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Henk Granzier

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Chandra Murali; Mamidi Ranganath; Ford Steven; Hidalgo Carlos; Witt Christian; Ottenheijm Coen; Labeit Siegfried; Granzier Henk
Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost.
Ottenheijm Coen A C; Knottnerus Anna M; Buck Danielle; Luo Xiuju; Greer Kevin; Hoying Adam; Labeit Siegfried; Granzier Henk
Tuning passive mechanics through differential splicing of titin during skeletal muscle development.
Ottenheijm Coen A C; Hidalgo Carlos; Rost Katharina; Gotthardt Michael; Granzier Henk
Altered contractility of skeletal muscle in mice deficient in titin's M-band region.

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All Publications

2009: Chandra Murali; Mamidi Ranganath; Ford Steven; Hidalgo Carlos; Witt Christian; Ottenheijm Coen; Labeit Siegfried; Granzier Henk
Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost.
The Journal of biological chemistry 2009;284(45):30889-96.
2009: Ottenheijm Coen A C; Knottnerus Anna M; Buck Danielle; Luo Xiuju; Greer Kevin; Hoying Adam; Labeit Siegfried; Granzier Henk
Tuning passive mechanics through differential splicing of titin during skeletal muscle development.
Biophysical journal 2009;97(8):2277-86.
2009: Ottenheijm Coen A C; Hidalgo Carlos; Rost Katharina; Gotthardt Michael; Granzier Henk
Altered contractility of skeletal muscle in mice deficient in titin's M-band region.
Journal of molecular biology 2009;393(1):10-26.
2009: Hidalgo Carlos; Hudson Bryan; Bogomolovas Julius; Zhu Yi; Anderson Brian; Greaser Marion; Labeit Siegfried; Granzier Henk
PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness.
Circulation research 2009;105(7):631-8, 17 p following 638.
2009: Granzier Henk L; Radke Michael H; Peng Jun; Westermann Dirk; Nelson O Lynne; Rost Katharina; King Nicholas M P; Yu Qianli; Tschöpe Carsten; McNabb Mark; Larson Douglas F; Labeit Siegfried; Gotthardt Michael
Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.
Circulation research 2009;105(6):557-64.
2009: Gramlich Michael; Michely Beate; Krohne Christian; Heuser Arnd; Erdmann Bettina; Klaassen Sabine; Hudson Bryan; Magarin Manuela; Kirchner Florian; Todiras Mihail; Granzier Henk; Labeit Siegfried; Thierfelder Ludwig; Gerull Brenda
Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease.
Journal of molecular and cellular cardiology 2009;47(3):352-8.
2009: Williams Lynne; Howell Neil; Pagano Domenico; Andreka Peter; Vertesaljai Marton; Pecor Tiffany; Frenneaux Michael; Granzier Henk
Titin isoform expression in aortic stenosis.
Clinical science (London, England : 1979) 2009;117(6):237-42.
2009: Ottenheijm Coen A C; Witt Christian C; Stienen Ger J; Labeit Siegfried; Beggs Alan H; Granzier Henk
Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency.
Human molecular genetics 2009;18(13):2359-69.
2009: Zhu Yi; Bogomolovas Julius; Labeit Siegfried; Granzier Henk
Single molecule force spectroscopy of the cardiac titin N2B element: effects of the molecular chaperone alphaB-crystallin with disease-causing mutations.
The Journal of biological chemistry 2009;284(20):13914-23.
2008: Kramerova Irina; Kudryashova Elena; Wu Benjamin; Ottenheijm Coen; Granzier Henk; Spencer Melissa J
Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle.
Human molecular genetics 2008;17(21):3271-80.
2008: Ottenheijm Coen A C; Fong Chi; Vangheluwe Peter; Wuytack Frank; Babu Gopal J; Periasamy Muthu; Witt Christian C; Labeit Siegfried; Granzier Henk
Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(8):2912-9.
2008: Nelson O Lynne; Robbins Charles T; Wu Yiming; Granzier Henk
Titin isoform switching is a major cardiac adaptive response in hibernating grizzly bears.
American journal of physiology. Heart and circulatory physiology 2008;295(1):H366-71.
2007: Granzier Henk; Labeit Siegfried
Structure-function relations of the giant elastic protein titin in striated and smooth muscle cells.
