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Ainhoa Arina

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Karin Schreiber; Alessandro Sette; John Sidney; Michael T Spiotto; Ralph R Weichselbaum; Ainhoa Arina; Boris Engels; Theodore G Karrison; Donald A Rowley; Hans Schreiber
Spleen cells from young but not old immunized mice eradicate large established cancers.
Rebecca B Liu; Donald A Rowley; Andrea Schietinger; Ainhoa Arina; David C Binder; Eric Butz; Boris Engels; Elizabeth Hyjek; Bana Jabri; Thomas Krausz; Karin Schreiber; Hans Schreiber
Densely granulated murine NK cells eradicate large solid tumors.
Maria C Ochoa; Asis Palazon; Jesus Prieto; Aizea Morales-Kastresana; Oihana Murillo; Carlos Alfaro; Ainhoa Arina; Pedro Berraondo; Juan Dubrot; Erwin H Duitman; Jessica Fioravanti; Sandra Hervas-Stubbs; Jose Medina-Echeverz; Ignacio Melero
Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy.

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2012: Karin Schreiber; Alessandro Sette; John Sidney; Michael T Spiotto; Ralph R Weichselbaum; Ainhoa Arina; Boris Engels; Theodore G Karrison; Donald A Rowley; Hans Schreiber
Spleen cells from young but not old immunized mice eradicate large established cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(9):2526-33.
2012: Rebecca B Liu; Donald A Rowley; Andrea Schietinger; Ainhoa Arina; David C Binder; Eric Butz; Boris Engels; Elizabeth Hyjek; Bana Jabri; Thomas Krausz; Karin Schreiber; Hans Schreiber
Densely granulated murine NK cells eradicate large solid tumors.
Cancer research 2012;72(8):1964-74.
2012: Maria C Ochoa; Asis Palazon; Jesus Prieto; Aizea Morales-Kastresana; Oihana Murillo; Carlos Alfaro; Ainhoa Arina; Pedro Berraondo; Juan Dubrot; Erwin H Duitman; Jessica Fioravanti; Sandra Hervas-Stubbs; Jose Medina-Echeverz; Ignacio Melero
Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapy.
PloS one 2012;7(12):e52370.
2011: Terry H Wu; Karin Schreiber; Ralph R Weichselbaum; Ainhoa Arina; Elena V Efimova; Nikolai N Khodarev; Donald A Rowley; Hans Schreiber
Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
Cancer immunity 2011;11():2.
2009: Oihana Murillo; Juan Dubrot; Asís Palazón; Ainhoa Arina; Arantza Azpilikueta; Carlos Alfaro; Sarai Solano; María C Ochoa; Carmen Berasain; Izaskun Gabari; Jose L Pérez-Gracia; Pedro Berraondo; Sandra Hervás-Stubbs; Ignacio Melero
In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.
European journal of immunology 2009;39(9):2424-36.
2008: Oihana Murillo; Ainhoa Arina; Sandra Hervas-Stubbs; Anjana Gupta; Brandon McCluskey; Juan Dubrot; Asís Palazón; Arantza Azpilikueta; Maria C Ochoa; Carlos Alfaro; Sarai Solano; José L Pérez-Gracia; Babatunde Oyajobi; Ignacio Melero
Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(21):6895-906.
2008: Ainhoa Arina; Oihana Murillo; Juan Dubrot; A Azpilikueta; Izaskun Gabari; J L Perez-Gracia; Carlos Alfaro; Carmen Berasain; Jesús Prieto; S Ferrini; Sandra Hervas-Stubbs; Ignacio Melero
Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells.
Gene therapy 2008;15(7):473-83.
2007: Manuel Rodriguez; Lydia Alvarez-Erviti; Francisco J Blesa; María C Rodríguez-Oroz; Ainhoa Arina; Ignacio Melero; Luís Isaac Ramos; Jose A Obeso
Bone-marrow-derived cell differentiation into microglia: a study in a progressive mouse model of Parkinson's disease.
