403-22.
1984: M W Peters; Chris W M Grant
Freeze-etch study of an unmodified lectin interacting with its receptors in model membranes.
Biochimica et biophysica acta 1984;775(3):273-82.
1984: M W Peters; Kathryn R Barber; Chris W M Grant
Lateral distribution of gangliosides in bilayer membranes: lipid and ionic effects.
Journal of neuroscience research 1984;12(2-3):343-53.
1984: M W Peters; Chris W M Grant
Physical behaviour of glycolipids in bilayer membranes: distribution and accessibility.
Advances in experimental medicine and biology 1984;174():119-31.
1983: M W Peters; C Singleton; Kathryn R Barber; Chris W M Grant
Glycolipid crypticity in membranes--not a simple shielding effect of macromolecules.
Biochimica et biophysica acta 1983;731(3):475-82.
1983: N V Ketis; Chris W M Grant
Time-dependent lectin binding to isolated receptors in model membranes.
Biochimica et biophysica acta 1983;730(2):359-68.
1982: M W Peters; Kathryn R Barber; Chris W M Grant
Headgroup behaviour of an uncharged complex glycolipid.
Biochimica et biophysica acta 1982;693(2):417-24.
1982: N V Ketis; Chris W M Grant
Control of high affinity lectin binding to an integral membrane glycoprotein in lipid bilayers.
Biochimica et biophysica acta 1982;685(3):347-54.
1980: P M Lee; Chris W M Grant
Headgroup oligosaccharide dynamics of a transmembrane glycoprotein.
Canadian journal of biochemistry 1980;58(10):1197-205.
1980: P M Lee; N V Ketis; Kathryn R Barber; Chris W M Grant
Ganglioside headgroup dynamics.
Biochimica et biophysica acta 1980;601(2):302-14.
1980: P M Lee; Chris W M Grant
Ganglioside headgroup disorder as a sequel to lectin binding.
Biochemical and biophysical research communications 1980;95(3):1299-305.
1980: N V Ketis; J Girdlestone; Chris W M Grant
Positive cooperativity in a (dissected) lectin-membrane glycoprotein binding event.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(7):3788-90.