Muscle & nerve 2007;36(6):740-55.
2007: Granzier Henk; Radke Michael; Royal Joseph; Wu Yiming; Irving Thomas C; Gotthardt Michael; Labeit Siegfried
Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(2):R557-67.
2007: Takata Hideaki; Uchiyama Susumu; Nakamura Naoko; Nakashima Shoko; Kobayashi Shouhei; Sone Takefumi; Kimura Sumiko; Lahmers Sunshine; Granzier Henk; Labeit Siegfried; Matsunaga Sachihiro; Fukui Kiichi
A comparative proteome analysis of human metaphase chromosomes isolated from two different cell lines reveals a set of conserved chromosome-associated proteins.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(3):269-84.
2007: Radke Michael H; Peng Jun; Wu Yiming; McNabb Mark; Nelson O Lynne; Granzier Henk; Gotthardt Michael
Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3444-9.
2007: Peng Jun; Raddatz Katy; Molkentin Jeffery D; Wu Yiming; Labeit Siegfried; Granzier Henk; Gotthardt Michael
Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region.
Circulation 2007;115(6):743-51.
2007: Wu Yiming; Peng Jun; Campbell Kenneth B; Labeit Siegfried; Granzier Henk
Hypothyroidism leads to increased collagen-based stiffness and re-expression of large cardiac titin isoforms with high compliance.
Journal of molecular and cellular cardiology 2007;42(1):186-95.
2007: LeWinter Martin M; Wu Yiming; Labeit Siegfried; Granzier Henk
Cardiac titin: structure, functions and role in disease.
Clinica chimica acta; international journal of clinical chemistry 2007;375(1-2):1-9.
2006: Hidalgo Carlos; Wu Yiming; Peng Jun; Siems William F; Campbell Kenneth B; Granzier Henk
Effect of diastolic pressure on MLC2v phosphorylation in the rat left ventricle.
Archives of biochemistry and biophysics 2006;456(2):216-23.
2006: Granzier Henk L; Campbell Kenneth B
New insights in the role of cardiac myosin binding protein C as a regulator of cardiac contractility.
Circulation research 2006;99(8):795-7.
2006: Labeit Siegfried; Lahmers Sunshine; Burkart Christoph; Fong Chi; McNabb Mark; Witt Stephanie; Witt Christian; Labeit Dietmar; Granzier Henk
Expression of distinct classes of titin isoforms in striated and smooth muscles by alternative splicing, and their conserved interaction with filamins.
Journal of molecular biology 2006;362(4):664-81.
2006: Witt Christian C; Burkart Christoph; Labeit Dietmar; McNabb Mark; Wu Yiming; Granzier Henk; Labeit Siegfried
Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo.
The EMBO journal 2006;25(16):3843-55.
2006: Gerull Brenda; Atherton John; Geupel Anke; Sasse-Klaassen Sabine; Heuser Arnd; Frenneaux Michael; McNabb Mark; Granzier Henk; Labeit Siegfried; Thierfelder Ludwig
Identification of a novel frameshift mutation in the giant muscle filament titin in a large Australian family with dilated cardiomyopathy.
Journal of molecular medicine (Berlin, Germany) 2006;84(6):478-83.
2006: Granzier Henk L; Labeit Siegfried
The giant muscle protein titin is an adjustable molecular spring.
Exercise and sport sciences reviews 2006;34(2):50-3.
2006: Ottenheijm Coen A C; Heunks Leo M A; Hafmans Theo; van der Ven Peter F M; Benoist Caroline; Zhou Honghui; Labeit Siegfried; Granzier Henk L; Dekhuijzen P N Richard
Titin and diaphragm dysfunction in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2006;173(5):527-34.
2005: Granzier Henk; Wu Yiming; Siegfried Labeit; LeWinter Martin
Titin: physiological function and role in cardiomyopathy and failure.
Heart failure reviews 2005;10(3):211-23.
2005: Witt Stephanie H; Granzier Henk; Witt Christian C; Labeit Siegfried
MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination.
Journal of molecular biology 2005;350(4):713-22.
2005: Campbell K B; Wu Y; Simpson A M; Kirkpatrick R D; Shroff S G; Granzier H L; Slinker B K
Dynamic myocardial contractile parameters from left ventricular pressure-volume measurements.