Neurobiology of disease 2007;28(3):316-25.
2007: Guillermo Mazzolini; Oihana Murillo; Catalina Atorrasagasti; Juan Dubrot; Iñigo Tirapu; Miguel Rizzo; Ainhoa Arina; Carlos Alfaro; Arantza Azpilicueta; Carmen Berasain; José L Perez-Gracia; Alvaro Gonzalez; Ignacio Melero
Immunotherapy and immunoescape in colorectal cancer.
World journal of gastroenterology : WJG 2007;13(44):5822-31.
2007: Ainhoa Arina; Oihana Murillo; Sandra Hervás-Stubbs; Arantza Azpilikueta; Juan Dubrot; Iñigo Tirapu; Eduardo Huarte; Carlos Alfaro; Jose L Pérez-Gracia; Gloria González-Aseguinolaza; Pablo Sarobe; Juan José Lasarte; Amanda Jamieson; Jesús Prieto; David H Raulet; Ignacio Melero
The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFN gamma.
International journal of cancer. Journal international du cancer 2007;121(6):1282-95.
2007: Ainhoa Arina; Oihana Murillo; Juan Dubrot; Arantza Azpilikueta; Carlos Alfaro; Jose L Pérez-Gracia; Maurizio Bendandi; Belen Palencia; Sandra Hervás-Stubbs; Ignacio Melero
Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer.
Expert opinion on biological therapy 2007;7(5):599-615.
2006: Eduardo Huarte; Esther Larrea; Rubén Hernández-Alcoceba; Carlos Alfaro; Oihana Murillo; Ainhoa Arina; Iñigo Tirapu; Arantza Azpilicueta; Sandra Hervás-Stubbs; Sergia Bortolanza; Jose L Pérez-Gracia; Maria Pilar Civeira; Jesús Prieto; José I Riezu-Boj; Ignacio Melero
Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(1):129-38.
2006: Ignacio Melero; Ainhoa Arina; Oihana Murillo; Juan Dubrot; Carlos Alfaro; Jose L Pérez-Gracia; Maurizio Bendandi; Sandra Hervás-Stubbs
Immunogenic cell death and cross-priming are reaching the clinical immunotherapy arena.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2385-9.
2006: Iñigo Tirapu; Eduardo Huarte; Cristiana Guiducci; Ainhoa Arina; Mikel Zaratiegui; Oihana Murillo; Alvaro Gonzalez; Carmen Berasain; Pedro Berraondo; Puri Fortes; Jesús Prieto; Mario P Colombo; Lieping Chen; Ignacio Melero
Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma.
Cancer research 2006;66(4):2442-50.
2006: Carlos Alfaro; Oihana Murillo; Iñigo Tirapu; Arantza Azpilicueta; Eduardo Huarte; Ainhoa Arina; Laura Arribillaga; Jose L Pérez-Gracia; Maurizio Bendandi; Jesús Prieto; Juan José Lasarte; Ignacio Melero
[The immunotherapy potential of agonistic anti-CD137 (4-1BB) monoclonal antibodies for malignancies and chronic viral diseases].
Anales del sistema sanitario de Navarra 2006;29(1):77-96.
2005: Esperanza Feijoó; Carlos Alfaro; Guillermo Mazzolini; Patricia Serra; Iván Peñuelas; Ainhoa Arina; Eduardo Huarte; Iñigo Tirapu; Belen Palencia; Oihana Murillo; Juan Ruiz; Bruno Sangro; José A Richter; Jesús Prieto; Ignacio Melero
Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8.
International journal of cancer. Journal international du cancer 2005;116(2):275-81.
2005: Laura Arribillaga; Pablo Sarobe; Ainhoa Arina; Marta Gorraiz; Francisco Borrás-Cuesta; Juan Ruiz; Jesús Prieto; Lieping Chen; Ignacio Melero; Juan José Lasarte
Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus.
Vaccine 2005;23(27):3493-9.
2005: Guillermo Mazzolini; Carlos Alfaro; Bruno Sangro; Esperanza Feijoó; Juan Ruiz; Alberto Benito; Iñigo Tirapu; Ainhoa Arina; Josu Sola; Maite Herraiz; Felipe Lucena; Cristina Olagüe; Jose Carlos Subtil; Jorge Quiroga; Ignacio Herrero; Belén Sádaba; Maurizio Bendandi; Cheng Qian; Jesús Prieto; Ignacio Melero
Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(5):999-1010.
2005: Ignacio Melero; Ainhoa Arina; Lieping Chen
The many sounds of T lymphocyte silence.
Immunologic research 2005;33(2):135-47.
2005: Eduardo Huarte; Iñigo Tirapu; Ainhoa Arina; Maria Vera; Carlos Alfaro; Oihana Murillo; Belen Palencia; Victoria Busto; Verónica Marín; Guillermo Mazzolini; Ignacio Melero
Intratumoural administration of dendritic cells: hostile environment and help by gene therapy.
Expert opinion on biological therapy 2005;5(1):7-22.
2004: Iñigo Tirapu; Ainhoa Arina; Guillermo Mazzolini; Marina Duarte; Carlos Alfaro; Esperanza Feijoo; Cheng Qian; Lieping Chen; Jesus Prieto; Ignacio Melero
Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens.
International journal of cancer. Journal international du cancer 2004;110(1):51-60.
2003: Oihana Murillo; Ainhoa Arina; Iñigo Tirapu; Carlos Alfaro; Guillermo Mazzolini; Belen Palencia; Ascensión López-Diaz De Cerio; Jesús Prieto; Maurizio Bendandi; Ignacio Melero
Potentiation of therapeutic immune responses against malignancies with monoclonal antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5454-64.
2003: Pablo Sarobe; Juan José Lasarte; Aintzane Zabaleta; Laura Arribillaga; Ainhoa Arina; Ignacio Melero; Francisco Borrás-Cuesta; Jesús Prieto
Hepatitis C virus structural proteins impair dendritic cell maturation and inhibit in vivo induction of cellular immune responses.
Journal of virology 2003;77(20):10862-71.
2003: Ignacio Melero; Izaskun Gabari; Iñigo Tirapu; Ainhoa Arina; Guillermo Mazzolini; Elena Baixeras; Esperanza Feijoo; Carlos Alfaro; Cheng Qian; Jesús Prieto
Anti-ICAM-2 monoclonal antibody synergizes with intratumor gene transfer of interleukin-12 inhibiting activation-induced T-cell death.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3546-54.
2003: Guillermo Mazzolini; Inigo Narvaiza; L A Martinez-Cruz; Ainhoa Arina; Miguel Barajas; JC Galofré; Cheng Qian; José M Mato; Jesús Prieto; Ignacio Melero
Pancreatic cancer escape variants that evade immunogene therapy through loss of sensitivity to IFNgamma-induced apoptosis.
Gene therapy 2003;10(13):1067-78.
2002: Ainhoa Arina; Iñigo Tirapu; Carlos Alfaro; Mercedes Rodríguez-Calvillo; Guillermo Mazzolini; Susana Inogés; Ascensión López; Esperanza Feijoo; Maurizio Bendandi; Ignacio Melero
Clinical implications of antigen transfer mechanisms from malignant to dendritic cells. exploiting cross-priming.
Experimental hematology 2002;30(12):1355-64.
2002: Iñigo Tirapu; Guillermo Mazzolini; Mercedes Rodriguez-Calvillo; Ainhoa Arina; Belen Palencia; Izaskun Gabari; Ignacio Melero
Effective tumor immunotherapy: start the engine, release the brakes, step on the gas pedal,...and get ready to face autoimmunity.
Archivum immunologiae et therapiae experimentalis 2002;50(1):13-8.