American journal of physiology. Heart and circulatory physiology 2005;289(1):H114-30.
2005: Nagy A; Grama L; Huber T; Bianco P; Trombitás K; Granzier H L; Kellermayer M S Z
Hierarchical extensibility in the PEVK domain of skeletal-muscle titin.
Biophysical journal 2005;89(1):329-36.
2005: Fukuda Norio; Wu Yiming; Nair Preetha; Granzier Henk L
Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner.
The Journal of general physiology 2005;125(3):257-71.
2005: Fukuda Norio; Wu Yiming; Farman Gerrie; Irving Thomas C; Granzier Henk
Titin-based modulation of active tension and interfilament lattice spacing in skinned rat cardiac muscle.
Pflügers Archiv : European journal of physiology 2005;449(5):449-57.
2005: Peng J; Raddatz K; Labeit S; Granzier H; Gotthardt M
Muscle atrophy in titin M-line deficient mice.
Journal of muscle research and cell motility 2005;26(6-8):381-8.
2005: Preetha Nair; Yiming Wu; Helmes Michiel; Norio Fukuda; Siegfried Labeit; Granzier Henk
Restoring force development by titin/connectin and assessment of Ig domain unfolding.
Journal of muscle research and cell motility 2005;26(6-8):307-17.
2005: Fukuda Norio; Granzier Henk L
Titin/connectin-based modulation of the Frank-Starling mechanism of the heart.
Journal of muscle research and cell motility 2005;26(6-8):319-23.
2005: Witt Stephanie H; Labeit Dietmar; Granzier Henk; Labeit Siegfried; Witt Christian C
Dimerization of the cardiac ankyrin protein CARP: implications for MARP titin-based signaling.
Journal of muscle research and cell motility 2005;26(6-8):401-8.
2005: Granzier Henk L; Labeit Siegfried
Titin and its associated proteins: the third myofilament system of the sarcomere.
Advances in protein chemistry 2005;71():89-119.
2004: Fujita Hideaki; Labeit Dietmar; Gerull Brenda; Labeit Siegfried; Granzier Henk L
Titin isoform-dependent effect of calcium on passive myocardial tension.
American journal of physiology. Heart and circulatory physiology 2004;287(6):H2528-34.
2004: Wu Yiming; Tobias Anthony H; Bell Kenneth; Barry William; Helmes Michiel; Trombitas Karoly; Tucker Russell; Campbell Kenneth B; Granzier Henk L
Cellular and molecular mechanisms of systolic and diastolic dysfunction in an avian model of dilated cardiomyopathy.
Journal of molecular and cellular cardiology 2004;37(1):111-9.
2004: Nagueh Sherif F; Shah Gopi; Wu Yiming; Torre-Amione Guillermo; King Nicholas M P; Lahmers Sunshine; Witt Christian C; Becker Katy; Labeit Siegfried; Granzier Henk L
Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy.
Circulation 2004;110(2):155-62.
2004: Fukuda Norio; Granzier Henk
Role of the giant elastic protein titin in the Frank-Starling mechanism of the heart.
Current vascular pharmacology 2004;2(2):135-9.
2004: Miller Melanie K; Granzier Henk; Ehler Elisabeth; Gregorio Carol C
The sensitive giant: the role of titin-based stretch sensing complexes in the heart.
Trends in cell biology 2004;14(3):119-26.
2004: Lahmers Sunshine; Wu Yiming; Call Douglas R; Labeit Siegfried; Granzier Henk
Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium.
Circulation research 2004;94(4):505-13.
2004: Granzier Henk L; Labeit Siegfried
The giant protein titin: a major player in myocardial mechanics, signaling, and disease.
Circulation research 2004;94(3):284-95.
2004: Witt Christian C; Ono Yasuko; Puschmann Eva; McNabb Mark; Wu Yiming; Gotthardt Michael; Witt Stephanie H; Haak Markus; Labeit Dietmar; Gregorio Carol C; Sorimachi Hiroyuki; Granzier Henk; Labeit Siegfried
Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling.
Journal of molecular biology 2004;336(1):145-54.
2003: Labeit Dietmar; Watanabe Kaori; Witt Christian; Fujita Hideaki; Wu Yiming; Lahmers Sunshine; Funck Theodor; Labeit Siegfried; Granzier Henk
Calcium-dependent molecular spring elements in the giant protein titin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13716-21.
2003: Miller Melanie K; Bang Marie-Louise; Witt Christian C; Labeit Dietmar; Trombitas Charles; Watanabe Kaori; Granzier Henk; McElhinny Abigail S; Gregorio Carol C; Labeit Siegfried
The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules.
Journal of molecular biology 2003;333(5):951-64.
2003: Trombitás K; Wu Y; McNabb M; Greaser M; Kellermayer M S Z; Labeit S; Granzier H
Molecular basis of passive stress relaxation in human soleus fibers: assessment of the role of immunoglobulin-like domain unfolding.
Biophysical journal 2003;85(5):3142-53.
2003: Fukuda Norio; Wu Yiming; Farman Gerrie; Irving Thomas C; Granzier Henk
Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle.
The Journal of physiology 2003;553(Pt 1):147-54.
2003: Granzier Henk L; Wu Yiming; Trombitas Karoly; Witt Christian; Labeit Siegfried; Bell Stephen; LeWinter Martin
Variable titin-based stiffness adjustment in heart disease.
Circulation 2003;108(4):e23.
2003: Kellermayer Miklós S Z; Bustamante Carlos; Granzier Henk L
Mechanics and structure of titin oligomers explored with atomic force microscopy.
Biochimica et biophysica acta 2003;1604(2):105-14.
2003: Gotthardt Michael; Hammer Robert E; Hübner Norbert; Monti Jan; Witt Christian C; McNabb Mark; Richardson James A; Granzier Henk; Labeit Siegfried; Herz Joachim
Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure.
The Journal of biological chemistry 2003;278(8):6059-65.
2003: Granzier Henk; Labeit Dietmar; Wu Yiming; Witt Christian; Watanabe Kaori; Lahmers Sunshine; Gotthardt Michael; Labeit Siegfried
Adaptations in titin's spring elements in normal and cardiomyopathic hearts.
Advances in experimental medicine and biology 2003;538():517-30; discussion 530-1.
2002: Wu Yiming; Labeit Siegfried; Lewinter Martin M; Granzier Henk
Titin: an endosarcomeric protein that modulates myocardial stiffness in DCM.
Journal of cardiac failure 2002;8(6 Suppl):S276-86.
2002: Wu Yiming; Bell Stephen P; Trombitas Karoly; Witt Christian C; Labeit Siegfried; LeWinter Martin M; Granzier Henk
Changes in titin isoform expression in pacing-induced cardiac failure give rise to increased passive muscle stiffness.
Circulation 2002;106(11):1384-9.
2002: Yamasaki R; Wu Y; McNabb M; Greaser M; Labeit S; Granzier H
Protein kinase A phosphorylates titin's cardiac-specific N2B domain and reduces passive tension in rat cardiac myocytes.
Circulation research 2002;90(11):1181-8.
2002: Granzier Henk; Labeit Siegfried
Cardiac titin: an adjustable multi-functional spring.
The Journal of physiology 2002;541(Pt 2):335-42.
2002: Toursel Thierry; Stevens Laurence; Granzier Henk; Mounier Yvonne
Passive tension of rat skeletal soleus muscle fibers: effects of unloading conditions.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(4):1465-72.
2002: Watanabe Kaori; Nair Preetha; Labeit Dietmar; Kellermayer Miklós S Z; Greaser Marion; Labeit Siegfried; Granzier Henk
Molecular mechanics of cardiac titin's PEVK and N2B spring elements.
The Journal of biological chemistry 2002;277(13):11549-58.
2002: Gerull Brenda; Gramlich Michael; Atherton John; McNabb Mark; Trombitás Karoly; Sasse-Klaassen Sabine; Seidman J G; Seidman Christine; Granzier Henk; Labeit Siegfried; Frenneaux Michael; Thierfelder Ludwig
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.
Nature genetics 2002;30(2):201-4.
2002: Watanabe Kaori; Muhle-Goll Claudia; Kellermayer Miklós S Z; Labeit Siegfried; Granzier Henk
Different molecular mechanics displayed by titin's constitutively and differentially expressed tandem Ig segments.
Journal of structural biology 2002;137(1-2):248-58.
2002: Granzier Henk; Labeit Dietmar; Wu Yiming; Labeit Siegfried
Titin as a modular spring: emerging mechanisms for elasticity control by titin in cardiac physiology and pathophysiology.
Journal of muscle research and cell motility 2002;23(5-6):457-71.
2001: Bang M L; Centner T; Fornoff F; Geach A J; Gotthardt M; McNabb M; Witt C C; Labeit D; Gregorio C C; Granzier H; Labeit S
The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system.
Circulation research 2001;89(11):1065-72.
2001: Muhle-Goll C; Habeck M; Cazorla O; Nilges M; Labeit S; Granzier H
Structural and functional studies of titin's fn3 modules reveal conserved surface patterns and binding to myosin S1--a possible role in the Frank-Starling mechanism of the heart.
Journal of molecular biology 2001;313(2):431-47.
2001: Yamasaki R; Berri M; Wu Y; Trombitás K; McNabb M; Kellermayer M S; Witt C; Labeit D; Labeit S; Greaser M; Granzier H
Titin-actin interaction in mouse myocardium: passive tension modulation and its regulation by calcium/S100A1.
Biophysical journal 2001;81(4):2297-313.
2001: Trombitás K; Wu Y; Labeit D; Labeit S; Granzier H
Cardiac titin isoforms are coexpressed in the half-sarcomere and extend independently.
American journal of physiology. Heart and circulatory physiology 2001;281(4):H1793-9.
2001: Cazorla O; Wu Y; Irving T C; Granzier H
Titin-based modulation of calcium sensitivity of active tension in mouse skinned cardiac myocytes.
Circulation research 2001;88(10):1028-35.
2001: Bang M L; Mudry R E; McElhinny A S; Trombitás K; Geach A J; Yamasaki R; Sorimachi H; Granzier H; Gregorio C C; Labeit S
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.
The Journal of cell biology 2001;153(2):413-27.
2001: Centner T; Yano J; Kimura E; McElhinny A S; Pelin K; Witt C C; Bang M L; Trombitas K; Granzier H; Gregorio C C; Sorimachi H; Labeit S
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.
Journal of molecular biology 2001;306(4):717-26.
2001: Kellermayer M S; Smith S B; Bustamante C; Granzier H L
Mechanical fatigue in repetitively stretched single molecules of titin.
Biophysical journal 2001;80(2):852-63.
2000: Wu Y; Cazorla O; Labeit D; Labeit S; Granzier H
Changes in titin and collagen underlie diastolic stiffness diversity of cardiac muscle.
Journal of molecular and cellular cardiology 2000;32(12):2151-62.
2000: Trombitás K; Redkar A; Centner T; Wu Y; Labeit S; Granzier H
Extensibility of isoforms of cardiac titin: variation in contour length of molecular subsegments provides a basis for cellular passive stiffness diversity.
Biophysical journal 2000;79(6):3226-34.
2000: Bell S P; Nyland L; Tischler M D; McNabb M; Granzier H; LeWinter M M
Alterations in the determinants of diastolic suction during pacing tachycardia.
Circulation research 2000;87(3):235-40.
2000: Freiburg A; Trombitas K; Hell W; Cazorla O; Fougerousse F; Centner T; Kolmerer B; Witt C; Beckmann J S; Gregorio C C; Granzier H; Labeit S
Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity.
Circulation research 2000;86(11):1114-21.
2000: Cazorla O; Freiburg A; Helmes M; Centner T; McNabb M; Wu Y; Trombitás K; Labeit S; Granzier H
Differential expression of cardiac titin isoforms and modulation of cellular stiffness.
Circulation research 2000;86(1):59-67.
2000: Trombitás K; Freiburg A; Greaser M; Labeit S; Granzier H
From connecting filaments to co-expression of titin isoforms.
Advances in experimental medicine and biology 2000;481():405-18.
2000: Granzier H; Helmes M; Cazorla O; McNabb M; Labeit D; Wu Y; Yamasaki R; Redkar A; Kellermayer M; Labeit S; Trombitás K
Mechanical properties of titin isoforms.
Advances in experimental medicine and biology 2000;481():283-300; discussion 300-4.
2000: Kellermayer M S; Smith S; Bustamante C; Granzier H L
Mechanical manipulation of single titin molecules with laser tweezers.
Advances in experimental medicine and biology 2000;481():111-26; discussion 127-8.
2000: Centner T; Fougerousse F; Freiburg A; Witt C; Beckmann J S; Granzier H; Trombitás K; Gregorio C C; Labeit S
Molecular tools for the study of titin's differential expression.
Advances in experimental medicine and biology 2000;481():35-49; discussion 50-2.
1999: Trombitás K; Freiburg A; Centner T; Labeit S; Granzier H
Molecular dissection of N2B cardiac titin's extensibility.
Biophysical journal 1999;77(6):3189-96.
1999: Helmes M; Trombitás K; Centner T; Kellermayer M; Labeit S; Linke W A; Granzier H
Mechanically driven contour-length adjustment in rat cardiac titin's unique N2B sequence: titin is an adjustable spring.
Circulation research 1999;84(11):1339-52.
1999: Gregorio C C; Granzier H; Sorimachi H; Labeit S
Muscle assembly: a titanic achievement?
Current opinion in cell biology 1999;11(1):18-25.
1998: Linke W A; Granzier H
A spring tale: new facts on titin elasticity.
Biophysical journal 1998;75(6):2613-4.
1998: Gregorio C C; Trombitás K; Centner T; Kolmerer B; Stier G; Kunke K; Suzuki K; Obermayr F; Herrmann B; Granzier H; Sorimachi H; Labeit S
The NH2 terminus of titin spans the Z-disc: its interaction with a novel 19-kD ligand (T-cap) is required for sarcomeric integrity.
The Journal of cell biology 1998;143(4):1013-27.
1998: Millevoi S; Trombitas K; Kolmerer B; Kostin S; Schaper J; Pelin K; Granzier H; Labeit S
Characterization of nebulette and nebulin and emerging concepts of their roles for vertebrate Z-discs.
Journal of molecular biology 1998;282(1):111-23.
1998: Trombitás K; Greaser M; Labeit S; Jin J P; Kellermayer M; Helmes M; Granzier H
Titin extensibility in situ: entropic elasticity of permanently folded and permanently unfolded molecular segments.
The Journal of cell biology 1998;140(4):853-9.
1998: Kellermayer M S; Smith S B; Bustamante C; Granzier H L
Complete unfolding of the titin molecule under external force.
Journal of structural biology 1998;122(1-2):197-205.
1998: Trombitás K; Greaser M; French G; Granzier H
PEVK extension of human soleus muscle titin revealed by immunolabeling with the anti-titin antibody 9D10.
Journal of structural biology 1998;122(1-2):188-96.
1997: Granzier H; Kellermayer M; Helmes M; Trombitás K
Titin elasticity and mechanism of passive force development in rat cardiac myocytes probed by thin-filament extraction.
Biophysical journal 1997;73(4):2043-53.
1997: Trombitás K; Granzier H
Actin removal from cardiac myocytes shows that near Z line titin attaches to actin while under tension.
The American journal of physiology 1997;273(2 Pt 1):C662-70.
1997: Kellermayer M S; Smith S B; Granzier H L; Bustamante C
Folding-unfolding transitions in single titin molecules characterized with laser tweezers.
Science (New York, N.Y.) 1997;276(5315):1112-6.
1996: Helmes M; Trombitás K; Granzier H
Titin develops restoring force in rat cardiac myocytes.
Circulation research 1996;79(3):619-26.
1996: Kellermayer M S; Granzier H L
Elastic properties of single titin molecules made visible through fluorescent F-actin binding.
Biochemical and biophysical research communications 1996;221(3):491-7.
1996: Kellermayer M S; Granzier H L
Calcium-dependent inhibition of in vitro thin-filament motility by native titin.
FEBS letters 1996;380(3):281-6.
1996: Granzier H; Helmes M; Trombitás K
Nonuniform elasticity of titin in cardiac myocytes: a study using immunoelectron microscopy and cellular mechanics.
Biophysical journal 1996;70(1):430-42.
1995: Li Q; Jin J P; Granzier H L
The effect of genetically expressed cardiac titin fragments on in vitro actin motility.
Biophysical journal 1995;69(4):1508-18.
1995: Trombitás K; Jin J P; Granzier H
The mechanically active domain of titin in cardiac muscle.
Circulation research 1995;77(4):856-61.
1995: Granzier H L; Irving T C
Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments.
Biophysical journal 1995;68(3):1027-44.

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